BMC Research Notes最新文献

{"title":"Using ATP measurements to rapidly evaluate the cleanliness of spectacle surfaces.","authors":"Nazma Sultana Lupin, Birgit Fritz, Siegfried Wahl, Markus Egert","doi":"10.1186/s13104-025-07282-4","DOIUrl":"https://doi.org/10.1186/s13104-025-07282-4","url":null,"abstract":"<p><strong>Objective: </strong>Microbial contamination on used spectacles poses a potential health risk to spectacle wearers and people regularly working with worn spectacles, such as opticians. ATP measurement is widely used to evaluate the cleanliness of surfaces based on the detection of adenosine triphosphate, a molecule found in and around living cells. In this study, we investigated the suitability of this method to rapidly and easily evaluate the efficacy of different cleaning methods for spectacles. Additionally, we examined the correlation between ATP content on spectacle surfaces with aerobic and anaerobic bacterial colony counts. We swab-sampled worn spectacles and used an ATP bioluminescence assay to assess the level of cellular contamination.</p><p><strong>Results: </strong>Six cleaning methods were tested on ten worn spectacles each, and ATP levels were correlated with both aerobic and anaerobic bacterial counts. All investigated cleaning methods showed a significant median reduction of the ATP content on spectacle surfaces, between 75 and 93%. Germ counts and ATP levels showed no significant correlation for aerobic but for anaerobic cultivation. Higher anaerobic germ counts correlated positively with higher ATP levels. ATP measurement is a suitable method to rapidly and easily demonstrate the efficacy of cleaning measures for spectacle surfaces also under non laboratory conditions.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"216"},"PeriodicalIF":1.6,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12080132/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A qualitative study on preparedness requirements for responding to chemical, biological, radiological, and nuclear incidents in Iran.","authors":"Hamid Karimi Kivi, Vahid Hadi, Saeed Nazari, Peyman Namdar, Mahboobeh Afzali","doi":"10.1186/s13104-025-07272-6","DOIUrl":"10.1186/s13104-025-07272-6","url":null,"abstract":"<p><strong>Background and purpose: </strong>The sudden increase in the number of exposed individuals, diverse injuries, damage to health equipment, and disruptions in health services highlight the need for a structured response to radiological and nuclear incidents. This study aims to identify the requirements for responding to CBRN incidents in Iran. This research contributes to a deeper understanding of the complexities involved in CBRN preparedness and response in Iran, highlighting areas for potential improvement and policy development.</p><p><strong>Methodology: </strong>This qualitative research conducted in 2023 involved semi-structured interviews with 32 specialists selected through purposive sampling until data saturation was reached. Thematic analysis was employed to analyze the data.</p><p><strong>Findings: </strong>The requirements for responding to CBRN incidents were categorized into three main classes with nine subcategories: TRAINING: Effective training content, establishment of specialized training centers, identification of target audiences, educational needs assessment, and continuous education.</p><p><strong>Drills: </strong>Implementation of various operational drills and their content.</p><p><strong>Emergency response planning: </strong>Elements of response plans and evaluation of these plans.</p><p><strong>Conclusion: </strong>Timely and appropriate responses from the health system during critical phases after such incidents are crucial for mitigating adverse health effects. This study provides insights into the necessary requirements for enhancing readiness in the health sector as Iran progresses towards adopting modern technologies.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"214"},"PeriodicalIF":1.6,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12070526/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143976223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distribution of polycystic ovary syndrome (PCOS) phenotypes in Iranian women: a cross-sectional study.","authors":"Asma Kheirollahi, Hediyeh Hamidi, Akram Vatannejad","doi":"10.1186/s13104-025-07202-6","DOIUrl":"10.1186/s13104-025-07202-6","url":null,"abstract":"<p><strong>Objective: </strong>Polycystic ovary syndrome (PCOS) is a heterogeneous disorder characterized by diverse clinical and metabolic manifestations. This study aimed to investigate the prevalence of PCOS phenotypes and their association with hematological, biochemical, and hormonal parameters in PCOS, with a particular focus on infertile women and those with recurrent pregnancy loss (RPL).</p><p><strong>Results: </strong>Phenotype A was the most prevalent phenotype overall and within both infertile and RPL subgroups. However, no significant differences in hematological, biochemical, or hormonal parameters were observed among the PCOS phenotypes, except for lower RBC and hematocrit levels in phenotype F. PCOS women with RPL demonstrate significantly lower levels of RBC, hemoglobin, and hematocrit in phenotype F.