Archivos de cardiologia de Mexico最新文献

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[Closure of patent ductus arteriosus with OcclutechTM device, experience in an andean country]. [用 OcclutechTM 装置闭合动脉导管未闭,一个安第斯国家的经验]。
Archivos de cardiologia de Mexico Pub Date : 2024-02-15 DOI: 10.24875/ACM.23000126
Raúl E Ríos-Méndez, María E Araúz-Martínez, Jorge A Oliveros-Rivero, Yeiber J Crespo-Gutiérrez, Yesenia W Pérez-Vite
{"title":"[Closure of patent ductus arteriosus with Occlutech<sup>TM</sup> device, experience in an andean country].","authors":"Raúl E Ríos-Méndez, María E Araúz-Martínez, Jorge A Oliveros-Rivero, Yeiber J Crespo-Gutiérrez, Yesenia W Pérez-Vite","doi":"10.24875/ACM.23000126","DOIUrl":"10.24875/ACM.23000126","url":null,"abstract":"<p><strong>Background and objective: </strong>To communicate the experience in an Andean country with the OcclutechTM Duct Occluder device for the closure of patent ductus arteriosus.</p><p><strong>Method: </strong>observational, retrospective, cross-sectional study with basic statistical analysis. Period: December/2014 to December/2022. Data: medical chart, reports of catheterization.</p><p><strong>Results: </strong>Forty-six patients, female 71.3%, male 28.7%; age: 0.6-38 years-old (median [Me]: 5.2); weight: 6.3-60 kg (Me: 16.5). Origin: Andean 91.3%, coast 8.7%. Types of patent ductus arteriosus: E 54.4%, A 32.6%, D 13%. Minimum ductal diameter: 1.8-11.8 mm (Me: 3.5). Mean pulmonary artery pressure prior to occlusion: 14-67 mmHg (Me: 27). Pulmonary vascular resistance index prior to occlusion: 0.28-4.9 WU/m2 (Me: 1.3). Six of them were classified as hypertensive patent ductus arteriosus. Occlusion rate: 47.8% immediate, 81% at 24 hours, 100% after six months. Fluoroscopy time: 2-13.8 minutes (Me: 4). Complications: a migrated device. Follow-up: 1-6.5 years.</p><p><strong>Conclusions: </strong>Occlutech<sup>TM</sup> Duct Occluder device was effective and safe for the closure of patent ductus arteriosus type E, A and D in low-altitude and high-altitude dwellers, whether they were children or adults, even when these ductus arteriosus were hypertensive.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":"169-173"},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11160539/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139742910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Translational research: from the laboratory bench to the patient's bedside. Congenital heart disease: a window to knowledge]. [转化研究:从实验室工作台到病人床边。先天性心脏病:知识之窗]。
Archivos de cardiologia de Mexico Pub Date : 2024-02-15 DOI: 10.24875/ACM.23000125
Juan Calderón-Colmenero, Diego B Ortega-Zhindón, Nonanzit Pérez-Hernández, José M Rodríguez-Pérez, Jorge L Cervantes-Salazar
{"title":"[Translational research: from the laboratory bench to the patient's bedside. Congenital heart disease: a window to knowledge].","authors":"Juan Calderón-Colmenero, Diego B Ortega-Zhindón, Nonanzit Pérez-Hernández, José M Rodríguez-Pérez, Jorge L Cervantes-Salazar","doi":"10.24875/ACM.23000125","DOIUrl":"10.24875/ACM.23000125","url":null,"abstract":"","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":"258-260"},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11160554/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139742914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The current state of renal sympathetic denervation in hypertension]. [高血压肾交感神经去神经化的现状]。
Archivos de cardiologia de Mexico Pub Date : 2024-02-15 DOI: 10.24875/ACM.23000191
Jaime A Gómez-Rosero, Laura Duque-González, Juan M Senior-Sánchez
