Breastfeeding Medicine最新文献_第4页

The Association Between Maternal Psychological Health and Human Milk Oligosaccharide Composition. 产妇心理健康与母乳低聚糖成分之间的关系

IF 2.7 3区医学

Breastfeeding Medicine Pub Date : 2024-09-17 DOI: 10.1089/bfm.2024.0179

Hannah Riedy,Kerri Bertrand,Christina Chambers,Gretchen Bandoli

{"title":"The Association Between Maternal Psychological Health and Human Milk Oligosaccharide Composition.","authors":"Hannah Riedy,Kerri Bertrand,Christina Chambers,Gretchen Bandoli","doi":"10.1089/bfm.2024.0179","DOIUrl":"https://doi.org/10.1089/bfm.2024.0179","url":null,"abstract":"Background and Objective: Human milk oligosaccharides (HMOs) are carbohydrates abundant in human breast milk. Their composition varies widely among women, and prior research has identified numerous factors contributing to this variation. However, the relationship between maternal psychological health and HMO levels is currently unknown. Thus, our objective was to identify whether maternal stress, anxiety, or depressive symptoms are associated with HMOs. Methods: Data originated from 926 lactating individuals from the UC San Diego Human Milk Biorepository. Nineteen prevalent HMOs were assayed using high-performance liquid chromatography. Participants self-reported measures of the Edinburgh Postnatal Depression Scale (n = 495), State-Trait Anxiety Inventory S-Scale (n = 486), and/or Perceived Stress Scale (n = 493) within 60 days of their milk collection; their results were categorized using standard screening cutoffs. HMOs were assessed individually and grouped by principal component analysis (PCA), and associations with maternal psychological symptoms were analyzed using multivariable linear regression adjusted for covariates. Results: After Bonferroni correction (p < 0.002), the following HMOs significantly varied with maternal psychological distress in multivariate analysis: lacto-N-fucopentaose III (LNFP III) and lacto-N-hexaose (LNH) among Secretors with depressive symptoms and difucosyllactose (DFLac), LNFP III, and disialyl-LNH (DSLNH) among Secretors with stress. In PCA, depressive symptoms and stress were associated with one principal component among Secretors. No HMOs varied with anxiety symptoms. Conclusions: Several HMOs varied with maternal depressive symptoms and stress, suggesting a relationship between maternal psychological health and breast milk composition. Additional studies are needed to determine the impact of this variation on infant health.","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142252146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Holy Grail of an Efficacious Galactagogue. 高效促性腺激素的圣杯

IF 2.7 3区医学

Breastfeeding Medicine Pub Date : 2024-09-17 DOI: 10.1089/bfm.2024.0280

Arthur I Eidelman

引用次数: 0

Minimal Transfer of Atorvastatin and Its Metabolites in Human Milk: A Case Series. 阿托伐他汀及其代谢物在母乳中的最小转移：一个案例系列。

