Ear, nose, & throat journal最新文献

{"title":"Institutional Experience in Aspirin-Exacerbated Respiratory Disease Yields Favorable Pulmonary and Sinonasal Outcomes.","authors":"Jennifer E Douglas, Si Hao Tang, Ashika Mani, James N Palmer, Nithin D Adappa, Michael A Kohanski, John V Bosso","doi":"10.1177/01455613251356359","DOIUrl":"https://doi.org/10.1177/01455613251356359","url":null,"abstract":"<p><strong>Background: </strong>Aspirin-exacerbated respiratory disease (AERD) is characterized by asthma, chronic rhinosinusitis with polyps, and sensitivity to aspirin (ASA). Optimal treatment requires coordinated medical and surgical management, with prior studies showing that a single-center approach to AERD management yields improved sinonasal patient outcomes. Here, we sought to evaluate whether institutional experience enhances pulmonary and sinonasal outcomes in patients with AERD undergoing functional endoscopic sinus surgery (FESS) followed by ASA desensitization (AD).</p><p><strong>Methods: </strong>Single-center, retrospective cohort study evaluating patients undergoing FESS and AD from 2016 to 2024. Cohorts were defined as \"early\" (2016-2019) and \"late\" (2020-2024). Demographics, clinical history, and quality of life metrics [eg, 22-Item SinoNasal Outcome Test (SNOT-22) score] were assessed. Cohorts were compared with statistical significance defined as <i>P</i> < .05.</p><p><strong>Results: </strong>Two hundred sixty-two patients (n = 145 early, 117 late) met inclusion criteria. The late cohort was younger (mean 49.6 vs 56.4 years, <i>P</i> = .042) with fewer prior surgeries (1.33 vs 2.64, <i>P</i> ≤ .001) at the time of referral. Results showed a reduced need for inhaled corticosteroids and beta-agonists in the late cohort and improved SNOT-22 rhinologic sub-scores in the early post-treatment period (post-FESS, pre-AD; 2-3 months post-treatment; 4-6 months post-treatment), with a reduced need for revision surgery (0% vs 6.9%, <i>P</i> = .010).</p><p><strong>Conclusions: </strong>Greater institutional experience in AERD management yields significantly improved pulmonary outcomes and more rapid improvement in sinonasal outcomes. This was felt to be due to enhanced communication and coordination of care between the allergist and rhinologist, with implications for healthcare expenditures.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251356359"},"PeriodicalIF":0.0,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"The Role of Immunotherapy in Salivary Gland Cancer: A Systematic Review\".","authors":"Shubham Kumar, Ranjana Sah, Rachana Mehta","doi":"10.1177/01455613251345423","DOIUrl":"https://doi.org/10.1177/01455613251345423","url":null,"abstract":"","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251345423"},"PeriodicalIF":0.0,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nerve-Sparing Approach to the Lateral Sphenoid Sinus Recess in a Patient With Multiple Sphenoid Encephaloceles.","authors":"Jakob L Fischer, Elisabeth H Ference, Jivianne T Lee, Jeffrey D Suh","doi":"10.1177/01455613251353646","DOIUrl":"https://doi.org/10.1177/01455613251353646","url":null,"abstract":"<p><p>We present a case of an encephalocele of the lateral recess of the sphenoid sinus and detail the utilization of a nerve-sparing, windowed, pterygopalatine fossa approach to the lateral sphenoid sinus recess in a 37 year-old patient. The patient presented with 15 years of headaches that worsened with stress and head position and 2 weeks onset of unilateral clear rhinorrhea that was similarly worsened by head position. Collected rhinorrhea was positive for β-2 transferrin, and computed tomography was notable for erosion of the roof of the sphenoid sinus at the lateral recess with soft tissue extending into the sphenoid sinus. Magnetic resonance imaging confirmed the presence of a sphenoid encephalocele. The patient underwent a nerve-sparing windowed transpterygoid approach to the skull-base defect. Intraoperatively, 2 discreet skull-base defects were encountered, each with exposed dural tissue that were then repaired with septal cartilage underlay grafts and overlay mucosal grafts. The patient started acetazolamide in the postoperative period and recovered without the recurrence of cerebrospinal fluid leak.