BMC Research Notes最新文献

Swedish version of the Pregnancy Physical Activity Questionnaire (PPAQ-SWE), translation and cultural adaptation.

IF 1.6

BMC Research Notes Pub Date : 2025-02-07 DOI: 10.1186/s13104-025-07135-0

Annika Svahn Ekdahl, Viana Mikkelsen, Heléna Frenell, Qarin Lood, Theresa Westgård, Joanne M Fuller, Andrea Mikkelsen, Annelie Gutke

{"title":"Swedish version of the Pregnancy Physical Activity Questionnaire (PPAQ-SWE), translation and cultural adaptation.","authors":"Annika Svahn Ekdahl, Viana Mikkelsen, Heléna Frenell, Qarin Lood, Theresa Westgård, Joanne M Fuller, Andrea Mikkelsen, Annelie Gutke","doi":"10.1186/s13104-025-07135-0","DOIUrl":"10.1186/s13104-025-07135-0","url":null,"abstract":"Objective: Physical activity has well-known health benefits in all stages of life and may also reduce the risk for pregnancy-related complications, but many pregnant women do not reach the recommended activity levels. Tailored advice is often provided by healthcare professionals to promote physical activity during pregnancy. To provide such advice, assessment of the actual level of physical activity is necessary, but there are currently no standardized methods for this. The Pregnancy Physical Activity Questionnaire (PPAQ) is a self-administered instrument, designed to determine physical activity during pregnancy but a Swedish version of the questionnaire is not yet available.Result: The PPAQ was translated and culturally adapted into a Swedish version, i.e., PPAQ-SWE according to the process described by Beaton et al. Several minor linguistic adjustments were needed, that mainly concerned semantic and cultural adaptations, such as adding, removing, or replacing words to match Swedish cultural aspects. For instance, \"gestational week\" was used instead of \"trimester,\" and \"older person\" replaced \"older adult.\" The reference to a \"1-gallon milk jug\" was replaced with \"3-4 liters of milk\" to fit the metric system used in Sweden. Two questions regarding bicycling, a common form of transportation in Sweden, and one free-text comment option was added.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"58"},"PeriodicalIF":1.6,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143370434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The relationship between the intake of fruits, vegetables, and dairy products and dyslipidemia in STEPs study.

IF 1.6

BMC Research Notes Pub Date : 2025-02-07 DOI: 10.1186/s13104-025-07132-3

Mehran Nouri, Zohreh Ebrahimi, Zainab Shateri, Shiva Faghih

引用次数: 0

Correction: The impact of the physicochemical properties of calcium phosphate ceramics on biocompatibility and osteogenic differentiation of mesenchymal stem cells.

IF 1.6

BMC Research Notes Pub Date : 2025-02-06 DOI: 10.1186/s13104-025-07127-0

Yuliia Skliarenko, Volodymyr V Kolomiiets, Volodymyr V Balatskyi, Yuliia Galuza, Oksana S Koryak, Larysa L Macewicz, Tetiana P Ruban, Sergey A Firstov, Nataliia V Ulianchych, Oksana O Piven

引用次数: 0

Climate catastrophe in Rio Grande do sul, Brazil: impact of strategic actions in response to flooding.

IF 1.6

BMC Research Notes Pub Date : 2025-02-06 DOI: 10.1186/s13104-025-07094-6

Priscila Bárbara Zanini Rosa, Giovana Munhoz de Oliveira, Monique Pimentel, Melina Schuch, Jonas Wolf

