BMC Women's Health最新文献

{"title":"MCT-modified ketogenic diet as an adjunct to standard treatment regimen could alleviate clinical symptoms in women with endometriosis.","authors":"Fatemeh Naeini, Fatemeh Davari Tanha, Maryam Mahmoudi, Hastimansooreh Ansar, Mohammad Javad Hosseinzadeh-Attar","doi":"10.1186/s12905-025-03798-w","DOIUrl":"https://doi.org/10.1186/s12905-025-03798-w","url":null,"abstract":"<p><strong>Background: </strong>Endometriosis as a chronic gynecological condition impairs the quality of life of affected women because it usually accompanied by painful clinical symptoms such as persistent severe acyclic pelvic pain, dyspareunia, and dyschezia. The aim of the present study was to examine the effects of MCT-modified ketogenic diet as an adjunct to standard treatment regimen in women with endometriosis.</p><p><strong>Methods: </strong>This is a 12-weeks randomized controlled clinical trial that was conducted on 50 patients with endometriosis who referred to Yas hospital complex infertility clinic, Tehran, Iran. Participants were randomly allocated to intervention group receiving MCT-modified ketogenic diet plus standard treatment regimen (n = 25) and control group receiving standard treatment regimen (n = 25). Clinical symptoms, anthropometric parameters, lipid profile, and serum aminotransferases were measured at the beginning and end of the study. Statistical analysis was done by SPSS version 27 software and P-value < 0.05 was regarded significant.</p><p><strong>Results: </strong>Finally, 44 patients including 19 subjects in the intervention group and 25 subjects in the control group completed the study. Dyspareunia and dyschezia significantly reduced in the MCT-modified ketogenic diet group compared to the control group at the end of the study (P = 0.02 and P = 0.001, respectively). Also, there was a marginally significant reduction in the final values of pelvic pain (P = 0.07). However, no significant differences in the final value of anthropometric indices including weight, BMI, and WC, serum levels of TG, TC, HDL-C, LDL-C, and aminotransferases including ALT and AST was detected.</p><p><strong>Conclusions: </strong>MCT-modified ketogenic diet as an adjunct to standard treatment regimen could alleviate clinical symptoms including pelvic pain, dyspareunia, and dyschezia in women with endometriosis.</p><p><strong>Trial registration: </strong>Iranian Registry of Clinical Trials IRCT20131125015536N15. Registered on 24 July 2024. https://www.irct.ir/trial/78113 .</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"232"},"PeriodicalIF":2.4,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144085876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determinants of abortion among women of reproductive age in Ghana: multilevel analysis evidence from the 2022 Ghana demographic and health survey.","authors":"Begetayinoral Kussia Lahole, Kusse Urmale Mare, Maechel Maile, Wondafrash Kussia","doi":"10.1186/s12905-025-03779-z","DOIUrl":"https://doi.org/10.1186/s12905-025-03779-z","url":null,"abstract":"<p><strong>Introduction: </strong>Due to data gaps in most countries, the factors that affect the prevalence of abortion among women from a variety of social and economic backgrounds, especially in Africa, are little understood. We investigated abortion and its determinants among women of reproductive age in this study with the aim of providing policymakers in Ghana specific information.</p><p><strong>Methods: </strong>After obtaining authorization to analyze data on abortion among women of reproductive age, we looked at the data from the Ghana demographic health survey 2022 that we obtained from the DHS website. We used binary logistic regression, both bivariate and multilevel. A three-level binary logistic regression analysis was performed on community and individual-level abortion predictors, using p-values less than 0.05 and adjusted odds ratios (AOR) with 95% confidence intervals (CI).</p><p><strong>Results: </strong>In the current study, the prevalence of abortion was 39.84%. Factors associated with abortion were age group 20-24 (AOR = 1.65, 95%CI = 1.05-2.61), 25-29 (AOR = 2.55, 95%CI = 1.60-4.08), 30-34 (AOR = 2.97, 95%CI = 1.54-4.81), 35-39 (AOR = 2.54, 95%CI = 1.54-4.17), 40-44 (AOR = 4.73, 95%CI = 2.74-8.15), 45-49 (AOR = 4.73, 95%CI = 2.21-9.45), married women (AOR = 1.48, 95%CI = 1.07-2.04), women living with their partner (AOR = 1.42, 95%CI = 1.02-1.98), intention to use contraceptives (AOR = 0.73, 95%CI = 0.61-0.88), smokers (AOR = 0.05, 95%CI = 0.06-0.43), Northern region (AOR = 0.50, 95%CI = 0.26-0.96), North East region (AOR = 0.26, 95%CI = 0.11-0.59), Upper East region (AOR = 0.33, 95%CI = 0.16-0.71), and Upper West region (AOR = 0.29, 95%CI = 0.12-0.67).