{"title":"Working ability, Location, Intensity, Days of Pain, Dysmenorrhea (WaLIDD): cross-cultural adaptation, reliability, and validity of the Turkish version.","authors":"Halime Arikan, Erkan Erol","doi":"10.1186/s12905-025-03673-8","DOIUrl":"10.1186/s12905-025-03673-8","url":null,"abstract":"<p><strong>Background: </strong>Dysmenorrhea is a gynecological condition that causes painful menstrual cramps in the uterus, most commonly seen in women of reproductive age. The aim was to perform the reliability and validity of the Turkish Working Ability, Location, Intensity, Days of Pain, Dysmenorrhea (WaLIDD) score for evaluating individuals with dysmenorrhea. The evaluation of the reliability and validity of the Turkish version of the WaLIDD tool in the Turkish population is essential to ensure its accuracy, consistency, and cultural relevance in assessing the impact of dysmenorrhea.</p><p><strong>Methods: </strong>Cross-sectional, psychometric questionnaire research. 113 individuals with dysmenorrhea were included in the study. The reliability of the WaLIDD was evaluated using internal consistency and test-retest analyses, while its validity (both convergent and divergent) was assessed through correlation analysis. For correlation analysis WaLIDD, Premenstrual Syndrome Impact Questionnaire (PMS-IQ), Pain Disability Index (PDI), and Big Five Inventory-10 (BFI-10) were used.</p><p><strong>Results: </strong>The reliability analysis indicated that the questionnaire demonstrated an internal consistency value of 0.875 and an intraclass correlation coefficient (ICC) value of 0.778. Pearson correlation analysis indicated that the WaLIDD had a very well correlation with the PMS-IQ (0.726) and well correlation with the PDI (0.413). WaLIDD had a negligible correlation with the BFI-10 (0.088). There were no floor or ceiling effects observed in the Turkish version of the WaLIDD.</p><p><strong>Conclusions: </strong>WaLIDD was found to be a well-structured, valid, and reliable instrument that can be used to evaluate women with dysmenorrhea. The Turkish version of WaLIDD can be used in Turkish women in clinical practices and research.</p><p><strong>Trial registration: </strong>This study was registered in ClinicalTrials.gov (NCT05829512).</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"133"},"PeriodicalIF":2.4,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11929168/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The life experiences of Chinese women after late-life remarriage.","authors":"Qiong Li, Jianyuan Huang, Jiayun Liu, Pei Zhao","doi":"10.1186/s12905-025-03665-8","DOIUrl":"10.1186/s12905-025-03665-8","url":null,"abstract":"<p><strong>Background: </strong>Although late-life remarriage is not a rare phenomenon, it remains a controversial topic in China. Late-life remarriage involves many challenges and crises, especially for elderly women, who are often in weaker positions in remarriage relationships and face more difficulties. Currently, research on the life experiences of Chinese women after late-life remarriage is still limited. The purpose of this study is to explore and describe the life experiences of Chinese women who remarried later in life and to explore and describe their feelings about these experiences.</p><p><strong>Methods: </strong>A phenomenological qualitative research design involving in-depth semistructured interviews was selected. Data analysis was performed via Colaizzi's methodology.</p><p><strong>Results: </strong>Sixteen women participated in this study. Four themes and 8 subthemes emerged: (1) companionship and support attainment (daily companionship and economic support), (2) nanny-like treatment (undertaking most household chores and care work alone, suspected and guarded in terms of money), (3) degradation of social ties (decreased interaction with the original family, reduced contact with friends), and (4) concerns about the future (treatment costs after illness, housing issues after their new husband's death).</p><p><strong>Conclusion: </strong>Our results reveal the complexity and vulnerability of the life experiences of Chinese women after late-life remarriage, which are the result of a combination of sociocultural and structural factors and reflect the pressure and injustice that women endure in a patriarchal society. Moreover, the study reveals the inadequacy of basic medical insurance and basic pension insurance systems. The results of this study will not only help society at large better understand the life experiences of Chinese women in stepfamilies after late-life remarriage but also help to provide numerous important recommendations for professionals who provide support to stepfamilies, as well as for policymakers.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"131"},"PeriodicalIF":2.4,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11929301/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xinyuan Xie, Jinbin Song, Yue Wu, Mei Li, Wenfeng Guo, Shuang Li, Yanwu Li
