BMC Women's Health最新文献

{"title":"Stillbirth increase long-term health risks of diabetes, CVD, CVD mortality, and all-cause mortality.","authors":"Yi Shen, JiaLyu Huang, Yan Chen, Yang Zhao, Zhaochen Sun, Ping Sun, Kaihong Zeng, Ping Shuai, Yuping Liu, Lei Yuan, Xiangzhi Li, Zhengwei Wan","doi":"10.1186/s12905-025-03856-3","DOIUrl":"10.1186/s12905-025-03856-3","url":null,"abstract":"<p><strong>Background: </strong>Fewer studies on association of single stillbirth exposure with long-term health outcomes in women. In this study of cohort data from UK Biobank, we aim to explore the association of stillbirth with the risk of diabetes, cardiovascular disease (CVD), all-cause mortality, CVD mortality, ischemic heart disease (IHD), myocardial infarction (MI), heart failure (HF), and stroke.</p><p><strong>Methods: </strong>We initially included 502,366 participants aged 40-69 years. Multivariate Cox regressions were used to evaluate associations of stillbirths with diabetes, CVD, all-cause mortality, and CVD mortality utilizing hazard ratios (HRs) and 95% confidence intervals (CIs). Moreover, non-linear relationship between stillbirths and four main outcomes above was analyzed by restricted cubic spline (RCS) modeling. Additionally, subgroup analyses and interaction term were performed to explore impact of specific factors on associations of interest. Cumulative incidence rates were calculated to observe time-event changes in target outcomes.</p><p><strong>Results: </strong>Finally, 248,195 women were included to analyze with 15,128 diabetes cases, 17,834 CVD cases, 15,334 all-cause mortality cases, and 949 CVD mortality cases. Among women who experienced stillbirth, fully adjusted HRs (95% CI) were 1.12 (1.07-1.18) for diabetes, 1.13 (1.08-1.19) for CVD, 1.12 (1.06-1.19) for all-cause mortality, and 1.27 (1.11-1.46) for CVD mortality. No significant associations were observed between stillbirth and all-cause or CVD mortality among women with household income ≥ 31,000 £, or without a history of hypertension. When specific cardiovascular outcomes were considered, the number of stillbirth was significantly associated with increased risk of IHD (HR 1.14; 95% CI 1.08-1.20) and MI (HR 1.14; 95% CI 1.01-1.27), while associations with stroke (HR 1.10; 95% CI 0.99-1.21) and HF (HR 1.12; 95% CI 0.98-1.27) were not statistically significant. Results of RCS plots and cumulative incidence rates show that the risk and incidence rates of diabetes, CVD, all-cause mortality, as well as CVD mortality ovaerall rose with increasing number of stillbirths and time, respectively.</p><p><strong>Conclusion: </strong>Stillbirth was associated with increased risks of diabetes, CVD, ischemic heart disease, all-cause mortality, and CVD mortality. These associations varied by socioeconomic and clinical factors. Given the observational design, these findings represent associations rather than causal relationships. Further research is needed to clarify underlying mechanisms.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"316"},"PeriodicalIF":2.4,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12231295/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144564547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors associated with intimate partner violence among ever-partnered women in two Southern African countries: a multilevel analysis.","authors":"Ololade Julius Baruwa, Elizabeth Biney, Broline Sagini Asuma, Acheampong Yaw Amoateng","doi":"10.1186/s12905-025-03831-y","DOIUrl":"10.1186/s12905-025-03831-y","url":null,"abstract":"<p><strong>Background: </strong>Intimate partner violence (IPV) is a pervasive global health issue with severe physical, emotional, and social consequences for women. In Southern Africa, where IPV rates are high, understanding the factors contributing to IPV is crucial for developing effective interventions. This study examines the factors associated with IPV among ever-partnered women in Malawi and South Africa, two countries with differing socioeconomic contexts but similarly high IPV prevalence.</p><p><strong>Method: </strong>Data from the 2016 Demographic and Health Survey (DHS) was used, including 7,760 ever-partnered women aged 15-49 from Malawi and South Africa. IPV was defined as lifetime physical, sexual, or emotional violence by a current or former partner and measured as a binary variable (yes/no). The independent variables included age, education, employment, place of residence, wealth status, partner alcohol use, autonomy, inequitable gender attitudes, and IPV history. A generalized linear mixed model (GLMM) was applied to identify IPV-related factors.