BMC Research Notes最新文献

{"title":"Effectiveness of a ultraviolet (UV)-equipped waste box in reducing bacterial contamination in laboratory waste.","authors":"Slamet Wardoyo, Deddy Adam, Taufik Anwar, Jessica Juan Pramudiatia","doi":"10.1186/s13104-025-07375-0","DOIUrl":"10.1186/s13104-025-07375-0","url":null,"abstract":"<p><strong>Introduction: </strong>Infectious waste handling is a serious problem in healthcare, especially laboratory units. With the increase in research activities, innovative designs are needed that can reduce the risk of contamination and effective solutions are needed for laboratory waste management. Management of infectious solid waste often involves expensive techniques such as incineration, chemical treatment or autoclaving to minimize hazardous substances. Waste left over from laboratory testing activities requires special treatment before disposal. This study aims to test the ability of the waste box equipped with Ultraviolet (UV) in inhibiting the growth of Staphyloccus aereus.</p><p><strong>Methods: </strong>This study used a simple 2 mm thick acrylic bin model with a Black box height of 50 cm and a base of 1600 cm², equipped with Ultra Violet (UV) C (wavelength 200-280) to inactivate some viruses and bacteria. The bacteria used was Staphylococcus aureus which was characterized through Gram staining, morphology, and biochemical tests.</p><p><strong>Results: </strong>The study demonstrated the effectiveness of using ultraviolet lamps in the waste box to reduce the growth of staphylococcus aureus bacteria, which is an indicator of infectious waste bacteria.</p><p><strong>Conclusion: </strong>In conclusion, the use of mini-bin bins with UV lamps can be an effective alternative in handling infectious waste in testing laboratories, but further testing is needed for the recovery of other bacteria, viruses, and fungi.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"416"},"PeriodicalIF":1.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12486523/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Continuous passive motion for prevention of ankle contracture and muscle loss in mechanically ventilated ICU patients.","authors":"Chen-Chun Lin, Yi-Jia Lin, Hsien-Chun Wang, Wei-Chun Hsu","doi":"10.1186/s13104-025-07457-z","DOIUrl":"10.1186/s13104-025-07457-z","url":null,"abstract":"<p><strong>Objective: </strong>This prospective, within-patient controlled study aimed to evaluate the effects of continuous passive motion therapy on ankle mobility and muscle morphology in mechanically ventilated ICU patients-a population vulnerable to ICU-acquired weakness and joint contractures.</p><p><strong>Results: </strong>Twelve ventilated patients completed the protocol. The ankle treated with continuous passive motion therapy showed a significant improvement in dorsiflexion passive range of motion, increasing from 9.90° [IQR: 6.20-13.15°] to 12.99° [IQR: 9.07-20.20°] (p = 0.004), while the control ankle showed no significant change (p = 0.388). The increase in passive range of motion was significantly greater in the continuous passive motion treated ankle compared with the control (4.18° vs. 0.42°, p = 0.028). No significant between-limb differences were observed in tibialis anterior muscle thickness, cross-sectional area, or pennation angle. Echointensity increased in both limbs without group differences. These findings suggest that continuous passive motion can be applied as an early intervention to preserve ankle mobility in ICU patients. Although short-term muscle morphology changes were not significant, passive range of motion gains suggest continuous passive motion may help prevent contractures and support early rehabilitation during critical illness.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov NCT06944431, registered on April 25, 2025. Retrospectively registered.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"409"},"PeriodicalIF":1.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12486782/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reproductive autonomy of visually impaired women: a cross-sectional study in Coimbatore and Tiruchirappalli districts, Tamil Nadu.","authors":"Sampath Kumar Srinivasan, Pitchaimani Govindharaj, Prabu Gopal","doi":"10.1186/s13104-025-07496-6","DOIUrl":"10.1186/s13104-025-07496-6","url":null,"abstract":"<p><strong>Objectives: </strong>Reproductive autonomy is a fundamental human right, yet it remains a complex issue for visually impaired women. Therefore, this study aims to explore reproductive autonomy and examine the factors associated with reproductive autonomy among visually impaired women.