{"title":"Correction: Study on gut microbiota and metabolomics in postmenopausal women.","authors":"Xinyuan Xie, Jinbin Song, Yue Wu, Mei Li, Wenfeng Guo, Shuang Li, Yanwu Li","doi":"10.1186/s12905-025-03676-5","DOIUrl":"10.1186/s12905-025-03676-5","url":null,"abstract":"","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"135"},"PeriodicalIF":2.4,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11929218/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhen-Dong Sun, Yan Zhang, Yu-Shen Yang, Chu-Yun Liu, Meng-Qin Pei, Wei-Dong Fu, He-Han He
{"title":"Construction and validation of a novel nomogram for prediction of lymph node metastasis in HER2-positive breast cancer: based on the optimal number of examined lymph nodes for accurate nodal staging.","authors":"Zhen-Dong Sun, Yan Zhang, Yu-Shen Yang, Chu-Yun Liu, Meng-Qin Pei, Wei-Dong Fu, He-Han He","doi":"10.1186/s12905-025-03663-w","DOIUrl":"10.1186/s12905-025-03663-w","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to construct and validate a novel nomogram for prediction of lymph node metastasis in HER2-positive breast cancer based on the optimal number of examined lymph nodes (ELNs) for accurate nodal staging.</p><p><strong>Methods: </strong>We included 4,040 patients diagnosed with HER2-positive breast cancer from the SEER database, randomly allocating them into training and validation cohorts in a 7:3 ratio. The optimal number of ELNs was identified via piecewise linear regression. The association of ELNs count with nodal migration was evaluated through Logistic Regression (LR) analysis and Random Forest (RF). The nomogram was constructed, and its' performance was evaluated by the receiver operating characteristic curves, calibration curve and Decision curve analysis curves.</p><p><strong>Results: </strong>The optimal number of ELNs was 13. LR and RF identified the optimal number of ELNs, radiotherapy status, chemotherapy status, T stage, and grade as independent predictive variables for node metastasis, which were used in the nomogram's construction. And the area under the curve values for the nomogram were 0.829 (95% confidence interval (CI): 0.813-0.845) and 0.833 (95% CI:0.808-0.858) in the training and test split respectively, surpassing those of the optimal number of ELNs (0.649, 95% CI: 0.631-0.667 and 0.676, 95% CI:0.648-0.704). Calibration plots exhibited low Brier scores (0.150 for training split, 0.145 for test split).</p><p><strong>Conclusion: </strong>This study developed a novel nomogram that integrates the optimal number of ELNs with other independent risk factors, facilitating individualized prediction of lymph node metastasis in patients with HER2-positive breast cancer.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"132"},"PeriodicalIF":2.4,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11929165/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analysis of clinical factors in endometriosis of the abdominal wall.","authors":"Qiucheng Jia, Huimin Tang, Wanying Chen, Weiwei Wei, Hong Zheng, Arong Liu, Jiming Chen","doi":"10.1186/s12905-025-03660-z","DOIUrl":"10.1186/s12905-025-03660-z","url":null,"abstract":"<p><strong>Background: </strong>The abdominal wall is one of the rare sites of endometriosis, and its clinical incidence is increasing year by year with the increasing cesarean section rate nowadays.</p><p><strong>Methods: </strong>A retrospective analysis was made on patients with abdominal wall endometriosis who attended Changzhou Second Hospital of Nanjing Medical University from January 2013 to December 2022. They were grouped by depth of infiltration of lesion and direction of incision, and the differences between the groups were compared.</p><p><strong>Results: </strong>A total of 228 patients aged 32.7 ± 4.2 with abdominal wall endometriosis were included in this study, including 210 cases with a history of abdominal transverse incision surgery, 16 cases with a history of vertical incision surgery, 1 case with a history of uterine fibroids surgery, and 1 case with primary abdominal endometriosis, and 178 cases with the primary symptom of cyclic pain. The patients were classified as solitary and complex ones according to the number of lesions. Both groups were statistically significant for BMI, number of caesarean sections, operation time, bleeding, and postoperative hospital stay (p < 0.05). According to the depth of infiltration, the patients were divided into fascial, rectus abdominis, and peritoneal types, with differences in latency time, CA125, maximum diameter of the lesion, operation time, bleeding, and postoperative hospital stay (p < 0.05). The direction of incision for caesarean section had no significant effect on the development of endometriosis in the abdominal wall or whether the lesions were multiple (p > 0.05). On imaging, magnetic resonance imaging was more accurate for lesion typing.</p><p><strong>Conclusion: </strong>AWE should be diagnosed early and treated surgically. The clinical manifestations of the same type are different, and CA125 testing and abdominal wall ultrasound can be used preoperatively for lesion typing. Nuclear magnetic resonance (NMR) may be used to improve preoperative preparations for difficult diagnosis or typing.