BMC Research Notes最新文献_第6页

Sex classification accuracy through machine learning algorithms - morphometric variables of human ear and nose. 性别分类准确性通过机器学习算法-人类耳朵和鼻子的形态计量变量。

IF 1.6

BMC Research Notes Pub Date : 2025-04-15 DOI: 10.1186/s13104-025-07185-4

Tej Kaur, Kewal Krishan, Akanksha Sharma, Ankita Guleria, Vishal Sharma

{"title":"Sex classification accuracy through machine learning algorithms - morphometric variables of human ear and nose.","authors":"Tej Kaur, Kewal Krishan, Akanksha Sharma, Ankita Guleria, Vishal Sharma","doi":"10.1186/s13104-025-07185-4","DOIUrl":"https://doi.org/10.1186/s13104-025-07185-4","url":null,"abstract":"Objective: Sex determination is an important parameter for personal identification in forensic and medico-legal examinations. The study aims at predicting sex accuracy from different parameters of ear and nose by using a novel approach of Machine Learning Library, 'PyCaret'.Results: The present research was carried out on 508 participants (264 males and 244 females) aged 18-35 years from north India. Various ear and nose measurements were recorded on each participant. PyCaret employs a train-eval-testing validation approach, yielding a comprehensive output of the model in the form of a table that consolidates the average scores of all models over ten folds, including the respective time values. These models were compared based on performance metrics, and time taken. The logistic regression classifier emerged as the top-performing model, achieving the highest scores of 86.75% for sex prediction accuracy. Nasal breadth has been concluded as the most significant variable in accurate sex prediction. The findings indicate that the majority of the ear and nose characteristics significantly contribute to sexual dimorphism. This novel approach for sex classification can be efficiently used in a variety of forensic examinations and crime scene investigation especially where there is a need for estimation of sex for personal identification.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"169"},"PeriodicalIF":1.6,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11998274/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143965980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Integrating patient metadata and pathogen genomic data: advancing pandemic preparedness with a multi-parametric simulator. 整合患者元数据和病原体基因组数据：用多参数模拟器推进大流行防范。

IF 1.6

BMC Research Notes Pub Date : 2025-04-15 DOI: 10.1186/s13104-025-07207-1

Bonjean Maxime, Ambroise Jérôme, Orchard Francisco, Sentis Alexis, Hurel Julie, Hayes Jessica S, Connolly Máire A, Jean-Luc Gala

{"title":"Integrating patient metadata and pathogen genomic data: advancing pandemic preparedness with a multi-parametric simulator.","authors":"Bonjean Maxime, Ambroise Jérôme, Orchard Francisco, Sentis Alexis, Hurel Julie, Hayes Jessica S, Connolly Máire A, Jean-Luc Gala","doi":"10.1186/s13104-025-07207-1","DOIUrl":"https://doi.org/10.1186/s13104-025-07207-1","url":null,"abstract":"Stakeholder training is essential for handling unexpected crises swiftly, safely, and effectively. Functional and tabletop exercises simulate potential public health crises using complex scenarios with realistic data. These scenarios are designed by integrating datasets that represent populations exposed to a pandemic pathogen, combining pathogen genomic data generated through high-throughput sequencing (HTS) together with patient epidemiological, clinical, and demographic information. However, data sharing between EU member states faces challenges due to disparities in data collection practices, standardisation, legal frameworks, privacy, security regulations, and resource allocation. In the Horizon 2020 PANDEM-2 project, we developed a multi-parametric training tool that links pathogen genomic data and metadata, enabling training managers to enhance datasets and customise scenarios for more accurate simulations. The tool is available as an R package: https://github.com/maous1/Pandem2simulator and as a Shiny application: https://uclouvain-ctma.Shinyapps.io/Multi-parametricSimulator/ , facilitating rapid scenario simulations. A structured training procedure, complete with video tutorials and exercises, was shown to be effective and user-friendly during a training session with twenty PANDEM-2 participants. In conclusion, this tool enhances training for pandemics and public health crises preparedness by integrating complex pathogen genomic data and patient contextual metadata into training simulations. The increased realism of these scenarios significantly improves emergency responder readiness, regardless of the biological incident's nature, whether natural, accidental, or intentional.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"174"},"PeriodicalIF":1.6,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12001515/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143982941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Physicians' views of the use of morphine in palliative care: a cross-sectional survey from a tertiary care centre in Northern Sri Lanka. 医生在姑息治疗中使用吗啡的观点：斯里兰卡北部三级医疗中心的横断面调查。

