BMC Research Notes最新文献

Assessment of mosquito larval source management practices for malaria elimination in South West Ethiopia people regional state: a mixed study design approach. 评估埃塞俄比亚西南部地区消除疟疾的蚊幼虫源管理做法：一种混合研究设计方法。

IF 1.6

BMC Research Notes Pub Date : 2025-07-03 DOI: 10.1186/s13104-025-07349-2

Bezuayehu Alemayehu, Tadesse Gebremedhin, Mathewos Alemu Gebremichael, Wondwossen Niguse, Girma Mamo Zegene, Ephrem Negeri, Ibrahim Temam, Haile Zewude, Tamerat Bogale, Endale Sahile, Erkyehun Pawlos Shash

{"title":"Assessment of mosquito larval source management practices for malaria elimination in South West Ethiopia people regional state: a mixed study design approach.","authors":"Bezuayehu Alemayehu, Tadesse Gebremedhin, Mathewos Alemu Gebremichael, Wondwossen Niguse, Girma Mamo Zegene, Ephrem Negeri, Ibrahim Temam, Haile Zewude, Tamerat Bogale, Endale Sahile, Erkyehun Pawlos Shash","doi":"10.1186/s13104-025-07349-2","DOIUrl":"10.1186/s13104-025-07349-2","url":null,"abstract":"Objective: Malaria is the most significant public health challenge. This study aimed to assess the status of the mosquito LMS practices for malaria elimination in South West Ethiopia. A mixed study designs were used to collect data with pre-tested questionnaires. The data were analyzed on a logistic regression model. Qualitative data were analyzed using Quirkos and results were presented in a thematic.Results: About 19.20% of households had good practice of LSM practice. The majority, 80.09% of households, had poor practices of LSM among a total of 1,552 households. More than half, 58.1% of households had a favorable attitude toward the LSM practice. Those participants with good knowledge of LSM practices had significantly 3.49 times higher odds of engaging in LSM practices compared to those with poor knowledge. Similarly, households with good knowledge of malaria had significantly 8.01 times higher odds of good LSM practices. Residents with favorable attitudes towards LSM practices had statistically 2.58 times higher odds of engaging in good LSM practices, but there were barriers to LSM practices.Conclusions: There are poor LSM practices for malaria elimination that need behavioral change communications and promoting LSM, and providing training on changing attitudes, for prompt intervention, to reduce mosquitoes.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"272"},"PeriodicalIF":1.6,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12225124/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144552364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring food and nutrition security perspectives among high school adolescents in Machakel District, Amhara Region, Ethiopia: a qualitative study. 探讨埃塞俄比亚阿姆哈拉地区马查克尔地区高中青少年的粮食和营养安全观点：一项定性研究。

IF 1.6

BMC Research Notes Pub Date : 2025-07-03 DOI: 10.1186/s13104-025-07340-x

Matyas Atnafu Alehegn, Mogessie Ashenafi, Mesay Mulugeta, Nigatu Regassa

{"title":"Exploring food and nutrition security perspectives among high school adolescents in Machakel District, Amhara Region, Ethiopia: a qualitative study.","authors":"Matyas Atnafu Alehegn, Mogessie Ashenafi, Mesay Mulugeta, Nigatu Regassa","doi":"10.1186/s13104-025-07340-x","DOIUrl":"https://doi.org/10.1186/s13104-025-07340-x","url":null,"abstract":"Objective: This study aimed to understand adolescents' contextual perspectives on nutrition, food security, causes of food insecurity, and the association between food adequacy and academic performance. It explored food and nutrition security among high school adolescents in Machakel District, Amhara Region, Ethiopia. The objective was to explore how food and nutrition security impact adolescents' growth and development. Qualitative data were collected through interviews with 33 key informants including school adolescents, teachers, health workers, community members, and woreda officers and six focus group discussions across four high schools. Data were analysed using MAXQDA Pro 2020 for its user-friendliness and advanced features.Results: Findings showed that school adolescents living away from their families faced challenges in accessing adequate food, both in quantity and variety. These school adolescents relied on various strategies to access food, including part-time work and support from friends, relatives, or the school community, to supplement their food access. Participants perceived that inadequate food access negatively affected school adolescents' academic performance. The study explored the need for interventions to improve adolescent food and nutrition security, including nutrition education programs, funding for nutritious school meals, and collaboration between schools and local communities to support adolescents living away from families.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"273"},"PeriodicalIF":1.6,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144559215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genotyping from targeted NGS data based on a small set of SNPs correctly matches patient samples. 基于一小组snp的靶向NGS数据的基因分型正确匹配患者样本。