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"215"},"PeriodicalIF":1.6,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12076859/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143988733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Consumers' recommendations for improving access to healthcare services to adolescents with disabilities in Ghana.","authors":"Ebenezer Mensah Gyimah, Ebenezer Dassah, Maxwell Peprah Opoku, Wisdom Kwadwo Mprah, William Nketsia, Afua Ntoaduro, Philip Atta Mensah, Cecilia Opoku, Clement Osei Tutu, Issaka Zakia, Richard Adade, Paul Okyere","doi":"10.1186/s13104-025-07267-3","DOIUrl":"10.1186/s13104-025-07267-3","url":null,"abstract":"<p><strong>Introduction: </strong>In Ghana, Adolescents with mobility and visual impairments and their families, encounter healthcare disparities, including socio-economic, physical, structural and attitudinal challenges, compared to the general population. Nonetheless, there is limited motivation to understand how to improve healthcare access for these marginalized consumers (i.e., adolescents with disabilities and their families). Consequently, the study explored marginalized consumers' recommendations for improving access to healthcare services, described in Ghana's Act 715. Informed by the qualitative descriptive design, forty-five (45) participants were purposively recruited and interviewed, adopting a semi-structured interview guide. Data gathered were subjected to content analysis and interpreted via lenses of the theory of dimensions of healthcare access.</p><p><strong>Results: </strong>The study's findings were layered within areas of improving policy-practice interphase. Consumers called on policy makers to restructure the NHIS to cover indirect costs of accessing healthcare services for adolescents with disabilities. In respect of improving practice, it was also suggested that training and education on disability phenomenon must be extended to all cadres of healthcare workers including administrative staff, who provided services to this marginalized social unit. Participants further recommended enhancing the availability of healthcare workers and services as well as ensuring respect and protection of human rights within healthcare facilities.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"213"},"PeriodicalIF":1.6,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12070534/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143976030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The investigation of apoptosis-related genes in periodontitis.","authors":"Arezou Sayad, Fatemeh Hashemian, Leila Gholami, Masoud Jamali, Elham Badrlou, Saba Sadeghpour, Naghme Nazer, Sheyda Khalilian, Soudeh Ghafouri-Fard","doi":"10.1186/s13104-025-07274-4","DOIUrl":"10.1186/s13104-025-07274-4","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims at determination of the roles of five apoptosis-related genes, namely CASP2, CASP8, BCL2, HULC and PVT1 in the pathoetiology of periodontitis via measurement of their expressions in both peripheral blood and tissues of affected persons.</p><p><strong>Results: </strong>CASP2 was over-expressed in gingiva of patients compared with healthy subjects (RME = 24.56, P < 0.001), and in both affected females and males (RME = 30.53, P = 0.03 and RME = 20.59, P = 0.01, respectively). BCL2 was higher in affected tissues compared with controls (RME = 32.28, P < 0.001) and in affected tissues of males versus controls (RME = 69.03, P < 0.001). Finally, HULC had lower level in the blood of patients (RME = 0.21, P = 0.01) and in the blood of female patients compared with normal females (RME = 0.15, P = 0.01). Other comparisons yielded no significant results. BCL2 and CASP2 had the highest diagnostic values for separation of diseased gingival tissues from normal ones. HULC has the best values in the distinction of blood samples of affected persons from control persons. Combination of transcript levels of CASP2, CASP8, BCL2, HULC and PVT1 changed AUC to 0.84 and 0.72 in tissues and blood samples, respectively. To conclude, these genes might be regarded as putative contributors in the pathophysiology of periodontitis.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"211"},"PeriodicalIF":1.6,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12070626/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143954553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minority adolescents' HIV PrEP awareness and preferences in Alabama.","authors":"Henna Budhwani, Ibrahim Yigit, Hoa L Nguyen, Josh Bruce, C Lily Bond, Andrea Johnson","doi":"10.1186/s13104-025-07273-5","DOIUrl":"10.1186/s13104-025-07273-5","url":null,"abstract":"<p><strong>Objective: </strong>In the southern United States, adolescents are at elevated risk for HIV acquisition. In Alabama, school-based sexual health and HIV prevention education is strictly regulated and does not address the unique needs of sexual and gender minority (SGM) teenagers. To inform public health efforts, we assessed SGM adolescents' HIV prevention pre-exposure prophylaxis (PrEP) awareness and modality preferences by gender, race, and ethnicity.