Hacer Serin Gurel, Cem Dogan, Kübra Bozali, Memet Taskin Egici, Eray Metin Guler, Fisun Vural, Akin Dayan
{"title":"Investigation of copper and oxidative stress levels in oral contraceptive users.","authors":"Hacer Serin Gurel, Cem Dogan, Kübra Bozali, Memet Taskin Egici, Eray Metin Guler, Fisun Vural, Akin Dayan","doi":"10.1186/s12905-026-04519-7","DOIUrl":"https://doi.org/10.1186/s12905-026-04519-7","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to investigate the relationship between oxidative stress parameters [total oxidant status (TOS), total antioxidant status (TAS), thiol/disulfide homeostasis, ischemia-modified albumin (IMA)] and serum copper levels in women who use oral contraceptives (OCs) compared to those who do not.</p><p><strong>Methods: </strong>This single-center, prospective case-control study included a total of 154 women aged 18 to 45 years (72 OC users and 82 non-users) who presented to the gynecology outpatient clinic of a tertiary care training and research hospital. After obtaining written informed consent, demographic data and information regarding OC use were collected. Venous blood samples were drawn and serum samples were stored at -80 °C until analysis. Serum levels of TOS, TAS, total thiol, native thiol, disulfide, IMA and copper were measured. A p-value of < 0.05 was considered statistically significant.</p><p><strong>Results: </strong>In OC users, serum levels of copper, TOS, oxidative stress index (OSI), disulfide and IMA were significantly elevated, whereas TAS and native thiol levels were significantly reduced compared to non-users (p < 0.05). Serum copper levels showed a positive correlation with oxidative stress markers and a negative correlation with antioxidant capacity indicators.</p><p><strong>Conclusions: </strong>OC use is associated with increased serum copper levels, which in turn have a significant impact on oxidative stress biomarkers. These findings suggest that OC use elevates systemic oxidative stress while compromising antioxidant defense mechanisms. Moreover, elevated copper levels may independently contribute to oxidative stress regardless of OC use.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147833497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lauren Godier-McBard, Claire Hooks, Ellie Buxton, Louise Morgan, Abigail Adams, Matt Fossey
{"title":"Women veterans' experiences of veteran-specific support services: an international scoping review.","authors":"Lauren Godier-McBard, Claire Hooks, Ellie Buxton, Louise Morgan, Abigail Adams, Matt Fossey","doi":"10.1186/s12905-026-04512-0","DOIUrl":"https://doi.org/10.1186/s12905-026-04512-0","url":null,"abstract":"<p><strong>Background: </strong>The growing proportion of women in veteran communities internationally highlights a rising need for veteran support services tailored to their unique experiences. Despite this, support services remain predominantly designed for men, leading to underutilization and dissatisfaction among women veterans. This scoping review aimed to provide a comprehensive international review of the current state of knowledge regarding the experiences of women veterans in accessing and engaging with veteran-specific support services.</p><p><strong>Methods: </strong>This study followed the Joanna Briggs Institute scoping review methodology. Five databases were searched for papers published from 2000 onwards. Studies reporting on barriers and/or facilitators to access and experiences of engaging with veteran-specific support services reported by women veterans were included. There were no limitations on study methodology or country of origin, and all publications reporting primary research were included.</p><p><strong>Results: </strong>A total of 117 studies were included in the review. This research originated predominantly from the US (n = 109), with seven UK papers, and one Canadian. Eleven themes were identified across the literature, highlighting gendered barriers and facilitators of accessing veteran-specific support for women. Women veterans report feelings of discomfort, exclusion, and discrimination within veteran services, which are perceived as being set up and designed for men. Women report experiencing stigma in help-seeking compounded by a perception of feminine weakness experienced during military service. Some women didn't want to access services they saw as military-adjacent, due to gendered adverse experiences during military service, including discrimination, harassment, and sexual violence. A lack of identification with the term 'veteran' further hinders women's engagement with veteran-specific services. Enablers of access include care that is sensitive to women's needs, trauma-informed service user-provider relationships, and peer support.