BMC Women's Health最新文献

{"title":"Perception of university students about the use of painkillers, other remedies and lifestyle modifications for primary dysmenorrhea; a cross-sectional study at KEMU.","authors":"Amina Tahir, Bisal Naseer, Fizza Shafaq","doi":"10.1186/s12905-025-03777-1","DOIUrl":"10.1186/s12905-025-03777-1","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>Dysmenorrhea is a common gynecological complaint, affecting a significant percentage of menstruating women. The mainstay for the treatment of dysmenorrhea is NSAIDs and hormonal contraceptives while complementary and alternative therapies (CATs) are adjunct to it. This study investigates the perception of female medical students with dysmenorrhea towards the use of painkillers and CATs.</p><p><strong>Methods: </strong>We conducted this cross-sectional study among female medical students of Lahore by circulating the Google Forms-based questionnaire. Correlation analysis and logistic regression were applied using SPSS and descriptive statistics were given in frequencies and percentages.</p><p><strong>Results: </strong>Out of 202 participants, 76.7%(n = 155) experienced dysmenorrhea. 46%(n = 93) of the respondents reported using painkillers; paracetamol being the most common. 68.8% (n = 139) used CATs; bed rest and hot compresses were most used. The most common reason for using painkillers was their effectiveness (61.6%), followed by availability (42.5%). For CATs, the reason of choice included to reduce the need for analgesic (58%) and safety (38.3%). About 40.1% of respondents believed CATs were less effective than painkillers. 84.1% agreed that long-term consumption of painkillers causes stomach ulcers or kidney damage. The factors that led to CATs not being preferred over painkillers included less information about them (33.7%), time-consuming (25.7%), and the concept of non-effectiveness (20.3%). Uni-variate logistic regression analysis showed that students with severe dysmenorrhea had higher odds of using painkillers as compared to the students who had mild dysmenorrhea. (OR: 6.319, 95% CI: 3.244-12.309, P = 0.000).</p><p><strong>Conclusions: </strong>The prevalence of the use of CATs is high among female students as compared to painkillers and hormonal contraceptives (first-line). The reason for choosing CATs included reducing the need for analgesics, safety, and availability. Females should be encouraged to use the first-line therapies after consultation with doctors; for the effective management of dysmenorrhea and improvement of their quality of life.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"234"},"PeriodicalIF":2.4,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12087242/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144101370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insufficient knowledge of Human Papillomavirus among reproductive-aged women from Arak, Iran.","authors":"Parnia-Sadat Fathi, Masoomeh Sofian, Amir Almasi-Hashiani, Mona Sadat Larijani, Fatemeh Ashrafian, Amitis Ramezani","doi":"10.1186/s12905-025-03765-5","DOIUrl":"10.1186/s12905-025-03765-5","url":null,"abstract":"<p><strong>Background: </strong>The Human Papillomavirus (HPV) is the most common sexually transmitted infection worldwide. Knowledge about this virus and its vaccine is still limited among women in developing countries. Therefore, this study aimed at evaluation of women's knowledge about HPV and vaccination to identify the related factors conducting on reproductive-aged women referred to health care centers in Arak, Iran.</p><p><strong>Methods: </strong>In this cross-sectional study, a researcher-made questionnaire was applied to assess the participants' knowledge about HPV and its vaccination among Iranian reproductive-aged women. Mann Whitney U test, and Kruskal Wallis test were used to analyze the data. Quantile regression was employed to account for potential confounding factors.</p><p><strong>Results: </strong>Totally, 400 women with a mean age of 32.5 years were investigated. The vast majority of the participants (82%) were married, 32.2% graduated from high school, 64.0% had 1-2 children, 93% lived in the urban area. The associated HPV and vaccine knowledge was evaluated to be \"insufficient\" in 86.5% and 79% of the participants, respectively. Out of 400, 37.5% and 34.5% of participants were aware of HPV vaccine protection against cervical cancer and genital warts, respectively. Multifactorial quantile regression models revealed that women with higher levels of education demonstrated significantly greater awareness of HPV. Additionally, employed women and those with higher education exhibited notably increased awareness of the HPV vaccine.</p><p><strong>Conclusions: </strong>The level of understanding in terms of the incidence and prevention was evaluated \"insufficient\" in our study. The findings highlight the importance of further campaigns to improve the awareness of HPV among Iranian women. Vaccination programs should be seriously considered to prevent HPV infection and its complications like cervical cancer.