</p><p><strong>Results: </strong>Findings revealed that women from Malawi were more likely to experience IPV than women from South Africa (aOR = 2.36, 95% CI = 1.97-2.83; p < 0.001). Women aged 25-29 years (aOR = 1.21, 95% CI = 1.03-1.42; p = 0.018) and 30-34 years (aOR = 1.30, 95% CI = 1.11-1.52; p = 0.001) were more likely to experience IPV than those aged 15-24 years. Women with higher education were less likely to experience IPV (aOR = 0.62, 95% CI = 0.44-0.88; p = 0.007). Employed women were more likely to experience IPV (aOR = 1.13, 95% CI = 1.01-1.26; p = 0.037). Women from the rich household wealth index (aOR = 0.81, 95% CI = 0.70-0.93; p = 0.003) were less likely to experience IPV than those in the poor wealth index. Women whose partners consumed alcohol (aOR = 2.98, 95% CI = 2.66-3.33; p < 0.001), with greater autonomy (aOR = 1.82 95% CI = 1.56-2.12; p < 0.001), inequitable gender attitudes (aOR = 1.82, 95% CI = 1.56-2.12; p < 0.001), and IPV history (aOR = 1.93, 95% CI = 1.72-2.18; p < 0.001) were more at increased risk of IPV.</p><p><strong>Conclusion: </strong>This study identifies key factors for designing targeted interventions to prevent IPV and improve women's well-being in Southern Africa.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"304"},"PeriodicalIF":2.4,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12231718/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144559188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Healthcare disparities in gynecological health services for women with disabilities: a cross-sectional study from Iraq.","authors":"Zainab Abdul Ameer Jaafar, Dina Akeel Salman, Reshed Zeki Obeid, Zaynab Alshaybi","doi":"10.1186/s12905-025-03861-6","DOIUrl":"10.1186/s12905-025-03861-6","url":null,"abstract":"","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"323"},"PeriodicalIF":2.4,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12231757/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144564539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rationality of FIGO 2018 IIIC cervical cancer according to local tumor and pelvic lymph node metastatic extent-a cohort study.","authors":"Na Li, Pinting Xu, Yuanjing Hu","doi":"10.1186/s12905-025-03846-5","DOIUrl":"10.1186/s12905-025-03846-5","url":null,"abstract":"<p><strong>Purpose: </strong>There is still controversy for FIGO 2018 stage IIIC. In order to better manage patients with stage IIIC. This study explored the prognostic performance of Stage IIIC patients according to the 2018 FIGO staging system.</p><p><strong>Methods: </strong>Cervical cancer patients who underwent radical surgery or chemo-radiotherapy at our institute between June 2011 and June 2021 were retrospectively enrolled. Patients before year 2018 were re-staged according to the 2018 FIGO staging principle. Survival outcome was analyzed by Kaplan-Meier curves and compared using Log-rank method. The best cut-off values for the number of positive lymph nodes and the positive lymph node ratio (LNR) were obtained using X-tile software V3.6.1. The Cox proportional hazard regression model was used for multi-variable analysis.</p><p><strong>Results: </strong>A total of 2553 cervical cancer patients were enrolled initially. Finally, 443 patients classified as 2018 FIGO stage III were included in the survival analysis.The 5-year disease-free survival (DFS) and 5-year overall survival (OS) of patients with stage IIIC2 were significantly poor than stage IIIA, IIIB and IIIC1, while IIIC1 patients had similar prognosis to IIIA/IIIB. For stage IIIC1 patients (n = 233), multivariate analysis showed that tumor size > 4 cm (DFS: HR 2.472, P < 0.001; OS: HR 2.368, P = 0.002) and poorly-differentiated histology (DFS: HR 2.158, P = 0.002; OS: HR 2.410, P = 0.002) were independent prognostic factors for reduced DFS and OS. In a subgroup analysis of IIIC1p women, tumor size > 4 cm (DFS: HR 2.658, P = 0.023; OS: HR 2.785, P = 0.039) and the number of positive pelvic lymph nodes(pLN) > 3 (DFS: HR 4.829, P < 0.001; OS: HR 5.614, P < 0.001) were found to be independent risk factors for reduced DFS and OS. Combining the local tumor size (TS) and pLN, patients with TS ≤ 4 cm + pLN ≤ 3 revealed significantly better 5-year DFS (89.2%) and 5-year OS (94.9%) than those with TS ≤ 4 cm + pLN > 3 and TS > 4 cm (P < 0.001). Moreover, stage IIIC1p patients with TS ≤ 4 cm + pLN ≤ 3 showed better DFS (P = 0.002) and OS (P = 0.001) than women with stage IIIA and IIIB.