BMC Women's Health最新文献

{"title":"Patients' knowledge of and experience with Enhanced Recovery After Surgery (ERAS)-guided surgery: a qualitative study.","authors":"Seremi Ibadin, Benny Rana, Christine Smith, Gregg Nelson, Khara M Sauro","doi":"10.1186/s12905-026-04489-w","DOIUrl":"https://doi.org/10.1186/s12905-026-04489-w","url":null,"abstract":"<p><strong>Background: </strong>Implementing Enhanced Recovery After Surgery (ERAS) guidelines can improve post-operative outcomes and recovery. Patient partnership in care is a core tenet of ERAS, but there is little evidence exploring patients' perceived knowledge of and experience with ERAS guideline recommended care. The objective is to understand patients' knowledge of and experience with Enhanced Recovery After Surgery (ERAS)-guided surgeries.</p><p><strong>Methods: </strong>Using an interpretive descriptive approach, one-on-one interviews were conducted with patients who had undergone an ERAS-guided surgery in Alberta, Canada. The semi-structure interviews were facilitated by a trained qualitative researcher. The audio recordings were transcribed verbatim and were analyzed using framework analysis.</p><p><strong>Results: </strong>Seventeen interviews were conducted among females with a mean age of 59.1 years, who mostly had gynecologic or breast surgery. Knowledge of ERAS guidelines was minimal, but when probed about the ERAS care elements many patients expressed receiving ERAS compliant care. Four main themes emerged from the data: (1) patient awareness and education about ERAS guidelines, (2) patient experience with ERAS elements, (3) perception of the quality of care, and (4) patient informed strategies for improving surgical care.</p><p><strong>Conclusions: </strong>This study identified an opportunity to improve awareness of ERAS guidelines and ERAS recommended care. Patients expressed a desire to be better informed about the processes of care and to be more active members of the care team.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147811300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The characterization of patients with premature ovarian failure, endometriosis, and polycystic ovary syndrome in women attending comprehensive health centers in Urmia, Iran.","authors":"Behrouz Fathi, Hojat Ghasemnejad-Berenji, Seyedeh Sona Hashemi, Sonia Sadeghpour, Arezoo Hosseini, Vahid Alinejad, Samira Firooziyan, Masoumeh Manafpour, Morteza Bagheri","doi":"10.1186/s12905-026-04368-4","DOIUrl":"https://doi.org/10.1186/s12905-026-04368-4","url":null,"abstract":"","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147762827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of extracorporeal shockwave therapy on pain and pelvic floor function in women with pelvic floor myofascial pain: a retrospective cohort analysis.","authors":"Ya-Chu Wu, Dah-Ching Ding","doi":"10.1186/s12905-026-04496-x","DOIUrl":"https://doi.org/10.1186/s12905-026-04496-x","url":null,"abstract":"","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147811302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pre-rupture diagnosis and conservative surgery for ovarian ectopic pregnancy hidden by an endometrioma, guided by the transvaginal ultrasound \"sliding organ sign\": a case report and literature review.","authors":"Shuangshuang Wei, Wenhua Liu, Suju Liu, Hao Chen","doi":"10.1186/s12905-026-04504-0","DOIUrl":"https://doi.org/10.1186/s12905-026-04504-0","url":null,"abstract":"<p><strong>Background: </strong>Ovarian ectopic pregnancy (OEP) is a rare and life-threatening condition that is typically diagnosed post-rupture. Its diagnosis and management become more complex when it is concurrent with ovarian endometrioma, as the latter may mask the clinical and radiological features of OEP.</p><p><strong>Case presentation: </strong>We report the case of a 28-year-old woman (gravida 2, para 1) who presented with 44 days of amenorrhoea and lower abdominal pain. Transvaginal ultrasound (TVS) revealed an empty uterus, a complex right adnexal mass containing a yolk sac (with synchronous movement with the ovary and a negative \"sliding organ sign\", raising a strong suspicion of ovarian ectopic pregnancy), and a separate \"ground-glass\" cystic lesion (consistent with an endometrioma). Corpus luteum blood flow signals were detected in the left ovary. The patient's preoperative haemoglobin concentration was 128 g/L. Diagnostic laparoscopy confirmed a right ovarian pregnancy co-existing with an ipsilateral endometrioma. Both lesions were excised laparoscopically while preserving the ovary. Haemostasis was achieved by primary suturing supplemented with minimal bipolar coagulation to preserve ovarian function. The patient recovered well; her postoperative haemoglobin concentration was 122 g/L, and her menses resumed at 6 weeks post-operatively, which confirmed preserved ovarian function.