BMC Research Notes最新文献

{"title":"The accuracy of digital impression with different intraoral scanners on maxillary all on four implants: an in vitro study.","authors":"Hesham M El-Refay, Medhat Sameh Abdelaziz, Nora M Cheta, Mohamed F Abdallah","doi":"10.1186/s13104-025-07235-x","DOIUrl":"https://doi.org/10.1186/s13104-025-07235-x","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to evaluate the effect of 30° angulation of (All-on-four) implants on the accuracy of digital impressions using different intra-oral scanners in the maxillary edentulous arch in terms of trueness and precision.</p><p><strong>Materials and methods: </strong>A maxillary completely edentulous model was 3D printed with four-cylinder holes measuring 4.3*10 mm, creating space for implant analogs at the canines and second premolar areas. The two anterior implants were placed parallel to each other with 0-degree angulation at the site of the canines, while the two posterior implants were placed at the site of the second premolars with 30° distal angulations. Four peek scan bodies were screwed to analogs. The model is scanned using an EOS X5 desktop scanner and set as a reference model. Afterward, three groups of intraoral scanners group 1 (Trios3shape), group 2 (Medit I700), and group 3 (Launca DL-202) were used to scan the model. Seven scans of the model were performed for each scanner following the manufacturer protocol. The trueness and precision of each intraoral scanner were virtually tested using the Gemoagic Control X software program.</p><p><strong>Results: </strong>Regarding trueness, there was a statistically significant deviation between the three intraoral scanners recording 38, 44, and 229 μm for the Trios, Medit I-700, and Launca scanners, respectively, while there was no statistically significant difference in precision between the Trios and Medit I700 scanners.</p><p><strong>Conclusions: </strong>The Trios scanner was the most accurate regarding trueness and precision for recording the maxillary full arch implants, followed by the Medit I-700, and the Launca scanner due to the ability of the Trios scanner to scan the posterior angulated implants as accurately as the anterior straight ones. Also, the scanner technology separately doesn't affect scanning accuracy, but other factors should be taken into consideration such as scanner design and scanner head size.</p><p><strong>Clinical relevance: </strong>The type of intraoral scanner used in full arch cases greatly affects the accuracy of digital impressions, which may affect the fit of future prostheses, so the operator should carefully choose the proper optical scanner.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"186"},"PeriodicalIF":1.6,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12013090/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In vitro RNA-mediated gene silencing of Fusarium oxysporum f.sp. cubense from Ecuador and assessment of RNAi molecule stability in banana plants.","authors":"Ricardo Pacheco, Julio Bonilla, Aracely Paguay, Freddy Magdama, Pablo Chong","doi":"10.1186/s13104-025-07253-9","DOIUrl":"https://doi.org/10.1186/s13104-025-07253-9","url":null,"abstract":"<p><strong>Objective: </strong>Fusarium wilt poses a significant threat to banana production, caused by diverse clonal Fusarium lineages. Given the lack of curative measures, developing effective treatments is crucial. RNA interference (RNAi) technology, utilizing double-stranded RNA (dsRNA) molecules, offers a promising solution. In this study, RNAi was evaluated by silencing the activity of the Beta-tubulin (Focβ-tub), C5 Sterol desaturase (FocERG3) and Chitin synthase 1 (FocChs1) genes in a pathogenic Fusarium strain. Furthermore, we study the potential of dsRNA translocation in 3 months old banana plants at early hours of been spray under greenhouse conditions.</p><p><strong>Results: </strong>In vitro results demonstrated that dsRNA-FocChs1 was more effective in inhibiting spores, with an average IC₅₀ of 156.84 mg/L, compared to dsRNA-Focβ-tub (IC₅₀: 532.7 mg/L), dsRNA-FocERG3 (IC₅₀: 635.59 mg/L), and a positive control (IC₅₀: 243.91 mg/L). A greenhouse test was conducted to evaluate the translocation of dsRNA in banana plants. The results demonstrated that the dsRNA remained on the applied leaf without degradation up to 48 h post-application (hpa). However, no translocation to other plant tissues was detected until the last time point. Further time points should be evaluated to ascertain the dsRNA translocation to other banana plant tissue.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"185"},"PeriodicalIF":1.6,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12013083/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143981310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing professional development in medical residency through a shadow curriculum: an evaluation based on Kirkpatrick model.","authors":"Sahba Fekri, Amin Habibi, Hamed Khani, Samane Babaei, Masomeh Kalantarion","doi":"10.1186/s13104-025-07233-z","DOIUrl":"https://doi.org/10.1186/s13104-025-07233-z","url":null,"abstract":"<p><strong>Introduction: </strong>Current medical residency programs often neglect critical areas of professional development, such as patient safety, stewardship, and effective clinical documentation. This study evaluates the effectiveness of a shadow curriculum designed to enhance these aspects for medical residents.