Cureus最新文献

{"title":"Distal Femoral Replacement After Distal Femur Periprosthetic Fracture: A Case Report.","authors":"Rayan Jamal, Hatem A Shaqroon, Mohamad A Ali, Sultan H Farsi","doi":"10.7759/cureus.85188","DOIUrl":"10.7759/cureus.85188","url":null,"abstract":"<p><p>Distal femoral periprosthetic fractures present a complex challenge, particularly in elderly patients with comorbidities and poor bone quality. We report a case of a 62-year-old Saudi female with morbid obesity and a history of bilateral total knee arthroplasty (TKA) who sustained a distal femoral fracture after minor trauma. Due to limited bone stock and fracture proximity to the prosthesis, internal fixation was ruled out. The patient underwent successful revision TKA with distal femoral replacement (DFR). Postoperative recovery was good, and she was discharged on day 4 with a knee range of motion of 0-90°. This case underscores the viability of DFR as a limb-salvaging option, offering immediate weight-bearing and early mobilization.</p>","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 6","pages":"e85188"},"PeriodicalIF":1.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12127015/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144210535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Prevalence and Associated Risk Factors of Coronary Heart Disease in Patients With Gout: A Cross-Sectional Study.","authors":"Sohaib Asghar, Shoaib Asghar, Summayha Mahbub, Asad Riaz, Shahid Farooq, Imran Khan","doi":"10.7759/cureus.85194","DOIUrl":"10.7759/cureus.85194","url":null,"abstract":"&lt;p&gt;&lt;p&gt;Background Long-term gout patients have been linked to increased risk of coronary heart disease (CHD) and its associated comorbidities. Therefore, careful evaluations are necessary to examine the prevalence and the causes of CHD in gout patients. The aim of this research was to identify significant factors associated with CHD in patients with gout along with the prevalence rate. Materials and methods A cross-sectional study was performed on 270 gout patients who attended the specialist outpatient clinic and the medicine department of Sheikh Zayed Medical College & Hospital, Rahim Yar Khan, Pakistan. Data about predictor variables was collected through interviews and standard clinical procedures. Blood samples were taken to measure laboratory variables such as fasting blood sugar (FBS), serum creatinine, cholesterol, triglycerides, high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C). Initially, descriptive statistics along with the chi-square test of association was executed. Finally, logistic regression analysis was performed as a classification method to estimate the odds ratio and confidence interval. Results The findings showed that 108 (40%, n=270) of gout patients experienced CHD with the highest prevalence rate (52; 48%, n1=108) of myocardial infarction (MI). Among all (n=270) patients, 150 (56%) were suffering from gout for more than 10 years, and 161 (60%) were diagnosed with hypertension. Considering p-value&lt;0.05 as significant for the chi-square test, hypertension (p-value=0.001), type 2 diabetes mellitus (T2DM) (p-value=0.004), family history of CHD (p-value=0.001), serum creatinine (p-value=0.02), cholesterol (p-value=0.04), subcutaneous tophi (p-value=0.02), intraosseous tophi (p-value=0.04), and intermittent allopurinol intake (p-value=0.04) were found to be associated with CHD in patients with gout. The logistic regression analysis showed that hypertension (OR=2.70, CI: 1.60-4.58), T2DM (OR=2.08, CI: 1.26-3.42), creatinine (OR=1.77, CI: 1.07-2.93), cholesterol (OR=1.67, CI: 1.02-2.73), HDL-C (OR=0.59, CI: 0.36-0.96), subcutaneous tophi (OR=1.86, CI: 1.09-3.16), intraosseous tophi (OR=2.22, CI: 1.29-3.81), and intermittent allopurinol consumption (OR=1.92, CI: 1.01-3.66) were associated with CHD in patients with gout. Conclusions The study estimated that 40% of patients with chronic gout developed different types of CHD with the highest prevalence of MI, regardless of the duration of gout or treatment of acute attacks. Hypertension, T2DM, obesity, high creatinine, high cholesterol, low HDL-C and presence of intraosseous tophi are found to be significant factors of CHD in gout patients. These findings significantly contributed to medical research to address the risk of CHD among Pakistani patients with gout by controlling these significant associated factors. Gout patients with a positive family history of CHD should also take precautionary measures to avoid heart complications. Nation-w","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 6","pages":"e85194"},"PeriodicalIF":1.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12127019/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144210539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential Prognostic Factors in Low Rectal Cancer Patients Treated With Neoadjuvant Chemoradiation and Abdominoperineal Resection.","authors":"Mohamed I Fahim, Fady Shafeik, Rasha M Allam, Marina Asaad, Mohammad Taher","doi":"10.7759/cureus.85171","DOIUrl":"10.7759/cureus.85171","url":null,"abstract":"<p><p>Aim This study aimed to evaluate the potential prognostic impact of various clinicopathological factors on survival outcomes in patients with low rectal adenocarcinoma treated with neoadjuvant chemoradiation followed by abdominoperineal resection. Methods This retrospective observational cohort study included 174 patients with low rectal adenocarcinoma who were treated and followed up between 2012 and 2019 at the National Cancer Institute - Cairo University. Results The median follow-up period was 71.2 months. The median disease-free survival (DFS) was 69 months, while the median overall survival (OS) was not reached. Multivariate analysis showed that high tumor grade was significantly associated with reduced OS (95% CI: 1.250-7.280; P = 0.014). Additionally, a circumferential resection margin (CRM) of ≤1 mm was significantly associated with reduced DFS (95% CI: 1.604-17.818; P = 0.006). Conclusions The study found no significant prognostic impact of tumor response to neoadjuvant chemoradiation. However, tumor grade and CRM status emerged as potential prognostic factors for survival in this patient population.