</p><p><strong>Conclusion: </strong>The reviewed evidence suggests women experience unique challenges and needs in accessing veteran-specific services. Support services should focus on developing care that is, culturally competent, trauma-informed and sensitive to the needs of women, to address gendered barriers to engagement. More research is needed to confirm these research findings outside of the US context, and incorporating an intersectional lens in future research will be essential for improving the support systems for women veterans internationally.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147811290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hong-Mei Wu, Ning Xu, Yuan-Hong Li, Zhi-Gui Luo, Rui Xiong, Min Li, Meng-Xi Li
{"title":"Single-port laparoscopic lateral suspension with total versus subtotal hysterectomy for pelvic organ prolapse: a prospective comparative study.","authors":"Hong-Mei Wu, Ning Xu, Yuan-Hong Li, Zhi-Gui Luo, Rui Xiong, Min Li, Meng-Xi Li","doi":"10.1186/s12905-026-04515-x","DOIUrl":"https://doi.org/10.1186/s12905-026-04515-x","url":null,"abstract":"<p><strong>Background: </strong>Laparoscopic lateral suspension (LLS) is an effective mesh-based repair for pelvic organ prolapse (POP), but the optimal concomitant hysterectomy strategy - total (TH) versus subtotal (STH) - remains undefined. We compared anatomic outcomes, patient-reported outcomes, and complication profiles of LLS combined with TH (LLSHR) versus LLS combined with STH (LLSHE) in a prospective cohort of women who made an informed choice between the two procedures.</p><p><strong>Methods: </strong>In this prospective comparative study conducted at Chengdu Integrated TCM & Western Medicine Hospital between October 2021 and October 2024, 82 women with symptomatic POP-Q stage II or III uterovaginal prolapse were counseled regarding both hysterectomy options and self-selected into the LLSHR group (n = 41) or the LLSHE group (n = 41). The study was approved by the institutional review board (IRB 2021.XJS.019) and retrospectively registered in the Chinese Clinical Trial Registry (ChiCTR2600118158). Primary outcomes were POP-Q point C and PISQ-12 score at 12 months. Secondary outcomes included POP-Q points Ba and Bp, PFDI-20, PFIQ-7, operative parameters, and mesh-related complications through 24 months.</p><p><strong>Results: </strong>All 82 participants completed surgery as planned. At 12 months, point C was significantly more negative in the LLSHE group than in the LLSHR group (- 5.1 ± 0.5 cm vs. -4.5 ± 0.6 cm; P < 0.001), indicating superior apical support with cervical preservation. The PISQ-12 score at 12 months was significantly higher (better) in the LLSHE group (37.5 [IQR 33.0-42.5] vs. 31.0 [27.0-34.0]; P < 0.001). PFDI-20 and PFIQ-7 improved substantially in both groups with no between-group difference at any time point (all P > 0.05). At 24 months, point C remained significantly more negative in the LLSHE group (- 4.8 ± 0.5 vs. -4.4 ± 0.6; P = 0.004), and the PISQ-12 advantage of LLSHE persisted (37.0 [34.0-43.0] vs. 31.5 [26.8-39.0]; P = 0.005). Mesh exposure was observed in 3 patients (9.4%) in the LLSHR group and none in the LLSHE group (P = 0.226). Operative time was significantly shorter in the LLSHE group (149.0 [143.0-165.0] min vs. 171.0 [150.0-186.0] min; P = 0.002).</p><p><strong>Conclusions: </strong>In women undergoing LLS for POP, STH was associated with superior apical support and better sexual function at both 12 and 24 months, with shorter operative time and a numerically lower rate of mesh exposure compared with TH. Given the non-randomized design, these findings should be interpreted as hypothesis-generating. Prospective randomized trials are warranted to confirm these associations.</p><p><strong>Trial registration: </strong>ChiCTR2600118158; registered February 2, 2026, retrospectively registered.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147811227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Qin Xie, Yanan Zhu, Bo Chen, Yajun Zhang, Meng Zhao, Yanli Lan, Xiaozhen Quan, Xuezhou Yang