</p><p><strong>Methods: </strong>The shadow curriculum was implemented for first-year residents in ophthalmology, internal medicine, and urology, consisting of an 8-hour workshop covering job encounters, stewardship, patient safety principles, medical documentation, and electronic prescribing. Conducted in 2023 with 22 residents, the evaluation utilized questionnaires, pre- and post-tests, and semi-structured interviews to assess satisfaction and learning outcomes.</p><p><strong>Results: </strong>54.55% of participants with a mean score of 23.66 (SD = 1.97) reported satisfaction with course content, and 63.63% with a mean score of 22.64 (SD = 2.63), were satisfied with the course organization. Pre/post-test results showed a significant knowledge increase (p < 0.001), particularly in antibiotic prescribing and patient safety. Qualitative interviews emphasized on three themes including consumer oriented learning, changing the perspective of teaching and learning, and promotion of self-directed learning.</p><p><strong>Conclusions: </strong>This study highlights the shadow curriculum's effectiveness in improving residents' professional satisfaction and knowledge. By prioritizing learner perspectives and extending opportunities beyond traditional settings, it fosters a personalized learning environment. These findings underscore the need to integrate shadow curricula into medical training to meet evolving educational needs and enhance professional development.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"184"},"PeriodicalIF":1.6,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12009517/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143981476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics of type 2 diabetes patients with overt cardiovascular diseases in Malaysia: the real-world evidence from the National Diabetes Registry.","authors":"Kim Sui Wan, Noran Naqiah Hairi, Feisul Mustapha, Muhammad Fadhli Mohd Yusoff, Mastura Ismail, Foong Ming Moy, Noor Ani Ahmad","doi":"10.1186/s13104-025-07204-4","DOIUrl":"https://doi.org/10.1186/s13104-025-07204-4","url":null,"abstract":"<p><strong>Objective: </strong>The characteristics of diabetes patients with cardiovascular disease (CVD) in Malaysia are not well understood, especially in terms of metabolic control and treatment profiles. We aimed to determine the characteristics of type 2 diabetes patients with CVD in public primary care clinics in Malaysia. A cross-sectional analysis of the baseline information of an established retrospective cohort dataset was done.</p><p><strong>Results: </strong>Among 18,312 patients, 4.1% had CVD. In the multiple logistic regression model, CVD was associated with males, older age, longer diabetes duration, hypertension, dyslipidaemia, nephropathy, insulin, antiplatelet agents, and glycosylated haemoglobin A1c control. In contrast, LDL cholesterol control was less common among patients with CVD. The percentage of patients with CVD who achieved the recommended glycosylated haemoglobin A1c ≤ 8%, blood pressure ≤ 135/75 mmHg, and LDL cholesterol < 1.8 mmol/L were 59.5%, 25.3%, and 13.7%, respectively. Meanwhile, 44.7%, 25.6%, and 42.7% of patients without CVD achieved glycosylated haemoglobin A1c ≤ 7.0%, blood pressure ≤ 135/75 mmHg, and LDL cholesterol ≤ 2.6 mmol/L, respectively. Many patients did not achieve the recommended treatment targets. There are ample opportunities to optimise the quality of diabetes management in primary care settings in Malaysia.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"183"},"PeriodicalIF":1.6,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12007231/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of atherogenic indices and triglyceride-total cholesterol-body weight index (TCBI) with severity of stenosis in patients undergoing angiography: a case-control study.","authors":"Mobina Imannezhad, Farzam Kamrani, Ali Shariatikia, Mahsa Nasrollahi, Hanie Mahaki, Ali Rezaee, Mohsen Moohebati, Seyed Hamed Hashemi Shahri, Susan Darroudi","doi":"10.1186/s13104-025-07203-5","DOIUrl":"https://doi.org/10.1186/s13104-025-07203-5","url":null,"abstract":"<p><strong>Objectives: </strong>Coronary artery disease, caused by atherosclerosis, necessitates assessing plaque formation risk using indices like the atherogenic index of plasma (AIP), Castelli's risk indexes (CRI-I and CRI-II), the atherogenic coefficient (AC), and the triglyceride-total cholesterol-body weight index (TCBI). Although TCBI primarily assesses mortality risk, its relationship with stenosis severity is unclear. Utilizing data from a prior study, a case-control analysis was conducted on 1,187 subjects, which included 781 patients who underwent coronary angiography and 406 healthy controls. The indices were compared across varying degrees of arterial blockages.</p><p><strong>Results: </strong>AIP significantly correlated with stenosis severity in women, increasing the risk of three-vessel stenosis by 2.5 times. AC raised the risk of single-vessel stenosis in men by 2.7 times. CRI-I and CRI-II showed a positive relationship with arterial stenosis in women, with CRI-I increasing the risk of two and three-vessel blockages by 21.9% and 22.4%, respectively. A one-unit increase in CRI-II raised the risk by 33.1% for two arteries and 25.3% for three. In conclusion, AIP, CRI-I, and CRI-II in women, along with AC in men, correlated with arterial stenosis severity, while TCBI did not. Further research is needed to determine which index is most effective in predicting CAD risk.