{"title":"Mid-Glottic Web in a Professional Voice User in the Setting of Upper Respiratory Infection.","authors":"Corinne Negvesky, Sophia Chen, Travis L Shiba","doi":"10.1177/01455613251347916","DOIUrl":"https://doi.org/10.1177/01455613251347916","url":null,"abstract":"<p><p>Mid-glottic webs are a rare pathology of the vocal folds, with cases only documented within the last decade. The pathophysiology behind the location of this vocal fold lesion may be attributed to the mid-vocal fold being the site of maximal mechanical stress during phonation. While anterior glottic webs and posterior glottic stenosis are well-described vocal fold pathologies, only 4 cases of mid-membranous webs have been reported to date. We present the first case of a mid-glottic web not attributable to smoking, radiation, or intubation, in a 45-year-old female teacher who developed chronic dysphonia in the setting of occupational voice use and prior upper respiratory tract infection. She was treated surgically with cold instrument lysis of the adhesion via microdirect laryngoscopy. Her dysphonia improved without residual web at her 4-month postoperative visit, but she did develop vocal fold nodules. A thorough evaluation of acute dysphonia and dyspnea in heavy voice users should include a workup for this rare laryngeal pathology, particularly given its significant negative impact on the ability of occupational voice users to work, followed by proper postoperative voice therapy and vocal hygiene.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251347916"},"PeriodicalIF":0.0,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144277129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Helena C Cabrera, Jeffrey D Suh, Rebecca D Golgert, Jakob L Fischer
{"title":"A Case of Canine-Transmitted Postoperative <i>Staphylococcus schleiferi</i> Sinusitis.","authors":"Helena C Cabrera, Jeffrey D Suh, Rebecca D Golgert, Jakob L Fischer","doi":"10.1177/01455613251349619","DOIUrl":"https://doi.org/10.1177/01455613251349619","url":null,"abstract":"<p><p>We present the first documented acute bacterial sinus infection with <i>Staphylococcus schleiferi</i> in a 58-year-old male recovering from endoscopic sinus surgery recovering on postoperative oral corticosteroids. The patient reported, within 1 month of surgery, treating an outer ear infection in his dog that was culture positive for <i>Staphylococcus schleiferi</i> and <i>Corynebacterium sp.</i> and developing an acute exacerbation of his sinus symptoms with increased purulent drainage, facial pain, and increased aural fullness. Nasal endoscopy was notable for purulence and thick mucus in multiple sinuses, which was positive on culture for <i>S. schleiferi</i>. He underwent treatment with trimethoprim/sulfamethoxazole that resolved the active infection. <i>S. schleiferi</i> has shown only rare transmission to a human host in both immunocompetent and immunocompromised patients. Often, this bacterial pathogen will present as a skin infection or outer ear infection in canines and serves as the potential source of infection in humans as they treat their canine companions. This marks the first documented case of acute bacterial sinusitis caused by this bacterial pathogen in the human literature and warrants continued observation as another potential zoonotic pathogen that may cause sinus exacerbations in susceptible populations.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251349619"},"PeriodicalIF":0.0,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144277128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Matthew Y Liu, Philip G Chen, Erik K Weitzel, Erin M Lopez
{"title":"Allergic Fungal Rhinosinusitis: A Contemporary Update.","authors":"Matthew Y Liu, Philip G Chen, Erik K Weitzel, Erin M Lopez","doi":"10.1177/01455613251346578","DOIUrl":"https://doi.org/10.1177/01455613251346578","url":null,"abstract":"<p><strong>Objectives: </strong>To provide a contemporary update on the pathophysiology, diagnosis, and treatment of allergic fungal rhinosinusitis (AFRS).</p><p><strong>Methods: </strong>A review article on the pathophysiology, diagnosis, and treatment of AFRS was performed.</p><p><strong>Results: </strong>AFRS is a subtype of chronic rhinosinusitis with nasal polyps characterized by noninvasive fungal hyphae, eosinophilic mucin, and a type 2 inflammatory response, resulting in significant clinical and radiographic presentations. Although a diagnostic criterion has been used since the 1990s, advances in the pathophysiology and treatment of AFRS question the specificity and applicability of such criteria. Furthermore, the development and progression of AFRS are closely associated with the social determinants of health (SDOH) with a possible genetic component that limits sinonasal antifungal activity. Surgery followed by topical corticosteroids and nasal saline irrigations remains the mainstay of treatment with immunotherapy, antifungals, and biologics having a potential role.