BMC Research Notes最新文献

{"title":"Comparative analysis of conventional and IRMS techniques for honey adulteration detection in accordance with ISIRI standards.","authors":"Abbas Alimoradian, Nafiseh Khansari, Mahdi Abdollahi, Behnoosh Ansari Asl, Sonia Asadi, Akbar Yousefi Maghool, Arash Rabiei, Ali Khademi, Mohsen Shamsi","doi":"10.1186/s13104-025-07287-z","DOIUrl":"10.1186/s13104-025-07287-z","url":null,"abstract":"<p><strong>Objective: </strong>This study assesses the comparative performance of Isotope Ratio Mass Spectrometry (IRMS) and conventional techniques in detecting honey adulteration. Standard analytical methods, in accordance with ISIRI guidelines, were evaluated alongside δ¹³C isotopic analysis via IRMS across a dataset of 20 honey samples. Conventional analytical techniques were employed to evaluate parameters such as pre-hydrolysis reducing sugars, sucrose content, the fructose-to-glucose ratio, proline, and hydroxymethylfurfural (HMF). The advanced IRMS technique was utilized to determine δ¹³C values for glucose with high accuracy and sensitivity. The carbohydrate profile of honey, including glucose, fructose, disaccharides, and trisaccharides, was analyzed using LC/IRMS. A comparative assessment of both methods was conducted on twenty honey samples, following ISIRI guidelines.</p><p><strong>Results: </strong>While conventional methods met ISIRI criteria in 18 out of 20 samples, IRMS produced contrasting findings-only 2 samples were identified as genuine and free from adulteration. Statistical evaluation using Prism software revealed a significant discrepancy between the two techniques, with a p-value < 0.05, indicating stronger confidence in IRMS results. The findings highlight the necessity of reconsidering current protocols for honey adulteration detection in order to preserve the purity and credibility of this high-value natural product.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"226"},"PeriodicalIF":1.6,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12096562/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144118903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biofilm formation capacity and Carbapenem-resistance in Acinetobacter-calcoaceticus-baumannii isolated from inpatients in a tertiary care hospital in Nepal.","authors":"Shova Bhandari, Milan Kumar Upreti, Khadga Bikram Angbuhang, Basudha Shrestha, Upendra Thapa Shrestha","doi":"10.1186/s13104-025-07211-5","DOIUrl":"10.1186/s13104-025-07211-5","url":null,"abstract":"<p><strong>Objective: </strong>Acinetobacter calcoaceticus-baumannii complex (ACBC), as an emerging global burden to various clinical infections, has a huge problem in empirical therapy due to the increasing resistance to the majority of antibiotics. The ability of biofilm formation added to its antimicrobial resistance and helped its persistence and survival in the environment. To associate biofilm formation with carbapenem resistance, a hospital-based cross-sectional study was carried out from February 2020 to August 2020 at Kathmandu Model Hospital, Kathmandu, Nepal. ACBC was identified from the clinical samples following standard Microbiological procedures. A modified Kirby-Bauer disk diffusion method was performed to assay the antibiotic susceptibility testing of ACBC isolates to various antibiotic classes. A quantitative adherence assay was used to determine the biofilm assay. A conventional Polymerase Chain Reaction (PCR) method was used to find the targeted biofilm-related genes, Bap, csuE, and bla_PER1 using specific primers.</p><p><strong>Results: </strong>Out of 665 different clinical samples, bacterial growth was observed in 281 (42.3%) clinical samples. Of these, 32 (11.4%) isolates were identified as ACBC. Out of 32 ACBC isolates, 29 (90.6%) of which were carbapenem-resistant. All carbapenem-resistant ACBC isolates were found to be sensitive to Polymixin B and Colistin. Out of 29 CR-ACBC, 17.2% of isolates were resistant to Tigecycline. The majority of ACBC isolates (93.8%) were multidrug-resistant (MDR) while 13 (40.6%) of isolates were extensively drug-resistant (XDR). A total of 31 ACBC isolates were biofilm producers, out of which 2 were strong biofilm producers followed by 8 moderate, and 21 were weak biofilm producers. The occurrence of biofilm-forming genes; Bap, csuE, and bla_PER1 genes were found to be 65.6%, 65.6%, and 56.3% respectively among ACBC clinical isolates. A significant association was observed between carbapenem resistance, biofilm formation, and biofilm-related genes.</p><p><strong>Conclusion: </strong>The higher rate of MDR and XDR ACBC isolates associated with biofilm formation in the study alarms the ACBC-related infection in clinical settings among inpatients. The hospital environment and clinical equipment are potential sources of biofilm-forming isolates. Hence, the effective sterilization of clinical equipment and hospital environment are utmost and a strong policy should be made to prescribe the proper antibiotic based on antibiogram profile to fight against an emerging threat of ACBC infections.