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251353646"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144546635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterization of 68 Consecutive Pediatric Vocal Cord Dysfunction Clinic Patients.","authors":"Katherine E White, Jennifer L McCoy, Amber D Shaffer, Raymond C Maguire","doi":"10.1177/01455613251353641","DOIUrl":"https://doi.org/10.1177/01455613251353641","url":null,"abstract":"<p><strong>Purpose: </strong>Objectives were to characterize patients with inducible laryngeal obstruction (ILO), evaluate exercise-induced asthma (EIA) test results, and determine the need for future testing in this population.</p><p><strong>Methods: </strong>A retrospective chart review was performed at a tertiary children's hospital on all pediatric patients seen in the Vocal Cord Dysfunction specialty clinic from February 2018 to February 2020. Demographics, medications, comorbidities, ILO triggers, symptoms, EIA test results, and follow-up otolaryngology and pulmonology appointment information were collected.</p><p><strong>Results: </strong>Sixty-eight patients with ILO were identified at a median age of 14.5 (range: 9-18) years. Most were female (n = 50, 73.5%) and white (n = 65, 95.6%). Nearly all (92.6%) patients were triggered by exercise and 72.1% by laryngopharyngeal reflux. Almost all (98.5%) patients described difficulty breathing when triggered, with a third (35.3%) having stridor. Median time from initial symptoms to presentation was 12 months (range: 3 months-10 years) and median episode duration was 5 minutes (range: 30 seconds-3 hours). EIA testing was performed in 82.4%. Most (96.4%) patients did not exhibit an ILO episode during flexible fiberoptic laryngoscopy.</p><p><strong>Conclusions: </strong>ILO benefits from a multidisciplinary team approach. Patients were triggered primarily by exertion or reflux, though the underlying behavioral health predispositions have not fully been explored.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251353641"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144546633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From Symptom Onset to Death in 5 Days: A Unique Case of Necrotizing Fasciitis With Low LRINEC Score and No Risk Factors.","authors":"Mohsin Mirza, Tyler Pion, Daniel Russo, Carl Moeller","doi":"10.1177/01455613251355136","DOIUrl":"https://doi.org/10.1177/01455613251355136","url":null,"abstract":"","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251355136"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144546634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kimura's Disease in an Elderly Male: A Case Report of Unilateral Painless Submandibular Mass With IgG4-Positive Plasmacytosis.","authors":"Xiangxiang Wang, Xiangyun Qiao, Liaoliang Hao, Jinli Gao, Leping Liang","doi":"10.1177/01455613251350804","DOIUrl":"https://doi.org/10.1177/01455613251350804","url":null,"abstract":"<p><p>This report describes an atypical presentation of Kimura's disease (KD) in a 73 year-old male with painless left mandibular masses, localized swelling, and pruritus. Distinct from classic KD manifestations, the patient was an elderly male exhibited no significant serum eosinophilia, while imaging demonstrated inflammatory changes in the submandibular tissues and cervical lymph nodes. Histopathologic and immunohistochemical analyses confirmed KD with IgG4-positive plasmacytosis. This case highlights the importance of considering KD in the differential diagnosis of head and neck tumors, particularly in elderly patients lacking classic biomarkers. Notably, the marked infiltration of IgG4-positive plasma cells in the affected tissue further suggests a potential overlap between KD and IgG4-related disease mechanisms. These findings emphasize the relevance of incorporating atypical cases in the current body of knowledge.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251350804"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous Laryngeal Abscess: A Diagnostic Conundrum Mimicking Malignancy Resolved With Conservative Treatment.","authors":"Asimakis D Asimakopoulos, Salim Bouayed","doi":"10.1177/01455613251355131","DOIUrl":"https://doi.org/10.1177/01455613251355131","url":null,"abstract":"<p><p>Laryngeal abscesses (LA), though rare in the modern antibiotic era, remain potentially life-threatening, especially when associated with airway obstruction. This case report presents a 55-year-old immunocompetent female, a heavy smoker and alcohol user, who developed a spontaneous supraglottic laryngeal abscess masquerading as a malignant pathology. The patient presented with odynophagia, dysphagia, and dysphonia, along with inspiratory stridor. Fiberoptic