IF 1.6

BMC Research Notes Pub Date : 2025-04-14 DOI: 10.1186/s13104-025-07247-7

Balasingam Nisahan, Shobika Raviraj, Sancica Navaratnam, Rajeshkannan Nadarajah

{"title":"Physicians' views of the use of morphine in palliative care: a cross-sectional survey from a tertiary care centre in Northern Sri Lanka.","authors":"Balasingam Nisahan, Shobika Raviraj, Sancica Navaratnam, Rajeshkannan Nadarajah","doi":"10.1186/s13104-025-07247-7","DOIUrl":"https://doi.org/10.1186/s13104-025-07247-7","url":null,"abstract":"Background: Palliative care is not readily available in many lower middle-income countries and Sri Lanka is not an exemption for this. Morphine is one of the key drug available for symptoms (pain and dyspnoea) alleviation among palliative care patients. However, due to various reasons, it was noted that morphine drug was underutilised in palliation. No studies have been done to identify reasons for underutilisation in Northern Sri Lanka. As such, this study attempts to identify factors that limit the usage of morphine in palliative care among physicians working at Teaching Hospital, Jaffna.Methods: This cross-sectional survey was conducted among 216 physicians in March-April 2024 using a self-administrated questionnaire distributed to them. Data was analysed using SPSS (29). Self-rated physicians' confident level of morphine initiation in palliative care patients was assessed in the scale of 0-10 and reported in mean with standard deviation (SD).Results: The majority were females (55.1%) and exactly half of the physicians (50.0%) had less than 5 years of working experience. The mean score of the confident level of physicians in initiating morphine for palliative care patients was 4.84+_2.74. Furthermore, mean score was less among females in comparison to males (P-0.005). Just above 50% of them (50.5%) reported that the undergraduate education about pharmacology and clinical usage regarding morphine may be adequate and 15.2% reported that it was not adequate at all.Conclusion: There is a great need for training for physicians on morphine prescribing in palliative care in Northern Sri Lanka. Major reasons for not prescribing morphine among physicians were lack of confident or not familiar with palliative care, shortage of drugs, patient refusal and relative refusal.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"165"},"PeriodicalIF":1.6,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11995557/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular identification and antifungal susceptibility profile of rare and emerging yeast species causing onychomycosis. 引起甲真菌病的罕见和新兴酵母菌的分子鉴定和抗真菌敏感性分析。

IF 1.6

BMC Research Notes Pub Date : 2025-04-14 DOI: 10.1186/s13104-025-07197-0

Ahmad Jabrodini, Esmaeel Eghtedarnejad, Amirmahdi Ghanbarzadeh, Marjan Motamedi, Mohammad Jafari, Mahboobeh Kharazi, Somayeh Yazdanpanah, Hossein Khodadadi

{"title":"Molecular identification and antifungal susceptibility profile of rare and emerging yeast species causing onychomycosis.","authors":"Ahmad Jabrodini, Esmaeel Eghtedarnejad, Amirmahdi Ghanbarzadeh, Marjan Motamedi, Mohammad Jafari, Mahboobeh Kharazi, Somayeh Yazdanpanah, Hossein Khodadadi","doi":"10.1186/s13104-025-07197-0","DOIUrl":"https://doi.org/10.1186/s13104-025-07197-0","url":null,"abstract":"Objectives: Onychomycosis is a nail infection caused by various fungal agents. In recent years, there has been an increase in cases of onychomycosis caused by rare fungi, which are often challenging to identify using conventional methods. Sometimes, these unusual species exhibit different antifungal susceptibility patterns compared to more common yeast species. Therefore, this study aimed to identify rare yeast species causing onychomycosis and assess their antifungal susceptibility profiles.Results: Nineteen rare and emerging yeast isolates, representing seven species, including Candida orthopsilosis (n = 9, 47.36%), Clavispora lusitaniae (formerly Candida lusitaniae) (n = 2, 10.52%), Wickerhamiella pararugosa (formerly Candida pararugosa) (n = 2, 10.52%), Naganishia diffluens (formerly Cryptococcus diffluens) (n = 2, 10.52%), Wickerhamomyces anomalus (n = 2, 10.52%), Cyberlindnera fabianii (n = 1, 5.26%), and Meyerozyma caribbica (formerly Candida fermentati) (n = 1, 5.26%), were identified. Most rare yeast agents exhibited high minimum inhibitory concentration (MIC) values for fluconazole.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"167"},"PeriodicalIF":1.6,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11998136/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143973885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A pilot study on the relationship between thermal habits, chronic inflammation, and arterial stiffness in young adults. 一项关于年轻人热习惯、慢性炎症和动脉僵硬之间关系的初步研究。