{"title":"Association of sleep duration and quality with age at natural menopause: results from NHANES 2005-2018.","authors":"Qin Xie, Yanan Zhu, Bo Chen, Yajun Zhang, Meng Zhao, Yanli Lan, Xiaozhen Quan, Xuezhou Yang","doi":"10.1186/s12905-026-04508-w","DOIUrl":"https://doi.org/10.1186/s12905-026-04508-w","url":null,"abstract":"<p><strong>Background: </strong>While sleep is closely related to menopause, existing research has primarily focused on the impact of menopause on sleep, leaving the influence of sleep patterns on the timing of menopause largely unexplored. This study aimed to investigate the associations of sleep duration and quality with age at natural menopause.</p><p><strong>Methods: </strong>This study included women with complete data on sleep patterns and natural menopausal age from the National Health and Nutrition Examination Survey (NHANES) cycles 2005-2018. Logistic and linear regression models, progressively adjusted for demographic, lifestyle, and health-related covariates, were used to examine the relationships of sleep duration and quality with menopausal age, analyzed both as categorical (early/late menopause) and continuous variables. Restricted cubic splines were applied to assess nonlinear associations. Subgroup analyses and alternative menopausal age classifications were also performed.</p><p><strong>Results: </strong>A total of 2,157 women were included. Compared with medium sleep duration (7-9 hours), short sleep duration (< 7 hours) was associated with higher odds of early menopause in the initial model (OR = 1.41, 95% CI: 1.08-1.84, p = 0.01), but this association was attenuated in the fully adjusted model. Restricted cubic spline analysis revealed a nonlinear U-shaped association between sleep duration and early menopause (p for nonlinearity = 0.04), and an inverted U-shaped association with natural menopausal age (p for nonlinearity < 0.01), both peaking around 7.5 hours. Poor sleep quality remained significantly associated with early menopause after full adjustment (OR = 1.30, 95% CI: 1.01-1.66), but not with late menopause. In subgroup analyses, short sleep duration showed a stronger association with early menopause in women with BMI ≥ 28 and those without hormone use. Interestingly, poor sleep quality was positively associated with late menopause among women with ≥ 3 live births and no history of oral contraceptive use.</p><p><strong>Conclusions: </strong>Short sleep duration and poor sleep quality may be associated with early menopause, with evidence of nonlinear relationships and subgroup heterogeneity. In certain populations, poor sleep quality may also be linked to later menopause. These findings highlight the complex role of sleep in reproductive aging, requiring prospective studies to clarify causal pathways.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147811260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Murat İbrahim Toplu, Hiba Bashir Hassan, Ismail Mohamoud Abdullahi, Burak Deniz Aydoğdu, Yağmur Özkan, Marian Ali Abdi, Erhan Aktürk
{"title":"Paraclitoral cystic lesions after female genital mutilation: a clinicopathologic evaluation from Mogadishu.","authors":"Murat İbrahim Toplu, Hiba Bashir Hassan, Ismail Mohamoud Abdullahi, Burak Deniz Aydoğdu, Yağmur Özkan, Marian Ali Abdi, Erhan Aktürk","doi":"10.1186/s12905-026-04510-2","DOIUrl":"https://doi.org/10.1186/s12905-026-04510-2","url":null,"abstract":"<p><strong>Background: </strong>Female genital mutilation/cutting (FGM/C) is associated with long-term gynecologic complications, including delayed paraclitoral cystic lesions. However, the clinicopathologic spectrum and postoperative outcomes of these lesions remain insufficiently characterized, particularly in high-prevalence settings.</p><p><strong>Methods: </strong>This single-center retrospective clinicopathologic study included women with a history of FGM/C who underwent surgical excision of paraclitoral lesions between January 2017 and March 2025. Clinical presentation, surgical management, histopathological findings, and postoperative outcomes were analyzed. Comparative analyses were performed between epidermoid and non-epidermoid lesions.</p><p><strong>Results: </strong>A total of 146 patients were included. The mean age was 28.9 ± 13.2 years. The most common presenting symptom was pain (58.9%), and pain was present in 86.3% overall. Histopathology revealed predominantly epidermoid cysts (84.2%), followed by traumatic neuroma (8.9%) and other benign lesions. Parity was significantly associated with histopathologic subtype (p = 0.020), with non-epidermoid lesions more common in women with parity > 3. All patients underwent complete en bloc excision, and no intraoperative complications were documented in the available operative records. Among patients with available follow-up, postoperative pain improvement was documented in 89.7%, and no recurrence was documented among patients with available 6-month follow-up.