Archivos de cardiologia de Mexico最新文献

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Surgical approach with minimally invasive intervention in lusoria dysphagia. 微创手术治疗吞咽困难。
Archivos de cardiologia de Mexico Pub Date : 2024-07-09 DOI: 10.24875/ACM.24000072
Carlos Alcántara-Noguez, Desireé Leines-Castelán, Aarón E Buenabad-Hernández, Alejandra Contreras-Ramos, Sergio Ruiz-González, Patricia Romero-Cardenas, Alejandro Bolio-Cerdan
{"title":"Surgical approach with minimally invasive intervention in lusoria dysphagia.","authors":"Carlos Alcántara-Noguez, Desireé Leines-Castelán, Aarón E Buenabad-Hernández, Alejandra Contreras-Ramos, Sergio Ruiz-González, Patricia Romero-Cardenas, Alejandro Bolio-Cerdan","doi":"10.24875/ACM.24000072","DOIUrl":"https://doi.org/10.24875/ACM.24000072","url":null,"abstract":"<p><p>The lusoria artery has a prevalence of 0.5-2% in the general population. The abnormal development of the aortic arch forms vascular rings around the trachea and esophagus, causing pressure on them and leading to characteristic symptoms such as chest pain, difficulty breathing, and/or swallowing. Conventionally, only the subclavian artery was severed to release the esophagus, as done in neonates. However, this can lead to long-term hypotrophy of the thoracic limb. The surgical intervention remains controversial, with limitations, and it is only to be performed when the patient presents with symptoms. In the following two cases, a two-stage minimally invasive approach is described: first, a left lateral minithoracotomy for lusoria artery sectioning, and second, a supraclavicular approach for reimplantation into the right carotid artery.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141565324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Factors associated with left ventricular diastolic dysfunction in adults from a region of the Andes in Peru]. [秘鲁安第斯地区成年人左心室舒张功能障碍的相关因素]。
Archivos de cardiologia de Mexico Pub Date : 2024-07-09 DOI: 10.24875/ACM.23000217
Aníbal V Díaz-Lazo, Mely Ruiz-Aquino, Hugo Arroyo-Hernández
{"title":"[Factors associated with left ventricular diastolic dysfunction in adults from a region of the Andes in Peru].","authors":"Aníbal V Díaz-Lazo, Mely Ruiz-Aquino, Hugo Arroyo-Hernández","doi":"10.24875/ACM.23000217","DOIUrl":"10.24875/ACM.23000217","url":null,"abstract":"<p><strong>Objective: </strong>To determine the factors associated with left ventricular diastolic dysfunction (LVDD) in adults residing in a region of the Andes in Peru.</p><p><strong>Method: </strong>A case-control study was conducted on adults living at an altitude of more than 3000 meters in Peru. Cases consisted of patients diagnosed with LVDD through echocardiography, whereas controls were adults without LVDD, as confirmed by echocardiography.</p><p><strong>Results: </strong>A total of 50 cases and 100 controls were included in the study. Among them, 38.7% had high blood pressure, and 41.3% were overweight. Upon adjusted analysis, age 60 or older (aOR: 4.06; 95%CI: 1.29-12.8), female sex (aOR: 2.24; 95%CI: 1.01-4.96) and left ventricular hypertrophy (aOR: 3.17; 95%CI: 1.41-7.17) were identified as statistically significant factors associated with LVDD.</p><p><strong>Conclusions: </strong>The risk of LVDD is associated with older adults, female gender, and left ventricular hypertrophy among individuals residing above 3000 meters altitude in a region of the Andes, in Peru.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":"444-450"},"PeriodicalIF":0.0,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141565323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Double coronary fistula: a rare finding in a pediatric patient]. [双冠状动脉瘘:儿科患者的罕见发现]。
Archivos de cardiologia de Mexico Pub Date : 2024-06-17 DOI: 10.24875/ACM.24000069
