Breastfeeding Medicine最新文献

{"title":"Early, Unplanned Lactation Cessation: Perspectives from a Breastfeeding Medicine Physician.","authors":"Anne R Eglash","doi":"10.1089/bfm.2025.0105","DOIUrl":"10.1089/bfm.2025.0105","url":null,"abstract":"","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":"528-529"},"PeriodicalIF":2.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144149512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Overview: Early, Unplanned Cessation of Lactation in Healthy and at-Risk Dyads: Priorities for Research and Practice.","authors":"Paula P Meier, Leslie A Parker","doi":"10.1089/bfm.2025.0115","DOIUrl":"https://doi.org/10.1089/bfm.2025.0115","url":null,"abstract":"","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":"20 7","pages":"458-459"},"PeriodicalIF":2.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pumping Behaviors, Pumped Milk Volume, and Maternal Opportunity Cost for Breast Pump-Dependent Mothers of Preterm Infants in the First 14 Postpartum Days.","authors":"Tricia J Johnson, Clarisa Medina-Poeliniz, Paula P Meier, Leslie A Parker, Rebecca Hoban","doi":"10.1089/bfm.2025.0057","DOIUrl":"https://doi.org/10.1089/bfm.2025.0057","url":null,"abstract":"<p><p><b><i>Objectives:</i></b> Describe pumping behaviors and pumped mother's own milk (MOM) volume by achievement of secretory activation (SA; MOM sodium [Na] concentration ≤16 mM), coming to volume (CTV; ≥500 mL pumped MOM/day), SA maintenance (continued daily Na ≤16 mM), and opportunity costs in the first 14 postpartum days for pump-dependent mothers of preterm infants in the neonatal intensive care unit. <b><i>Methods:</i></b> A secondary analysis of two prospective cohorts. Mothers recorded pumping and MOM volume for each pumping session during the first 14 postpartum days. Daily MOM Na concentration was measured to determine SA. The opportunity cost was the dollar value of time spent pumping. Regression models evaluated pumping behaviors, pumped MOM volume, and opportunity cost by SA and CTV achievement and SA maintenance. <b><i>Results:</i></b> Of 66 mothers, 94% and 41% achieved SA and CTV, respectively, and 44% of mothers who achieved SA maintained it through 14 days postpartum. Mothers who achieved SA had more pumping sessions (5.6 versus 4.3/day, <i>p</i> < 0.001), longer pumping duration (108 versus 83 minutes/day, <i>p</i> < 0.001), and higher pumped MOM volume (349 versus 218 mL/day, <i>p</i> < 0.001). Mothers who achieved versus did not achieve CTV pumped 5.6 versus 4.9 times/day (<i>p</i> = 0.050). Opportunity costs were $376 for mothers achieving SA, $155 higher than not achieving, and $441 for mothers maintaining SA, $94 higher than not maintaining SA. <b><i>Conclusion:</i></b> Pumped MOM volume and opportunity costs were higher for mothers who achieved and maintained SA. Strategies offsetting opportunity costs during the stressful early postpartum period for breast pump-dependent mothers of preterm infants are needed.</p>","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":"20 7","pages":"502-511"},"PeriodicalIF":2.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breastfeeding in the First Weeks Postpartum. Challenges and Realities.","authors":"Arthur I Eidelman","doi":"10.1089/bfm.2025.0123","DOIUrl":"10.1089/bfm.2025.0123","url":null,"abstract":"","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":"457"},"PeriodicalIF":2.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143961651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence, Concordance, and Risk Factors of Antibiotic Resistance Genes in Breast Milk and Neonatal Oral Cavity of Preterm Mother-Infant Pairs.","authors":"Sourabh Dutta, Ambika Sharma, Manisha Biswal, Anwesha Chakraborty, Vanita Suri, Pallab Ray","doi":"10.1089/bfm.2025.0092","DOIUrl":"https://doi.org/10.1089/bfm.2025.0092","url":null,"abstract":"<p><p><b><i>Background:</i></b> Mothers delivering preterm are very often exposed to antibiotics in the peripartum period. We hypothesize this may select bacteria bearing antibiotic resistance genes (ARGs) in the breast milk and be transmitted to the neonate's mouth while feeding. This study aimed to determine the prevalence of ARGs coding for extended-spectrum beta-lactamases (ESBLs) (including AmpC beta-lactamases [ACBLs]) and carbapenemases in breast milk and neonatal oral swab samples of preterm mother-infant pairs, the concordance of ARGs between paired samples, and risk factors of ARGs coding for ESBLs and carbapenemases. <b><i>Methods:</i></b> Breast milk and oral swab samples were obtained aseptically from 100 preterm mother-infant pairs (gestation 28-34 weeks) by postpartum day 10. Multiplex PCR was used to detect 15 common ARGs in these samples. Potential risk factors of the presence of any ARG coding for ESBLs or carbapenemases in breast milk and oral swab samples were studied. <b><i>Results:</i></b> The commonest ARGs for ESBLs, ACBLs, and carbapenemases in breast milk were <i>bla_SHV</i> (28%), <i>bla_CIT</i> (33%), and <i>bla_IMP</i> (49%), respectively; and oral swabs <i>bla_CTX-M1</i> (30%), <i>bla_CIT</i> (58%), and <i>bla_IMP</i> (24%), respectively. ARGs common to breast milk and oral swabs included <i>bla_CIT</i> (13%), <i>bla_IMP</i> (10%), <i>bla_CTX-M-1</i> (9%), and <i>bla_SHV</i> (6%). Formula milk intake was associated with less oral carbapenemase ARGs. <b><i>Conclusion:</i></b> ARGs for ESBLs and carbapenemases are highly prevalent in preterm breast milk and oral swabs.