Mariel L Foti, Érica V Stelmaszewski, Agustina Del Soldato, Gisela L Páez-Salinas, M Guillermina Soraiz, D Mariela Mouratian
{"title":"[Initial experience with the implementation of an interdisciplinary clinic for the follow-up of pediatric patients with single ventricle].","authors":"Mariel L Foti, Érica V Stelmaszewski, Agustina Del Soldato, Gisela L Páez-Salinas, M Guillermina Soraiz, D Mariela Mouratian","doi":"10.24875/ACM.25000288","DOIUrl":"https://doi.org/10.24875/ACM.25000288","url":null,"abstract":"<p><strong>Background: </strong>Patients with single-ventricle physiology present one of the most complex congenital heart diseases, with implications that extend beyond strictly cardiologic aspects. Survival has improved due to new technologies, but comprehensive, effective, and sustainable follow-up requires innovative care models.</p><p><strong>Objective: </strong>To describe the implementation and outcomes of an interdisciplinary clinic in a high-complexity public hospital in Argentina.</p><p><strong>Method: </strong>This is a retrospective, longitudinal, descriptive study from the initiation of the interdisciplinary clinic in April 2023 through August 2025. A monthly multidisciplinary care setting was established. The strategy included an organized pre-clinic evaluation, sequential clinical consultations, psychoeducational workshops for families, and therapeutic play sessions. A formalized roadmap and interdisciplinary communication structure were implemented.</p><p><strong>Results: </strong>From April 2023 to August 2025, 81 patients were incorporated into this care model. The median age at the time of first surgery was 16 days. Attendance rates for scheduled visits increased from 70 to 92%. Significant improvements were achieved in care coordination, early detection of cardiac and extracardiac complications, access to complementary studies, and adherence to follow-up. More than 60% of families participated in workshops, creating spaces for support and shared experiences.</p><p><strong>Conclusion: </strong>The interdisciplinary single-ventricle clinic at Hospital de Pediatría SAMIC Juan P. Garrahan represents an innovative and unique model in Argentina, with a positive impact on adherence, early identification of complications, and family engagement.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148681480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stephanie D Centellas-Ibáñez, Bernardo J Fernández-Rivera
{"title":"[Anesthesia in carcinoid syndrome for tricuspid and pulmonary valve replacement: case report].","authors":"Stephanie D Centellas-Ibáñez, Bernardo J Fernández-Rivera","doi":"10.24875/ACM.25000250","DOIUrl":"https://doi.org/10.24875/ACM.25000250","url":null,"abstract":"<p><p>Carcinoid syndrome is characterized by the presence of a carcinoid tumor that can release chemical mediators that, if not adequately controlled, can even lead to carcinoid crisis. In this condition occurs hemodynamic instability, with distributive shock, bronchospasm, and cardiac arrhythmias. Carcinoid tumors have an incidence of 1-2 cases per 100,000 patients, and 20-30% of them present episodic vasomotor symptoms such as bronchospasm, hypotension and diarrhea secondary to therelease of vasoactive amines. Because it is an infrequent situation, we present the anesthetic management of a patient withcarcinoid syndrome undergoing surgery for tricuspid and pulmonary valve replacement, where we indicate the procedure forinduction, maintenance and termination of anesthesia without any reported events. The risk of a carcinoid crisis must beconsidered, in conjunction with a multidisciplinary approach to ensure effective surgery.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148681515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A Antonio Montañez-Aguirre, Karina Del Valle Zamora, Alberto Aranda-Fraustro, Silvia Jiménez-Becerra, María L Loredo-Mendoza