IF 2.1 3区医学

Breastfeeding Medicine Pub Date : 2024-09-13 DOI: 10.1089/bfm.2024.0258

Levi Campbell, Kristin Huseman, Kaytlin Krutsch, Palika Datta

{"title":"Minimal Transfer of Atorvastatin and Its Metabolites in Human Milk: A Case Series.","authors":"Levi Campbell, Kristin Huseman, Kaytlin Krutsch, Palika Datta","doi":"10.1089/bfm.2024.0258","DOIUrl":"https://doi.org/10.1089/bfm.2024.0258","url":null,"abstract":"Background: Statins are historically contraindicated during breastfeeding due to theoretical concerns of disruptions in infant development from drug exposure and nutritional changes in milk. Breastfeeding mothers requiring statins often discontinue statins or postpone treatment until breastfeeding cessation, contributing to delays in treatment up to 14 years. This study aims to determine the transfer of atorvastatin and its active metabolites into human milk and evaluate the infant's risk of drug exposure. Materials and Methods: Milk samples and health information were released from the InfantRisk Human Milk Biorepository for three women taking 20 mg, 40 mg, and 80 mg of atorvastatin daily at steady state conditions. The concentration of atorvastatin (AT) and its active metabolites, ortho-hydroxy AT (2OH AT) and para-hydroxy AT (4OH AT), was quantified in timed milk samples using liquid chromatography-mass spectrometry. Results: The highest absolute infant dose of AT was 0.00027 mg/kg/day, and the highest weight-adjusted relative infant dose of the combined analytes was 0.09%, far below established thresholds for infant safety. Milk cholesterol levels were within previously established norms in the range of 10 mg/dL. The mothers reported no adverse outcomes in the two exposed infants. Conclusions: The transfer of atorvastatin and its metabolites was exceedingly low. While the impact on milk composition in states of hyperlipidemia (whether treated or untreated) is not well understood, it is unlikely that the drug in the milk would be present in clinically significant levels to adversely affect a breastfed infant.","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142280262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fat Content and Energy Calculation in Pasteurized Human Milk: Comparison Between Infrared Analysis and Creamatocrit Method. 巴氏杀菌人乳中的脂肪含量和能量计算：红外分析法与奶油比容法的比较

IF 2.7 3区医学

Breastfeeding Medicine Pub Date : 2024-09-12 DOI: 10.1089/bfm.2024.0249

Nerli Pascoal Andreassa,Fabiola Isabel Suano-Souza,Roseli Oselka Saccardo Sarni

{"title":"Fat Content and Energy Calculation in Pasteurized Human Milk: Comparison Between Infrared Analysis and Creamatocrit Method.","authors":"Nerli Pascoal Andreassa,Fabiola Isabel Suano-Souza,Roseli Oselka Saccardo Sarni","doi":"10.1089/bfm.2024.0249","DOIUrl":"https://doi.org/10.1089/bfm.2024.0249","url":null,"abstract":"Aims: This study aimed to analyze and compare the quantity of energy and fat using the infrared analysis and creamatocrit method in pasteurized human milk (HM) samples. Methods: This cross-sectional study analyzed 1,858 pasteurized human samples from 317 mothers at a single center. Infrared transmission spectrophotometry (Miris, Human Milk Analyser [HMA], Uppsala, Sweden) and the creamatocrit method were used to evaluate the quantity of energy and fat in pasteurized HM samples. Results: The average age of donor mothers was 29.7 ± 5.1 years, and the median duration of lactation was 22 days (interquartile range [IQ]: 7.7-59.2). Full-term births were observed in 196 (95.1%) of the women. The values of energy (difference: +8.96 kcal/dL, 95% CI: 8.52-9.44 kcal/dL; p < 0.001) and fat (difference: +0.40 g/dL, 95% CI: 0.35-0.45 g/dL; p < 0.001) in HM samples obtained by Miris were higher than those by the creamatocrit method. The energy calculated and the fat measured by Miris in the HM samples correlated moderately and directly with the obtained by creamatocrit (fat, r = 0.585; p < 0.001 and energy, r = 0.591; p < 0.01). The linear regression, adjusted for maternal age and lactation time, showed that the energy values calculated by creamatocrit were directly associated with those of Miris (energy kcal/dL = 38.43 + [0.516 × kcal/dL of creamatocrit]). Conclusion: The energy and fat quantity of pasteurized HM samples obtained by the creamatocrit and infrared methods were significantly correlated. However, the values calculated by the creamatocrit method were significantly lower than those by the infrared analyzer.","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142194042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bloody Colostrum Is Not a Rusty Pipe Phenomenon: Medical Terminology Should Refect Accuracy and Respect for the Maternal Body. 带血初乳并非锈管现象：医学术语应体现准确性和对产妇身体的尊重。

IF 2.7 3区医学

Breastfeeding Medicine Pub Date : 2024-09-12 DOI: 10.1089/bfm.2024.0260

Katarzyna Wszołek,Stanisław Przewoźny,Adrianna Nowek,Angelika Odor,Paulina Małyszka Hoffmann,Marcin Przybylski,Jakub Żurawski,Małgorzata Pięt,Maciej Wilczak

引用次数: 0

Academy of Breastfeeding Medicine Position Statement: Breastfeeding in Emergencies. 母乳喂养医学学会立场声明：紧急情况下的母乳喂养。