{"title":"Climate catastrophe in Rio Grande do sul, Brazil: impact of strategic actions in response to flooding.","authors":"Priscila Bárbara Zanini Rosa, Giovana Munhoz de Oliveira, Monique Pimentel, Melina Schuch, Jonas Wolf","doi":"10.1186/s13104-025-07094-6","DOIUrl":"10.1186/s13104-025-07094-6","url":null,"abstract":"Objective: In May 2024, Rio Grande do Sul, Brazil, faced the greatest climate catastrophe in its history when a flood affected approximately 90% of the entire state territory. This study aimed to describe the strategic actions of volunteers gathered by a social institution linked to a private hospital in southern Brazil and their impacts on the affected community.Methods: Descriptive study, based on the experience of the team at the Instituto Moinhos Social (IMS) - Hospital Moinhos de Vento (Rio Grande do Sul - Brazil), which brought together a group of volunteers to develop actions in response to the flood. Between 05/01/2024 and 07/31/2024, the IMS organized donations of basic items, health care, and monetary donations to recover goods for people affected by the flood.Results description: The IMS had 583 volunteers working in the phase of receiving, organizing, and distributing donations and 208 health professionals for emergency care, mental health, and telemedicine. In total, approximately 317 thousand basic items were organized and distributed, which benefited almost 100 thousand people; 1044 people received health care; and 490 families received vouchers worth R$2,500 (US$455,66) for the recovery of material goods.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"56"},"PeriodicalIF":1.6,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143363742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Real-time multimodal imaging of daptomycin action on the cell wall of adherent Staphylococcus aureus.

IF 1.6

BMC Research Notes Pub Date : 2025-02-05 DOI: 10.1186/s13104-025-07130-5

Alexis Canette, Rym Boudjemaa, Julien Deschamps, Karine Steenkeste, Christian Marlière, Romain Briandet, Marie-Pierre Fontaine-Aupart

{"title":"Real-time multimodal imaging of daptomycin action on the cell wall of adherent Staphylococcus aureus.","authors":"Alexis Canette, Rym Boudjemaa, Julien Deschamps, Karine Steenkeste, Christian Marlière, Romain Briandet, Marie-Pierre Fontaine-Aupart","doi":"10.1186/s13104-025-07130-5","DOIUrl":"10.1186/s13104-025-07130-5","url":null,"abstract":"Objectives: This study investigated the efficacy of daptomycin against adherent Staphylococcus aureus (S. aureus), a common colonizer of medical devices that leads to severe infections. For the first time, we evaluated the bactericidal effects of daptomycin on S. aureus immediately after adhesion, mimicking early-stage contamination of biomaterials. Time-kill curve assay and confocal laser scanning microscopy (CLSM) were used to analyze the process dynamics. In addition, atomic force microscopy (AFM) and scanning electron microscopy (SEM) were employed to elucidate daptomycin-induced structural changes in the bacterial cell wall.Results description: Daptomycin, at clinically relevant concentrations, rapidly eradicated adherent bacteria in the exponential growth phase, demonstrating an efficiency comparable to its action against planktonic cells. Prolonged exposure to the antibiotic caused marked alterations in the bacterial cell wall, including surface roughening and perforation, as revealed by multimodal imaging. However, daptomycin effectiveness diminished as biofilm formation progressed, underscoring the need for further exploration of optimized clinical strategies.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"54"},"PeriodicalIF":1.6,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11796211/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143254839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pilot application of an inflammation and physiological dysregulation index based on noninvasive salivary biomarkers.

IF 1.6

BMC Research Notes Pub Date : 2025-02-05 DOI: 10.1186/s13104-024-07056-4

Andrey I Egorov, William Xue, Jason Kobylanski, Miyu Fuzawa, Shannon M Griffin, Timothy J Wade, Michael Nye

{"title":"Pilot application of an inflammation and physiological dysregulation index based on noninvasive salivary biomarkers.","authors":"Andrey I Egorov, William Xue, Jason Kobylanski, Miyu Fuzawa, Shannon M Griffin, Timothy J Wade, Michael Nye","doi":"10.1186/s13104-024-07056-4","DOIUrl":"10.1186/s13104-024-07056-4","url":null,"abstract":"Background and objective: Noninvasive salivary biomarkers can be used to assess the cumulative subclinical health impacts of social and environmental stressors. We evaluated seven salivary biomarkers of neuroendocrine and immune functions and a group index of physiological dysregulation based on these biomarkers in a pilot survey in a socioeconomically disadvantaged population.Results: Participants recruited at subsidized public housing projects in Denver, Colorado, completed a sociodemographic, behavioral, and health questionnaire and used passive drool samplers to collect five saliva samples over the course of 1 day. Samples were tested for the neuroendocrine biomarkers alpha-amylase, cortisol, and dehydroepiandrosterone (DHEA) as well as immune system/inflammation biomarkers C-reactive protein (CRP), interleukin (IL)-1β, IL-6 and total immunoglobulin A (IgA). A composite Inflammation and Physiological Dysregulation Index (IPDI) was calculated as a count of potentially unhealthy values of dichotomized biomarkers. In 20 individuals who completed the survey (average age 46 years, 75% females), allergy to house dust was significantly associated with increased IPDI (adjusted for age) and significantly increased odds of potentially unhealthy values of total IgA, IL-1β, and CRP. Age, obesity, diabetes, allergy to pollen, recent loss of employment, and depression, anxiety, and stress scores from the standard DASS-21 questionnaire were positively but not significantly (0.05 ","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"53"},"PeriodicalIF":1.6,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11796071/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143254838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