</p><p><strong>Results: </strong>Survey data were collected in 2023-2024 from SGM adolescents aged 14-17 years, lived in Alabama, with male sex assigned at birth (N = 206). Recruitment occurred online and in-person at a charter school. Data were analyzed using chi-squares and analysis of variance, controlling for age. Over half of respondents were sexually active, but only 26% had ever been tested for HIV. Half knew about PrEP. Of those with PrEP awareness, 41.9% were aware of daily pills; 32.3% of long-acting injectable PrEP. Pill-based PrEP was highly endorsed. Trans- and gender-non-conforming adolescents reported a greater preference for on-demand pill-based PrEP compared to men who have sex with men (p =.01). Non-Hispanics had a greater preference for a 6-month long-acting injectable option compared to Hispanic adolescents (p =.04). Findings suggest the need for HIV prevention interventions tailored to southern contexts and adolescent knowledge.</p><p><strong>Trial registration: </strong>Not Applicable.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"210"},"PeriodicalIF":1.6,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12067670/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143954816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Designing and implementing a self-learning game with a problem-solving approach to improve students' personal health and healthy nutrition behavior.","authors":"Hossein Ajam Noroozi, Nader Sharifi, Hamid Joveini, Mohammad Hassan Rakhshani, Mansoureh Alipour Anbrani","doi":"10.1186/s13104-025-07244-w","DOIUrl":"10.1186/s13104-025-07244-w","url":null,"abstract":"<p><strong>Objective: </strong>This research is a quasi-experimental study conducted on male students from six elementary schools ranging from third to sixth grade in three regions of Shahrood city from March 2023 to February 2024. This study aimed to designing, implementing and evaluating a health-oriented self-learning game with a problem-solving approach in order to improve behavior in the field of personal health and healthy nutrition in elementary school students.</p><p><strong>Results: </strong>There was a significant difference between the knowledge (p = 0.01), attitude (p > 0.001) and behavior (p = 0.01) in the control and intervention groups, after the intervention, while there was no significant difference between the two groups in these variables before the intervention. The utilization of health-oriented self-learning games proved to be effective in enhancing the knowledge, attitude, and behavior of elementary school students regarding personal health and healthy nutrition.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"212"},"PeriodicalIF":1.6,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12070729/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143965851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ethical sensitivity questionnaire for nursing students: psychometric properties of the Persian version.","authors":"Amir Jalali, Azam Sharifi, Behrouz Soltany, Amirhossein Naghibzadeh, Jalal Karimi, Hooman Ghasemi, Parnia Kalhory, Khalil Moradi","doi":"10.1186/s13104-025-07276-2","DOIUrl":"https://doi.org/10.1186/s13104-025-07276-2","url":null,"abstract":"<p><strong>Objective: </strong>Nursing students' ethical sensitivity is crucial for providing high-quality patient care. Assessing this sensitivity using standardized tools is essential for both students and professional nurses. This study aimed to determine the properties of cultural adaptation and the psychometric evaluation of the Ethical Sensitivity Questionnaire for Nursing Students (ESQ-NS).</p><p><strong>Results: </strong>This methodological study, conducted between April and November 2023, involved 480 nursing students who were selected through convenience sampling. The ESQ-NS was translated into Persian following the method described by Wild et al. (2005). The data were analyzed using SPSS (version 27) and LISREL (version 8.8) software. The EFA and CFA validated a three-factor, 13-item structure for the assessment tool. The Pearson correlation coefficient demonstrated a positive and significant correlation between the items and their respective subscales of the overall scale. The reliability of the Persian version of the ESQ-NS was confirmed with a Cronbach's alpha of 0.781, a MacDonald's Omega coefficient of 0.78, and an Intraclass Correlation Coefficient (ICC) of 0.78 (CI: 0.743- 0.816). The Persian version of the ESQ-NS demonstrates acceptable reliability and validity, making it a suitable tool for evaluating the ethical sensitivity of nursing students in Iran.