</p>","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 6","pages":"e85171"},"PeriodicalIF":1.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12126841/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144210536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dual Glucagon-Like Peptide-1 (GLP-1) and Glucose-Dependent Insulinotropic Polypeptide (GIP) Receptor Agonist-Associated Thyroiditis: A Case Report of Thyroid Dysfunction Following Tirzepatide Use.","authors":"Sara Humaida, Kamar Manzalji, Naheel Seyam, Lolwa Al-Masalmani","doi":"10.7759/cureus.85123","DOIUrl":"10.7759/cureus.85123","url":null,"abstract":"<p><p>Drug-induced thyroiditis is an uncommon but clinically important condition. As dual glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonists like tirzepatide are increasingly used for weight management and blood sugar control, there is growing interest in understanding their potential thyroid-related effects. We report a 32-year-old woman with no personal or family history of thyroid disease who developed painless biphasic thyroiditis, initial thyrotoxicosis followed by transient hypothyroidism, after two months of tirzepatide therapy. Thyroid autoantibodies were negative, and ultrasound showed heterogeneous echotexture with increased vascularity, consistent with thyroiditis. Infectious, autoimmune, postpartum, and infiltrative causes were excluded based on clinical history, laboratory findings, and imaging. Thyroid function normalized two months after discontinuing tirzepatide without the need for treatment. This case highlights a possible association between tirzepatide and drug-induced painless thyroiditis. It adds to the limited literature and emphasizes the need for clinician awareness of this possible adverse effect.</p>","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 5","pages":"e85123"},"PeriodicalIF":1.0,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12127604/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144210481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Strategic Care of Ballistic Injuries: A Retrospective Observational Study at a Moroccan Military Hospital.","authors":"S Khalkane, Monsef Elabdi, Issam Serghini, Youssef Qamouss, Rachid Seddiki","doi":"10.7759/cureus.85162","DOIUrl":"10.7759/cureus.85162","url":null,"abstract":"&lt;p&gt;&lt;p&gt;Background Ballistic trauma from high-velocity projectiles causes severe multisystem injury and rapid physiological decline. While well-characterized in combat and civilian violence, accidental firearm injuries during military training remain understudied. These incidents typically affect young, unprotected individuals in settings with limited prehospital care factors that may influence injury patterns and outcomes. This study aims to describe the clinical features, injury profiles, and management of accidental ballistic trauma in a military training context, with implications for prevention, triage, and critical care in resource-limited settings. Methods We conducted a six-year retrospective observational study (2016-2021) at Hassan II Military Hospital, Morocco, including 32 consecutive male patients admitted to the intensive care unit (ICU) for accidental high-velocity ballistic trauma sustained during military training. Injuries were caused by North Atlantic Treaty Organization (NATO)-standard live ammunition (5.56 × 45 mm or 7.62 × 51 mm). No exclusions were applied. Data collected included demographics, injury characteristics, prehospital care, hemodynamic parameters at admission, surgeries, and outcomes. ICU admission followed institutional protocols based on hemodynamic instability, high trauma burden, or need for invasive support. Outcomes were classified as favorable (ICU discharge without major complications) or unfavorable (mortality, organ failure, or reoperation). The study received ethics approval from the Institutional Committee of Hassan II Military Hospital. Results The mean age was 30.7 years; half of the patients were aged 31-40. Multiregional injuries were frequent: limb trauma (50%), abdominal injury (37.5%), and neurological impairment (Glasgow Coma Scale (GCS): 9-13 in 37.5%). On ICU admission, tachypnea (62.5%), tachycardia (50%), and hypotension (37.5%) were common. Most patients (87.5%) underwent surgery (60% orthopedic and 40% abdominal), with a mean delay of 13.2 ± 7.3 hours, mainly due to prehospital transfer and imaging delays. Intensive monitoring was required in 62.5%. Injury Severity Score (ISS) ranged from 12 to 32, indicating moderate-to-severe trauma in over one-third of patients. Favorable outcomes were observed in 62.5%. Unfavorable outcomes (37.5%), including mortality and reoperation, were significantly associated with older