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"238"},"PeriodicalIF":2.4,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12087100/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144101367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and factors associated with intimate partner violence among women in Tanzania: evidence from Tanzanian demographic and health survey 2022.","authors":"Pankras Luoga, Siri A Abihudi, Jovinary Adam, Magreth Thadei Mwakilasa","doi":"10.1186/s12905-025-03760-w","DOIUrl":"10.1186/s12905-025-03760-w","url":null,"abstract":"<p><strong>Background: </strong>Intimate partner violence (IPV) remains a pervasive issue in Tanzania, impacting the physical, mental, and emotional well-being of women across the country. Despite the existence of legal frameworks aimed at protecting women's rights, IPV persists in Tanzania. Understanding the magnitude and factors associated with IPV among women provides valuable insights that can be used to shape policies and interventions targeted at preventing and addressing IPV in the country. However, there is a paucity of evidence on the prevalence and factors associated with IPV nationwide. Therefore, this study is timely for addressing this gap in Tanzania.</p><p><strong>Methods: </strong>The study used a nationally representative secondary data that employed a cross-sectional design. Data for the current study were extracted from the 2022 Tanzania Demographic and Health Survey for women aged 15-49 years. A weighted sample of 4503 ever married or ever partnered women aged 15-49 years was used. The outcome variable was IPV status categorized into binary responses yes/no, while independent variables were socio-demographic and health related characteristics. Data were analysed using descriptive analysis, bivariable and multivariable logistic regression models. A threshold of p-value < 0.05 was used to determine statistically significant factor. The strength of the association was assessed using the adjusted odds ratio (aOR) along with its corresponding 95% confidence interval (CI).</p><p><strong>Results: </strong>The overall prevalence of IPV among women of reproductive age 15-49 years in Tanzania was 38.9%. The multivariable logistic regression results revealed that women who are working (aOR = 1.4,95%CI:1.2,1.7) and those whose husband/partner drinks alcohol (aOR = 2.9,95%CI: 2.4, 3.5) had higher odds of experiencing IPV compared to their counterparts. Conversely, protective factors include women's secondary and higher education level (aOR = 0.7,95%CI:0.5,0.9) and residing in the Southern zones (aOR = 0.4,95%CI:1.5,3.9).</p><p><strong>Conclusion: </strong>The prevalence of IPV among women in Tanzania remains high compared to the global average of 30%. This was mostly associated with women's employment status, and women married/cohabiting with alcohol consumers. The government should implement community-based educational programs to raise awareness about IPV and dedicate more efforts like raising the tax on all alcoholic beverages to controlling alcohol consumption among men as a strategy to combat IPV in society.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"235"},"PeriodicalIF":2.4,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12087117/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144101372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metabolism-associated marker gene-based predictive model for prognosis, targeted therapy, and immune landscape in ovarian cancer: an integrative analysis of single-cell and bulk RNA sequencing with spatial transcriptomics.","authors":"Lele Ling, Bingrong Li, Boliang Ke, Yinjie Hu, Kaiyong Zhang, Siwen Li, Te Liu, Peng Liu, Bimeng Zhang","doi":"10.1186/s12905-025-03750-y","DOIUrl":"10.1186/s12905-025-03750-y","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Ovarian cancer (OC) is a formidable gynecological tumor marked with the highest mortality rate. The lack of effective biomarkers and treatment drugs places a substantial proportion of patients with OC at significant risk of mortality, primarily due to metastasis. Glycolysis metabolism, lipid metabolism, choline metabolism, and sphingolipid metabolism are closely intertwined with the occurrence and progression of OC. Thus, it is of utmost significance to identify potent prognostic biomarkers and delve into the exploration of novel therapeutic drugs and targets, in pursuit of advancing the treatment of OC.