BMC Research Notes最新文献_第5页

Seedling growth rate and root traits in the maize Nested Association Mapping (NAM) panel. 玉米巢式关联图谱（NAM）面板的幼苗生长速率和根系性状。

IF 1.6

BMC Research Notes Pub Date : 2025-05-08 DOI: 10.1186/s13104-025-07279-z

Maya Montoya-Pimolwatana, Tai McClellan Maaz, Michael Kantar, Michael Muszynski, Yuriy Mileyko, Rishi Prasadh, Ishwora Dhungana, Kenneth Kiehl, Abigail H Ana, Alanna Nguyen, Alycia Tausaga, Amanda Godfrey, Amanda K Nitta, Bryceson Tugade, D JadenYamagata-Santos, Elizabeth Swantek, Ethan S Morrell, G'Voni Kalaiwaa, Germaine Lindsay Juan, Gunnar Larsen, India Kawelolani Ching, Jesse Mikasobe-Kealiinohomoku, Jessica Araszewski, Joseph Carmelo M Averion, Katie Strachan, Kayla-Marie A Torres, Keara Botanes, Keilah C Wilkes, Lydia Rigge, Malisa Lo, Nicholas Carr, Noa Brenner, Olivia Johnson, Roma Amor B Malasarte, Ruby Noland, Stefano Naldini, Stephenie Andriana Santos, Tomas Pierce, Urban Halpern, Zeus Gean Paul Miguel, Zhuocheng Gan, Nhu H Nguyen

{"title":"Seedling growth rate and root traits in the maize Nested Association Mapping (NAM) panel.","authors":"Maya Montoya-Pimolwatana, Tai McClellan Maaz, Michael Kantar, Michael Muszynski, Yuriy Mileyko, Rishi Prasadh, Ishwora Dhungana, Kenneth Kiehl, Abigail H Ana, Alanna Nguyen, Alycia Tausaga, Amanda Godfrey, Amanda K Nitta, Bryceson Tugade, D JadenYamagata-Santos, Elizabeth Swantek, Ethan S Morrell, G'Voni Kalaiwaa, Germaine Lindsay Juan, Gunnar Larsen, India Kawelolani Ching, Jesse Mikasobe-Kealiinohomoku, Jessica Araszewski, Joseph Carmelo M Averion, Katie Strachan, Kayla-Marie A Torres, Keara Botanes, Keilah C Wilkes, Lydia Rigge, Malisa Lo, Nicholas Carr, Noa Brenner, Olivia Johnson, Roma Amor B Malasarte, Ruby Noland, Stefano Naldini, Stephenie Andriana Santos, Tomas Pierce, Urban Halpern, Zeus Gean Paul Miguel, Zhuocheng Gan, Nhu H Nguyen","doi":"10.1186/s13104-025-07279-z","DOIUrl":"https://doi.org/10.1186/s13104-025-07279-z","url":null,"abstract":"This paper characterizes variation in shoot and root traits collected from the founders of the Maize Nested Association Mapping panel, which was designed to maximize genetic diversity while ensuring appropriate flowering in eastern North America. Here, we present a detailed account of greenhouse experiments conducted by four cohorts of undergraduate research interns at the University of Hawai'i at Mānoa. We summarize data collection, data cleaning procedures, and present data for 38 phenotypic variables for 24 genotypes with the number of plant replicates ranging from 3 to 20. The genotype B73 served as our experimental control to enable comparison over the four years. We also grew a subset of genotypes under different abiotic stress treatments to assess the phenotypic plasticity. These data can be used to predict the potential for different lines to function and capacity to adapt to different environments. Data are published on GitHub repositories, and have large reuse potential by the scientific community, as well as educators of undergraduate and graduate instruction.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"206"},"PeriodicalIF":1.6,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12063293/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Ficolin-3 deficiency as a risk factor in the development of rheumatic heart disease. 评价Ficolin-3缺乏是风湿性心脏病发展的一个危险因素。

IF 1.6

BMC Research Notes Pub Date : 2025-05-08 DOI: 10.1186/s13104-025-07251-x

Zahra Parker, M Taariq Salie, Kélin Engel, Liesl J Zühlke, Mark E Engel, Timothy F Spracklen