</p><p><strong>Conclusion: </strong>The magnitude of abortion was relatively higher than that of other African countries including Mozambique, Ghana, Côte d'Ivoire and Ethiopia. Education status, age, intention of using contraceptives, smoking, and region were determinants of abortion in Ghana. Therefore, comprehensive and culturally acceptable sexual and reproductive health services for women must be provided by those in charge. It is important to establish programs that support women's livelihood and education so that they can make educated decisions about things like using contraception and avoiding unintended pregnancies.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"227"},"PeriodicalIF":2.4,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12080172/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A non-randomized study of sexual health education on the sexual function of primigravid women.","authors":"Maryam Keshavarz, Afsaneh Ghorbani, Leila Allahqoli, Fatemeh Sarvi, Hamid Salehiniya, Ibrahim Alkatout","doi":"10.1186/s12905-025-03735-x","DOIUrl":"https://doi.org/10.1186/s12905-025-03735-x","url":null,"abstract":"<p><strong>Background: </strong>Sexual function is a particularly important aspect of pregnant women's lives that can affect mental health and family cohesion.</p><p><strong>Aim: </strong>This study aimed to determine the effect of sexual health education on sexual function in primigravida women.</p><p><strong>Methods: </strong>In a non-randomized study, primigravida women were divided into an intervention group (n = 43) and a control group (n = 43). The intervention group participated in six 60-minute sex education sessions, while the control group received no intervention. Both groups were monitored for 8 weeks. Sexual function was evaluated using the Female Sexual Function Index (FSFI) questionnaire before the intervention, at 4 weeks, and at 8 weeks post-intervention.</p><p><strong>Results: </strong>Ultimately, data from 80 patients were analyzed. The two groups did not differ significantly in terms of demographic and pre-intervention clinical characteristics. At the 4-week mark post-intervention, there was no statistically significant difference observed in the average score of the overall index of sexual performance between the pregnant women in the two groups. However, upon comparing sexual function before intervention and at 4 and 8 weeks after intervention, significant improvements were noted in desire, arousal, lubrication, orgasm, satisfaction, and pain subscale scores within the intervention group (p < 0.001). Conversely, in the control group, desire (psychological interest or motivation), arousal (physiological and emotional readiness), lubrication, and satisfaction subscale scores decreased, while the pain subscale score slightly increased between pre-intervention and the 8-week follow-up. The mean difference in the overall FSFI score before and 8 weeks after the intervention was notably higher in the intervention group (7.37 points) compared to the control group (-0.87 points (p < 0.001).</p><p><strong>Conclusion: </strong>The findings of this study highlight the transformative impact of sexual health education during pregnancy. By dispelling misconceptions and enriching knowledge, such interventions have the potential to enhance the sexual function of pregnant women significantly. These results underscore the effectiveness of integrating sexual health education into routine prenatal care, emphasizing its pivotal role in promoting the overall well-being of primiparous pregnant women.</p><p><strong>Trial registration: </strong>This study retrospectively registered with the Iranian Clinical of Trials Registry with IRCT registration number IRCT20090810002324N20 (08-04-2025) ( https://irct.behdasht.gov.ir/trial/82382 ).