Paola S García-Vargas, José L Colín-Ortiz, Jorge A Silva-Estrada, Brenda M Gutiérrez-Anguiano, Andrea Nava-Celis
{"title":"[Double coronary fistula: a rare finding in a pediatric patient].","authors":"Paola S García-Vargas, José L Colín-Ortiz, Jorge A Silva-Estrada, Brenda M Gutiérrez-Anguiano, Andrea Nava-Celis","doi":"10.24875/ACM.24000069","DOIUrl":"https://doi.org/10.24875/ACM.24000069","url":null,"abstract":"","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141422155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effectiveness of the CNIC polypill in secondary cardiovascular prevention in the subgroup of patients of the NEPTUNO study using atorvastatin doses of 20 mg]. [在使用阿托伐他汀剂量为 20 毫克的 NEPTUNO 研究亚组患者中,CNIC 多效丸对心血管二级预防的有效性]。
Archivos de cardiologia de Mexico Pub Date : 2024-06-06 DOI: 10.24875/ACM.23000230
José R González-Juanatey, Alberto Cordero, Luis Masana, Regina Dalmau
{"title":"[Effectiveness of the CNIC polypill in secondary cardiovascular prevention in the subgroup of patients of the NEPTUNO study using atorvastatin doses of 20 mg].","authors":"José R González-Juanatey, Alberto Cordero, Luis Masana, Regina Dalmau","doi":"10.24875/ACM.23000230","DOIUrl":"10.24875/ACM.23000230","url":null,"abstract":"<p><strong>Objective: </strong>To analyse the incidence and risk of recurrent major adverse cardiovascular events (MACE), level of risk factor control, treatment persistence and cost of the CNIC polypill version containing acetylsalicylic acid (ASA) 100 mg, atorvastatin 20 mg (A20), and ramipril 2.5, 5.0 or 10 mg in secondary cardiovascular prevention patients.</p><p><strong>Method: </strong>Subanalysis of the observational, retrospective, multicentre, NEPTUNO study in patients treated for two years with the CNIC polypill A20, the same monocomponents as single drugs, equipotent drugs, and other therapies.</p><p><strong>Results: </strong>922 patients were included in each group. The risk of recurrent MACE was lower among CNIC A20 polypill users than all others (21%, 23% and 26% increased risk among the monocomponents, equipotent or other therapy cohorts, respectively; p < 0.05). The magnitude of the mean change in low-density lipoprotein cholesterol and blood pressure, as well as the increase in the proportion of patients achieving target goals, was also greater among patients treated with the CNIC A20 polypill than in any of the other cohorts (all p < 0.001). Treatment persistence was significantly higher in patients treated with the CNIC A20 polypill (p < 0.001) and was a less costly strategy than any other therapeutic option.</p><p><strong>Conclusions: </strong>In patients in secondary cardiovascular prevention, the CNIC A20 polypill (ASA 100 mg, atorvastatin 20 mg, and ramipril 2.5, 5.0 or 10 mg) constitutes a valid therapeutic option with similar benefits and outcomes to the version of the polypill with atorvastatin 40 mg.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":"429-443"},"PeriodicalIF":0.0,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141285620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of the osteoprotegerin/RANKL/RANK axis and osteopontin in acute coronary syndrome. 骨保护素/RANKL/RANK 轴和骨素在急性冠状动脉综合征中的作用。
Archivos de cardiologia de Mexico Pub Date : 2024-05-29 DOI: 10.24875/ACM.24000037
Juan A Vega-Rosales, Huitzilihuitl Saucedo-Orozco, Ricardo Márquez-Velasco, Randall Cruz-Soto, Daniel F Zazueta-Salido, Solange G Koretzky, Gustavo Salinas-Arteaga, Verónica Guarner-Lans, Linaloe Pech-Manzano, Israel Pérez-Torres, Claudia Tavera-Alonso, Ma Elena Soto
