Breastfeeding Medicine最新文献

{"title":"Lactation Outcomes and Experiences Among Mothers of Infants with Congenital Heart Disease: A Scoping Review.","authors":"Larissa C Iapicca, Marina Magalhães, Angela Monk, Marion M Bendixen, Diane L Spatz, Leslie A Parker","doi":"10.1177/15568253251361928","DOIUrl":"10.1177/15568253251361928","url":null,"abstract":"<p><p><b><i>Background:</i></b> Infants with congenital heart disease (CHD) are at high risk for feeding difficulties and neurodevelopmental delays. Exclusive mother's own milk (MOM) reduces the risk of feeding intolerance and morbidity, yet feeding infants with CHD is complicated by decreased gastrointestinal perfusion, need for caloric fortification, and challenges in providing MOM by pump-dependent mothers. Lactation outcomes and support for pump-dependent mothers of infants with CHD are not well understood. <b><i>Methods:</i></b> We conducted a scoping review of original research identified in MEDLINE and Cumulative Index of Nursing and Allied Health Literature through November 2024 to identify key concepts, theories, and gaps in the literature on lactation support, outcomes, and experiences of mothers of infants with CHD. Studies were excluded if they were unavailable in English or were quality improvement projects, single case reports, or literature reviews. <b><i>Results:</i></b> Fourteen articles met the inclusion and exclusion criteria, of which 10 (71.4%) were quantitative. Results were grouped into five categories: (1) lactation outcomes, (2) lactation support, (3) lactation experiences, (4) barriers to breastfeeding and human milk (HM) feeding, and (5) predictors of breastfeeding and HM feeding. <b><i>Conclusions:</i></b> Mothers of infants with CHD can produce recommended MOM volumes by one month postpartum; however, breastfeeding and MOM feeding rates remain low in the first year. This review highlights barriers including inadequate support and mixed messaging from health care providers, emphasizing the need for further research, quality improvement measures, and health care provider education to address these challenges.</p>","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":"615-627"},"PeriodicalIF":1.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144854589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Storage Conditions on Mesenchymal Stem Cells in Breast Milk: A Randomized Study.","authors":"Ece Çetin, Deniz Genç, Sinem Gülcan Kersin, Elif Nisa Bahar, Ecem Öztop Gündoğdu, Muazzez Gökalp, Rabia Kahraman, Tunç Akkoç, Sabriye Senem Kılıç, Eren Özek","doi":"10.1089/bfm.2024.0370","DOIUrl":"10.1089/bfm.2024.0370","url":null,"abstract":"<p><p><b><i>Introduction:</i></b> Breast milk (BM) has numerous well-known, proven health benefits; however, the mechanisms underlying these effects are still not well-defined. Recent studies have shown that BM contains mesenchymal stem cells (MSCs), which might support both the growth and development of infants as well as provide protection from acute and chronic diseases. The effect of different conditions on the cellular components of BM is still unknown. This study focuses on investigating the influence of various storage methods on the properties of BM-derived MSCs. <b><i>Methods:</i></b> The study involved collecting 15 mL of BM samples from 17 participating mothers within the first week postpartum. MSC isolation was conducted on three sets of 5 mL samples from each participant: freshly obtained samples, refrigerated samples for 72 hours, and samples deep-frozen at -20°C for 1 month. Poststorage, MSCs were assessed for cell count, viability, and expression of specific markers using flow cytometry. <b><i>Results:</i></b> Analysis revealed a significant decrease in the average count of MSCs in BM poststorage. Freshly collected BM samples showed an average MSC count of 80.588,24 ± 50.0431,96, which significantly reduced to 28.333,33 ± 10.298,57 after 72 hours of refrigeration (<i>p</i> < 0.05). Despite this decrease, there was no notable change in the expression of MSC positive markers. Interestingly, MSCs were undetectable in samples stored in a deep freezer for one month upon microscopic examination. <b><i>Conclusion:</i></b> The study demonstrates a reduction in the viability of MSCs in BM when refrigerated, yet the surviving cells maintained their characteristic surface markers. However, freezing BM resulted in a complete loss of its MSC content.</p>","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":"672-680"},"PeriodicalIF":1.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144727973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Response to Letter:</i> Trahair, et al., <i>Breastfeeding Medicine</i> 30.5.2025.","authors":"Robin Jones","doi":"10.1177/15568253251359965","DOIUrl":"10.1177/15568253251359965","url":null,"abstract":"","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":"683"},"PeriodicalIF":1.