BMC Women's Health最新文献

{"title":"BVBlue as a diagnostic instrument for the diagnosis of bacterial vaginosis: a systematic review.","authors":"Igor Ian Wiguna, Kevin Tanoto, Valencia Hadinata, Nadir Chan, Budi Iman Santoso","doi":"10.1186/s12905-025-03615-4","DOIUrl":"https://doi.org/10.1186/s12905-025-03615-4","url":null,"abstract":"<p><strong>Background: </strong>Bacterial vaginosis (BV) refers to an imbalance in normal vaginal flora, affecting approximately 50-60% of individuals engaging in high-risk sexual behaviors. BV diagnosis traditionally relies on Amsel's criteria or Nugent's scoring, but these methods are sluggishly effective, leading to delayed treatment. BVBlue, a swift point-of-care test, holds promise as a potential diagnostic tool for BV. This systematic review aims to evaluate the accuracy of the BVBlue criteria compared with Nugent's scoring in diagnosing BV.</p><p><strong>Methods: </strong>We conducted a systematic search using designated terms in PubMed, ProQuest, and Scopus to identify all studies reporting BVBlue in diagnosing BV. We subsequently screened and critically evaluated the journals via the QUADAS-2 Quality Assessment Tool. This systematic review has been registered in PROSPERO (no. CRD42024545022).</p><p><strong>Result: </strong>Out of 19 studies identified in our research, five were ultimately included. The quality assessment results revealed that all the included studies had good quality and low risk of bias. BVBlue has a sensitivity ranging from 38% to 91.7% and a specificity ranging from 91 to 100% in diagnosing BV. Four studies endorsed the BVBlue scale because of its high sensitivity, specificity, and rapidity in diagnosing BV. However, one study advised against its use in certain populations with mixed vaginal infections because of its inability to detect variation in composition and diversity of vaginal bacterial flora, that may be sialidase-negative.</p><p><strong>Conclusion: </strong>Our systematic review revealed that BVBlue is a promising diagnostic tool for BV because of its accuracy and speed. Nevertheless, additional research is essential, particularly in elucidating the bacterial epidemiology of BV in certain countries, to validate its diagnostic credibility thoroughly.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"90"},"PeriodicalIF":2.4,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143531139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The present adenomyosis treatment status in Luzhou, China: a small scope observational cross-sectional survey.","authors":"Lingling Xie, Mengsi Yang, Xinyu Chen, Luxia Yao, Wei Xu, Qiuling Shi, Yuan Yuan","doi":"10.1186/s12905-025-03619-0","DOIUrl":"https://doi.org/10.1186/s12905-025-03619-0","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the current treatment status and management deficiencies of adenomyosis in Luzhou, China.</p><p><strong>Materials and methods: </strong>A small-scale observational cross-sectional study of patients whose imaging suggests adenomyosis from July 2018 to February 2022 at a teaching hospital in Luzhou, China. All participants (1542 patients) completed a questionnaire of 14 items, including basic information, symptoms, treatment options, outcomes, and costs. The patients' treatment options and the hysterectomy rate were evaluated.</p><p><strong>Results: </strong>The treatment options of hormone agents included combined oral contraceptive pills (COCs), gonadotropin-releasing hormone analogues (GnRH-a), levonorgestrel-releasing intrauterine system (LNG-IUS), and dienogest for 2.07, 46.04, 63.49, and 4.67% of patients, respectively. The treatment options under uterus-sparing surgery included adenomyectomy and high-intensity focused ultrasound (HIFU) treatment, presenting in 3.76 and 33.27% of patients, respectively. Finally, 458 (29.70%) patients chose a hysterectomy. The hysterectomy rate between the hormone and uterus-sparing surgery sequential hormone groups (surgery group) was not significantly different (14.8 vs. 12.7%, χ2 = 0.344, P > 0.05). However, for the focal type and patients with > 24 months delayed treatment interval, the hysterectomy rate of the hormone group was significantly higher than that of the surgery group (8.5% vs. 1.3%, χ2 = 11.722, P < 0.01 and 26.7% vs. 18.5%, χ2 = 4.906, P < 0.05, respectively).</p><p><strong>Conclusions: </strong>There were treatment delays and treatment selection bias in managing adenomyosis in Luzhou, China. Popular science education and early individualized hormone therapy are needed. Uterine-sparing surgery should be carefully selected.