IF 1.6

BMC Research Notes Pub Date : 2025-07-02 DOI: 10.1186/s13104-025-07348-3

Deyan Yordanov Yosifov, Christof Schneider, Stephan Stilgenbauer, Daniel Mertens, Eugen Tausch

{"title":"Genotyping from targeted NGS data based on a small set of SNPs correctly matches patient samples.","authors":"Deyan Yordanov Yosifov, Christof Schneider, Stephan Stilgenbauer, Daniel Mertens, Eugen Tausch","doi":"10.1186/s13104-025-07348-3","DOIUrl":"10.1186/s13104-025-07348-3","url":null,"abstract":"Objective: Mislabelling and swapping of laboratory samples are handling errors that can lead to erroneous interpretation of data and/or patient harm. Sequenced samples can be traced back to the respective donors by matching of single nucleotide polymorphisms (SNPs). Frameworks and software to do this have been developed for use with whole genome/exome sequencing data but not for targeted next-generation sequencing (tNGS), possibly due to the limited genomic coverage with tNGS and the need for individualization of the set of interrogated SNPs. We decided to adapt a popular tool for use with tNGS data, to demonstrate the possibility of selecting informative SNPs from a typical tNGS panel and to create an automated workflow for detection of sample handling errors.Results: We compiled a custom list of 28 SNPs and with its help we demonstrated the practicability of using only tNGS data to cost-effectively detect mislabelled samples. In two cohorts of totally 1441 patients with sequential samples, we could identify 3 sample swaps, 7 mislabelled samples (3 externally and 4 internally) and 1 mistake of unknown origin. We provide an R function for automated detection of sample swaps and mislabelling to the community as a free and open-source tool.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"270"},"PeriodicalIF":1.6,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12225085/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144552366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical reasoning education: evaluating the effect of script strategy and reflective practice on nursing students' reasoning development. 临床推理教育：评价剧本策略与反思性实践对护生推理发展的影响。

IF 1.6

BMC Research Notes Pub Date : 2025-07-02 DOI: 10.1186/s13104-025-07338-5

Fatemeh Bahramnezhad, Fatemeh Keshmiri

{"title":"Clinical reasoning education: evaluating the effect of script strategy and reflective practice on nursing students' reasoning development.","authors":"Fatemeh Bahramnezhad, Fatemeh Keshmiri","doi":"10.1186/s13104-025-07338-5","DOIUrl":"10.1186/s13104-025-07338-5","url":null,"abstract":"Objective: The script strategy is a multistage, adaptive method designed for integration with established clinical reasoning frameworks to enhance educational outcomes for clinical students. This study evaluated the effect of these pedagogical interventions on nursing students' learning, satisfaction levels, and learning experience. This quasi-experimental study was conducted at Tehran University of Medical Science, involving nursing students enrolled in the clerkship course (n = 58). The intervention group was trained using the script strategy method combined with structured reflection within a workplace-based education setting. A hypothesis formation test and a 10-item questionnaire were used to evaluate the students' clinical reasoning skills. In addition, the experiences of the nursing students were explored through conventional content analysis.Results: The students' scores in reasoning skills were 18.54 ± 11.33 (out of 20), which was significantly above the cutoff value of 10.8. The students' satisfaction score was 74.37 ± 16.31 on a 100-point scale. The students' experiences were explored under the theme \"a learner as a director in the learning process.\" The integration of script strategy enhances the reasoning abilities of nursing students. This approach fosters a sense of responsibility for their learning and cultivates critical thinking skills essential for professional nurses in dynamic healthcare environments.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"271"},"PeriodicalIF":1.6,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12224862/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144552365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antimicrobial susceptibility pattern of Staphylococcus Aureus isolated from clinical specimens at University of Gondar comprehensive specialized referral hospital northwest Ethiopia; a retrospective study. 埃塞俄比亚西北部贡达尔大学综合专科转诊医院临床标本分离金黄色葡萄球菌的药敏模式回顾性研究。