</p><p><strong>Conclusions: </strong>AFRS is a complex sinonasal inflammatory disease influenced by socioeconomic, genetic, and environmental factors. Future research is needed to investigate the influence of the SDOH on AFRS, advance diagnostic methods to optimize utility in everyday clinical practice and research, and elucidate the role of potential novel medical therapies in the current treatment pathway.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251346578"},"PeriodicalIF":0.0,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144259676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on \"Nomogram to Predict the Risk of External Auditory Canal Stenosis After Endoscopic Surgery: A Retrospective Study\".","authors":"Rachana Mehta, Ranjana Sah","doi":"10.1177/01455613251347845","DOIUrl":"https://doi.org/10.1177/01455613251347845","url":null,"abstract":"","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251347845"},"PeriodicalIF":0.0,"publicationDate":"2025-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144251500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Primary Facial Cutaneous Mucormycosis in a 6 Month-Old Infant: Case Report With Literature Review.","authors":"Yasser ALGhabra, Hossam Alhraki, Vivian Alahmad, Hisham Alshwaikh","doi":"10.1177/01455613251348315","DOIUrl":"https://doi.org/10.1177/01455613251348315","url":null,"abstract":"<p><p>Cutaneous mucormycosis, a rare and life-threatening fungal infection caused by <i>Mucorales</i> species, predominantly affects immunocompromised individuals. This report describes a rapidly progressive case in a 6-month-old immunocompetent infant who presented with necrotic facial lesions progressing to extensive eschar over 2 weeks. Despite prompt histopathological confirmation, radical surgical debridement, and immediate liposomal amphotericin B therapy, the infant succumbed to sudden deterioration 3 months after apparent clinical resolution. Initial biopsies confirmed cutaneous mucormycosis with characteristic broad, pauci-septate hyphae, while repeat biopsies at 1 month showed no residual disease. Laboratory and imaging findings were unremarkable, and fungal cultures remained negative. This case highlights the diagnostic and therapeutic challenges of pediatric mucormycosis, particularly in immunocompetent hosts, and underscores the potential for fatal relapse despite adherence to treatment protocols. The paradoxical outcome emphasizes the need for prolonged antifungal therapy, advanced molecular monitoring, and equitable access to diagnostics in resource-limited settings.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251348315"},"PeriodicalIF":0.0,"publicationDate":"2025-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144251501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Novel Surgery Approaches in Laryngopharyngeal Schwannomas: A Retrospective Analysis.","authors":"Yajun Gu, Zheng Liang, Hao Wei, Junguo Wang, Hui Li, Hao Wu, Ao Li, Xiaoyun Qian","doi":"10.1177/01455613251346588","DOIUrl":"https://doi.org/10.1177/01455613251346588","url":null,"abstract":"<p><strong>Purpose: </strong>Laryngeal schwannoma is a rare condition with limited research. This case series presents cases of laryngeal schwannoma in our department with details on the surgical approaches and prognosis of patients, in order to add more evidence for this setting.</p><p><strong>Methods: </strong>The patients presented with symptoms that suggested diseases in the throat. These patients were examined by laryngoscopy, magnetic resonance imaging (MRI), and computed tomography (CT). Depending on the tumor size and location, trans-oral endoscopic (laser-assisted) resection, or open laryngeal surgery was applied. The open surgery was modified by splitting the thyroid cartilage plate in the middle (not entering the larynx) and separating the inner surface of the thyroid cartilage plate on the affected side.</p><p><strong>Results: </strong>The tumors of all patients were successfully removed. Then, these patients were followed up at the 1st, 3rd, and 6th month after surgery through clinic visits. Laryngoscopy, MRI, and CT were performed to examine the patients, and no recurrences were detected.</p><p><strong>Conclusion: </strong>The changes applied for the procedure presented in the present study have the potential to reduce recovery time and scarring, and help preserve throat function. The investigators consider these as potential alternatives to existing methods for treating laryngeal schwannomas. However, more research is required to refine the methods used to treat schwannomas and to ensure that patients receive the best care.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251346588"},"PeriodicalIF":0.