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"92"},"PeriodicalIF":2.4,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143531142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy comparison of PD-1/PD-L1 inhibitor monotherapy and combination with PARPis or antiangiogenic agents in advanced or recurrent endometrial cancer: a systematic review and network meta-analysis.","authors":"Shiya Ji, Xupeng Chen, Yebo Yu, Qiuping Jia, Xingxing Zhang, Zixin Gao","doi":"10.1186/s12905-025-03612-7","DOIUrl":"https://doi.org/10.1186/s12905-025-03612-7","url":null,"abstract":"<p><strong>Purpose: </strong>The network meta-analysis (NMA) was aimed to compare and assess the effectiveness of programmed cell death 1 (PD-1)/ programmed cell death ligand 1 (PD-L1) inhibitor monotherapy or combination therapy with other agents for individuals with advanced or recurrent endometrial cancer (EC).</p><p><strong>Methods: </strong>The NMA was registered on the PROSPERO website (ID: CRD42024545968) and multiple databases were queried to retrieve the articles. It assessed the progression-free survival (PFS) and overall survival (OS) of persons with advanced or recurrent EC, as well as those with deficient mismatch repair (dMMR) and proficient mismatch repair (pMMR) in terms of PFS.</p><p><strong>Results: </strong>The NMA included 12 studies involving a total of 4,515 patients. Compared to chemotherapy, the PD-1/PD-L1 inhibitor monotherapy (hazard ratio [HR], 0.59; 95% confidence interval [CI]: 0.44-0.78) in PFS, combination therapy with poly (ADP-ribose) polymerase inhibitors (PARPis) (HR, 0.53; 95% CI: 0.32-0.89) or with antiangiogenic agents (HR, 0.48; 95% CI: 0.25-0.83) all showed significant improvements in PFS. PD-1/PD-L1 inhibitor monotherapy resulted in a significantly higher OS (HR, 0.61; 95% CI: 0.37-0.97) compared to chemotherapy. Combination therapy with antiangiogenic agents demonstrated the highest efficacy in extending PFS, while the combination with PARPis had the best performance in extending OS. Patients with dMMR and pMMR subtypes derive greater benefits from PD-1/ PD-L1 inhibitor monotherapy and PD-1/PD-L1 inhibitors combined with PARPis respectively.</p><p><strong>Conclusion: </strong>Monotherapy with PD-1/PD-L1 inhibitors and combination therapies with PARPis or antiangiogenic agents demonstrate significant potential for individuals with advanced or recurrent EC.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"93"},"PeriodicalIF":2.4,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143531141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of urinary tract endometriosis with physical and mental health: a cross-sectional study.","authors":"Xuanmin Chen, Qiaojian Zou, Tingting Zhao, Guimei He, Xiaohui Wang, Yinglei Mo, Jinfeng Huang, Jiebing Chen","doi":"10.1186/s12905-025-03579-5","DOIUrl":"https://doi.org/10.1186/s12905-025-03579-5","url":null,"abstract":"<p><strong>Background: </strong>Urinary tract endometriosis (UTE) is a special type of endometriosis affecting the urinary system, yet the physical and mental health of UTE patients remain unexplored.</p><p><strong>Methods: </strong>We enrolled 92 women with UTE and another 234 with deep infiltrating endometriosis from the First Affiliated Hospital of Sun Yat-sen University. Personal information was collected via paper questionnaires. Health-related quality of life, including physical and mental health, was measured by physical component summary scale (PCS) and mental component summary scale (MCS) of the 12-item Short Form Health Survey (SF-12). Multiple linear regression analysis was conducted to identify factors influencing physical and mental health.</p><p><strong>Results: </strong>Patients in the UTE group had a higher creatinine level and detection rate of urinary leukocyte, erythrocyte and protein. The PCS score was lower in the UTE group, while the MCS was similar between two groups. Multiple linear regression analysis shown that patients using painkillers had lower PCS scores, while those aware of urologic abnormalities before surgery or with a history of more than two miscarriages had lower MCS scores.</p><p><strong>Conclusions: </strong>Our study explores the quality of life in UTE patients and identifies influencing factors. Individualized and targeted care should be added to clinical practice to prevent negative outcomes for UTE patients.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"91"},"PeriodicalIF":2.4,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143531217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expression and clinical significance of CCN5 and the oestrogen receptor in advanced breast cancer.","authors":"Guofeng Zhou, Wei Qu, Liu Yang, Aili Huang, Xinxing Gui","doi":"10.1186/s12905-025-03608-3","DOIUrl":"10.1186/s12905-025-03608-3","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to investigate the expression and clinical implications of CCN family member 5 (CCN5) and the oestrogen receptor (ER) in advanced breast cancer (BC).