CD4 cell count and viral load count association and its joint risk factors among adult TB/HIV co-infected patients: a retrospective follow-up study.

Abstract

Objective: The aim of this study was to determine CD4 cell count and viral load count association and its joint clinical risk factors among adult TB/HIV co-infected patients. The purpose of this research was leads to contribute improved planning and execution of screening programs, regular follow-ups, and prevention measures.

Result: The baseline variability for viral load ([Formula: see text]) was higher than CD4 cell (819.797). Furthermore, the correlation matrix (R) shows that the baseline subject-specific CD4 cell and viral load were negatively correlated (- 0.[Formula: see text]). There was also a negative relationship between the subject-specific change CD4 cell and baseline viral load (-[Formula: see text]), subject-specific baseline CD4 cell, and the patient-specific change of viral load (-0.6513), longitudinal trajectory (association of evolution) for the two random slopes [Formula: see text]-0.9413). Then, there was very strong negative relationship between subject-specific change CD4 cell and viral load over time. Visit time[Formula: see text], white blood cell[Formula: see text], good[Formula: see text] and fair[Formula: see text]) adherence, hemoglobin ≥ 11 g/dl[Formula: see text], baseline CD4 cell ≥ 200 cells/mm³[Formula: see text], and baseline viral load < 10,000 copies/mL[Formula: see text]hematocrit[Formula: see text]and monocytes of patients[Formula: see text] were a joint determinates for viral load and CD4 cell, respectively.