BMC Pediatrics最新文献

{"title":"Functional accessory limb arising from the buttock: a case report.","authors":"Mohammad Mahdi Ebrahiminasab, Taghi Baghdadi, Pouya Tabatabaei Irani, Soroush Baghdadi","doi":"10.1186/s12887-025-05712-7","DOIUrl":"https://doi.org/10.1186/s12887-025-05712-7","url":null,"abstract":"<p><strong>Background: </strong>Polymelia, or accessory limb, is a rare congenital abnormality with unknown etiology. Here we report the case of an infant with an accessory limb, review the diagnostic and therapeutic consideration of such cases, and highlight the potential challenges in management of an accessory limb.</p><p><strong>Case presentation: </strong>We report the case of a 2-month-old male with an accessory limb arising from the left buttock. The limb was sensate and mobile joints. Our diagnostic workup did not reveal associated spinal dysraphism, but a left dislocated hip was found. The limb was surgically removed, and the hip dislocation was eventually treated with open reduction, with excellent results.</p><p><strong>Conclusion: </strong>This study reports a rare case of accessory limb and reviews the important considerations in the management of this condition.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":9144,"journal":{"name":"BMC Pediatrics","volume":"25 1","pages":"357"},"PeriodicalIF":2.0,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12054316/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143953910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes of laparoscopic appendectomy of a normally appearing appendix in children with suspected acute appendicitis: a tertiary care center experience.","authors":"Wael Abosena, Mohamed Ahmed Elghazeery, Hisham Almohamady Almetaher, Ahmed Mostafa Aboelyazeed","doi":"10.1186/s12887-025-05630-8","DOIUrl":"https://doi.org/10.1186/s12887-025-05630-8","url":null,"abstract":"<p><strong>Background: </strong>There is a lack of consensus among pediatric surgeons regarding the optimal management of a macroscopically normal appendix encountered during laparoscopy in children with suspected acute appendicitis. We hereby present our experience with laparoscopic appendectomy for macroscopically normal appendix in children with suspected acute appendicitis, evaluating its efficacy, safety, and postoperative histopathological findings of the excised specimens.</p><p><strong>Methods: </strong>This retrospective study was conducted on 221 children with acute right lower quadrant abdominal (RLQA) pain and had a high clinical suspicion of acute appendicitis between January 2018 and January 2022. Among these, 38 patients were found to have a macroscopically normal appendix during surgery. All patients underwent appendectomy, and the excised specimens were sent for histopathological examination.</p><p><strong>Results: </strong>Following laparoscopic appendectomy for macroscopically normal appendices in 38 children with suspected acute appendicitis, histopathological examination revealed pathological changes in 32 specimens (84%). Catarrhal appendicitis was identified in 26 cases (68%), fecalith obstruction in 5 cases (13%), and phlegmonous appendicitis in 1 case (3%), while only 6 specimens (16%) were histologically normal. The mean operative time was 51 min, with no conversions to open surgery. Postoperative complications occurred in 2 patients (5%), including one case of hyperpyrexia and one wound infection, both managed conservatively. The average hospital stay was 23.9 h, with 89% of patients discharged within 24 h. Postoperatively, all patients had complete RLQA pain resolution, with no complications or symptom recurrence during the three-month follow-up.</p><p><strong>Conclusion: </strong>Our study supports appendectomy in pediatric patients undergoing laparoscopy for suspected acute appendicitis when no other pathology is identified, even if the appendix appears normal. This approach is justified with low morbidity, short hospital stays, symptom resolution without recurrence and only 16% of normal-looking appendices confirmed as histologically normal. However, larger multi-centre studies are needed to validate and standardize this practice.</p>","PeriodicalId":9144,"journal":{"name":"BMC Pediatrics","volume":"25 1","pages":"356"},"PeriodicalIF":2.0,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12054081/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143953539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determinants of physical activity level in pediatric oncological patients treated with cardiotoxic therapy - a study protocol.","authors":"Julia Haponiuk-Skwarlińska, Jakub S Gąsior, Katarzyna Albrecht, Paweł Łaguna, Bożena Werner","doi":"10.1186/s12887-025-05714-5","DOIUrl":"10.1186/s12887-025-05714-5","url":null,"abstract":"<p><strong>Background: </strong>Childhood cancer and its therapy, especially that involving potentially cardiotoxic cancer treatment, can structurally affect muscle strength and heart function, and therefore may result in lowered physical activity (PA). This study protocol aims to find the significant determinants of PA levels in pediatric oncological patients 1-5 years after heart-toxic chemotherapy and/or radiation of the heart region.