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"225"},"PeriodicalIF":1.6,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12093812/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144118901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of high N-terminal prohormone of brain natriuretic peptide levels and associated factors among community-dwelling older adults aged over 75 years (The SONIC study): a cross-sectional study.","authors":"Saya Terada, Kayo Godai, Mai Kabayama, Michiko Kido, Yuya Akagi, Hiroshi Akasaka, Yoichi Takami, Takeshi Nakagawa, Saori Yasumoto, Yasuyuki Gondo, Kazunori Ikebe, Yasumichi Arai, Yukie Masui, Takumi Hirata, Koichi Yamamoto, Kei Kamide","doi":"10.1186/s13104-025-07280-6","DOIUrl":"10.1186/s13104-025-07280-6","url":null,"abstract":"<p><strong>Objectives: </strong>Considering the heart failure (HF) pandemic, numerous older adults in the community may exhibit potential cardiac overload or asymptomatic HF without apparent HF diagnosis. This study aimed to examine the distribution of serum N-terminal prohormone of brain natriuretic peptide (NT-proBNP) levels in community-dwelling old age adults aged ≥ 75 years, and to investigate the associated factors for each NT-proBNP classification.</p><p><strong>Results: </strong>A cross-sectional analysis revealed that 52.0% of 611 participants had NT-proBNP ≥ 125 pg/mL. Multinomial logistic regression analysis showed that female sex, older age (80s and 90s), and uncontrolled high blood pressure were significantly associated with 125 ≤ NT-proBNP < 300 pg/mL, while older age (80s and 90s), coronary artery disease, atrial fibrillation, and renal dysfunction were significantly associated with NT-proBNP ≥ 300 pg/mL. Independent association between higher salt intake and NT-proBNP ≥ 300 pg/mL was also observed. Appropriate management of common HF risk factors, such as uncontrolled high blood pressure and high salt intake, is crucial to prevent the progression of overt HF.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"224"},"PeriodicalIF":1.6,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12090677/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of cardiovascular and cerebral disease risk trends before and during the COVID-19 transition phase in Golestan province.","authors":"Mohammad-Ali Jahani, Somayeh Safaie, Mansooreh Gharayagh-Zandi, Seyed-Amir Soltani, Seyedeh-Nikoo Hashemi, Amir-Reza Mahmoudi, Ghahraman Mahmoudi","doi":"10.1186/s13104-025-07283-3","DOIUrl":"10.1186/s13104-025-07283-3","url":null,"abstract":"<p><strong>Objective: </strong>Morbidity and mortality caused by cardiovascular and cerebrovascular diseases are increasing worldwide. This study aimed to analyze the factors affecting the risk assessment of cardiovascular and cerebrovascular diseases before COVID-19 and during the COVID-19 transition phase.</p><p><strong>Results: </strong>Among 132,305 individuals (mean age: 50.11 ± 12.21 years), 65.84% were women. Regression analysis indicated that age, overweight, smoking, diabetes, hypertension, and high cholesterol significantly increased 10-year cardiovascular disease risk (p < 0.001). No significant trend in risk levels was found between pre-COVID-19 and COVID-19 transition periods (p = 0.063). Given the impact of these factors, national-level planning, appropriate policies, and intersectoral coordination are essential to reduce cardiovascular and cerebrovascular risk.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"223"},"PeriodicalIF":1.6,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12087107/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144101533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epstein-Barr virus nuclear antigen 1 (EBNA1) increases the expression levels of MDM2 and MDM4 genes in HeLa cells: a review on MDM2 and MDM4 roles in cancer.","authors":"Seyed Mohammad Ali Hashemi, Amir Hossein Alipour, Sima Emamifar, Ali Farhadi, Jamal Sarvari","doi":"10.1186/s13104-025-07275-3","DOIUrl":"10.1186/s13104-025-07275-3","url":null,"abstract":"<p><strong>Objective: </strong>Epstein-Barr virus nuclear antigen 1 (EBNA1) is a key viral protein expressed in all latency phases and EBV-associated tumors. It can modulate the expression of various host and viral genes. This study aimed to investigate the impact of EBNA1 on the expression levels of two cellular genes involved in p53 pathway regulation-MDM2 and MDM4-in HeLa cells. This investigation was conducted as part of our broader research on EBV-related oncogenic mechanisms.</p><p><strong>Results: </strong>HeLa cells were transfected with either an EBNA1-expressing plasmid or a control plasmid. Gene expression levels of MDM2 and MDM4 were analyzed using real-time PCR. The results demonstrated a statistically significant increase in MDM4 expression in EBNA1-transfected cells compared to controls (p = 0.028). Although MDM2 expression was also elevated, the difference was not statistically significant (p = 0.11). These findings suggest that EBNA1 may play a role in cervical cancer development by upregulating genes that inhibit p53 tumor suppressor activity.