Brain Circulation最新文献

{"title":"Remote cerebral vasospasm following elective clipping of middle cerebral artery bifurcation-A1 aneurysms: A correspondence and review of putative pathophysiological mechanisms.","authors":"Lykourgos Anastasopoulos, Eirini Charalampopoulou, Eleftherios Neromyliotis, Vasileios Mamalis, Eftychios Archontakis, Christos Koutsarnakis","doi":"10.4103/bc.bc_153_24","DOIUrl":"10.4103/bc.bc_153_24","url":null,"abstract":"","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"11 2","pages":"153-158"},"PeriodicalIF":2.3,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12164793/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alteplase in early recurrent ischemic stroke: A case reevaluating the 3-month exclusion criteria for thrombolysis.","authors":"Rajinder Kumar, Dinesh Verma, Jaswinder Singh","doi":"10.4103/bc.bc_170_24","DOIUrl":"10.4103/bc.bc_170_24","url":null,"abstract":"","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"11 3","pages":"243-246"},"PeriodicalIF":4.8,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12367259/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144944019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Posterior condylar canal dural arteriovenous fistulas.","authors":"Xin Su, Tongyue Li, Jiachen Wang, Yongjie Ma, Hongqi Zhang, Peng Zhang","doi":"10.4103/bc.bc_54_24","DOIUrl":"10.4103/bc.bc_54_24","url":null,"abstract":"","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"11 3","pages":"231-235"},"PeriodicalIF":4.8,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12367261/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Concurrent treatment of motor deficits, cognitive deficits, and depression using transcranial direct current stimulation in a patient with stroke: A case study.","authors":"Sujita Kumar Kar, Rahul Prajapati, Babli Kumari, Priyanshi Chaudhary, Mohita Joshi","doi":"10.4103/bc.bc_73_24","DOIUrl":"10.4103/bc.bc_73_24","url":null,"abstract":"","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"11 2","pages":"166-168"},"PeriodicalIF":2.3,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12164796/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cerebral venous thrombosis: A comprehensive narrative review.","authors":"Mosaad Omar Almegren","doi":"10.4103/bc.bc_158_24","DOIUrl":"10.4103/bc.bc_158_24","url":null,"abstract":"<p><p>Cerebral venous thrombosis (CVT) is a rare cause of cerebral infarction, accounting for <1% of stroke cases worldwide. The pathophysiology of CVT is multifactorial, encompassing the direct effects of thrombosis, interference with the blood-brain barrier and development of cerebral edema. Several genetic and acquired risk factors of CVT have been identified, more recently this includes the pro-thrombotic effects of coronavirus disease of 2019 infection. CVT can present with wide variation of clinical characteristics, with headache being the most common clinical manifestation. Diagnosis is based on radiological imaging. The mainstay of CVT management is prompt initiation of anti-coagulation. Failure to recognize insidious symptoms of CVT, will lead to a delay in diagnosis and consequently treatment which eventually lead to significant complications, including neurological disability and death. The aim of this narrative review is to consolidate the existing knowledge on CVT, a rare condition with a challenging diagnosis and treatment.</p>","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"11 3","pages":"178-186"},"PeriodicalIF":4.8,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12367267/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144944050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of antioxidant therapy in modulating neuropathic pain: A systematic review of mechanistic insights and research trends (2003-2024).","authors":"Zikai Xu, Zhen Li, Ying Dong, Yao Chen, Ming Li, Baoying Song, Yang Zhang, Miaowen Jiang, Xuxiang Zhang","doi":"10.4103/bc.bc_72_24","DOIUrl":"10.4103/bc.bc_72_24","url":null,"abstract":"<p><p>This bibliometric analysis investigates the role of antioxidant therapy in addressing neuropathic pain, emphasizing mechanistic insights and research trends from 2003 to 2024. Neuropathic pain, often unresponsive to standard treatments, is closely associated with oxidative stress as a key factor in its pathophysiology. This study utilizes the Web of Science Core Collection to analyze 699 articles related to \"antioxidants\" and \"neuropathic pain.\" CiteSpace software was employed to examine publication trends, global collaborations, co-citation networks, and research hotspots. Results indicate a consistent rise in research activity, peaking in 2022, with China, India, and Italy as leading contributors. The University of Florence and Universidade Federal de Santa Maria emerged as prominent institutions, while influential authors included Pol Olga and Trevisan Gabriela. Key studies highlighted oxidative stress and neuropathic pain mechanisms, with neuroinflammation and specific molecular pathways gaining attention as emerging research foci. The findings underscore the growing interest in antioxidant therapies as potential interventions for neuropathic pain. Despite significant advances in understanding underlying mechanisms, there is a need for further exploration of novel antioxidants and their clinical applications. Enhanced international collaboration and the use of advanced molecular techniques are essential to drive future progress in this field.