BMC Women's Health最新文献

{"title":"The association between insulin resistance and urge urinary incontinence in non-diabetic women is primarily mediated by obesity: a cross-sectional study based on NHANES from 2005 to 2016.","authors":"Shuxin Li, Tong Yang, Xin Lian","doi":"10.1186/s12905-025-04002-9","DOIUrl":"10.1186/s12905-025-04002-9","url":null,"abstract":"","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"429"},"PeriodicalIF":2.7,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12442289/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145079705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acceptability and effectiveness of empathy-based provider training and community-level awareness activities on self-injectable contraceptive use in Niger, Lagos, and Oyo States, Nigeria: a mixed methods program evaluation.","authors":"Susan Ontiri, Claire W Rothschild, Fauzia Tariq, Oluwaseun Adeleke, Michael Titus, Mopelola Raji, Julius Njogu, Susannah Gibbs, Robin Swearingen, Fidelis Edet","doi":"10.1186/s12905-025-03992-w","DOIUrl":"10.1186/s12905-025-03992-w","url":null,"abstract":"<p><strong>Background: </strong>Interventions aimed to increase healthcare provider empathy and capacity to deliver person-centered care have been shown to improve healthcare seeking and outcomes. In the context of self-injectable contraception, empathetic counseling and coaching may be promising approaches for addressing \"fear of the needle\" among clients interested in using subcutaneous depot medroxyprogesterone (DMPA-SC). In Nigeria, the Delivering Innovation in Self-Care (DISC) project developed and evaluated an empathy-based in-service training and supportive supervision intervention for public sector family (FP) planning providers implemented in conjunction with community-based mobilization.</p><p><strong>Methods: </strong>The DISC intervention was evaluated using a quasi-experimental mixed methods design. Effectiveness of the intervention on DMPA-SC service delivery, including self-injection (SI) and provider administration, was assessed using a single-group interrupted time series design that leveraged phased implementation in 36 facilities. Service delivery data were extracted from the Nigerian Health Information System for the pre-intervention period and using program monitoring tools for the intervention and post-training maintenance period. Outcomes were modeled using linear generalized estimating equations. In-depth interviews were conducted with trained providers to assess acceptability and perceived changes in SI attitudes and behaviors.</p><p><strong>Results: </strong>Mean DMPA-SC service provision increased by 28.1 visits on average per facility in the first month of implementation, relative to a pre-intervention data strengthening phase (95% confidence interval [CI] 18.0-38.3). The intervention was associated with an increase in mean facility-level SI service delivery of 25.9 visits (95% CI 16.3-35.4). The intervention was associated with overall increases in FP service delivery. Increases in DMPA-SC service provision were sustained in the post-training maintenance period. In qualitative interviews, trained providers reported increased client demand for SI, coupled with increased provider confidence to counsel and train clients to self-inject. While providers indicated that stockouts of intramuscular DMPA (DMPA-IM) resulted in shifts towards DMPA-SC, we did not observe decreases in DMPA-IM or long-acting reversible contraception provision in the quantitative data.</p><p><strong>Discussion: </strong>Our findings demonstrate the effectiveness and acceptability of a program combining supply- and demand-side interventions aimed at expanding awareness and access to self-injectable contraception in Nigeria. In this context, providers highly valued in-service training and ongoing support that built capacity for empathetic client engagement.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 Suppl 1","pages":"428"},"PeriodicalIF":2.7,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12421749/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145028916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Injectable contraceptive continuation and user experiences in Punjab, Pakistan: a non-randomized prospective cohort study protocol.","authors":"Hannah Tappis, Kanwal Qayyum, Emily Bryce, Aisha Fatima, Megan Christofield, Huma Haider, Afshan Ameen, Syed Muhammad Akbar Gardezi, Fazal Rafay, Fauzia Assad","doi":"10.1186/s12905-025-03969-9","DOIUrl":"10.1186/s12905-025-03969-9","url":null,"abstract":"<p><strong>Background: </strong>Evidence from multiple pilots and post-introduction scale-up initiatives have demonstrated that self-administered subcutaneous depot-medroxyprogesterone acetate (DMPA-SC) has potential to improve contraceptive continuation rates and expand contraceptive access to populations with limited utilization of facility-based health services. Only a few of these studies have been conducted in South Asian countries, and none where most contraceptive use is of non-hormonal methods that require limited to no contact with the health system, leaving policymakers in countries like Pakistan with limited context-specific evidence to guide decisions on whether, how, and for whom to introduce DMPA-SC.