</p><p><strong>Conclusions: </strong>This case reaffirms a fundamental clinical principle: any reproductive-age woman with a positive pregnancy test, an empty uterus, and an adnexal mass should be presumed to have an ectopic pregnancy, prompting immediate surgical evaluation. In our patient, this principle alone mandated surgery. The transvaginal ultrasound findings (a yolk sac and a negative \"sliding organ sign\") did not change the need for surgery, but they provided critical preoperative localization of the gestational sac to the ovary. This allowed us to anticipate an ovarian pregnancy, obtain specific consent for ovary-conserving surgery, and plan a suture-dominant haemostatic strategy. To our knowledge, this is the first reported case of pre-rupture diagnosis of an ovarian ectopic pregnancy masked by an endometrioma using these sonographic signs. Clinicians must prioritize the clinical triad; when available, meticulous ultrasound adds precision for fertility preservation.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147811278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Absence of high-risk human papillomavirus in breast cancer tissues from young BRCA1/BRCA2-negative women.","authors":"Eren Kaya, Edis Kahraman, Akif Enes Arikan, Fatma Tokat, Cihan Uras, Serkan Erkanlı","doi":"10.1186/s12905-026-04494-z","DOIUrl":"https://doi.org/10.1186/s12905-026-04494-z","url":null,"abstract":"<p><strong>Background: </strong>Human papillomavirus (HPV) has been investigated as a potential risk factor in breast cancer, but the literature remains inconsistent. Although biological mechanisms involving HPV E6/E7 oncogene activity provide biological plausibility for viral involvement, reproducible evidence in breast tumors is lacking. This study aimed to determine whether high-risk HPV is detectable or transcriptionally active in breast cancer tissues from young women negative for BRCA1/BRCA2 mutations.</p><p><strong>Methods: </strong>This retrospective, single-center study included women younger than 50 years with confirmed BRCA1/BRCA2-negative breast cancer. Formalin-fixed, paraffin-embedded tumor specimens were analyzed for high-risk HPV DNA using a PCR-based assay targeting HPV-16, HPV-18, and pooled high-risk genotypes. A subset of tumors with sufficient residual FFPE material and laboratory acceptance for FFPE-based RNA testing also underwent high-risk HPV E6/E7 mRNA analysis to assess transcriptional activity.</p><p><strong>Results: </strong>Ninety women contributed 91 breast cancer specimens. Demographic, reproductive, and pathological features were consistent with typical early-onset breast cancer. High-risk HPV DNA was not detected in any tumor specimen. All mRNA analyses were also negative, indicating absence of transcriptionally active viral oncogene expression.</p><p><strong>Conclusions: </strong>High-risk HPV was neither detectable nor transcriptionally active in breast cancer tissues from young BRCA1/BRCA2-negative women. These findings do not support a role for high-risk HPV in breast carcinogenesis in this population.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147762684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perioperative inflammatory response as a determinant of post-myomectomy intrauterine adhesion formation.","authors":"Xiaoshu Wang, Fangxin Li, Wenzhu Zhang, Wan Zhong, Jian Shen","doi":"10.1186/s12905-026-04416-z","DOIUrl":"https://doi.org/10.1186/s12905-026-04416-z","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Intrauterine adhesions (IUAs), or Asherman's syndrome, are a common complication of intrauterine surgery (e.g. hysteroscopic myomectomy) that can lead to menstrual disturbances and infertility. Excessive postoperative inflammation is thought to drive adhesion formation, but the predictive value of specific inflammatory biomarkers remains unclear.