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"180"},"PeriodicalIF":1.6,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12004764/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143977572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Informing research design through patient and public involvement; patients and carers with lived experience post-hospital discharge and potential roles for general practice pharmacists.","authors":"Faiza Yahya, Sam Bartlett, Vibhu Paudyal, Muhammad Abdul Hadi, Hamde Nazar, Ian Maidment","doi":"10.1186/s13104-025-07248-6","DOIUrl":"https://doi.org/10.1186/s13104-025-07248-6","url":null,"abstract":"<p><strong>Background: </strong>Medication safety across care transitions remains a significant burden on healthcare systems. Patient and Public Involvement (PPI) is useful at the very early stages of intervention development to inform research priorities. The aim of this PPI was to scope patients' and carers' lived experiences of medicines management post-hospital discharge to inform the design of a research proposal.</p><p><strong>Methods: </strong>A research planning PPI workshop and additional one-to-one discussions were undertaken with patients and informal carers who had experienced a recent discharge from hospital and were prescribed regular repeat medications.</p><p><strong>Results: </strong>The 12 public contributors identified that the priority for patients was not limited to medication management alone but rather a broader care package. Multiple themes as priorities for research emerged: (1) broader holistic and social aspects of care involving various healthcare professionals, (2) practical aspects such as timeliness of follow-up and co-ordination of medication management, and (3) communication with the patient/carer and information transfer between settings.</p><p><strong>Conclusion: </strong>Valuable insights from this PPI helped inform future research design priorities and identify the need for a more holistic approach to care. Future work with multi-stakeholder engagement involving different professionals across sectors is needed to explore safer integrated transitions of care, as well as the use of ongoing PPI and co-design, considering populations that are most vulnerable.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"181"},"PeriodicalIF":1.6,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12007321/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143975891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Why do patients with ischemic heart disease modify their lifestyle? a qualitative study : Motivations for lifestyle modification after IHD.","authors":"Naser Javadi, Mansour Dianati, Mohsen Taghadosi","doi":"10.1186/s13104-025-07169-4","DOIUrl":"https://doi.org/10.1186/s13104-025-07169-4","url":null,"abstract":"<p><strong>Objective: </strong>Ischemic Heart Disease (IHD) is a major cause of death worldwide, particularly in low- to middle-income nations, such as Iran. Lifestyle modification (LSM) (e.g., healthy nutritional patterns, regular physical activity, smoking cessation, and stress management) can prevent the development of IHD. This study aimed to identify the motivations behind LSM in patients with IHD.</p><p><strong>Results: </strong>This qualitative study employed traditional content analysis and purposive sampling from cardiac rehabilitation (CR) centers in Iran. Data were collected through semi-structured interviews, analyzed using Graneheim and Lundman steps, conducted from October 2023 to September 2024. The participants included 15 IHD patients with LSM experience, one patient's son, and 4 healthcare professionals (nurses, clinical psychologists, cardiologists, and nutritionists). The patients had an average age of 63 years and varied in sex, occupation, education, and marital status. Interviews averaged 69 min, ranging from 50 to 100 min. The analysis revealed a theme of \"seeking wise survival,\" with 10 subcategories and three categories: interest and fear (e.g., family interest, fear of death), comprehensive recommendations, and individual and social benefits (e.g., time and cost savings). The findings of this study provide scientific evidence for HCPs to encourage and educate patients and their families regarding the LSM.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"182"},"PeriodicalIF":1.6,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12007254/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143970756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding the factors behind non-adherence to pesticide safety guidelines among smallholder farmers in Fogera and MEcha districts, northwestern Ethiopia.","authors":"Geteneh Mitku Chekol","doi":"10.1186/s13104-025-07217-z","DOIUrl":"https://doi.org/10.1186/s13104-025-07217-z","url":null,"abstract":"<p><strong>Objective: </strong>The objective of the research was to identify key factors influencing smallholder farmers' why not follow the recommended pesticide safety practices in northwestern Ethiopia. The study conducted in 2020/2021 investigated factors influencing smallholder farmers' adherence to recommended pesticide safety practices in northwestern Ethiopia. The survey involving 50 farmers in Fogera and 53 in Mecha assessed pesticide use practices and perceptions, aiming to reveal common challenges in pesticide management. Survey data highlighted significant pesticide application and barriers related to adopting personal protective equipment (PPE), proper pesticide storage, integrated pest management (IPM), and safe disposal of containers.