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Single-cell RNA sequencing (scRNA-seq) data related to OC were analyzed using AUCell scores to identify subpopulations at the single-cell level. The \"AddModuleScore\" function of the \"Seurat\" package was adopted to score and select marker genes from four gene sets: glycolysis metabolism, lipid metabolism, choline metabolism, and sphingolipid metabolism. A prognostic model for metabolism-related genes (MRGs) was constructed and validated using OC-related marker genes selected from bulk RNAseq data. The MRG-based prognostic model was further utilized for functional analysis of the model gene set, pan-cancer analysis of genomic variations, spatial transcriptomics analysis, as well as GO and KEGG enrichment analysis. CIBERSORT and ESTIMATE algorithms were utilized for assessing the immune microenvironment of TCGA-ovarian serous cystadenocarcinoma (OV) samples. Furthermore, the Tracking Tumor Immunophenotype (TIP) database was employed to examine the anti-cancer immune response in patients with OC. To gain a more in-depth understanding of the process, the frequency of somatic mutations and different types of mutated genes were visualized through the somatic mutation profile of the TCGA database. Moreover, the benefits of immune checkpoint inhibitor (ICI) therapy in individuals with OC were predicted in the TIDE database. In addition, the CMap database was used to predict small-molecule drugs for the treatment of OC. Furthermore, immunohistochemistry, RT-qPCR, CCK-8, Transwell assay, and in vivo tumor xenograft experiments were conducted to validate the prognostic ability of the MRG Triggering Receptor Expressed on Myeloid Cells-1 (TREM1) in OC.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Monocytes were selected using AUCell scoring, and two subpopulations of monocytes, marked by the expression of C1QC&lt;sup&gt;+&lt;/sup&gt; tumor-associated macrophages (TAMs) and FCN1&lt;sup&gt;+&lt;/sup&gt; resident tissue macrophages (RTMs), were identified as marker genes for OC. Subsequently, a prognostic model consisting of 12 MRGs was constructed and validated. Genomic exploration of the prognostic model unveiled an array of biological functions linked with metabolism. Furthermore, copy number variation (CNV), mRNA expression, single nucleotide variation (SNV), and methylation were significantly different across diverse tumors. Analys","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"233"},"PeriodicalIF":2.4,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12084907/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144092820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MCT-modified ketogenic diet as an adjunct to standard treatment regimen could alleviate clinical symptoms in women with endometriosis.","authors":"Fatemeh Naeini, Fatemeh Davari Tanha, Maryam Mahmoudi, Hastimansooreh Ansar, Mohammad Javad Hosseinzadeh-Attar","doi":"10.1186/s12905-025-03798-w","DOIUrl":"10.1186/s12905-025-03798-w","url":null,"abstract":"<p><strong>Background: </strong>Endometriosis as a chronic gynecological condition impairs the quality of life of affected women because it usually accompanied by painful clinical symptoms such as persistent severe acyclic pelvic pain, dyspareunia, and dyschezia. The aim of the present study was to examine the effects of MCT-modified ketogenic diet as an adjunct to standard treatment regimen in women with endometriosis.</p><p><strong>Methods: </strong>This is a 12-weeks randomized controlled clinical trial that was conducted on 50 patients with endometriosis who referred to Yas hospital complex infertility clinic, Tehran, Iran. Participants were randomly allocated to intervention group receiving MCT-modified ketogenic diet plus standard treatment regimen (n = 25) and control group receiving standard treatment regimen (n = 25). Clinical symptoms, anthropometric parameters, lipid profile, and serum aminotransferases were measured at the beginning and end of the study. Statistical analysis was done by SPSS version 27 software and P-value < 0.05 was regarded significant.</p><p><strong>Results: </strong>Finally, 44 patients including 19 subjects in the intervention group and 25 subjects in the control group completed the study. Dyspareunia and dyschezia significantly reduced in the MCT-modified ketogenic diet group compared to the control group at the end of the study (P = 0.02 and P = 0.001, respectively). Also, there was a marginally significant reduction in the final values of pelvic pain (P = 0.07). However, no significant differences in the final value of anthropometric indices including weight, BMI, and WC, serum levels of TG, TC, HDL-C, LDL-C, and aminotransferases including ALT and AST was detected.</p><p><strong>Conclusions: </strong>MCT-modified ketogenic diet as an adjunct to standard treatment regimen could alleviate clinical symptoms including pelvic pain, dyspareunia, and dyschezia in women with endometriosis.</p><p><strong>Trial registration: </strong>Iranian Registry of Clinical Trials IRCT20131125015536N15. Registered on 24 July 2024. https://www.irct.ir/trial/78113 .