IF 1.6

BMC Research Notes Pub Date : 2025-04-14 DOI: 10.1186/s13104-025-07236-w

Masayo Nagai, Akiko Tanaka

{"title":"A pilot study on the relationship between thermal habits, chronic inflammation, and arterial stiffness in young adults.","authors":"Masayo Nagai, Akiko Tanaka","doi":"10.1186/s13104-025-07236-w","DOIUrl":"https://doi.org/10.1186/s13104-025-07236-w","url":null,"abstract":"Objective: Atherosclerotic cardiovascular disease (ASCVD) progresses silently, highlighting the importance of early prevention. This pilot study aimed to examine the relationship between thermal habits-specifically hot-tub bathing-and biomarkers of chronic inflammation, as well as arterial stiffness in young adults.Results: Twenty-five participants were included: 9 males (mean age: 21.78 ± 2.05 years) and 16 females (mean age: 21.0 ± 0.97 years). We assessed hot bathing habits and measured plasma interleukin-6 (IL-6), high-sensitivity C-reactive protein (hsCRP), heat shock protein 70 (HSP70), and brachial-ankle pulse wave velocity (baPWV). IL-6 levels were significantly lower among habitual hot-tub bathers (p = 0.04 overall; p = 0.018 in females). In females, hsCRP tended to be lower with immersion bathing (p = 0.08). No significant differences were observed in hsCRP, HSP70, or baPWV in the overall, male, or female groups. In females, IL-6 negatively correlated with ABI (ρ = -0.543, p = 0.03), and baPWV negatively correlated with bathing duration (ρ = -0.562, p = 0.045). These findings suggest that habitual hot-tub bathing, a culturally embedded and easily implemented habit in Japan, may serve as a lifestyle intervention to reduce inflammation and support ASCVD prevention in young adults.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"166"},"PeriodicalIF":1.6,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11995562/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143962455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tissue-specific changes in expression of Vegfr2 in tumor and normal tissues of lymphoma-bearing BALB/c mice under chronic restraint stress. 慢性抑制应激下带淋巴瘤BALB/c小鼠肿瘤和正常组织中Vegfr2表达的组织特异性变化

IF 1.6

BMC Research Notes Pub Date : 2025-04-14 DOI: 10.1186/s13104-025-07219-x

Alonso A Orozco-Flores, Gloria Romero-Beltrán, Diana Caballero-Hernández, Deyanira Quistián-Martínez, Ricardo Gomez-Flores, Patricia Tamez-Guerra, Cristina Rodríguez-Padilla

{"title":"Tissue-specific changes in expression of Vegfr2 in tumor and normal tissues of lymphoma-bearing BALB/c mice under chronic restraint stress.","authors":"Alonso A Orozco-Flores, Gloria Romero-Beltrán, Diana Caballero-Hernández, Deyanira Quistián-Martínez, Ricardo Gomez-Flores, Patricia Tamez-Guerra, Cristina Rodríguez-Padilla","doi":"10.1186/s13104-025-07219-x","DOIUrl":"https://doi.org/10.1186/s13104-025-07219-x","url":null,"abstract":"Objective: Alteration of the expression of vascular endothelial growth factor (VEGF) and its receptors, VEGFR-1 and VEGFR-2, leads to aberrant angiogenesis in cancer; this is exacerbated by chronic stress. Our main aim was to determine the effect of chronic restraint stress on the expression of Vegfr2, the gene encoding VEGFR-2, in tumor, fat, skeletal muscle and brain in a murine model of lymphoma.Results: We found that both chronic stress and tumor burden alter Vegfr2 expression. Under chronic stress, Vegfr2 is differentially expressed in inguinal adipose tissue, decreasing in tumor-free, and increasing in tumor-bearing animals. In skeletal muscle, brain, and tumor, Vegfr2 expression was upregulated by chronic stress. Adipose tissue, brain and skeletal muscle of tumor-bearing animals also showed changes in Vegfr2 expression during tumor progression. We also found that for skeletal muscle the combination of chronic stress and tumor burden enhances Vegfr2 expression (23-folds).Conclusion: Chronic stress and tumor burden influence Vegfr2 expression in normal and tumoral tissues and their co-occurrence enhances its effect on skeletal muscle.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"168"},"PeriodicalIF":1.6,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11998259/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143977576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of immunomodulatory celecoxsib on the gene expression of inhibitory receptors in dendritic cells generated from monocyte cells. 免疫调节剂塞来昔布对单核细胞生成树突状细胞抑制受体基因表达的影响。