{"title":"Intimal sarcoma of the heart and great vessels: clinicopathologic series with imaging and immunohistochemistry correlation.","authors":"A Antonio Montañez-Aguirre, Karina Del Valle Zamora, Alberto Aranda-Fraustro, Silvia Jiménez-Becerra, María L Loredo-Mendoza","doi":"10.24875/ACM.26000025","DOIUrl":"https://doi.org/10.24875/ACM.26000025","url":null,"abstract":"<p><p>Intimal sarcoma (IS) is an extremely rare but aggressive malignant tumor and is now recognized as the most frequent primary malignancy of the heart and great vessels. Its clinical presentation is often non-specific, frequently mimicking common conditions such as pulmonary embolism or cardiac myxoma, leading to significant diagnostic delays. This case series describes four women with IS in various locations: two in the left atrium with mitral valve involvement, one in the main pulmonary artery, and one presenting as a pulmonary mass. Diagnosis relied on multimodal imaging, including echocardiography, computed tomography, and magnetic resonance imaging, followed by histopathological confirmation. Microscopic analysis revealed marked cellular pleomorphism and high mitotic activity. Immunohistochemistry (IHC) was essential for the final diagnosis, as all cases demonstrated nuclear mouse double minute 2 (MDM2) expression, a defining marker associated with gene amplification. Other markers, such as h-caldesmon and diffuse cluster of differentiation 31, were negative, effectively excluding leiomyosarcoma and angiosarcoma. Given its poor prognosis and high embolic potential, early recognition and radical surgical resection remain crucial for patient survival. This series emphasizes the clinical relevance of considering IS in the differential diagnosis of intracardiac and endovascular masses, highlighting MDM2 IHC as a reliable diagnostic tool.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148681502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jose D Bran, Luis A Vélez, Juan C Araque, Sofía Vélez
{"title":"Floating aortic arch thrombus revealing an occult ascending aortic dissection: a case report.","authors":"Jose D Bran, Luis A Vélez, Juan C Araque, Sofía Vélez","doi":"10.24875/ACM.26000029","DOIUrl":"https://doi.org/10.24875/ACM.26000029","url":null,"abstract":"<p><p>Floating thrombus of the thoracic aorta is an uncommon but potentially catastrophic source of systemic embolization. Although most cases are associated with structural abnormalities of the aortic wall, pre-operative imaging may occasionally suggest an isolated intraluminal thrombus, with the underlying pathology becoming evident only during surgical exploration. We report the case of a 49-year-old woman with active tobacco use who presented with progressive pain and dysesthesia of the left upper limb and was diagnosed with brachial artery thrombosis. Computed tomography angiography revealed an intraluminal thrombus within the aortic arch, while echocardiography showed a large, highly mobile pedunculated mass attached to the lesser curvature. Given the high risk of recurrent embolization, urgent surgical intervention was performed. Intraoperative inspection identified a giant floating thrombus measuring approximately 8 cm. Further exploration revealed an ulcerated lesion with a contained dissection of the ascending aorta, considered the likely nidus for thrombus formation. The thrombus was removed, and the affected ascending aortic segment was resected and reconstructed using a supracoronary Dacron graft. The post-operative course was uneventful, and the patient was discharged on oral anticoagulation. This case highlights a key diagnostic limitation of pre-operative imaging and supports surgical exploration as both a diagnostic and therapeutic strategy in selected high-risk patients.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148474631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lyda Z Rojas, Laura V Arciniegas-Landinez, Angie Y Serrano-García, Angela Torres-Bustamante, Karen García-Rueda, Jaime Rodríguez, Sergio A Gómez-Ochoa, Luis E Echeverria
{"title":"Mortality risk stratification in acute decompensated heart failure: ICARUS score for four-pillar era.","authors":"Lyda Z Rojas, Laura V Arciniegas-Landinez, Angie Y Serrano-García, Angela Torres-Bustamante, Karen García-Rueda, Jaime Rodríguez, Sergio A Gómez-Ochoa, Luis E Echeverria","doi":"10.24875/ACM.26000022","DOIUrl":"https://doi.org/10.24875/ACM.26000022","url":null,"abstract":"<p><strong>Background: </strong>Acute decompensated heart failure (ADHF) remains a leading cause of hospitalization and short-term death despite quadruple guideline-directed therapy. Early, pragmatic risk stratification at admission is essential.</p><p><strong>Objective: </strong>To identify independent predictors of in-hospital mortality in ADHF within the four-pillar era and to derive a simple bedside score (ICARUS).