endoscopy revealed a mass in the left aryepiglottic fold and ipsilateral vocal fold immobility. Imaging studies demonstrated a supraglottic formation with necrotic features and bilateral cervical lymphadenopathy. After 3 days of intravenous antibiotics and corticosteroids, the patient's symptoms improved, and she was discharged on oral antibiotics. At 14 days, endoscopy confirmed the resolution of the aryepiglottic fold swelling and normal vocal fold mobility. The clinical evolution, including the patient's response to conservative treatment coupled with the laryngeal status at follow-up, ultimately confirmed the diagnosis of a laryngeal abscess rather than a malignancy. The case underscores the importance of considering laryngeal abscess in the differential diagnosis for patients presenting with persistent symptoms and highlights the need for thorough diagnostic evaluation, including imaging and biopsy when malignancy is suspected. Furthermore, it emphasizes the potential effectiveness of conservative treatment with antibiotics, particularly when airway management and timely intervention are prioritized, thus reducing the need for invasive surgical procedures.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251355131"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Review of Olfactory Assessment Methods.","authors":"Kush S Patel, Charles S Ebert, Keonho A Kong","doi":"10.1177/01455613251351770","DOIUrl":"https://doi.org/10.1177/01455613251351770","url":null,"abstract":"<p><strong>Background: </strong>The measurement of olfaction in research has drawn significant attention due to its critical role in diagnosing and monitoring olfactory dysfunction (OD). Olfactory impairments are associated with various disorders, making accurate and reliable testing essential. Current assessment methods can be categorized into subjective and objective measures. Subjective tools provide information to evaluate an individual's perception and awareness of smells. Conversely, psychophysical (objective) measures provide quantifiable data that can detect olfactory impairments with precision but prove to be time-consuming and costly. The reliability of subjective assessments compared with objective methods remains a topic of ongoing investigation. There is a growing need for a comprehensive and efficient approach to measuring olfaction that balances accuracy, cost, and practicality.</p><p><strong>Methods: </strong>This scholarly review examines and compares the outcomes of studies that have evaluated different olfactory assessment tools. Each study was chosen for its popularity among current otolaryngology providers. The effectiveness of these tests was analyzed based on sensitivity in detecting OD, ease of administration, and overall cost-efficiency.</p><p><strong>Results: </strong>Findings highlight the strengths and limitations of both subjective and objective methods. Subjective assessments, while convenient and cost-effective, exhibit variability in reliability due to individual differences in olfactory perception and cognitive biases. Objective tests provide precise and standardized results, but their practical application is limited due to cost, expertise, and duration of testing.</p><p><strong>Conclusions: </strong>Current olfactory assessments present a trade-off between cost, reliability, and practicality. Objective methods are currently the gold standard, but their limitations necessitate the development of more accessible testing. Future research should focus on refining hybrid models that integrate subjective self-reports with validated objective measures to achieve a comprehensive and cost-effective approach to olfactory assessment.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251351770"},"PeriodicalIF":0.0,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient Perceptions of Artificial Intelligence in Otolaryngology-Head and Neck Surgery: An International Study.","authors":"Miguel Mayo-Yáñez, Anais Rameau, Luigi A Vaira, Manon Louvrier, Alvaro Sanchez Barrueco, Ignacio Alcalá-Rueda, Fernando García-Curdi, Lara Mejuto-Torreiro, Alejandro Klein-Rodríguez, Jesús Herranz-Larrañeta, Juan Maza-Solano, Alberto M Saibene, Giorgia Pugliese, Giovanni Briganti, Carlos M Chiesa-Estomba, Francois Simon, Stephane Hans, Robin Baudouin, Alexandra Rodriguez, Didier Dequanter, Sven Saussez, Thomas Radulesco, Justin Michel, Isabelle M Gengler, Matthew R Naunheim, Giovanni Cammaroto, Andrea De Vito, Giannicola Iannella, Valentin Favier, Florent Carsuzaa, Maria R Barillari, Antonino Maniaci, Jerome R Lechien","doi":"10.1177/01455613251351774","DOIUrl":"https://doi.org/10.1177/01455613251351774","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the demographic determinants of patient perception toward the role of artificial intelligence (AI) in otolaryngology-head and neck surgery care.