IF 1.6

BMC Research Notes Pub Date : 2025-04-13 DOI: 10.1186/s13104-025-07226-y

Vida Hashemi, Behzad Baradaran, Bahar Naseri, Javad Masoumi, Elham Baghbani, Nazila Alizadeh, Reza Shiri Haris, Arezoo Hosseini

{"title":"The effect of immunomodulatory celecoxsib on the gene expression of inhibitory receptors in dendritic cells generated from monocyte cells.","authors":"Vida Hashemi, Behzad Baradaran, Bahar Naseri, Javad Masoumi, Elham Baghbani, Nazila Alizadeh, Reza Shiri Haris, Arezoo Hosseini","doi":"10.1186/s13104-025-07226-y","DOIUrl":"https://doi.org/10.1186/s13104-025-07226-y","url":null,"abstract":"Autoimmune diseases are characterized by irregular immune responses that disrupt self-tolerance. This research explores the effects of the immunomodulatory drug celecoxib on the expression of immune checkpoint receptors in monocyte-derived dendritic cells (DCs). Key receptors, including CTLA-4, VISTA, BTLA, PDL-1, B7H7, and LAG3, play critical roles in initiating and regulating immune responses and maintaining self-tolerance. Previous studies have highlighted the significance of immune checkpoints in preventing autoimmune conditions, with animal research supporting their effectiveness in immunotherapy. Our findings demonstrate that the upregulation of immune checkpoint receptors can enhance the inhibitory functions of DCs, thereby promoting self-tolerance. As a result, tolerogenic DCs present a promising therapeutic avenue for treating autoimmune diseases. Although these results are promising, further trials are required to validate this approach before it can be applied clinically. This study underscores the potential of targeting immune checkpoint receptors as a therapeutic strategy for autoimmune disorders.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"164"},"PeriodicalIF":1.6,"publicationDate":"2025-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11995585/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143977575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development and evaluation of an online cardiotocography course tailored to LMIC settings: a feasibility study conducted in a tertiary care hospital in Sri Lanka. 开发和评估适合低收入和中等收入国家环境的在线心脏摄影课程：在斯里兰卡一家三级保健医院进行的可行性研究。

IF 1.6

BMC Research Notes Pub Date : 2025-04-12 DOI: 10.1186/s13104-025-07239-7

M Rishard, I Weerasundara, R Fonseka, A de Abrew, M S D Wijesinghe, H Senanayake, M Lazzerini

{"title":"Development and evaluation of an online cardiotocography course tailored to LMIC settings: a feasibility study conducted in a tertiary care hospital in Sri Lanka.","authors":"M Rishard, I Weerasundara, R Fonseka, A de Abrew, M S D Wijesinghe, H Senanayake, M Lazzerini","doi":"10.1186/s13104-025-07239-7","DOIUrl":"https://doi.org/10.1186/s13104-025-07239-7","url":null,"abstract":"Objective: Effective cardiotocography (CTG) training is crucial for accurate interpretation and timely interventions in low-resource settings. This mixed-method study in Sri Lanka developed and assessed an online CTG course to address training gaps and improve neonatal outcomes. The study involved a clinical audit, course development, implementation, and evaluation via the Kirkpatrick model.Results: The audit revealed lapses in CTG documentation, interpretation, and interventions. The posttest scores improved by 40.6% (152.8%), but some participants did not complete the course because of a lack of motivation, time constraints, and inadequate facilities. Postimplementation audits revealed improvements in practices, although uterine contraction documentation and overall impression recording declined. The findings suggest the feasibility and effectiveness of online self-learning courses in improving CTG knowledge and practices in Sri Lanka. However, motivation, incentives, and reinforcement measures are needed for better outcomes.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"163"},"PeriodicalIF":1.6,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11993943/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143954516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Early dysphagia following anterior cervical discectomy and fusion: a centre experience. 颈前路椎间盘切除术和融合术后早期吞咽困难：一项中心经验。