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Study of Early-Nasal Intervention Among Individuals With Nasopharyngeal Cancer to Prevent Radiation-Induced Sinusitis.","authors":"Tianbin Ouyang, Hou Shi, Yaowen Wang, Jianliang Zhou","doi":"10.1177/01455613251347164","DOIUrl":"https://doi.org/10.1177/01455613251347164","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to explore the impact of early-nasal intervention on sinusitis caused by radiation therapy in patients with nasopharyngeal carcinoma (NPC), in order to prevent and reduce the occurrence of radiation-induced sinusitis.</p><p><strong>Methods: </strong>Patients with NPC who were scheduled for intensity-modulated radiation therapy were randomized into an experimental group (n = 40) and a control group (n = 40) with concealed allocation. While the control group received only compound menthol drops, the experimental group received nasal treatments (nasal saline irrigation, corticosteroid nasal spray, and compound menthol drops) during radiation therapy and for 6 months after therapy. Sinusitis-related scores (symptoms scores, nasal endoscopy scores, and MRI findings) and mucociliary transport rate (MTR, mm/min) were collected at different time points of radiation therapy.</p><p><strong>Results: </strong>Before radiation therapy, there were no statistically-significant differences between the 2 groups in terms of sinusitis-related scores, MTR and general conditions (<i>P</i> > .05). Both experimental and control groups showed statistically-significant differences in sinusitis-related scores between time points after radiation therapy (<i>P</i> < .01), sinusitis-related scores peaked at 6 months after radiation therapy, and there were also significant differences in the MTR between time points during radiation therapy (<i>P</i> < .01). Sinusitis-related scores differed significantly between the 2 groups after the completion of radiation therapy and at the 3rd, 6th, and 12th month after radiation therapy (<i>P</i> < .05). At the 3rd and 6th month after radiation therapy, there was a statistically-significant difference in the nasal MTR between the 2 groups (<i>P</i> < .05).</p><p><strong>Conclusions: </strong>The experimental group and the control group showed statistically-significant changes in sinusitis symptoms scores, endoscopic findings, and MRI findings at multiple important time points after radiation therapy. This type of intervention demonstrates significant clinical value and safety.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251347164"},"PeriodicalIF":0.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Longitudinal Study on Early-Auditory Development in Children Who Have Slightly-Asymmetric Hearing Loss and Are Wearing Hearing Aids.","authors":"Xiao-Yun Zhang, Wei-Li Kong, Ning-Ying Song","doi":"10.1177/01455613251345683","DOIUrl":"https://doi.org/10.1177/01455613251345683","url":null,"abstract":"<p><strong>Objectives: </strong>There have been few studies on slightly-asymmetric sensorineural hearing loss (SASHL), and no study to date has reported on the longitudinal development of early-auditory ability in children with SASHL and wearing hearing aids (HAs). Thus, we explored the developmental trajectory of early-auditory ability of children with SASHL who wear HAs, and compared the differences in different types of SASHL (the mild-moderate, moderate-severe, and severe-profound).</p><p><strong>Methods: </strong>We performed a prospective, longitudinal study of 31 children with SASHL who were followed for 18 months. Their early-prelingual auditory development (EPLAD) was evaluated using the Infant-Toddler: Meaningful Auditory Integration Scale (ITMAIS), before wearing HAs and at the 1st, 3rd, 6th, 12th, and 18th month after implementing HAs. A spline function was implemented to describe the observed EPLAD trajectory. A cubic polynomial regression model was used to predict the change in the ITMAIS score over time, and nonparametric tests or the chi-squared test was used to compare differences between groups.</p><p><strong>Results: </strong>ITMAIS scores were statistically-significantly different between all subsequent follow-ups (<i>P</i> < 0.001). We constructed a highly-accurate predictive score of ITMAIS over time (<i>r</i><sup>2</sup> = 0.99) and show that sound detection was always faster than sound recognition. The EPLAD score of the severe-profound group was always lower than those of the moderate-severe group and the severe-profound group (<i>P</i> < 0.05).</p><p><strong>Conclusions: </strong>The EPLAD trajectory of the SASHL children was steepest during the first month after HA fitting and leveled-off gradually thereafter. The more severe the degree of hearing loss, the slower the EPLAD rate, which emphasizes the importance of early intervention. We recommend further longitudinal studies to elucidate the dynamics of the process and individual differences in early-childhood hearing ability.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251345683"},"PeriodicalIF":0.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}