age, comorbidities, hypotension, mean arterial pressure (MAP) &lt; 65 mmHg, and oliguria (p &lt; 0.05). Conclusion Accidental ballistic trauma during military training is associated with significant morbidity and mortality, particularly when early hemodynamic instability is present. Findings support early triage, aggressive resuscitation, and application of damage control principles at the point of injury (\"damage control at ground zero\") as critical strategies. Although limited by its retrospective, single-center design and small sample, this study provides foundational evidence to gu","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 5","pages":"e85162"},"PeriodicalIF":1.0,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12126751/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144201160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From Velocity to Acceleration: A Perspective on Age-Related Visual Field Progression in Glaucoma.","authors":"Masaki Tanito, Tomoki Shirakami","doi":"10.7759/cureus.85129","DOIUrl":"https://doi.org/10.7759/cureus.85129","url":null,"abstract":"<p><p>The conventional evaluation of visual field (VF) progression in glaucoma often relies on linear regression to estimate the rate of decline, focusing on velocity (dB/year). However, this approach may underestimate future progression, particularly in elderly patients. This editorial highlights the importance of incorporating acceleration (dB/year²) into clinical assessments of VF loss. Using physiological and pathological models, we demonstrate that VF sensitivity decline is inherently nonlinear with age. A cubic model illustrates age-related sensitivity loss in healthy eyes, while a quadratic model captures the interaction between disease duration and baseline age in glaucomatous eyes. These models emphasize that progression accelerates over time and suggest that individualized treatment intensity should consider not only the current rate of VF decline but also its likely acceleration based on patient age and disease course.</p>","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 5","pages":"e85129"},"PeriodicalIF":1.0,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12131105/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144217826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating Avoidable Transfers of Pediatric Forearm Fractures to the Emergency Department.","authors":"Adrianna Kowblansky, Andrew Fealy, Sarah Dance, Adam Mansour, Kevin Cleary, Sean A Tabaie","doi":"10.7759/cureus.85103","DOIUrl":"10.7759/cureus.85103","url":null,"abstract":"<p><p>Background Forearm fractures represent approximately 20% of pediatric fractures and are commonly managed in emergency departments (EDs). While minimally displaced fractures require immobilization, displaced fractures necessitate reduction. Many non-pediatric facilities lack the resources to manage these fractures, leading to frequent transfers to pediatric emergency departments (PEDs). This study aims to evaluate the rate of avoidable transfers of pediatric forearm fractures to a PED and identify risk factors contributing to unnecessary transfers. Methods A retrospective cross-sectional study was conducted at a single tertiary pediatric hospital from July 1, 2022, to June 30, 2023. Patients aged 0-17 years treated for forearm fractures were identified using ICD-10 codes. Exclusion criteria included patients not transferred, incomplete treatment data, or missing initial radiographs. Collected variables encompassed demographics, fracture characteristics, transfer details, and treatments performed. Statistical analyses included chi-square tests for categorical variables and Mann-Whitney U tests for continuous variables, with significance set at p < 0.05. Results Out of 445 patients identified, 161 met the inclusion criteria. The mean age was 8.0 years (SD 3.9); 70.8% were male, and 31.7% were African Americans. Avoidable transfers, defined as patients who did not require reduction or surgical intervention, accounted for 38 cases (23.6%). Non-displaced fractures were significantly associated with avoidable transfers (p < 0.001). Race was also significant, with higher rates of avoidable transfer among African American patients (42.1%) and patients of other races (47.4%) compared to Caucasian patients (10.5%) (p = 0.006). There was a statistically significant association between the source of appropriate and avoidable transfers (p = 0.012), with cases originating from clinics (n = 7), outside hospitals (n = 24), and urgent care centers (n = 7). Multivariate logistic regression identified younger age as the only significant factor associated with avoidable transfer (p = 0.047, OR: 0.74, CI: 0.5-0.98). Conclusions A significant proportion of pediatric forearm fracture transfers to the PED were avoidable, primarily due to patients not requiring reduction or surgical intervention. Younger age was a significant factor associated with unnecessary transfers. Enhancing education on pediatric fracture management and establishing clear guidelines may reduce unnecessary transfers, optimize resource utilization, and alleviate burdens on specialized centers.</p>","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 5","pages":"e85103"},"PeriodicalIF":1.