BMC Research Notes最新文献

{"title":"Evaluation of the price-efficacy relationship for multiple brands of ciprofloxacin and gentamicin in Kabul: a cross-sectional study.","authors":"Ahmad Zia Noori, Hashmatullah Yousufi, Haji Mohammad Naimi","doi":"10.1186/s13104-025-07258-4","DOIUrl":"https://doi.org/10.1186/s13104-025-07258-4","url":null,"abstract":"<p><strong>Background: </strong>The quality of consumer products constitutes a prominent issue on a global scale. The proliferation of counterfeit pharmaceuticals poses a significant challenge not only in developing and underdeveloped nations but also represents a considerable concern in developed countries. In Kabul, a major issue is the availability of multiple brands of antibiotics with fluctuating prices. To ascertain the quality and correlation of pricing with the efficacy of antibiotics, an evaluation of their effectiveness is deemed both essential and significant. Ciprofloxacin and Gentamicin are widely utilized antibiotics for treating infections induced by specific strains of Gram-negative and Gram-positive bacteria. The aim of this study was to investigate the relationship between brand price and the efficacy of these antibiotics.</p><p><strong>Methods: </strong>A total of 40 ciprofloxacin 500 mg tablet brands and 15 gentamicin 80 mg ampule brands were procured from pharmacies in Kabul across eight countries. Ten samples from each brands were assessed for efficacy through MIC and MBC assays against Staphylococcus aureus (ATCC 29213), following Clinical and Laboratory Standards Institute protocols. Efficacy data were obtained by inoculating S. aureus suspensions in Mueller-Hinton medium with various concentrations of each antibiotic, incubated at 35-37˚C for 24 h. Following MIC determination, inoculated cultures were plated on Mueller-Hinton agar and incubated at 35-37˚C for 24 h for colony enumeration. Statistical analysis was conducted using ANOVA, Student's t-test, and Pearson correlation via SPSS version 26, with p-values of ≤ 0.05 considered significant.</p><p><strong>Results: </strong>The prices of Ciprofloxacin tablets ranged from 25 to 275 Afghanis (mean = 99.60), while Gentamicin prices varied from 3 to 15 Afghanis (mean = 8.37). Of the 40 ciprofloxacin brands, 6 (15%) were unregistered, and from 15 gentamicin brands, 3 (20%) were unregistered. There was no significant difference in Gentamicin efficacy against S. aureus. However, a significant difference was noted in Ciprofloxacin efficacy against S. aureus (p < 0.01).</p><p><strong>Conclusions: </strong>The results of this study highlight the critical need for stringent quality control and regulatory oversight, especially for unregistered antibiotics, due to the significant variations observed in Ciprofloxacin efficacy (p < 0.01), even though no such difference was noted with Gentamicin. Policymakers should implement regulations to ensure all antibiotic brands adhere to quality standards, while pharmacists and healthcare professionals should prioritize using registered, effective medications to safeguard public health.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"189"},"PeriodicalIF":1.6,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12016291/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nursing students' attitudes toward cross-gender care: a cross-sectional study.","authors":"Saumya P Srivastava, Soni Chauhan, Anuj Singh, Surya Kant Tiwari, Surat Ram Kudi, Anchal Gupta","doi":"10.1186/s13104-025-07254-8","DOIUrl":"https://doi.org/10.1186/s13104-025-07254-8","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to assess nursing students' attitudes toward providing cross-gender care and to identify the factors influencing these attitudes.</p><p><strong>Results: </strong>A cross-sectional study of 338 nursing students in Northern India found that over half (50.9%) had unfavorable attitudes towards cross-gender care. Female students demonstrated significantly more positive attitudes than male students (p < 0.01). Multiple regression analysis identified gender (β = 0.246, p < 0.001), academic year (β=-0.150, p = 0.009), and prior experience with cross-gender care (β = 0.100, p = 0.048) as significant predictors of attitudes. The regression model explained 19.9% of the variance in attitudes (R²=0.199, p < 0.001). Male students expressed concerns about providing quality physical care and emotional support for patients and felt inadequately prepared to provide physical and emotional support to opposite-gender patients. These findings highlight the need for enhanced gender-sensitive training in nursing education to improve attitudes and competencies in cross-gender care provision.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"191"},"PeriodicalIF":1.6,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020158/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143980798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Food and nutrition security of adolescents and young adults NEETs and non-NEETs in two low socioeconomic urban settlements in South Africa.","authors":"Sicelosethu S Siro, Nazeeia Sayed, Elizabeth Catherina Swart","doi":"10.1186/s13104-025-07257-5","DOIUrl":"https://doi.org/10.1186/s13104-025-07257-5","url":null,"abstract":"<p><strong>Introduction: </strong>Adolescents and young adults not yet in employment, education, or training (NEETs) account for a sizable fraction of the global population. In South Africa, 34.3% of young individuals aged 15 to 24 were classified as NEETs in 2022. Lack of work in low-income areas may lead to poverty and food insecurity, negatively impacting diet quality.