BMC Women's Health最新文献

{"title":"A multifaceted menstrual health intervention to improve psychosocial outcomes and menstrual practices among secondary schoolgirls in Northwest Tanzania: a pilot intervention study.","authors":"Philip Ayieko, Belen Torondel, Jenny Renju, Jennifer Rubli, Onike Mcharo, John R Luwayi, Katherine A Thomas, Giulia Greco, Saidi Kapiga, Elialilia S Okello","doi":"10.1186/s12905-025-03723-1","DOIUrl":"https://doi.org/10.1186/s12905-025-03723-1","url":null,"abstract":"<p><strong>Introduction: </strong>Schools provide an important opportunity to sustainably reach and improve menstrual experiences and outcomes among adolescent girls. This study examined changes in psychosocial outcomes and menstrual practices after a pilot menstrual health intervention in schools in Northwest Tanzania.</p><p><strong>Methods: </strong>We conducted a pre/post evaluation of a pilot menstrual health intervention in four schools in Mwanza region. The intervention included: (i) 10-hours comprehensive menstrual sexual and reproductive health (MSRH) education curriculum delivered over 5 days, (ii) distribution of menstrual management kits, (iii) improvement of school WASH facility guided by needs, and (iv) training on menstrual pain management strategies, supply of pain killers and training a specific teacher on dispensing. The primary outcome was measured using the Menstrual Practices Need Scale (MPNS). We assessed seven secondary outcomes: menstrual pain management practice; self-efficacy in managing menstruation; menstrual-related anxiety; self-reported urogenital infection symptoms; MSRH knowledge; participation in school during menstruation; and school climate score. We used linear (for MPNS, and school climate score), and logistic (for remaining secondary outcomes) random-effect regression models to examine changes in outcomes between baseline and endline.</p><p><strong>Results: </strong>A total of 486 schoolgirls (mean age 15.6 years [SD 1.3]) were recruited for the baseline survey; of these 396 participated in the endline survey. At 12-months follow up, menstrual experience improved for MPNS-36 subscales of transport and menstrual material needs, (mean difference (MD), 0.52; 95% CI 0.38-0.66), and menstrual material reuse needs, (MD 0.32; 0.14-0.50), while menstrual materials reuse insecurity did not change, (MD -0.08; -0.27-0.11). For the secondary outcomes, there was an increased use of analgesics for menstrual pain management, (OR 2.21; 95% CI 1.33-3.67); improved self-efficacy for managing menstruation, (OR 2.02; 1.35-3.04); MSRH knowledge, (OR 5.23; 3.25-8.39), participation in school (OR 2.80; 1.89-4.16) and reduced menstrual-related anxiety, (OR 0.38; 0.25-0.59). There was no evidence of change in self-reported urogenital symptoms, (OR 0.71; 0.49-1.01) or school climate, (MD 0.05; -0.19-0.28).</p><p><strong>Conclusion: </strong>The pilot intervention showed improvements in menstrual practices, psychosocial outcomes and school participation among schoolgirls but had no effect on school climate or self-reported urogenital symptoms. Stronger evidence from rigorously designed trials is needed to confirm the effectiveness of the intervention and scalability of these findings.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"190"},"PeriodicalIF":2.4,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12007168/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143980388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determinants of healthcare decision-making autonomy among Bangladeshi women: mixed-effect logistic regression analysis.","authors":"Rafsaniat Binte Mustafiz, Syed Sharaf Ahmed Chowdhury, Satyajit Kundu, Nurjahan Binte Munaf, Azaz Bin Sharif","doi":"10.1186/s12905-025-03666-7","DOIUrl":"https://doi.org/10.1186/s12905-025-03666-7","url":null,"abstract":"<p><strong>Background: </strong>Women's healthcare decision-making autonomy is observed to play a significant role in improving maternal and child health outcomes. However, there is a dearth of research that addressed this issue in the Bangladeshi context. Therefore, this study aimed to estimate the prevalence of healthcare decision-making autonomy and its determinants among Bangladeshi women.</p><p><strong>Methods: </strong>Data on 18,890 (weighted) women's healthcare autonomy were driven from the Bangladesh Demographic and Health Survey (BDHS) 2017-18. A multilevel (mixed-effect) logistic regression model was applied to explore the determinants of healthcare autonomy.