BMC Research Notes最新文献

{"title":"A diffusion-conditioned representation learning framework for disease classification in medical imaging.","authors":"Jutika Borah, Rajkumar Saini, Abdur R Fayjie, Debarun Chakraborty, Hidam Kumarjit Singh","doi":"10.1186/s13104-026-07858-8","DOIUrl":"10.1186/s13104-026-07858-8","url":null,"abstract":"<p><strong>Objective: </strong>Recently, deep learning models in medical imaging have undergone tremendous advancements. However, these deterministic discriminative models often tend to overfit and produce overconfident predictions. To explore a more efficient strategy, we propose a diffusion-conditioned representation learning that leverages the internal dynamics of a diffusion model to extract noise-level awareness and diverse semantic representations in disease classification and detecting distributional shifts. The proposed method inherently encodes aleatoric uncertainty by sampling features from multiple denoising time steps, which is then used to regularize prediction during training via entropy regularized loss.</p><p><strong>Result: </strong>We conducted extensive experimentation over five diverse clinical datasets, and our framework demonstrates competitive performance with reduced prediction entropy and improved robustness to input degradation. The negative entropy-accuracy correlation, expected calibration error, and dynamic uncertainty demonstrate the effectiveness of the proposed framework in classification tasks. Our framework achieved competitive performance compared with traditional convolutional neural networks and vision transformers with an AUC of 83.81%, 97.45%, 86.15% and 96.75% on datasets 1, 2, 3 and 4, respectively. The reduced ECE values on the datasets demonstrate the calibrated performance of the proposed method.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13663269/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148520010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation analysis of arterial blood lactate levels with major in-hospital adverse cardiovascular events after coronary intervention in patients with acute myocardial infarction.","authors":"Zhang Juan, Ma Chunhua, Gu Lijiang Yikeran, Wang Fei, Wang Yong, Sheng Shanshan, Wang Dong","doi":"10.1186/s13104-026-07628-6","DOIUrl":"10.1186/s13104-026-07628-6","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the relationship between percutaneous coronary intervention (PCI) and major in-hospital adverse cardiovascular events (MACEs) in patients with acute myocardial infarction (PCI) after PCI by monitoring the level of arterial lactate at the time of admission.</p><p><strong>Methods: </strong>A total of 77 patients with acute myocardial infarction who received emergency PCI treatment in our hospital from June 2022 to December 2023 were enrolled, and they were divided according to the preoperative arterial blood lactate level after admission, the control group (40 cases) with normal lactate and the observation group (37 cases) with elevated lactate were enrolled. At the same time, the following major cardiovascular adverse events in the hospital were recorded during the course of the disease: cardiogenic death, cardiogenic shock, new-onset heart failure, angina/exacerbation of pre-existing heart failure, and malignant arrhythmia.</p><p><strong>Results: </strong>The incidence of major cardiovascular adverse events in the observation group was higher than that in the control group, and the difference was statistically significant(P < 0.05). Compared with the control group, the observation group had a higher peak cTnI (P < 0.05), a faster heart rate (P < 0.05), a lower systolic blood pressure (P < 0.05), a higher fasting blood glucose (P < 0.05), and a longer time from symptom to catheter (P < 0.05). With the increase of lactate level, the incidence of major cardiovascular adverse events in the hospital showed an overall upward trend. Binary logistic regression analysis showed that heart rate, systolic blood pressure, elevated lactate and fasting blood glucose were the main factors associated with in-hospital adverse cardiovascular events in patients with acute myocardial infarction after PCI.</p><p><strong>Conclusions: </strong>The level of lactate in the arterial blood can be used as an effective early warning indicator to evaluate the occurrence of major adverse cardiovascular events in the hospital.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13651223/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148454701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Survey dataset of self-reported gaming preferences, Bartle test responses, and immersive tendencies among 175 IT students and teachers.","authors":"Ján Skalka, Matúš Valko","doi":"10.1186/s13104-026-07948-7","DOIUrl":"10.1186/s13104-026-07948-7","url":null,"abstract":"<p><strong>Objectives: </strong>Motivational orientation and immersive tendency describe complementary questionnaire-based dimensions of player characterization. Motivation instruments capture why players report engaging with games, whereas immersive-tendency instruments describe individual predispositions toward absorption, involvement, and attention focusing in mediated environments. To support reuse in questionnaire-based player modelling, we created an open, item-level, single-cohort survey dataset linking Bartle Test responses, ITQ-18 responses, demographics, and self-reported gaming preferences among IT students and teachers.