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;We performed a prospective observational study of 150 women (age 19-45) undergoing hysteroscopic submucosal fibroid resection. Serum C-reactive protein (CRP), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) were measured at three timepoints: preoperatively, 48 h postoperatively, and 3 months postoperatively. IUAs were assessed at 12 weeks via second-look hysteroscopy and graded by American Fertility Society criteria.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Of 135 patients who completed follow-up, 40 (30.8%) developed IUAs (20 mild, 12 moderate, 8 severe). Baseline characteristics were similar between those who developed IUAs and those who did not, except that FIGO type II fibroids were more frequent in the IUA group (20.0% vs. 8.4%, p = 0.04). IL-6 and CRP levels rose markedly after surgery in patients who developed adhesions, whereas increases in the no-IUA group were modest. By 48 h postoperatively, mean IL-6 was ~ 7 pg/mL higher in the IUA group than in no-IUA (23.0 vs. 15.8 pg/mL, p &lt; 0.001), and CRP was ~ 2.4 mg/L higher (8.5 vs. 6.1 mg/L, p &lt; 0.001). These differences persisted at 3 months (IL-6 18.2 vs. 14.2 pg/mL; CRP 6.4 vs. 5.1 mg/L; both p &lt; 0.001), indicating a prolonged inflammatory response. TNF-α rose modestly postoperatively in both groups and was significantly higher in the IUA group at 48 h (13.0 vs. 10.0 pg/mL, p &lt; 0.001) and 3 months (11.5 vs. 9.4 pg/mL, p = 0.01). IL-6 showed the strongest correlation with adhesion severity (Spearman ρ ≈ 0.5, p &lt; 0.001) and was an independent predictor of moderate-to-severe IUA risk (adjusted odds ratio [OR] 1.25 per 1 pg/mL, 95% confidence interval [CI] 1.11-1.42). CRP was also an independent predictor (OR 1.32 per 1 mg/L, 95% CI 1.08-1.61, p = 0.006), whereas TNF-α did not retain significance in multivariate analysis. In a model adjusting for surgical factors (fibroid type, operative time), IL-6 and CRP remained significant predictors (adjusted OR 1.22, 95% CI 1.09-1.39 and OR 1.29, 95% CI 1.06-1.57, respectively). Women with type II fibroids had higher odds of developing moderate/severe adhesions (OR ~ 2.8, 95% CI 1.1-7.3). ROC analysis demonstrated that IL-6 had the highest discriminative ability for clinically significant IUAs (area under curve [AUC] ≈ 0.80), outperforming CRP (AUC ≈ 0.72) and TNF-α (AUC ≈ 0.65). At an optimal 48-hour IL-6 cutoff of ~ 20 pg/mL, sensitivity for predicting moderate/severe adhesions was ~ 81% and specificity ~ 74%, while a CRP cutoff of ~ 7 mg/L yielded ~ 75% sensitivity and 65% specificity.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Perioperative elevation","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147762758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and correlates of physical, emotional, sexual, and technology-facilitated gender-based violence among a national sample of adolescent and adult women living with HIV in Zambia.","authors":"Karl Peltzer, Supa Pengpid","doi":"10.1186/s12905-026-04491-2","DOIUrl":"https://doi.org/10.1186/s12905-026-04491-2","url":null,"abstract":"","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147762818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PCOS combined with obesity aggravates the metabolic and immune abnormality in females.","authors":"Mei-Ling Chen, Shu-Ping Zhang, Jie Yang, Peng-Fei Qin, Jia-Qi Liu, Ning Su, Yan-Li Sun, Lin Gu, Zhi-Xia Yang, Jie Chen, Xian-Zhe Gu, Ping Zhou, Dong Zhang, Qian Li","doi":"10.1186/s12905-026-04492-1","DOIUrl":"https://doi.org/10.1186/s12905-026-04492-1","url":null,"abstract":"","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147762812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dietary patterns, physical activity, and nutrient intake among infertile women in an Iranian setting: a cross-sectional study.","authors":"Zare Maryam, Nemati Ali, Anbari Maryam, Jabbarzadeh Ghandilou Tahereh, Mardi Afrouz, Shadman Atefeh","doi":"10.1186/s12905-026-04468-1","DOIUrl":"https://doi.org/10.1186/s12905-026-04468-1","url":null,"abstract":"","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147762747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term effects of ospemifene on densitometric and bone metabolism biomarkers in postmenopausal women reporting Vulvar and Vaginal Atrophy (VVA).","authors":"Silvia Maffei, Alessia Formica, Dario Corsini, Michela Franchini","doi":"10.1186/s12905-026-04474-3","DOIUrl":"https://doi.org/10.1186/s12905-026-04474-3","url":null,"abstract":"","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147762761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}