</p><p><strong>Methods: </strong>A prospective cohort study will be conducted in 41 health facilities and surrounding communities in Punjab, Pakistan. The primary objective of the study is to compare the 12-month contraceptive continuation rate for women who receive DMPA-SC with that for women who receive intramuscular depot-medroxyprogesterone acetate (DMPA-IM). The secondary objectives are to compare characteristics and experiences of participants who opt for DMPA-SC with those of women who opt for DMPA-IM, which must be administered by a health worker. Additionally, a sub-study is planned to assess how well women opting for self-injection of DMPA-SC adhere to standards for commodity storage, injection timing, injection technique and waste disposal.</p><p><strong>Discussion: </strong>This research offers an opportunity to contribute to global efforts to reduce inequities in access to contraceptive method choices, while generating actionable evidence to inform health sector decision-making in Pakistan. Although study sites are limited to health facilities where a woman's first self-injection of DMPA-SC is supervised by a nurse, midwife, medical officer, Lady Health Visitor, Family Welfare Worker or Family Welfare Councilor, the research protocol and findings will provide a foundation for future studies testing alternative service provision and self-injection support models.</p><p><strong>Trial registration: </strong>Registered on clinicaltrials.gov as an observational study (NCT05774626).</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 Suppl 1","pages":"427"},"PeriodicalIF":2.7,"publicationDate":"2025-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12416068/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145013741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lessons from the scale-up of provider-administered and self-injection of DMPA-SC in Nigeria: a landscape assessment.","authors":"Adewole A Adefalu, Tolulope O Afolaranmi, Ebony Fontenot, Rachel Simon, Miranda Buba, Victor Dafe, Funmilayo Olabode, Mary Ajayi, Olajimi Latunji, Joy M Dogo","doi":"10.1186/s12905-025-03938-2","DOIUrl":"10.1186/s12905-025-03938-2","url":null,"abstract":"<p><strong>Background: </strong>Nigeria is the seventh-most populous country in the world. Its high fertility rate and unmet need for family planning contribute to the increasing population size. To reduce this gap, the Federal Government of Nigeria, in collaboration with Injectables Access Collaborative and other public and private sector players, introduced the subcutaneous depot medroxyprogesterone acetate (DMPA-SC) to the contraceptive method mix in 2017. We conducted an assessment to document the implementation experiences and best practices from the introduction of provider-administered and self-injection (SI) of DMPA-SC from the perspective of the government and implementing partners across states and federal governments levels from the supply-side. This is meant to serve as a learning resource to provide empirical evidence to help inform the DMPA-SC programming.</p><p><strong>Methods: </strong>A cross-sectional study design that employed a mixed-method approach to data collection was used for this assessment. Our methods included desk review of existing DMPA-SC implementation documents and key informant interviews conducted on 13 government and implementing partners across states and federal levels. Narrative summarization and graphical trend analysis were used for the presentation of information obtained from document review while Nvivo software (version 12) was used for the analysis of transcripts of the KIIs.</p><p><strong>Results: </strong>This assessment revealed a positive trend in the use of provider-administered and self-injection DMPA-SC from 2020 to 2023. This was supported by functional policies and guidelines. Implementing the Task Shifting and Task Sharing policy continuously; strengthening referral systems for provider-administered and self-injection DMPA-SC programme; and decentralising family planning services were suggested mechanisms for strengthening DMPA-SC programme implementation in Nigeria. However, funding gaps, human resource constraints, and weak coordination mechanisms impeded DMPA-SC implementation scale up.</p><p><strong>Conclusion: </strong>This assessment illustrates the influence of an enabling environment and stakeholder commitment on the positive trend in provider-administered and self-injection DMPA-SC uptake in Nigeria. Training service providers and improving funding through the use of innovative financing were recommended as levers for DMPA-SC programme sustainability and service scale-up.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 Suppl 1","pages":"426"},"PeriodicalIF":2.7,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12413743/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145005964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges and opportunities in coordinating investments across countries and channels to expand access to a new contraceptive method.","authors":"Kaleigh MacDaniels","doi":"10.1186/s12905-025-03949-z","DOIUrl":"10.1186/s12905-025-03949-z","url":null,"abstract":"","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 Suppl 1","pages":"425"},"PeriodicalIF":2.7,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12409935/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144991169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effectiveness of vitamin B6 in reducing mastalgia: a systematic review and meta-analysis.","authors":"Foruzan Sharifipour, Shahla Faal Siahkal, Marzieh Bagherinia","doi":"10.1186/s12905-025-03991-x","DOIUrl":"10.1186/s12905-025-03991-x","url":null,"abstract":"<p><strong>Background: </strong>Mastalgia represents the most frequent complaint among women at some point during their lives that can have a profound impact on both the physical and mental well-being of individuals affected by this condition. This study aims to systematically evaluate the effect of vitamin B6 on the severity of mastalgia.