BMC Women's Health最新文献

{"title":"A case report of breast abscess caused by Peptoniphilus harei after endoscopic breast-conserving surgery and radiotherapy for breast cancer and literature review.","authors":"Siqi He, Zheng Wang, Xiaoling Liu, Wei Wei, Guangxin Li","doi":"10.1186/s12905-025-03915-9","DOIUrl":"10.1186/s12905-025-03915-9","url":null,"abstract":"<p><strong>Background: </strong>Breast abscess is a common infectious disease of the breast, but breast abscess caused solely by Peptoniphilus harei is extremely rare. Endoscopic breast-conserving surgery for breast cancer is an emerging breast surgical technique that is considered a clean procedure with a low postoperative infection rate.</p><p><strong>Case presentation: </strong>We report a case of a patient who underwent endoscopic breast-conserving surgery for breast cancer and developed a breast abscess in the surgical area after radiotherapy. Bacterial culture and identification confirmed that the abscess was caused by Peptoniphilus harei infection. After treatment with antibiotics targeting Peptoniphilus harei and active wound debridement, the patient achieved complete recovery.</p><p><strong>Conclusions: </strong>This is the first reported case of breast abscess caused solely by Peptoniphilus harei after endoscopic breast-conserving surgery and radiotherapy for breast cancer. Early identification of the pathogen and targeted treatment are essential for successful management.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"419"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12400720/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Promoting early detection of necrotizing soft tissue infection of the upper extremity in patients with history of breast cancer: a case report.","authors":"Medha Reddy, Manuel Goicoechea, Marc K Wallack","doi":"10.1186/s12905-025-03932-8","DOIUrl":"https://doi.org/10.1186/s12905-025-03932-8","url":null,"abstract":"<p><strong>Background: </strong>Lymphedema is estimated to affect one in three breast cancer survivors longitudinally. Despite the high prevalence of secondary lymphedema amongst breast cancer survivors, it remains unrecognized and underdiagnosed by patients and physicians alike.</p><p><strong>Case presentation: </strong>A 56-year-old female with a three-year history of remission of breast cancer, status post bilateral total mastectomy with right axillary node dissection complicated by a seroma of the right chest wall and adjuvant chemotherapy and radiation, presented with a one-week history of worsening right upper extremity erythema, edema, and tenderness. She denied any known trauma, needle insertions, or insect bites. On initial examination, she was afebrile, hypotensive (90/60 mmHg) with an erythematous, edematous right bicep that was tender and fluctuant to palpation. Distal pulses, strength, and sensation were at baseline bilaterally. CT and ultrasound imaging showed extensive subcutaneous edema and skin thickening of the right arm, compatible with cellulitis. The patient was diagnosed with a necrotizing soft tissue infection of the right upper extremity and treated with antibiotic therapy, incision and drainage, controlled surgical debridement, and eventual synthetic dermal grafting.</p><p><strong>Conclusions: </strong>In necrotizing soft tissue infection in the context of lymphedema, we highlight the need for patient and physician education regarding secondary lymphedema in breast cancer survivors to promote early detection and intervention-a critical first step to prevention of superimposed infectious etiologies.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"417"},"PeriodicalIF":2.7,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12398006/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors associated with female genital mutilation/cutting in Tanzania: insights from Tanzania demographic and health survey 2022.","authors":"Tumaini Nyamhanga, Oliva Kapinga, Brian A Muro, Pankras Luoga","doi":"10.1186/s12905-025-03965-z","DOIUrl":"https://doi.org/10.1186/s12905-025-03965-z","url":null,"abstract":"<p><strong>Background: </strong>Globally, female genital mutilation (FGM) remains a significant public health concern. The practice is disproportionately high in African countries. In Tanzania, FGM poses serious health risks to both women, girls and children. However, there is limited empirical literature on the factors associated with FGM in Tanzania. This study intended to fill the gap.</p><p><strong>Methods: </strong>In this study, we analysed secondary data from a cross-sectional survey, involving a weighted sample of 7,678 women aged 15-49 from the 2022 Tanzania Demographic and Health Survey (TDHS). In this study, the binary dependent variable indicates whether the respondent is mutilated or not mutilated while the independent variables include various demographic characteristics of women, such as age, education level, socioeconomic status, and region of residence. Bivariate and multivariable logistic regression analyses were conducted. A threshold of p-value < 0.05 at 95% Confidence Interval (CI) was used to determine a statistically significant association.