{"title":"The role of the osteoprotegerin/RANKL/RANK axis and osteopontin in acute coronary syndrome.","authors":"Juan A Vega-Rosales, Huitzilihuitl Saucedo-Orozco, Ricardo Márquez-Velasco, Randall Cruz-Soto, Daniel F Zazueta-Salido, Solange G Koretzky, Gustavo Salinas-Arteaga, Verónica Guarner-Lans, Linaloe Pech-Manzano, Israel Pérez-Torres, Claudia Tavera-Alonso, Ma Elena Soto","doi":"10.24875/ACM.24000037","DOIUrl":"https://doi.org/10.24875/ACM.24000037","url":null,"abstract":"<p><strong>Objectives: </strong>The primary objective of this study is to ascertain the levels of osteoprotegerin (OPG) and osteopontin (OPN), alongside osteoprotegerin/RANKL ratio (ORR), and assess their association with the SYNTAX score and ascertain the potential of these molecules as predictive markers for risk, aiding in risk stratification. Eventually, they could potentially be employed even before angiography to gauge the severity of coronary lesions.</p><p><strong>Methods: </strong>Prospective study with 147 participants, 101 (69%) were men, with an average age of 60. We included three groups - (1) patients with acute coronary syndrome undergoing percutaneous coronary intervention (ACS-PCI), (2) patients without ACS who underwent coronary angiography for an indication other than ischemia and did not undergo PCI (non-ACS without), and (3) one asymptomatic subject. OPG and OPN were measured. ORR and SYNTAX scores were calculated. The association between OPG and OPN levels and important clinical variables was investigated.</p><p><strong>Results: </strong>OPG levels in Group 1 were lower compared to Groups 2 and 3 (controls), Group 1 (490 pg/mL) versus Group 2 (829 pg/mL) versus Group 3 (845 pg/mL) (p = 0.001). OPG had lower levels in patients with coronary artery stenosis versus without stenosis. A decrease in ORR was shown in all groups and no association with the SYNTAX score.</p><p><strong>Conclusion: </strong>OPG and OPN (and ORR) levels are decreased in patients with ACS and show no correlation with the SYNTAX score. As an exploratory study, our work suggest that increased OPG and OPN levels in non-ACS patients may have, in fact, a protective effect. This study is one of the few with an appropriate control in ACS and reproducibility is necessary mainly with multicenter studies.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141177079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Incidence of intrahospitalary major cardiac events with the use of mechanic thromboaspiration versus only use of IIB/IIIA glucoprotein inhibitors on patients with acute ST elevation myocardial infarction]. [对急性 ST 段抬高型心肌梗死患者使用机械溶栓疗法与仅使用 IIB/IIIA 糖蛋白抑制剂相比,院内重大心脏事件的发生率]。
Archivos de cardiologia de Mexico Pub Date : 2024-05-29 DOI: 10.24875/ACM.23000228
Arcenio A Lendo-López, José E Galván-García, Anival Trujillo-García, Luis F Aguilar-Aguilar, Jorge A Garay-Hansen, Omar Ramírez-Lastra, Óscar Zapana-Céspedes, Bernardo Meléndez-Mendoza, Ramiro J Fajardo-Losada, Salvador I Sandoval-Hernández, Alan A León-Bojorquez, Luis A González-Serrato, Kevin A Zurroza-Luna, Juan M Palacios-Rodríguez
{"title":"[Incidence of intrahospitalary major cardiac events with the use of mechanic thromboaspiration versus only use of IIB/IIIA glucoprotein inhibitors on patients with acute ST elevation myocardial infarction].","authors":"Arcenio A Lendo-López, José E Galván-García, Anival Trujillo-García, Luis F Aguilar-Aguilar, Jorge A Garay-Hansen, Omar Ramírez-Lastra, Óscar Zapana-Céspedes, Bernardo Meléndez-Mendoza, Ramiro J Fajardo-Losada, Salvador I Sandoval-Hernández, Alan A León-Bojorquez, Luis A González-Serrato, Kevin A Zurroza-Luna, Juan M Palacios-Rodríguez","doi":"10.24875/ACM.23000228","DOIUrl":"10.24875/ACM.23000228","url":null,"abstract":"<p><strong>Objective: </strong>To identify the incidence of in-hospital major adverse cardiac events (MACE) with the use of mechanic thromboaspiration plus IIb/IIIa glycoprotein inhibitors versus only use of IIb/IIIa glycoprotein inhibitors on patients with acute ST elevation myocardial infarction.