</p><p><strong>Results: </strong>Overall weighted prevalence of healthcare autonomy was 76.5% (95% CI: 75.85-77.06). The odds of having healthcare autonomy were higher among women belonging to 25-34 years (aOR: 1.69, 95% CI: 1.52-1.87), and 35-49 years (aOR: 1.89, 95% CI: 1.65-2.17) age group, attaining secondary (aOR: 1.31, 95% CI: 1.14-1.50), and higher education (aOR: 1.61, 95% CI: 1.33-1.94), who were employed (aOR: 1.37, 95% CI: 1.26-1.50), who read newspaper/magazine at least once a week (aOR: 1.45, 95% CI: 1.13-1.84), having 1-2 (aOR: 1.91, 95% CI: 1.67-2.17), and 3 or more (aOR: 1.94, 95% CI: 1.65-2.27) living children, gave no birth in the last 3 years (aOR: 1.17, 95% CI: 1.06-1.29), and from urban areas (aOR: 1.43, 95% CI: 1.25-1.63).</p><p><strong>Conclusion: </strong>Around one-quarter of the women were not autonomous regarding their healthcare decision-making. So, it is necessary to implement strategies and policies that can enable and empower women in the healthcare aspects of their lives.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"192"},"PeriodicalIF":2.4,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12007339/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143981060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between meat consumption and polycystic ovary syndrome in Iranian women: a case-control study.","authors":"Mina Darand, Moloud Ghorbani, Akram Ghadiri-Anari, Vahid Arabi, Mahdieh Hosseinzadeh","doi":"10.1186/s12905-025-03695-2","DOIUrl":"https://doi.org/10.1186/s12905-025-03695-2","url":null,"abstract":"<p><strong>Background: </strong>In light of the observed association between nutritional factors and polycystic ovary syndrome (PCOS) in recent decades, the present study was conducted to investigate the association between the consumption of various types of meat and PCOS in Iranian women.</p><p><strong>Material and methods: </strong>This frequency-matched case-control study included 108 women with newly diagnosed PCOS and 108 age and body-mass-index-matched women without PCOS, as a control group, who were referred to the Yazd Diabetes Clinic and Khatam Clinic between January 2018 and March 2019. The validated 178-item food frequency questionnaire was used to assess the usual dietary intake. Logistic regression analysis was used to estimate the association between meat consumption and PCOS.</p><p><strong>Results: </strong>The findings of this study showed, the individuals in the third tertile of red meat intake, had higher odds of PCOS in the crude model (Odds Ratio (OR) = 4.29; 95% Confidence Interval (CI), 2.13-8.64; P-value = 0.001) compared with those in the first tertile. These results remained significant after adjustments for energy intake, marital status, physical activity, education, pregnancy history and chronic disease history (OR = 3.87; 95% CI, 1.78-8.40; P-value = 0.001). Higher consumption of red meat increased the risk of PCOS by 3.87 times. Furthermore, higher consumption of processed meats increased the risk of PCOS by 2.15 times (OR = 2.15; 95% CI, 1.05-4.39; P-value and trend = 0.035). We did not find an association between other types of meat consumption and PCOS.</p><p><strong>Conclusion: </strong>The results of the present study showed that a higher consumption of red and processed meat is associated with a higher risk of PCOS, whereas no significant correlation was found between the consumption of poultry, fish, and organ meat and PCOS. However, more studies are needed to support these findings in the future.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"189"},"PeriodicalIF":2.4,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12007253/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143978601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between gynecological cancers and female infertility: insights from bidirectional Mendelian randomization analysis.","authors":"Jifeng Li, Yifei Zeng, Dongxiao Zhang","doi":"10.1186/s12905-025-03729-9","DOIUrl":"https://doi.org/10.1186/s12905-025-03729-9","url":null,"abstract":"<p><strong>Purpose: </strong>In recent years, research interest in the potential link between female infertility (FI) and gynecological cancer (GC), including ovarian cancer (OC), endometrial cancer (EC), cervical cancer (CC), and breast cancer (BC), has grown, yet findings remain inconclusive. This study aims to explore the causal relationship between FI and GC using bidirectional two-sample Mendelian randomization (MR) analyses, thereby informing future strategies for FI and GC prevention.