BMC Pediatrics最新文献

{"title":"Mortality risk factors in actively resuscitated 22-week preterm infants: a case-control study focusing on NEC and maternal hospitalization.","authors":"Tomonori Kurimoto, Takuya Tokuhisa, Keisuke Ohtsuka, Toshio Harumatsu, Hiroshi Ohashi, Eiji Hirakawa, Takatsugu Maeda, Masato Kamitomo","doi":"10.1186/s12887-025-06178-3","DOIUrl":"10.1186/s12887-025-06178-3","url":null,"abstract":"","PeriodicalId":9144,"journal":{"name":"BMC Pediatrics","volume":"25 1","pages":"788"},"PeriodicalIF":2.0,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12513028/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145257366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding posterior drooling in children and young people with neurodevelopmental disabilities: a parental perspective.","authors":"Lynn B Orriëns, Jan J W van der Burg, Petra Maille-Wisse, Angret de Boer, Frank J A van den Hoogen, Michèl A A P Willemsen, Karen van Hulst, Corrie E Erasmus","doi":"10.1186/s12887-025-06039-z","DOIUrl":"10.1186/s12887-025-06039-z","url":null,"abstract":"<p><strong>Background: </strong>Saliva control problems in children and young people with neurodevelopmental disabilities are classified as anterior drooling (i.e. loss of saliva from the mouth) and posterior drooling (i.e. saliva spillage into the oropharynx). Posterior drooling poses serious health risks, but is often missed or misinterpreted. This study explored how parents perceive its symptoms and impact on daily life.</p><p><strong>Methods: </strong>Semi-structured focus group discussions were conducted with parents of children with posterior drooling, directed toward observable signs and impact on children as well as family. Sessions were recorded, transcribed, and thematically analysed.</p><p><strong>Results: </strong>Three focus group sessions were conducted (total n = 12). Posterior drooling generally manifested across four domains: (1) head and throat, (2) airways, (3) stomach, and (4) whole body. The impact of posterior drooling encompassed effects on children's well-being, social participation, independence, and interference with other conditions. For parents, posterior drooling posed practical, emotional, and social challenges and burdens - such as constant vigilance due to fear of choking, frustration about lack of effective treatment, and limited ability to participate in family or social activities - placing a considerable burden on daily life and caregiving.</p><p><strong>Conclusions: </strong>This qualitative study offers valuable initial insights into how parents characterise posterior drooling, shedding light on crucial information to enhance recognition and diagnosis. The findings underscore the need for earlier detection and identification of posterior drooling symptoms, supported by improved communication between healthcare professionals and families through a shared language that bridges clinical and everyday observations. The extensive impact on children and families also highlights the urgency of providing clearer guidance to parents on managing fluctuating or worsening symptoms, and of developing more comprehensive, tailored care strategies.</p>","PeriodicalId":9144,"journal":{"name":"BMC Pediatrics","volume":"25 1","pages":"789"},"PeriodicalIF":2.0,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12512428/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145257476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reliability and reproducibility of CBCT assessment of craniomaxillary changes before and after treatment for Class III growing patients - a cautious or critical approach.","authors":"XiaoYing Hu, YiYang Zhang, Gary Shun Pan Cheung, RuoNan Sun, FuSheng Dong","doi":"10.1186/s12887-025-06049-x","DOIUrl":"10.1186/s12887-025-06049-x","url":null,"abstract":"<p><strong>Background: </strong>To evaluate reliability and reproducibility of 3-dimensional (3D) assessment of maxillary protraction treatment using voxel-based superimposition of cone-beam computed tomography (CBCT) models of the anterior cranial base in growing patients with skeletal class III malocclusion.