IF 1.6

BMC Research Notes Pub Date : 2025-07-01 DOI: 10.1186/s13104-025-07335-8

Debaka Belete, Tinsae Gashaw, Solomon Belay, Aklilu Ambachew

{"title":"Antimicrobial susceptibility pattern of Staphylococcus Aureus isolated from clinical specimens at University of Gondar comprehensive specialized referral hospital northwest Ethiopia; a retrospective study.","authors":"Debaka Belete, Tinsae Gashaw, Solomon Belay, Aklilu Ambachew","doi":"10.1186/s13104-025-07335-8","DOIUrl":"10.1186/s13104-025-07335-8","url":null,"abstract":"Objective: Emergence of antimicrobial resistance is a major public health problem worldwide, particularly in developing countries. The aim of this study was to determine the antimicrobial resistance pattern of Staphylococcus aureus isolate from different clinical specimens at University of Gondar comprehensive specialized hospital. This retrospective study used laboratory records of 25870 clinical specimens submitted for bacterial culture submitted to the microbiology laboratory of University of Gondar comprehensive specialized hospital for bacterial culture and sensitivity testing from July 2018 and June 2022. Records from specimens positive for Staphylococcus aureus isolates were included for analysis.Result: Of the total 25,870 samples culture records, 4653 (18%) were culture positive for bacteria. A total of 1057 S. aureus isolates were collected from clinical specimens such as: wound discharge (342; 32.4%), blood (312; 29.5%), cerebrospinal fluid (16; 1.5%), urine (21; 2%), other body fluids (71; 6.7%) and other discharge like ear discharge, eye discharge and vaginal discharge295; 28%). The prevalence of methicillin resistant S. aureus was 33.8% (233/698) and the overall prevalence of multi-drug resistant S. aureus out of 1057 S. aureus isolates was 36% (380/1057).","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"268"},"PeriodicalIF":1.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12220124/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144538909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Novel haplotypes of genetic polymorphisms in alcohol metabolizing enzymes in Kampala, Uganda. 乌干达坎帕拉地区酒精代谢酶遗传多态性的新单倍型

IF 1.6

BMC Research Notes Pub Date : 2025-07-01 DOI: 10.1186/s13104-025-07331-y

Rodney Okwasiimire, Rhona K Baingana, Dennis M Kasozi

{"title":"Novel haplotypes of genetic polymorphisms in alcohol metabolizing enzymes in Kampala, Uganda.","authors":"Rodney Okwasiimire, Rhona K Baingana, Dennis M Kasozi","doi":"10.1186/s13104-025-07331-y","DOIUrl":"10.1186/s13104-025-07331-y","url":null,"abstract":"Objective: Alcohol is metabolized to acetaldehyde by alcohol dehydrogenases (ADH) and subsequently to acetate by aldehyde dehydrogenases (ALDH). Single nucleotide polymorphisms (SNPs) in ADH1B, ADH1C and ALDH2 genes lead to haplotypes encoding isozymes which influence development of alcoholism. The distribution of these haplotypes in Uganda has not been documented. The aim of this study was to determine genotype, allele, and haplotype frequencies of SNPs in ADH1B, ADH1C, and ALDH2 genes in Uganda.Results: Five SNPs: ADH1B (rs1229984 and rs2066702), ADH1C (rs1693482 and rs698) and ALDH2 (rs671) were analyzed by PCR-restriction fragment length polymorphism assays in 250 samples. The frequencies of the fast-metabolizing alleles ADH1C*1, ADH1B*3, and ADH1B*2 were 49.6%, 18.2% and 0.2% respectively. The nonprotective allele ADH1B*1 had a high frequency of 81.6% and ADH1C*2 was 10.6%. A novel allele ADH1C*new (Arg271Val349) comprising G at ADH1C rs1693482and G at ADH1C rs698 was identified with a frequency of 39.8%. Of the seven ADH1B-ADH1C haplotype combinations identified, ADH1B*1-ADH1C*1 was the most prevalent (48.4%). Notably ADH1B*1-ADH1C* new, had the second highest frequency (25.2%). Our study provides the first data on novelADH1B-ADH1C haplotypes in alcohol metabolizing genes in the Ugandan population.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"249"},"PeriodicalIF":1.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12211130/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144538984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Protective antibodies against diphtheria, tetanus, and pertussis following revaccination in children and young adults having undergone haematopoietic stem cell transplantation. 在接受造血干细胞移植的儿童和年轻人中，再次接种疫苗后可产生白喉、破伤风和百日咳的保护性抗体。