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12124921/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144201157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Robot-Assisted Multiquadrant Operation: Proctocolectomy and Abdominoperineal Resection Using the Da Vinci Xi for Familial Adenomatous Polyposis With Rectal Carcinoma.","authors":"Turgay Kalinov, Aleksandar Zlatarov, Nikola Kolev, Krasimir D Ivanov","doi":"10.7759/cureus.85107","DOIUrl":"10.7759/cureus.85107","url":null,"abstract":"<p><p>Familial adenomatous polyposis (FAP) is a rare inherited disorder that is characterized by the formation of multiple adenomatous polyps in the colon that are precancerous. Diagnosis of the disease is of utmost importance in patients with a history of FAP, and prophylactic fibrocolonoscopies should be performed as early as the teenage years. This rare but significant genetic condition usually manifests in late adolescence or early adult years. The clinical case highlights the importance of a multidisciplinary approach and the need for early diagnosis and treatment in patients with FAP. The da Vinci Xi robotic system (Intuitive Surgical, CA, USA) has been successfully applied in multiquadrant operations such as total colectomy with abdominoperineal extirpation of the rectum. We present the case of a 38-year-old man admitted to our clinic, the First Clinic of Surgery in University Hospital Saint Marina, Varna, Bulgaria, in late 2022 with complaints of blood in stool and abnormal defecation rhythm. The fibrocolonoscopy found a tumor formation at 4 cm of the anorectal junction, a second tumor formation at 10 cm, and multiple colonic polyposis. Biopsies taken from the suspected areas confirmed the presence of two rectal carcinomas and adenomatous polyposis in the remaining areas. Neoadjuvant radiotherapy and chemotherapy with capecitabine 1600 mg were performed. Persistent carcinoma was an indication for performing robot-assisted proctocolectomy combined with abdominoperineal resection of the rectum. The robotic platform we used was the da Vinci Xi, a single-docking patient platform with three boom repositioning. The patient was followed for 24 months postoperatively. Recovery was uneventful, with no major complications. The terminal ileostomy functioned well, and the patient adapted successfully to stoma care. During follow-up, no local or systemic recurrence of the oncological disease was observed, and surveillance imaging remained clear throughout the period. This clinical case provides an important example of the multidisciplinary approach in the diagnosis and treatment of FAP. Neoadjuvant therapy, including radiotherapy and chemotherapy followed by robot-assisted surgery, demonstrates the significant potential of modern treatment approaches. Robot-assisted proctocolectomy is a relatively new approach whose advantages and disadvantages are yet to be explored. Collaboration between gastroenterologists, oncologists, radiologists, and surgeons is essential for the comprehensive management of such complex cases. Finally, this clinical case highlights the need for long-term surveillance of patients with FAP for early detection and management of potential recurrences or new disease.</p>","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 5","pages":"e85107"},"PeriodicalIF":1.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12125362/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144201216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Integration of Artificial Intelligence Into Precision Medicine for Neuro-Oncology: Ethical, Clinical, and Nursing Implications in Immunotherapy Care.","authors":"Victoria M Ajibade, Chidinma S Madu","doi":"10.7759/cureus.85024","DOIUrl":"10.7759/cureus.85024","url":null,"abstract":"<p><p>This paper explores how artificial intelligence (AI) is being woven into precision medicine for neuro-oncology, highlighting its ethical, clinical, and nursing implications in the realm of immunotherapy. With AI-powered diagnostics and predictive analytics, we're seeing a boost in treatment accuracy, which paves the way for more personalized and effective care. On the clinical side, AI is fine-tuning targeted therapies, leading to better patient outcomes and less treatment-related toxicity. However, ethical concerns pop up around data privacy, algorithmic bias, and fair access to these AI-driven treatments. Nurses are at the forefront of tackling these issues, ensuring that care remains patient-centered, monitoring AI-assisted interventions, and grappling with ethical challenges. Their role in education and advocacy is crucial in connecting the dots between AI innovations and compassionate care. As AI continues to advance, it's vital for different disciplines to work together to tap into its potential while maintaining ethical standards and enhancing care in neuro-oncology.</p>","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 5","pages":"e85024"},"PeriodicalIF":1.0,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12121462/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144183122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retraction: Congenital Hydronephrosis Due to Pyeloureteral Atresia: A Case Report.","authors":"Zainab H Alowainati, Zainab H Salman, Hibah A Alhamad, Njood Alsudairy","doi":"10.7759/cureus.r182","DOIUrl":"10.7759/cureus.r182","url":null,"abstract":"<p><p>[This retracts the article DOI: 10.7759/cureus.76664.].</p>","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 5","pages":"r182"},"PeriodicalIF":1.0,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12121935/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144183149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}