BMC Research Notes最新文献_第3页

Methanobrevibacter smithii strain U29 whole genome sequence delineates M. smithii intermediate cell variants. 史密斯甲烷预菌菌株U29全基因组序列描述了史密斯甲烷预菌中间细胞变异。

IF 1.7

BMC Research Notes Pub Date : 2025-10-01 DOI: 10.1186/s13104-025-07444-4

Ihab Malat, Vincent Bossi, Michel Drancourt, Ghiles Grine, Raymond Ruimy

{"title":"Methanobrevibacter smithii strain U29 whole genome sequence delineates M. smithii intermediate cell variants.","authors":"Ihab Malat, Vincent Bossi, Michel Drancourt, Ghiles Grine, Raymond Ruimy","doi":"10.1186/s13104-025-07444-4","DOIUrl":"10.1186/s13104-025-07444-4","url":null,"abstract":"Background: Methanobrevibacter smithii (M. smithii), the predominant methanogen in the human digestive tract, plays a key role in methane production. Despite its importance, the genomic diversity of M. smithii is poorly characterised, especially in extra-digestive sites such as the urinary and respiratory tracts, and the blood. Understanding this diversity would help unravel its potential role in human health and diseases.Results: We report the genome of M. smithii strain U29, isolated from urine, expanding the known diversity of the species. The M. smithii U29 genome (scaffold level; 1̵822‒124-bp, 1745 protein-coding sequences) lacks Candidatus Nanopusillus sequences, unlike digestive tract strains. Comparative analysis has revealed a high similarity (99.86% ANI) with the reference M. smithii strain ATCC 35,061, although U29 contains 71 unique coding sequences including 12/71 (13 200-bp; 69% of the total extra-material size) with demonstrated Siphoviridae viral ancestry. Accordingly, M. smithii U29 has been identified as an intermediate M. smithii cell variant, exhibiting genomic traits potentially conferring adaptability to the urinary tract.Conclusion: This study enhances our understanding of M. smithii genomic diversity and highlights the presence of viral sequences in the urinary tract M. smithii strain U29. These findings open up a hypothesis that viral integration may play a role in M. smithii mucosae colonisation and dynamics, underscoring the need for further investigations into the mechanisms underlying its tissue translocation and potential health implications.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"414"},"PeriodicalIF":1.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12487256/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Experiences of family caregivers of patients with traumatic brain injury: a study in the Tamale metropolis. 创伤性脑损伤患者的家庭护理经验：一项在Tamale大都市的研究。

IF 1.7

BMC Research Notes Pub Date : 2025-10-01 DOI: 10.1186/s13104-025-07472-0

Marese Kanyeti Bugri, Gilbert Ti-Enkawol Nachinab

{"title":"Experiences of family caregivers of patients with traumatic brain injury: a study in the Tamale metropolis.","authors":"Marese Kanyeti Bugri, Gilbert Ti-Enkawol Nachinab","doi":"10.1186/s13104-025-07472-0","DOIUrl":"10.1186/s13104-025-07472-0","url":null,"abstract":"Background: Traumatic brain injury is a major global health issue, impacting all aspects of life, including the psychosocial well-being of affected individuals and their families. This study aimed to explore the experiences of family caregivers of Patients with TBI in Tamale Metropolis.Methods: The study used a descriptive exploratory qualitative approach to understand the experiences of family caregivers of patients with TBI in Tamale Metropolis. Purposive sampling technique was used to select ten family caregivers, and face-to-face interviews were conducted using a semi-structured guide. Data was analyzed using inductive thematic analysis.Findings: The findings revealed that participants experienced psychological effects, including stress, anxiety, and satisfaction in caring for their TBI relatives, as well as social effects like socializing issues, poor relationships, and job-related challenges. They coped through strategies such as adjustments, divine intervention, support from family and friends.Conclusion: The study lays the foundation for future research on the experiences of family caregivers of TBI survivors in Tamale. It also highlights the need for health providers to focus on educating and supporting these caregivers.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"417"},"PeriodicalIF":1.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12486957/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of a ultraviolet (UV)-equipped waste box in reducing bacterial contamination in laboratory waste. 配备紫外线（UV）的废物箱在减少实验室废物细菌污染方面的效果。