IF 1.6

BMC Research Notes Pub Date : 2025-07-01 DOI: 10.1186/s13104-025-07332-x

Ravipreeya Sukswadi Na Ayudhya, Chanya Pongpatipat, Usanarat Anurathapan, Samart Pakakasama, Suradej Hongeng, Chompunuch Klinmalai, Nopporn Apiwattanakul

{"title":"Protective antibodies against diphtheria, tetanus, and pertussis following revaccination in children and young adults having undergone haematopoietic stem cell transplantation.","authors":"Ravipreeya Sukswadi Na Ayudhya, Chanya Pongpatipat, Usanarat Anurathapan, Samart Pakakasama, Suradej Hongeng, Chompunuch Klinmalai, Nopporn Apiwattanakul","doi":"10.1186/s13104-025-07332-x","DOIUrl":"10.1186/s13104-025-07332-x","url":null,"abstract":"Objective: Haematopoietic stem cell transplantation (HSCT) eliminates pre-existing immunity, necessitating revaccination. This study aimed to assess the prevalence of protective antibody titres against diphtheria, pertussis, and tetanus in pediatric and young adult HSCT recipients at least four years post-revaccination.Results: A cross-sectional study was conducted in 94 post-HSCT patients (aged 5-25 years) who completed a three-dose DTP series at least four years prior. Protective anti-tetanus and anti-diphtheria antibody titres were detected in 93.6% and 81.9% of participants, respectively, at least four years post-revaccination. However, only 9.4% had protective anti-pertussis titres, which remained low within five years of revaccination. Factors associated with protective anti-tetanus included higher absolute lymphocyte counts (ALC) 1-year post-revaccination, while corticosteroid use during revaccination was negatively associated. ALC at the 3rd dose of vaccination was associated with a protective anti-diphtheria titre. A booster dose of Tdap resulted in seroconversion in 80.0% for diphtheria, 47.4% for pertussis, and 100% for tetanus. These findings support an earlier booster dose of DTP vaccination in post-HSCT patients.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"251"},"PeriodicalIF":1.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12210706/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144538987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Protective mechanism of polysaccharides from Phellinus linteus on H9c2 cardiomyocyte injury induced by hypoxia/reoxygenation. 茶树多糖对缺氧/复氧诱导H9c2心肌细胞损伤的保护机制