</p><p><strong>Methods: </strong>A total of 130 patients with advanced BC were selected for the study. Samples of normal breast tissue, ductal carcinoma in situ (DCIS), and invasive carcinoma were collected. The expression levels of CCN5 and ER in these tissues were examined using immunohistochemical methods. The correlation between expression of CCN5 and ER in different tissues and also differences in expression in invasive carcinoma were analysed. In addition, the relationship between CCN5 expression in advanced BC tissues and clinical pathological features was examined.</p><p><strong>Results: </strong>CCN5 and ER had low expression in normal breast tissues and invasive carcinoma tissues, but high expression in DCIS, with this difference being statistically significant (X² = 119.899, P < 0.001; X² = 113.524, P < 0.001, respectively). The expression of CCN5 and ER in different tissues of patients with advanced BC showed a positive correlation. Significant differences were also observed in the positive and negative expression of CCN5 and ER (X² = 56.358, P < 0.001). Moreover, the expression of CCN5 protein in advanced BC showed a statistically significant associations (P < 0.05) with the expression of the progesterone receptor (PR), human epidermal growth factor receptor 2 (HER-2), Ki-67, and P53, tumor diameter, histological grade, lymph node metastasis, pathological molecular subtype, and clinical staging.</p><p><strong>Conclusion: </strong>High expression of CCN5 and ER was observed in DCIS tissues of patients with advanced BC, with their expression being positively correlated. These findings suggest that CCN5 and ER may have a potential synergistic role in the progression of BC that influences the progression of advanced BC and can also be used to predict the effectiveness of endocrine therapy.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"89"},"PeriodicalIF":2.4,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11866700/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143522650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"NTRK rearranged spindle cell neoplasm of the uterine cervix: a rare case report and literature review.","authors":"Xiaoxia Jiang, Shao Zhang, Lin Wu, Zheng Li","doi":"10.1186/s12905-025-03574-w","DOIUrl":"10.1186/s12905-025-03574-w","url":null,"abstract":"<p><strong>Background: </strong>Neurotrophic tyrosine receptor kinase (NTRK) rearranged spindle cell neoplasm is an emerging group of molecularly defined rare soft tissue tumors, often presenting with a monotonous spindle cell morphology, infiltrative growth, and co-expression of S-100 and CD34 proteins by immunohistochemistry (IHC). Accurate diagnosis necessitates the combination of morphology, immunohistochemistry, and molecular test results, with next-generation sequencing (NGS) as the gold standard. We present a rare case of NTRK rearranged spindle cell neoplasm of the uterine cervix and review the literature to highlight the current understanding of the diagnosis and treatment of this rare disease.</p><p><strong>Case presentation: </strong>A 49-year-old perimenopausal woman presented with menorrhagia for more than a month. A biopsy of the cervix revealed a cervical spindle cell neoplasm with a tendency to be an isolated fibrous tumor. A total abdominal hysterectomy with bilateral salpingo-oophorectomy was performed and the surgical pathology suggested NTRK rearranged spindle cell neoplasm, while NGS confirmed TFG-NTRK3 fusion gene. Postoperatively, the patient refused larotrectinib maintenance therapy for economic reasons and had no sign of recurrence or metastasis at 31 months of follow-up.</p><p><strong>Conclusion: </strong>We presented the first case of cervical spindle cell neoplasm with TFG-NTRK3 gene rearrangement and retrieved 22 cases of NTRK rearranged spindle cell neoplasm of the uterine cervix from literature. The most prevalent type of gene fusion was TPM3-NTRK1, and almost all cases demonstrated S-100 and CD34 positivity by IHC. Surgery remains the initial treatment of choice and tyrosine receptor kinase (TRK) inhibitors may serve as a promising target therapy for patients with recurred or metastatic disease.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"88"},"PeriodicalIF":2.4,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11863720/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143514693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of a Breast Cancer Diagnosis on Finances and Marital Status in Young Women.","authors":"Tamara Hamlish, Michelle L Foster, Sarah Strom, Rana Jaber, M Courtney Hughes","doi":"10.1186/s12905-025-03607-4","DOIUrl":"10.1186/s12905-025-03607-4","url":null,"abstract":"<p><strong>Purpose: </strong>A breast cancer diagnosis can impact every aspect of a woman's life, particularly for women diagnosed before age 45 when they are in the process of establishing stability in their personal and professional lives. This study investigated the impact of a breast cancer diagnosis on employment, finances, and personal relationships among young breast cancer survivors.