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144625372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current Scope of Practice for Breastfeeding and Lactation Medicine Physicians and Providers: Description of an Emerging Subspecialty.","authors":"C B Rosen-Carole, E Prieto, F AlHreashy, F AlJaafar, M C Cornelio, C DeLeon, M T Hernandez-Aguilar, M J Paz, C Kariuki, Y LeFort, M Mansovsky, T Seo, R Strassman, N Tanaka, A Kellams","doi":"10.1089/bfm.2025.65870.abm","DOIUrl":"10.1089/bfm.2025.65870.abm","url":null,"abstract":"<p><p>Breastfeeding and Lactation Medicine is an emerging medical subspecialty that addresses the physiology, pathology, and sociodemographic components of breastfeeding and lactation. In the past 50 years, the field has grown into an international subspecialty supported by the Academy of Breastfeeding Medicine. Training programs are emerging in many countries, and it has become a reimbursable, board-certified medical specialty in the United States and Canada. Breastfeeding and Lactation Medicine providers manage routine and complex issues arising during lactation, across multiple care settings. Care requires a comprehensive skill set that includes a strong understanding of the distinct and interdependent physiologies of presenting patients as well as a consideration of the context in which families are immersed. Providers in this field are also advocates, researchers, policy consultants, and educators, leading global improvement in the clinical care and social support for families who are breastfeeding or lactating. Struggles for the field have included difficulties with institutionalizing programs, a research agenda not focused on diagnosis and management of common conditions, competition with commercial milk formula marketing practices, and limited training opportunities. This paper was developed by an international group of Breastfeeding and Lactation Medicine providers and the Academy of Breastfeeding Medicine to describe the scope of the field, who practices in the field, the problems addressed, challenges faced, and some cases that exemplify this work.</p>","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":"601-614"},"PeriodicalIF":1.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144834011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Lack of Benefit of Exposing the Premature Infant to Breast Milk Smell and/or Taste before Tube Feeding: A Double-Blind Randomized Clinical Trial.","authors":"Luana Geyse Ribeiro da Fonseca, Carla Adriane Leal, José Natal Figueiroa, João Guilherme Bezerra Alves","doi":"10.1089/bfm.2025.0042","DOIUrl":"10.1089/bfm.2025.0042","url":null,"abstract":"<p><p><b><i>Introduction:</i></b> Infants born very prematurely usually are initially feeding by orogastric or nasogastric tube. These infants lack the maternal milk smell and taste, both of which initiate the cephalic phase of nutrition. Offering the olfactory and gustatory experience of breast milk could enhance weight growth and expedite discharge, which are the primary advantageous outcomes for extremely premature infants. <b><i>Purpose:</i></b> To evaluate the potential of exposing very preterm newborns to the smell and taste of breast milk to expedite weight growth and facilitate early discharge. <b><i>Methods:</i></b> This study is a double-blind, randomized, superiority clinical trial. A study was conducted on infants born very prematurely (less than 32 weeks gestation) who were receiving tube feeding. Prior to tube feeding, the interventional group was exposed to the smell and taste of breast milk. The primary outcomes were an increase in weight and a shorter length of hospital stay. <b><i>Results:</i></b> A total of 63 children born very prematurely were randomly assigned and completed the research. The intervention and control groups did not exhibit any significant difference in terms of weight increase and time to discharge. The weight gain was 715 g (95% CI: 544 to 876 g) in the intervention group and 657 g (95% CI: 510 to 804 g) in the control group, with a <i>p</i> value of 0.60. The time to discharge was 39 days (95% CI: 30 to 48) in the intervention group and 37 days (95% CI: 28 to 54) in the control group, with a <i>p</i> value of 0.735. <b><i>Conclusion:</i></b> The smell and taste of breast milk right before tube feeding did not speed up weight growth or lead to early discharge in extremely premature newborns.</p>","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":"645-649"},"PeriodicalIF":1.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144265249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence, Concordance, and Risk Factors of Antibiotic Resistance Genes in Breast Milk and Neonatal Oral Cavity of Preterm Mother-Infant Pairs.","authors":"Sourabh Dutta, Ambika Sharma, Manisha Biswal, Anwesha Chakraborty, Vanita Suri, Pallab Ray","doi":"10.1089/bfm.2025.0092","DOIUrl":"10.1089/bfm.2025.0092","url":null,"abstract":"<p><p><b><i>Background:</i></b> Mothers delivering preterm are very often exposed to antibiotics in the peripartum period. We hypothesize this may select bacteria bearing antibiotic resistance genes (ARGs) in the breast milk and be transmitted to the neonate's mouth while feeding. This study aimed to determine the prevalence of ARGs coding for extended-spectrum beta-lactamases (ESBLs) (including AmpC beta-lactamases [ACBLs]) and carbapenemases in breast milk and neonatal oral swab samples of