</p><p><strong>Methods: </strong>CBCT scans were performed before and after maxillary protraction treatment for Class III malocclusion. Three observers independently constructed 162(27*2*3) 3D virtual models from CBCT scans, which had been reoriented 3D models before treatment to natural head posture, of 27 patients in software. The anterior cranial base was used to register the 3D models pre- and post- treatment. Three observers independently identified 9 landmarks(Including those in the contralateral side)and recorded in three-dimensional coordinates in the 3D models. each observer performed this three times on the pre- and post-treatment model. The mean value of the 3 sets of coordinates at different times was taken as the coordinates for each landmark. The intraobserver reliability and inter-observer reproducibility of the method for craniomaxillary changes were analyzed.</p><p><strong>Results: </strong>The reliability for intraobserver assessments, with ICC > 0.90 for 25 (92.6%) of intraobserver assessments. 24 of 27 (88.9%) cases showed that the accuracy of the measurement method were below 0.3 mm. 21 of the 27 cases showed that the inter-bserver reproducibility errors were below 0.3 mm; only 6 cases (22.2%) showed error ≥ 0.3 mm.</p><p><strong>Conclusions: </strong>The reliability andreproducibility of the method for assessment of maxillary protraction treatment in growing patients with skeletal Class Ⅲmalocclusion were judged to be excellent.</p>","PeriodicalId":9144,"journal":{"name":"BMC Pediatrics","volume":"25 1","pages":"794"},"PeriodicalIF":2.0,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12512949/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145257437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel missense variant at the site of interaction between RLIM and E2 ubiquitin-conjugating enzymes causes Tønne-Kalscheuer syndrome.","authors":"Evelina Siavrienė, Justas Dapkūnas, Živilė Maldžienė, Violeta Mikštienė, Gunda Petraitytė, Eglė Preikšaitienė","doi":"10.1186/s12887-025-06194-3","DOIUrl":"10.1186/s12887-025-06194-3","url":null,"abstract":"","PeriodicalId":9144,"journal":{"name":"BMC Pediatrics","volume":"25 1","pages":"797"},"PeriodicalIF":2.0,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12512490/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145257318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Social equity in Ethiopian infants' breastfeeding and complementary feeding practices: a birth cohort study.","authors":"Amare Tariku, Kassahun Alemu, Joanna Schellenberg, Tanya Marchant, Della Berhanu, Seblewengel Lemma, Atkure Defar, Theodros Getachew, Zewditu Abdissa, Tadesse Guadu, Solomon Shiferaw, Girum Taye, Meseret Zelalem, Lars Åke Persson","doi":"10.1186/s12887-025-06105-6","DOIUrl":"10.1186/s12887-025-06105-6","url":null,"abstract":"","PeriodicalId":9144,"journal":{"name":"BMC Pediatrics","volume":"25 1","pages":"795"},"PeriodicalIF":2.0,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12512986/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145257481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urban-rural disparity in preterm neonatal mortality in China: a retrospective study.","authors":"Yuxi Liu, Leni Kang, Yanna Zou, Xue Yu, Yiyong Su, Chongmei Huang, Juan Liang, Yanping Wang, Chunhua He, Cheng Wan","doi":"10.1186/s12887-025-06042-4","DOIUrl":"10.1186/s12887-025-06042-4","url":null,"abstract":"<p><strong>Background: </strong>The neonatal mortality rate (NMR) is a vital indicator for assessing maternal and child health, and preterm birth is one of the leading causes of neonatal mortality. Since 2010, China has implemented multiple maternal and child health policies aimed at reducing neonatal mortality. However, systematic research on urban-rural disparities in neonatal mortality among preterm births remains relatively scarce. In this study, we analyzed the national and subnational cause-specific death rates of preterm neonates in mainland China during 2010 to 2021 to provide data support for the further elimination of neonatal deaths.</p><p><strong>Methods: </strong>In this retrospective study, we analyzed empirical data on levels and causes of preterm neonatal mortality data from the China Maternal and Child Health Surveillance System to show the cause-specific death rates, birthplaces and treatment levels at the national and subnational levels.