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"221"},"PeriodicalIF":1.6,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12084995/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144092798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validity and reliability of the persian version of the dyspnea-12 questionnaire in assessing dyspnea among COPD patients.","authors":"Ehsan Alishapour, Mohammad Ali Nayeri, Razie Bahrami, Alireza Haghshenas, Samrad Mehrabi","doi":"10.1186/s13104-025-07290-4","DOIUrl":"10.1186/s13104-025-07290-4","url":null,"abstract":"<p><strong>Objective: </strong>Dyspnea is a distressing symptom of Chronic Obstructive Pulmonary Disease (COPD). The Dyspnea-12 questionnaire, a well-established instrument for assessing different dimensions of dyspnea validated in multiple languages, lacked a Persian version. This study aimed to adapt and validate a Persian version of Dyspnea-12.</p><p><strong>Results: </strong>The Persian version of Dyspnea-12 demonstrated excellent reliability (Cronbach's alpha = 0.982, Composite Reliability = 0.985). Criterion validity analysis strongly correlated with Dyspnea-12 and CAT scores (ρ = 0.698, p < 0.001). Factor analysis confirmed a single-factor structure consistent with the original version. Inter-item correlations ranged from 0.3 to 0.9. Construct validity indices indicated a satisfactory model fit (CFI = 0.904, SRMR = 0.044), though RMSEA (0.188) suggested areas for improvement. Pulmonary function analysis revealed significant associations between FEV₁ and Dyspnea-12 scores (p = 0.042) and FVC (p = 0.017), linking dyspnea severity with lung function decline.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"222"},"PeriodicalIF":1.6,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12085038/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144092874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of Sesamia nonagrioides and Fusarium verticillioides on carbon elemental and isotopic composition in maize stem piths.","authors":"Elisa Fernández-Descalzo, Lorena Álvarez-Iglesias, Ana Butrón, Serafín J González-Prieto","doi":"10.1186/s13104-025-07278-0","DOIUrl":"10.1186/s13104-025-07278-0","url":null,"abstract":"<p><p>The stem borer Sesamia nonagrioides and the fungus Fusarium verticillioides are frequently present in maize. However, their interaction with this crop and their effects on its physiology remain poorly understood. This study explores the combined impact of these two organisms on carbon composition and δ¹³C content in the stem pith. Eight genetically distinct maize lines (A239, A509, A630, A637, EP42, EP77, EP125, PB130) were subjected to four treatments: an untreated control (UC), infection by F. verticillioides (FV), attack by S. nonagrioides (SN), and infection by F. verticillioides and infestation by S. nonagrioides (FS). Results show moderate variation in δ¹³C values between UC genotypes (-12.6 to -13.1‰, with the exception of line EP77 at -13.8‰), with minor differences related to their inbred resistance to the insect and fungus. Insect infestation results in a noticeable reduction in δ¹³C (0.6‰), but this decrease is partially attenuated in plants previously colonized by the fungus, suggesting an influence of the fungus on the maize's defensive response. In addition, the analysis of ¹³C isotopic composition and carbon signatures provide key elements for a better understanding of maize defence mechanisms. To our knowledge, this study is the first to explore the impact of Sesamia and Fusarium, and their interaction, on carbon metabolism in different maize genotypes.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"219"},"PeriodicalIF":1.6,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12082849/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144085831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Measuring and visualizing scattered x-rays using red-green-blue (RGB) heat maps during extracorporeal membrane oxygenation in the intensive care unit.","authors":"Tomihiko Daioku, Fumiko Oishi, Masanao Kobayashi, Naoko Arakawa, Harumi Ejiri","doi":"10.1186/s13104-025-07286-0","DOIUrl":"10.1186/s13104-025-07286-0","url":null,"abstract":"<p><strong>Objective: </strong>This study investigated the continuous risks of scattered radiation associated with a series of procedures-from extracorporeal membrane oxygenation (ECMO) cannulation through to enteral feeding tube insertion-in an intensive care unit (ICU) setting by visualizing the dose distribution using a red-green-blue (RGB) color map.