</p><p><strong>Methods: </strong>The study group will include children 1-5 years after completing cancer therapy involving cardiotoxicity risk factors. The primary outcome of interest is the PA measured with an ActiGraph GT3X Accelerometer for 14 consecutive days and the assessment of WHO pediatric age-adjusted PA norms achievement. Assessed PA levels will be evaluated according to the possible determinants of PA: disease/treatment related risk factors, treatment complications, possible complications after the treatment, cardiac function with echocardiography including 2D and 3D strain imaging, physical function and muscle strength in ALPHA (Assessing Levels of Physical Activity) health-related fitness test battery and exercise capacity in cardiopulmonary exercise testing. The self-efficacy and motivation to PA, quality of life (QoL), lifestyle, socio-demographic, and anthropogenic factors as well as knowledge about the positive impact of PA will be evaluated with original and validated questionnaires. The PA determinants of the study group will be compared to the results of the control group of children in the same follow-up period (> 1 year < 5 years) after completing cancer therapy without cardiotoxic methods.</p><p><strong>Discussion: </strong>The results may contribute to the development of future recommendations on prophylactic and therapeutic approaches, as well as proper lifestyle recommendations for children in long-term follow-up after cardiotoxic cancer therapy. The determinants will be used to develop targeted exercise prescriptions and exercise programs.</p><p><strong>Trial registration: </strong>NCT06256068.</p>","PeriodicalId":9144,"journal":{"name":"BMC Pediatrics","volume":"25 1","pages":"355"},"PeriodicalIF":2.0,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12051312/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143958494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"I made friends a lot more easily\": children and families' experiences of social group programs for children on the autism spectrum.","authors":"Maya Hayden-Evans, Bahareh Afsharnejad, Elinda Ai Lim Lee, Ben Milbourn, Tanya Picen, Mathew Johnson, Sven Bölte, Sonya Girdler","doi":"10.1186/s12887-025-05686-6","DOIUrl":"https://doi.org/10.1186/s12887-025-05686-6","url":null,"abstract":"<p><strong>Background: </strong>Social Skills Group Programs (SSGP) target the social communication and interaction skills of children on the autism spectrum. This qualitative study explored lived experiences of children and families who participated in a randomised controlled trial (RCT) evaluating the efficacy of KONTAKT™ adapted for younger children (8 to 12 years) in comparison to an active control social art group (ART Legends).</p><p><strong>Methods: </strong>Semi-structured interviews were conducted online with parents (n = 37) and children (n = 35) who participated in the RCT, immediately following the interventions. Interview questions were designed to elicit responses relating to program content, structure, and experiences. The data were analysed using a deductive coding framework.</p><p><strong>Results: </strong>Findings suggest SSGPs such as KONTAKT™, implementing multiple teaching strategies, and less structured social group activities such as ART Legends can both have a perceived positive influence on outcomes. More children in the KONTAKT™ group reportedly improved their social skills than those in the art group. Overall, participants' experiences were predominantly positive. Both barriers (e.g., session timing, distance from home) and facilitators (e.g., support of family members) to participation were identified; feelings towards individual aspects of the groups were dependent on a range of personal factors (e.g., existing commitments).</p><p><strong>Conclusion: </strong>This study describes experiences of organised social group participation from the perspectives of children on the spectrum and their families, supporting the positive influence of such contexts for autistic youth. Suggestions made by participants to improve social groups are presented, contributing to ongoing development of SSGPs for children on the spectrum.</p><p><strong>Trial registration: </strong>(1) Australian New Zealand Clinical Trials Registry (ANZCTR): ACTRN12619000994189, registered 12 July 2019, anzctr.org.au; (2) ClinicalTrials.gov: NCT04024111 registered 1 December 2019, https://clinicaltrials.gov .