preterm mother-infant pairs, the concordance of ARGs between paired samples, and risk factors of ARGs coding for ESBLs and carbapenemases. <b><i>Methods:</i></b> Breast milk and oral swab samples were obtained aseptically from 100 preterm mother-infant pairs (gestation 28-34 weeks) by postpartum day 10. Multiplex PCR was used to detect 15 common ARGs in these samples. Potential risk factors of the presence of any ARG coding for ESBLs or carbapenemases in breast milk and oral swab samples were studied. <b><i>Results:</i></b> The commonest ARGs for ESBLs, ACBLs, and carbapenemases in breast milk were <i>bla_SHV</i> (28%), <i>bla_CIT</i> (33%), and <i>bla_IMP</i> (49%), respectively; and oral swabs <i>bla_CTX-M1</i> (30%), <i>bla_CIT</i> (58%), and <i>bla_IMP</i> (24%), respectively. ARGs common to breast milk and oral swabs included <i>bla_CIT</i> (13%), <i>bla_IMP</i> (10%), <i>bla_CTX-M-1</i> (9%), and <i>bla_SHV</i> (6%). Formula milk intake was associated with less oral carbapenemase ARGs. <b><i>Conclusion:</i></b> ARGs for ESBLs and carbapenemases are highly prevalent in preterm breast milk and oral swabs.</p>","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":"658-665"},"PeriodicalIF":1.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144504851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges in Breastfeeding Faced by the Lactating Gynecologic Surgeon.","authors":"Patricia GiglioAyers, Jessie Jones, Elizabeth A Hintz, Danielle Luciano, Amanda Ulrich","doi":"10.1177/15568253251371712","DOIUrl":"https://doi.org/10.1177/15568253251371712","url":null,"abstract":"<p><p><b><i>Objectives:</i></b> Characterize the experiences of lactating gynecologic surgeons, identify common challenges, and propose solutions to address barriers. <b><i>Methods:</i></b> In this mixed-methods, cross-sectional study, a novel survey was electronically distributed to measure lactation experiences among gynecologic surgeons. Descriptive statistics were used to analyze quantitative data, and thematic analysis was used for the qualitative data analysis. <b><i>Results:</i></b> Eighty-six survey respondents reported having been pregnant and met the eligibility criteria. The rate of breastfeeding was 95% (<i>n</i> = 82) among women who had given birth, and 91% (<i>n</i> = 75) of surgeons breastfed after returning to work. Of the 66 surgeons who shared lactation experiences, 97% (<i>n</i> = 64) reported challenges faced at work, and 86% (<i>n</i> = 57) faced more than one challenge. Most respondents were fellowship trained (85%, <i>n</i> = 56) and half delivered within the last 2 years (48%, <i>n</i> = 32). Analysis yielded eight themes and nine subthemes. The most common themes were time constraints (<i>n</i> = 48), difficulty balancing clinical responsibilities (<i>n</i> = 53), and pumping logistics (<i>n</i> = 59). Surgeons suffered from emotional distress (<i>n</i> = 14) and physical challenges included decreased supply, engorgement, and leakage (<i>n</i> = 16). <b><i>Conclusions:</i></b> Gynecologic surgeons face multiple challenges when lactating at work. This research highlights the lack of protection and support for the lactating surgeon. We propose solutions to address these workplace inequities, including allotted time for milk expression, adequate facilities, institutional and national policy and protections, and creation of a culture of support.</p>","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144942850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Doula Support and Breastfeeding Outcomes: A Systematic Review.","authors":"Anika Heuberger, Gabrielle Ramos, Wasana Weerasuriya, Noralbis Barrientos, Janelle Applequist, Adetola F Louis-Jacques","doi":"10.1177/15568253251367430","DOIUrl":"https://doi.org/10.1177/15568253251367430","url":null,"abstract":"<p><p><b><i>Introduction:</i></b> Breastfeeding is considered the ideal source of infant nutrition and has been shown to enhance maternal-infant health, but most women do not achieve their breastfeeding goals. Significant racial, ethnic, and socioeconomic disparities exist in breastfeeding outcomes. While current literature indicates a positive association between doula support and breastfeeding, the specific breastfeeding outcomes impacted by doulas remain unclear. Our objective was to synthesize existing literature on breastfeeding outcomes when doulas are utilized. <b><i>Methods:</i></b> Electronic searches were conducted in February 2022 and updated in April 2024 to include primary studies that examined doula support and breastfeeding outcomes (intention, initiation, duration, exclusivity, support, knowledge, education). Studies were excluded if they were secondary research or outside the perinatal period (pregnancy, childbirth, and/or up to 1 year postpartum). Data were extracted and synthesized narratively, and risk of bias was assessed. <b><i>Results:</i></b> A total of 1,917 deduplicated studies were screened, and 32 were included. Twenty-two studies were quantitative, and 10 studies were qualitative or mixed methods. Most studies (<i>n</i> = 24) consisted of birthing populations that experience marginalization, such as adolescents, low-income status, and racially/ethnically minoritized groups. Although doula support was associated with improved breastfeeding outcomes overall, there were mixed findings regarding breastfeeding duration and exclusivity. Lactating clients found doulas to be an important source of breastfeeding support, education, and knowledge. However, doulas reported a need for increased breastfeeding education during their training. Health care providers had limited knowledge of doulas' role in promoting breastfeeding. <b><i>Conclusion:</i></b> Doulas are associated with improved breastfeeding outcomes. Increased breastfeeding education in doula training and greater inclusion and awareness of doulas among the health care team could maximize this benefit.