{"title":"Evaluation of Ficolin-3 deficiency as a risk factor in the development of rheumatic heart disease.","authors":"Zahra Parker, M Taariq Salie, Kélin Engel, Liesl J Zühlke, Mark E Engel, Timothy F Spracklen","doi":"10.1186/s13104-025-07251-x","DOIUrl":"https://doi.org/10.1186/s13104-025-07251-x","url":null,"abstract":"Objective: Ficolin-3 is a crucial protein for the activation of the complement system. Previous work has indicated this protein may play a role in the pathogenesis of rheumatic heart disease (RHD), and it has been hypothesised that ficolin-3 has potential as a biomarker for early identification of patients with suspected RHD. This study investigated FCN3 gene polymorphisms rs532781899 (c.349del) and rs4494157 (c.658 + 250 C > A) and ficolin-3 serum concentrations in an ethnically diverse cohort of 53 RHD cases and 45 healthy controls from across Africa.Results: Ficolin-3 was found to be increased by 16% in RHD patients (p = 0.03) compared to controls, but polymorphisms did not associate with the risk of developing RHD nor with ficolin-3 concentrations. Carriers of the c.349del haploinsufficiency locus had normal levels of ficolin-3, while the previously described c.658 + 250 C > A RHD susceptibility locus was found equally in cases and controls. The higher serum ficolin-3 in RHD supports the potential role of this protein in RHD pathogenesis. However, these results suggest that rs532781899 and rs4494157 are not risk factors for the development of RHD in patients from sub-Saharan Africa and would not be reliable as early-stage markers of RHD susceptibility.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"205"},"PeriodicalIF":1.6,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12060289/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143953747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intronomics-MIP: a snakemake pipeline for analyzing multilocus intron polymorphisms in species identification and population genomics. Intronomics-MIP：一种在物种鉴定和种群基因组学中分析多位点内含子多态性的蛇形管道。

IF 1.6

BMC Research Notes Pub Date : 2025-05-06 DOI: 10.1186/s13104-025-07264-6

A Scapolatiello, E Boscari, L Schiavon, N Vitulo, L Congiu

引用次数: 0

Impact of malnutrition and associated factors on rifampicin/multi-drug-resistant tuberculosis treatment outcomes among patients treated in alert and St. Peter's Specialized Hospitals, Addis Ababa, Ethiopia: a retrospective follow-up study. 营养不良及相关因素对埃塞俄比亚亚的斯亚贝巴alert和圣彼得专科医院治疗的患者利福平/耐多药结核病治疗结果的影响：一项回顾性随访研究。

IF 1.6

BMC Research Notes Pub Date : 2025-05-06 DOI: 10.1186/s13104-025-07268-2

Ekram Mohammed Siraj, Tilahun Bizuayehu Demass, Ayenew Molla Lakew, Lake Yazachew Amogne, Mulat Addis Beshaw

{"title":"Impact of malnutrition and associated factors on rifampicin/multi-drug-resistant tuberculosis treatment outcomes among patients treated in alert and St. Peter's Specialized Hospitals, Addis Ababa, Ethiopia: a retrospective follow-up study.","authors":"Ekram Mohammed Siraj, Tilahun Bizuayehu Demass, Ayenew Molla Lakew, Lake Yazachew Amogne, Mulat Addis Beshaw","doi":"10.1186/s13104-025-07268-2","DOIUrl":"https://doi.org/10.1186/s13104-025-07268-2","url":null,"abstract":"Objective: This study was aimed to assess the impact of malnutrition and associated factors on rifampicin/multi-drug-resistant tuberculosis treatment outcomes among patients treated in Alert and St. Peter's Specialized Hospitals, Addis Ababa, Ethiopia.Results: Our study included 344 RR/MDR-TB patients, of which 43.3% were undernourished. The overall unsuccessful treatment outcome was 22.1% (95% CI 0.18, 0.27). Patients with undernutrition were over eight times more likely to develop unsuccessful treatment outcomes [AOR = 8.32 (95% CI 4.48, 15.46)] compared to normal/ overweight individuals. After we computed the binary logistic regression analysis separately for patients with undernutrition and normal/ overweight nutritional status, age, residence, occupation, chest x-ray, anemia, co-morbidities, cigarette smoking, and alcohol drinking were significantly associated with unsuccessful treatment outcomes among undernourished patients, while age, HIV, and smoking were significantly associated with unsuccessful treatment outcomes among patients with normal/overweight individuals.Conclusions: In this study, undernutrition had a remarkable impact on unsuccessful treatment outcomes. Therefore, further researches need to be conducted to integrate the management of undernutrition with the DR-TB treatment program.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"204"},"PeriodicalIF":1.6,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12057184/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143973305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

