{"title":"A Comparison of Amino Acid-Based, Hydrolyzed, and Soy-Based Formulas on Growth of Pediatric Patients with Cow's Milk Allergy: A Systematic Review and Meta-Analysis of Clinical Trials.","authors":"Artemiss Mirdar Harijani, Somaye Fatahi, Nathalia Sernizon Guimarães, Farzad Shidfar","doi":"10.1089/bfm.2024.0252","DOIUrl":"10.1089/bfm.2024.0252","url":null,"abstract":"<p><p><b><i>Background:</i></b> Some studies have explored the effects of amino acid-based formulas (AAF), extensively hydrolyzed formulas (EHF), and soy-based formulas (SF) on growth indices, weight-for-age z-scores, length-for-age z-scores, and weight in children with cow's milk allergy (CMA). <b><i>Aims:</i></b> This review aimed to evaluate and differentiate the effectiveness of AAF, EHF, and SF on growth parameters in children with CMA. <b><i>Methods:</i></b> A systematic review was conducted in three databases-PubMed, Web of Science, and Scopus-up to March 2023 to identify eligible studies. Eight articles were analyzed in this study. Effect sizes were reported as weighted mean difference with 95% confidence intervals (CI). Statistical heterogeneity between studies was assessed using Cochran's Q-test. The risk of bias was evaluated using the ROBINS-I tool. <b><i>Results:</i></b> A total of eight studies, encompassing 469 participants, met the inclusion criteria. The meta-analysis demonstrated a significant positive effect of the AAF and EHF on weight and weight-for-age z-scores, while no significant changes were observed for length-for-age z-scores. Furthermore, pooled effect sizes indicated that AAF had a more pronounced impact in weight-for-age z-scores (+0.30) compared with EHF (+0.25). Soy-based formulas had negligible effects on growth parameters. <b><i>Conclusion:</i></b> The findings suggest that AAF and EHF are more effective in improving growth parameters, particularly weight-for-age z-scores, in children with CMA compared with SF. Among the formulas studied, AAF showed the greatest positive impact on weight-for-age z-scores. These results highlight the importance of formula selection for optimizing growth outcomes in children with CMA.</p>","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":"288-295"},"PeriodicalIF":2.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143977358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Breastfeeding MedicinePub Date : 2025-05-01Epub Date: 2025-01-21DOI: 10.1089/bfm.2024.0263
Michele K Griswold, Sybil L Crawford, Sharina D Person, Lynn Rosenberg, Julie R Palmer, Yvette C Cozier
{"title":"Neighborhood Socioeconomic Status and Breastfeeding Initiation and Duration Among Primiparous Black Women.","authors":"Michele K Griswold, Sybil L Crawford, Sharina D Person, Lynn Rosenberg, Julie R Palmer, Yvette C Cozier","doi":"10.1089/bfm.2024.0263","DOIUrl":"10.1089/bfm.2024.0263","url":null,"abstract":"<p><p><b><i>Background:</i></b> Social determinants of health account for racial inequities in breastfeeding rates in the United States. There is a gap in the role of neighborhood socioeconomic status (NSES) as it relates to breastfeeding disparities. <b><i>Methods:</i></b> Using longitudinal data from the Black Women's Health Study, we assessed associations of NSES with breastfeeding initiation and duration in a cohort of primiparous U.S. Black women. We also explored associations within strata of important economic indicators, including education, occupation, and marital status. <b><i>Results:</i></b> Breastfeeding initiation (<i>n</i> = 2,705) increased with NSES quartile, from 75.2% in the lowest quartile to 88.3% in the highest quartile (<i>p</i> < 0.0001). Compared with women living in the highest NSES quartile, those in the lowest quartile had a 41% (odds ratio: 0.59 [95% confidence interval: 0.43, 0.81]) decreased odds of initiating breastfeeding. For breastfeeding duration (<i>n</i> = 2,172), women residing in NSES quartiles 1-3 were significantly less likely (<i>p</i> < 0.0001) to breastfeed (44.4%) for 6+ months compared with those living in the highest quartile (62.8%). Adjusted relative risks for those in quartiles 1-3 compared with 4 (highest) were 0.63 (0.45, 0.87), 0.50 (0.37, 0.68), and 0.64 (0.47, 0.86), respectively (<i>p</i> = 0.0001). There was no statistically significant evidence of effect modification by education, occupation, marital status, and region (<i>P</i><sub>interaction</sub> = >0.05). <b><i>Conclusion:</i></b> Living in a lower NSES environment was associated with reduced breastfeeding initiation and duration compared with a higher NSES environment. Research is needed to understand the mechanisms by which neighborhood-level factors influence breastfeeding initiation and duration for Black women in the United States.