Continuous passive motion for prevention of ankle contracture and muscle loss in mechanically ventilated ICU patients.

IF 1.7 Q2 MULTIDISCIPLINARY SCIENCES

BMC Research Notes Pub Date : 2025-10-01 DOI:10.1186/s13104-025-07457-z

Chen-Chun Lin, Yi-Jia Lin, Hsien-Chun Wang, Wei-Chun Hsu

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引用次数: 0

Abstract

Objective: This prospective, within-patient controlled study aimed to evaluate the effects of continuous passive motion therapy on ankle mobility and muscle morphology in mechanically ventilated ICU patients-a population vulnerable to ICU-acquired weakness and joint contractures.

Results: Twelve ventilated patients completed the protocol. The ankle treated with continuous passive motion therapy showed a significant improvement in dorsiflexion passive range of motion, increasing from 9.90° [IQR: 6.20-13.15°] to 12.99° [IQR: 9.07-20.20°] (p = 0.004), while the control ankle showed no significant change (p = 0.388). The increase in passive range of motion was significantly greater in the continuous passive motion treated ankle compared with the control (4.18° vs. 0.42°, p = 0.028). No significant between-limb differences were observed in tibialis anterior muscle thickness, cross-sectional area, or pennation angle. Echointensity increased in both limbs without group differences. These findings suggest that continuous passive motion can be applied as an early intervention to preserve ankle mobility in ICU patients. Although short-term muscle morphology changes were not significant, passive range of motion gains suggest continuous passive motion may help prevent contractures and support early rehabilitation during critical illness.

Trial registration: ClinicalTrials.gov NCT06944431, registered on April 25, 2025. Retrospectively registered.

查看原文本刊更多论文

持续被动运动预防ICU机械通气患者踝关节挛缩和肌肉丢失。

目的：本前瞻性、患者内部对照研究旨在评估持续被动运动治疗对机械通气ICU患者踝关节活动度和肌肉形态的影响。ICU患者易发生ICU获得性无力和关节挛缩。结果：12例通气患者完成了方案。连续被动运动治疗组踝关节背屈被动活动范围明显改善，从9.90°[IQR: 6.20-13.15°]增加到12.99°[IQR: 9.07-20.20°](p = 0.004)，而对照组踝关节无显著变化（p = 0.388）。与对照组相比，接受持续被动运动治疗的踝关节被动活动范围的增加明显更大（4.18°vs. 0.42°，p = 0.028）。在胫前肌厚度、横截面积或夹角方面，四肢间无显著差异。双肢回声强度增高，无组间差异。这些发现表明，持续被动运动可以作为早期干预措施，以保持ICU患者的踝关节活动能力。虽然短期肌肉形态变化不显著，但被动活动范围的增加表明，持续的被动运动可能有助于预防挛缩，并支持危重疾病期间的早期康复。试验注册：ClinicalTrials.gov NCT06944431，注册于2025年4月25日。回顾注册。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

BMC Research Notes Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (all)

CiteScore

3.60

自引率

0.00%

发文量

363

审稿时长

15 weeks

期刊介绍： BMC Research Notes publishes scientifically valid research outputs that cannot be considered as full research or methodology articles. We support the research community across all scientific and clinical disciplines by providing an open access forum for sharing data and useful information; this includes, but is not limited to, updates to previous work, additions to established methods, short publications, null results, research proposals and data management plans.