IF 1.7

BMC Research Notes Pub Date : 2025-10-01 DOI: 10.1186/s13104-025-07375-0

Slamet Wardoyo, Deddy Adam, Taufik Anwar, Jessica Juan Pramudiatia

{"title":"Effectiveness of a ultraviolet (UV)-equipped waste box in reducing bacterial contamination in laboratory waste.","authors":"Slamet Wardoyo, Deddy Adam, Taufik Anwar, Jessica Juan Pramudiatia","doi":"10.1186/s13104-025-07375-0","DOIUrl":"10.1186/s13104-025-07375-0","url":null,"abstract":"Introduction: Infectious waste handling is a serious problem in healthcare, especially laboratory units. With the increase in research activities, innovative designs are needed that can reduce the risk of contamination and effective solutions are needed for laboratory waste management. Management of infectious solid waste often involves expensive techniques such as incineration, chemical treatment or autoclaving to minimize hazardous substances. Waste left over from laboratory testing activities requires special treatment before disposal. This study aims to test the ability of the waste box equipped with Ultraviolet (UV) in inhibiting the growth of Staphyloccus aereus.Methods: This study used a simple 2 mm thick acrylic bin model with a Black box height of 50 cm and a base of 1600 cm2, equipped with Ultra Violet (UV) C (wavelength 200-280) to inactivate some viruses and bacteria. The bacteria used was Staphylococcus aureus which was characterized through Gram staining, morphology, and biochemical tests.Results: The study demonstrated the effectiveness of using ultraviolet lamps in the waste box to reduce the growth of staphylococcus aureus bacteria, which is an indicator of infectious waste bacteria.Conclusion: In conclusion, the use of mini-bin bins with UV lamps can be an effective alternative in handling infectious waste in testing laboratories, but further testing is needed for the recovery of other bacteria, viruses, and fungi.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"416"},"PeriodicalIF":1.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12486523/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Continuous passive motion for prevention of ankle contracture and muscle loss in mechanically ventilated ICU patients. 持续被动运动预防ICU机械通气患者踝关节挛缩和肌肉丢失。

IF 1.7

BMC Research Notes Pub Date : 2025-10-01 DOI: 10.1186/s13104-025-07457-z

Chen-Chun Lin, Yi-Jia Lin, Hsien-Chun Wang, Wei-Chun Hsu

{"title":"Continuous passive motion for prevention of ankle contracture and muscle loss in mechanically ventilated ICU patients.","authors":"Chen-Chun Lin, Yi-Jia Lin, Hsien-Chun Wang, Wei-Chun Hsu","doi":"10.1186/s13104-025-07457-z","DOIUrl":"10.1186/s13104-025-07457-z","url":null,"abstract":"Objective: This prospective, within-patient controlled study aimed to evaluate the effects of continuous passive motion therapy on ankle mobility and muscle morphology in mechanically ventilated ICU patients-a population vulnerable to ICU-acquired weakness and joint contractures.Results: Twelve ventilated patients completed the protocol. The ankle treated with continuous passive motion therapy showed a significant improvement in dorsiflexion passive range of motion, increasing from 9.90° [IQR: 6.20-13.15°] to 12.99° [IQR: 9.07-20.20°] (p = 0.004), while the control ankle showed no significant change (p = 0.388). The increase in passive range of motion was significantly greater in the continuous passive motion treated ankle compared with the control (4.18° vs. 0.42°, p = 0.028). No significant between-limb differences were observed in tibialis anterior muscle thickness, cross-sectional area, or pennation angle. Echointensity increased in both limbs without group differences. These findings suggest that continuous passive motion can be applied as an early intervention to preserve ankle mobility in ICU patients. Although short-term muscle morphology changes were not significant, passive range of motion gains suggest continuous passive motion may help prevent contractures and support early rehabilitation during critical illness.Trial registration: ClinicalTrials.gov NCT06944431, registered on April 25, 2025. Retrospectively registered.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"409"},"PeriodicalIF":1.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12486782/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reproductive autonomy of visually impaired women: a cross-sectional study in Coimbatore and Tiruchirappalli districts, Tamil Nadu. 视障妇女的生殖自主：泰米尔纳德邦哥印拜陀和蒂鲁奇拉帕利地区的横断面研究。