</p><p><strong>Objective: </strong>This cross-sectional study aimed to evaluate and compare the anthropometric status, dietary intake, and food security of NEET and non-NEET adolescents and young adults (aged 18-24 years) in Langa and Fisantekraal, two low socioeconomic settlements in South Africa.</p><p><strong>Methods: </strong>Participants were recruited through door-to-door visits. Standardized instruments including a socio-demographic questionnaire, household hunger score, lived poverty index, anthropometric assessments, and 24-hour dietary recalls were used for data collection.</p><p><strong>Results: </strong>There were no significant differences in the prevalence of household hunger (p = 0.496), the lived poverty index (p = 0.111) and the prevalence of low micronutrient intakes between the NEETS and non-NEETs (p > 0.05). The prevalence of inadequate daily iron intake had the lowest prevalence while the prevalence of inadequate calcium intake was highest in this group of adolescents and young adults. The insufficient intake of micronutrients among adolescents and young adults can be attributed to the diets consumed by this demographic group.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"187"},"PeriodicalIF":1.6,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12016356/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143965854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimization of mucilage secretion of Plantago ovata, Alyssum desertorum, and Ocimum basilicum seeds by response surface method.","authors":"Bahram Tafaghodinia","doi":"10.1186/s13104-023-06517-6","DOIUrl":"https://doi.org/10.1186/s13104-023-06517-6","url":null,"abstract":"<p><p>Diaspore comprises a collection of seed coats and other organ components that effectively protect the embryo and dispersal. The mucilage in many species, a gelatinous mixture of cell wall polysaccharides, is secreted by the pericarp. Although the modification, synthesis, and secretion of the strain of mucilage as well as structure and roles of plant cell wall have been of great interest and study by researchers, the understanding of the best conditions for the secretion of mucilage has received low attention. This research aimed to investigate effective factors in the process of mucilage secretion in P. ovata, A. desertorum, and O. basilicum seeds. To achieve this objective, an investigation was conducted to examine the impact of seed number, polarity, pH and species on mucilage secretion. This study showed that the number of seeds and type of species had the least and the most effect on mucilage production, respectively. Finally, according to the results of Response Surface Method design experiments, pH, polarity and species had a significant effect on the process of mucilage secretion. pH = 4 and polarity = 15 for P. ovata and pH = 10 and polarity = 15 for O. basilicum and A. desertorum were the most favorable conditions for secretion of 10.3 mm, 9.4 mm, and 2.9 mm of mucilage, respectively.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"188"},"PeriodicalIF":1.6,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12016475/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143973887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The accuracy of digital impression with different intraoral scanners on maxillary all on four implants: an in vitro study.","authors":"Hesham M El-Refay, Medhat Sameh Abdelaziz, Nora M Cheta, Mohamed F Abdallah","doi":"10.1186/s13104-025-07235-x","DOIUrl":"https://doi.org/10.1186/s13104-025-07235-x","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to evaluate the effect of 30° angulation of (All-on-four) implants on the accuracy of digital impressions using different intra-oral scanners in the maxillary edentulous arch in terms of trueness and precision.</p><p><strong>Materials and methods: </strong>A maxillary completely edentulous model was 3D printed with four-cylinder holes measuring 4.3*10 mm, creating space for implant analogs at the canines and second premolar areas. The two anterior implants were placed parallel to each other with 0-degree angulation at the site of the canines, while the two posterior implants were placed at the site of the second premolars with 30° distal angulations. Four peek scan bodies were screwed to analogs. The model is scanned using an EOS X5 desktop scanner and set as a reference model. Afterward, three groups of intraoral scanners group 1 (Trios3shape), group 2 (Medit I700), and group 3 (Launca DL-202) were used to scan the model. Seven scans of the model were performed for each scanner following the manufacturer protocol. The trueness and precision of each intraoral scanner were virtually tested using the Gemoagic Control X software program.</p><p><strong>Results: </strong>Regarding trueness, there was a statistically significant deviation between the three intraoral scanners recording 38, 44, and 229 μm for the Trios, Medit I-700, and Launca scanners, respectively, while there was no statistically significant difference in precision between the Trios and Medit I700 scanners.</p><p><strong>Conclusions: </strong>The Trios scanner was the most accurate regarding trueness and precision for recording the maxillary full arch implants, followed by the Medit I-700, and the Launca scanner due to the ability of the Trios scanner to scan the posterior angulated implants as accurately as the anterior straight ones. Also, the scanner technology separately doesn't affect scanning accuracy, but other factors should be taken into consideration such as scanner design and scanner head size.