BMC Women's Health最新文献

{"title":"Diagnostic value of contrast-enhanced ultrasound in endometrial lesions.","authors":"Yingqi Lin, Fangfei Su, Linxue Qian","doi":"10.1186/s12905-025-03860-7","DOIUrl":"10.1186/s12905-025-03860-7","url":null,"abstract":"<p><strong>Background: </strong>To quantitatively analyse the contrast-enhanced ultrasound (CEUS) parameters of endometrial lesions and explore the differences in CEUS parameters between benign and malignant endometrial lesions.</p><p><strong>Methods: </strong>The study enrolled 316 patients who were diagnosed with endometrial lesions and confirmed with histopathology. All patients underwent 2D ultrasonography and CEUS with SonoVue before surgery. There were fifteen imaging parameters were included in this study.</p><p><strong>Results: </strong>A total of 236 patients were included in this study, with 204 and 32 patients having benign lesions and malignant lesions, respectively. The malignant lesion group had a higher intensity ratio of maximum echo (Imax), 50% rise slope, and 10%-90% rising slope; lower 50% fall slope; shorter time to peak (TTP), rise time (RT), fall time, fall half time, and mean transit time; and larger area under the curve, area under the wash-in curve (WinAUC), area under the wash-out curve, and area under the wash-in and wash-out curve than the benign lesion group. The logistic regression showed that Imax, TTP, wash-in rate (WinR = WinAUC / RT), and age were related to the diagnosis of benign and malignant endometrial lesions. The following logistic regression model was then obtained: In(benign/malignant) = -4.645 + 0.007Imax-0.549ttp + 0.119age + 0.002WinR. The sensitivity and specificity of the model were 93.8% and 92.2%, respectively.</p><p><strong>Conclusion: </strong>CEUS can provide both qualitative and quantitative information on endometrial angiogenesis and provide a new method for the preoperative differentiation of benign and malignant endometrial lesions.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"338"},"PeriodicalIF":2.4,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12239469/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144599471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cross-Cultural adaptation and validation of adolescent menstrual bleeding questionnaire in a Turkish sample.","authors":"Melike Punduk Yilmaz, Ismail Yilmaz, Iclal Ilknur Ozdemir, Selma Dagci, Filiz Yarsilikal Guleroglu, Ali Cetin","doi":"10.1186/s12905-025-03889-8","DOIUrl":"10.1186/s12905-025-03889-8","url":null,"abstract":"<p><strong>Background: </strong>To evaluate the psychometric properties and cross-cultural validity of the Turkish version of the adolescent Menstrual Bleeding Questionnaire (aMBQ) through comprehensive reliability and validity analyses.</p><p><strong>Methods: </strong>We conducted a two-phase methodological study involving translation/cross-cultural adaptation and psychometric validation using standardized guidelines. The validation phase included 181 adolescents aged 12-18 years. Tools included the Turkish aMBQ and Menstrual Practice Needs Scale (MPNS). Reliability was assessed through internal consistency (Cronbach's alpha), test-retest reliability (n = 30, two-week interval), and item analysis. For validity assessment, the sample was randomly split into two subsets for exploratory (n = 91) and confirmatory (n = 90) factor analyses, with convergent validity testing and known-groups comparison.</p><p><strong>Results: </strong>Factor analysis revealed a three-dimensional structure explaining 68.4% of total variance: Bleeding Severity, Daily Activities Impact, and Social/School Impact (factor loadings: 0.685-0.845). The instrument demonstrated excellent internal consistency (Cronbach's α = 0.892) and test-retest reliability (ICC = 0.876, 95% CI: 0.841-0.912). Confirmatory factor analysis showed good model fit (CFI = 0.942, RMSEA = 0.048). The aMBQ correlated significantly with MPNS scores (r = 0.684, p < 0.001) and effectively discriminated between severity groups across all components (Cohen's d = 1.85-2.12). Content validity indices met acceptance criteria (I-CVI ≥ 0.78, S-CVI ≥ 0.90).</p><p><strong>Conclusion: </strong>The Turkish aMBQ demonstrates robust psychometric properties and structural validity, supporting its use in clinical and research settings. The three-factor structure provides comprehensive assessment of menstrual bleeding impact among Turkish adolescents, enabling standardized evaluation of menstrual health in Turkish healthcare settings.