Brain Circulation最新文献

{"title":"Erratum: Compromised dynamic cerebral autoregulation is a hemodynamic marker for predicting poor prognosis even with good recanalization after endovascular thrombectomy.","authors":"","doi":"10.4103/BC.BC_60_24","DOIUrl":"10.4103/BC.BC_60_24","url":null,"abstract":"<p><p>[This corrects the article on p. 77 in vol. 10, PMID: 38655440.].</p>","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"10 2","pages":"192"},"PeriodicalIF":2.3,"publicationDate":"2024-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11259323/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141733561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unraveling belly dancer's dyskinesia and other puzzling diagnostic contortions: A narrative literature review.","authors":"Jamir Pitton Rissardo, Nilofar Murtaza Vora, Irra Tariq, Vanshika Batra, Ana Letícia Fornari Caprara","doi":"10.4103/bc.bc_110_23","DOIUrl":"10.4103/bc.bc_110_23","url":null,"abstract":"<p><p>Belly dancer's dyskinesia (BDD) is characterized by involuntary abdominal wall movements that are rhythmic, repetitive, and dyskinetic. The present study aims to review BDD's etiology, pathophysiology, and management. We searched six databases to locate existing reports on BDD published from 1990 to October 2023 in electronic form. A total of 47 articles containing 59 cases were found. The majority of the patients affected by BDD were female, accounting for 61.01% (36/59) of the cases. The mean and median ages were 49.8 (standard deviation: 21.85) and 52 years (range: 7-85), respectively. The BDD was unilateral in only 3.38% (2/59). The most commonly reported causes associated with BDD were 17 idiopathic, 11 drug-induced, 11 postsurgical procedures, 5 pregnancies, and 4 Vitamin B12 deficiencies. BDD is a diagnosis of exclusion, and other more common pathologies with similar presentation should be ruled out initially. Differential diagnostic reasoning should include diaphragmatic myoclonus, cardiac conditions, truncal dystonia, abdominal motor seizures, propriospinal myoclonus, and functional or psychiatric disorders.</p>","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"10 2","pages":"106-118"},"PeriodicalIF":2.3,"publicationDate":"2024-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11259329/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141736332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary antiphospholipid syndrome in the elderly: Four strokes and mechanical thrombectomies until the diagnosis - A case report.","authors":"Anatoli Anastasiadi, Chiara Bott, Daniel Kitterer, Elke Roser, Hans Henkes, Hansjörg Bäzner, Marc E Wolf","doi":"10.4103/bc.bc_67_23","DOIUrl":"10.4103/bc.bc_67_23","url":null,"abstract":"<p><p>Antiphospholipid syndrome (APS) is known as a rare etiology of embolic ischemic stroke. In individuals below 50 years, up to 20% of strokes are associated with APS, whereas in patients >50 years, it is considered a very seldom cause of stroke. We describe the course of a 66-year-old white woman, who experienced four embolic strokes with large vessel occlusion over a period of 2 years, which were repeatedly and successfully treated by mechanical thrombectomy. Initially attributed to atrial fibrillation and treated with direct oral anticoagulants, the patient was finally diagnosed with primary APS due to isolated anti-beta 2-glycoprotein antibodies and successfully treated after several stroke recurrences. After initiation of Vitamin K antagonist therapy, no further strokes occurred. For recurrent embolic stroke despite oral anticoagulation, late-onset APS might be considered a rare etiology also in the elderly.</p>","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"10 2","pages":"184-187"},"PeriodicalIF":2.3,"publicationDate":"2024-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11259320/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141733562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Considerations for delayed-onset spinal arachnoid web after intracranial subarachnoid hemorrhage.","authors":"Georgia Wong, Gnel Pivazyan, Jeffrey M Breton, Ehsan Dowlati, Daniel R Felbaum","doi":"10.4103/bc.bc_99_23","DOIUrl":"10.4103/bc.bc_99_23","url":null,"abstract":"<p><p>Spinal arachnoid web (AW) is a rare condition causing spinal cord-related issues. Its cause is often idiopathic but can be linked to past trauma or spine surgery. We describe two cases of AWs that developed after subarachnoid hemorrhage (SAH). Case #1 is a 71-year-old male with nonaneurysmal SAH who developed myelopathy 1 year later. Magnetic resonance imaging revealed upper thoracic cord edema and an AW. Case #2 is a 57-year-old female who underwent coiling of a ruptured basilar artery aneurysm and ventriculoperitoneal shunting for hydrocephalus. Twenty months later, she developed mid-thoracic AW requiring surgical resection. Both patients showed symptom improvement postresection avoiding further reoperation. History of SAH is emerging as a risk factor for AW development, emphasizing the importance of monitoring delayed-onset myelopathy and back pain in recent SAH patients.