</p>","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"11 2","pages":"113-126"},"PeriodicalIF":2.3,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12164787/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Flow diversion for acutely ruptured intracranial aneurysms: A single-center retrospective analysis of 30 consecutive cases.","authors":"Arevik Abramyan, Mena Samaan, Kaustav Chattopadhyay, Siddhant Kumarapuram, Srihari Sundararajan, Hai Sun, Emad Nourollah-Zadeh, Sudipta Roychowdhury, Gaurav Gupta","doi":"10.4103/bc.bc_132_24","DOIUrl":"10.4103/bc.bc_132_24","url":null,"abstract":"<p><strong>Objectives: </strong>When presented with acutely ruptured aneurysms, neurosurgeons may elect to use flow diverters (FDs). However, with the limited evidence concerning their safety and the potential thromboembolic and hemorrhagic complications, their use is extremely infrequent and often quite limited. In this study, we evaluated treatment-related complications, as well as clinical and radiological outcomes, in patients treated with FD stents for acutely ruptured intracranial aneurysms.</p><p><strong>Materials and methods: </strong>We conducted a retrospective review of patients treated with FDs within 15 days postsubarachnoid hemorrhage from 2012 to 2024. Patient demographics, aneurysm characteristics, procedural specifics, along with clinical and imaging follow-ups were assessed.</p><p><strong>Results: </strong>The study included 30 patients with a mean age of 55.6 years. Most aneurysms were located within the anterior circulation and were either small or medium-sized. Morphologically, aneurysms were saccular (43.3%), blister-like (40%), and fusiform/dissecting (16.7%). The mean time from rupture onset to treatment was 4.4 days. FD release was successfully achieved in all cases. Posttreatment rebleeding occurred in 10% of patients, ischemic complications in 6.7%, and treatment-related mortality was 6.6%, with an overall mortality of 13.3%. At discharge, 70% of patients achieved a favorable functional outcome. The mean available radiological follow-up period was 26 months, with complete aneurysm occlusion observed in 57.1% of patients at 1 month and in 100% of those available (40%) for follow-up after 1 year.</p><p><strong>Conclusions: </strong>Flow diversion for acutely ruptured aneurysms demonstrates promising outcomes, although careful patient selection and alternative treatment consideration are essential. Future prospective, multicenter studies are needed to validate preliminary findings and optimize treatment protocols for this high-risk patient population.</p>","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"11 2","pages":"135-142"},"PeriodicalIF":2.3,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12164798/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pleomorphic xanthoastrocytoma with anaplastic features.","authors":"Alejandra A Arévalo-Sáenz, Borja Ferrández-Pujante, Fernando J Rascón-Ramírez","doi":"10.4103/bc.bc_71_24","DOIUrl":"10.4103/bc.bc_71_24","url":null,"abstract":"","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"11 3","pages":"236-239"},"PeriodicalIF":4.8,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12367255/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144944080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Moyamoya disease in early infancy: Report of youngest Indian infant.","authors":"Pradeep Kumar Gunasekaran, Arushi Gahlot Saini, Vivek Gupta","doi":"10.4103/bc.bc_115_24","DOIUrl":"10.4103/bc.bc_115_24","url":null,"abstract":"","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"11 2","pages":"169-170"},"PeriodicalIF":2.3,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12164791/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protocol for a prospective 1-year follow-up investigation on normobaric hyperoxia in conjunction with endovascular treatment for acute ischemic stroke (OPENS-2L) trial.","authors":"Ming Wei, Xing Wang, Sifei Wang, Shuling Liu, Xunming Ji, Weili Li","doi":"10.4103/bc.bc_29_24","DOIUrl":"10.4103/bc.bc_29_24","url":null,"abstract":"<p><strong>Introduction: </strong>Ongoing research endeavors seek to identify neuroprotective drugs capable of mitigating brain cell necrosis and reperfusion injury by protecting the ischemic penumbra. Despite these efforts, the quest for effective neuroprotective agents remains elusive. Encouragingly, preliminary investigations, including basic experiments and single-center exploratory studies, have demonstrated the neuroprotective properties of normobaric hyperoxia (NBO). In pursuit of validating and expanding upon these findings, we have conducted a multicenter, prospective, randomized, controlled clinical trial known as OPENS-2. However, the OPENS-2 study only assessed outcomes at a 90-day endpoint, leaving uncertainties regarding the potential long-term benefits of NBO in stroke management. Thus, to address this gap in knowledge, we will initiate a long-term follow-up trial, OPENS-2L, building upon the foundation laid by the OPENS-2 study.</p><p><strong>Materials and methods: </strong>This prospective, randomized controlled clinical trial will enroll 280 patients at a 1:1 ratio. Patients will be randomly divided into the NBO combined with the endovascular treatment group, where they will receive 10 L/min of oxygen through a mask, or the control group, where they will receive 1 L/min of oxygen.</p><p><strong>Results: </strong>The primary endpoint of this study is the modified Rankin Scale (mRS) score at 1 year. Secondary endpoints include mRS 0-2, mRS 0-3, mRS 0-1 scores, Barthel index, and the EuroQol-5 Dimension score at 1 year. Safety endpoints encompass all-cause mortality at 1 year and the incidence of major vascular events.</p><p><strong>Conclusion: </strong>If this trial yields positive outcomes, it would furnish crucial evidence for guiding future neuroprotective research endeavors. Overall, the insights gained from this study hold the potential to illuminate the long-term benefits of NBO combined with endovascular treatment in improving stroke outcomes, thereby shaping the landscape of stroke management practices.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov NCT05039697.</p>","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"11 2","pages":"127-134"},"PeriodicalIF":2.3,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12164797/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}