</p><p><strong>Results: </strong>From 2010 to 2021, the neonatal mortality rate due to complications of prematurity declined from 289 to 88 per 100,000 live births in rural areas, and from 126 to 41 in urban areas. Although rural rates remained higher, the absolute gap narrowed over time. According to the definitions used in the Maternal and Child Health Surveillance System (MCHSS), live births were registered only for neonates with signs of life who were born at ≥ 28 weeks of gestation or had a birth weight > 1000 g (if gestational age was unavailable), mortality was consistently highest among neonates born at 28 to 31 gestational weeks in both settings. In 2021, 95.5% of preterm neonates in urban areas were born at provincial-level hospitals, compared to 60.2% in rural areas. The proportion of preterm neonates diagnosed at county-level facilities in rural areas dropped from 46.7% to 21.8%, while in urban areas it fell from 6.5% to 2.3%.</p><p><strong>Conclusions: </strong>This study demonstrates persistent urban-rural disparities in cause-specific mortality and gestational age distribution among preterm neonates. Findings may help local governments develop targeted strategies to further reduce overall neonatal mortality.</p>","PeriodicalId":9144,"journal":{"name":"BMC Pediatrics","volume":"25 1","pages":"793"},"PeriodicalIF":2.0,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12512810/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145257386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of exercise interventions on physical recovery in paediatric cancer patients and survivors: a meta-analysis.","authors":"Bo Yeon Kim, Hye Yeon Kim, Dong Hoon Lee, Justin Y Jeon","doi":"10.1186/s12887-025-06136-z","DOIUrl":"10.1186/s12887-025-06136-z","url":null,"abstract":"","PeriodicalId":9144,"journal":{"name":"BMC Pediatrics","volume":"25 1","pages":"792"},"PeriodicalIF":2.0,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12512279/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145257373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of biological, socioeconomic, and environmental factors with child development at two years of age in Bangladesh, Pakistan, and Tanzania: results from the AMANHI-ACT study.","authors":"Ambreen Nizar, Rasheda Khanam, Jamila Khalfan Ali, Muhammad Imran Nisar, Fahmida Tofail, Bishara Ali Alawi, Nadia Ansari, Salahuddin Ahmed, Usha Dhingra, Fariha Shaheen, Abrarul Haque Asif, Arup Dutta, Muhammad Farrukh Qazi, Sayedur Rahman, Mayassa Aly, Usma Mehmood, Nabidul Haque Chowdhury, Fahad Aftab, Shahira Shahid, Mohammod Shahidullah, Fatma M Kabole, Farzana Begum, Pamela J Surkan, Anupama Verma, Alexander Manu, Sachiyo Yoshida, Rajiv Bahl, Sunil Sazawal, Abdullah H Baqui, Fyezah Jehan","doi":"10.1186/s12887-025-06060-2","DOIUrl":"10.1186/s12887-025-06060-2","url":null,"abstract":"<p><strong>Background: </strong>The first 1,000 days of life, spanning pregnancy to two years, are critical for development. We investigated the association of maternal, socioeconomic, environmental, nutritional, and childhood characteristics with cognitive, motor, and language development at two years of age.</p><p><strong>Methods: </strong>The AMANHI-ACT study enrolled pregnant women between 8 and 19 weeks of gestation from Bangladesh, Pakistan, and Tanzania. Data was collected on sociodemographic factors, maternal BMI and co-morbidities during pregnancy, and weight and gestational age at birth. Child characteristics included vaccination history, infections, and physical growth at predefined intervals up to two years. Child development at two years was assessed using the Bayley Scales of Infant and Toddler Development Third Edition (Bayley-III). The home environment was assessed using the Home Observation for Measurement of the Environment Infant-Toddler (HOME-IT) tool. We performed linear regression and reported site-adjusted regression coefficients with 95% confidence intervals.</p><p><strong>Results: </strong>We assessed 3,062 children at two years of age to identify factors associated with their cognitive, language, and motor development scores. Cognitive scores were significantly lower among children whose mothers had no formal education (Adjusted coefficient = -3.8; 95% CI: -5.8, -1.8) and those who had not received any vaccinations (Adjusted coefficient = -6.0; 95% CI: -9.3, -2.6). Language development was similarly affected: children with mothers who had no education (Adjusted coefficient = -4.7; 95% CI: -6.8, -2.5) or only primary-level education (Adjusted coefficient = -4.5; 95% CI: -6.5, -2.5) showed markedly lower scores. Language scores were also reduced in children whose fathers had no education (Adjusted coefficient = -2.4; 95% CI: -4.2, -0.5) or only primary education (Adjusted coefficient = -2.4; 95% CI: -4.1, -0.6). For motor development, children who were stunted (Adjusted coefficient = -2.2; 95% CI: -2.9, -1.4), wasted (Adjusted coefficient = -2.8; 95% CI: -4.3, -1.4), or unvaccinated (Adjusted coefficient = -4.7; 95% CI: -8.0, -1.4) at two years exhibited significantly lower scores.