</p>","PeriodicalId":9144,"journal":{"name":"BMC Pediatrics","volume":"25 1","pages":"353"},"PeriodicalIF":2.0,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12048955/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143964393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of congenital heart disease on clinical outcomes of oral propranolol therapy for Infantile hemangiomas: a propensity score-matched analysis.","authors":"Junsong Yu, Tao Lei, Lu Gao, Zhihong Huang, Yang Bi, Yun He, Wei Feng","doi":"10.1186/s12887-025-05707-4","DOIUrl":"https://doi.org/10.1186/s12887-025-05707-4","url":null,"abstract":"<p><strong>Background: </strong>Oral propranolol is the first-line treatment for Infantile hemangioma (IH). However, there is a lack of studies indicating whether the congenital heart disease (CHD) makes a difference in oral propranolol therapy (OPT). Previous studies have only confirmed the safety and efficacy of OPT in asymptomatic CHD children.</p><p><strong>Objective: </strong>This study aimed to evaluate and compare the clinical outcomes in pediatric patients with CHD and those without CHD following OPT and to assess risk factors that may contribute to recurrence.</p><p><strong>Methods: </strong>A total of 310 children who received OPT for IH between January 2020 and January 2023 were included in a retrospective study. The study aimed to assess demographic data, clinical symptoms, auxiliary examinations, and treatment effects. To compare clinical outcomes between children with and without CHD, one-to-one propensity score matching (PSM) was applied.</p><p><strong>Results: </strong>Among the 310 patients, 192 (61.94%) had CHD. After propensity-matching analysis, in the presence of CHD, the age at treatment withdrawal was significantly higher (15.0 months vs. 12.0 months, P < 0.05), the treatment duration was longer (12.0 months vs. 10.0 months, P < 0.05), and the recurrence rate was greater (32.9% vs. 5.3%, P < 0.001). No significant difference in the degree of regression was observed between the CHD and non-CHD groups.</p><p><strong>Conclusion: </strong>Pediatric patients with CHD exhibit a later age at treatment withdrawal, a longer duration of therapy, and a higher recurrence rate compared to those without CHD.</p>","PeriodicalId":9144,"journal":{"name":"BMC Pediatrics","volume":"25 1","pages":"354"},"PeriodicalIF":2.0,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12048930/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143976516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Overweight and obesity among adolescents in Saudi Arabia: a multi-school cross-sectional study.","authors":"Hebah A Kutbi, Walaa A Mumena","doi":"10.1186/s12887-025-05633-5","DOIUrl":"https://doi.org/10.1186/s12887-025-05633-5","url":null,"abstract":"<p><strong>Background: </strong>Obesity in adolescence may track into adulthood. Understanding the multifactorial nature of obesity is necessary to curb the growing trends. This study aimed to provide updated estimates on the prevalence of overweight and obesity among adolescents and to scrutinize the associations with parental weight status and various lifestyle and socioeconomic factors.</p><p><strong>Methods: </strong>For this cross-sectional study, participants were recruited from 16 schools located in Jeddah and Madina, Saudi Arabia. Data of 522 adolescents (11-18 years of age) and their parents were collected through self-administered questionnaires. Anthropometric measurements of adolescents were assessed at the school sites. Logistic regression with complex sampling adjustments was conducted to examine the associations of adolescent overweight or obesity with various lifestyle and socioeconomic factors and parental weight status.</p><p><strong>Results: </strong>Overweight and obesity was prevalent by 13.2% and 26.1%, respectively. Living in a single-parent household, maternal obesity, and the coexistence of parental obesity were associated with an increased likelihood of overweight or obesity in adolescents. Stratified analyses by adolescent sex revealed different associations for boys and girls.</p><p><strong>Conclusions: </strong>Our findings highlight the importance of the family environment and the necessity to enroll parents when implementing adolescence obesity prevention programs. Health promotion strategies that promote environmental changes related to healthy lifestyle and dietary practices are needed to eliminate the rising obesity trends.</p>","PeriodicalId":9144,"journal":{"name":"BMC Pediatrics","volume":"25 1","pages":"350"},"PeriodicalIF":2.