IF 1.7

BMC Research Notes Pub Date : 2025-10-01 DOI: 10.1186/s13104-025-07496-6

Sampath Kumar Srinivasan, Pitchaimani Govindharaj, Prabu Gopal

{"title":"Reproductive autonomy of visually impaired women: a cross-sectional study in Coimbatore and Tiruchirappalli districts, Tamil Nadu.","authors":"Sampath Kumar Srinivasan, Pitchaimani Govindharaj, Prabu Gopal","doi":"10.1186/s13104-025-07496-6","DOIUrl":"10.1186/s13104-025-07496-6","url":null,"abstract":"Objectives: Reproductive autonomy is a fundamental human right, yet it remains a complex issue for visually impaired women. Therefore, this study aims to explore reproductive autonomy and examine the factors associated with reproductive autonomy among visually impaired women.Results: A cross-sectional study was carried out in Tamil Nadu, India, involving 333 visually impaired women aged 18-44 (36.09 ± 5.97) from two districts. The study used a Reproductive Autonomy Scale (RAS) to assess reproductive autonomy, which comprises decision-making, freedom from coercion, and communication domains. The respondents had mean scores of 2.13 for decision-making, 2.05 for coercion, 3.74 for communication. The study found no significant differences in age, education, occupation, house ownership, community, and religion. Significant differences were found in the number of children across all domains, and the total RAS scores indicated that women with two or more children had higher reproductive autonomy. In spouse's disability, spouses with disabilities scored higher in decision-making domain compared to spouses without disabilities. The study concluded that the visually impaired women had a higher degree of reproductive autonomy. The results highlight that most women experience shared reproductive decision-making and supportive communication with their partners, with minimal instances of coercion.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"413"},"PeriodicalIF":1.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12487622/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study of the relationship between daily alcohol intake and serum 25(OH) vitamin D concentrations in a sample of healthy young Cameroonian men. 喀麦隆健康年轻男性样本中每日酒精摄入量与血清25（OH）维生素D浓度之间关系的研究

IF 1.7

BMC Research Notes Pub Date : 2025-10-01 DOI: 10.1186/s13104-025-07466-y

Jan René Nkeck, Daniela Tinking Tchotsoua, Rosine Eliscar Yassang Noubet, Doris Bibi Essama, Baudelaire Fojo, Wulfran Nganou Tetsoguim, Wilson Chia Tamko, Falmata Amazia, Vicky Jocelyne Ama Moor, Madeleine Ngandeu-Singwé

{"title":"Study of the relationship between daily alcohol intake and serum 25(OH) vitamin D concentrations in a sample of healthy young Cameroonian men.","authors":"Jan René Nkeck, Daniela Tinking Tchotsoua, Rosine Eliscar Yassang Noubet, Doris Bibi Essama, Baudelaire Fojo, Wulfran Nganou Tetsoguim, Wilson Chia Tamko, Falmata Amazia, Vicky Jocelyne Ama Moor, Madeleine Ngandeu-Singwé","doi":"10.1186/s13104-025-07466-y","DOIUrl":"10.1186/s13104-025-07466-y","url":null,"abstract":"Introduction: The association between alcohol consumption and vitamin D status in young men remains controversial. Few data are available from sub-Saharan Africa, although necessary for better prevention of metabolic bone disease in adulthood. This study aimed to analyze the relationship between regular alcohol consumption and vitamin D status in young Cameroonian men.Methods: It was a cross-sectional study on healthy males aged 18 to 45 with regular alcohol consumption within the last three months. We assessed their ethylic index (EI), hematological and hepatic biomarkers of chronic alcohol consumption, and 25 (OH) vitamin D (25(OH)D) concentrations, which were compared according to alcohol consumption (low < 20, moderate 20-39.9 and elevated ≥ 40 g/day) using ANOVA.Results: 155 participants were included, with a mean age of 31 (SD 6) years, a median alcohol consumption duration of 10 [7; 15] years and a median EI of 24 [14; 27] g/day. They mostly consumed beer (95%), with low (42%) and elevated (23%) predominant consumptions. Vitamin D deficiency (< 20ng/mL) was found in 63%. There was no difference in mean 25(OH)D concentrations between the three alcohol consumption groups. No correlation was found between the biomarkers of chronic alcohol consumption studied and 25(OH)D concentrations.Conclusions: There appears to be no relationship between 25(OH)D concentrations and daily alcohol consumption in young Cameroonian men. Nevertheless, more data are needed, including vitamin D metabolism parameters to better understand this relationship.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"415"},"PeriodicalIF":1.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12487613/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neutrophil extracellular traps as a predictive biomarker for severe Mycoplasma pneumonia in children: a clinical observational study. 中性粒细胞胞外陷阱作为儿童重症支原体肺炎的预测性生物标志物：一项临床观察研究

IF 1.7

BMC Research Notes Pub Date : 2025-09-30 DOI: 10.1186/s13104-025-07334-9

Xiaoping Fan, Junsheng Jiang

引用次数: 0

Gingival depigmentation by conservative injectable vitamin C in comparison with scalpel surgery: a randomized controlled split-mouth clinical trial. 保守注射维生素C与手术刀手术牙龈色素沉着的比较：一项随机对照裂口临床试验。

IF 1.7

BMC Research Notes Pub Date : 2025-09-30 DOI: 10.1186/s13104-025-07476-w

Manal M Al-Hajri, Abdulaziz M Tawfik, Redhwan Saleh Al-Gabri, Sadam Ahmed Elayah, Ahmed Yaseen Alqutaibi