</p><p><strong>Methods: </strong>We utilized SNPs identified from genome-wide association studies (GWAS) on FI and GC. The inverse variance weighted (IVW) method served as the primary approach to assess the causal association between FI and GC. Additionally, five other MR methods-Weighted median, Weighted mode, MR-Egger, Simple mode, and Robust-Adjusted Profile Score-were employed to enhance result robustness and credibility.</p><p><strong>Results: </strong>In the forward MR analysis, our IVW results indicated no significant association between FI and GC (FI-BC: OR = 0.95, 95% CI: 0.83-1.09, P = 0.47, P-FDR = 0.775; FI-OC: OR = 1.01, 95% CI: 0.84-1.24, P = 0.789, P-FDR = 0.896; FI-CC: OR = 0.80, 95% CI: 0.61-1.06, P = 0.118, P-FDR = 0.775; FI-EC: OR = 1.07, 95% CI: 0.88-1.30, P = 0.490, P-FDR = 0.775).In the reverse MR analysis, we found a marginal association between BC and FI. However, after adjusting for multiple testing using the FDR method, no significant causal relationship was found between BC and FI, suggesting a marginal association (OR = 1.054, 95% CI: 1.001-1.108, P = 0.043, P-FDR = 0.331). For other cancers, no significant causal relationships were observed between OC, CC and EC with FI(OC-FI: OR = 1.043, 95% CI: 0.999-1.087, P = 0.051, P-FDR = 0.331;CC-FI: OR = 0.992, 95% CI: 0.956-1.028, P = 0.654, P-FDR = 0.836; EC-FI: OR = 1.006, 95% CI: 0.956-1.055, P = 0.809, P-FDR = 0.885).</p><p><strong>Conclusions: </strong>Our study found no significant causal relationship between FI and GC. However, a potential marginal association between BC and FI was observed. These findings underscore the need for further research to confirm this association and emphasize the importance of reproductive protection for young breast cancer patients to preserve fertility.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"191"},"PeriodicalIF":2.4,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12007144/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143962619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of pelvic position on ultrasonic measurement parameters of pelvic floor in postpartum women.","authors":"Yu Wang, Yan Zhuo, Min Liu, Jianqi Fang, Zongjie Weng","doi":"10.1186/s12905-025-03708-0","DOIUrl":"https://doi.org/10.1186/s12905-025-03708-0","url":null,"abstract":"<p><strong>Objective: </strong>To analyse the effect of pelvic position on ultrasonic measurement parameters of pelvic floor in postpartum women.</p><p><strong>Methods: </strong>This study included 132 postpartum participants who visited Fujian Maternity and Child Health Hospital from May 2020 to May 2024. All participants were assessed by medical professionals for general information and pelvic floor four dimensional ultrasound. Ultrasonic measurements were performed in three different positions of the pelvis (anterior pelvic tilt, posterior pelvic tilt, and neutral pelvic tilt) based on lithotomy position.</p><p><strong>Results: </strong>Our results indicated that the differences in the diagnosis of cystocele, uterine prolapse, perineal overactivity, and hiatal ballooning among the neutral position, anterior pelvic tilt, and posterior pelvic tilt were statistically significant (P<.001, P<.001, P<.001, and P<.001 respectively). The differences among neutral pelvic tilt, anterior pelvic tilt, and posterior pelvic tilt in hiatal area (during contraction), hiatal area (during rest), hiatal area (during valsalva), bladder neck descent, urethral rotation angle, cervical descent, rectal ampulla descent, hiatal area increase, and hiatal area decrease were statistically significant (P <.001, P <.001, P <.001, P <.001, P <.001, P <.001, P <.001, P <.001, and P <.001 respectively), with almost all the values of those parameters in posterior pelvic tilt the highest among three groups. The differences in cervical position (at rest), rectal ampulla position (at rest), and bladder neck position (during valsalva), cervical position (during valsalva), and rectal ampulla position (during valsalva) among neutral pelvic tilt, anterior pelvic tilt, and posterior pelvic tilt were statistically significant (P <.001, P =.035, P <.001, P <.001, and P <.001 respectively), with almost all the values of those parameters in posterior pelvic tilt the lowest among three groups.