</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"232"},"PeriodicalIF":2.4,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12085006/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144085876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determinants of abortion among women of reproductive age in Ghana: multilevel analysis evidence from the 2022 Ghana demographic and health survey.","authors":"Begetayinoral Kussia Lahole, Kusse Urmale Mare, Maechel Maile, Wondafrash Kussia","doi":"10.1186/s12905-025-03779-z","DOIUrl":"https://doi.org/10.1186/s12905-025-03779-z","url":null,"abstract":"<p><strong>Introduction: </strong>Due to data gaps in most countries, the factors that affect the prevalence of abortion among women from a variety of social and economic backgrounds, especially in Africa, are little understood. We investigated abortion and its determinants among women of reproductive age in this study with the aim of providing policymakers in Ghana specific information.</p><p><strong>Methods: </strong>After obtaining authorization to analyze data on abortion among women of reproductive age, we looked at the data from the Ghana demographic health survey 2022 that we obtained from the DHS website. We used binary logistic regression, both bivariate and multilevel. A three-level binary logistic regression analysis was performed on community and individual-level abortion predictors, using p-values less than 0.05 and adjusted odds ratios (AOR) with 95% confidence intervals (CI).</p><p><strong>Results: </strong>In the current study, the prevalence of abortion was 39.84%. Factors associated with abortion were age group 20-24 (AOR = 1.65, 95%CI = 1.05-2.61), 25-29 (AOR = 2.55, 95%CI = 1.60-4.08), 30-34 (AOR = 2.97, 95%CI = 1.54-4.81), 35-39 (AOR = 2.54, 95%CI = 1.54-4.17), 40-44 (AOR = 4.73, 95%CI = 2.74-8.15), 45-49 (AOR = 4.73, 95%CI = 2.21-9.45), married women (AOR = 1.48, 95%CI = 1.07-2.04), women living with their partner (AOR = 1.42, 95%CI = 1.02-1.98), intention to use contraceptives (AOR = 0.73, 95%CI = 0.61-0.88), smokers (AOR = 0.05, 95%CI = 0.06-0.43), Northern region (AOR = 0.50, 95%CI = 0.26-0.96), North East region (AOR = 0.26, 95%CI = 0.11-0.59), Upper East region (AOR = 0.33, 95%CI = 0.16-0.71), and Upper West region (AOR = 0.29, 95%CI = 0.12-0.67).</p><p><strong>Conclusion: </strong>The magnitude of abortion was relatively higher than that of other African countries including Mozambique, Ghana, Côte d'Ivoire and Ethiopia. Education status, age, intention of using contraceptives, smoking, and region were determinants of abortion in Ghana. Therefore, comprehensive and culturally acceptable sexual and reproductive health services for women must be provided by those in charge. It is important to establish programs that support women's livelihood and education so that they can make educated decisions about things like using contraception and avoiding unintended pregnancies.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"227"},"PeriodicalIF":2.4,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12080172/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A non-randomized study of sexual health education on the sexual function of primigravid women.","authors":"Maryam Keshavarz, Afsaneh Ghorbani, Leila Allahqoli, Fatemeh Sarvi, Hamid Salehiniya, Ibrahim Alkatout","doi":"10.1186/s12905-025-03735-x","DOIUrl":"https://doi.org/10.1186/s12905-025-03735-x","url":null,"abstract":"<p><strong>Background: </strong>Sexual function is a particularly important aspect of pregnant women's lives that can affect mental health and family cohesion.</p><p><strong>Aim: </strong>This study aimed to determine the effect of sexual health education on sexual function in primigravida women.</p><p><strong>Methods: </strong>In a non-randomized study, primigravida women were divided into an intervention group (n = 43) and a control group (n = 43). The intervention group participated in six 60-minute sex education sessions, while the control group received no intervention. Both groups were monitored for 8 weeks. Sexual function was evaluated using the Female Sexual Function Index (FSFI) questionnaire before the intervention, at 4 weeks, and at 8 weeks post-intervention.</p><p><strong>Results: </strong>Ultimately, data from 80 patients were analyzed. The two groups did not differ significantly in terms of demographic and pre-intervention clinical characteristics. At the 4-week mark post-intervention, there was no statistically significant difference observed in the average score of the overall index of sexual performance between the pregnant women in the two groups. However, upon comparing sexual function before intervention and at 4 and 8 weeks after intervention, significant improvements were noted in desire, arousal, lubrication, orgasm, satisfaction, and pain subscale scores within the intervention group (p < 0.001). Conversely, in the control group, desire (psychological interest or motivation), arousal (physiological and emotional readiness), lubrication, and satisfaction subscale scores decreased, while the pain subscale score slightly increased between pre-intervention and the 8-week follow-up. The mean difference in the overall FSFI score before and 8 weeks after the intervention was notably higher in the intervention group (7.37 points) compared to the control group (-0.87 points (p < 0.001).