</p><p><strong>Results: </strong>A cross-sectional study was carried out in Tamil Nadu, India, involving 333 visually impaired women aged 18-44 (36.09 ± 5.97) from two districts. The study used a Reproductive Autonomy Scale (RAS) to assess reproductive autonomy, which comprises decision-making, freedom from coercion, and communication domains. The respondents had mean scores of 2.13 for decision-making, 2.05 for coercion, 3.74 for communication. The study found no significant differences in age, education, occupation, house ownership, community, and religion. Significant differences were found in the number of children across all domains, and the total RAS scores indicated that women with two or more children had higher reproductive autonomy. In spouse's disability, spouses with disabilities scored higher in decision-making domain compared to spouses without disabilities. The study concluded that the visually impaired women had a higher degree of reproductive autonomy. The results highlight that most women experience shared reproductive decision-making and supportive communication with their partners, with minimal instances of coercion.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"413"},"PeriodicalIF":1.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12487622/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of the relationship between daily alcohol intake and serum 25(OH) vitamin D concentrations in a sample of healthy young Cameroonian men.","authors":"Jan René Nkeck, Daniela Tinking Tchotsoua, Rosine Eliscar Yassang Noubet, Doris Bibi Essama, Baudelaire Fojo, Wulfran Nganou Tetsoguim, Wilson Chia Tamko, Falmata Amazia, Vicky Jocelyne Ama Moor, Madeleine Ngandeu-Singwé","doi":"10.1186/s13104-025-07466-y","DOIUrl":"10.1186/s13104-025-07466-y","url":null,"abstract":"<p><strong>Introduction: </strong>The association between alcohol consumption and vitamin D status in young men remains controversial. Few data are available from sub-Saharan Africa, although necessary for better prevention of metabolic bone disease in adulthood. This study aimed to analyze the relationship between regular alcohol consumption and vitamin D status in young Cameroonian men.</p><p><strong>Methods: </strong>It was a cross-sectional study on healthy males aged 18 to 45 with regular alcohol consumption within the last three months. We assessed their ethylic index (EI), hematological and hepatic biomarkers of chronic alcohol consumption, and 25 (OH) vitamin D (25(OH)D) concentrations, which were compared according to alcohol consumption (low < 20, moderate 20-39.9 and elevated ≥ 40 g/day) using ANOVA.</p><p><strong>Results: </strong>155 participants were included, with a mean age of 31 (SD 6) years, a median alcohol consumption duration of 10 [7; 15] years and a median EI of 24 [14; 27] g/day. They mostly consumed beer (95%), with low (42%) and elevated (23%) predominant consumptions. Vitamin D deficiency (< 20ng/mL) was found in 63%. There was no difference in mean 25(OH)D concentrations between the three alcohol consumption groups. No correlation was found between the biomarkers of chronic alcohol consumption studied and 25(OH)D concentrations.</p><p><strong>Conclusions: </strong>There appears to be no relationship between 25(OH)D concentrations and daily alcohol consumption in young Cameroonian men. Nevertheless, more data are needed, including vitamin D metabolism parameters to better understand this relationship.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"415"},"PeriodicalIF":1.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12487613/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neutrophil extracellular traps as a predictive biomarker for severe Mycoplasma pneumonia in children: a clinical observational study.","authors":"Xiaoping Fan, Junsheng Jiang","doi":"10.1186/s13104-025-07334-9","DOIUrl":"10.1186/s13104-025-07334-9","url":null,"abstract":"","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"394"},"PeriodicalIF":1.7,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12486646/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145198362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gingival depigmentation by conservative injectable vitamin C in comparison with scalpel surgery: a randomized controlled split-mouth clinical trial.","authors":"Manal M Al-Hajri, Abdulaziz M Tawfik, Redhwan Saleh Al-Gabri, Sadam Ahmed Elayah, Ahmed Yaseen Alqutaibi","doi":"10.1186/s13104-025-07476-w","DOIUrl":"10.1186/s13104-025-07476-w","url":null,"abstract":"<p><strong>Background: </strong>Gingival pigmentation (GP) is a common aesthetic concern in dentistry. While GP is not harmful, it can cause psychological distress. This study aimed to evaluate the efficacy of vitamin C injection for managing GP compared to the standard scalpel surgery.