</p><p><strong>Methods: </strong>A retrospective cohort study was conducted of hospitalized adults, consecutively selected, with acute decompensated heart failure (de novo or chronic). Pre-specified candidate predictors were categorized with clinically informed cutoff and entered into multivariable logistic regression (backward selection). Model fit and discrimination were assessed using the Hosmer-Lemeshow test and the area under the receiver operating characteristic curve (area under the curve [AUC]), respectively. Coefficients were scaled to create a points-based score.</p><p><strong>Results: </strong>Among 1588 patients (median age 68 years; 69.3% male; median left ventricular ejection fraction [LVEF] 30%), in-hospital mortality was 4.28% (68/1,588; 95% confidence interval [CI] 3.34-5.39). Independent risk factors were diabetes (odds ratio [OR] 1.81), the New York Heart Association III-IV (OR: 1.97), the Minnesota Living with Heart Failure Questionnaire ≥ 41 (OR: 2.09), atrial fibrillation (OR: 2.29), hyperkalemia K+ > 5.5 mmol/L (OR: 2.63), and systolic blood pressure ≤ 110 mmHg (OR: 3.14). Protective factors were β-blocker use at admission (OR: 0.38), implantable device (OR: 0.22), and in-hospital sodium-glucose cotransporter 2 inhibitor therapy (OR: 0.27). The model showed good model fit (Hosmer-Lemeshow p = 0.997) and strong discriminative ability (AUC 0.81). The ICARUS points system performed similarly (AUC: 0.792; 95% CI 0.738-0.845), with stepwise increases in mortality across strata.</p><p><strong>Conclusion: </strong>Nine readily obtainable variables accurately stratified in-hospital mortality risk in ADHF. The ICARUS score is a pragmatic bedside tool, integrating clinical status and modern therapy, with a good goodness-of-fit and discrimination.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148474584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dafne M Macías-Argüelles, Germán R Bautista-López, Hilda E Macías-Cervantes, José M Sánchez-López, Mario A Castillo-Velázquez, Marco A Solórzano-Vázquez, Juan A Cibrián-Delgado, Edgar U Quintana-Ortiz, Enrique A Bernal-Ruíz, Luis M Vargas-Ramírez
{"title":"[Jailed balloon versus provisional stenting with drug-coated balloon in true bifurcation lesions].","authors":"Dafne M Macías-Argüelles, Germán R Bautista-López, Hilda E Macías-Cervantes, José M Sánchez-López, Mario A Castillo-Velázquez, Marco A Solórzano-Vázquez, Juan A Cibrián-Delgado, Edgar U Quintana-Ortiz, Enrique A Bernal-Ruíz, Luis M Vargas-Ramírez","doi":"10.24875/ACM.25000223","DOIUrl":"https://doi.org/10.24875/ACM.25000223","url":null,"abstract":"<p><strong>Background: </strong>Coronary bifurcation lesions remain a major challenge in percutaneous coronary intervention because of the risk of side branch compromise or occlusion. Several strategies, including provisional stenting, jailed balloon protection, and drug-coated balloons, have been developed to preserve side branch patency; however, direct comparative evidence in true bifurcation lesions remains limited.</p><p><strong>Objective: </strong>To determine the frequency of side branch compromise in coronary bifurcation lesions treated with jailed balloon technique versus provisional stenting plus drug-coated balloon.</p><p><strong>Method: </strong>Open-label randomized clinical trial conducted at UMAE No. 1 Bajío, IMSS, from April to September 2025. A total of 32 patients with acute or chronic coronary syndrome and true bifurcation lesions (Medina 1-1-1, 1-0-1, 0-1-1) were randomized 1:1 to provisional stenting with drug-coated balloon or jailed balloon. The primary endpoint was side branch compromise (occlusion, > 90% ostial pinching, or dissection > A). Clinical, angiographic, and procedural outcomes were analyzed.</p><p><strong>Results: </strong>Sixteen patients were allocated to each technique. Baseline characteristics were similar. Both strategies achieved universal angiographic success (TIMI 3 flow in all cases). Conversion to two stents was infrequent (three cases). Contrast use per treated vessel was significantly lower with the jailed balloon technique (56.7 vs 115.0 ml; p = 0.0016). No major adverse events were reported during early follow-up.</p><p><strong>Conclusions: </strong>Both strategies proved safe and effective for true bifurcation lesions, even in high-risk patients. The jailed balloon technique offered the additional advantage of significantly reducing contrast use, which may be especially beneficial in patients at risk of contrast-induced nephropathy.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148474595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eloísa B S Puch-Kú, Anahí Juárez-Morales, Sandra S Mena-Carrillo, Alex A Hau-Moo, Ligia M Rosado-Alcocer, Julia A Cándila-Celis