</p><p><strong>Methods: </strong>We conducted descriptive statistical analysis of survey data from 315 women diagnosed with breast cancer before age 45. Surveys were administered electronically and included 40 questions on demographics asking about employment, insurance, income, and marital status at two time points: at diagnosis and at the time the survey was completed. Descriptive and regression analyses were conducted. The McNemar-Bowker Test of Symmetry was used to calculate the significance of changes in employment, insurance, income, and marital status at the two time points.</p><p><strong>Results: </strong>We found significant changes following diagnosis in employment and insurance. Prior to diagnosis, 68.6% of respondents were employed full time, compared to 52.4% following diagnosis - falling from 212 to 162 respondents. Individuals who were unable to work increased by 14.6% after diagnosis, rising from 4 to 49 respondents. The decline in full-time employment was highest among those with a diagnosis of Stage IV cancer (33.9%), with the number of full-time worker respondents falling from 79 to 41. We found a significant change in insurance (p < .001) with a decline in individuals with private or no insurance of 4.7% and 3.4%, respectively, while those with public insurance increased by 8.1%.</p><p><strong>Conclusion: </strong>Our findings suggest that young breast cancer survivors are particularly vulnerable to changes in employment, with more than a tenfold increase in the number of young women who reported being unable to work following diagnosis. Our findings also indicate a significant shift from private to public insurance, particularly for individuals living with Stage IV cancer. These results point to opportunities to address the specific needs of young women diagnosed with breast cancer and improve their overall quality of life.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"86"},"PeriodicalIF":2.4,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11853482/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143490748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of the menopause representation questionnaire (MenoSentations-Q) among Iranian women and cross-cultural comparison with Portuguese women.","authors":"Zahra Arab Borzu, Mahmood Karimy, Mafalda Leitão, Filipa Pimenta, Rita Albergaria, Zahedeh Khoshnazar, Parisa Hosseini Koukamari","doi":"10.1186/s12905-025-03606-5","DOIUrl":"10.1186/s12905-025-03606-5","url":null,"abstract":"<p><strong>Background: </strong>Menopause represents a critical stage in middle. Examining menopausal symptoms within healthcare system requires reliable and valid instruments. The Menopause Representations Questionnaire (Menosentations-Q) is a self-report scale grounded in Leventhal's self-regulation model. This study aimed to explore the psychometric properties of this questionnaire among Iranian women.</p><p><strong>Methods: </strong>This study was conducted with women visiting healthcare centers in Saveh, Markazi province, Iran. A total of 320 eligible Iranian women and 354 Portuguese women (aged 45-65) completed the questionnaire. Structural validity was assessed using exploratory factor analysis (EFA) and confirmatory factor analysis (CFA). Internal consistency was evaluated through Cronbach's alpha and McDonald's omega. Convergent and divergent validity were determined using average shared variance, maximum shared variance, construct reliability, and Fornell and Larcker's method. Cross-cultural validity was performed by multigroup CFA to assess invariance between two culturally distinct samples (Iranian and Portuguese).</p><p><strong>Results: </strong>The Content Validity Ratio (CVR) and Content Validity Index (CVI) were 0.96 and 0.98, respectively, indicating strong content and face validity. EFA of 22 items revealed four factors-identity, positive and negative consequences, and control/awareness/cause factors, accounting for 61.29% of the total variance. CFA indicated good model fit (CFI = 0.96, TLI = 0.95, χ2/df = 1.74, GFI = 0.91, AGFI = 0.89, RMSEA = 0.04). Cronbach's alpha (0.90) and McDonald's omega (0.92) indicated good internal consistency. Convergent and discriminant validity values of MenoSentations-Q were also acceptable. Also, the instrument showed invariance between the two cultural groups.</p><p><strong>Conclusions: </strong>The Persian adaptation of MenoSentations-Q demonstrated strong validity and reliability. Furthermore, the comparable responses between Portuguese and Iranian participants suggest shared representations of menopause across these cultures. Given the significance of menopause, tailored educational programs and interventions are essential to address potential challenges during this life stage. Employing standardized tools such as the Menopsentations-Q can support the development of effective strategies, including educational initiatives, support programs, and targeted interventions, to empower women and enhance their well-being during this transitional phase.