</p>","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":"310-319"},"PeriodicalIF":2.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143000168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Maternity Care Practices and Their Role in U.S. Breastfeeding Disparities.","authors":"Luis Seoane Estruel, Tatiana Andreyeva","doi":"10.1089/bfm.2024.0368","DOIUrl":"https://doi.org/10.1089/bfm.2024.0368","url":null,"abstract":"<p><p><b><i>Introduction:</i></b> Breastfeeding provides substantial health benefits for both children and mothers; yet the U.S. rates remain suboptimal, with disparities shaped by structural, social, and policy factors. This study examines how the U.S. hospital maternity care practices influence breastfeeding initiation, with particular attention to their impact across different population groups. <b><i>Methods:</i></b> We analyzed cross-sectional county-level variations in hospital maternity care quality and breastfeeding initiation from 2017 to 2022 using data from the National Vital Statistics System and the Maternity Practices in Infant Nutrition and Care (mPINC) surveys. We employed a linear probability model to assess these relationships. <b><i>Results:</i></b> Higher county mPINC scores are significantly associated with increased breastfeeding initiation, with each additional point linked to a 0.10 percentage point (pp) increase (<i>p</i> < 0.001). This association varies by race/ethnicity. Each additional mPINC point corresponds to a 0.25 pp increase for non-Hispanic Black mothers (<i>p</i> < 0.001) and a 0.14 pp increase for non-Hispanic American Indian/Alaska Native mothers (<i>p</i> < 0.001), approximately three and two times higher, respectively, than the increase for non-Hispanic White mothers. The effect of better maternity practices also differs by county type, with a 0.08 pp increase in metro areas (<i>p</i> < 0.001) and a 0.17 pp increase in nonmetro areas (<i>p</i> < 0.001). <b><i>Conclusions:</i></b> Higher quality hospital maternity care practices are associated with increased breastfeeding initiation, particularly among population groups with historically lower breastfeeding rates. Enhancing maternity care policies and practices may help reduce long-standing breastfeeding disparities.</p>","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143964980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antipsychotics and Breastfeeding.","authors":"Philip O Anderson","doi":"10.1089/bfm.2025.0086","DOIUrl":"https://doi.org/10.1089/bfm.2025.0086","url":null,"abstract":"","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143971890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Susanna Foxworthy Scott, Julie Searcy, Izzi Jordan
{"title":"\"Why Is There Not a Doctor that Knows Anything About This Part of My Body?\" Patient Perspectives on Chronic Lactation Insufficiency.","authors":"Susanna Foxworthy Scott, Julie Searcy, Izzi Jordan","doi":"10.1089/bfm.2025.0018","DOIUrl":"https://doi.org/10.1089/bfm.2025.0018","url":null,"abstract":"<p><p><b><i>Introduction:</i></b> Although exclusive breastfeeding is recommended for the first six months of life, many lactating individuals discontinue due to low milk supply, a condition sometimes referred to as chronic lactation insufficiency (CLI). Affecting an estimated 5-15% of lactating individuals, CLI can stem from both extrinsic factors (e.g., infant feeding challenges) and intrinsic ones (e.g., endocrine or metabolic disorders). This qualitative study explored the lived experiences of individuals with CLI and their interactions with healthcare providers (HCPs). <b><i>Methods:</i></b> In-depth, semi-structured interviews were conducted with 30 individuals who self-reported experiencing low milk supply, were 18 or older, and were members of the \"IGT and Low Milk Supply Support Group\" on Facebook, which has approximately 10,700 members. Data were analyzed using phronetic iterative analysis which is a cyclical, reflexive coding approach that emphasizes practical reasoning. <b><i>Results:</i></b> Participants reported significant challenges, including: (1) not being believed or taken seriously; (2) facing discrepancies between providers that led to fragmented care; and (3) experiencing a lack of knowledge