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"209"},"PeriodicalIF":1.6,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12065369/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143954815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Meteorological factors association with under-five children diarrhea incidence in central Gondar zone, Northwest Ethiopia. A time series study.","authors":"Gelila Yitageasu, Hailemariam Feleke, Zewudu Andualem, Lidetu Demoze, Kidist Asrat, Zemichael Gizaw","doi":"10.1186/s13104-025-07270-8","DOIUrl":"https://doi.org/10.1186/s13104-025-07270-8","url":null,"abstract":"<p><strong>Background: </strong>Under 5 children diarrhea has been one of the major public health concerns in countries with limited resources such as Ethiopia. Understanding the association between under-5 diarrhea and meteorological factors will contribute to safeguarding children from adverse health effects through early warning mechanisms. Thus, this study aimed to explore the association between under-5 diarrhea and meteorological factors to reduce health risks.</p><p><strong>Methods: </strong>A time-series ecological study was used to explore the association between meteorological factors and under-5 diarrhea incidence. Spearman's correlation was computed to test the correlation and a negative binomial regression model was fitted to determine the associations of meteorological factors with under-5 diarrhea incidence. The multicollinearity was checked using the variance inflation factor (VIF) before the multivariable regression analysis and the value was 5. aIRRs with 95% CIs and a significance level of 0.05 were used for all the statistical tests. Statistical analyses were conducted using STATA 14.2 software.</p><p><strong>Results: </strong>The highest under-5 diarrhea incidence morbidities was 180.9 per 1000 per year for under-five children. This study revealed a positive and negative correlation between the count of under-5 diarrhea and average monthly temperature and rainfall at 0 and 2 lag months with RRs of 1.0209 (95% CI: 1.0034-1.0387), RR 1.0202(95% CI:1.0022-1.0385), RR 0.999(95% CI:0.9985-0.9996), and RR 0.9992(95% CI:0.9987-0.9997) respectively.</p><p><strong>Conclusion: </strong>There was an association between under 5 diarrhea incidence and meteorological factors in the Central Gondar Zone. The mean monthly temperature and rainfall were positively and negatively related to the incidence of diarrhea in children under 5 years old. The results showed that the observed association between meteorological factors and under-5 diarrhea incidence could be used as evidence for the use of early warning systems for the prevention of childhood diarrhea.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"208"},"PeriodicalIF":1.6,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12063321/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143982015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are AudioviSual maTERials disseminated via sOcIal meDia effective to improve evidence-based rehabilitation implementation for physiotherapists (ASTEROID trial)? A feasibility study.","authors":"Myllena M G Fernandes, Anna Carolina O Machado, Maurício S Fanfa, Ada C M Silveira, Rafaela A Schreiner, Anna Julia Meireles Dangui, Maitê M Pellenz, Daniela Rigo, Luiza Marx Matte, Emilly Renk Mello, Ane Priscila Diel, Brenda D Guterres, Lucas Dos Santos Costa, Bruna Wageck, Inaihá Laureano Benincá, Carolina Holz Nonnenmacher, Nadine Carneiro Tura, Laura Bortolozzo Leitão, Alessandro Haupenthal, Guilherme S Nunes","doi":"10.1186/s13104-025-07259-3","DOIUrl":"https://doi.org/10.1186/s13104-025-07259-3","url":null,"abstract":"<p><strong>Objective: </strong>The present study aimed to evaluate the feasibility of an educational program disseminated via social media to improve the scientific and technical knowledge of physiotherapists.</p><p><strong>Results: </strong>In this single-group interventional feasibility study, practicing physiotherapists participated in a 10-week Instagram-based program, which included 20 infographics posted twice weekly. Feasibility was evaluated using the RE-AIM framework (Reach, Effectiveness, Adoption, Implementation, and Maintenance). After the intervention, semi-structured interviews were conducted to gather feedback on participant experiences. Of the 30 physiotherapists recruited, 15 initiated the program, and 8 (53%) completed it. No significant differences were observed between pre- and post-program scores on effectiveness outcomes related to perceptions, utilization, and understanding of scientific information for clinical practice. While 63% of participants reported that the program helped them overcome barriers to EBP, overall perceptions and behaviors showed minimal change. Nonetheless, all participants recognized a positive impact on their clinical practice, with 50% reporting that they applied program content to their work. Although 63% indicated they would maintain their approach to studying technical content, all participants affirmed their intention to use resources that facilitate knowledge acquisition. Feedback from interviews indicated positive attitudes towards social media-based educational programs.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"207"},"PeriodicalIF":1.6,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12063303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143988729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}