</p><p><strong>Clinical relevance: </strong>The type of intraoral scanner used in full arch cases greatly affects the accuracy of digital impressions, which may affect the fit of future prostheses, so the operator should carefully choose the proper optical scanner.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"186"},"PeriodicalIF":1.6,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12013090/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In vitro RNA-mediated gene silencing of Fusarium oxysporum f.sp. cubense from Ecuador and assessment of RNAi molecule stability in banana plants.","authors":"Ricardo Pacheco, Julio Bonilla, Aracely Paguay, Freddy Magdama, Pablo Chong","doi":"10.1186/s13104-025-07253-9","DOIUrl":"https://doi.org/10.1186/s13104-025-07253-9","url":null,"abstract":"<p><strong>Objective: </strong>Fusarium wilt poses a significant threat to banana production, caused by diverse clonal Fusarium lineages. Given the lack of curative measures, developing effective treatments is crucial. RNA interference (RNAi) technology, utilizing double-stranded RNA (dsRNA) molecules, offers a promising solution. In this study, RNAi was evaluated by silencing the activity of the Beta-tubulin (Focβ-tub), C5 Sterol desaturase (FocERG3) and Chitin synthase 1 (FocChs1) genes in a pathogenic Fusarium strain. Furthermore, we study the potential of dsRNA translocation in 3 months old banana plants at early hours of been spray under greenhouse conditions.</p><p><strong>Results: </strong>In vitro results demonstrated that dsRNA-FocChs1 was more effective in inhibiting spores, with an average IC₅₀ of 156.84 mg/L, compared to dsRNA-Focβ-tub (IC₅₀: 532.7 mg/L), dsRNA-FocERG3 (IC₅₀: 635.59 mg/L), and a positive control (IC₅₀: 243.91 mg/L). A greenhouse test was conducted to evaluate the translocation of dsRNA in banana plants. The results demonstrated that the dsRNA remained on the applied leaf without degradation up to 48 h post-application (hpa). However, no translocation to other plant tissues was detected until the last time point. Further time points should be evaluated to ascertain the dsRNA translocation to other banana plant tissue.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"185"},"PeriodicalIF":1.6,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12013083/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143981310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing professional development in medical residency through a shadow curriculum: an evaluation based on Kirkpatrick model.","authors":"Sahba Fekri, Amin Habibi, Hamed Khani, Samane Babaei, Masomeh Kalantarion","doi":"10.1186/s13104-025-07233-z","DOIUrl":"https://doi.org/10.1186/s13104-025-07233-z","url":null,"abstract":"<p><strong>Introduction: </strong>Current medical residency programs often neglect critical areas of professional development, such as patient safety, stewardship, and effective clinical documentation. This study evaluates the effectiveness of a shadow curriculum designed to enhance these aspects for medical residents.</p><p><strong>Methods: </strong>The shadow curriculum was implemented for first-year residents in ophthalmology, internal medicine, and urology, consisting of an 8-hour workshop covering job encounters, stewardship, patient safety principles, medical documentation, and electronic prescribing. Conducted in 2023 with 22 residents, the evaluation utilized questionnaires, pre- and post-tests, and semi-structured interviews to assess satisfaction and learning outcomes.</p><p><strong>Results: </strong>54.55% of participants with a mean score of 23.66 (SD = 1.97) reported satisfaction with course content, and 63.63% with a mean score of 22.64 (SD = 2.63), were satisfied with the course organization. Pre/post-test results showed a significant knowledge increase (p < 0.001), particularly in antibiotic prescribing and patient safety. Qualitative interviews emphasized on three themes including consumer oriented learning, changing the perspective of teaching and learning, and promotion of self-directed learning.</p><p><strong>Conclusions: </strong>This study highlights the shadow curriculum's effectiveness in improving residents' professional satisfaction and knowledge. By prioritizing learner perspectives and extending opportunities beyond traditional settings, it fosters a personalized learning environment. These findings underscore the need to integrate shadow curricula into medical training to meet evolving educational needs and enhance professional development.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"184"},"PeriodicalIF":1.6,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12009517/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143981476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics of type 2 diabetes patients with overt cardiovascular diseases in Malaysia: the real-world evidence from the National Diabetes Registry.","authors":"Kim Sui Wan, Noran Naqiah Hairi, Feisul Mustapha, Muhammad Fadhli Mohd Yusoff, Mastura Ismail, Foong Ming Moy, Noor Ani Ahmad","doi":"10.1186/s13104-025-07204-4","DOIUrl":"https://doi.org/10.1186/s13104-025-07204-4","url":null,"abstract":"<p><strong>Objective: </strong>The characteristics of diabetes patients with cardiovascular disease (CVD) in Malaysia are not well understood, especially in terms of metabolic control and treatment profiles. We aimed to determine the characteristics of type 2 diabetes patients with CVD in public primary care clinics in Malaysia. A cross-sectional analysis of the baseline information of an established retrospective cohort dataset was done.