</p><p><strong>Conclusion: </strong>The survival outcomes for stage IIIC1 had similar prognosis for stage IIIA or IIIB in the current study. Patients with stage IIIC1p showed variable prognoses dependent on local tumor size and the extent of pelvic lymph node metastases. Therefore, the existing staging criteria might be further improved to provide better guidance for individualized treatment.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"308"},"PeriodicalIF":2.4,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12231735/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144564546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between lipid accumulation product and visceral adiposity index with endometriosis: evidence from NHANES 1999-2006.","authors":"Nan Ma, Yingying Hu, Yan Xu","doi":"10.1186/s12905-025-03862-5","DOIUrl":"10.1186/s12905-025-03862-5","url":null,"abstract":"<p><strong>Background: </strong>Obesity has been linked to chronic inflammation and insulin resistance and oxidative stress, which are all associated with the pathogenesis of endometriosis (EMs). This study aimed to investigate the associations between the emerging metabolic markers-lipid accumulation product (LAP) and visceral adiposity index (VAI)-with the EMs.</p><p><strong>Methods: </strong>This study utilized data from the National Health and Nutrition Examination Surveys (NHANES) 1999-2006. Weighted univariate and multivariate logistics regression models were conducted to explore the associations between LAP and VAI with EMs, with the results expressed as odds ratios (ORs) and 95% confidence intervals (CIs). Moreover, the subgroup analyses based on age, the history of pregnancy, chronic kidney disease (CKD), and female hormones use were further performed to verify whether theses associations remain robust.</p><p><strong>Results: </strong>Totally 5,188 eligible women were included, with a mean age of 37.19 ± 0.18 years. Among them, 359 (6.92%) had EMs. After adjusted all covariates, we observed both highest LAP and VAI are associated with EMs (LAP: OR = 1.56, 95%CI: 1.02-2.39; VAI: OR = 1.54, 95%CI: 1.09-2.18). Subgroup analyses shown that the associations between LAP and VAI with EMs were more significant among women aged ≥ 35 years, with the female hormones use, with the history of pregnancy, and without the history of CKD.</p><p><strong>Conclusion: </strong>We observed both high LAP and VAI were associated with EMs among reproductive women in the United States. However, further large-scale, well-designed, prospective cohort studies still need in the future to confirm these findings.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"307"},"PeriodicalIF":2.4,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12232157/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144559242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness and acceptability of two insertable device models for non-surgical management of obstetric fistula: protocol for a hybrid type I randomized crossover trial.","authors":"Nessa Ryan, Gabriel Y K Ganyaglo, Joonhee Park, Tracy Kuo Lin, Joanna Pozen, Avni Mittal, Alison M El Ayadi","doi":"10.1186/s12905-025-03823-y","DOIUrl":"10.1186/s12905-025-03823-y","url":null,"abstract":"<p><strong>Background: </strong>Obstetric fistula is a traumatic and stigmatized maternal morbidity often resulting in severe urinary and fecal incontinence. Women with fistula face multi-level barriers to surgical repair culminating in delays. Unfortunately, no acceptable temporizing measures to contain incontinence of urine exists. An insertable vaginal cup, alone or connected to a leg bag, has potential for improving incontinence management for women awaiting surgery or those whom surgery was unsuccessful, but effectiveness and acceptability are unknown.</p><p><strong>Methods: </strong>We describe a four-year clinical trial and nested qualitative study to examine the effectiveness and acceptability of an insertable vaginal cup to manage fistula urinary incontinence and understand fistula management costs. Two intervention models will be compared to a control: (1) vaginal cup ('cup'), and (2) vaginal cup attached via tubing to a leg-secured urine collection bag ('cup+'). Using a cross-over design, up to 100 participants will be block randomized to one of two sequences of leaking freely (no intervention), cup, and cup + at four fistula centers in Ghana and Kenya and observed for four days (400 total observations). Data will be captured through interviewer-administered survey, clinical exam and checklist. After clinic-based assessment, participants are individually randomized for cup or cup + for home use for up to 3 months and surveyed monthly. Effectiveness will be evaluated through quantitative comparison of urinary leakage (6 h and 24 h) and patient-reported quality of life (1-3 months) between cup, cup+, and leaking freely. Acceptability will be assessed quantitatively (1-3 months) and via in-depth interview among selected trial participants (n ~ 30) and potential implementers (n ~ 20).