</p><p><strong>Data description: </strong>The dataset contains a single comma-separated values (CSV) file (one record per participant), with n = 175 and 64 variables. It includes: demographics (age, gender); self-reported weekly gaming time (total and excluding mobile); preferred mode (single-player or multiplayer); binary genre indicators with the most popular genre; item-level responses from the 30-item Bartle Test of Gamer Psychology with response options Achiever, Socializer, Explorer, Killer; and 18 items from the Immersive Tendencies Questionnaire rated on a seven-point Likert scale. The dataset is fully anonymized, contains no free-text fields, and uses categorical codes to facilitate reuse.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13656512/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148469119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Not all older adults are viewed alike: feeling thermometer ratings toward older-adult subgroups in Japan.","authors":"Yuho Shimizu","doi":"10.1186/s13104-026-07949-6","DOIUrl":"10.1186/s13104-026-07949-6","url":null,"abstract":"<p><strong>Objective: </strong>This study examined whether feeling thermometer ratings toward older adults vary across older-adult subgroups and how such ratings are positioned relative to other common prejudice targets. Using an online sample of 520 Japanese adults aged 18-64, we assessed feeling thermometer ratings (0 = coldest, 100 = warmest) for 14 targets: nursing-home, on-deathbed, handicapped, solitary, senile, on-welfare, and grumpy older adults, as well as immigrants and refugees, foreign tourists, sexual minorities, racial minorities, and persons with mental, physical, or intellectual disabilities. We also tested whether these evaluations differed by participants' age group (younger and middle-aged adults).</p><p><strong>Results: </strong>Feeling thermometer ratings differed significantly across targets, indicating that older adults were not evaluated as a homogeneous category. Relatively lower ratings were observed for some subgroups, particularly on-welfare and grumpy older adults, suggesting that evaluations of older adults may vary depending on the specific attributes associated with the target. Ratings also differed by participant age group: middle-aged adults tended to report warmer evaluations than younger adults across most of the targets, including all older-adult subgroups, although these differences should be interpreted cautiously given the small interaction effect.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13656563/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148469075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Circulation of arctic canine distemper virus in diarrheic dogs in Iran: molecular detection and phylogenetic characterization.","authors":"Hamid Staji, Sara Kashi, Iradj Ashrafi Tamai, Seyedeh Fatemeh Angoshtan, Atrin Behmanesh","doi":"10.1186/s13104-026-07947-8","DOIUrl":"10.1186/s13104-026-07947-8","url":null,"abstract":"<p><p>Canine distemper virus (CDV) is a pathogen that causes systemic infection in dogs and wildlife. Among the highly variable regions in the genome of the virus, the H gene is commonly sequenced for phylogenetic studies. The aim of the present study was to screen for the presence of CDV infection in dogs in Iran and to identify the genotype of the virus. Seventy-five dogs with gastrointestinal symptoms were screened via an immunochromatographic test. Fifty of them were positive. CDV was isolated from rectal swabs, and PCR was performed. The top 10 positive cases were subsequently selected for sequencing. Phylogenetic analyses were subsequently conducted. Among the 75 dogs analyzed, 50 (66.7%) dogs were found to be infected with CDV via rapid tests. All 10 sequenced isolates were from the Arctic lineage, forming a monophyletic cluster. Our sequences closely clustered with some European strains. Some nucleotide variations were observed. The present study reports the presence of Arctic-like CDV strains in diarrheic dogs in Tehran. Ongoing molecular surveillance will help in assessing any alterations in genetic diversity and vaccine efficacy. Future studies in other regions in Iran would be helpful.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13656588/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148469099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Color Doppler ultrasound study: assessing orbital hemodynamics and vascular changes in mucosal lichen planus.","authors":"Abbas Mohammadi, Nader Pazyar, Mohamad Ghasem Hanafi, Samaneh Azhineh","doi":"10.1186/s13104-026-07942-z","DOIUrl":"10.1186/s13104-026-07942-z","url":null,"abstract":"<p><strong>Objective: </strong>Lichen planus (LP) is a chronic inflammatory condition that can have systemic implications, including effects on vascular health. This exploratory study aimed to evaluate orbital hemodynamics and vascular changes in patients with mucosal LP using color Doppler ultrasound (CDU).