</p><p><strong>Conclusion: </strong>The findings of this study highlight the transformative impact of sexual health education during pregnancy. By dispelling misconceptions and enriching knowledge, such interventions have the potential to enhance the sexual function of pregnant women significantly. These results underscore the effectiveness of integrating sexual health education into routine prenatal care, emphasizing its pivotal role in promoting the overall well-being of primiparous pregnant women.</p><p><strong>Trial registration: </strong>This study retrospectively registered with the Iranian Clinical of Trials Registry with IRCT registration number IRCT20090810002324N20 (08-04-2025) ( https://irct.behdasht.gov.ir/trial/82382 ).</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"226"},"PeriodicalIF":2.4,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12080019/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Culture, self-esteem and menstrual hygiene management among adolescent girls in Uganda: the impact of economic and family strengthening.","authors":"Flavia Namuwonge, Samuel Kizito, Vicent Ssentumbwe, Phionah Namatovu, Florence Namuli, Nhial T Tutlam, Proscovia Nabunya, Fred M Ssewamala","doi":"10.1186/s12905-025-03778-0","DOIUrl":"10.1186/s12905-025-03778-0","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;In many Sub-Saharan African countries (SSA), including Uganda, adolescent girls, especially those from low-income families, are disproportionately affected by inadequate menstrual hygiene management (MHM) facilities and supplies. This study assesses the impact of two interventions, including economic empowerment and family-strengthening interventions, on the self-esteem of adolescent girls and explores the moderating effects of cultural attitudes and menstrual hygiene knowledge.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;We analyzed longitudinal data from a 3-arm Cluster Randomized Control Trial, Suubi4Her study, with a follow-up period of 24 months (2018-2022). A total of 1260 adolescent girls, aged 14-17 years, and living within a family were recruited from 47 schools within five geopolitical districts in Southwestern Uganda. The three study arms were: control (n = 16 schools, n = 408 students), Economic Empowerment using incentivized youth development accounts (YDA) (n = 16 schools, n = 471 students), and YDA + a family strengthening intervention that uses Multiple Family Group (MFG) meetings to address adolescent girls' and family health and wellbeing (n = 15 schools, n = 381 students). We used mixed-effect linear regression models to assess the impact of economic empowerment on self-esteem, measured by the Rosenberg Self-Esteem Scale, and the moderation effect of menstrual hygiene knowledge, measured by a nine-item scale, and cultural attitudes, measured by self-reported school absence during menstrual periods.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Baseline demographic characteristics indicate no statistically significant difference across the intervention arms. We found statistically significant main effects for time (χ&lt;sup&gt;2&lt;/sup&gt;(2) = 102.07, p &lt; 0.001) and intervention-time interaction effects (χ&lt;sup&gt;2&lt;/sup&gt;(4) = 12.99, p = 0.011). Pairwise group comparisons at the different assessment time points showed no significant differences in self-esteem between YDA group and the control at baseline (β = 0.173 (-1.453, 1.108), p = 0.791), at 12 months (β = 0.372 (-0.893, 1.637), p = 0.565), and at 24 months (β = 0.153 (-0.904, 1.210), p = 0.777), indicating no significant effect of the YDA intervention alone on self-esteem. Similarly, no significant differences in self-esteem were found between the YDA + MFG group and the control at baseline (β=-0.299 (-1.713, 1.114), p = 0.678) and 12 months (β = 0.986 (-0.495, 2.468), p = 0.192). However, at 24-months follow-ups, the YDA + MFG group showed significantly higher self-esteem than the control (β = 1.282 (0.084, 2.480), p = 0.036). Additionally, those who reported school absenteeism due to cultural or religious reasons and received the YDA + MFG intervention reported higher self-esteem than usual care (β = 1.57 (0.07, 3.07), p = 0.004). No significant moderation by menstrual hygiene knowledge or cultural attitude was detected.