Brain Circulation最新文献_第2页

Antiplatelet therapy after intravenous thrombolysis in acute ischemic stroke: No longer one-size-fits-all. 急性缺血性卒中静脉溶栓后抗血小板治疗：不再一刀切。

IF 5.2 4区医学

Brain Circulation Pub Date : 2026-01-27 eCollection Date: 2026-04-01 DOI: 10.4103/bc.bc_153_25

Jing Wang, Wenbo Zhao

引用次数: 0

Remote ischemic conditioning in the thrombectomy era: The first step toward clinical neuroprotection? 取栓时代的远程缺血调节：迈向临床神经保护的第一步？

IF 5.2 4区医学

Brain Circulation Pub Date : 2026-01-27 eCollection Date: 2026-01-01 DOI: 10.4103/bc.bc_178_25

Rolf Ankerlund Blauenfeldt

引用次数: 0

Remote ischemic conditioning for cerebral ischemia in patients with Takayasu arteritis (TARIC-1): Study protocol. Takayasu动脉炎患者脑缺血的远程缺血调节（TARIC-1）：研究方案。

IF 5.2 4区医学

Brain Circulation Pub Date : 2026-01-12 eCollection Date: 2026-04-01 DOI: 10.4103/bc.bc_162_24

Shuangfeng Huang, Fang Kong, Wenbo Zhao, Changhong Ren, Omar Elmadhoun, Yuchuan Ding, Xunming Ji, Yi Zhao, Sijie Li

{"title":"Remote ischemic conditioning for cerebral ischemia in patients with Takayasu arteritis (TARIC-1): Study protocol.","authors":"Shuangfeng Huang, Fang Kong, Wenbo Zhao, Changhong Ren, Omar Elmadhoun, Yuchuan Ding, Xunming Ji, Yi Zhao, Sijie Li","doi":"10.4103/bc.bc_162_24","DOIUrl":"10.4103/bc.bc_162_24","url":null,"abstract":"Aim: The purpose of this study is to investigate the safety and effectiveness of remote ischemic conditioning (RIC) as a therapeutic intervention for cerebral ischemia in patients with Takayasu arteritis (TA).Methods: TARIC-1 is a randomized, double-blind, parallel-group pilot trial conducted at Xuanwu Hospital, Capital Medical University. Participants with TA and reduced cerebral blood perfusion are randomly allocated to either the RIC or sham-RIC groups. Both the groups receive conventional medical care, with the RIC group receiving twice-daily sessions of 200 mmHg inflation pressure and the sham-RIC group receiving 60 mmHg inflation pressure, for 24 consecutive weeks.Outcomes: The primary outcome is the change in mean cerebral blood flow across the entire brain and regions of interest following the 24-week RIC treatment. Secondary outcomes include clinical assessments using the Indian Takayasu Clinical Activity Score 2010, Vasculitis Damage Index, and Birmingham Vasculitis Activity Score at 24 weeks postintervention. Changes in arterial transit time and the incidence of major adverse cerebrovascular events are additional secondary outcomes. Safety outcomes include mortality and any adverse events, including skin changes and pain ratings, within the 24-week period.Sample size estimates: This pilot study plans to enroll 22 patients per group, totaling 44 participants.Conclusions: In individuals with TA, RIC may be a well-tolerated treatment that enhances cerebral perfusion and lowers the risk of ischemic cerebrovascular episodes.TRIAL REGISTRATION: http://www.clinicaltrials.gov (identifier: NCT06178419).","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"12 2","pages":"118-123"},"PeriodicalIF":5.2,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13152235/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147866947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Forward thinking in reperfusion therapy for acute ischemic stroke. 急性缺血性脑卒中再灌注治疗的前瞻性思考。

IF 5.2 4区医学

Brain Circulation Pub Date : 2025-12-26 eCollection Date: 2025-10-01 DOI: 10.4103/bc.bc_161_25

Wenbo Zhao, Marc Fisher, Xunming Ji

引用次数: 0

Neurosurgical management of intracerebral hemorrhage in anticoagulated patients: Outcomes and reversal strategies. 抗凝患者脑出血的神经外科治疗：结果和逆转策略。

IF 4.8 4区医学

Brain Circulation Pub Date : 2025-12-26 eCollection Date: 2025-10-01 DOI: 10.4103/bc.bc_175_25

Vyom Grover, Yuchuan Ding

引用次数: 0

Erratum: Enhanced oxidative stress response and neuroprotection of combined limb remote ischemic conditioning and atorvastatin after transient ischemic stroke in rats. 误：短暂性脑卒中后肢体远端缺血调节联合阿托伐他汀增强氧化应激反应和神经保护作用。

IF 4.8 4区医学

Brain Circulation Pub Date : 2025-12-26 eCollection Date: 2025-10-01 DOI: 10.4103/bc.bc_202_25

引用次数: 0

Pituitary apoplexy in the setting of adrenocorticotropic hormone-secreting adenoma: A systematic review and illustrative case. 垂体卒中并发促肾上腺皮质激素分泌腺瘤：一个系统回顾和说明性病例。

IF 4.8 4区医学

Brain Circulation Pub Date : 2025-12-26 eCollection Date: 2025-10-01 DOI: 10.4103/bc.bc_43_25