{"title":"[The current state of renal sympathetic denervation in hypertension].","authors":"Jaime A Gómez-Rosero, Laura Duque-González, Juan M Senior-Sánchez","doi":"10.24875/ACM.23000191","DOIUrl":"10.24875/ACM.23000191","url":null,"abstract":"<p><p>This review provides an overview of the efficacy and safety of renal sympathetic denervation as a therapeutic approach for resistant hypertension. While the initial enthusiasm was sparked by the results of early clinical trials, it was dampened by the findings of the Symplicity HTN-3 study. However, recent advances in catheter technology and more refined patient selection criteria have yielded more promising results. Subsequent studies, such as SPYRAL HTN-OFF MED and RADIANCE II, demonstrated significant reductions in blood pressure, even in patients with mild to moderate hypertension. Despite the lack of robust data on major clinical outcomes, investigations into the time in therapeutic range for patients undergoing renal sympathetic denervation suggested potential cardiovascular benefits. Nevertheless, further research is needed to thoroughly understand the long-term impact, assess cost-effectiveness, and accurately identify which patient subgroups may derive the greatest benefits from this therapy.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":"366-372"},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11259422/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139742913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Impact of diabetes on cardiovascular risk in patients with dyslipidemia]. [糖尿病对血脂异常患者心血管风险的影响]。
Archivos de cardiologia de Mexico Pub Date : 2024-02-12 DOI: 10.24875/ACM.23000042
Gregorio Peña-Rodríguez, Ana G Gallardo-Hernández, Cindy G Llerena-García, Martha A Maldonado-Burgos, Eloísa Escobedo-Naurisa
{"title":"[Impact of diabetes on cardiovascular risk in patients with dyslipidemia].","authors":"Gregorio Peña-Rodríguez, Ana G Gallardo-Hernández, Cindy G Llerena-García, Martha A Maldonado-Burgos, Eloísa Escobedo-Naurisa","doi":"10.24875/ACM.23000042","DOIUrl":"10.24875/ACM.23000042","url":null,"abstract":"<p><strong>Objective: </strong>To determine the impact of diabetes on cardiovascular risk in patients with dyslipidemia.</p><p><strong>Method: </strong>Observational, cross-sectional and comparative study in which cardiovascular risk was determined at 10 years in 100 patients with dyslipidemia, of these, 50 non-diabetic patients and 50 diabetic patients.</p><p><strong>Results: </strong>Both groups had similar characteristics in terms of age, blood pressure figures, average body mass index, and HDL and LDL levels. It was observed that the diabetic group has almost double the risk compared to the dyslipidemia group, 13.7 vs. 7.9 (p = 0.014), and the calculated heart age is also higher in patients with diabetes, 80 vs. 66 years (p = 0.003). Even in patients with diabetes there is a greater difference between the real age and the age of the heart, 24 years vs. 15 years of patients without diabetes (p = 0.000).</p><p><strong>Conclusion: </strong>Having diabetes and dyslipidemia doubles the cardiovascular risk of patients. Little metabolic control was found in the population studied, which significantly increases complications at an early age and the economic burden on the health system and the families of patients, so it is necessary to rethink treatment strategies to improve metabolic control and with it the prognosis for the patient in the long term.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":"161-168"},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11160545/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139725317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[First experience in Mexico with plasmapheresis and rituximab treating humoral rejection in heart transplant]. [在墨西哥首次使用血浆置换和利妥昔单抗治疗心脏移植中的体液排斥反应]。
Archivos de cardiologia de Mexico Pub Date : 2024-02-08 DOI: 10.24875/ACM.23000149
Gustavo Inzunza-Cervantes, José A Cigarroa-Lopéz, Antonio Tepayotl-Aponte, Raúl Martínez-Castro, José A Magaña-Serrano, Juan B Ivey-Miranda