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12046719/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144062154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subtypes of tic disorders in children and adolescents: based on clinical characteristics.","authors":"Kai Yang, Wenyan Zhang, Ying Li, Xianbin Wang, Zhongliang Jiang, Shujin Hu, JinHyun Jun, Qinghao Yang, Jingyi Li, Xu Hong, Yonghua Cui, Tianyuan Lei","doi":"10.1186/s12887-025-05698-2","DOIUrl":"https://doi.org/10.1186/s12887-025-05698-2","url":null,"abstract":"<p><strong>Background: </strong>Tic disorder (TD) is a diverse neurodevelopmental disorder with various symptoms and comorbidities. Traditional classifications based on age onset and duration fail to adequately characterize the full clinical features of TD. This study aims to redefine TD subtypes by a comprehensive analysis of clinical features and comorbidities.</p><p><strong>Methods: </strong>We assessed 139 children and adolescents aged 6-18 years using 14 scales covering 43 dimensions. The k-means clustering algorithm was used to identify distinct TD subtypes. Differences between these subtypes were analyzed using t-tests and network analysis, with high expected influence (EI) metric representing key symptoms within each subtype.</p><p><strong>Results: </strong>We identified two distinct subtypes of TD, with 21.6% of participants classified as subtype1 and 78.4% as subtype2. Subtype1 exhibited more severe symptoms across TD, obsessive-compulsive spectrum disorders, and attention deficit hyperactivity disorder assessments compared to subtype2, with significant differences observed in 81.4% of the scale features. Network analysis revealed differences in core symptoms between the two subtypes; subtype1 primarily involved hyperactivity and vital activities, whereas subtype2 primarily involved attention deficit, hyperactivity and conduct. Furthermore, comparisons with DSM-5 classifications revealed distinct patterns, indicating the novel nature of the identified subtypes.</p><p><strong>Conclusion: </strong>Our study identified two novel TD subtypes, highlighting its heterogeneity. Subtype 1 had more severe attention deficits and impulsivity, requiring comprehensive treatment, while subtype 2 had milder symptoms, focusing on support and monitoring. These findings provide insights into TD classification and may help refine treatment strategies. However, the cross-sectional design limits causal interpretations, and reliance on parent-reported data may introduce bias.</p>","PeriodicalId":9144,"journal":{"name":"BMC Pediatrics","volume":"25 1","pages":"349"},"PeriodicalIF":2.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12046735/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143981400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Autoimmune polyendocrine syndrome type 2 in children: a case report and literature review.","authors":"Yahong Liu, Fei Wang, Lijuan Zhang, Hongxiao Zhang, Yanfang Zhu","doi":"10.1186/s12887-025-05697-3","DOIUrl":"https://doi.org/10.1186/s12887-025-05697-3","url":null,"abstract":"<p><strong>Background: </strong>Autoimmune polyendocrine syndrome (APS) is a clinical disorder characterized by the loss of immune tolerance, leading to dysfunction in multiple endocrine glands. According to the latest disease classification, APS is categorized into three main subtypes: APS-1, APS-2, and IPEX (Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-linked) syndrome. APS-2 is defined by the presence of at least two autoimmune endocrine disorders, such as type 1 diabetes mellitus, autoimmune thyroiditis, or Addison's disease. APS-2 typically manifests later than APS-1, with onset most commonly occurring in early adulthood. However, pediatric cases involving a combination of autoimmune thyroid disease, type 1 diabetes mellitus, and myasthenia gravis, are extremely rare.</p><p><strong>Case presentation: </strong>This article reported the case of a 3-year-old girl diagnosed with autoimmune polyendocrine syndrome type 2 (APS-2). The patient initially presented with hyperthyroidism and exophthalmos and was subsequently diagnosed with type 1 diabetes mellitus and myasthenia gravis. To our knowledge, this case represents the youngest reported patient of APS-2 at the time of diagnosis, as well as the shortest documented interval between the onset of autoimmune disorders affecting distinct endocrine glands.</p><p><strong>Conclusions: </strong>Through a retrospective analysis, we comprehensively reviewed the phenotypic characteristics of APS-2 and explored its potential immune mechanisms. This article aims to provide clinicians with a valuable reference case to enhance early recognition and facilitate the implementation of targeted prevention and treatment strategies.</p>","PeriodicalId":9144,"journal":{"name":"BMC Pediatrics","volume":"25 1","pages":"351"},"PeriodicalIF":2.