IF 1.6

BMC Research Notes Pub Date : 2025-07-01 DOI: 10.1186/s13104-025-07308-x

Xiaoyu Ren, Qingxian Mei, Yuan Zhou, Lili Jiang, Fei Liu, Jinfeng Wang

{"title":"Protective mechanism of polysaccharides from Phellinus linteus on H9c2 cardiomyocyte injury induced by hypoxia/reoxygenation.","authors":"Xiaoyu Ren, Qingxian Mei, Yuan Zhou, Lili Jiang, Fei Liu, Jinfeng Wang","doi":"10.1186/s13104-025-07308-x","DOIUrl":"10.1186/s13104-025-07308-x","url":null,"abstract":"Objective: This study aimed to explore the protective mechanism of Phellinus linteus polysaccharides (Phps) against hypoxia/reoxygenation (H/R)-induced injury in H9c2 cardiomyocytes, focusing on oxidative stress, apoptosis, and PI3K-AKT pathway regulation.Results: H9c2 cardiomyocytes were divided into control, H/R model, and Phps-treated groups (low/medium/high doses). The H/R model (established by exposing cells to hypoxia for 10 h followed by 4 h of reoxygenation.) induced significant injury: cell viability decreased, SOD activity reduced by 45%, and Bcl-2 expression declined at both mRNA and protein levels, while LDH activity increased by 66%, MDA content surged by 99%, and Bax expression (mRNA/protein) and p-PI3K and p-AKT levels were upregulated, with statistical significance (P < 0.05 vs. control). Compared to the H/R model group, the Phps treatment (low, medium, high) groups showed a significant increase in H9c2 cardiomyocytes viability, SOD activity, and mRNA and protein expression levels of Bcl-2. The LDH activity, MDA content, mRNA levels of Bax, and protein expression levels of Bax, p-PI3K and p-AKT significantly decreased, with statistical significance (P < 0.05). These results suggest that Phps may improve H/R induced damage in H9c2 cardiomyocytes by downregulating the ratio of Bax/Bcl-2 through the PI3K-AKT pathway.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"263"},"PeriodicalIF":1.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12220461/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144538988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A data set for mental and physical stress, loneliness, and life satisfaction before and during the COVID-19 pandemic and the role of working from home. 关于COVID-19大流行之前和期间的精神和身体压力、孤独感和生活满意度以及在家工作的作用的数据集。

IF 1.6

BMC Research Notes Pub Date : 2025-07-01 DOI: 10.1186/s13104-025-07329-6

Franziska Emmerich, Julia Junghans, Markus Zenger, Elmar Brähler, Yve Stöbel-Richter, Lisa Irmscher, Ernst Peter Richter, Hendrik Berth

引用次数: 0

Effect of carotid artery stenosis on collateral flow status in patients with acute ischemic stroke after mechanical thrombectomy. 颈动脉狭窄对急性缺血性脑卒中机械取栓后侧支血流状态的影响。

IF 1.6

BMC Research Notes Pub Date : 2025-07-01 DOI: 10.1186/s13104-025-07320-1

Jing-Liang Su, De-You Xue, Xiang-Yang Wei, Xin-Yu Yang

{"title":"Effect of carotid artery stenosis on collateral flow status in patients with acute ischemic stroke after mechanical thrombectomy.","authors":"Jing-Liang Su, De-You Xue, Xiang-Yang Wei, Xin-Yu Yang","doi":"10.1186/s13104-025-07320-1","DOIUrl":"10.1186/s13104-025-07320-1","url":null,"abstract":"Objective: Collateral circulation is critical for mitigating ischemic damage in acute ischemic stroke (AIS). This dual-center retrospective cohort study enrolled 240 patients with AIS undergoing mechanical thrombectomy (MT) aimed to evaluate how carotid artery stenosis severity affects collateral flow dynamics, functional outcomes, and 90-day survival.Results: Patients divided into mild stenosis group (n = 69), moderate stenosis group (n = 117) and severe stenosis and occlusion group (n = 54). Following MT, the ASITN/SIR and BATMAN scores showed a significant increase across all groups compared to pre-MT levels (P < 0.05). However, a notable pattern emerged where both the pre-MT and post-MT scores in the severe stenosis and occlusion group were inferior to those observed in the moderate stenosis group and mild stenosis group (P < 0.05). Multivariate logistic regression showed that patients with severe stenosis and occlusion (OR = 3.09, 95% CI:2.56-3.73, p < 0.001), moderate stenosis (OR = 1.42, 95% CI: 1.13-1.78, p = 0.002), hypertension (OR = 3.36, 95% CI:1.47-7.63, p = 0.003) and T2DM (OR = 4.58, 95% CI:1.52-13.78, p = 0.006) were independent risk factors for poor collateral circulation. Kaplan-Meier curve analysis showed that the 90-day survival rate in the severe stenosis and occlusion group was lower than other groups (χ2 = 26.716, P < 0.001). These findings highlight the importance of preoperative stenosis evaluation to guide therapeutic strategies.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"253"},"PeriodicalIF":1.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12211949/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144538979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0