</p><p><strong>Results: </strong>This retrospective case‑control study enrolled 25 mucosal LP patients along with 30 age‑ and gender‑matched subjects. CDU was used to evaluate the resistive index (RI), pulsatility index (PI), peak systolic velocity (PSV), and end‑diastolic velocity (EDV) in the ophthalmic artery (OA), short posterior ciliary arteries (PCAs), and central retinal artery (CRA). The severity of mucosal LP was assessed with the White Erosive Atrophic Modified Scoring System (WEA‑MOD). All patients underwent complete ophthalmic examination as well as determination of choroidal thickness (CT) using a high‑speed, high‑resolution spectral‑domain optical coherence tomography (SD‑OCT) device. Doppler ultrasonographic measurements revealed significant differences in multiple hemodynamic parameters between LP patients and controls associated with the PCA (p < 0.05). Notable differences were observed in parameters such as OA‑RI, OA‑PI, CRA‑EDV, CRA‑RI, CRA‑PI, and PCA‑PSV (all p < 0.05), with significant variations correlating with different LP severity scores (p = 0.021). Although CT measurements did not differ significantly between the two groups overall, notable variations were observed when assessing CT across different levels of LP severity. CT measurements were significantly lower in the LP group, and significant variations were observed when assessing CT across different levels of LP severity (p < 0.001). These associational findings suggest that mucosal LP severity is associated with altered orbital hemodynamics. These findings raise the possibility that color Doppler ultrasound might serve as a non‑invasive tool to identify patients at higher risk of subclinical ocular vascular changes. Prospective studies are needed to determine whether these hemodynamic alterations predict future ocular complications and whether they warrant monitoring or adjunctive vascular‑protective strategies. Due to the retrospective and cross‑sectional design, causality cannot be inferred. This hypothesis‑generating study underscores the need for larger, longitudinal investigations.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13644267/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148435010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Facilitating access to clinical data from a randomized controlled trial of complex adaptive design.","authors":"Victor Olago, Victoria Yorke-Edwards, Louise C Brown, Matt Sydes, Tim Maughan, David Fisher","doi":"10.1186/s13104-026-07888-2","DOIUrl":"10.1186/s13104-026-07888-2","url":null,"abstract":"<p><strong>Objectives: </strong>To describe the steps taken in the creation of a Data Pack containing clinical data from the FOCUS4 randomized controlled trial in colorectal cancer, representing a case study of clinical trial data access and sharing.</p><p><strong>Data description: </strong>The FOCUS4 trial recruited 1434 metastatic colorectal cancer patients between January 2017 and March 2020 from 94 sites across the United Kingdom (UK). The trial used an adaptive \"umbrella\" design, in which tumour samples from recruited patients underwent molecular testing, the results of which determined into which of multiple parallel randomized allocations they would be eligible to enter. Overall, 361 patients were successfully randomised into one of four \"sub-trials\": FOCUS4-B (6 patients), FOCUS4-C (67 patients), FOCUS4-D (32 patients) and FOCUS4-N (254 patients). After the trial had concluded, we created a Data Pack containing pseudonymised data organised into registration data and follow up data, marked case report forms (CRFs), data dictionary, study protocols and statistical analysis plan. This will help researchers to easily understand the datasets for study replication, further research analysis or to integrate with other existing datasets or repositories.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13640246/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148429767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and psychometric validation of the Hair Health and Care Questionnaire (HHCQ): a KAP-based instrument for young adults.","authors":"Sari Taha, Doha Dababat, Hala Dweikat, Hala Tayeh, Haya Hroub, Rola Abushamma, Annachiara Riccio, Abdulsalam Alkaiyat, Sa'ed H Zyoud","doi":"10.1186/s13104-026-07944-x","DOIUrl":"10.1186/s13104-026-07944-x","url":null,"abstract":"<p><strong>Objective: </strong>Hair plays multiple biological, psychosocial, and cultural roles, impacting psychological well-being and contributing to a rapidly expanding hair care market. This study aimed to validate a questionnaire assessing hair health and care (HHCQ) among young adults.