OsHMA3 overexpression works more efficiently in generating low-Cd rice grain than OsNramp5 knockout mutation.

IF 1.6

BMC Research Notes Pub Date : 2025-02-05 DOI: 10.1186/s13104-025-07112-7

Yuejing Gui, Joanne Teo, Dongsheng Tian, Raji Mohan, Zhongchao Yin

{"title":"OsHMA3 overexpression works more efficiently in generating low-Cd rice grain than OsNramp5 knockout mutation.","authors":"Yuejing Gui, Joanne Teo, Dongsheng Tian, Raji Mohan, Zhongchao Yin","doi":"10.1186/s13104-025-07112-7","DOIUrl":"10.1186/s13104-025-07112-7","url":null,"abstract":"Objective: Cadmium (Cd) is a highly toxic metal element and a carcinogen to humans. Rice is prone to taking up Cd from paddy fields and accumulating it in grain, which raises health concerns for rice consumers. OsNramp5 is a major transporter for Cd and manganese (Mn) uptake in rice, whereas OsHMA3 is a tonoplast-localized transporter involved in Cd detoxification in vacuoles. In this study, we compared the efficiency of OsNramp5 knockout mutation and OsHMA3 overexpression in reducing Cd content in rice grain.Results: The grain Cd content of the OsNramp5 knockout mutants was significantly lower than that of the wild-type rice T5105. However, these mutants still had much higher grain Cd content than the previously reported OsNramp5 mutants or the OsHMA3 overexpression lines developed in our previous study. Pyramiding the OsNramp5 mutant allele and the OsHMA3 transgene in a single line did not result in an additional reduction in grain Cd content. The OsNramp5 gene in T5105 has a haplotype II promoter, and its knockout mutation also partially reduced Mn content in rice grain. Our results demonstrate that OsHMA3 overexpression works more efficiently in generating low-Cd rice grain than OsNramp5 knockout mutation without affecting Mn uptake in rice.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"55"},"PeriodicalIF":1.6,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11800450/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143254837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tympanoplasty in Northern Ethiopia: success rates, failure factors, and audiometric improvements.

IF 1.6

BMC Research Notes Pub Date : 2025-02-03 DOI: 10.1186/s13104-025-07123-4

Filmawit Gebremeskel Asfaha, Bethelhem Birhanu Tesfa, Lemlem Weldegerima Gebremariam, Andom Geremew, Seid Temam, Girmatsion Fisseha Abreha

{"title":"Tympanoplasty in Northern Ethiopia: success rates, failure factors, and audiometric improvements.","authors":"Filmawit Gebremeskel Asfaha, Bethelhem Birhanu Tesfa, Lemlem Weldegerima Gebremariam, Andom Geremew, Seid Temam, Girmatsion Fisseha Abreha","doi":"10.1186/s13104-025-07123-4","DOIUrl":"10.1186/s13104-025-07123-4","url":null,"abstract":"Objective: This study aimed to determine the success rate of tympanoplasty, the factors associated with failure rate, and audiometric gains after the surgical procedure in Ethiopia.Results: There were 82 successful grafts take out of the 92 tympanoplasty procedures with an overall success rate of 89.1%. Females, who had tympanoplasty had 45 (91.8%) successful grafts while 37 (86.0%) successful grafts for male. Of the total tympanoplasties, 50(53.4%) of it were done in the left ear. Ear discharge was found to be a significant predictor of tympanoplasty failure rate [AOR = 9.6, 95% CI (1.1 - 88.8)]. There was a significant gain of air conduction with a p-value of < 0.001 after the tympanoplasty procedure which was about 13 dB mean difference.Conclusions: In this study, only post-operative ear infection was found to decrease the success rate of tympanoplasty significantly. It also revealed that tympanoplasty improves hearing ability. We recommend a strict application of infection prevention and control strategies, and adequate and comprehensive follow-up of patients including audiometric assessment.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"52"},"PeriodicalIF":1.6,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11792363/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143122146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Severe anaemia in people with HIV: demographic, clinical and renal correlates. 艾滋病病毒感染者的严重贫血：人口、临床和肾脏相关性。