</p><p><strong>Design: </strong>This study is a meta-analysis of interventional studies that compare the effects of vitamin B6 to a placebo in healthy women with Mastalgia. The literature search encompassed studies published from inception until November 2024 and was conducted across various electronic databases, including Web of Science, Embase, Cochrane Library, Scopus, PubMed, and Google Scholar, in both English and Persian languages. The severity of breast pain was considered as the outcome measure. Breast pain linked to the menstrual cycle is called cyclic breast pain or cyclic mastalgia. The data were analyzed using Stata software version 17 and a random effects model. The quality of the selected articles was assessed utilizing the Cochrane Risk of Bias assessment checklist.</p><p><strong>Results: </strong>A total of 301 studies with N = 951 participants (intervention:536, control: 415) were reviewed, with three studies ultimately included in the meta-analysis. The combined analysis of these three studies indicated that there were no differences between the two groups of vitamins B6 and placebo in a reduction of pain intensity (SMD = -3.57, 95% CI: -9.15 to 2.01; very low certainty of evidence), with high heterogeneity among the studies (I² = 99.56%). The overall quality of the included studies was assessed to be low.</p><p><strong>Conclusion: </strong>This meta-analysis did not demonstrate a statistically significant effect of vitamin B6 on mastalgia severity. The evidence is limited by the small number of available studies, low methodological quality, and substantial clinical and statistical heterogeneity. Further well-designed, large-scale randomized controlled trials are needed to reliably determine the efficacy of vitamin B6 for mastalgia. PROSPERO CRD 42,024,613,796.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"421"},"PeriodicalIF":2.7,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12403960/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Loneliness and analgesic overuse among low-dose estrogen-progestin users in Japan.","authors":"Takuma Fujimoto, Hiroki Iwata, Noriko Kobayashi, Shingo Kondo, Katsunori Yamaura","doi":"10.1186/s12905-025-03970-2","DOIUrl":"10.1186/s12905-025-03970-2","url":null,"abstract":"<p><strong>Purpose: </strong>Loneliness is related to menstrual disorders and medication use. Loneliness and pain are related and may be associated with analgesic use. The aim of this study was to investigate the prevalence of concomitant analgesic use and overuse, and to clarify factors associated with loneliness and analgesic overuse among women who are low-dose estrogen-progestin (LEP) users.</p><p><strong>Methods: </strong>Women in their 20s and 30s were randomly selected from a research company's web panel (Macromill, Inc.) and LEP users were screened. The survey included analgesic concomitant use days per month and the Three-Item Loneliness Scale (TIL). Logistic regression analysis was performed with high TIL score (≥ 6) and analgesic use ≥ 10 days per month as the objective variables.</p><p><strong>Results: </strong>A total of 516 valid responses from LEP users were analyzed. Among them, 64.1% reported concomitant analgesic use on ≥ 1 day per month, 11.2% on ≥ 10 days per month, and 45.7% had high TIL score. High TIL score was significantly associated with concomitant analgesic use on ≥ 1 day per month (odds ratio [OR] 1.76, 95% confidence interval [95%CI] 1.18-2.63, p = 0.006). Concomitant analgesic use on ≥ 10 days per month was significantly associated with endometriosis (OR 5.25, 95%CI 2.15-12.81, p < 0.001) and concomitant analgesic use for low back pain (OR 4.67, 95%CI 1.65-13.18, p = 0.04).</p><p><strong>Conclusions: </strong>To our knowledge, this is the first detailed study to investigate concomitant analgesic use and overuse among LEP users. Loneliness was found to be prevalent in this population and was associated with concomitant analgesic use, potentially reflecting underlying patterns of frequent or habitual analgesic intake. Furthermore, concomitant analgesic overuse was linked to conditions such as endometriosis and low back pain, underscoring the importance of medication monitoring that takes into account both loneliness and the self-recording of menstrual symptoms. Greater attention by healthcare professionals to the psychosocial context of concomitant analgesic overuse and loneliness may facilitate more meaningful patient dialogue and contribute to improved quality of life.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"422"},"PeriodicalIF":2.7,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12403348/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global, regional and national uterine fibroid burdens from 1990 to 2021 and projections until 2050: results from the GBD study.","authors":"Zihan Zhang, Hongxin Huang, Kuanlie Jiang, Weixia Liu, Yan Xuan, Wei Lu","doi":"10.1186/s12905-025-03974-y","DOIUrl":"10.1186/s12905-025-03974-y","url":null,"abstract":"<p><strong>Background: </strong>Uterine fibroids(UF), while histologically benign, constitute a pervasive yet inequitable epidemiological phenomenon characterized by disproportionately distributed morbidity burdens that correlate asymmetrically with regional development levels, compounded by intersecting socioeconomic determinants and genetic susceptibilities. We aimed to assess the global and regional burden of age-standardized UF in women from 1990 to 2021.