</p>","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"10 2","pages":"89-93"},"PeriodicalIF":2.3,"publicationDate":"2024-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11259322/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141733558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of high-altitude and cold environment on brain and heart damage in rats with hemorrhagic shock.","authors":"Jun Xu, Wantong Yu, Ning Li, Sijie Li, Xiaojie Wang, Chen Gao, Feng-Yong Liu, Xunming Ji, Changhong Ren","doi":"10.4103/bc.bc_24_24","DOIUrl":"10.4103/bc.bc_24_24","url":null,"abstract":"<p><strong>Background: </strong>Hemorrhagic shock (HS) causes severe organ damage, worsened by high-altitude conditions with lower oxygen and temperatures. Existing research lacks specific insights on brain and heart damage under these conditions. This study hypothesizes that high-altitude and cold (HAC) environments exacerbate HS-induced damage in the brain and heart, aiming to improve treatment strategies.</p><p><strong>Materials and methods: </strong>Twenty-four male Sprague-Dawley (SD) rats (200-250 g of weight) were randomly assigned into sham, HS + normal, HS + HAC (4,000 m), and HS + HAC (6,000 m). The HS model was established in SD rats (35% loss of total blood volume), and histopathological injuries of the brain and heart were detected using hematoxylin and eosin staining, Sirius red staining, and immunohistochemistry. Apoptosis of the brain and heart tissues was detected by terminal transferase-mediated dUTP nick end labeling (TUNEL) immunofluorescence staining. To determine the levels of tumor necrosis factor-α (TNF-α), interferon-gamma (IFN-γ), monocyte chemoattractant protein-1 (Mcp-1), BCL2-associated X (BAX), and myeloid cell leukemia-1 (Mcl-1) protein, western blotting assay was used.</p><p><strong>Results: </strong>The HAC environment induced pathological damage to the brain and heart and aggravated the degree of cardiac fibrosis in HS rats. However, it did not cause apoptosis of the brain and heart. In addition, it upregulated TNF-α, IFN-γ, Mcp-1, and BAX protein levels, but downregulated Mcl-1 protein levels (<i>P</i> < 0.05).</p><p><strong>Conclusions: </strong>The HAC environment aggravated the degree of brain and heart damage in HS rats, which may be related to neuron nucleus pyknosis, myocardial fibrosis, and inflammatory and apoptosis activation.</p>","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"10 2","pages":"174-183"},"PeriodicalIF":2.3,"publicationDate":"2024-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11259326/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141733634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The development of the neurocritical care specialty in China based on the analysis of neurocritical care unit volume and quality.","authors":"Yingying Su, Junfang Teng, Suyue Pan, Wen Jiang, Furong Wang, Fei Tian, Jing Jing, Huijin Huang, Jie Cao, Huaiqiang Hu, Liping Liu, Wei Li, Cheng Liang, Liansheng Ma, Xuegang Meng, Linyu Tian, Changqing Wang, Lihua Wang, Yan Wang, Zhenhai Wang, Zhiqiang Wang, Zunchun Xie, Mingyao You, Jun Yuan, Chaosheng Zeng, Li Zeng, Le Zhang, Lei Zhang, Xin Zhang, Yongwei Zhang, Bin Zhao, Saijun Zhou, Zhonghe Zhou","doi":"10.4103/bc.bc_71_23","DOIUrl":"https://doi.org/10.4103/bc.bc_71_23","url":null,"abstract":"<p><strong>Purpose: </strong>Through three neurocritical care unit (NCCU) surveys in China, we tried to understand the development status of neurocritical care and clarify its future development.</p><p><strong>Methods: </strong>Using a cross-sectional survey method and self-report questionnaires, the number and quality of NCCUs were investigated through three steps: administering the questionnaire, sorting the survey data, and analyzing the survey data.