</p><p><strong>Methods: </strong>The study involved 20 healthy patients aged 19-36. A randomized split-mouth design was used, with vitamin C injections (group 1) on one side and scalpel surgery (group 2) on the other side of the maxilla. Clinical evaluations of gingival depigmentation were conducted preoperatively and at first, second, three weeks and six months postoperatively, using the Gingival Pigmentation Index (GPI), Melanin Pigmentation Index (MPI), Dummett Oral Pigmentation Index (DOPI) and Color Intensity Analysis using ImageJ. Pain and patient satisfaction were measured with a visual analogue scale (VAS) after treatment.</p><p><strong>Results: </strong>The GPI, MPI, and DOPI showed no significant differences in pigmentation between the groups at baseline and after six months (P = 1.0 and 0.80 for GPI; P = 1.00 and 0.54 for MPI; P = 1.00 and 0.59 for DOPI). However, after three weeks, greater depigmentation was noted on the surgical side. The vitamin C group reported lower pain and itching levels (itch: P = 0.02; pain: P = 0.00).</p><p><strong>Trial registration: </strong>This randomized controlled trial was retrospectively registered in the Thai Clinical Trial Registry at 05-7-2024 ( www.thaiclinicaltrials.org ), and its registration number is TCTR20240715003.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"408"},"PeriodicalIF":1.7,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12487293/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145198098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sodium alginate-hyaluronic acid composite particles for doxorubicin delivery: in vitro characterization and cytotoxicity evaluation.","authors":"Zhiyu She, Fangxia Zhang, Duanfei Li, Yong Ji","doi":"10.1186/s13104-025-07411-z","DOIUrl":"10.1186/s13104-025-07411-z","url":null,"abstract":"","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"392"},"PeriodicalIF":1.7,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12486956/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145198421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors associated with delayed neonatal bathing in Afghanistan: insights from the 2022-2023 multiple indicator cluster survey.","authors":"Muhammad Haroon Stanikzai, Essa Tawfiq, Massoma Jafari, Zainab Ezadi, Abdul Wahed Wasiq, Omid Dadras","doi":"10.1186/s13104-025-07495-7","DOIUrl":"10.1186/s13104-025-07495-7","url":null,"abstract":"<p><strong>Objectives: </strong>Delayed neonatal bathing, defined as postponing the first bath until at least 24 h after birth, is a key component of essential newborn care that helps maintain thermal stability and reduces the risk of hypothermia and infection. This study estimates the national prevalence of delayed neonatal bathing and identifies its determinants in Afghanistan. This study analyzed data from the Afghanistan Multiple Indicator Cluster Survey (MICS) 2022-2023. We fitted multivariable binary logistic regression models to determine factors associated with delayed neonatal bathing.</p><p><strong>Results: </strong>Out of 7,702 women, 68.6% reported delayed neonatal bathing. After adjustment, the odds of delayed bathing were higher among women whose household head completed primary education (AOR 1.38; 95% CI: 1.10-1.73), those delivering in health facilities (AOR 1.57; 95% CI: 1.29-1.91), and women attending 1-3 antenatal care (ANC) visits (AOR 1.29; 95% CI: 1.08-1.53) or 4-7 ANC visits (AOR 1.40; 95%CI: 1.14-1.72) or ≥ 8 ANC visits (AOR 2.05; 95% CI: 1.46-2.87). Conversely, women in the richest wealth quintile were less likely to delay bathing (AOR 0.69; 95% CI: 0.51-0.94). Tailored interventions that leverage antenatal contacts and facility-based care may further improve the adoption of optimal newborn bathing practices in Afghanistan.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"401"},"PeriodicalIF":1.7,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12487455/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145198107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HIV prevalence in pregnant women attending antenatal consultations in Senegal in 2021.","authors":"Abou Abdallah Malick Diouara, Sarbanding Sané, Sophie Deli Tene, Seynabou Coundoul, Fatou Thiam, Habibou Sarr, Halimatou Diop Ndiaye, Ousseynou Ndiaye, Seynabou Lo, Fodé Danfakha, Marie Edouard Faye Diéme, Babacar Biaye, Noel Magloire Manga, Cheikh Momar Nguer, Coumba Toure Kane, Martine Peeters, Ahidjo Ayouba","doi":"10.1186/s13104-025-07491-x","DOIUrl":"10.1186/s13104-025-07491-x","url":null,"abstract":"<p><p>HIV/AIDS infection is a significant public health issue, particularly among