{"title":"[First experience in Mexico with plasmapheresis and rituximab treating humoral rejection in heart transplant].","authors":"Gustavo Inzunza-Cervantes, José A Cigarroa-Lopéz, Antonio Tepayotl-Aponte, Raúl Martínez-Castro, José A Magaña-Serrano, Juan B Ivey-Miranda","doi":"10.24875/ACM.23000149","DOIUrl":"10.24875/ACM.23000149","url":null,"abstract":"","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":"247-250"},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11160553/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139708738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Happy heart syndrome, a rare variant of takotsubo cardiomyopathy: a case report]. [快乐心综合征--一种罕见的拓扑心肌病变体:病例报告]。
Archivos de cardiologia de Mexico Pub Date : 2024-02-08 DOI: 10.24875/ACM.23000013
Ulises Gómez-Álvarez, Denisse A Razo-Ortega, Amada Álvarez-Sangabriel, Juan C de la Fuente-Mancera, Carlos A Guizar-Sánchez
{"title":"[Happy heart syndrome, a rare variant of <i>takotsubo</i> cardiomyopathy: a case report].","authors":"Ulises Gómez-Álvarez, Denisse A Razo-Ortega, Amada Álvarez-Sangabriel, Juan C de la Fuente-Mancera, Carlos A Guizar-Sánchez","doi":"10.24875/ACM.23000013","DOIUrl":"10.24875/ACM.23000013","url":null,"abstract":"","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":"243-246"},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11160537/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139708739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Left ventricular hypertrophy: hypertensive or hypertrophic cardiomyopathy? What a dilemma! A case report. 左心室肥厚:高血压还是肥厚性心肌病?真是进退两难!病例报告。
Archivos de cardiologia de Mexico Pub Date : 2024-02-08 DOI: 10.24875/ACM.23000063
Albina Aldomà-Balasch, Marta Z Zielonka, Pedro K Rivera-Aguilar, Ramón Bascompte-Claret
{"title":"Left ventricular hypertrophy: hypertensive or hypertrophic cardiomyopathy? What a dilemma! A case report.","authors":"Albina Aldomà-Balasch, Marta Z Zielonka, Pedro K Rivera-Aguilar, Ramón Bascompte-Claret","doi":"10.24875/ACM.23000063","DOIUrl":"10.24875/ACM.23000063","url":null,"abstract":"<p><p>In the presence of the left ventricle hypertrophy (LVH), the differential diagnosis with hypertrophic cardiomyopathy (HCM) or some phenocopy must be always considered, which can be easily suspected when the hypertrophy is markedly asymmetric. However, when the hypertrophy is homogeneous, especially if the patient has concomitant hypertension, it may be a challenge to distinguish between hypertensive and HCM, although some clinical features may help us to suspect it. In addition, patients with HCM may present with exertional angina due to microcirculation involvement in the setting of the hypertrophy itself or dynamic obstruction in the left ventricular outflow tract, but in some cases, the presence of concomitant coronary artery disease must be suspected as the cause of angina, especially if the patient has an intermediate or high-risk probability of having ischemic heart disease. We present the case of a 46-year-old Afro-American man with poorly controlled hypertension who was found to have severe LVH, and who presented with symptoms of exertional angina during follow-up. We will review the clinical features that can help us in the differential diagnosis in this context.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":"203-207"},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11160542/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139708741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Phosphodiesterase 5 inhibitors for the treatment of heart failure: a systematic review and meta-analysis]. [治疗心力衰竭的磷酸二酯酶 5 抑制剂:系统回顾和荟萃分析]。
Archivos de cardiologia de Mexico Pub Date : 2024-02-08 DOI: 10.24875/ACM.23000209
Ramiro Monzón-Herrera, Federico Listorti, Natalia Vensentini, Javier Mariani