</p><p><strong>Conclusion: </strong>Preterm births, vaccination history, parental education, and physical growth significantly affected the first 1000 days of child development, thus identifying areas for targeted intervention to optimize long-term health outcomes in LMICs.</p>","PeriodicalId":9144,"journal":{"name":"BMC Pediatrics","volume":"25 1","pages":"785"},"PeriodicalIF":2.0,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12505821/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145249800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Caring behavior: perspectives from nurses and parents of hospitalized children.","authors":"Mehri Ansariniaki, Seifollah Alaei, Mojtaba Khoshdast Kakhki, Majid Mirmohammadkhani","doi":"10.1186/s12887-025-06153-y","DOIUrl":"10.1186/s12887-025-06153-y","url":null,"abstract":"<p><strong>Background: </strong>The active presence of parents during the care and treatment of children in the hospital serves a crucial role in care provision. Considering the perspective on caring behavior from both nurses and clients is essential for planning and enhancing the quality of nursing care. This study assessed nurses' and parents' perceptions of nursing care.</p><p><strong>Method: </strong>A cross-sectional descriptive study was conducted between December 2022 and June 2023 at a tertiary pediatric referral hospital in Iran, involving 115 nurses and 115 parents. Demographic data and responses to Wolff's Caring Behavior Questionnaire were collected during morning and evening shifts, with questionnaires retrieved at the end of each shift. Data were analyzed using SPSS version 25.</p><p><strong>Result: </strong>Nurses' perception yielded an average caring behavior's score of 234.37±15.25, whereas parents' perception averaged 213.01±43.7. A statistically significant difference was observed between nurses' and parents' average scores of caring behavior perception (p<0.001). The highest average scores for caring behavior perception dimensions were associated with attentiveness to others' experiences and professional knowledge and skills among nurses and parents. A statistically significant difference (p<0.001) existed between nurses and parents across all domains. Also, age, insurance coverage of families, and working stability of nurses exhibited significant associations with their perception of caring behavior.</p><p><strong>Conclusion: </strong>Although nurses and parents reported above-average caring behavior scores were above average, nurses exhibited significantly higher levels. Misalignment in parents' perceptions may stem from specific familial challenges influencing their interpretation of nursing care. Hospital and nursing leadership should consider strategies to strengthen caring behaviors among nurses. Enhancing role clarity may align service recipients' expectations with professional responsibilities. Furthermore, improving nurses' job stability is essential to support consistent and effective caring behavior.</p>","PeriodicalId":9144,"journal":{"name":"BMC Pediatrics","volume":"25 1","pages":"784"},"PeriodicalIF":2.0,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12505758/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145249836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electric scooter related injuries among children: a single institutional experience.","authors":"Ali Abu-Kishk, Eran Kozer, Rony Beeri Berkowiz, Meital Ben-Ari, Ibrahim Abu-Kishk","doi":"10.1186/s12887-025-06181-8","DOIUrl":"10.1186/s12887-025-06181-8","url":null,"abstract":"","PeriodicalId":9144,"journal":{"name":"BMC Pediatrics","volume":"25 1","pages":"787"},"PeriodicalIF":2.0,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12505761/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145249870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}