IF 1.6

BMC Research Notes Pub Date : 2025-02-03 DOI: 10.1186/s13104-025-07100-x

Kingsley Kamvuma, Sody Munsaka, Sepiso K Masenga, John Amos Mulemena, Christopher Newton Phiri, Michelo Miyoba, Benson M Hamooya

{"title":"Severe anaemia in people with HIV: demographic, clinical and renal correlates.","authors":"Kingsley Kamvuma, Sody Munsaka, Sepiso K Masenga, John Amos Mulemena, Christopher Newton Phiri, Michelo Miyoba, Benson M Hamooya","doi":"10.1186/s13104-025-07100-x","DOIUrl":"10.1186/s13104-025-07100-x","url":null,"abstract":"Objective: This study aimed to investigate the sociodemographic, clinical and renal correlates associated with severe anaemia among people with HIV.Methods: We conducted a cross-sectional analysis of people with HIV on antiretroviral therapy (ART) for at least 6 months, stratified by anaemia status. Anaemia was defined based on the World Health Organisation (WHO) classification, as haemoglobin concentration lower than normal i.e. <12 g/dl in females and < 13 g/dl in males and the primary outcome, severe anaemia, as a haemoglobin level below 8 g/dl according to the World Health Organisation.Results: The study comprised 372 participants receiving ART, of whom 236 (63.4%) were females. The mean age ± SD of the participants was 44.8 ± 12.4 years. The overall prevalence of severe anaemia was 7.8% (95% CI: 0.053-0.111). In multivariable logistic regression analysis, factors significantly associated with severe anaemia were female sex (Adjusted Odds Ratio (AOR: 14.3, 95% CI: 2.14-126.6), albumin (AOR: 0.93 95% CI: 0.88-0.98) and creatinine levels (AOR: 1.01 95% CI: 1.00-1.03).","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"51"},"PeriodicalIF":1.6,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11792207/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143122042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Open challenges for the automatic synthesis of clinical trials.

IF 1.6

BMC Research Notes Pub Date : 2025-02-02 DOI: 10.1186/s13104-025-07121-6

Olivia Sanchez-Graillet, David M Schmidt, Christian Kullik, Philipp Cimiano

{"title":"Open challenges for the automatic synthesis of clinical trials.","authors":"Olivia Sanchez-Graillet, David M Schmidt, Christian Kullik, Philipp Cimiano","doi":"10.1186/s13104-025-07121-6","DOIUrl":"10.1186/s13104-025-07121-6","url":null,"abstract":"Objective: An important criterion for selecting clinical trials to be compared in systematic reviews and meta-analyses is that they measure the same outcomes. However, this represents a challenge as there is a wide variety of outcomes, and it is difficult to standardize them for comparing clinical trials containing them. To address this challenge, we utilized our annotated dataset, which includes 211 abstracts of clinical trials related to glaucoma and type 2 diabetes mellitus. We then developed a tool that provides an overview of the annotated clinical trial information and enables users to group them by outcomes.Results: Using our visualization tool, we formed groups of outcomes and their respective clinical trials. We were able to determine the most common outcomes in clinical trials for these diseases. As a case study on diabetes, we compared our outcomes with those consented by diabetes stakeholders and found that many of the grouped outcomes are aligned with the consented ones. This demonstrates that tools such as the one presented can help standardize clinical outcomes, which in turn help in the synthesis of clinical trials. Finally, we also offer some recommendations that could help in the automation of clinical trials based on outcome standardization.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"50"},"PeriodicalIF":1.6,"publicationDate":"2025-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11789334/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0