{"title":"[Lung expansion exercises].","authors":"Eloísa B S Puch-Kú, Anahí Juárez-Morales, Sandra S Mena-Carrillo, Alex A Hau-Moo, Ligia M Rosado-Alcocer, Julia A Cándila-Celis","doi":"10.24875/ACM.25000295","DOIUrl":"https://doi.org/10.24875/ACM.25000295","url":null,"abstract":"<p><p>The objective was to analyze the effect of pulmonary expansion exercises on pulmonary functional capacity in patients undergoing cardiac surgery. An integrative review with a quantitative approach was conducted, structured based on methodological principles of PRISMA 2020. The research question was formulated using the PIO framework. The literature search was performed in PubMed, BVS, Journal of PeriAnesthesia Nursing, Epistemonikos, SciELO, ScienceDirect, and EBSCO, using DeCS and MeSH terms combined with Boolean operators. A total of 45 potentially relevant studies were identified, of which 12 met the inclusion criteria, incorporating both primary studies and systematic reviews. Methodological quality was assessed using the FLC instrument version 3.0 and the Oxford Centre for Evidence-Based Medicine classification. Risk of bias was evaluated according to study design, using RoB 2 for randomized controlled trials and ROBIS for systematic reviews. The synthesis considered comparisons across levels of evidence to minimize potential duplication of results. Findings suggest that inspiratory muscle training is associated with improvements in respiratory muscle strength, pulmonary function, and functional capacity. Additionally, the use of volume-oriented incentive spirometry, particularly when guided by nursing staff, is associated with favorable pulmonary outcomes in the postoperative period.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148474598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jhonathan Uribe-González, Erick Trujillo-Virgen, Daniela Leocachín-Parra, Silvestre Montoya-Guerrero, Horacio Márquez-González, Agustín Campuzano-Madrid, Efraín Arizmendi-Uribe, Eileen Amaro-Balderas, Daniel Campuzano-González, Joel Estrada-Gallegos
{"title":"Outcomes of thoracic endovascular aortic repair. 10-years follow-up in LATAM population: experience from a tertiary care center in Mexico.","authors":"Jhonathan Uribe-González, Erick Trujillo-Virgen, Daniela Leocachín-Parra, Silvestre Montoya-Guerrero, Horacio Márquez-González, Agustín Campuzano-Madrid, Efraín Arizmendi-Uribe, Eileen Amaro-Balderas, Daniel Campuzano-González, Joel Estrada-Gallegos","doi":"10.24875/ACM.25000084","DOIUrl":"https://doi.org/10.24875/ACM.25000084","url":null,"abstract":"<p><strong>Background: </strong>Thoracic aortic pathologies comprise a broad group of conditions affecting one or more layers of the aorta, some of which are known to be life-threatening. The development of thoracic aortic endovascular repair (TEVAR) has enabled a minimally invasive approach for treating these cases, with excellent long-term results.</p><p><strong>Objective: </strong>To describe clinical and technical outcomes of patients who underwent thoracic endovascular aortic repair (TEVAR) in a single tertiary care center.</p><p><strong>Method: </strong>An observational, descriptive, retrospective cohort study. We included patients of 18 years-old or older who underwent TEVAR either as a single procedure or as part of a hybrid repair, between 2011 and 2023, in the Cardiology Hospital of the National Medical Centre XXI Century.</p><p><strong>Results: </strong>A total of 66 patients were included, of whom 77.2% were men. The most frequent cardiovascular risk factors were hypertension and tobacco use. TEVAR was performed as a single procedure in 57.6% (n = 38) and as a hybrid repair in 42.4% (n = 28). Technical success was achieved in 95.4% (n = 63). Event-free survival was 81.8% (n = 54) during hospitalization, 81.5% (n = 54) at 30 days, 76.9% (n = 50) at 1 year, 75.4% (n = 43) at 5 years, and 63.6% (n = 21) at 10 years. Adverse events occurred in 27.2% (n = 18) of cases, most commonly vascular access complications (12.1%, n = 8), spinal cord ischemia (4.5%, n = 3), and reintervention (4.5%, n = 3).</p><p><strong>Conclusion: </strong>In this retrospective single-center experience, TEVAR demonstrated high technical success and acceptable mid- and long-term event-free survival. These findings support the feasibility and effectiveness of TEVAR in a tertiary-level care setting.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148474826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eloísa B S Puch-Kú, Anahí Juárez-Morales, Sandra S Mena-Carrillo, Alex A Hau-Moo, Ligia M Rosado-Alcocer, Julia A Cándila-Celis