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"134"},"PeriodicalIF":2.4,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11929196/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Severe menopausal symptoms and associated factors among post-menopausal women in Ambo town, West Shewa, Ethiopia: a cross-sectional study.","authors":"Galana Takele Namara, Binyam Seifu Woldeyes, Dereje Yadesa Irenso, Daniel Belema Fekene, Gizachew Abdissa Bulto, Musa Abduro Fata, Warkitu Sileshi Ensermu, Amare Tesfaye Yami","doi":"10.1186/s12905-025-03662-x","DOIUrl":"10.1186/s12905-025-03662-x","url":null,"abstract":"<p><strong>Background: </strong>Post-menopause is the permanent cessation of menstruation for 12 consecutive months at the age of 45 to 55 years. Post-menopausal women all over the world suffer from symptoms associated with menopause. Despite the fact that the population of menopausal women in Ethiopia is growing in parallel with their life expectancy, little is known about the severity and factors associated with menopausal symptoms among post-menopausal women. While previous studies in Ethiopia have primarily focused on the prevalence of severe menopausal symptoms, they have not thoroughly explored the underlying factors that may influence the severity of these symptoms. As a result, the specific factors that contribute to the severity of menopausal symptoms in Ethiopian women remain largely uninvestigated, leaving an important knowledge gap in this area. Therefore, this study was intended to assess severe menopausal symptoms and associated factors among post-menopausal women in Ambo town.</p><p><strong>Methods: </strong>A community-based cross-sectional study was conducted from August 3 to September 3, 2022, in Ambo town. The source population encompassed all post-menopausal women residing in Ambo Town. From this broader group, the study population was all post-menopausal women living in the three selected kebeles (the smallest administrative unit of Ethiopia). The sampling unit for this study was the household with post-menopausal women. A simple random sampling method was employed using computer-generated random numbers using the sampling frame taken from the conducted preliminary survey. Data were collected using a structured, interviewer-administered questionnaire. The data were entered using Epi Info version 7.1 and exported to SPSS version 25.0 for analysis. Bivariate analysis was used to examine individual relationships between independent variables and severe menopausal symptoms. Multivariable analysis then evaluated the combined impact of independent variables on severe menopausal symptoms while controlling for confounding factors, offering a comprehensive understanding of the factors that significantly influence symptom severity. Odds ratios with 95% Cl were estimated to identify the associated factors of the outcome variables, and statistical significance was affirmed at a p-value ≤ 0.05.</p><p><strong>Results: </strong>This study showed that one hundred thirty-three participants (30.4%), with a 95% CI (26.2%-35%), experienced severe menopausal symptoms during the past month. Age greater than 60 years [AOR = 3.2, 95% CI (1.3, 7.7)], not performing physical activity [AOR = 2.1, 95% CI (1.1, 4.4)], consuming alcohol [AOR = 1.8, 95% CI (1.1, 3.1), unfavorable attitude towards menopause [AOR = 1.8, 95% CI (1.1, 3.0)], and BMI > 29.9 kg/m<sup>2</sup> [AOR = 6.1, 95% CI (2.7, 14.2)] were associated with severe menopause symptoms.</p><p><strong>Conclusion and recommendation: </strong>According to this study, one in three postmenopausal wom","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"130"},"PeriodicalIF":2.4,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11929201/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143676822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between triglyceride levels and rheumatoid arthritis prevalence in women: a cross-sectional study of NHANES (1999-2018).","authors":"Chang-Mei Zeng, Jun He, Deng-Chao Wang, Hong Xie","doi":"10.1186/s12905-025-03645-y","DOIUrl":"10.1186/s12905-025-03645-y","url":null,"abstract":"<p><strong>Background: </strong>Rheumatoid arthritis (RA) is a chronic autoimmune disease with a higher prevalence in women. Triglycerides, key indicators of lipid metabolism, are linked to inflammation and metabolic disorders, both contributing to RA pathogenesis. However, the association between triglyceride levels and RA prevalence in women remains unclear. This study analyzes this association using NHANES (1999-2018) data to provide evidence for prevention and personalized intervention strategies.</p><p><strong>Methods: </strong>This study utilized data from the National Health and Nutrition Examination Survey (NHANES) spanning 1999 to 2018. It included 10,728 female participants, of whom 639 were diagnosed with RA. Triglyceride levels were categorized into four quartiles (Q1 to Q4), and multivariable logistic regression models were used to analyze the association between triglyceride levels and RA prevalence in women. Restricted cubic spline (RCS) analyses were performed to evaluate the potential nonlinear association between triglyceride levels and RA prevalence. Subgroup and interaction analyses were conducted to further investigate the association across different populations.