</p><p><strong>Results: </strong>The prevalence of FGM in Tanzania is 8.2% and types I and II (a cut with or without removal of flesh) were the dominant types of FGM practice by 89.2%. After controlling for other variables, higher odds of being mutilated was reported in; older ages 45-49 years (adjusted Odds Ratio(aOR));3.09, 95%CI: 1.72, 5.54), in rural areas (aOR;2.30, 95%CI:1.4,3.6), in women in unions (aOR;1.60, 95%CI:1.20,2.10), in Northern zone (aOR;9.10, 95%CI: 4.60, 17.80), those who ever heard about FGM had 2.27 times (aOR; 2.27, 95%CI: 0.82, 6.29), those who said FGM required by religion had 8.3 times (aOR; 8.30, 95%CI: 4.30,16.03), those who supported FGM had 5.29 times (aOR; 5.29, 95%CI: 2.69, 10.40) higher odds of reporting having undergone FGM compared to those who said the practice should be stopped. Conversely, lower odds of experiencing FGM was reported in; women with at least secondary education (aOR;0.40, 95%CI:0.20,0.60), those from richest households (aOR;0.40, 95%CI: 0.20, 0.60) and those who said distance to a health facility was not a big problem (aOR;0.70, 95%CI: 0.50, 0.90).</p><p><strong>Conclusion: </strong>Our study found that prevalence of FGM in Tanzania is 8.2%. The factors associated with experiencing FGM included woman's socio-demographic factors like older age, rural residency, lower or no education, poorest wealth quintile, supporting FGM to continue and being in unions. This calls for collaborative efforts between the government and other stakeholders to design targeted interventions as ending FGM require a multisectoral approach addressing aforementioned determinants across multiple levels including education and wealth creation programs particularly to uneducated and poorest women from rural areas.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"415"},"PeriodicalIF":2.7,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12398043/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A survey assessing the impact of symptoms related to the menstrual cycle and perceptions of workplace productivity: considerations for employer-sponsored menstrual health programs.","authors":"Danielle M Raves, Wynetta D Herrera, Matthew E Darnell, Tristan Rice, Craig Friedman, Stephanie C Moratti, Stacy T Sims, Wandasun B Sihanath, Shannon N Ehrhardt, Amanda Phillips","doi":"10.1186/s12905-025-03833-w","DOIUrl":"https://doi.org/10.1186/s12905-025-03833-w","url":null,"abstract":"<p><strong>Background: </strong>Hormonal-related symptoms experienced during natural or contraceptive-driven menstrual cycles have implications on work-related productivity; however, employer-sponsored menstrual health resources are widely unavailable. Actionable research-based evidence is needed to develop menstrual health programs that proactively help working females mitigate their hormonal-related symptoms and optimize their hormone profiles and work-related performance. This study sought to evaluate the prevalence and severity of hormonal-related symptoms and assess the directional impact of hormonal-related symptoms on work-related productivity across cyclical hormone phases.</p><p><strong>Methods: </strong>A cross-sectional, descriptive questionnaire was used to measure hormonal-related symptoms and work-related productivity in 372 working females of reproductive age in the United States. The validated Menstrual Distress Questionnaire was used to measure the prevalence and severity of hormonal-related symptoms. The Menstrual Cycle-Related Work Productivity Questionnaire was modified and used to assess perceptions of work-related productivity measures across all cyclical hormone phases. Cumulative link mixed models and Bayesian adjacent category models were employed to determine the relationship between hormonal-related symptoms and work-related productivity, independent of age, body mass index (BMI), heavy bleeding experience, cyclical hormone phase, contraceptive use, Exos employment status and other hormonal-related symptoms.</p><p><strong>Results: </strong>Hormonal-related symptoms were present across cyclical hormone phases, and the most severe disturbances were experienced during the bleed-phase. Distributions of perceived work productivity were significantly more negative during the pre-bleed and bleed phases and more positive during the late follicular and early luteal phases. Self-reported hormonal-related symptoms were significantly associated with perceptions of work-related productivity, independent of potential confounders.</p><p><strong>Conclusions: </strong>Cyclical hormone fluctuations impact perceived work-related productivity variably by phase. Self-reported hormonal-related symptoms are associated with perceptions of work-related productivity. Our findings identify important considerations for the development of menstrual health programming to optimize the lived experience of female physiology in the workplace.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"418"},"PeriodicalIF":2.7,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12398178/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144942859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breast cancer and microbiome: a systematic review highlighting challenges for clinical translation.","authors":"Chandrani Bose, Natalia Gontarczyk Uczkowski, Krishna Sukla, Nilixa Raval, Mohammed Monzoorul Haque, Yingting Zhang, Binuja Varma, Jaya M Satagopan","doi":"10.1186/s12905-025-03843-8","DOIUrl":"https://doi.org/10.1186/s12905-025-03843-8","url":null,"abstract":"<p><strong>Purpose: </strong>Breast cancer, the most common cancer in women worldwide, is linked to microbiome imbalances. This suggests the potential for microbiome-based breast cancer management. However, a comprehensive and reproducible understanding of the microbiome's role in breast cancer is lacking. We conducted a systematic literature review to explore microbiome signatures and specific genera associated with breast cancer development, subtypes, and outcomes.