{"title":"[Lung expansion exercises: improve lung function capacity in the postoperative period following cardiac surgery].","authors":"Eloísa B S Puch-Kú, Anahí Juárez-Morales, Sandra S Mena-Carrillo, Alex A Hau-Moo, Ligia M Rosado-Alcocer, Julia A Cándila-Celis","doi":"10.24875/ACM.25000295","DOIUrl":"https://doi.org/10.24875/ACM.25000295","url":null,"abstract":"<p><p>The objective was to analyze the effect of pulmonary expansion exercises on pulmonary functional capacity in patients undergoing cardiac surgery. An integrative review with a quantitative approach was conducted, structured based on methodological principles of PRISMA 2020. The research question was formulated using the PIO framework. The literature search was performed in PubMed, BVS, Journal of PeriAnesthesia Nursing, Epistemonikos, SciELO, ScienceDirect, and EBSCO, using DeCS and MeSH terms combined with Boolean operators. A total of 45 potentially relevant studies were identified, of which 12 met the inclusion criteria, incorporating both primary studies and systematic reviews. Methodological quality was assessed using the FLC instrument version 3.0 and the Oxford Centre for Evidence-Based Medicine classification. Risk of bias was evaluated according to study design, using RoB 2 for randomized controlled trials and ROBIS for systematic reviews. The synthesis considered comparisons across levels of evidence to minimize potential duplication of results. Findings suggest that inspiratory muscle training is associated with improvements in respiratory muscle strength, pulmonary function, and functional capacity. Additionally, the use of volume-oriented incentive spirometry, particularly when guided by nursing staff, is associated with favorable pulmonary outcomes in the postoperative period.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148474611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Olga C Maza-Caneva, Ricardo A Villa-Vargas, Andrea C Restrepo-Hincapié, Carmen M De la Rosa-Villalba, María C Sanjuanelo-Patiño
{"title":"[Diagnostic and therapeutic challenges in pediatric takotsubo syndrome: a case report].","authors":"Olga C Maza-Caneva, Ricardo A Villa-Vargas, Andrea C Restrepo-Hincapié, Carmen M De la Rosa-Villalba, María C Sanjuanelo-Patiño","doi":"10.24875/ACM.25000310","DOIUrl":"https://doi.org/10.24875/ACM.25000310","url":null,"abstract":"<p><p>Takotsubo syndrome is a transient cardiomyopathy that is uncommon in pediatric patients, characterized by acute left ventricular dysfunction and regional wall motion abnormalities in the absence of obstructive coronary artery disease. Its recognition in children remains challenging because of its low incidence and its overlap with other causes of hemodynamic deterioration, particularly in the postoperative cardiovascular setting. We report the case of a 15-year-old adolescent with Barlow syndrome and severe mitral regurgitation who underwent mechanical mitral valve replacement. During the procedure, findings suggestive of endocarditis were identified and subsequently confirmed by isolation of Serratia marcescens. On postoperative day 4, the patient developed hemodynamic deterioration requiring vasoactive support, with moderate elevation of cardiac biomarkers and an echocardiographic pattern consistent with takotsubo syndrome, characterized by apical and midventricular akinesia, compensatory basal hypercontractility, and a left ventricular ejection fraction of 35%. Given the limited response to catecholamines, levosimendan was administered, with progressive clinical improvement. In the third postoperative week, cardiac magnetic resonance imaging ruled out myocarditis and demonstrated in-hospital functional recovery. This case highlights the importance of considering takotsubo syndrome in the differential diagnosis of postoperative hemodynamic deterioration in pediatric patients, particularly when echocardiography reveals typical segmental abnormalities that allow early diagnostic suspicion and timely management.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148474870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}