{"title":"[Phosphodiesterase 5 inhibitors for the treatment of heart failure: a systematic review and meta-analysis].","authors":"Ramiro Monzón-Herrera, Federico Listorti, Natalia Vensentini, Javier Mariani","doi":"10.24875/ACM.23000209","DOIUrl":"10.24875/ACM.23000209","url":null,"abstract":"<p><strong>Objective: </strong>The treatment with phosphodiesterase-5 (PDE-5) inhibitors was postulated in heart failure (HF). We conducted a systematic review and a meta-analysis on their beneficial and adverse effects in patients with HF.</p><p><strong>Method: </strong>A meta-analysis of randomized trials evaluating the chronic use of PDE-5 inhibitors in patients with HF was conducted. Endpoints included death, HF hospitalizations, functional capacity, pulmonary pressures, quality of life, and adverse effects. Random-effects models were used to pool outcomes. Categorical data were summarized with relative risks (RR) and 95% confidence intervals (95%CI), and continuous data with weighted mean differences and standardized mean differences.</p><p><strong>Results: </strong>Sixteen studies (1119 participants) were included. No effect was observed on mortality (RR: 1.16; 95%CI: 0.50-2.66; I2: 0.0%) or HF hospitalizations (RR: 0.75; 95%CI: 0.41-1.37; I2: 38.7%). Treatment significantly reduced pulmonary systolic pressure (-10.64 mmHg; 95%CI: -5.14 to -16.15 mmHg; I2: 96.0%), and increased peak oxygen consumption (2.06 ml/kg/min; 95%CI: 0.40-3.72; I2: 89.6%), although with high inconsistency. There were no significant effects on quality of life (-0.15; 95%CI: -0.48-0.18; I2: 0.0%). On the other hand, the risk of headaches was increased (RR: 1.63; 95%CI: 1.11-2.39; I2: 0.0%). Publication bias was identified for HF hospitalizations.</p><p><strong>Conclusions: </strong>Current data suggest that PDE-5 inhibitors therapy does not improve prognosis or quality of life among HF patients. Hemodynamic and functional effects could be relevant, and more studies are necessary to define its role.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":"309-323"},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11259423/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139708740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Summary: International consensus statement on nomenclature and classification of the congenital bicuspid aortic valve and its aortopathy, for clinical, surgical, interventional and research purposes]. [摘要:关于先天性双尖瓣及其主动脉病变的命名和分类的国际共识声明,用于临床、手术、介入和研究目的]。
Archivos de cardiologia de Mexico Pub Date : 2024-02-07 DOI: 10.24875/ACM.24000002
Hector I Michelena, Alessandro Della Corte, Arturo Evangelista, Joseph J Maleszewski, William D Edwards, Mary J Roman, Richard B Devereux, Borja Fernández, Federico M Asch, Alex J Barker, Lilia M Sierra, Laurent de Kerchove, Susan M Fernandes, Paul W M Fedak, Evaldas Girdauskas, Victoria Delgado, Suhny Abbara, Emmanuel Lansac, Siddharth K Prakash, Malenka M Bissell, Bogdan A Popescu, Michael D Hope, Marta Sitges, Vinod H Thourani, Phillippe Pibarot, Krishnaswamy Chandrasekaran, Patrizio Lancellotti, Michael A Borger, John K Forrest, John Webb, Dianna M Milewicz, Raj Makkar, Martin B Leon, Stephen P Sanders, Michael Markl, Victor A Ferrari, William C Roberts, Jae-Kwan Song, Philipp Blanke, Charles S White, Samuel Siu, Lars G Svensson, Alan C Braverman, Joseph Bavaria, Thoralf M Sundt, Gebrine El Khoury, Ruggero de Paulis, Maurice Enriquez-Sarano, Jeroen J Bax, Catherine M Otto, Hans-Joachim Schäfers
{"title":"[Summary: International consensus statement on nomenclature and classification of the congenital bicuspid aortic valve and its aortopathy, for clinical, surgical, interventional and research purposes].","authors":"Hector I Michelena, Alessandro Della Corte, Arturo Evangelista, Joseph J Maleszewski, William D Edwards, Mary J Roman, Richard B Devereux, Borja Fernández, Federico M Asch, Alex J Barker, Lilia M Sierra, Laurent de Kerchove, Susan M Fernandes, Paul W M Fedak, Evaldas Girdauskas, Victoria Delgado, Suhny Abbara, Emmanuel Lansac, Siddharth K Prakash, Malenka M Bissell, Bogdan A Popescu, Michael D Hope, Marta Sitges, Vinod H Thourani, Phillippe Pibarot, Krishnaswamy Chandrasekaran, Patrizio Lancellotti, Michael A Borger, John K Forrest, John Webb, Dianna M Milewicz, Raj Makkar, Martin B Leon, Stephen P Sanders, Michael Markl, Victor A Ferrari, William C Roberts, Jae-Kwan Song, Philipp Blanke, Charles S White, Samuel Siu, Lars G Svensson, Alan C Braverman, Joseph Bavaria, Thoralf M Sundt, Gebrine El Khoury, Ruggero