</p>","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144504851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Lack of Benefit of Exposing the Premature Infant to Breast Milk Smell and/or Taste before Tube Feeding: A Double-Blind Randomized Clinical Trial.","authors":"Luana Geyse Ribeiro da Fonseca, Carla Adriane Leal, José Natal Figueiroa, João Guilherme Bezerra Alves","doi":"10.1089/bfm.2025.0042","DOIUrl":"https://doi.org/10.1089/bfm.2025.0042","url":null,"abstract":"<p><p><b><i>Introduction:</i></b> Infants born very prematurely usually are initially feeding by orogastric or nasogastric tube. These infants lack the maternal milk smell and taste, both of which initiate the cephalic phase of nutrition. Offering the olfactory and gustatory experience of breast milk could enhance weight growth and expedite discharge, which are the primary advantageous outcomes for extremely premature infants. <b><i>Purpose:</i></b> To evaluate the potential of exposing very preterm newborns to the smell and taste of breast milk to expedite weight growth and facilitate early discharge. <b><i>Methods:</i></b> This study is a double-blind, randomized, superiority clinical trial. A study was conducted on infants born very prematurely (less than 32 weeks gestation) who were receiving tube feeding. Prior to tube feeding, the interventional group was exposed to the smell and taste of breast milk. The primary outcomes were an increase in weight and a shorter length of hospital stay. <b><i>Results:</i></b> A total of 63 children born very prematurely were randomly assigned and completed the research. The intervention and control groups did not exhibit any significant difference in terms of weight increase and time to discharge. The weight gain was 715 g (95% CI: 544 to 876 g) in the intervention group and 657 g (95% CI: 510 to 804 g) in the control group, with a <i>p</i> value of 0.60. The time to discharge was 39 days (95% CI: 30 to 48) in the intervention group and 37 days (95% CI: 28 to 54) in the control group, with a <i>p</i> value of 0.735. <b><i>Conclusion:</i></b> The smell and taste of breast milk right before tube feeding did not speed up weight growth or lead to early discharge in extremely premature newborns.</p>","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144265249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Viable Spore-Forming Obligate Anaerobes Are Rare in Pasteurized Donor Human Milk: A Pilot Study.","authors":"Tong Wu, Laura D Klein, Scott Markham, Richard Brown, Christine Sulfaro, Vanessa Clifford","doi":"10.1089/bfm.2025.0062","DOIUrl":"https://doi.org/10.1089/bfm.2025.0062","url":null,"abstract":"<p><p><b><i>Background:</i></b> When access to mother's own milk is limited, pasteurized donor human milk (PDHM) is the best alternative source of nutrition for high-risk preterm infants. Microbial screening of PDHM is essential to ensure its safety, as spore-forming bacteria may survive pasteurization. Standard screening will detect spore-forming bacteria that grow aerobically, such as <i>Bacillus cereus,</i> but may miss obligate anaerobes, such as <i>Clostridium</i> species. Although milk banking guidelines globally recommend microbial screening of milk batches, they do not specifically recommend anaerobic testing. This study aimed to determine the proportion of PDHM batches containing viable anaerobic bacteria after pasteurization. <b><i>Materials and Methods:</i></b> In this prospective cohort study, 150 batches of PDHM from unique donors were sampled (August-December 2024) at Australian Red Cross Lifeblood and tested at an accredited food safety laboratory. Prepasteurization samples were tested for aerobic bacteria, and postpasteurization samples were tested for both aerobic and anaerobic bacteria using a validated method (detection limit ≤1 CFU/mL). <b><i>Results:</i></b> No bacteria were recovered from any of the 150 postpasteurization samples tested using an anaerobic culture method. Using standard aerobic culture, 4.7% (7/150) of samples failed prepasteurization microbial screening according to local acceptance guidelines, due to a total colony count ≥ 10⁵ CFU/mL (<i>n</i> = 6) and/or the presence of Enterobacteriaceae ≥ 10⁴ CFU/mL (<i>n</i> = 3), and none failed postpasteurization testing. <b><i>Conclusions:</i></b> This study confirmed that obligate anaerobic bacteria are rarely cultured from PDHM. Additional process control through routine testing for anaerobes in PDHM is therefore not considered essential, particularly when PDHM is stored frozen (<18°C) after pasteurization. Clinicians should maintain vigilance for potential recipient adverse events and promptly report these to the source milk bank.