IF 2.7 3区医学

Breastfeeding Medicine Pub Date : 2024-09-01 DOI: 10.1089/bfm.2024.84219.bess

Melissa Bartick,Deena R Zimmerman,Zaharah Sulaiman,Amal El Taweel,Fouzia AlHreasy,Lina Barska,Anastasiia Fadieieva,Sandra Massry,Nan Dahlquist,Michal Mansovsky,Karleen Gribble

{"title":"Academy of Breastfeeding Medicine Position Statement: Breastfeeding in Emergencies.","authors":"Melissa Bartick,Deena R Zimmerman,Zaharah Sulaiman,Amal El Taweel,Fouzia AlHreasy,Lina Barska,Anastasiia Fadieieva,Sandra Massry,Nan Dahlquist,Michal Mansovsky,Karleen Gribble","doi":"10.1089/bfm.2024.84219.bess","DOIUrl":"https://doi.org/10.1089/bfm.2024.84219.bess","url":null,"abstract":"Background: During emergencies, including natural disasters and armed conflict, breastfeeding is critically important. Breastfeeding provides reliable nutrition and protection against infectious diseases, without the need for clean water, feeding implements, electricity, or external supplies. Key Information: Protection, promotion, and support of breastfeeding should be an integral part of all emergency preparedness plans. Breastfeeding specialists should be part of plan development. Emergency protocols should include breastfeeding specialists among emergency relief personnel, provide culturally sensitive environments for breastfeeding, and prioritize caregivers of infants in food/water distribution. Emergency relief personnel should be aware that dehydration and missed feedings can impact milk production, but stress alone does not. Emergency support should focus on keeping mothers and infants together and providing private and/or protected spaces for mothers to breastfeed or express milk. Emergency support should also focus on rapidly identifying mothers with breastfeeding difficulties and breastfeeding mothers and infants who are separated, so their needs can be prioritized. Breastfeeding support should be available to all women experiencing difficulties, including those needing reassurance. Nonbreastfed infants should be identified as a priority group requiring support. Relactation, wet-nursing, and donor milk should be considered for nonbreastfed infants. No donations of commercial milk formula (CMF), feeding bottles or teats, or breast pumps should be accepted in emergencies. The distribution of CMF must be highly controlled, provided only when infants cannot be breastfed and accompanied by a comprehensive package of support. Recommendations: Protecting, promoting, and supporting breastfeeding should be included in all emergency preparedness planning and in training of personnel.","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142224970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Impact of the "Doing-the-Month" Practice in Taiwanese Postpartum Women: Hot Food Consumption and Draft Exposure Increase Risk for Breast Engorgement. 台湾产后妇女 "做月子 "习俗的影响：食用热食和接触草稿会增加乳房肿胀的风险。

IF 2.1 3区医学

Breastfeeding Medicine Pub Date : 2024-09-01 Epub Date: 2024-07-26 DOI: 10.1089/bfm.2024.0175

Shuo-Wen Hung, Ming Ho, Hsun-Ming Chang, Shan-Yu Su

引用次数: 0

The Effect of Breast Milk from Different Lactation Stages on in Vitro Wound Healing. 不同哺乳期的母乳对体外伤口愈合的影响

IF 2.1 3区医学

Breastfeeding Medicine Pub Date : 2024-09-01 Epub Date: 2024-06-10 DOI: 10.1089/bfm.2024.0099