</p><p><strong>Conclusion: </strong>During the pelvic floor muscle contraction, the posterior pelvic tilt showed the most reduction of hiatal area compared to that in other positions. During Valsalva, not only the most increase of the hiatal area, but also the greatest bladder neck descent, cervical neck descent, and rectal ampulla descent were observed in the posterior pelvic tilt position.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"184"},"PeriodicalIF":2.4,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12001394/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Co-developing a digital mindfulness- and acceptance-based intervention for endometriosis management and care: a qualitative feasibility study.","authors":"Nina Maindal, Ulrik Bak Kirk, Karina Ejgaard Hansen","doi":"10.1186/s12905-025-03731-1","DOIUrl":"https://doi.org/10.1186/s12905-025-03731-1","url":null,"abstract":"<p><strong>Background: </strong>MY-ENDO (Mind Your ENDOmetriosis) is a mindfulness- and acceptance-based endometriosis self-management intervention aimed at teaching women with symptomatic endometriosis how to manage and reduce negative physical, psychological, and social consequences of endometriosis. This study aimed at involving women with endometriosis in the co-development process of a digital version of MY-ENDO to investigate their experiences with and attitudes toward the intervention.</p><p><strong>Methods: </strong>The study was designed as a qualitative feasibility study. The empirical material consisted of 35 interviews with seven women who self-reported a diagnosis with endometriosis, based on a semi-structured interview guide. Each participant completed the first four sessions of the intervention and was interviewed before the first and after each of the four sessions (five times in total) during participation. The study was based on a phenomenological approach and the data were analyzed using Braun and Clarke's thematic analysis strategy.</p><p><strong>Results: </strong>Analysis indicated that the two parts of the program called 'knowledge of the disease' and 'management of the disease' with eight related subthemes were crucial for participants' outcomes. In addition, a generic theme called 'motivation and alliance' was identified.</p><p><strong>Conclusion: </strong>The digital self-management intervention MY-ENDO was generally experienced and evaluated as positive. It was considered an advantage that the program was specifically tailored to and targeting endometriosis as well as developed in collaboration with patients. Having a contact person was deemed important with regard to maintenance and motivation suggesting potential consequences for the implementation of this digital solution in clinical practice.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"187"},"PeriodicalIF":2.4,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12001608/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143983828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Body image disturbances in women of childbearing age with polycystic ovary syndrome: a cross-sectional study.","authors":"Qian Gao, Xuan Qian, Jie Zhang, Feng Zhang, Xujuan Xu","doi":"10.1186/s12905-025-03693-4","DOIUrl":"https://doi.org/10.1186/s12905-025-03693-4","url":null,"abstract":"<p><strong>Disign: </strong>This is a cross-sectional study.</p><p><strong>Objectives: </strong>This study aimed to identify the risk factors associated with body image disturbances in patients with polycystic ovary syndrome (PCOS).</p><p><strong>Methods: </strong>This study included married women diagnosed with PCOS who required fertility assistance. Participants were recruited from the reproductive centers of three tertiary hospitals in Jiangsu Province between December 2022-June 2023. We collected 333 patient data through an online questionnaire, body image was assessed by the Chinese version of Body Image Disturbance Questionnaire (BIDQ). The demographic information and clinical data of patients were collected. At the same time, the relevant information of sleep quality, personality traits, intimate relationship, family care and psychological resilience of the patients were collected through various scales. Univariate analysis and a generalized linear model were employed to analyze the factors affecting body image disturbances in women with PCOS.