CIRBP mRNA level in breast cancer is associated with HIF1α gene expression and microvascular density. 乳腺癌组织中CIRBP mRNA水平与HIF1α基因表达和微血管密度相关。

IF 1.6

BMC Research Notes Pub Date : 2025-05-04 DOI: 10.1186/s13104-025-07265-5

Sajad Monjezi, Vahid Soleimani, Maryam Cheraghzadeh, Saeed Ghanbari, Maryam Adelipour

引用次数: 0

Epidemiological analysis of Lassa fever control using novel mathematical modeling and a dual-dosage vaccination approach. 基于新型数学模型和双剂量疫苗接种方法的拉沙热控制流行病学分析。

IF 1.6

BMC Research Notes Pub Date : 2025-04-30 DOI: 10.1186/s13104-025-07218-y

Akeem Olarewaju Yunus, Morufu Oyedunsi Olayiwola

{"title":"Epidemiological analysis of Lassa fever control using novel mathematical modeling and a dual-dosage vaccination approach.","authors":"Akeem Olarewaju Yunus, Morufu Oyedunsi Olayiwola","doi":"10.1186/s13104-025-07218-y","DOIUrl":"https://doi.org/10.1186/s13104-025-07218-y","url":null,"abstract":"Lassa fever is a serious health issue in West Africa that requires deeper understanding in order to be effectively controlled. Compared to conventional integer-order methods, this study presents an improved analysis of disease dynamics, including vaccine efficacy, by utilizing fractional-order models and the Laplace Adomian Decomposition methods. This research highlights the critical role of fractional-order dynamics and vaccination impact in understanding Lassa fever transmission and evaluating control strategies. It employs stability and sensitivity analyses, as well as the next-generation matrix method, to assess the basic reproduction number. The study offers novel insights into the importance of expanded vaccination coverage, setting it apart from previous works. The study demonstrated that preventive strategies, particularly double-dose vaccinations, are extremely efficient in controlling Lassa fever and lowering infection rates. It emphasizes the significance of increasing vaccination efforts to safeguard groups that are susceptible. The findings offer important epidemiological insights, boosting efforts to eradicate the disease and improve public health in West Africa and beyond.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"199"},"PeriodicalIF":1.6,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12044729/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143970879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

MSRP-TODNet: a multi-scale reinforced region wise analyser for tiny object detection. 用于微小目标检测的多尺度增强区域明智分析仪。

IF 1.6

BMC Research Notes Pub Date : 2025-04-30 DOI: 10.1186/s13104-025-07263-7

Thulasi Bikku, K P N V Satya Sree, Srinivasarao Thota, Malligunta Kiran Kumar, P Shanmugasundaram