from HCPs, including lactation consultants. Many described actively seeking a diagnosis and meaningful support but instead receiving inconsistent advice and little to no diagnostic insight into their condition. <b><i>Conclusions:</i></b> These findings highlight the urgent need for improved education and training among HCPs to address the complex realities of CLI. They also point to the importance of advancing personalized approaches to breastfeeding support and expanding research to determine causes and diagnostics for low milk supply. By centering patient voices, this study identifies critical gaps in care and communication that prevent effective support for those navigating CLI.</p>","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143779074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Breastfeeding MedicinePub Date : 2025-04-01Epub Date: 2025-01-02DOI: 10.1089/bfm.2024.0337
Mariela V Cortez, Georgina N Marchiori, Manuela Jubete, Lorena A Lázaro, María I López Merzbacher, Elio A Soria
{"title":"Impact of Freezing, Storage, and Pasteurization on Nutritional Components and Redox Biomarkers in Human Milk Donations.","authors":"Mariela V Cortez, Georgina N Marchiori, Manuela Jubete, Lorena A Lázaro, María I López Merzbacher, Elio A Soria","doi":"10.1089/bfm.2024.0337","DOIUrl":"10.1089/bfm.2024.0337","url":null,"abstract":"<p><p><b><i>Objective:</i></b> This study evaluates the impact of various processing steps in the human milk (HM) donation chain on nutritional composition and oxidative biomarkers, specifically focusing on triacylglycerols, glucose, polyphenols, and lipid peroxides. <b><i>Materials and Methods:</i></b> A total of 68 HM samples were collected from the Human Milk Bank of Córdoba (Argentina) between 2022 and 2023. The effects of storage and pasteurization using the Holder method were assessed. Biochemical analyses were conducted to measure nutrient levels and oxidative markers. Statistical analyses included time-related modeling and paired <i>t</i> tests to evaluate the effects of storage and pasteurization, respectively. <b><i>Results:</i></b> Triacylglycerol levels were markedly reduced during home storage (<i>R</i><sup>2</sup> = 0.802, <i>p</i> = 0.0210), whereas glucose, lipid peroxides, and polyphenols remained stable (<i>R</i><sup>2</sup> < 0.3, <i>p</i> > 0.05). Storage at the bank did not affect these biomarkers (<i>R</i><sup>2</sup> < 0.25, <i>p</i> > 0.05). Pasteurization resulted in increased glucose levels (<i>p</i> = 0.0292) and decreased triacylglycerol levels (<i>p</i> = 0.0073), along with a significant reduction in lipid peroxides (<i>p</i> < 0.0001). <b><i>Conclusions:</i></b> The findings indicate that home storage conditions significantly diminish triacylglycerol levels in HM, highlighting the need for improved storage practices among donors. Pasteurization provides antioxidant benefits by reducing lipid peroxides while maintaining nutritional integrity.</p>","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":"261-266"},"PeriodicalIF":2.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142913574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Breastfeeding MedicinePub Date : 2025-04-01Epub Date: 2024-12-10DOI: 10.1089/bfm.2024.0123
Negarin Akbari, Birsen Mutlu, Homeira Khoddam
{"title":"Comparison of the Effect of Maternal Breast Milk Odor, Facilitated Tucking, and Nonnutritive Sucking Applied to Preterm Neonates During Heel Stick on Pain and Physiological Parameters: A Randomized Controlled Trial.","authors":"Negarin Akbari, Birsen Mutlu, Homeira Khoddam","doi":"10.1089/bfm.2024.0123","DOIUrl":"10.1089/bfm.2024.0123","url":null,"abstract":"<p><p><b><i>Background:</i></b> Preterm infants in the neonatal intensive care unit (NICU) frequently undergo painful procedures, which can lead to both short-term and long-term complications, including potential mortality. Effective pain management is crucial in this context. Although numerous studies have explored non-pharmacological pain relief methods for preterm infants, no research has simultaneously compared the effects of maternal breast milk odor, facilitated tucking, and nonnutritive sucking. <b><i>Aim:</i></b> This study aims to comparatively investigate the efficacy of nonnutritive sucking, facilitated tucking, and maternal breast milk odor in reducing pain in preterm neonates during heel sticks. <b><i>Methods:</i></b> A randomized controlled trial was conducted in a tertiary-level NICU with 144 preterm neonates (gestational