</p><p><strong>Results: </strong>Among the 639 RA patients, higher triglyceride levels were significantly positively associated with RA prevalence in women. In the unadjusted model, elevated triglyceride levels were significantly associated with an increased RA prevalence (OR: 1.30, 95% CI: 1.04-1.61, P = 0.019). This association remained significant in the adjusted model, with the highest quartile showing a substantially higher risk compared to the lowest quartile (OR: 2.46, 95% CI: 1.22-4.95, P for trend = 0.04). RCS analyses indicated a linear association between triglyceride levels and RA prevalence (P for nonlinearity = 0.19). Subgroup analyses revealed consistent trends across various subgroups, with no significant interactions observed (all interaction P-values > 0.05).</p><p><strong>Conclusion: </strong>This study demonstrates a significant positive association between elevated triglyceride levels and RA prevalence in women, with a linear trend observed in this association. Future research should further investigate the role of triglyceride levels in the pathogenesis of RA and explore potential intervention pathways.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"129"},"PeriodicalIF":2.4,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11927311/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143676723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The prevalence of sexual dysfunction and its contributors among the women with multiple sclerosis.","authors":"Hossein Mozhdehipanah, Negin Sharifi, Ali Emami, Mojgan Agha Abbaslou, Monirsadat Mirzadeh","doi":"10.1186/s12905-025-03653-y","DOIUrl":"10.1186/s12905-025-03653-y","url":null,"abstract":"<p><strong>Background: </strong>Sexual dysfunction is one of the main complaints in women with Multiple Sclerosis (MS) and it affects different aspects of their lives. We aimed to determine the prevalence of sexual dysfunction among MS patients and address the main contributing factors.</p><p><strong>Methods: </strong>This cross-sectional study was performed on 100 women with MS who were referred to Bu-Ali Sina Hospital in 2020-2021. We completed a 19-item Female Sexual Function Index (FSFI) questionnaire for each participant. We also collected demographic data. Patients were categorized based on their disability index Expanded Disability Status Scale (EDSS) by a neurology specialist. Data were analyzed using SPSS 25 software. A significance level of less than 0.05 was considered.</p><p><strong>Results: </strong>The mean age of study participants was 37.4 ± 7.8 years. We observed a negative significant correlation between EDSS and FSFI score (r=-0.371, P-value = 0.001). The correlation between FSFI score and age (r= -0.371, P-value = 0.001), parity (r= -0.322, P-value = 0.001), and disease duration (r= -0.371, P-value < 0.001) was also statistically significant. The mean of FSFI in the patients with university graduation was 25.0 ± 5.3, while it was 22.2 ± 6.4 and 20.1 ± 8.0 in diploma and less than diploma groups, respectively (P-value < 0.05). In linear regression, age, parity, length of disease and education level (just less than diploma and university graduated) as independent variables had a significant relationship with FSFI score (P < 0.05).</p><p><strong>Conclusion: </strong>The prevalence of sexual dysfunction among Iranian women who were suffering from MS was pretty high. Older age groups, less educated, and more disabled patients were addressed as more at-risk groups of impaired sexual function.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"128"},"PeriodicalIF":2.4,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11927215/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143676825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effect of mindfulness-based nursing support on the psychosocial status of women receiving infertility treatment: a randomized controlled trial.","authors":"Özen İnam, İlkay Güngör Satılmış","doi":"10.1186/s12905-025-03659-6","DOIUrl":"10.1186/s12905-025-03659-6","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to evaluate the effect of mindfulness-based support on the psychosocial status of women undergoing infertility treatment.</p><p><strong>Method: </strong>The study was conducted with 34 women who were about to start in vitro fertilization (IVF) and met the inclusion criteria. Participants were randomly assigned to either the experimental group (n = 17) or the control group (n = 17) using random number sequences generated on \" http://www.random.org . This process accounted for potential participant loss and was implemented in the order of participation. When cases withdrew, new participants were assigned based on the random sequence. All participants were women over the age of 18, literate, and users of smartphones. The experimental group used the IVFmind mobile application, specially developed for this study to facilitate mindfulness practices for infertility treatment. Psychosocial status was assessed using the Mindfulness Attention Awareness Scale, Infertility Self-Efficacy Scale-Short Form, Infertility Adjustment Scale, and Depression Anxiety Stress Scale. Data were collected through pre-tests and post-tests, and statistical analyses were performed.