</p><p><strong>Conclusion: </strong>Paraclitoral lesions following FGM/C are predominantly epidermoid cysts but may also include other pathologies, such as traumatic neuroma. Surgical excision was associated with favorable early documented outcomes among patients with available follow-up; however, interpretation of functional recovery and recurrence remains limited by nonstandardized retrospective outcome assessment and incomplete follow-up. These findings contribute additional clinicopathologic data to a limited evidence base and highlight the need for prospective studies with standardized follow-up.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147811219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rahbel Rahman-Tahir, Jane Prophet, Amna Tanweer Yazdani, Afton L Hassett, Rachel Gentile
{"title":"Unfiltered chronic pain: Insights from women with color through a virtual photovoice study.","authors":"Rahbel Rahman-Tahir, Jane Prophet, Amna Tanweer Yazdani, Afton L Hassett, Rachel Gentile","doi":"10.1186/s12905-026-04486-z","DOIUrl":"https://doi.org/10.1186/s12905-026-04486-z","url":null,"abstract":"<p><p>Photovoice was utilized with two groups of women of color in Ann Arbor, Michigan (n = 20) living with chronic pain to foster critical dialog about their experiences. The study aimed to explore and understand their lived experiences through collaborative engagement using a virtual Photovoice. The participants identified key themes, including pain, healing, self-care, overcoming obstacles, nature, and spirituality, which provided valuable insights into their journeys. Participant photographs and dialogues reveal how women of color navigate spaces where their pain is often misunderstood, while simultaneously alleviating pain and reclaiming dignity. To support holistic chronic pain management, systemic reforms must cover evidence-based complementary therapies, expand behavioral health access, fund community support groups, and mandate provider bias training co-designed by patients. These efforts should be guided by trauma-informed and interdisciplinary care models, supported by public awareness campaigns that validate the multidimensional reality of chronic pain and address structural barriers to wellness.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147811264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohamed N Farid, Bahaa M Hammad, Hany Saad, Asmaa Am Abdelfattah, Ahmed Mohamed Maged, Mohamed Rm Soliman
{"title":"The value of posterior colpotomy first technique on the vaginal length during total abdominal hysterectomy.","authors":"Mohamed N Farid, Bahaa M Hammad, Hany Saad, Asmaa Am Abdelfattah, Ahmed Mohamed Maged, Mohamed Rm Soliman","doi":"10.1186/s12905-026-04476-1","DOIUrl":"10.1186/s12905-026-04476-1","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the role of posterior colpotomy first technique in preserving vaginal length and support with total abdominal hysterectomy (TAH).</p><p><strong>Materials and methods: </strong>Eighty women candidate for TAH for benign lesion were randomly assigned to either classical technique (40 women) or posterior colpotomy first technique (40 women). The primary outcome parameter was the total vaginal length and shortening measured 3 months after the procedure.</p><p><strong>Results: </strong>The operative time was significantly longer in the posterior colpotomy group compared to classic group (106.28 ± 8.3 vs. 95.18 ± 18.35 min, P < 0.001). Total vaginal shortening was significantly lower in the posterior colpotomy group compared to classic group (0.99 ± 0.3 vs. 2.4 ± 0.8, P < 0.001). The number of women with postoperative dyspareunia was significantly lower in the posterior colpotomy group compared to classic group (4/40 (10%) vs. 8/40 (20%), P = 0.011). The female sexual function index score was significantly higher in the posterior colpotomy group compared to classic group (28.5 ± 2.5 vs. 24.19 ± 1.76, P = 0.038).</p><p><strong>Conclusion: </strong>The posterior colpotomy first technique is associated with less shortening of the total vaginal length, less occurrence of dyspareunia, and higher female sexual function index score compared to the classic approach for TAH.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13141387/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147811241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zheng Wang, Zhifeng Yan, Di Wu, Mingyang Wang, Yuanguang Meng, Mingxia Li