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"340"},"PeriodicalIF":2.4,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12239434/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144599470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Entero-vascular fistula following radiotherapy in a patient with recurrent cervical cancer post-pelvic exenteration: a case report.","authors":"In Sun Hwang, Soo Young Hur","doi":"10.1186/s12905-025-03840-x","DOIUrl":"10.1186/s12905-025-03840-x","url":null,"abstract":"<p><strong>Background: </strong>Total pelvic exenteration (PE) is a surgical resection of all pelvic organs used as a palliative treatment for locally advanced or recurrent pelvic malignancies. This case report describes an entero-vascular fistula as a severe complication following radiotherapy in a patient with recurrent cervical cancer who underwent PE.</p><p><strong>Case presentation: </strong>We present the case of a 47-year-old woman who was diagnosed with cervical cancer at the age of 43 years, classified as FIGO stage IIB. She underwent a radical hysterectomy followed by concurrent chemoradiotherapy (CCRT). In 2023, she developed a recto-urethral fistula and subsequently underwent PE. In March 2024, she was admitted for right buttock and leg pain. An evaluation revealed bone metastasis in the lumbar vertebrae, left iliac bone, and sacrum, for which local radiotherapy was administered. Later, she complained of bloody discharge from a sacral fistula and upper abdominal pain. Her blood pressure was 105/65 mmHg, heart rate 75 beats per minute (BPM), and hemoglobin level was 7.8 g/dL, prompting an emergency blood transfusion. Abdomino-pelvic computed tomography (APCT) scan and esophagogastroduodenoscopy (EGD) revealed a large amount of bloody fluid in the stomach and suggested communication with the bowel loop. CT angiography showed contrast extravasation from the left external iliac artery and a large hematoma. A stent graft was inserted at the site of the entero-vascular fistula to achieve embolization.</p><p><strong>Conclusion: </strong>This case highlights an entero-vascular fistula as one of the severe complications following PE and radiotherapy for recurrent cervical cancer. Patients who have undergone multimodal treatment, including PE, may have a pelvic condition that is more vulnerable to radiation. Therefore, the complications that may arise from radiation therapy, such as fistula formation, could be higher compared to patients who have not undergone PE.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"339"},"PeriodicalIF":2.4,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12239481/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144599472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology of the global burden of atrial fibrillation among women of child-bearing age, 1990-2021: insights from the Global Burden of Disease Study 2021.","authors":"Shuwen Chen, Junpeng Xiong, Peiyang Zheng, Ronghui Yu","doi":"10.1186/s12905-025-03871-4","DOIUrl":"10.1186/s12905-025-03871-4","url":null,"abstract":"","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"335"},"PeriodicalIF":2.4,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12232735/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144574838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Women's experiences of life and healthcare after levator ani avulsion: a qualitative interview study.","authors":"Karin Estendahl, Louise Danielsson","doi":"10.1186/s12905-025-03892-z","DOIUrl":"10.1186/s12905-025-03892-z","url":null,"abstract":"<p><strong>Background: </strong>Levator ani muscle (LAM) avulsion affects approximately 10-20% of women following vaginal delivery and results in permanent damage to the pelvic floor. This condition is a significant risk factor for pelvic floor dysfunction, including pelvic organ prolapse (POP). Despite its high prevalence, we lack knowledge and clinical guidelines regarding the prevention, diagnosis, management, and treatment of LAM. Women's views of living with this injury need to be acknowledged and explored.</p><p><strong>Aim: </strong>To explore women's experiences of living with a LAM avulsion and their experiences of associated contact with healthcare.</p><p><strong>Methods: </strong>A qualitative interview study in which the data were analysed using qualitative content analysis according to Graneheim and Lundman. Fifteen women aged 33-55 years with diagnosed LAM avulsion participated. Videoconference interviews were conducted using a semi-structured interview guide with open-ended questions.</p><p><strong>Results: </strong>Three themes emerged: \"Struggling to navigate healthcare\", \"Restricting everyday life\", and \"Seeing the future as uncertain, yet hopeful\". These themes highlight women's frustration and challenges in navigating the healthcare system, their perception of a limited everyday life that must be adapted to what the body can handle, uncertainty about the future, and hope of good health and better care.</p><p><strong>Conclusions: </strong>LAM avulsion can substantially impact women's quality of life. It is a hidden birth injury that needs attention. The results indicate many areas for improvement in healthcare, such as the value of confirmatory diagnosis and care that addresses the woman's overall situation.