vulnerable populations like pregnant women. Despite progress in prevention, diagnosis, early management and treatment, there is still a need to strengthen efforts toward eliminating mother-to-child transmission (eMTCT). This study aimed to update the seroprevalence of HIV in pregnant women attending antenatal consultations in Senegal. Blood samples from 1,227 participants were collected from March to July 2021. The plasma samples were processed within 2 h after collection and were frozen at - 80 °C or stored at - 20 °C on site until processing. Serological tests were carried out using national diagnostic algorithms. Rapid diagnostic tests (RDTs) were used at all screening stages, starting with the DetermineTM HIV-1/2 Abott test. Positive samples were confirmed with the SD bioline HIV-1/2 3.0 test and Multisure^® MP diagnostics typing test, following the manufacturer's instructions. Statistical tests were conducted using JMP^® Pro Version 15.0.0 software. The HIV prevalence found was 1.05% [95% CI: 0.69-1.80], with variations by locality: Kédougou at 2.2% [95% CI: 1.20-4.25] and Ziguinchor at 1.5% [95% CI: 0.59-3.83]. No HIV cases were found in Dakar and Saint-Louis. Considering the national HIV prevalence and the risk of mother-to-child transmission, these results remain concerning for Senegal and stress the need to continued awareness-raising and targeted interventions in the South and South-East regions are necessary.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"399"},"PeriodicalIF":1.7,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12487344/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145198118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of HIV disclosure and related predictors on CD4 cell count among adults under first-line ART regimen at Felege Hiwot comprehensive specialized referral hospital, North West Ethiopia.","authors":"Abdela Assefa Bekele, Awoke Seyoum Tegegne, Nurye Seid Muhie","doi":"10.1186/s13104-025-07477-9","DOIUrl":"10.1186/s13104-025-07477-9","url":null,"abstract":"<p><strong>Background: </strong>Disclosure of HIV status potentially leads patients aware of their infection and accelerates access to timely care. The main objective of the current study was to investigate the impact of disclosure and related predictors on CD4 cell count among HIV positive adults under first-line ART Regimen at Felege Hiwot Comprehensive specialized Hospital, North West Ethiopia.</p><p><strong>Methods: </strong>A hospital based retrospective study design was conducted to investigate the impact of disclosure and related predictors on CD4 cell count. Independent samples t-test was conducted to compare the magnitude of CD4 cell count between adults disclosed and those who did not. A negative Binomial regression model was conducted to investigate the predictors of CD4 cell count.</p><p><strong>Result: </strong>Out of 300 adult participants, about 76% of the patients disclosed their disease status to their family members. The correlation for CD4 cell count and disclosure of disease status was about 0.4607 which indicates that disclosure had a positive impact on the progress of CD4 cell count for HIV-adults under treatment. The current study indicates that among the predictor variables, age of patients (β= -0.0744, p-value = 0.0017), Visiting time (β = 0.005296, p-value = 0.0017), baseline CD4 cell count (β = 0.00526, p-value < 0.0001), disclosure of HIV disease (β = 0.5084, p-value < 0.0001), non-educated patients (β = -0.3720, p-value < 0.00009), employed patients (β = 0.2062, p-value < 0.0001), adherent patients (β = 0.1339, p-value < 0.0001), WHO stage I (β = 0.5712; p-value < 0.0001), TB infected HIV positive adult (β= -0.2035, p-value < 0.0008), HIV positive adults without opportunistic infection (β = 0.3001, p-value < 0.0001), Social support (β=- 0.1981, p-value < 0.0004) had significant effect for the variation of CD4 cell count.</p><p><strong>Conclusion: </strong>The result of this study concluded that, disclosure of HIV disease status had positive significant impact for CD4 cell count among the patients under treatment at first line regimen. Especial attention should be given for HIV positive adults with TB and other opportunistic infection and for aged HIV patients. In addition, health staff should conduct health related education for individuals regard to use of medication adherence and use of disclosing HIV status for treatment outcomes.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"403"},"PeriodicalIF":1.7,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12486694/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145198181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}