</p><p><strong>Results: </strong>This cross-sectional study included 333 women of childbearing age with PCOS. Univariate analysis revealed that body image was associated with factors such as the body mass index (BMI), occupation, menstrual disturbances, a family history of PCOS, hair loss, acne, hirsutism, scores on the Family Apgar Index, psychological resilience levels, sleep quality, intimate relationship, and personality traits. The generalized linear model demonstrated that occupation, BMI, hair loss, acne, hirsutism, intimate relationship, family care, and psychological resilience were independent risk factors for body image issues.</p><p><strong>Conclusion: </strong>The influencing factors of body image disturbance in patients with polycystic ovary syndrome of childbearing age come from many aspects, including occupation, acne, hair loss, hirsutism, BMI, intimate relationship, family care and psychological resilience. Consequently, medical professionals in obstetrics and gynecology should recognize the body image concerns of women with PCOS and implement specific interventions to support these women during their childbearing years.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"186"},"PeriodicalIF":2.4,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12001658/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143973499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sexual dysfunction in women with genital warts: a cross-sectional study.","authors":"Mohamed S Zaky, Zakaria M Obaid, Ahmed M Youssef, Asmaa D Elmenawy, Mohamed L Elsaie","doi":"10.1186/s12905-025-03691-6","DOIUrl":"https://doi.org/10.1186/s12905-025-03691-6","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate sexual dysfunction and quality of life in women with genital warts.</p><p><strong>Methods: </strong>A total of 100 women were included if they were aged 18-45 years, had genital warts (GWs) for at least three months, and were in a stable marital relationship for at least six months. All participants completed the Female Sexual Function Index (FSFI) and the Dermatology Life Quality Index (DLQI) questionnaires.</p><p><strong>Results: </strong>Showed that the lowest mean scores were observed in the domains of orgasm (1.91 ± 1.07), arousal (2.82 ± 1.12), satisfaction (3.01 ± 1.01), pain (3.11 ± 1.34), desire (3.37 ± 1.01), and lubrication (3.64 ± 1.32). Total FSFI score was 17.64 ± 6.15. The presence of GWs had a significant very large impact on patients QOL in 49% of participants (p < 0.001).</p><p><strong>Conclusions: </strong>Results demonstrated sexual and quality of life affection among females complaining of genital warts. Sexual health and dysfunction should be routinely assessed in women presenting with genital warts.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"188"},"PeriodicalIF":2.4,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12004874/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143982567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endometrial histological patterns and associated factors of abnormal uterine bleeding among women seeking gynecological services from referral hospitals in Western Uganda: a cross-sectional study.","authors":"Joan Logose, Marie Pascaline Sabine Ishimwe, Moses Kabali, Emmanuel Okurut, Emmanuel Eliu, Adam Ddamulira, Theoneste Hakizimana","doi":"10.1186/s12905-025-03722-2","DOIUrl":"https://doi.org/10.1186/s12905-025-03722-2","url":null,"abstract":"<p><strong>Background: </strong>Women of all ages are susceptible to abnormal uterine bleeding (AUB), a relatively frequent gynecological issue. In the gynecology outpatient department, abnormal uterine bleeding is a problem that affects one-third of the patients, making them feel less financially secure and have a lower quality of life. Our study aimed to determine the endometrial histological patterns and factors associated with abnormal uterine bleeding among women seeking gynecological services from referral hospitals in western Uganda.</p><p><strong>Methods: </strong>A cross-sectional study was conducted from June 2023 to September 2023. We systematically enrolled 361 participants after getting consent. A structured questionnaire was used to collect information needed for analysis. The endometrial samples were collected immediately from eligible patients with Abnormal Uterine bleeding and taken to the histopathology laboratory for examination. Descriptive statistics followed by binary logistic regression were conducted to achieve the study objectives.