</p><p><strong>Results: </strong>A total of 200 participants completed the questionnaire (mean age = 20.75 years). Item screening and content validation reduced the initial 46 items to 32. No items were removed following face validation, which relied on a qualitative pilot study. Exploratory factor analysis yielded two factors for knowledge (knowledge about routine hair hygiene and care, and knowledge about hair products and procedures) and one factor for attitudes (attitudes toward hair care). The knowledge and attitude factors accounted for 50.3% and 50.6% of the explained variance, respectively. Confirmatory factor analysis revealed that the model was acceptable (CFI = 0.955, TLI = 0.991, RMSEA = 0.077, and SRMR = 0.060). Test-retest reliability showed excellent Intraclass Correlation Coefficients, and Cronbach's alpha coefficients were acceptable. Practice items were treated as a formative index, obviating the need for factor or internal consistency analyses. While the 32-item HHCQ showed basic evidence of validation and reliability, it should be culturally adapted to different settings with additional validation. The questionnaire can be used to guide public health campaigns, policymaking, and clinical practice.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13640304/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148418944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibacterial and wound healing activities of AgNPs, ZnONPs, and Fe₃O₄NPs against Acinetobacter baumannii and Escherichia coli.","authors":"Mohammad Hossein Soleimani, Pegah Shakib, Mohammad Reza Zolfaghari, Ashkan Dirbaziyan, Reza Heidari, Mohsen Chamanara, Saeed Khoshnood, Faeze Fallahi","doi":"10.1186/s13104-026-07889-1","DOIUrl":"10.1186/s13104-026-07889-1","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to evaluate the individual and combined effects of silver nanoparticles (AgNPs), zinc oxide nanoparticles (ZnO-NPs), and iron oxide nanoparticles (Fe₃O₄-NPs) on wound healing in a rat model of infection with Acinetobacter baumannii and Escherichia coli, and to compare their efficacy with a standard antibiotic treatment.</p><p><strong>Results: </strong>AgNPs demonstrated the strongest antibacterial growth inhibition in vitro, while ZnO-NPs showed limited antibacterial activity under the tested conditions. Combination assays indicated enhanced bacterial growth inhibition for AgNP + Fe₃O₄-NPs, whereas ZnO-NPs did not increase antibacterial inhibition in vitro. Nanoparticle-treated wounds showed faster healing than controls in rat models infected with E. coli and A. baumannii. Complete wound closure by day nine was observed in the Ag + ZnO and Fe₃O₄ groups for E. coli infection and in the Ag, ZnO, and Ag + ZnO groups for A. baumannii. Wound-healing rates reached 100% in the Fe₃O₄ and Ag + ZnO groups, which was significantly higher than in untreated controls. Histological evaluation revealed no necrosis in any group, while treated wounds exhibited increased granulation tissue formation and reduced inflammation. Overall, the Ag + ZnO nanoparticle combination showed a synergistic effect, leading to superior antibacterial activity and accelerated wound repair.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13386800/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148418906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Concomitant caffeine exposure and chronic sleep deprivation impair male sexual performance and fecundity via monoaminergic and hypothalamic-pituitary-adrenal/gonadal axis dysregulation in rats.","authors":"Edem Ekpenyong Edem, Christopher Oloruntoba Akintayo, Kate Eberechukwu Nebo, Chiamaka Faith Daniel, Kelechi Favour Chinyere, Linus Anderson Enye","doi":"10.1186/s13104-026-07946-9","DOIUrl":"10.1186/s13104-026-07946-9","url":null,"abstract":"<p><strong>Objective: </strong>Chronic sleep deprivation (SD) and caffeine consumption individually impair male reproductive function; however, the combined impact of simultaneous exposure on reproductive neuroendocrinology remains largely unexplored. This study investigated the effects of concomitant exposure to a novel Unpredictable Chronic Sleep Deprivation (CUSD) paradigm and high-dose caffeine on hypothalamic monoaminergic neurotransmission, seminal indices, and hypothalamic-pituitary-adrenal/gonadal (HPA/HPG) axis activity in adult male Long-Evans rats.</p><p><strong>Results: </strong>Twenty male Long-Evans rats were exposed to either CUSD, caffeine, or a combination of CUSD and caffeine. Combined CUSD and caffeine exposure significantly increased intromission latency and reduced intromission number, mounting latency, and mounting frequency compared to controls. Seminal parameters, including sperm motility, morphology, viability, and count, were markedly impaired in the CUSD and CUSD+caffeine groups. Serum GnRH, testosterone, LH, and FSH were significantly reduced, while corticosterone was significantly elevated across treatment groups, with the most pronounced effects in the CUSD+caffeine group. Hypothalamic serotonin and dopamine were significantly depleted in the CUSD and CUSD+caffeine groups. Nitrergic stress, evidenced by elevated iNOS and NO levels, was observed in hypothalamic and testicular tissues. These findings suggest that simultaneous exposure to CUSD and high-dose caffeine synergistically impairs male sexual performance and fecundity by dysregulating monoaminergic neurotransmission and HPA/HPG axis activity.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13632413/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148410520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}