</p><p><strong>Results: </strong>Among 18,312 patients, 4.1% had CVD. In the multiple logistic regression model, CVD was associated with males, older age, longer diabetes duration, hypertension, dyslipidaemia, nephropathy, insulin, antiplatelet agents, and glycosylated haemoglobin A1c control. In contrast, LDL cholesterol control was less common among patients with CVD. The percentage of patients with CVD who achieved the recommended glycosylated haemoglobin A1c ≤ 8%, blood pressure ≤ 135/75 mmHg, and LDL cholesterol < 1.8 mmol/L were 59.5%, 25.3%, and 13.7%, respectively. Meanwhile, 44.7%, 25.6%, and 42.7% of patients without CVD achieved glycosylated haemoglobin A1c ≤ 7.0%, blood pressure ≤ 135/75 mmHg, and LDL cholesterol ≤ 2.6 mmol/L, respectively. Many patients did not achieve the recommended treatment targets. There are ample opportunities to optimise the quality of diabetes management in primary care settings in Malaysia.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"183"},"PeriodicalIF":1.6,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12007231/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of atherogenic indices and triglyceride-total cholesterol-body weight index (TCBI) with severity of stenosis in patients undergoing angiography: a case-control study.","authors":"Mobina Imannezhad, Farzam Kamrani, Ali Shariatikia, Mahsa Nasrollahi, Hanie Mahaki, Ali Rezaee, Mohsen Moohebati, Seyed Hamed Hashemi Shahri, Susan Darroudi","doi":"10.1186/s13104-025-07203-5","DOIUrl":"https://doi.org/10.1186/s13104-025-07203-5","url":null,"abstract":"<p><strong>Objectives: </strong>Coronary artery disease, caused by atherosclerosis, necessitates assessing plaque formation risk using indices like the atherogenic index of plasma (AIP), Castelli's risk indexes (CRI-I and CRI-II), the atherogenic coefficient (AC), and the triglyceride-total cholesterol-body weight index (TCBI). Although TCBI primarily assesses mortality risk, its relationship with stenosis severity is unclear. Utilizing data from a prior study, a case-control analysis was conducted on 1,187 subjects, which included 781 patients who underwent coronary angiography and 406 healthy controls. The indices were compared across varying degrees of arterial blockages.</p><p><strong>Results: </strong>AIP significantly correlated with stenosis severity in women, increasing the risk of three-vessel stenosis by 2.5 times. AC raised the risk of single-vessel stenosis in men by 2.7 times. CRI-I and CRI-II showed a positive relationship with arterial stenosis in women, with CRI-I increasing the risk of two and three-vessel blockages by 21.9% and 22.4%, respectively. A one-unit increase in CRI-II raised the risk by 33.1% for two arteries and 25.3% for three. In conclusion, AIP, CRI-I, and CRI-II in women, along with AC in men, correlated with arterial stenosis severity, while TCBI did not. Further research is needed to determine which index is most effective in predicting CAD risk.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"180"},"PeriodicalIF":1.6,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12004764/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143977572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Informing research design through patient and public involvement; patients and carers with lived experience post-hospital discharge and potential roles for general practice pharmacists.","authors":"Faiza Yahya, Sam Bartlett, Vibhu Paudyal, Muhammad Abdul Hadi, Hamde Nazar, Ian Maidment","doi":"10.1186/s13104-025-07248-6","DOIUrl":"https://doi.org/10.1186/s13104-025-07248-6","url":null,"abstract":"<p><strong>Background: </strong>Medication safety across care transitions remains a significant burden on healthcare systems. Patient and Public Involvement (PPI) is useful at the very early stages of intervention development to inform research priorities. The aim of this PPI was to scope patients' and carers' lived experiences of medicines management post-hospital discharge to inform the design of a research proposal.</p><p><strong>Methods: </strong>A research planning PPI workshop and additional one-to-one discussions were undertaken with patients and informal carers who had experienced a recent discharge from hospital and were prescribed regular repeat medications.</p><p><strong>Results: </strong>The 12 public contributors identified that the priority for patients was not limited to medication management alone but rather a broader care package. Multiple themes as priorities for research emerged: (1) broader holistic and social aspects of care involving various healthcare professionals, (2) practical aspects such as timeliness of follow-up and co-ordination of medication management, and (3) communication with the patient/carer and information transfer between settings.</p><p><strong>Conclusion: </strong>Valuable insights from this PPI helped inform future research design priorities and identify the need for a more holistic approach to care. Future work with multi-stakeholder engagement involving different professionals across sectors is needed to explore safer integrated transitions of care, as well as the use of ongoing PPI and co-design, considering populations that are most vulnerable.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"181"},"PeriodicalIF":1.6,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12007321/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143975891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}