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"336"},"PeriodicalIF":2.4,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12232683/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Navigating treatment options: a qualitative study exploring Australian women's decision-making experiences and satisfaction with treatment of heavy menstrual bleeding.","authors":"Jennifer Ramsay, Matilda Riek, Bec Jenkinson, Tessa Copp, Joan Carlini, Jenny Doust","doi":"10.1186/s12905-025-03884-z","DOIUrl":"10.1186/s12905-025-03884-z","url":null,"abstract":"<p><strong>Background: </strong>A wide range of management options exist for heavy menstrual bleeding (HMB). Australian clinical standards emphasise the need for shared decision-making to ensure women receive comprehensive, reliable information about their options. However, the high variation in the usage of treatments, such as hysterectomy and endometrial ablation, across Australia suggests inconsistent access to quality care. This study aims to gain insights into Australian women's perceptions of current practices, their experiences of HMB care and treatment decision-making.</p><p><strong>Methods: </strong>A qualitative study using semi-structured interviews with Australian women who sought treatment for HMB within the past two years. Women were recruited via social media advertising. The interviews took place online between July and September 2024. Women were asked about (1) their experiences with HMB, (2) their interactions with clinicians (3) experiences of shared decision making and (4) what other resources they consulted in their treatment decision-making. Transcribed audio recordings were analysed thematically using Framework analysis.</p><p><strong>Results: </strong>Twenty-four participants between the ages of 35 and 55 were interviewed. Five main themes emerged: \"Why Women Seek Treatment\", \"Efforts and Obstacles in Securing Quality Care\", \"Women's Perceptions of Their Treatment Options\", \"The Role of Clinicians in Treatment Decision-making\" and \"Women consult various sources of information to make treatment decisions\".</p><p><strong>Conclusions: </strong>Australian women face significant barriers in accessing quality care and appropriate effective treatment for HMB. Women are often uncertain about what is considered a normal menstrual experience and receive inadequate information from clinicians. Women seek balanced, comprehensive information on all available treatment options and clear guidance on how treatment success is monitored. Tools that support shared decision-making have been identified as a potential method to improve HMB treatment journeys.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"327"},"PeriodicalIF":2.4,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12228148/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bladder Erosion and stone formation: a rare complication of laparoscopic cervical cerclage.","authors":"Shangjin Li, Shaojie Zhao, Yuanyuan Zhang, Bing Zhang","doi":"10.1186/s12905-025-03873-2","DOIUrl":"10.1186/s12905-025-03873-2","url":null,"abstract":"<p><strong>Background: </strong>Cervical cerclage represents a practical approach to addressing cervical insufficiency, but it also can bring serious complications. We present an extremely rare case of bladder erosion caused by the exposure of Mersilene tape after laparoscopic cervical cerclage for 3 years, which resulted in the formation of bladder calculi.</p><p><strong>Case presentation: </strong>The patient was a 35-year-old gravida 5 para 2 female with symptoms suggestive of urinary tract infections after 3 years of exposure to the Mersilene tape, including urinary frequency urinary urgency and painful micturition. The patient underwent B-ultrasound and cystoscopy showed bladder injury and bladder calculi. Then, the patient underwent laparoscopic pelvic adhesion release, removal of cervical cerclage, bladder calculi removal, and bladder repair under general anesthesia. During the follow-up, the patient has not experienced any symptoms related to the urinary and menstrual.</p><p><strong>Conclusion: </strong>This case report underscores the long-term potential risks associated with exposure to the Mersilene tape, including bladder injury and the formation of bladder stones.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"329"},"PeriodicalIF":2.4,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12228174/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal mental health improvement in ghana: role of green spaces exposure.","authors":"Sylvester Kumi Boakye, Leslie Danquah, Mary Antwi","doi":"10.1186/s12905-025-03886-x","DOIUrl":"10.1186/s12905-025-03886-x","url":null,"abstract":"<p><strong>Background: </strong>Green space exposure has been demonstrated to influence human physical and psychosocial health. We explored the relationship between self-reported green space exposure and maternal perceived stress, anxiety and depression.