de Paulis, Maurice Enriquez-Sarano, Jeroen J Bax, Catherine M Otto, Hans-Joachim Schäfers","doi":"10.24875/ACM.24000002","DOIUrl":"10.24875/ACM.24000002","url":null,"abstract":"<p><p>This consensus of nomenclature and classification for congenital bicuspid aortic valve and its aortopathy is evidence-based and intended for universal use by physicians (both pediatricians and adults), echocardiographers, advanced cardiovascular imaging specialists, interventional cardiologists, cardiovascular surgeons, pathologists, geneticists, and researchers spanning these areas of clinical and basic research. In addition, as long as new key and reference research is available, this international consensus may be subject to change based on evidence-based data1.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":"219-239"},"PeriodicalIF":0.0,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11160548/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139704241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Increased risk of bleeding in patients with atrial fibrillation and chronic kidney disease on hemodialysis treated with anticoagulants. A four center serie]. [使用抗凝剂进行血液透析的心房颤动和慢性肾病患者的出血风险增加。四个中心的研究]。
Archivos de cardiologia de Mexico Pub Date : 2024-02-07 DOI: 10.24875/ACM.23000006
Laura V López-Gutiérrez, María I Mora-Atehortúa, Sebastián Peláez-García, Fabián A Jaimes-Barragán, Yesid A Saavedra-González, Diego A Ossa-Estrada, Juan P Villegas-Molina, Andrés H Polo-Guzmán, Clara I Saldarriaga-Giraldo
{"title":"[Increased risk of bleeding in patients with atrial fibrillation and chronic kidney disease on hemodialysis treated with anticoagulants. A four center serie].","authors":"Laura V López-Gutiérrez, María I Mora-Atehortúa, Sebastián Peláez-García, Fabián A Jaimes-Barragán, Yesid A Saavedra-González, Diego A Ossa-Estrada, Juan P Villegas-Molina, Andrés H Polo-Guzmán, Clara I Saldarriaga-Giraldo","doi":"10.24875/ACM.23000006","DOIUrl":"10.24875/ACM.23000006","url":null,"abstract":"<p><strong>Background: </strong>Because the benefits and risks of anticoagulation are still unknown in patients with atrial fibrillation (AF) and with chronic kidney disease (CKD) on hemodialysis.</p><p><strong>Objective: </strong>The aim of this study was to estimate whether the consumption of anticoagulants was associated with a difference in the frequency of thrombosis of any site, major bleeding and mortality, in adults with both diseases.</p><p><strong>Method: </strong>A retrospective cohort study was carried out in four high complexity centers. Patients older than 18 years with CKD on hemodialysis and non-valvular AF, with an indication for anticoagulation (CHA2DS-2VASc ≥ 2), were included. The primary outcome was the occurrence of: major bleeding, thrombotic event (cerebrovascular accident, acute myocardial infarction or venous thromboembolic disease) or death. Adjustment for confounding variables was performed using logistic regression.</p><p><strong>Results: </strong>From 158 patients included, 61% (n = 97) received an anticoagulant. The main outcome was found in 84% of those who received anticoagulation and 70% of those who did not (OR: 2.12, 95%CI: 0.98-4.57; after the adjusted analysis OR: 2.13, 95%CI: 1.04-4.36). Separate outcomes were bleeding in 52% vs. 34% (OR: 2.03; 95%CI: 1.05-3.93), thrombosis in 35% vs. 34% (OR: 1.03; 95%CI: 0.52-2-01) and death in 46% vs 41% (OR: 1.25; 95%CI: 0.65-2.38).</p><p><strong>Conclusions: </strong>The results of this study suggest an increased risk of bleeding in patients with AF and CKD on hemodialysis receiving anticoagulation, without a decrease in the risk of thrombotic events or all-cause mortality.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":" ","pages":"151-160"},"PeriodicalIF":0.0,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11160555/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139704240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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