</p><p><strong>Results: </strong>The study enrolled 361 participants with the mean age was 32.7 years (SD = 12.5). Of the total participants, 54(14.96%) had Abnormal Uterine bleeding. The common endometrial histological patterns among women with Abnormal uterine bleeding were; proliferative endometrium 21(38.9%), simple endometrial hyperplasia without atypia 11(20.4%), and secretory Endometrium 6 (11.1%). Women with BMI ranging between 25 and 29.9 [aOR = 5.61 (1.42-22.19), p = 0.014], those with a history of genital infection in the past 1 year [aOR = 2.49 (1.2-5.13),p = 0.013], those who were nulliparous [ aOR = 13.31( 4.94-35.82), p = 0.001], Primiparous [aOR = 4.32( 1.83-10.16), p ≤ 0.001] and women who reported HIV positive serostatus [aOR = 3.65(1.74-7.66), p = 0.001] were independently associated with Abnormal Uterine Bleeding at Fort portal Regional Referral hospital.</p><p><strong>Conclusions and recommendations: </strong>The prevalence of AUB was within the global range. Simple endometrial hyperplasia without atypia and chronic endometritis were the commonest pathological patterns. BMI, History of genital infection, nulliparity, primiparity, and HIV serostatus were the factors that were independently associated with abnormal uterine bleeding. There is a need for routine endometrial sampling for all eligible women with abnormal uterine bleeding at FRRH.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"185"},"PeriodicalIF":2.4,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12001396/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143981071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors influencing abortion duration, bleeding volume, pain scores, and anxiety levels during medical abortion: a cross-sectional study.","authors":"Wenbo Wu, Liyan Wang, Xiangfei Zhu, Wenjuan Wan, Waixiang Yuan, Qianqian Jiang, Yun Gao, Wei Cheng, Yuehui Zheng, Yanhong Du","doi":"10.1186/s12905-025-03672-9","DOIUrl":"https://doi.org/10.1186/s12905-025-03672-9","url":null,"abstract":"<p><strong>Background: </strong>Some factors that influence the medical abortion(MA) process are unknown. This study aims to investigate the influential factors associated with abortion time, bleeding volume, pain scores, and anxiety during the process of MA.</p><p><strong>Methods: </strong>A cross-sectional design was used in this research. Demographic information, pregnancy duration, bleeding volume, abortion duration, pain scores, anxiety levels, step count, and rate were recorded for each participant throughout MA. Data analysis was conducted using the SPSS version 26.0.</p><p><strong>Results: </strong>The mean age of the 450 women included in the study was 32.14 ± 5.57 years. The study revealed that older age correlates with longer abortion duration (rs = 0.102, P < 0.05) but lower pain scores during MA (rs=-0.178, P < 0.001). A history of dysmenorrhea shortened abortion time (rs=-0.097, P < 0.05) but increased pain (rs = 0.106, P < 0.05) and anxiety (rs = 0.119, P < 0.05). Women with cesarean section histories reported less pain (rs=-0.226, P < 0.001) and anxiety (rs=-0.129, P < 0.001) during MA. Vaginal delivery history decreased pain scores (rs=-0.117, P < 0.05) but did not significantly affect other outcomes. Previous surgical abortion alleviated pain (rs=-0.139, P < 0.001) and anxiety (rs=-0.093, P < 0.05) during MA. Increased walking steps or faster step rates shortened abortion duration (rs=-0.107, P < 0.05; rs=-0.133, P < 0.05) but raised pain scores (rs = 0.258, P < 0.001; rs = 0.235, P < 0.001).</p><p><strong>Conclusions: </strong>Individuals with dysmenorrhea and high physical activity (PA)may have shorter abortion durations. Older individuals and those with cesarean or surgical abortion histories may experience less pain during medical abortion. Dysmenorrhea correlates with higher anxiety, while cesarean sections and surgery abortion lower it.</p><p><strong>Trial registration: </strong>This research has been filed with the National Research Filing Center system under file number MR-44-24-032502.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"183"},"PeriodicalIF":2.4,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12001470/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143970944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}