</p><p><strong>Methods: </strong>We interviewed 420 mothers using a hospital-based cross-sectional study design. We assessed maternal stress, anxiety and depression levels. Maternal self-reported green space exposure characteristics were identified using an interviewer-administered questionnaire. Multiple regression was used to identify the nature of relationships.</p><p><strong>Results: </strong>Higher perceived stress, anxiety, and depression were observed in 58.1%, 42.5%, and 58.9% of respondents, respectively. Perceived stress was significantly associated with maternal utilization of green spaces for leisure activities and physical exercise (β = -0.118, 95% CI [-0.118, 0.025]). Mothers' belief that spending time in green spaces positively impacts one's overall well-being was significantly associated with maternal anxiety (β = 0.117, 95% CI [0.049, 0.491]) and depression (β = 0.164, 95% CI [0.205, 0.769]).</p><p><strong>Conclusions: </strong>Our study findings suggest that green space exposure has the potential to attenuate stress, anxiety and depression among mothers. Policies relating to the establishment of green spaces and the maternal utilization of green spaces should be encouraged. Further studies should explore maternal health green space relationships using objective green space measurement.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"328"},"PeriodicalIF":2.4,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12228349/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Navigating healthcare in higher education for students with gynaecological pain: an exploratory survey.","authors":"Katie Paddock-Hall","doi":"10.1186/s12905-025-03882-1","DOIUrl":"10.1186/s12905-025-03882-1","url":null,"abstract":"","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"334"},"PeriodicalIF":2.4,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12229034/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The comparison of hematological inflammatory parameters before and after surgery in women with endometriosis: retrospective cohort study.","authors":"Onur Yavuz, Asli Akdoner, Kadir Alper Mankan, Ufuk Atlihan, Begum Ertan, Mehmet Guney","doi":"10.1186/s12905-025-03890-1","DOIUrl":"10.1186/s12905-025-03890-1","url":null,"abstract":"<p><strong>Background: </strong>Our aim was to compare preoperative and postoperative hematological inflammatory parameters in women with endometriosis.</p><p><strong>Methods: </strong>Data were collected from 411 patients who underwent laparoscopy surgery between January 2018 and December 2023. Postoperatively, the pathology reports indicated ovarian endometrioma in 201 patients (48.9%) and other benign ovarian cysts in 210 patients (51.1%). Subgroups were categorized as stage 1-2 endometriosis (n = 26, 6.3%), stage 3-4 endometriosis (n = 175, 42.6%) and benign ovarian cysts (n = 210, 51.1%). Hematological inflammatory markers and ultrasound findings were evaluated one week before the operation and six weeks after the operation and compared between groups. Statistical analysis was performed by SPSS version 26.0 Not normally distributed parameters were analyzed with the Kruskal Wallis, post hoc and Mann-Whitney U tests. Wilcoxon signed-rank test was used to determine changes before and after treatment. Chi-square test and Fisher precision test were used in the analysis of categorical data. Receiver operating characteristic analysis was performed to calculate the area under the curve, which indicates the average sensitivity of variables and its 95% confidence interval are reported for each assessed parameter. The appropriate cut-off value indicating the sum of the highest sensitivity and specificity was calculated for the most predictive variable. The p value considered statistically significant was < 0.05.</p><p><strong>Results: </strong>When comparing the postoperative and preoperative parameters of the main groups, it was determined that the NLR, MLR, and PLR values of both groups increased in the postoperative period, whereas the CA-125 value decreased. In a similar comparison within the subgroups, it was determined that NLR and PLR increased in all three groups in the postoperative period. MLR was found to increase in the stage 3-4 endometriosis and benign ovarian cyst groups. CA-125 decreased in the stage 3-4 endometriosis and benign ovarian cyst groups. RDW > 13.5, PLR > 123.4 and CA-125 > 35 were determined as the cut-off value to predict endometriosis.</p><p><strong>Conclusion: </strong>During the follow-ups, we revealed that CA-125 still maintains its effectiveness. There is a lack of existing literature that directly compares hematological inflammatory parameters before and after treatment for endometriosis.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"333"},"PeriodicalIF":2.4,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12229005/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}