</p><p><strong>Results: </strong>The scattered radiation doses were measured at 80 points around a tissue-equivalent phantom using calibrated nanoDot dosimeters, and an RGB color map was generated to visualize the dose intensity. Radiation doses near the X-ray source reached 783.6 µSv/hour at 50 cm, exceeding annual public exposure limits within 1 h. These findings emphasize the importance of using appropriate radiation protection equipment, suggesting that distance is a key factor in reducing the ICU exposure risk. They also offer practical guidance for planners involved in radiation safety management in hospital settings.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"220"},"PeriodicalIF":1.6,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12084999/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144085833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Barriers to home-based physical activity and predictors of activity levels among women with high sedentary habits: an explanatory mixed-methods study.","authors":"Malihe Noori-Sistani, Hamid Allahverdipour, Mohammad Vahedian-Shahroodi, Mahta Eskandarnejad, Nahid Ashkriz, Zeinab Javadivala","doi":"10.1186/s13104-025-07243-x","DOIUrl":"10.1186/s13104-025-07243-x","url":null,"abstract":"<p><strong>Objective: </strong>Understanding barriers to home-based physical activity is crucial for developing strategies to increase participation among women with high sedentary habits. This study aims to comprehensively scrutinize these barriers and predictor factors of physical activity levels, utilizing an explanatory mixed methods design. The quantitative phase involved 537 women, who completed a researcher-made questionnaire and the International Physical Activity Questionnaire (IPAQ) to assess physical activity levels, predictor factors, and barriers. The qualitative phase engaged 12 participants through in-depth interviews to gain a deeper understanding of barriers. Chi-square statistical tests, multinomial logistic regression, and content analysis were used.</p><p><strong>Results: </strong>83.8% of women were in the inactive and low-activity category. The main barriers to physical activity included not prioritizing exercise, insufficient time, household responsibilities, and a deficit in motivation. Predictors included environmental barriers (P = 0.009, β = 0.701), social obstacles (P ≤ 0.001, β = 1.179), and lack of motivation (P ≤ 0.001, β = 1.836), all of which significantly impact the level of moderate to vigorous physical activity. The qualitative analysis classified barriers into three categories: personal, social, and environmental. Interventions such as community programs, awareness campaigns, and improved infrastructure are crucial. Health policymakers can take action with targeted strategies to remove barriers and promote women's physical activity.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"217"},"PeriodicalIF":1.6,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12079843/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genomic dataset of multidrug-resistant Klebsiella quasipneumoniae from Indonesia.","authors":"Nastiti Intan Permata Sari, Putu Yuliandari, Ajeng Kusumaningtyas Pramono, Dwi Tyastuti, Abdul Hadi Furqoni, Fitriana Fitriana, Sunarno Sunarno, Dewi Setyowati, Ni Luh Putu Indi Dharmayanti","doi":"10.1186/s13104-025-07269-1","DOIUrl":"10.1186/s13104-025-07269-1","url":null,"abstract":"<p><strong>Objectives: </strong>Klebsiella pneumoniae is a free-living bacterium found anywhere, including soil, water, and various types of plants, animals, and humans. Due to identical biochemical test results, Klebsiella quasipneumoniae, a member of the Klebsiella pneumoniae complex, is often misidentified as Klebsiella pneumoniae. This distinct species can be accurately identified solely through whole-genome sequencing. This bacterium poses a significant public health threat due to its increasing antibiotic resistance, ability to cause severe disease, and potential for community-acquired and hospital-acquired infections. However, there was no previous report of K. quasipneumoniae from Indonesia. Subsequent research focusing on antimicrobial-resistant gene analysis, virulence determinants, evolutionary relationship, and transmission pathways based on this dataset will enhance understanding of this species and their differences with other Klebsiella pneumoniae complex organisms.</p><p><strong>Data description: </strong>We present a whole genome sequencing of four Klebsiella quasipneumoniae isolated from hospital wastewater in Jakarta, Indonesia. Initial bacterial identification was conducted which showed Klebsiella pneumoniae. However, the whole genome Average Nucleotide Identity (wgANI) was found to be Klebsiella quasipneumoniae. The genome size of Klebsiella quasipneumoniae I1-1, I1-3, I5-2, and I5-3 isolates were 5.4 Mb (GC = 57.72%), 5.5 Mb (GC = 57.72%), 5.4 Mb (GC = 57.73%), and 5.5 Mb (GC = 57.72%), respectively. Sequence data has been deposited in the GenBank database.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"218"},"PeriodicalIF":1.6,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12083092/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}