</p><p><strong>Method: </strong>Retrospective, observational, cohort analytic study, on patients with acute ST elevation myocardial infarction that had angiography thrombus TIMI 5 grade, treated between October 2021 and December 2022.</p><p><strong>Results: </strong>A total of 237 patients were included. In 113 patients thromboaspiration were used, 124 patients didn't used. 81.6% were men. In-hospital MACE occurred on 31.9% of patients with thromboaspiration use vs. 30.6% on patients with no use (RR: 1.05; IC95%: 0.61-1.93; p = 0.840). Incidence of malignant arrhythmias were of 8% with thromboaspiration use vs. 1.6% on patients with no use (RR: 5.27; IC95%: 1.11-24.97; p = 0.020).</p><p><strong>Conclusions: </strong>The use of thromboaspiration on concomitant treatment with IIb/IIIa glycoprotein inhibitors was similar with only IIb/IIIa glycoprotein inhibitors in reducing incidence of in-hospital MACE on patients with ST elevation acute myocardial infarction and high thrombus burden. The study has several limitations, so results should be taken with caution.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":"467-473"},"PeriodicalIF":0.0,"publicationDate":"2024-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141177077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Cardiovascular manifestations in pediatric multisystem inflammatory syndrome associated with COVID-19 in a tertiary care pediatric center in Mexico City]. [墨西哥城一家三级儿科中心与 COVID-19 相关的小儿多系统炎症综合征的心血管表现]。
Archivos de cardiologia de Mexico Pub Date : 2024-05-16 DOI: 10.24875/ACM.23000205
M. J. Granda-Jiménez, Itzel E Rios-Olivares, Carlos González-Rebeles-Guerrero, M. P. Márquez-Aguirre, J. A. Gutiérrez-Hernández, Laura Camacho-Reyes, Jesús De Rubens-Figueroa, Carlos A Corona-Villalobos
{"title":"[Cardiovascular manifestations in pediatric multisystem inflammatory syndrome associated with COVID-19 in a tertiary care pediatric center in Mexico City].","authors":"M. J. Granda-Jiménez, Itzel E Rios-Olivares, Carlos González-Rebeles-Guerrero, M. P. Márquez-Aguirre, J. A. Gutiérrez-Hernández, Laura Camacho-Reyes, Jesús De Rubens-Figueroa, Carlos A Corona-Villalobos","doi":"10.24875/ACM.23000205","DOIUrl":"https://doi.org/10.24875/ACM.23000205","url":null,"abstract":"Objective\u0000The objective is to expose the cardiovascular alterations in patients diagnosed with pediatric inflammatory multisystem syndrome (PIMS) associated with COVID-19 during the SARS-CoV-2 pandemic, in order to understand the disease, its evolution, and optimal management upon diagnosis.\u0000\u0000\u0000Method\u0000Retrospective, observational, cross-sectional analytical study of patients diagnosed with PIMS according to the criteria of the World Health Organization at the National Institute of Pediatrics, from March 2020 to December 2021.\u0000\u0000\u0000Results\u0000During the study period, 77 patients with PIMS were diagnosed. The results showed correlation between the shock state and alteration of laboratory markers (platelets 144217.29 ± 139321.6 μL [p < 0.001], procalcitonin 27.37 ± 38.37 ng/ml [p = 0.05] and ferritin 1937.87 ± 2562.63 [p < 0.001]). The ventricular function in patients with shock was significantly lower compared to those without shock (49.6 ± 9.1% vs. 58.1 ± 8.4 %; t-Student p < 0.001), as well as injury to the left coronary artery (p = 0.02). There is a correlation between NT-proBNP and ventricular dysfunction (Kruskal-Wallis p = 0.007). Statistical significance was found in the association between death, elevation of inflammatory markers and ventricular dysfunction (p < 0.001).\u0000\u0000\u0000Conclusions\u0000The cardiovascular alterations observed, in order of frequency, were pericardial effusion (25.7%), myocarditis (15%), mild ventricular dysfunction (13.5%) and small coronary aneurysm with predominance of the left coronary artery and the anterior descending one.","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":"44 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140969840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Cardiovascular manifestations in pediatric multisystem inflammatory syndrome associated with COVID-19 in a tertiary care pediatric center in Mexico City]. [墨西哥城一家三级儿科中心与 COVID-19 相关的小儿多系统炎症综合征的心血管表现]。