age 31-36 weeks) requiring heel sticks. The infants were randomly assigned to four groups: control, nonnutritive sucking, facilitated tucking, and maternal breast milk odor. Pain and physiological parameters were assessed through video recordings of the procedures and scored at 1-minute intervals using the Premature Infant Pain Profile and Data Evaluation Form. Data were collected at baseline and at 1, 2, and 3 minutes before, during, and after the heel stick. <b><i>Results:</i></b> The study found significant effects of the interventions on physiological parameters and pain (heart rate: <i>F</i> = 7.5, <i>p</i> < 0.001; oxygen saturation: <i>F</i> = 16.39, <i>p</i> < 0.001; respiratory rate: <i>F</i> = 6.56, <i>p</i> < 0.001; pain: <i>F</i> = 61.45, <i>p</i> < 0.001). Facilitated tucking resulted in significantly lower pain scores (6.61 ± 1.44) compared with the control group (14.22 ± 3.61), maternal breast milk odor (12.22 ± 3.08), and nonnutritive sucking (10.41 ± 1.71) (<i>p</i> < 0.001). <b><i>Conclusions:</i></b> All interventions demonstrated effectiveness in maintaining physiological stability and alleviating pain. Nevertheless, the intervention identified as most effective in reducing pain was facilitated tucking group.</p>","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":"244-255"},"PeriodicalIF":2.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142799384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Breastfeeding MedicinePub Date : 2025-04-01Epub Date: 2025-02-24DOI: 10.1089/bfm.2025.0028
Elien Rouw
{"title":"Academy of Breastfeeding Medicine Conferences-A Bonding Experience to Breastfeeding.","authors":"Elien Rouw","doi":"10.1089/bfm.2025.0028","DOIUrl":"10.1089/bfm.2025.0028","url":null,"abstract":"","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":"284"},"PeriodicalIF":2.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Breastfeeding Challenges Experienced by Mothers Following Multiple Births-a Systematic Review and Meta-Synthesis of Quantitative, Qualitative, and Mixed-Methods Studies.","authors":"Geeta Bhardwaj, Moonjelly Vijayan Smitha, Prasuna Jelly, Shine Stephen, Jessica Eustace- Cook, Sunita Panda","doi":"10.1089/bfm.2024.0207","DOIUrl":"10.1089/bfm.2024.0207","url":null,"abstract":"<p><p><b><i>Background:</i></b> Breastfeeding is vital for infant nutrition, especially for multiple babies (twins) born prematurely, yet breastfeeding rates among mothers of twins are lower compared with mothers of singleton babies. This review presents a synthesis of research findings on breastfeeding challenges experienced by mothers following twins' births. <b><i>Methods:</i></b> The electronic databases of CINAHL, MEDLINE, PsycINFO, EMBASE, and Web of Science were systematically searched in August 2023. All eligible quantitative, qualitative, and mixed-methods studies reported on breastfeeding challenges experienced by mothers of twins were included. The review adhered to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and followed Lucas et al.'s framework for thematic synthesis. Two reviewers independently screened all studies by title, abstract, and full text. The methodological quality of studies was independently assessed by two reviewers using the Joanna Briggs Institute critical appraisal tool and mixed-methods appraisal tool based on study design. <b><i>Results:</i></b> The review included 16 studies: quantitative (<i>n</i> = 5), qualitative (<i>n</i> = 8), and mixed methods (<i>n</i> = 3), published between 1980 and 2022, involving 3,351 mothers from 16 countries. Three main themes were generated as follows: (1) transitioning to a new role, finding the balance between self and the newborns' needs; (2) the inevitability of emotional challenges; and (3) navigating support and information. <b><i>Conclusion:</i></b> The integrated findings of quantitative, qualitative, and mixed-methods studies on challenges experienced by mothers of twins will have scope for researchers to address the challenges through tailored intervention, education, and support and can help health care professionals revisit policy and practices to extend support services for mothers of twins beyond the initial postpartum and to the community for improving breastfeeding practices among mothers following multiple births.</p>","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":"219-230"},"PeriodicalIF":2.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142920472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}