</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"226"},"PeriodicalIF":2.4,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12080019/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Culture, self-esteem and menstrual hygiene management among adolescent girls in Uganda: the impact of economic and family strengthening.","authors":"Flavia Namuwonge, Samuel Kizito, Vicent Ssentumbwe, Phionah Namatovu, Florence Namuli, Nhial T Tutlam, Proscovia Nabunya, Fred M Ssewamala","doi":"10.1186/s12905-025-03778-0","DOIUrl":"10.1186/s12905-025-03778-0","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;In many Sub-Saharan African countries (SSA), including Uganda, adolescent girls, especially those from low-income families, are disproportionately affected by inadequate menstrual hygiene management (MHM) facilities and supplies. This study assesses the impact of two interventions, including economic empowerment and family-strengthening interventions, on the self-esteem of adolescent girls and explores the moderating effects of cultural attitudes and menstrual hygiene knowledge.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;We analyzed longitudinal data from a 3-arm Cluster Randomized Control Trial, Suubi4Her study, with a follow-up period of 24 months (2018-2022). A total of 1260 adolescent girls, aged 14-17 years, and living within a family were recruited from 47 schools within five geopolitical districts in Southwestern Uganda. The three study arms were: control (n = 16 schools, n = 408 students), Economic Empowerment using incentivized youth development accounts (YDA) (n = 16 schools, n = 471 students), and YDA + a family strengthening intervention that uses Multiple Family Group (MFG) meetings to address adolescent girls' and family health and wellbeing (n = 15 schools, n = 381 students). We used mixed-effect linear regression models to assess the impact of economic empowerment on self-esteem, measured by the Rosenberg Self-Esteem Scale, and the moderation effect of menstrual hygiene knowledge, measured by a nine-item scale, and cultural attitudes, measured by self-reported school absence during menstrual periods.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Baseline demographic characteristics indicate no statistically significant difference across the intervention arms. We found statistically significant main effects for time (χ&lt;sup&gt;2&lt;/sup&gt;(2) = 102.07, p &lt; 0.001) and intervention-time interaction effects (χ&lt;sup&gt;2&lt;/sup&gt;(4) = 12.99, p = 0.011). Pairwise group comparisons at the different assessment time points showed no significant differences in self-esteem between YDA group and the control at baseline (β = 0.173 (-1.453, 1.108), p = 0.791), at 12 months (β = 0.372 (-0.893, 1.637), p = 0.565), and at 24 months (β = 0.153 (-0.904, 1.210), p = 0.777), indicating no significant effect of the YDA intervention alone on self-esteem. Similarly, no significant differences in self-esteem were found between the YDA + MFG group and the control at baseline (β=-0.299 (-1.713, 1.114), p = 0.678) and 12 months (β = 0.986 (-0.495, 2.468), p = 0.192). However, at 24-months follow-ups, the YDA + MFG group showed significantly higher self-esteem than the control (β = 1.282 (0.084, 2.480), p = 0.036). Additionally, those who reported school absenteeism due to cultural or religious reasons and received the YDA + MFG intervention reported higher self-esteem than usual care (β = 1.57 (0.07, 3.07), p = 0.004). No significant moderation by menstrual hygiene knowledge or cultural attitude was detected.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;The YDA + MFG intervent","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"230"},"PeriodicalIF":2.4,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12080034/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long COVID and endometriosis: a systematic review and meta-analysis.","authors":"Alexandre Vallée, Maxence Arutkin, Pierre-François Ceccaldi, Anis Feki, Jean-Marc Ayoubi","doi":"10.1186/s12905-025-03761-9","DOIUrl":"10.1186/s12905-025-03761-9","url":null,"abstract":"<p><p>Long COVID conditions entail the persistence of COVID-19-related symptoms for at least eight weeks following SARS-CoV-2 infection. The prevalence of long COVID is estimated to range from 10 to 30% among individuals infected with SARS-CoV-2. Despite its growing impact on healthcare systems, long COVID remains poorly understood. In parallel, endometriosis, a chronic inflammatory condition affecting around 10% of reproductive-age women, is marked by symptoms such as pelvic pain and infertility. The aim of this study was to assess the association between endometriosis and long COVID. We performed a systematic review of long COVID among endometriosis patients in Pubmed/Medline, Cochran Library and Science Direct databases from inception to August 2023. We independently selected studies, extracted data, assessed risk of bias, and compared endometriosis versus non endometriosis patients for long. Pooled analyses were based on random-effect models, and the I² statistic