</p>","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors that Are Associated with Increased Lactic Acid Bacteria Presence in Donated Human Milk.","authors":"Jurjana Novoselac, Katarina Butorac, Andreja Leboš Pavunc, Davor Ježek","doi":"10.1089/bfm.2025.0077","DOIUrl":"https://doi.org/10.1089/bfm.2025.0077","url":null,"abstract":"<p><p><b><i>Background:</i></b> Probiotic bacteria isolated from human milk can have a preventive effect against necrotizing enterocolitis and other risks of prematurity. The aim of the study is to identify the possible factors that can influence the presence of lactic acid bacteria (LAB) in donated human milk (DHM). <b><i>Methods:</i></b> Next-generation sequencing and selective microbiological culturing of samples from pools of raw DHM were performed. Data on the donors, their children, and the milk are correlated with the microbiological findings. A regression model is performed, to predict the probability of the presence of the genera <i>Lactobacillus</i> and <i>Bifidobacterium</i>. <b><i>Results:</i></b> The abundance of the genus <i>Bifidobacterium</i> positively correlated with the donor's body mass index (<i>p</i> = 0.050). The abundance of the <i>Lactobacillus</i> positively correlated with the lactation age (<i>p</i> = 0.007) and negatively with the total bacterial count on blood agar (<i>p</i> = 0.001). The abundance of the <i>Bifidobacterium</i> positively correlated with the growth on selective transgalactosylated oligosaccharides-propionate agar media (<i>p</i> = 0.036). In the regression model for predicting the probability of the presence of LAB, the feeding mode and the length of storage in the milk bank proved to be statistically significant predictors. <b><i>Conclusion:</i></b> The results of this study indicate that mature DHM, that has a lower bacterial count, that was stored in the milk bank for a shorter time after pool formation and that is donated from a mother exclusively breastfeeding her infant is assumed to have both LAB.</p>","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144233190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postpartum Breastfeeding Support: The Need to Be Available and Timely.","authors":"Jennifer A Ross","doi":"10.1089/bfm.2025.0120","DOIUrl":"https://doi.org/10.1089/bfm.2025.0120","url":null,"abstract":"","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144224257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of the COVID-19 Pandemic on the Association of Breastfeeding's Protective Effect on Postpartum Depression: A Comparative Analysis of Prepandemic and Pandemic Cohorts.","authors":"Amanda Vozzola, David E Vozzola, Dikea Roussos-Ross","doi":"10.1089/bfm.2024.0109","DOIUrl":"https://doi.org/10.1089/bfm.2024.0109","url":null,"abstract":"<p><p><b><i>Background:</i></b> Before the COVID-19 pandemic, research studies indicated that breastfeeding was protective against postpartum depression (PPD). This study aimed to evaluate the impact of the COVID-19 pandemic on the protective association between breastfeeding and PPD. <b><i>Methods:</i></b> We performed a retrospective cohort study by comparing the Edinburgh Postnatal Depression Scale (EPDS) scores for patients in two cohorts, pre-COVID-19 (April 2019 to February 2020) and COVID-19 (April 2020 to February 2021). A cross-sectional design using descriptive statistics, Pearson correlations, analysis of variance (ANOVA), and stepwise multiple regression analysis (MRA) analyzed the EPDS scores of a prepandemic cohort (<i>N</i> = 448) and a pandemic cohort (<i>N</i> = 468) of women seen at a tertiary academic medical center for their first postpartum visit. <b><i>Results:</i></b> In the prepandemic cohort, 77.3% of breastfeeding women exhibited an unlikely risk for PPD compared with 78.5% in the pandemic cohort. Pearson correlations showed that the breastfeeding group in both cohorts had significantly lower EPDS scores, was less likely to exhibit PPD, and had a lower risk of severe PPD. ANOVA showed that nonbreastfeeding women had significantly higher EPDS scores in both cohorts. Stepwise MRA showed that the EPDS item Q8 (\"I have felt sad or miserable\") was the most significant predictor of PPD in breastfeeding women (both cohorts) and nonbreastfeeding women (prepandemic cohort) but had escalated to Q9 (\"I have been so unhappy that I have been crying\") for nonbreastfeeding women in the pandemic cohort. <b><i>Conclusion:</i></b> In both the prepandemic and pandemic cohorts, breastfeeding women had significantly lower EPDS scores.</p>","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144198231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}