{"title":"Gingival depigmentation by conservative injectable vitamin C in comparison with scalpel surgery: a randomized controlled split-mouth clinical trial.","authors":"Manal M Al-Hajri, Abdulaziz M Tawfik, Redhwan Saleh Al-Gabri, Sadam Ahmed Elayah, Ahmed Yaseen Alqutaibi","doi":"10.1186/s13104-025-07476-w","DOIUrl":"10.1186/s13104-025-07476-w","url":null,"abstract":"Background: Gingival pigmentation (GP) is a common aesthetic concern in dentistry. While GP is not harmful, it can cause psychological distress. This study aimed to evaluate the efficacy of vitamin C injection for managing GP compared to the standard scalpel surgery.Methods: The study involved 20 healthy patients aged 19-36. A randomized split-mouth design was used, with vitamin C injections (group 1) on one side and scalpel surgery (group 2) on the other side of the maxilla. Clinical evaluations of gingival depigmentation were conducted preoperatively and at first, second, three weeks and six months postoperatively, using the Gingival Pigmentation Index (GPI), Melanin Pigmentation Index (MPI), Dummett Oral Pigmentation Index (DOPI) and Color Intensity Analysis using ImageJ. Pain and patient satisfaction were measured with a visual analogue scale (VAS) after treatment.Results: The GPI, MPI, and DOPI showed no significant differences in pigmentation between the groups at baseline and after six months (P = 1.0 and 0.80 for GPI; P = 1.00 and 0.54 for MPI; P = 1.00 and 0.59 for DOPI). However, after three weeks, greater depigmentation was noted on the surgical side. The vitamin C group reported lower pain and itching levels (itch: P = 0.02; pain: P = 0.00).Trial registration: This randomized controlled trial was retrospectively registered in the Thai Clinical Trial Registry at 05-7-2024 ( www.thaiclinicaltrials.org ), and its registration number is TCTR20240715003.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"408"},"PeriodicalIF":1.7,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12487293/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145198098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sodium alginate-hyaluronic acid composite particles for doxorubicin delivery: in vitro characterization and cytotoxicity evaluation. 海藻酸钠-透明质酸复合颗粒用于阿霉素递送：体外表征和细胞毒性评价。

IF 1.7

BMC Research Notes Pub Date : 2025-09-30 DOI: 10.1186/s13104-025-07411-z

Zhiyu She, Fangxia Zhang, Duanfei Li, Yong Ji

引用次数: 0

Factors associated with delayed neonatal bathing in Afghanistan: insights from the 2022-2023 multiple indicator cluster survey. 阿富汗新生儿洗澡延迟的相关因素：来自2022-2023年多指标类集调查的见解

IF 1.7

BMC Research Notes Pub Date : 2025-09-30 DOI: 10.1186/s13104-025-07495-7

Muhammad Haroon Stanikzai, Essa Tawfiq, Massoma Jafari, Zainab Ezadi, Abdul Wahed Wasiq, Omid Dadras

{"title":"Factors associated with delayed neonatal bathing in Afghanistan: insights from the 2022-2023 multiple indicator cluster survey.","authors":"Muhammad Haroon Stanikzai, Essa Tawfiq, Massoma Jafari, Zainab Ezadi, Abdul Wahed Wasiq, Omid Dadras","doi":"10.1186/s13104-025-07495-7","DOIUrl":"10.1186/s13104-025-07495-7","url":null,"abstract":"Objectives: Delayed neonatal bathing, defined as postponing the first bath until at least 24 h after birth, is a key component of essential newborn care that helps maintain thermal stability and reduces the risk of hypothermia and infection. This study estimates the national prevalence of delayed neonatal bathing and identifies its determinants in Afghanistan. This study analyzed data from the Afghanistan Multiple Indicator Cluster Survey (MICS) 2022-2023. We fitted multivariable binary logistic regression models to determine factors associated with delayed neonatal bathing.Results: Out of 7,702 women, 68.6% reported delayed neonatal bathing. After adjustment, the odds of delayed bathing were higher among women whose household head completed primary education (AOR 1.38; 95% CI: 1.10-1.73), those delivering in health facilities (AOR 1.57; 95% CI: 1.29-1.91), and women attending 1-3 antenatal care (ANC) visits (AOR 1.29; 95% CI: 1.08-1.53) or 4-7 ANC visits (AOR 1.40; 95%CI: 1.14-1.72) or ≥ 8 ANC visits (AOR 2.05; 95% CI: 1.46-2.87). Conversely, women in the richest wealth quintile were less likely to delay bathing (AOR 0.69; 95% CI: 0.51-0.94). Tailored interventions that leverage antenatal contacts and facility-based care may further improve the adoption of optimal newborn bathing practices in Afghanistan.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"401"},"PeriodicalIF":1.7,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12487455/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145198107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0