</p><p><strong>Results: </strong>At the second and third surveys, the number of NCCUs (76/112/206) increased by 47% and 84%, respectively. The NCCUs were located in tertiary grade A hospitals or teaching hospitals (65/100/181) in most provinces (24/28/29). The numbers of full-time doctors (359/668/1337) and full-time nurses (904/1623/207) in the NCCUs increased, but the doctor-bed ratio and nurse-bed ratio were still insufficient (0.4:1 and 1.3:1).</p><p><strong>Conclusion: </strong>In the past 20 years, the growth rate of NCCUs in China has accelerated, while the allocation of medical staff has been insufficient. Although most NCCU hospital bed facilities and instruments and equipment tend to be adequate, there are obvious defects in some aspects of NCCUs.</p>","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"10 1","pages":"67-76"},"PeriodicalIF":1.9,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11034439/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140847805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Overt nickel and cobalt hypersensitivity after pipeline embolization device placement: A case report.","authors":"Artur Eduardo Martio, Daniel Marchi Kieling, Luciano Bambini Manzato, José Ricardo Vanzin","doi":"10.4103/bc.bc_85_23","DOIUrl":"https://doi.org/10.4103/bc.bc_85_23","url":null,"abstract":"<p><p>Nickel and cobalt are frequently found in metallic alloys used in the manufacture of aneurysm clips and endovascular prostheses, such as the pipeline embolization device (PED). Nickel hypersensitivity can affect up to 15% of the population, however, it is very rarely overt in patients who undergo endovascular stent placement. Here, we present the case of a 35-year-old woman who developed allergic symptoms after PED placement and was later confirmed to be allergic to both nickel and cobalt by patch testing. Fortunately, she responded well to pharmacologic treatment, rendering surgical intervention unnecessary. To the best of our knowledge, this is the first report of symptomatic nickel hypersensitivity, and the second report of symptomatic cobalt allergy caused by the PED. Despite its low prevalence, we believe that surgeons should actively inquire patients in the postoperative period about allergic symptoms, to facilitate early diagnosis and treatment.</p>","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"10 1","pages":"85-88"},"PeriodicalIF":1.9,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11034441/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140847940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endogenous defense mechanism-based neuroprotection in large-vessel acute ischemic stroke: A hope for future.","authors":"Deepak Goel, Sushant Shangari, Manish Mittal, Ashwani Bhat","doi":"10.4103/bc.bc_56_23","DOIUrl":"https://doi.org/10.4103/bc.bc_56_23","url":null,"abstract":"<p><strong>Background: </strong>Stroke is a leading cause of morbidity and mortality worldwide and a leading cause of disability. None of the neuroprotective agents have been approved internationally except edaravone in Japanese guidelines in acute ischemic stroke. We here discuss that there are two types of endogenous defense mechanisms (EDMs) after acute stroke for neuromodulation and neuroregeneration, and if both can be activated simultaneously, then we can have better recovery in stroke.</p><p><strong>Aims and objectives: </strong>We aimed to study the effect of combination of neuroprotection therapies acting on the two wings of EDM in acute large-vessel middle cerebral artery (LMCA) ischemic stroke.</p><p><strong>Methods: </strong>Sixty patients of LMCA stroke were enrolled and randomized within 72 h into two groups of 30 patients each. The control group received standard medical care without any neuroprotective agents while the intervention group received standard medical care combined with oral citicoline with vinpocetine for 3 months with initial 1 week intravenous and edaravone and cerebrolysin injection, started within 72 h of onset of stroke. Patients were assessed on the basis of the National Institutes of Health Stroke Scale, Fugl-Meyer Assessment Score, Glasgow Coma Scale, and Mini-Mental Status Examination at admission, discharge, and after 90 days.</p><p><strong>Results: </strong>The intervention group showed significant and early improvements in motor as well as cognitive recovery.</p><p><strong>Conclusion: </strong>Combination therapy for neuroprotection which is acting on two pathways of EDM can be useful in functional recovery after acute ischemic stroke.