</p><p><strong>Discussion: </strong>This implementation study will inform the effectiveness and acceptability of the cup and cup + interventions as temporizing management strategies for fistula urinary incontinence. If the cup/cup + is effective and acceptable, this study will provide insight for future trials and cost-effective assessments in settings where fistula is prevalent. Expanding the evidence base on non-surgical temporizing management options will inform comprehensive fistula care through tertiary prevention and is likely to reduce vulnerability to stigma and improve economic opportunity and quality of life.</p><p><strong>Trial registrations and dates: </strong>ClinicalTrials.gov NCT05444504 (Date of registration: July 6, 2022). Pan African Clinical Trial Registry 202,209,466,217,416 (Date of registration: 9/22/2022). Ghana FDA Certificate FDA/CT/231 (Date of approval: 3/30/2023).</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"314"},"PeriodicalIF":2.4,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12231736/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144564582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of women's empowerment on lowering the number of children ever born in Bangladesh.","authors":"Shanjida Chowdhury, Md Aminul Haque","doi":"10.1186/s12905-025-03624-3","DOIUrl":"10.1186/s12905-025-03624-3","url":null,"abstract":"<p><strong>Introduction: </strong>Women's empowerment (WE) has become a central focus for development at a national and global level. There is a need for a comprehensive and updated assessment of the existing evidence on WE and the total number of children ever born (CEB). This paper addresses the association between different dimensions of WE and the total number of CEB among women aged 15-49 years in Dhaka, Bangladesh.</p><p><strong>Methods: </strong>This is a cross-sectional study. Using primary data, two binary and skewed regression models were applied to find the best-fitting model to investigate the association between different dimensions of women's empowerment and the total number of CEB.</p><p><strong>Results: </strong>Based on the Akaike Information Criterion (AIC) and the Bayesian Information Criterion (BIC) principles, the best-fit model was the binary logistic regression compared to other models. The study revealed that higher levels of women empowerment were associated with fewer CEB. Among the four dimensions-economic, psychological, household, and socio-cultural indices- psychological dimensions significantly influenced the number of CEB. Results also showed that age at first marriage, educational attainment of respondents, occupational level, wealth index, and use of contraceptives were found to be negatively associated with the number of CEB.</p><p><strong>Conclusion: </strong>The study found that an increase in WE was linked to a reduction in CEB. Other predictors for CEB were age at first marriage, women's educational attainment, working status, wealth index, and contraceptive use, which were all identified as factors associated with a lower number of children. Policymakers should focus on the dimension-specific and overall level of WE in reducing CEB.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"320"},"PeriodicalIF":2.4,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12232172/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144564581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gender-based violence and associated factors among women in Ethiopia: a systematic review and meta-analysis.","authors":"Berhanu Wale Yirdaw, Bimrew Bayuh Yimer","doi":"10.1186/s12905-025-03867-0","DOIUrl":"10.1186/s12905-025-03867-0","url":null,"abstract":"<p><strong>Background: </strong>Gender-based violence (GBV) is a significant public health and human rights issue globally. In Ethiopia, the true extent and associated factors of GBV among women remain inadequately synthesized. Thus, this systematic review and meta-analysis was aimed to estimate the pooled prevalence of GBV and identify its associated factors among women in Ethiopia.