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"87"},"PeriodicalIF":2.4,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11852873/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143499293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between overactive bladder and female sexual frequency: a cross-sectional analysis of the National Health and nutrition examination survey data.","authors":"Bo Zhang, Yi Gu, Yuanyuan Li, Yiming Chen, Xingliang Feng","doi":"10.1186/s12905-025-03611-8","DOIUrl":"10.1186/s12905-025-03611-8","url":null,"abstract":"<p><strong>Background: </strong>Overactive bladder (OAB) and female sexual dysfunction (FSD) are both common problems in women, but the association between OAB and FSD lacks a large sample study. The purpose of this cross-sectional study was to investigate the association between OAB and FSD.</p><p><strong>Methods: </strong>Data for this study were obtained from the 2007-2016 National Health and Nutrition Examination Survey (NHANES) for women aged 20-59 years. OAB was qualified with the aid of the overactive bladder symptom score (OABSS), which was obtained by adding the nocturia score and the urge urinary incontinence score, and participants with a total score ≥ 3 were considered to suffer from OAB. The FSD was defined as a sexual frequency of less than 12 times per year. After adjusting for covariates including basic demographic information, social information (e.g., marital status), gynecological (e.g., abnormal menstruation), and significant medical comorbidities, the association between OAB and FSD was assessed using survey-weighted logistic regression mode. In addition, subgroup analysis and sensitivity analysis were used to further assess the reliability of the findings.</p><p><strong>Results: </strong>A total of 5590 women aged 20-59 were eligible in the final analysis from 2007 to 2016 NHANES. 30.43% of participants (n = 1701) were identified as FSD reporting sexual frequency of 0-11 times/year, while 69.57% of participants (n = 3889) were identified as normal female sexual function reporting sexual frequency > 11 times/year. We performed logistic regression analysis to examine the association between OAB and FSD. The results demonstrated that participants with OAB (OABSS < 3) were 23% more likely to report lower sexual frequency (≤ 11) than those without OAB (OABSS ≥ 3) after adjusting fully for demographics, social history, gynecologic history and significant medical conditions (OR: 1.23, 95%CI: 1.01-1.49, P = 0.040).</p><p><strong>Conclusion: </strong>The study demonstrated the positive association between OAB and FSD measured by low sexual frequency among women 20-59 years old in the U.S. population; it is necessary to perform more comprehensive cohort studies to gain more profound understanding of the association between them.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"84"},"PeriodicalIF":2.4,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11849308/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143490803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative analysis of spinal anesthesia versus general anesthesia in single-port access laparoscopic adnexal surgery: a propensity score matching study.","authors":"Kyung Jin Eoh, Jung Hwan Ahn, Ji Sun Park, Sun Hwa Park, Yeon Seo Cho, Seung Woo Song, Kyoung-Hee Han, San-Hui Lee","doi":"10.1186/s12905-025-03604-7","DOIUrl":"10.1186/s12905-025-03604-7","url":null,"abstract":"<p><p>This study evaluated the safety and efficacy of spinal anesthesia as an alternative to general anesthesia in single-port access (SPA) laparoscopic adnexal surgeries. 110 patients were recruited and, after propensity score matching, 63 (general anesthesia: 42, spinal anesthesia: 21) were analyzed. During surgery, the Trendelenburg position was limited to 15°, and CO2 pressure maintained at 8-12 mmHg. Postoperative pain and nausea/vomiting scores were assessed up to 48 h post-surgery. No significant differences in patient characteristics were noted between groups. Immediately postoperative, the spinal anesthesia group showed significantly lower pain scores (4.74 ± 1.48 in spinal anesthesia vs. 0.67 ± 0.66 in general anesthesia; p <.001) and nausea/vomiting scores (p =.027). Intraoperative hypotension occurred in both groups (28.6% in spinal anesthesia vs. 33.3% in general anesthesia; p =.774) and was managed with ephedrine. No other intraoperative or postoperative complications were noted. Conclusively, spinal anesthesia is a viable and safe option for SPA laparoscopic salpingo-oophorectomy, effectively reducing immediate postoperative pain and nausea/vomiting.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"83"},"PeriodicalIF":2.4,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11849393/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143490457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}