</p><p><strong>Methods: </strong>We searched PubMed, Embase, Scopus, and Web of Science using the terms \"microbiome\" and \"breast cancer\", limiting to publications of human studies in English language between January 2011 and January 2025, and adhering to the Preferred Reporting Items for Systematic Reviews and Meta Analyses (PRISMA) guidelines. We extracted the study characteristics and results and summarized our findings.</p><p><strong>Results: </strong>From 2536 articles, we identified 48 eligible studies - 22 case-control, 13 cohorts without any intervention, and 13 cohorts with an intervention. These studies included 3735 women with and 2023 without a diagnosis of breast cancer. Most studies used fecal (29) or breast tissue (14) samples. The genera Clostridium, Lcatobacillus, Prevotella were most commonly associated with breast cancer. However, no genus was consistently linked to the same outcome across studies, rendering meta-analysis unfeasible. Overall, we observed heterogenous methods for data generation and computational analysis leading to challenges in comparative analysis.</p><p><strong>Conclusions: </strong>While several genera are linked to breast cancer, the findings lack consistency across studies. Future studies should employ standardized outcomes, data collection, and processing methods to establish reproducible microbial markers to develop effective microbiome-based breast cancer management strategies.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"416"},"PeriodicalIF":2.7,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12398099/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Human papillomavirus infection among patients with cervical cancer in Cambodia.","authors":"Jacob E Gardner, Kyle Jung, Michel Pluot, Tracy Sherertz, Andrew Berchuck, Rath Beauta, Huy Chankong, Yi Ratana, Sarameth Thou, Aun Korn, Phok Ratana, Sanine Lay, Pheng Meth, Sokchann Khan, Kalyan Meng, Chhorvathany Ay, Karuna Garg, Jae Jung","doi":"10.1186/s12905-025-03954-2","DOIUrl":"https://doi.org/10.1186/s12905-025-03954-2","url":null,"abstract":"<p><strong>Background: </strong>Cervical cancer is the second-most common cancer among Cambodian women, with an estimated 1274 new cases and 670 deaths annually. On October 5, 2023, the Cambodian government introduced HPV vaccination for 9-year-old girls into the country's national immunization schedule. The optimal strategy for this nascent vaccination campaign, and the expected effects thereof, depend on a robust understanding of HPV epidemiology in Cambodia. To this end, we conducted a retrospective, observational, cross-sectional study of HPV infection among patients with cervical cancer at Calmette Hospital in Phnom Penh, Cambodia.</p><p><strong>Methods: </strong>Fifty specimens of formalin-fixed, paraffin-embedded cervical tumor tissue selected from archival specimens of biopsies performed at Calmette Hospital between April 2019 to March 2020 were analyzed using next-generation sequencing to detect HPV types present in each sample. Forty-seven samples of non-cancerous cervical tissue were selected for comparison from archival specimens of non-oncological hysterectomies performed at Cambodia's National Maternal and Child Health Center between January 2020 to March 2021 and analyzed using PCR, gel electrophoresis, and p16 immunohistochemistry to detect the presence of HPV infection in each sample. Those that tested positive for HPV underwent next generation sequencing to detect which HPV subtypes were present in each sample.</p><p><strong>Results: </strong>HPV-16/18 were detected in 83.3% of cervical cancer specimens, and HPV-58 was detected in 11.9%. Multiple HPV subtypes were detected in 2.4% of cancer specimens. Neither HPV-16 nor - 18 differed statistically in observed prevalence from either those rates reported for all Asia or globally. The observed prevalence of HPV-58 was not dissimilar between Cambodia and Asia, however Cambodia's prevalence of HPV-58 was substantially higher than the global rate. HPV DNA was detected in 0/47 control specimens.</p><p><strong>Conclusion: </strong>This is the first study of HPV type prevalences among patients with cervical cancer in Cambodia, providing epidemiological data that is crucial for assessing and optimizing the country's vaccination policy. Results suggest that the efficacy of current vaccination strategy should not be hindered by any outsized prevalence of non-vaccine type HPV.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"413"},"PeriodicalIF":2.7,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12395727/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, Attitude, and Practice of Polycystic Ovarian Syndrome Diagnosis among Health Care Providers in Addis Ababa, Ethiopia.","authors":"Ephrata W Erku, Mariamawit M Yanni, Hikma M Mohamed, Saba F Weldehawaria, Elham M Asfaw, Melatwork Tibebu, Abay Sisay, Mikias Negash","doi":"10.1186/s12905-025-03948-0","DOIUrl":"https://doi.org/10.1186/s12905-025-03948-0","url":null,"abstract":"<p><strong>Background: </strong>Polycystic Ovary Syndrome (PCOS) is an endocrine disorder affecting women of reproductive age, characterized by hormonal imbalances, reproductive abnormalities, and metabolic disturbances. The diagnosis and management of PCOS is not well documented, particularly in the Ethiopian healthcare setup.