IF 1.6

BMC Research Notes Pub Date : 2025-04-11 DOI: 10.1186/s13104-025-07215-1

Hani Aljohani, Abdulrahman H Alashkar, Mohamed Abdulazim, Yasser Alsequab, Eid Algaman, Almunthir Alyahya, Sultan Alhujilan, Faisal Ahmad Alaboodi

{"title":"Early dysphagia following anterior cervical discectomy and fusion: a centre experience.","authors":"Hani Aljohani, Abdulrahman H Alashkar, Mohamed Abdulazim, Yasser Alsequab, Eid Algaman, Almunthir Alyahya, Sultan Alhujilan, Faisal Ahmad Alaboodi","doi":"10.1186/s13104-025-07215-1","DOIUrl":"https://doi.org/10.1186/s13104-025-07215-1","url":null,"abstract":"Objective: Anterior cervical discectomy and fusion (ACDF) is a commonly performed surgical procedure in patients with cervical spine radiculopathy and/or myelopathy. It's considered safe, but one of its most common complications is postoperative dysphagia, which can negatively impact the patient's quality of life, and increase health costs. In this study, we discuss our experience with post-ACDF dysphagia (PAD) in terms of incidence, risk factors and approach to management.Results: In total, 196 eligible patients were included with a mean age of 50.38 years (SD = 11.18); 107 patients (54.6%) were males, and 89 (45.4%) were females. The incidence of PAD was 5.6% (11/196 patients). No significant association could be found between the development of PAD and the assessed patient-related factors (age, gender, body mass index, and comorbidities) nor surgical factors (number of operated levels, use of anterior plate, operative time).","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"162"},"PeriodicalIF":1.6,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11992851/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143963921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of knowledge, attitudes, and practices of antibiotic resistance among university students in Saudi Arabia. 沙特阿拉伯大学生抗生素耐药性知识、态度和实践评估

IF 1.6

BMC Research Notes Pub Date : 2025-04-11 DOI: 10.1186/s13104-025-07241-z

Rana K Albadrani, Aysha H Alyenbawi, Mody Albalawi, Amnah Obidan, Hayam A Alwabsi, Sahar Khateeb, Ahmed S Aly, Mervat S Mohamed

{"title":"Assessment of knowledge, attitudes, and practices of antibiotic resistance among university students in Saudi Arabia.","authors":"Rana K Albadrani, Aysha H Alyenbawi, Mody Albalawi, Amnah Obidan, Hayam A Alwabsi, Sahar Khateeb, Ahmed S Aly, Mervat S Mohamed","doi":"10.1186/s13104-025-07241-z","DOIUrl":"https://doi.org/10.1186/s13104-025-07241-z","url":null,"abstract":"Objective: Antibiotic resistance is a global health threat, driven by widespread misconceptions and the misuse of antibiotics. This study aims to assess the knowledge, attitudes, and practices of undergraduate students at the University of Tabuk, Saudi Arabia, regarding antibiotic use and resistance, identifying key misconceptions and behaviours contributing to antibiotic resistance.Results: The analysis revealed misconceptions about antibiotic use and resistance among 800 undergraduate students at the University of Tabuk. Approximately 46% of respondents incorrectly believed that antibiotics could treat viral infections, while 23% were uncertain about their effectiveness against bacterial infections. Although 56% acknowledged that antibiotics might lose effectiveness over time, 24% were unsure about the reason. Additionally, 53% mistakenly believed that viruses could develop antibiotic resistance. These findings highlight persistent gaps in understanding among students. Strengthening awareness through workshops and structured interventions could improve knowledge and promote responsible antibiotic use. Addressing these misconceptions is essential to reducing inappropriate antibiotic practices and mitigating the risks associated with antibiotic resistance.","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"161"},"PeriodicalIF":1.6,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11992694/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144062427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0