was used to quantify heterogeneity across studies. A total of 2 cross-sectional studies (N = 216,095 participants) were included. The pooled analysis comparing endometriosis to non-endometriosis patients significantly showed association for long COVID (pooled RR = 1.41 [1.31-1.52], I² = 29%, p < 0.001). Women, who are disproportionately affected by long COVID, particularly those with endometriosis, may face compounded health challenges. While our findings suggest a possible association between endometriosis and long COVID, the evidence is currently limited to two observational studies. Further research involving diverse populations and robust study designs is needed to confirm this relationship and clarify underlying mechanisms.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"229"},"PeriodicalIF":2.4,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12079877/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors affecting domestic violence against women in Iran: a scoping review.","authors":"Leila Manzouri, Maryam Seyed-Nezhad, Ghasem Rajabi-Vasokolaei, Alireza Arabi, Mohammad Moardi-Joo","doi":"10.1186/s12905-025-03770-8","DOIUrl":"10.1186/s12905-025-03770-8","url":null,"abstract":"<p><strong>Background: </strong>Domestic violence (DV) is the most common form of violence against women with the most social, psychological and economic consequences. Various factors affect DV against women. Several studies were conducted in Iran, each of which focused on a part or level of factors affecting DV. Therefore, this scoping review was conducted to determine the factors affecting violence against women in Iran.</p><p><strong>Methods: </strong>In this scoping review study, databases Magiran, IranDoc, Islamic World Science Citation Database (ISC), Scientific Information Database (SID) were used to collect studies published in Persian and databases PubMed, Scopus, Science Direct, and Web of Science from the beginning to June 2024 were searched. Google Scholar search engine was used to find relevant sources and complete the search coverage. The process of searching and selecting studies was drawn using PRISMA Diagram. To analyze the data, according to the evidence, the main factors and sub-factors were extracted by two authors independently. Then the data was sifted and sorted.</p><p><strong>Results: </strong>Out of 491 identified studies, 81 were included in this study; the sample size of these studies was 42,239. Based on the obtained results, 6 main factors and 21 sub-factors affecting DV against women are: individual factors (age, education, marriage, and children), social factors (addiction, interference of others, history of violence, divorce, family structure, marital relationship, social class, and social capital), psychological factors, pregnancy factors, economic factors (income, employment, residence status, economic class, and economic status) and cultural factors (patriarchy, tradition, cultural development, and ethnicity).</p><p><strong>Conclusion: </strong>The results of our study showed that several factors are effective on domestic violence against women, so policy makers and health system managers should look for solutions to reduce this health and social problem. Factors such as the expansion of counseling and treatment centers in comprehensive health service centers, life skills training, interventions appropriate to cultures and social norms, and the implementation of campaigns to increase awareness of DV are particularly important in reducing this phenomenon in society.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"231"},"PeriodicalIF":2.4,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12083032/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of depression and anxiety among working women in Saudi Arabia: psychosocial and perinatal correlates.","authors":"Deemah AlAteeq, Shouq Mohammed AlNujaim, Abdullah H AlGharbi","doi":"10.1186/s12905-025-03776-2","DOIUrl":"10.1186/s12905-025-03776-2","url":null,"abstract":"<p><strong>Background: </strong>Women comprise a sizeable portion of the workforce in various industries. They might face many challenges that affect their mental well-being. Hence, a study that addresses working women's psychosocial and perinatal aspects mandates the necessity to fill the void and deficiencies related to clinical research.</p><p><strong>Objectives: </strong>To explore the prevalence of depression and anxiety among working women in Saudi Arabia and its psychosocial and perinatal correlations.