</p><p><strong>Methods: </strong>A cross-sectional study was conducted on 210 healthcare professionals selected from hospitals in Addis Ababa from April 10 to May 24, 2024. Data was collected using a standardized questionnaire and double entered using Microsoft Excel and analyzed by using the Statistical Package for Social Sciences (SPSS) Version 25. Likert scale was used for the attitude analysis and the average score measure of difference was used for knowledge, attitude and practice (KAP) level of measurements. ANOVA was used for testing the association of p-value less than 0.05% and Spearman's rho was used to test correlation.</p><p><strong>Result: </strong>Out of 210 respondents, only 43 (20.5%) had \"Good Knowledge\" about PCOS and its diagnosis. Gynecologists exhibited the highest knowledge (58.3%) and practice (50%) scores compared to other professions. A majority, 187 individuals (89.0%), were classified as having a \"Good Attitude\" towards PCOS and its diagnosis. Only 42 (22.0%) of participants indicated Good Practice. Among the hormonal markers, Follicle Stimulating Hormone (FSH) on its own was the most frequently used (75 participants, 41.4%), Anti-Müllerian hormone (AMH) and Dehydroepiandrosterone Sulfate (DHEAS) were only utilized by 15.5% (28) and 17.7% (32) of participants respectively.</p><p><strong>Conclusion: </strong>The study highlighted significant gaps in knowledge, attitude, and practices among healthcare professionals in Ethiopia regarding PCOS diagnosis. Inadequate practices were common, with reliance on ultrasonography and physical symptoms alone. More attention should be given to creating proper diagnosis and referring channels along with teaching and advocacy in academia and the public to promote women's reproductive health.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"414"},"PeriodicalIF":2.7,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12395725/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Negative experiences of breastfeeding beyond the infancy age of one year in public - a deductive content analysis of a cross-sectional global sample.","authors":"Jessica Jackson, Jenny Hallam, Reza Safari","doi":"10.1186/s12905-025-03704-4","DOIUrl":"https://doi.org/10.1186/s12905-025-03704-4","url":null,"abstract":"<p><strong>Background: </strong>The global recommendations of continuing breastfeeding for two years and beyond are not being realised. Barriers to breastfeeding beyond the infancy age of one year continue to be seen globally despite the recognition that facilitating it could prevent 823,000 child and 98,000 parent deaths every year. The visibility of breastfeeding in public, particularly for those who continue to breastfeed, is thought to be reducing and this in turn impacts public acceptability. However, research exploring women's experiences breastfeeding in public typically focuses on newborns. Therefore, this study explores negative experiences of continuing breastfeeding, between the ages of 1 to < 2 years, in a global sample of participants.</p><p><strong>Methods: </strong>A cross-sectional design via an online self-completed questionnaire was adopted to collect data from women, at one point in time, who had experience of breastfeeding a child between the ages of 1-2 years. Participants who had experienced a negative response were asked to share their experiences in a free text question. A content analysis was adopted to explore the information conveyed by the participants through the conceptualising of condensed broad category descriptions.</p><p><strong>Results: </strong>There were 2,562 women who had a negative experience of breastfeeding in public places, 1,674 from five continents (Europe 994, America 948, Asia 51, Australia 161, Africa 20, Unknown 12) shared their experience. The findings present four categories: Unsolicited Opinion (56%), Judgemental (39%), Indecent Act (16%) and, Prohibited (7%). Commonly there were experiences of unwanted advice or being shamed and stigmatised to undermine breastfeeding practice. More zealous public reactions, such as implying child abuse, sexualising breastfeeding, or expressing shock and disgust were less common. The least likely to occur were experiences of being told to refrain from, move away or cover up.</p><p><strong>Conclusions: </strong>The findings reaffirmed that there is a wider social stigma experienced by women breastfeeding beyond infancy in public. This highlights that women who continue to breastfeed are being shamed and blamed for their breastfeeding choices. More efforts are needed to address social and cultural challenges, with an increase in wider knowledge to support breastfeeding beyond infancy.