</p><p><strong>Methods: </strong>Outpatients consulting in otolaryngology-head and neck surgery departments of 18 hospitals were surveyed about the perception of the role of AI in health care. The results were analyzed according to the age, gender, patient use of technology, and the level of education.</p><p><strong>Results: </strong>The survey was completed by 1545 patients from Europe and the United States (participation rate: 98.7%). There were 832 (53.9%) females and 669 (43.3%) males. The level of education significantly influences the perception of AI in otolaryngological care with the lowest trust and agreement in patients with the highest education level. The study demonstrated a higher mean overall agreement score for using AI in medicine among daily users of technologies than among others (7.2 ± 1.9 vs 5.6 ± 2.6; <i>P</i> = .001). Females reported more frequent fears about the use of AI in otolaryngology than males. The agreement scores for using AI in medicine significantly decreased with age (<i>P</i> = .001).</p><p><strong>Conclusion: </strong>The perception of AI use in otolaryngology was influenced by age, gender, level of education, and the use of new technologies in daily life. Further studies promoting the use of AI in Western populations can consider demographics for improving the perception of patients toward AI, and an AI literacy component to determine whether lower trust is due to misunderstanding AI capabilities.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251351774"},"PeriodicalIF":0.0,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thyroid Talk on TikTok: A Social Media Analysis of Thyroidectomy Information on TikTok.","authors":"Arianna V Ramirez, Janisah Amirah I Saripada, Ogechukwu Anwaegbu, Viran J Ranasinghe","doi":"10.1177/01455613251353407","DOIUrl":"https://doi.org/10.1177/01455613251353407","url":null,"abstract":"<p><strong>Objective: </strong>To explore public perceptions of thyroidectomy on TikTok by analyzing post-content, creator type, postoperative concerns, content accuracy, and understandability.</p><p><strong>Study design: </strong>Mixed-methods study utilizing qualitative and quantitative analyses.</p><p><strong>Setting: </strong>The TikTok social media platform.</p><p><strong>Methods: </strong>In October 2023, the top 100 public TikTok videos were collected using the search terms \"thyroidectomy,\" \"thyroid removal,\" and \"thyroid surgery.\" Videos were analyzed for engagement metrics (likes, comments, shares, views, length) and scored using the Video Power Index (VPI). Creator type (patient, physician, non-MD/DO healthcare provider, or non-medical), content themes, and tone were categorized. Content accuracy was evaluated based on American Thyroid Association (ATA) guidelines. Patient complaints and postoperative symptoms were noted. Videos offering education or medical advice were assessed for understandability and actionability using the Patient Education Materials Assessment Tool (PEMAT).</p><p><strong>Results: </strong>Most videos (63%) were created by patients; 27% by physicians, 8% by non-MD/DO providers, and 2% by non-medical creators. Negative portrayals of thyroidectomy (39%) were exclusively from patient accounts. Common complaints included neck pain (19%), low energy (9%), hormone imbalance (7%), weight gain (7%), dysphagia (7%), and cosmetic concerns (7%). The most common themes were post-op experiences (36%) and medical education (36%). Physician-created content was 100% accurate per ATA guidelines, while non-medical accuracy was 65%. PEMAT scores from MD/DO videos showed 78.69% understandability and 26.61% actionability. Patient videos had the highest VPI (0.93 and 0.79).</p><p><strong>Conclusion: </strong>TikTok content on thyroidectomy is largely patient-driven, often reflecting negative postoperative experiences. Physicians should increase social media engagement with accurate and actionable content to improve patient education and address prevalent misconceptions.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251353407"},"PeriodicalIF":0.0,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}