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12046904/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143976372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic accuracy of visual triage checklist in early recognition of COVID-19 cases in the pediatric population: A retrospective cohort study.","authors":"Ayesha Imtiaz, Abdullah Y Akkam, Lulwah H AlThumali, Ahlam M AlHarthi, Honey G Porte, Wesal S AlOsaimi, Maha M A AlAsmari, Rawda B G Salih, Biswadev Mitra","doi":"10.1186/s12887-025-05693-7","DOIUrl":"https://doi.org/10.1186/s12887-025-05693-7","url":null,"abstract":"<p><strong>Background: </strong>During the coronavirus disease 2019 (COVID-19) pandemic, healthcare facilities developed surveillance systems to identify patients suspected of having COVID-19 to segregate them during their hospital stay. As a part of this infection control strategy, the Ministry of Health in the Kingdom of Saudi Arabia developed a visual triage (VT) checklist for early screening and isolation of patients in the hospital. The aim of this study was to evaluate the diagnostic accuracy of this visual triage checklist in identifying children with COVID-19.</p><p><strong>Methods: </strong>This was a retrospective, single center study that included all children who were tested for COVID-19 and were admitted to the hospital through the pediatric emergency department. The diagnostic accuracy of the visual triage checklist was assessed using COVID-19 PCR as the gold standard.</p><p><strong>Results: </strong>A total of 1333 patients were included. The visual triage checklist had a sensitivity of 94.3% (95% CI: 87.2-98.1) and a specificity of 16.0% (95% CI: 14-18) with an area under the receiver operating characteristic curve of 0.55 (0.53-0.58). The positive predictive value of the checklist was low at 7.35% (95% CI: 5.9-9.0).</p><p><strong>Conclusion: </strong>The VT checklist has high sensitivity, and is therefore potentially useful as an initial screening tool. However, the diagnosis of COVID-19 requires early secondary confirmation to avoid the large number of false positive cases associated with this tool.</p>","PeriodicalId":9144,"journal":{"name":"BMC Pediatrics","volume":"25 1","pages":"352"},"PeriodicalIF":2.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12046900/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143977460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Single-incision versus conventional multiport laparoscopic-assisted surgery for Meckel's diverticulum in children: a single-center propensity score analysis.","authors":"Zhuojun Xie, Wei Feng, Xiaohong Die, Jinping Hou, Zhenhua Guo, Wei Liu, Yi Wang, Shasha Tian","doi":"10.1186/s12887-025-05695-5","DOIUrl":"https://doi.org/10.1186/s12887-025-05695-5","url":null,"abstract":"<p><strong>Background: </strong>Meckel's diverticulum (MD) is the most common congenital anomaly of the small intestine, and often leads to various complications in children. This study aims to compare the efficacy and safety of single-incision laparoscopic surgery (SILS) and conventional laparoscopic surgery (CLS) in the treatment of MD in children.</p><p><strong>Methods: </strong>Retrospective review of patients who underwent laparoscopic surgery for MD at a tertiary pediatric hospital from February 2017 to February 2023 was conducted with registered of demographic information, preoperative laboratory results, operative findings, and postoperative outcomes. Based on the surgical strategy, patients were classified into SILS and CLS groups. Propensity score matching (PSM) was employed to adjust for confounding factors, resulting in 188 matched pairs. Using PSM, the two groups were compared for baseline differences and postoperative outcomes.</p><p><strong>Results: </strong>Of the 561 patients, the SILS-to-CLS ratio was 301: 260. After one-to-one PSM, results showed that compared with the CLS group, the SILS group had a significantly shorter postoperative hospital stay (P = 0.004), and earlier excretion time and fasting time (P < 0.05). Furthermore, SILS resulted in better scar assessment and higher satisfaction score (both P < 0.05). The two groups had no significant differences in the rates of postoperative complications (P = 0.439) and readmission (P = 0.291). Conversion to open surgery was more common in the SILS group (10.6%) than in the CLS group (6.4%), although this difference was not statistically significant after matching (P = 0.139).</p><p><strong>Conclusion: </strong>Our study aimed to determine the superiority of SILS over CLS in the treatment of pediatric MD. SILS offers distinct advantages over CLS in managing MD in children, including shorter hospital stays and bowel function recovery, without increasing postoperative complications. These findings suggest that SILS may be a preferable approach, warranting its integration into standard clinical practice for MD treatment.</p>","PeriodicalId":9144,"journal":{"name":"BMC Pediatrics","volume":"25 1","pages":"344"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12044976/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143977328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}