Archivos de cardiologia de Mexico Pub Date : 2024-05-16 DOI: 10.24875/ACM.23000205
Mercy J Granda-Jiménez, Itzel E Rios-Olivares, Carlos González-Rebeles-Guerrero, Martha P Marquez-Aguirre, José A Gutiérrez-Hernández, Laura Camacho-Reyes, Jesús De Rubens-Figueroa, Carlos A Corona-Villalobos
{"title":"[Cardiovascular manifestations in pediatric multisystem inflammatory syndrome associated with COVID-19 in a tertiary care pediatric center in Mexico City].","authors":"Mercy J Granda-Jiménez, Itzel E Rios-Olivares, Carlos González-Rebeles-Guerrero, Martha P Marquez-Aguirre, José A Gutiérrez-Hernández, Laura Camacho-Reyes, Jesús De Rubens-Figueroa, Carlos A Corona-Villalobos","doi":"10.24875/ACM.23000205","DOIUrl":"10.24875/ACM.23000205","url":null,"abstract":"<p><strong>Objective: </strong>The objective is to expose the cardiovascular alterations in patients diagnosed with pediatric inflammatory multisystem syndrome (PIMS) associated with COVID-19 during the SARS-CoV-2 pandemic, in order to understand the disease, its evolution, and optimal management upon diagnosis.</p><p><strong>Method: </strong>Retrospective, observational, cross-sectional analytical study of patients diagnosed with PIMS according to the criteria of the World Health Organization at the National Institute of Pediatrics, from March 2020 to December 2021.</p><p><strong>Results: </strong>During the study period, 77 patients with PIMS were diagnosed. The results showed correlation between the shock state and alteration of laboratory markers (platelets 144217.29 ± 139321.6 μL [p < 0.001], procalcitonin 27.37 ± 38.37 ng/ml [p = 0.05] and ferritin 1937.87 ± 2562.63 [p < 0.001]). The ventricular function in patients with shock was significantly lower compared to those without shock (49.6 ± 9.1% vs. 58.1 ± 8.4 %; t-Student p < 0.001), as well as injury to the left coronary artery (p = 0.02). There is a correlation between NT-proBNP and ventricular dysfunction (Kruskal-Wallis p = 0.007). Statistical significance was found in the association between death, elevation of inflammatory markers and ventricular dysfunction (p < 0.001).</p><p><strong>Conclusions: </strong>The cardiovascular alterations observed, in order of frequency, were pericardial effusion (25.7%), myocarditis (15%), mild ventricular dysfunction (13.5%) and small coronary aneurysm with predominance of the left coronary artery and the anterior descending one.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":"276-285"},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11259421/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140960429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[New concepts in the physiopathology of hypertension. Purinergic receptors]. [高血压生理病理学的新概念:嘌呤能受体]。
Archivos de cardiologia de Mexico Pub Date : 2024-05-09 DOI: 10.24875/ACM.23000245
Rocío Bautista-Pérez, Óscar Pérez-Méndez, Martha Franco