Kara A Parikh, Jordan T Roach, Ho Jun Yun, Yuchuan Ding, Andrew B Boucher

{"title":"Pituitary apoplexy in the setting of adrenocorticotropic hormone-secreting adenoma: A systematic review and illustrative case.","authors":"Kara A Parikh, Jordan T Roach, Ho Jun Yun, Yuchuan Ding, Andrew B Boucher","doi":"10.4103/bc.bc_43_25","DOIUrl":"10.4103/bc.bc_43_25","url":null,"abstract":"Background: Cushing's disease is a commonly described pathology in which an excess of adrenocorticotropic hormone (ACTH) is produced by a functional pituitary adenoma. Pituitary apoplexy is an even less common pathology that occurs due to acute hemorrhage or infarct of pituitary adenomas, more commonly in nonfunctional adenomas. Very rarely do these uncommon pathologies occur simultaneously in the same patient. We present an updated systematic review on presentation and management of apoplexy in the setting of ACTH-secreting adenoma, with an unusual case illustrating presentation and management of these complex concomitant pathologies.Methods: A systematic review was conducted in accordance with PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, looking at literature discussing concomitant ACTH-producing adenoma and apoplexy.Results: Fifteen articles were included after reviewing 355 articles published from 1968-2024. Median age was 35 years. Majority of the patients (63.2%) were female. Visual acuity or visual field loss on presentation occurred in 12 (63.2%) and 7 (36.8%) patients. While 16 patients (84.2%) were treated with surgical intervention. The average follow up time was 16.7 months.Conclusion: Pituitary apoplexy in the setting of an ACTH-secreting adenoma is an infrequently encountered scenario that can present with a confounding clinical picture. Proper recognition and diagnosis are important as the proper preoperative clinical suspicion and diagnosis alters primary goals of surgical intervention.","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"11 4","pages":"333-338"},"PeriodicalIF":4.8,"publicationDate":"2025-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12795493/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145965162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

China Stroke Prevention and Control Report 2024: An executive summary. 中国脑卒中防治报告2024：执行摘要。

IF 4.8 4区医学

Brain Circulation Pub Date : 2025-12-15 eCollection Date: 2025-10-01 DOI: 10.4103/bc.bc_198_25

{"title":"China Stroke Prevention and Control Report 2024: An executive summary.","authors":"","doi":"10.4103/bc.bc_198_25","DOIUrl":"10.4103/bc.bc_198_25","url":null,"abstract":"Stroke remains a leading cause of death and disability in China, imposing a substantial burden on public health and the economy. This China Stroke Prevention and Control Report 2024 summary report synthesizes the latest epidemiological data, risk factor management, stroke care systems, quality metrics, and screening interventions based on national surveys, the Global Burden of Disease 2021 study, and the China Stroke High-Risk Population Screening and Intervention Program (CSHR Program). In 2021, China reported 4.09 million new stroke cases, 26.34 million prevalent cases, and 2.59 million deaths, with ischemic stroke comprising the majority. Despite modest declines in age-standardized incidence (3%) and mortality (26%) from 2010 to 2021, absolute numbers continue to rise due to population aging. Key risk factors include hypertension (prevalence 25.5%, control 14.1%), diabetes (11.7%), dyslipidemia (42.1%), and lifestyle factors like smoking and physical inactivity. China's stroke care infrastructure has expanded to 1,962 centers by 2023, with improvements in prehospital response (median call-to-arrival: 39 min) and acute treatments: intravenous thrombolysis rate 9.39%, mechanical thrombectomy rate 2.56%. The CSHR Program screened over 13 million high-risk individuals, revealing gains in awareness but persistent gaps in risk factor control. Analysis of 433,284 hospitalized stroke patients showed median ages of 68, 62, and 61 years for ischemic, intracerebral hemorrhagic, and subarachnoid hemorrhagic strokes, respectively, with in-hospital mortality of 1.20% and three-month disability of 18.13%. Despite progress, challenges remain, including rural-urban disparities, increasing incidence among younger adults, and higher burden in northern regions. Future efforts should focus on primary prevention, equitable access, and integrated care to reduce the national and global stroke burden.","PeriodicalId":9288,"journal":{"name":"Brain Circulation","volume":"11 4","pages":"251-260"},"PeriodicalIF":4.8,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12795483/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145964993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Outcomes of early targeted embolization for ruptured arteriovenous malformation-associated aneurysms: A single-center study. 早期靶向栓塞治疗破裂动静脉畸形相关动脉瘤的结果：一项单中心研究

IF 4.8 4区医学

Brain Circulation Pub Date : 2025-12-03 eCollection Date: 2025-10-01 DOI: 10.4103/bc.bc_89_25

Koki Onodera, Kuya Azekami, Masataka Yoshimura, Hiroki Kurita, Shinya Kohyama

引用次数: 0

There is currently no evidence that long-COVID-19 leads to neurodegenerative diseases such as SDAT, amyotrophic lateral sclerosis, or Parkinson's disease. 目前没有证据表明长期感染covid -19会导致SDAT、肌萎缩性侧索硬化症或帕金森病等神经退行性疾病。

IF 4.8 4区医学

Brain Circulation Pub Date : 2025-12-03 eCollection Date: 2025-10-01 DOI: 10.4103/bc.bc_81_25

Josef Finsterer

引用次数: 0