</p><p><strong>Result: </strong>Statistical analyses indicated non-significant differences between districts regarding these practices, underscoring universal issues such as economic constraints, limited resource access, and inadequate awareness. Crops like maize, faba bean, and cabbage showed high pesticide usage rates in both districts without statistically significant differences, emphasizing their cumulative impact on food safety. This finding underscores the urgent need for comprehensive interventions. Measures such as subsidized PPE, infrastructure development for safe pesticide storage, enhanced educational campaigns, and strengthened regulatory frameworks are crucial to promote sustainable agricultural practices and mitigate health and environmental risks. In conclusion, the study identifies widespread barriers to effective pesticide management among smallholder farmers in Fogera and Mecha, including economic limitations and resource constraints. Addressing these challenges necessitates a multifaceted strategy that includes subsidized PPE, improved storage infrastructure, and intensified educational initiatives to foster sustainable practices and safeguard both human health and the environment.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"177"},"PeriodicalIF":1.6,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12004810/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the association between demographic factors and patient satisfaction with recovery in the early phase after non-catastrophic musculoskeletal injuries: a cross-sectional study.","authors":"Mahshad Maleki, Shirin Modarresi","doi":"10.1186/s13104-025-07210-6","DOIUrl":"https://doi.org/10.1186/s13104-025-07210-6","url":null,"abstract":"<p><strong>Background: </strong>Orthopedic injuries can negatively impact both the physical and mental health of patients. Ensuring patient satisfaction with their recovery is crucial for meeting patient-centered goals and enhancing overall health outcomes.</p><p><strong>Objective: </strong>We aimed to investigate whether satisfaction with recovery can be predicted based on demographic information and baseline characteristics in people with non-catastrophic musculoskeletal trauma.</p><p><strong>Methods: </strong>Participants with acute musculoskeletal injuries were recruited. The Satisfaction and Recovery Index (SRI) was used to assess the patient's satisfaction with their recovery. A multivariable linear regression model was created to determine factors that are associated with SRI scores.</p><p><strong>Results: </strong>A total of 100 patients participated, with a mean age of 32 years and 82% male. The majority had a high school education or lower, were employed, and sustained left-side injuries. Injuries were most often fractures/dislocations caused by motor vehicle collisions. The results of the multivariable linear regression analysis indicated no significant factors predicting satisfaction with recovery.</p><p><strong>Conclusions: </strong>The studied demographic variables and baseline characteristics are not associated with the level of satisfaction with recovery among patients with non-catastrophic musculoskeletal trauma. Clinicians can use these findings to rule out these variables as contributors to low (or high) satisfaction with recovery. Future studies must assess the contribution of other probable and relevant psychological and social characteristics.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"175"},"PeriodicalIF":1.6,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12001588/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143963630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The medical radiation technologist model: a streamlined process for procedural sedations.","authors":"Jennifer Meher, Julien Meyer, Annette Tracey, Housne Begum, Pria Nippak","doi":"10.1186/s13104-025-07242-y","DOIUrl":"https://doi.org/10.1186/s13104-025-07242-y","url":null,"abstract":"<p><strong>Objective: </strong>Procedural sedations are a growing and routine form of sedation. Some of them may not require the presence of a nurse. The purpose of this study is to assess the impact of the Medical Radiation Technologists (MRT) model, which forgo the presence of a Registered Nurse (RN), for procedural sedations in Computed Tomography biopsies. The setting was a teaching hospital that moved from an RN to an MRT model. We compared staff utilization, turnaround times and incident reports between pre and post implementation, over 19 months overall.</p><p><strong>Results: </strong>No adverse events were observed under either model. Wait times were reduced by 25% from 131 to 98 min. Turnaround times were reduced by 2 min from 52 to 50 min. The joint cost of RN/MRIT was reduced by 37% per procedure, from $141 to $88.</p><p><strong>Conclusion: </strong>These results suggest that the MRT model is more cost-effective without compromising quality of care. The MRT model is promising and should be extended to more facilities and other routine procedural sedations to save time and resources.</p>","PeriodicalId":9234,"journal":{"name":"BMC Research Notes","volume":"18 1","pages":"176"},"PeriodicalIF":1.6,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12001414/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143989018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}