{"title":"[New concepts in the physiopathology of hypertension. Purinergic receptors].","authors":"Rocío Bautista-Pérez, Óscar Pérez-Méndez, Martha Franco","doi":"10.24875/ACM.23000245","DOIUrl":"10.24875/ACM.23000245","url":null,"abstract":"<p><p>Hypertension is a major risk of morbidity and mortality in patients when it is uncontrolled. In spite of improved therapies currently available for blood pressure control, their complications are far away from being accomplished. Therefore, chronic renal failure is frequently observed in hypertensive patients. Thus, insights on mechanisms that may contribute to arterial pressure control should be studied to prevent life-threatening cardiovascular disorders. Purinergic receptors have been recognized in the physiopathology of hypertension; this review summarizes their participation in the renal abnormalities of the kidney in hypertension. Several studies have suggested the activation of renal purinergic receptors under an elevated interstitial ATP milieu as a fundamental pathway that leads to generation and maintained hypertension. Elevated ATP concentration alters fundamental mechanisms involved in the long-term control of blood pressure such as pressure natriuresis, autoregulation of glomerular filtration rate and renal blood flow, as well as increased tubule-glomerular feedback responses, overall, these alterations decrease sodium excretion; in addition, the expression of ATP receptors is modified. Under a genetical background, ATP induces the production of vasoactive compounds, decreases renal function and induces tubulointerstitial injury before glomerular damage. Simultaneously, a deleterious interaction between angiotensin II and purinergic receptors lead to the progression of renal damage.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":"488-494"},"PeriodicalIF":0.0,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140900630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Undiagnosed arterial hypertension in a Latin American country, 2019 to 2021]. [拉丁美洲某国未确诊的动脉高血压,2019 年至 2021 年]。
Archivos de cardiologia de Mexico Pub Date : 2024-05-09 DOI: 10.24875/ACM.24000026
Julio C Vallejos-Mavila, Rubén Espinoza-Rojas, Jhony A De La Cruz-Vargas
{"title":"[Undiagnosed arterial hypertension in a Latin American country, 2019 to 2021].","authors":"Julio C Vallejos-Mavila, Rubén Espinoza-Rojas, Jhony A De La Cruz-Vargas","doi":"10.24875/ACM.24000026","DOIUrl":"https://doi.org/10.24875/ACM.24000026","url":null,"abstract":"<p><strong>Objective: </strong>To determine the factors associated with undiagnosed hypertension.</p><p><strong>Method: </strong>A quantitative, observational, retrospective, cross-sectional and analytical study was carried out in people aged 15 years and over included in the Demographic and Family Health Survey from 2019 to 2021 in Peru. A statistical analysis was carried out using the corrected F test, and crude and adjusted prevalence ratio (aPR), with a 95% confidence interval (95%CI) for inferential analysis, through Poisson regression with robust variance. Likewise, the CSPLAN analysis was carried out for complex samples according to the sample design and taking into account the weighting factor.</p><p><strong>Results: </strong>In the multivariate analysis, a significant association was found between the factors male sex (aPR: 1.22; 95%CI: 1.19-1.26), age from 30 to 49 years (aPR: 0.94; 95%CI: 0.92-0.96), native ethnicity (aPR: 1.07; 95%CI: 1.04-1.10), having health insurance (aPR: 0.91; 95%CI: 0.89-0.93), suffering from some permanent limitation (aPR: 0.83; 95%CI: 0.76-0.91) and diabetes mellitus (aPR: 0.59; 95%CI: 0.55-0.64). No significant association was found with educational level, language, Afro-Peruvian ethnicity, or alcohol or tobacco consumption (p > 0.05).</p><p><strong>Conclusions: </strong>The prevalence of undiagnosed arterial hypertension is high, 69.5%. The associated factors are male sex, native ethnicity, age between 30 and 49 years, having health insurance, suffering from some permanent limitation and having diabetes mellitus.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140900676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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