{"title":"Evaluation of endometrium by transvaginal ultrasound and baseline factors as a predictor for endometrial abnormalities in asymptomatic postmenopausal women.","authors":"Zheng Wang, Zhifeng Yan, Di Wu, Mingyang Wang, Yuanguang Meng, Mingxia Li","doi":"10.1186/s12905-026-04498-9","DOIUrl":"https://doi.org/10.1186/s12905-026-04498-9","url":null,"abstract":"<p><strong>Objective: </strong>The cut-off value of endometrial thickness (ET) in asymptomatic postmenopausal women, beyond which intervention is required, is still debated. This study aimed to provide a clinical decision support tool to guide the management of asymptomatic postmenopausal women with incidentally detected endometrial thickening.</p><p><strong>Methods: </strong>A retrospective observational study was conducted involving 280 asymptomatic postmenopausal women with ET > 5 mm who underwent hysteroscopy or dilation and curettage. Participants were stratified by menopausal duration and history of endocrine therapy for breast cancer. We analysed associations between ET, transvaginal ultrasound (TVUS) features, baseline characteristics and pathological outcomes. Based on univariate and multivariate analyses, we developed a prediction model to help predict endometrial lesions.</p><p><strong>Results: </strong>The pathological negativity rate was 35.36% among the whole cohort. We propose two candidate diagnostic thresholds for ET in asymptomatic postmenopausal women: a lower cut-off of 7 mm suggestive of any endometrial pathology (primary outcome), and a higher cut-off of 9.5 mm warranting suspicion for clinically significant pathology, including atypical endometrial hyperplasia (AEH) and endometrial cancer (EC) (secondary outcome). Our findings indicate a statistically significant difference in ET between healthy women within 5 years of menopause and those beyond 5 years. Nevertheless, no such significant disparity was observed in women with endometrial lesions. No significant difference was observed in ET between the overall population and patients receiving postoperative endocrine therapy for breast cancer. Using the presence or absence of endometrial lesions as the outcome, a prediction model was established. The model incorporates age, height, TVUS vessel pattern, and echogenicity. It provides a more holistic risk assessment tool than relying on a single millimetre measurement.</p><p><strong>Conclusion: </strong>Adopting a 7 mm candidate cut-off for intervention could spare over one‑third of asymptomatic women from unnecessary invasive procedures. Risk assessment should integrate TVUS morphological features with clinical factors, not merely rely on a single ET measurement. External validation in diverse populations is required before clinical implementation.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147811274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effectiveness of community-based health education intervention on knowledge, attitudes, and controlling behaviors related to intimate partner violence in Hadiya Zone, Central Ethiopia: a cluster randomized controlled trial.","authors":"Zeleke Dutamo Agde, Lire Lemma Tirore, Hordofa Gutema Abdissa, Mulatu Abageda, Gizachew Beykaso Agafari, Jeanette H Magnus, Nega Assefa, Muluemebet Abera Wordofa","doi":"10.1186/s12905-026-04507-x","DOIUrl":"https://doi.org/10.1186/s12905-026-04507-x","url":null,"abstract":"<p><strong>Background: </strong>In Ethiopia, a substantial proportion of women experience physical, psychological, or sexual violence perpetrated by their husbands or intimate partners. There is limited evidence on interventions aiming to improve awareness, alter attitudes, and control behavior related to IPV in Ethiopia. Therefore, this study aimed to evaluate the effectiveness of community-based health education (CBHE) targeting couples on knowledge, attitudes, and controlling behavior among women in Hadiya zone, central Ethiopia.