</p><p><strong>Methods: </strong>This cross-sectional study involved 580 working women from Riyadh, Saudi Arabia, who participated via convenience sampling. An online-based questionnaire was used to collect data, including sociodemographic, occupational, medical, and perinatal data. The Patient Health Questionnaire (PHQ-9) and Generalized Anxiety Disorder 7 (GAD-7) were used to assess depression and anxiety.</p><p><strong>Results: </strong>More than half (56.4%) had a pregnancy history, half of them took maternity leave (49%), and most needed additional leave (65.2%). Half of the participants had mild to moderate levels of depression and anxiety, 50.2% and 49%, respectively. A positive correlation was found between depression and anxiety (p-value = < 0.001). Participants who drank alcohol or had a lower mean score of total pregnancies had a significantly higher prevalence of moderately severe to severe depression (p = < 0.05). And smokers had a significantly higher rate of severe anxiety (p = < 0.01). Participants previously diagnosed with a psychiatric disorder displayed a higher risk of severe depression and anxiety (p < 0.001).</p><p><strong>Conclusion: </strong>The findings of this study highlight the significant prevalence of mild to moderate level of depression and anxiety among working women in Saudi Arabia and their strong association with various psychosocial and perinatal factors. These results underline the urgent need for comprehensive mental health support and interventions tailored to the unique challenges faced by working women in the region.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"228"},"PeriodicalIF":2.4,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12079880/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Geospatial inequalities in women's malnutrition in Pakistan.","authors":"Lubna Naz, Amjad Ali, Sabina Yasmin, Kassahun Trueha","doi":"10.1186/s12905-025-03752-w","DOIUrl":"https://doi.org/10.1186/s12905-025-03752-w","url":null,"abstract":"<p><strong>Background: </strong>In developing countries, regional disparities in maternal malnutrition are a major deterrent to development. Inadequate nutrition and poor health among women not only affect their quality of life but also the well-being of their children, risking the future generation of the country. This study examines the spatial distribution of malnutrition at the extreme quantiles of Body Mass Index-severe thinness and underweight at the lower quantile and over-weight and obese at the upper quantile- and associated risk factors among women in Pakistan using Bayesian additive quantile regression.</p><p><strong>Methods: </strong>A sample of 5,252 of the currently non-pregnant and non-lactating married women aged 15-49 was taken from Pakistan Demographic and Health Survey 2017-18. The response variable was the women's nutritional status measured in body mass index (weight in kilograms/height in meters squared) of women. Following WHO guidelines, we used four indicators of BMI, as follows: severe thinness (BMI < 16 kg/m2); underweight (BMI < 18.5 kg/m2); Overweight (BMI > 24 kg/m2); and obese (BMI >  = 30 kg/m2). A set of explanatory variables comprising women's characteristics and household related variables were used to assess their association with the likelihood of various forms of malnutrition. The structured Bayesian Geo-additive Quantile regression approach was employed to examine the association of the explanatory variables with the entire conditional distribution of the response variable.</p><p><strong>Results: </strong>The sizable regional variation was found in malnutrition among reproductive age women. Women living in urban areas are more likely to become overweight (mean: 0.3; 95% CI: 0.06, 0.58) than their rural counterparts. Working women are less prone to obesity (mean: -0.51; 95% CI: -0.79, -0.23). Women with unimproved toilet are more likely to become overweight (mean: 0.7; 95%CI: 0.34., 1.04) and obese (mean: 0.90; 95%CI: 0.48, 1.33).</p><p><strong>Conclusions: </strong>Findings underscore the need for targeted interventions to address the complex and varied challenges posed by women's malnutrition.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"225"},"PeriodicalIF":2.4,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12079983/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The burden of ischemic heart disease among women of childbearing age in China from 1990 to 2021, and projections for the next 15 years.","authors":"Chuankun Zhang, Penghui Yang, Qijian Yi","doi":"10.1186/s12905-025-03773-5","DOIUrl":"10.1186/s12905-025-03773-5","url":null,"abstract":"<p><strong>Background: </strong>There are no studies on the burden of ischemic heart disease (IHD) among women of childbearing age (WCBA) in China. This study aims to describe the IHD burden among WCBA in China from 1990 to 2021, predict the trends over the next 15 years, and identify the contributing factors associated with IHD-related deaths.