Cigdem Aydin Acar, Suray Pehlivanoglu, Sukriye Yesilot, Halil Ibrahim Tasdemir

{"title":"The Effect of Breast Milk from Different Lactation Stages on in Vitro Wound Healing.","authors":"Cigdem Aydin Acar, Suray Pehlivanoglu, Sukriye Yesilot, Halil Ibrahim Tasdemir","doi":"10.1089/bfm.2024.0099","DOIUrl":"10.1089/bfm.2024.0099","url":null,"abstract":"Objective: Wound healing is a complex and dynamic process essential for restoring tissue integrity and homeostasis. It is thought that breast milk contributes positively to the wound healing process, thanks to the components it contains. The aim of this study is to compare the effects of breast milk on the wound healing process at different lactation stages and to evaluate the underlying mechanism(s). Materials and Methods: The effects of breast milk from different lactation stages (colostrum, transitional, and mature milk) on wound healing were determined by in vitro scratch assay in L929 fibroblast cells. 2,2-Diphenyl-1-picrylhydrazyl (DPPH), total oxidant, and antioxidant capacity were used to confirm antioxidant effects. The effect of breast milk on netrin-1 levels in L929 cells was elucidated by ELISA. Results: Breast milk at different lactation stages promoted wound healing. While the wound closure percentage was determined as 48.7% in the control group, this rate was determined to be the highest at 81.6% in the mature milk group (p:0.0002). The free radical scavenging capacity of colostrum, transitional, and mature milk with DPPH was determined as 49.69%, 60.64%, and 80.85%, respectively, depending on the lactation stages. Netrin-1 levels detected by ELISA were determined as 490.1 ± 6.5 pg/mL in the control group, while the lowest level was determined as 376.6 ± 4.5 pg/mL in mature milk (p:0.0003). Conclusions: Breast milk, especially mature milk, promoted wound healing on L929 cells by suppressing netrin-1 levels and scavenging free radicals.","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141295524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cerebral Synchronization Between Mothers and Their Newborns During Breastfeeding. 母乳喂养期间母亲与新生儿之间的大脑同步。

IF 2.1 3区医学

Breastfeeding Medicine Pub Date : 2024-09-01 Epub Date: 2024-07-26 DOI: 10.1089/bfm.2023.0307

Stefano Bembich, Elena Castelpietra, Jenny Bua, Enrica Causin, Chiara Pavan, Francesca Marrazzo, Laura Travan

{"title":"Cerebral Synchronization Between Mothers and Their Newborns During Breastfeeding.","authors":"Stefano Bembich, Elena Castelpietra, Jenny Bua, Enrica Causin, Chiara Pavan, Francesca Marrazzo, Laura Travan","doi":"10.1089/bfm.2023.0307","DOIUrl":"10.1089/bfm.2023.0307","url":null,"abstract":"Introduction: Breastfeeding is a fundamental biological function in mammals, allowing the progeny to develop in a physiological way. A physical and emotional dialog between mothers and offspring during breastfeeding has been described as part of the attachment relationship, and a synchronicity between maternal and neonatal brains can be hypothesized. This study aimed to assess if neonatal and maternal cortical areas activated during breastfeeding are functionally synchronized since the second day of life. Materials and Methods: Twenty mothers and their term newborns were enrolled. Cortical activation during breastfeeding was identified by multichannel near-infrared spectroscopy, which detects changes in haemoglobin concentration from multiple cortical regions. Functional activity was simultaneously detected (hyperscanning) in mothers and newborns' frontal and motor/primary somatosensory cortical areas during the first 5 minutes of breastfeeding. Cluster analysis and Student's t test were used to detect oxygenated haemoglobin increase, as cortical activation estimate. Wavelet transform coherence (WTC) analysis was used to identify a possible synchronization between maternal and neonatal activated cortical regions. Results: Mothers showed an activation of the central motor/primary somatosensory cortex, above the sagittal fissure. In newborns, the bilateral frontal cortex was activated. WTC analysis revealed two different cyclical synchronizations between mothers and infants' activated cortical regions. Conclusions: Such evidence may reflect a very early common sharing of experiences, possibly associated with reciprocal dynamic motor adjustments, hormonal coregulation, and somatic stimulations and sensations. The observed cyclical neural synchronization, between the mother and her newborn's cortex during breastfeeding, may play an important role in promoting their bonding.","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141765428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rosalind Franklin Society Proudly Announces the 2023 Award Recipient for Breastfeeding Medicine. 罗莎琳德-富兰克林学会自豪地宣布 2023 年母乳喂养医学奖获得者。

IF 2.7 3区医学

Breastfeeding Medicine Pub Date : 2024-09-01 DOI: 10.1089/bfm.2024.93216.rfs2023

Debbie Noble-Carr

引用次数: 0