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;The YDA + MFG intervent","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"230"},"PeriodicalIF":2.4,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12080034/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long COVID and endometriosis: a systematic review and meta-analysis.","authors":"Alexandre Vallée, Maxence Arutkin, Pierre-François Ceccaldi, Anis Feki, Jean-Marc Ayoubi","doi":"10.1186/s12905-025-03761-9","DOIUrl":"10.1186/s12905-025-03761-9","url":null,"abstract":"<p><p>Long COVID conditions entail the persistence of COVID-19-related symptoms for at least eight weeks following SARS-CoV-2 infection. The prevalence of long COVID is estimated to range from 10 to 30% among individuals infected with SARS-CoV-2. Despite its growing impact on healthcare systems, long COVID remains poorly understood. In parallel, endometriosis, a chronic inflammatory condition affecting around 10% of reproductive-age women, is marked by symptoms such as pelvic pain and infertility. The aim of this study was to assess the association between endometriosis and long COVID. We performed a systematic review of long COVID among endometriosis patients in Pubmed/Medline, Cochran Library and Science Direct databases from inception to August 2023. We independently selected studies, extracted data, assessed risk of bias, and compared endometriosis versus non endometriosis patients for long. Pooled analyses were based on random-effect models, and the I² statistic was used to quantify heterogeneity across studies. A total of 2 cross-sectional studies (N = 216,095 participants) were included. The pooled analysis comparing endometriosis to non-endometriosis patients significantly showed association for long COVID (pooled RR = 1.41 [1.31-1.52], I² = 29%, p < 0.001). Women, who are disproportionately affected by long COVID, particularly those with endometriosis, may face compounded health challenges. While our findings suggest a possible association between endometriosis and long COVID, the evidence is currently limited to two observational studies. Further research involving diverse populations and robust study designs is needed to confirm this relationship and clarify underlying mechanisms.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"229"},"PeriodicalIF":2.4,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12079877/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors affecting domestic violence against women in Iran: a scoping review.","authors":"Leila Manzouri, Maryam Seyed-Nezhad, Ghasem Rajabi-Vasokolaei, Alireza Arabi, Mohammad Moardi-Joo","doi":"10.1186/s12905-025-03770-8","DOIUrl":"10.1186/s12905-025-03770-8","url":null,"abstract":"<p><strong>Background: </strong>Domestic violence (DV) is the most common form of violence against women with the most social, psychological and economic consequences. Various factors affect DV against women. Several studies were conducted in Iran, each of which focused on a part or level of factors affecting DV. Therefore, this scoping review was conducted to determine the factors affecting violence against women in Iran.</p><p><strong>Methods: </strong>In this scoping review study, databases Magiran, IranDoc, Islamic World Science Citation Database (ISC), Scientific Information Database (SID) were used to collect studies published in Persian and databases PubMed, Scopus, Science Direct, and Web of Science from the beginning to June 2024 were searched. Google Scholar search engine was used to find relevant sources and complete the search coverage. The process of searching and selecting studies was drawn using PRISMA Diagram. To analyze the data, according to the evidence, the main factors and sub-factors were extracted by two authors independently. Then the data was sifted and sorted.</p><p><strong>Results: </strong>Out of 491 identified studies, 81 were included in this study; the sample size of these studies was 42,239. Based on the obtained results, 6 main factors and 21 sub-factors affecting DV against women are: individual factors (age, education, marriage, and children), social factors (addiction, interference of others, history of violence, divorce, family structure, marital relationship, social class, and social capital), psychological factors, pregnancy factors, economic factors (income, employment, residence status, economic class, and economic status) and cultural factors (patriarchy, tradition, cultural development, and ethnicity).</p><p><strong>Conclusion: </strong>The results of our study showed that several factors are effective on domestic violence against women, so policy makers and health system managers should look for solutions to reduce this health and social problem. Factors such as the expansion of counseling and treatment centers in comprehensive health service centers, life skills training, interventions appropriate to cultures and social norms, and the implementation of campaigns to increase awareness of DV are particularly important in reducing this phenomenon in society.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"231"},"PeriodicalIF":2.4,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12083032/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}