</p><p><strong>Results: </strong>There were no significant differences between the experimental and control groups in terms of socio-demographic characteristics and infertility-related factors (p > 0.05). Mindfulness Attention Awareness Scale: No significant difference was found between groups in the pre-test scores (U = 120,000, p = 0.398). However, post-test scores of the experimental group were significantly higher than those of the control group (U = 0.000, p < 0.001). Infertility Self-Efficacy Scale-Short Form: No significant difference was found between groups in the pre-test scores (U = 125,500, p = 0.503). In the post-test, the experimental group scored significantly higher than the control group (U = 0.000, p < 0.001). Infertility Adjustment Scale: Pre-test scores showed no significant differences between the groups (U = 106,500, p = 0.184). In the post-test, the experimental group had significantly lower scores compared to the control group, indicating better adjustment (U = 3,000, p < 0.001). Depression Anxiety Stress Scale: There was no significant difference between the groups in the pre-test scores (U = 141,000, p = 0.904). However, post-test scores of the experimental group were significantly lower than those of the control group (U = 56,500, p = 0.002).</p><p><strong>Conclusions: </strong>The mindfulness-based mobile application positively impacted the psychosocial status of women undergoing infertility treatment, demonstrating significant improvements. The experimental group showed notable increases in mindfulness, self-efficacy, and adjustment levels, along with significant reductions in depression and anxiety. These results highlight the effectiveness of mindfulness-based interventions in addressing psychological challenges associate","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"127"},"PeriodicalIF":2.4,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924654/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143668761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence and genotype distribution of HPV infection among women in 2021-2023 in southern Iran: The rising trend of HPV infection among women.","authors":"Khadijeh Ahmadi, Rezvan Armat, Behzad Shahbazi, Elahe Sasani, Afrooz Azad, Zahra Gharibi, Hamed Gouklani","doi":"10.1186/s12905-025-03668-5","DOIUrl":"10.1186/s12905-025-03668-5","url":null,"abstract":"<p><strong>Background: </strong>Human papillomavirus (HPV) infection is the leading cause of genital disease. More information on the prevalence and distribution of genital HPV subtypes in the female population is needed to inform preventive strategies. Geographical, social, economic, and ethnic barriers in developing countries challenge the development of preventive measures for cervical cancer. For the first time, we sought to determine the prevalence of HPV infection among women referred to gynecologists in southern Iran.</p><p><strong>Methods: </strong>This cross-sectional study was conducted in Hormozgan, Iran from July 2021 to July 2023 on various cervical specimens from all outpatients referred to the Virology Laboratory of the Infectious and Tropical Diseases Research Center. HPV DNA was extracted from genital swabs of the study participants using the QIAamp DNA Extraction Kit. Genotyping was performed on 3960 cases using multiplex PCR and a microarray chip (Master Diagnóstica, Granada, Spain) to identify 18 high-risk (HR) and 18 low-risk (LR) HPV genotypes. Demographic data were statistically analyzed in relation to viral data.</p><p><strong>Results: </strong>Of 3960 cases, 1303 (32.90%) were HPV positive. HPV positive patients were younger than negative patients. The positive rate was higher in the age group 20 to 40 years (72%). Single HPV infection was the most common pattern, accounting for 52.57% of cases while double infection accounted for 21.18% of the positive cases. The most common HR-HPV subtypes in southern Iran were HPV 16, 52, 31, and 53 (12.58, 8.36, 6.60, and 6.44%, respectively). Also, the most common LR-HPV subtypes were HPV6, 42, 62.81, and 44.55 (14.58, 12.58, 8.36, and 8.05, respectively). A comparison of the prevalence of HPV infection showed an increase in cases (in 2022-2023 (36.05%) compared with that in 2021-2022 (29.92%)), a decrease in the age of infected women (41.50% for 2022-2023 and 42.05% for 2021-2022) and an increase in multi-genotypic cases (42.44% for 2022-2023 and 31.24% for 2021-2022).</p><p><strong>Conclusions: </strong>These observations highlight the need for a program to educate the young population of the community as well as the implementation of infection control measures against HPV infection, especially in the case of mass HPV vaccination of the general population.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"126"},"PeriodicalIF":2.4,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924696/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}