</p><p><strong>Methods: </strong>A community-based, parallel-group, two-arm cluster randomized controlled trial design was employed to evaluate the effect of a CBHE intervention on knowledge, attitude, and controlling behavior related to IPV in Hadiya zone, central Ethiopia. A total of 432 women (216 in the intervention groups and 216 in the control groups) were involved in the study. The intervention was provided for couples over a period of six consecutive months. Generalized Estimating Equation (GEE) and difference-in-difference analysis were conducted to evaluate the effectiveness of the intervention on the outcomes.</p><p><strong>Results: </strong>About 94.4% of the mothers in the intervention groups and 95% of the women in the control groups were available for intention-to-treat analysis at the end of the intervention. Women in the intervention groups were about 5 times more likely to have good knowledge of IPV than those in the control groups (AOR = 4.8; 95% CI 2.9-7.9). Mothers in the intervention were 70% less likely to have a supportive attitude towards wife-beating compared to mothers in the control group (AOR = 0.3; 95% CI 0.2, 0.5). Likewise, mothers in the intervention groups were 60% less likely to justify controlling behavior from their husbands compared to those in the control groups (AOR = 0.4; 95% CI 0.3, 0.7).</p><p><strong>Conclusions: </strong>This study highlights that CBHE intervention led to a significant improvement in participants' knowledge of IPV against women. It also resulted in a marked reduction in the acceptance of wife-beating and justification of controlling behaviors. These findings provide strong evidence to support the broader scale-up of this intervention.</p><p><strong>Trial registration: </strong>This trial was recorded in the ClinicalTrials.gov registry with the identifier NCT05856214 on May 4, 2023.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147811310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hysteroscopic myomectomy for FIGO type 3 uterine fibroids with diameter not less than 5 cm: a retrospective, single-center study of eighteen cases.","authors":"Yuli Liu, Wei Wu, Jing Jin, Qian Zou, Qi Xing, Jingyu Wang, Wei Cao, Xin Du","doi":"10.1186/s12905-026-04448-5","DOIUrl":"https://doi.org/10.1186/s12905-026-04448-5","url":null,"abstract":"<p><strong>Background: </strong>Hysteroscopic myomectomy is a preferred treatment for women requiring future fertility. While it was difficult to manage large submucosal fibroids or deep intramural invasion myomas with hysteroscopic approaches. We conducted this study to explore the feasibility of hysteroscopic removal of large sized (≥ 5 cm) FIGO type 3 fibroids with deep intramural invasion that are difficult to manage with one-step hysteroscopy by \"downgrading\" technique.</p><p><strong>Methods: </strong>This retrospective study included of hysteroscopic myomectomy from February 2023 to September 2025 in an academic university hospital. The removal of large type 3 myomas was typically not less than 5 cm in maximum diameter. The clinical characteristics, details of the surgery and postoperative follow-up were collected for retrospective analysis.</p><p><strong>Results: </strong>A total of eighteen patients were included. The primary maximum diameter of fibroids ranges from 5 to 9.5 cm (median size was 6.5 cm) and ten of them was 6 cm or larger. 77.8% cases scored above 6 according to the classification of the STEPW classifications. Mean hysteroscopic operating time was 41.7 min. The perfusion fluid deficit was between 300 and 2,500 mL. The lowest blood potassium levels ranged from 2.11 to 3.82 mmol/ml. The One-step Hysteroscopic resection was performed in sixteen cases, 88.9% of patients. One case had successfully removed the residual fibroid through another hysteroscopic surgery six weeks after surgery, and another patient refused to receive a reoperation. All patients exhibited stable vital signs intraoperatively and postoperatively. The menstruation was recovered in all patients after the procedure. After 3 to 34 months of follow-up, there was no evidence of the recurrence in all but one patient who lost to follow-up at 1 year postoperatively. Notably, three patient achieved pregnancy spontaneously and two of them successfully delivered a healthy baby.</p><p><strong>Conclusions: </strong>Hysteroscopic resection with \"downgrading\" technique is a potential alternative approach for women with large (≥ 5 cm) FIGO type 3 fibroids. However, careful execution in a proficient hysteroscopic center is essential.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147811239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}