</p>","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"10 1","pages":"51-59"},"PeriodicalIF":1.9,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11034449/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140856022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A narrative review of intravascular catheters in therapeutic hypothermia.","authors":"Yuan Gao, Ming Li, Miaowen Jiang, Yang Zhang, Xunming Ji","doi":"10.4103/bc.bc_32_23","DOIUrl":"https://doi.org/10.4103/bc.bc_32_23","url":null,"abstract":"<p><p>Therapeutic hypothermia (TH) has been regarded as a promising neuroprotective method for acute ischemic stroke (AIS) for decades. During the development of TH, most researchers focused on improving hypothermic benefits by optimizing treatment processes and conditions. Intravenous thrombolysis and endovascular thrombectomy, for instance, have been introduced into AIS treatment. However, the lack of specialized intervention consumables, especially intervention catheter, led to inaccurate and uncontrolled hypothermic temperature, limited the efficacy of TH. In this review, intervention catheters as well as accessory equipment utilized in TH treatment has been summarized. Hopefully, this review may inspire the future development of TH specialized intervention catheter, enhance the outcome of TH, and neuroprotective efficacy in AIS.</p>","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"10 1","pages":"11-20"},"PeriodicalIF":1.9,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11034446/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140851587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors for intraprocedural hypoxemia in patients with acute cerebral ischemia treated with vascular intervention and its impact on prognosis: A retrospective cohort study.","authors":"Zhiwei Gu, Aiqin Yin, Li Lu, Yi Lu, Bei Jiang, Limin Yin","doi":"10.4103/bc.bc_50_23","DOIUrl":"https://doi.org/10.4103/bc.bc_50_23","url":null,"abstract":"<p><strong>Background: </strong>Acute cerebral infarction (ACI) is one of the most common ischemic cerebrovascular diseases in neurology, with high morbidity, mortality, and disability. Early thrombolytic treatment of ACI has significant efficacy, but intraprocedural complications of hypoxemia can significantly reduce the efficacy. This study aims to analyze the risk factors for intraprocedural hypoxemia in patients with ACI, so as to take effective measures in advance to reduce the likelihood of adverse patient outcomes.</p><p><strong>Methods: </strong>We retrospectively analyzed a total of 238 patients with ACI treated with vascular interventions from May 2017 to May 2022. To assess and collate the patients' characteristics, factors associated with the development of intraprocedural hypoxemia. The independent risk factors for the development of intraprocedural hypoxemia were analyzed by binary logistic regression.</p><p><strong>Results: </strong>A total of 238 patients were included in this study. Of these, intraprocedural hypoxemia occurred in 89 (37.4%). The results showed that old age (odds ratio [OR] = 2.666, <i>P</i> = 0.009), obesity (OR = 3.029, <i>P</i> = 0.003), smoking history (OR = 2.655, <i>P</i> = 0.010), preoperative oxygen saturation (SpO₂) (OR = 0.001, <i>P</i> = 0.042), preoperative C-reactive protein (OR = 1.216, <i>P</i> = 0.002), and time from puncture to vascular recanalization (OR = 1.135, <i>P</i> = 0.000) were independent risk factors for intraprocedural hypoxemia in patients. The prognosis of the patients was assessed according to the modified Rankin scale, and the prognosis of the nonhypoxemia group was significantly better than that of the hypoxemia group. Regression analysis showed that intraprocedural hypoxemia (OR = 0.360, <i>P</i> = 0.001), postoperative lower extremity vein thrombosis (OR = 0.187, <i>P</i> = 0.018), hydrocephalus (OR = 0.069, <i>P</i> = 0.015), intracranial hemorrhage (OR = 0.116, <i>P</i> = 0.002), and reocclusion (OR = 0.217, <i>P</i> = 0.036) were independent risk factors for poor prognosis.</p><p><strong>Conclusions: </strong>Currently, intravascular hypoxemia in patients with ACI has a serious impact on prognosis. Clinical work should attach great importance to the clinical characteristics of patients, identify relevant risk factors, and aggressively take personalized therapeutic actions to improve patients' prognosis.</p>","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"10 1","pages":"42-50"},"PeriodicalIF":1.9,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11034448/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140851725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}