</p>","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144942799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Association of Mother and Infant Characteristics with the Macronutrient Content of Donor Human Milk.","authors":"Cuiping Liang, Hui Liang, Huimin Chen, Xiaoyu Guo, Hongfeng Luo, Minhua Xiao, Jing Sun","doi":"10.1177/15568253251371715","DOIUrl":"https://doi.org/10.1177/15568253251371715","url":null,"abstract":"<p><p><b><i>Background:</i></b> In southern China, little is known about the macronutrient content of donor human milk (DHM), which varies among donor mothers. <b><i>Research Aim:</i></b> This study aimed to evaluate the association of mother and infant characteristics with the macronutrient content of DHM. <b><i>Methods:</i></b> A retrospective analysis was conducted on the anthropometric data, age of delivery, and mode of delivery of 365 healthy donor mothers. In addition, the gender, birth weight, and age of the infants were also recorded. Finally, the relationship between these variables and the macronutrient content in DHM was analyzed. <b><i>Results:</i></b> When comparing DHM macronutrient content with age of delivery, mode of delivery, and birth weight, there was no statistical significance. DHM from the obese mother group contained a higher level of macronutrient content (fat, <i>p</i> = 0.025; dry matter, <i>p</i> = 0.020; energy, <i>p</i> = 0.002) than all other groups, including overweight, normal-weight, and low-weight groups. DHM from mothers in the early stage of lactation had a higher amount of total protein (<i>p</i> < 0.001) and true protein (<i>p</i> < 0.001). Statistically significant differences were observed for total protein (<i>p</i> = 0.034), true protein (<i>p</i> = 0.022), and dry matter (<i>p</i> = 0.011) when comparing infant's gender and DHM macronutrient content, with male infants showing higher values. <b><i>Conclusion:</i></b> This study indicated that the characteristics of mothers and infants may influence the macronutrient content of DHM. It is important to monitor factors that could affect the nutritional quality of DHM.</p>","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144942843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Randomized Control Trial of Early Breast Milk Pumping Interventions for Mothers of Moderately Preterm Infants.","authors":"Shuiqin Yuan, Hua Wang, Xinfen Xu, Qiufang Li","doi":"10.1177/15568253251365639","DOIUrl":"https://doi.org/10.1177/15568253251365639","url":null,"abstract":"<p><p><b><i>Objective:</i></b> To compare the effectiveness of different breast pumping interventions in breastfeeding for preterm mothers during the first 14 days postpartum. <b><i>Study Design:</i></b> In a single center, 69 preterm mothers were randomly allocated into three groups. Experimental Group 1 used a hospital-grade electric breast pump from postpartum days 1 to 14. Experimental Group 2 used a hospital-grade electric breast pump from postpartum days 1 to 5 and a personal standard bilateral electric breast pump from postpartum days 6 to 14. The control group used a personal standard bilateral electric breast pump from postpartum days 1 to 14. This study compared daily breast milk volume, time to lactogenesis II, and proportions of exclusive breast milk at 7 days, 3 months, and 6 months postdischarge. <b><i>Results:</i></b> The median daily milk volume was significantly higher in the experimental groups than in the control group from postpartum day 5 to day 14 (<i>p</i> < 0.05). Milk volume on postpartum days 5 and 14 showed a significant positive correlation (<i>r</i> = 0.74). The mean onset of lactogenesis II for all participants was 52.91 ± 17.30 hours, with significant differences among the groups (<i>p</i> = 0.018). Exclusive breast milk proportions were significantly higher in the experimental groups at 7 days and 3 months postdischarge (<i>p</i> < 0.05) but did not differ at 6 months (<i>p</i> = 0.143). <b><i>Conclusions:</i></b> Early use of a hospital-grade electric breast pump (within the first 5 days postpartum) promotes lactation in mothers of preterm infants, shortens the onset time of lactation, and improves exclusive breast milk proportions within 3 months postdischarge. These findings suggest that this approach is clinically beneficial and worth broader application.</p>","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144793487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}