</p><p><strong>Methods: </strong>The data was extracted from the Global Burden of Disease Database 2021. The Direct age-standardized method was used to estimate the age-standardized (AS) prevalence rate (ASPR), mortality rate (ASMR), incidence rate (ASIR), and disability-adjusted life years rate (ASDR) of IHD among WCBA. Joinpoint regression analysis was used to analyze the Annual Percent Change and Average Annual Percent Change from 1990 to 2021. The Autoregressive Integrated Moving Average model was used to predict the trend over the next 15 years.</p><p><strong>Results: </strong>From 1990 to 2021, the ASPR and ASIR increased by 17.44% and 25.83%, culminating in 616.50 (95% UI, 498.42-762.38) and 79.93 (95% UI, 49.43-113.88) cases per 100,000 individuals. Conversely, the ASMR and ASDR declined to 5.17 (95% UI, 4.14-6.33) and 261.24 (95% UI, 212.03-318.03) cases per 100,000 individuals. Over the next 15 years, the ASPR is projected to increase by 25.74%, culminating in 775.20 (95% UI, 637.98-912.42) cases per 100,000 individuals. The main contributor to increased IHD-related deaths among WCBA in China was high low-density lipoprotein.</p><p><strong>Conclusions: </strong>Despite the significant decline in the ASMR and ASDR of IHD among WCBA in China over the last 30 years, the ASPR and ASIR continue to increase. Additionally, the ASPR is projected to rise over the next 15 years. These findings emphasize that effective measures and timely interventions are needed to reduce the disease burden.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"220"},"PeriodicalIF":2.4,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12070791/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143975787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes following conization and factors on HPV regression among young females in Wuxi.","authors":"Meng Sun, Bingjie Xu, Jinjin Yu, Yibo Wu","doi":"10.1186/s12905-025-03769-1","DOIUrl":"10.1186/s12905-025-03769-1","url":null,"abstract":"<p><strong>Purpose: </strong>It is crucial to prioritize the detection of precancerous lesions in clinical practice, especially in young women who have not yet made decisions about family planning. Herein, we conducted a retrospective study to track HPV regression among young females who underwent conization in the past five years and identify predictors of persistent HPV infection.</p><p><strong>Methods: </strong>We involved 400 women under the age of 35, who underwent colposcopy-guided biopsy after primary infection with high-risk HPV at the affiliated Hospital of Jiangnan University and were histologically confirmed with LSIL/HSIL between June 2018 and December 2022. Follow-up data was collected at 3 months, 6 months, 12 months and 24 months postoperatively. Clinical characteristics, including age, BMI, marital status, gravidity, contraception method, sexual history, HPV infection duration, HPV vaccination status, preoperative HPV, and cytology status, were analyzed by SPSS 20.0 software.</p><p><strong>Results: </strong>A total of 400 patients aged 18 to 35 were included, with 354 (88.5%) undergoing cervical biopsy and 92 (23%) undergoing cervical conization. There were no significant differences in age, BMI, marital status, pregnancy history, and HPV vaccination between patients with persistent HPV infection and those with HPV regression after conization. However, the timing of first sexual activity and the use of condom contraception had a statistically significant impact on HPV status.</p><p><strong>Conclusions: </strong>Duration of sexual life may play a significant role in the development of cervical precancerous, showing a positive correlation. Condoms for contraception can promote HPV regression by creating a physical barrier that blocks the transmission of HPV. Regular follow-up intervals following cervical conization are of greater significance than HPV vaccination.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"223"},"PeriodicalIF":2.4,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12070572/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143970981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}