</p><p><strong>Methods: </strong>A comprehensive search of literatures was conducted using PubMed, Medline, HINARI, EMBASE, Web of Science, Scopus, and Google scholar from November 10, 2024 to November 30, 2024 following the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. Additional studies were searched using a reference of identified articles. Studies reporting the prevalence of GBV and associated factors among women in Ethiopia were included. Data were extracted using a standardized form and the quality of included studies was assessed using the Newcastle-Ottawa Scale. Inspection of the Funnel plot and Egger's test were used to evaluate the evidence of publication bias. The heterogeneity of the included studies was evaluated using Cochrane Q and I2 test. A random effects meta-analysis was computed to determine the pooled estimate of gender-based violence using STATA 17.</p><p><strong>Results: </strong>A total of 19 studies with 23,787 study participants were included in this review. The meta-analysis showed that the pooled prevalence of gender-based violence among women is 51.34% (95% CI: 44.48-58.19). Factors significantly associated with GBV included monthly pocket money received from their parents, urban residence, experience of sexual intercourse, young age, alcohol consumption, being single in marital status, tight family control and number of sexual partners.</p><p><strong>Conclusion: </strong>The prevalence of gender-based violence among women is found to be high, which is a significant concern. Identified associated factors highlight potential areas for targeted interventions and prevention strategies. Further research is needed to understand the complex interplay of these factors and evaluate the effectiveness of interventions.</p><p><strong>Prospero registration number: </strong>CRD42024619618.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"312"},"PeriodicalIF":2.4,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12231912/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144564538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of physical therapy on pain, disability and quality of life in women with lumbopelvic pain in postpartum period: a systematic review with evidence gap map and meta-analysis.","authors":"Fatih Özyurt, Esra Üzelpasacı, Abdulhamit Tayfur, Türkan Akbayrak","doi":"10.1186/s12905-025-03881-2","DOIUrl":"10.1186/s12905-025-03881-2","url":null,"abstract":"","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"318"},"PeriodicalIF":2.4,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12231622/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144564583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hemorrhagic ascites in endometriosis: a case series and clinical implications.","authors":"Elham Askary, Nahideh Afshar Zakariya, Zahra Parsaiyan, Saeed Alborzi, Tahereh Poordast","doi":"10.1186/s12905-025-03864-3","DOIUrl":"10.1186/s12905-025-03864-3","url":null,"abstract":"<p><strong>Background: </strong>Hemorrhagic ascites is a rare clinical manifestation of endometriosis, often misdiagnosed due to its resemblance to malignancy. This study aims to highlight diagnostic and management challenges by presenting three cases.</p><p><strong>Case presentation: </strong>Three nulliparous women presented with abdominal distension, pelvic pain, and large-volume bloody ascites. One had concurrent right-sided hemorrhagic pleural effusions. Imaging studies showed deep infiltrating endometriosis (DIE) without ovarian endometriomas in two patients. Laparoscopic surgery confirmed extensive endometriosis with 2-4 L of bloody ascitic fluid. Histopathological examination excluded malignancy and confirmed endometriosis. Postoperative medical therapy included hormonal suppression.</p><p><strong>Conclusion: </strong>Bloody ascites is an uncommon but important presentation of severe endometriosis. These cases highlight the importance of considering endometriosis in the differential diagnosis of bloody ascites, particularly in reproductive-aged women. Surgical diagnosis and histopathologic confirmation are essential to rule out malignancy. A multidisciplinary approach and individualized fertility planning are crucial in managing these complex cases.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"315"},"PeriodicalIF":2.4,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12232111/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144564540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}