{"title":"MSRP-TODNet: a multi-scale reinforced region wise analyser for tiny object detection.","authors":"Thulasi Bikku, K P N V Satya Sree, Srinivasarao Thota, Malligunta Kiran Kumar, P Shanmugasundaram","doi":"10.1186/s13104-025-07263-7","DOIUrl":"https://doi.org/10.1186/s13104-025-07263-7","url":null,"abstract":"Objective: Detecting small, faraway objects in real-time surveillance is challenging due to limited pixel representation, affecting classifier performance. Deep Learning (DL) techniques generate feature maps to enhance detection, but conventional methods suffer from high computational costs. To address this, we propose Multi-Scale Region-wise Pixel Analysis with GAN for Tiny Object Detection (MSRP-TODNet). The model is trained and tested on VisDrone VID 2019 and MS-COCO datasets. First, images undergo two-fold pre-processing using Improved Wiener Filter (IWF) for artifact removal and Adjusted Contrast Enhancement Method (ACEM) for blurring correction. The Multi-Agent Reinforcement Learning (MARL) algorithm splits the pre-processed image into four regions, analyzing each pixel to generate feature maps. These are processed by the Enhanced Feature Pyramid Network (EFPN), which merges them into a single feature map. Finally, a Generative Adversarial Network (GAN) detects objects with bounding boxes.Results: Experimental results on the DOTA dataset demonstrate that MSRP-TODNet outperforms existing state-of-the-art methods. Specifically, it achieves an mAP @0.5 of 84.2%, mAP @0.5:0.95 of 54.1%, and an F1-Score of 84.0%, surpassing improved TPH-YOLOv5, YOLOv7-Tiny, and DRDet by margins of 1.7%-6.1% in detection performance. These results demonstrate the framework's effectiveness for accurate, real-time small object detection in UAV surveillance and aerial imagery.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"200"},"PeriodicalIF":1.6,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12044837/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143964918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Modeling within-host Chikungunya virus dynamics with the immune system using semi-analytical approaches. 利用半分析方法模拟宿主内基孔肯雅病毒与免疫系统的动力学。

IF 1.6

BMC Research Notes Pub Date : 2025-04-30 DOI: 10.1186/s13104-025-07252-w

Morufu Oyedunsi Olayiwola, Akeem Olarewaju Yunus, Adedapo Ismaila, Alaje, Joseph Adeleke Adedeji

{"title":"Modeling within-host Chikungunya virus dynamics with the immune system using semi-analytical approaches.","authors":"Morufu Oyedunsi Olayiwola, Akeem Olarewaju Yunus, Adedapo Ismaila, Alaje, Joseph Adeleke Adedeji","doi":"10.1186/s13104-025-07252-w","DOIUrl":"https://doi.org/10.1186/s13104-025-07252-w","url":null,"abstract":"Objective: Chikungunya fever continues to spread worldwide due to its asymptomatic nature and lack of a specific treatment. A mathematical model using the Caputo fractional order derivative is developed to study the interactions between host defense cells and Chikungunya viral particles in this research. The model's solution existence, uniqueness, and positivity are analyzed. The disease-free state threshold and Hyers-Ulam stability are established.Results: The basic reproductive number <math> <mrow><msub><mi>R</mi> <mn>0</mn></msub> <mo>≈</mo> <mn>7</mn></mrow> </math> , depict a high replication rate of the virus, indicating an increased infectiousness of uninfected cells. Sensitivity analysis shows that the invasion rate of susceptible monocytes increases spread, while antigenic immune response keeps <math><msub><mi>R</mi> <mn>0</mn></msub> </math> below 1. The Laplace Adomian Decomposition Method (LADM) is used to solve the model. Experimental outcomes suggest that the enhanced adaptive immune response, potentially influenced by nutritional support or medication, exhibits a more pronounced hysteresis effect. We observed that viral particles are cleared approximately three (3) days earlier before cell infection, potentially clearing the virus within a week. This insight could accelerate elimination of viral particles and expedite virus clearance.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"201"},"PeriodicalIF":1.6,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12044791/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of confidence/trust in the emergency department. 信心/信任在急诊科的作用。

IF 1.6

BMC Research Notes Pub Date : 2025-04-29 DOI: 10.1186/s13104-025-07266-4

Alina Abidova, Pedro Alcântara da Silva, Sérgio Moreira

引用次数: 0

Correction: Simultaneous assessment of mitochondrial DNA copy number and nuclear epigenetic age towards predictive models of development and aging. 更正：同时评估线粒体DNA拷贝数和核表观遗传年龄对发育和衰老的预测模型。

IF 1.6

BMC Research Notes Pub Date : 2025-04-27 DOI: 10.1186/s13104-025-07260-w

Phyo W Win, Julia Nguyen, Amanda L Morin, Charles E Newcomb, Shiva M Singh, Noha Gomaa, Christina A Castellani

引用次数: 0