</p><p><strong>Methods: </strong>Age-standardized incidence, prevalence, and years lived with disability (YLDs) rates attributable to UF were obtained from the Global Burden of Disease (GBD) Study 2021. Temporal trends were evaluated using the average annual percentage change (AAPC), and future projections were conducted using the autoregressive integrated moving average (ARIMA) model.</p><p><strong>Results: </strong>From 1990 to 2021, the global Age-standardized prevalence rate (ASPR) increased (AAPC = 0.05; 95% CI: 0.03 to 0.08), with the high increases occurring in Brazil, India, and Georgia. The Age-standardized incidence rate (ASIR) also increased globally (AAPC = 0.23; 95% CI: 0.19 to 0.27), although it declined in Poland. Age-standardized years lived with disability (YLDs) followed a similar global upward trend (AAPC = 0.09; 95% CI: 0.07 to 0.12) but decreased in some regions, including China, and Australia. The high-middle-SDI regions exhibited declining trends, whereas the low-middle-SDI regions exhibited increasing trends. Our projections suggested stabilization of these indicators by 2050.</p><p><strong>Conclusions: </strong>UF remain the most common benign gynecological tumors and pose a substantial health care burden. Socioeconomic factors, diagnostic advancements, and lifestyle changes influence the long-term trends associated with their prevalence, incidence, and other related parameters. Increased epidemiological surveillance and more public health interventions are needed.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"423"},"PeriodicalIF":2.7,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12403543/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Cervical and vaginal metastases from ascending colon cancer: a case report and literature review.","authors":"Fangfang Nie, Haibo Si, Haojie Qin, Yuanhe Wang, Yongpeng Wang","doi":"10.1186/s12905-025-03978-8","DOIUrl":"10.1186/s12905-025-03978-8","url":null,"abstract":"","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"420"},"PeriodicalIF":2.7,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12403552/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Career advancement and fertility intention among working women in Japan: a cross-sectional survey study.","authors":"Honami Yoshida, Mariko Nishikitani, Masumi Okamoto, Akio Kurokawa, Mika Hoshina, Mizuki Yazawa, Nao Ichihara","doi":"10.1186/s12905-025-03996-6","DOIUrl":"10.1186/s12905-025-03996-6","url":null,"abstract":"<p><strong>Background: </strong>The global decline in birth rates highlights the need to understand fertility intention among working women of childbearing age. However, only few studies have examined the balance between career and childbearing in Japan, which has a rapidly aging society. This study aimed to explore factors influencing fertility intention by evaluating health status, healthcare access, career advancements, working conditions, and workplace dynamics among Japanese working women.</p><p><strong>Methods: </strong>This cross-sectional study used data from the Working Women's Health Score survey, a collaboration between industry and academia, aimed at evaluating female employees' health and working environments at 14 companies. Participants were women aged 19-65 years working at companies in the Marunouchi area of Tokyo, Japan. A total of 3,425 women completed an online health survey between September 13 and October 11, 2022. The survey collected information on demographic characteristics, childbearing status and intentions, health status, gynecological history, lifestyle, healthy habits, working styles, and workplace environments. To identify factors associated with childbearing intention, working women under 40 years (n = 1,621) were categorized as those with and those without fertility intention. Participants with children who wished to have more children in the future were assigned to the fertility intention group.</p><p><strong>Results: </strong>Women in the fertility intention group were more likely to be younger, married, and proactive about their health. They reported greater confidence in their physical health and better sleep quality. No significant differences were observed between the groups regarding severity of dysmenorrhea, premenstrual syndrome, or overall health literacy. Women in the fertility intention group were more likely to be regular full-time workers, work in sales rather than clerical positions, and be more motivated for career advancement. Workplace environment factors, including job engagement and male colleagues' understanding of female-specific symptoms, did not significantly differ between the two groups.</p><p><strong>Conclusions: </strong>Job stability, job type, career motivation, confidence, and proactive health management are associated with fertility intention among working women in Japan. Women assured of career advancement may also be more inclined to plan for childbearing, highlighting the importance of workplace policies supporting career development and family planning.</p>","PeriodicalId":9204,"journal":{"name":"BMC Women's Health","volume":"25 1","pages":"424"},"PeriodicalIF":2.7,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12403544/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}