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"412"},"PeriodicalIF":2.7,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12395642/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early menopause as an independent risk factor for postoperative atrial fibrillation in women undergoing coronary artery bypass grafting: a retrospective cohort study.","authors":"Haokai Qin, Jiyuan Luo, Yunxiao Yang, Xunxun Feng, Xiubin Yang, Kun Hua, Mingyang Zhou","doi":"10.1186/s12905-025-03941-7","DOIUrl":"https://doi.org/10.1186/s12905-025-03941-7","url":null,"abstract":"<p><strong>Background: </strong>Early menopause is considered directly related to the occurrence of isolated atrial fibrillation. In this study, we aim to explore the relationship between early menopause and the incidence of postoperative atrial fibrillation (POAF) occurring following coronary artery bypass grafting (CABG).</p><p><strong>Method: </strong>This retrospective cohort study included patients who underwent CABG at Beijing Anzhen Hospital from January 2020 to December 2023. Patients were divided into two cohorts: early menopausal individuals (age < 45) and non-early menopausal individuals (age ≥ 45). Baseline characteristic disparities were adjusted via including all baseline variables with an standardized mean difference (SMD) > 0.1 as covariates in the inverse probability of treatment weighting (IPTW) analysis. The correlation between menopausal age and the occurrence of POAF was analyzed utilizing logistic regression and restricted cubic spline (RCS).</p><p><strong>Results: </strong>Among the 1825 female patients who underwent CABG in this study, 537 developed POAF. After IPTW analysis to control for baseline variables, it was found that the incidence of POAF in the early menopause group was significantly higher than in the non-early menopause group (42.1% vs. 28.2%). Logistic regression analysis showed that early menopause was associated with an increased risk of POAF (adjusted OR: 1.76, 95% CI: 1.30-2.38, p < 0.001). RCS analysis also confirmed our hypothesis, showing that early menopause is associated with an increased risk of POAF.</p><p><strong>Conclusion: </strong>Female CABG patients with early menopause have a higher incidence of POAF compared to those without early menopause. Additionally, the younger the age at menopause, the higher the risk of developing POAF. These findings suggest that menopausal age should be considered in preoperative risk stratification, and early menopausal women may benefit from targeted monitoring or preventive strategies to reduce POAF risk.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"411"},"PeriodicalIF":2.7,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12392493/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Indigenous women's experiences, symptomology and understandings of menopause: a scoping review.","authors":"Manisha Gore, Julia Morgan","doi":"10.1186/s12905-025-03953-3","DOIUrl":"10.1186/s12905-025-03953-3","url":null,"abstract":"<p><strong>Background: </strong>Most women at some time in their life will experience menopause. Recent commentaries, however, have highlighted that menopause is a neglected area of both research and health- related support; this being especially the case for ethnic minorities and Indigenous women. Coupled with the World Health Organization's Global Plan of Action on Indigenous Health, which calls for global attention to the health of Indigenous Peoples, this makes it timely to undertake a scoping review of the literature on Indigenous women's experiences and understandings of menopause to identify themes and gaps across the contemporary literature.</p><p><strong>Methods: </strong>Arksey and O'Malley's scoping review framework and PRISMA-ScR guidelines were utilised. A comprehensive search of eight electronic databases as well as grey literature from 2015 to 2025 identified 319 articles. After removing duplicates and applying inclusion criteria and exclusion criteria, 21 articles were included in the final review.</p><p><strong>Results: </strong>Eleven of the studies were from India, three from United States of America, two from Canada and one study from each of the following countries: Aotearoa/New Zealand, Argentina, China, Colombia and Malaysia. Sixteen studies were quantitative and focused primarily on symptomology, age of menopause and impacts on health. Minimal qualitative research was evident. Themes included 1) menopause symptomology; 2) menopause and metabolic health; 3) age of menopause and associations with factors such as age of first menarche, age of marriage, nulliparity, and occupation; 4) menopause knowledge, which was limited for some Indigenous women, contributing to fear and anxiety; 5) symbolic and cultural meanings, which underpinned Indigenous women's understandings of menopause; 6) challenges in accessing person-centred and culturally sensitive healthcare and menopause support.</p><p><strong>Conclusions: </strong>The research question for this scoping review focused on exploring the global academic literature on Indigenous women's experiences, symptomology, and understandings of menopause. Culturally sensitive health education, improved healthcare access and more research which explores Indigenous worldviews and their impact on how menopause is understood and experienced are needed to support Indigenous women through menopause.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"408"},"PeriodicalIF":2.7,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12379502/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}