Luana Geyse Ribeiro da Fonseca, Carla Adriane Leal, José Natal Figueiroa, João Guilherme Bezerra Alves
{"title":"The Lack of Benefit of Exposing the Premature Infant to Breast Milk Smell and/or Taste before Tube Feeding: A Double-Blind Randomized Clinical Trial.","authors":"Luana Geyse Ribeiro da Fonseca, Carla Adriane Leal, José Natal Figueiroa, João Guilherme Bezerra Alves","doi":"10.1089/bfm.2025.0042","DOIUrl":"https://doi.org/10.1089/bfm.2025.0042","url":null,"abstract":"<p><p><b><i>Introduction:</i></b> Infants born very prematurely usually are initially feeding by orogastric or nasogastric tube. These infants lack the maternal milk smell and taste, both of which initiate the cephalic phase of nutrition. Offering the olfactory and gustatory experience of breast milk could enhance weight growth and expedite discharge, which are the primary advantageous outcomes for extremely premature infants. <b><i>Purpose:</i></b> To evaluate the potential of exposing very preterm newborns to the smell and taste of breast milk to expedite weight growth and facilitate early discharge. <b><i>Methods:</i></b> This study is a double-blind, randomized, superiority clinical trial. A study was conducted on infants born very prematurely (less than 32 weeks gestation) who were receiving tube feeding. Prior to tube feeding, the interventional group was exposed to the smell and taste of breast milk. The primary outcomes were an increase in weight and a shorter length of hospital stay. <b><i>Results:</i></b> A total of 63 children born very prematurely were randomly assigned and completed the research. The intervention and control groups did not exhibit any significant difference in terms of weight increase and time to discharge. The weight gain was 715 g (95% CI: 544 to 876 g) in the intervention group and 657 g (95% CI: 510 to 804 g) in the control group, with a <i>p</i> value of 0.60. The time to discharge was 39 days (95% CI: 30 to 48) in the intervention group and 37 days (95% CI: 28 to 54) in the control group, with a <i>p</i> value of 0.735. <b><i>Conclusion:</i></b> The smell and taste of breast milk right before tube feeding did not speed up weight growth or lead to early discharge in extremely premature newborns.</p>","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144265249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tong Wu, Laura D Klein, Scott Markham, Richard Brown, Christine Sulfaro, Vanessa Clifford
{"title":"Viable Spore-Forming Obligate Anaerobes Are Rare in Pasteurized Donor Human Milk: A Pilot Study.","authors":"Tong Wu, Laura D Klein, Scott Markham, Richard Brown, Christine Sulfaro, Vanessa Clifford","doi":"10.1089/bfm.2025.0062","DOIUrl":"https://doi.org/10.1089/bfm.2025.0062","url":null,"abstract":"<p><p><b><i>Background:</i></b> When access to mother's own milk is limited, pasteurized donor human milk (PDHM) is the best alternative source of nutrition for high-risk preterm infants. Microbial screening of PDHM is essential to ensure its safety, as spore-forming bacteria may survive pasteurization. Standard screening will detect spore-forming bacteria that grow aerobically, such as <i>Bacillus cereus,</i> but may miss obligate anaerobes, such as <i>Clostridium</i> species. Although milk banking guidelines globally recommend microbial screening of milk batches, they do not specifically recommend anaerobic testing. This study aimed to determine the proportion of PDHM batches containing viable anaerobic bacteria after pasteurization. <b><i>Materials and Methods:</i></b> In this prospective cohort study, 150 batches of PDHM from unique donors were sampled (August-December 2024) at Australian Red Cross Lifeblood and tested at an accredited food safety laboratory. Prepasteurization samples were tested for aerobic bacteria, and postpasteurization samples were tested for both aerobic and anaerobic bacteria using a validated method (detection limit ≤1 CFU/mL). <b><i>Results:</i></b> No bacteria were recovered from any of the 150 postpasteurization samples tested using an anaerobic culture method. Using standard aerobic culture, 4.7% (7/150) of samples failed prepasteurization microbial screening according to local acceptance guidelines, due to a total colony count ≥ 10<sup>5</sup> CFU/mL (<i>n</i> = 6) and/or the presence of Enterobacteriaceae ≥ 10<sup>4</sup> CFU/mL (<i>n</i> = 3), and none failed postpasteurization testing. <b><i>Conclusions:</i></b> This study confirmed that obligate anaerobic bacteria are rarely cultured from PDHM. Additional process control through routine testing for anaerobes in PDHM is therefore not considered essential, particularly when PDHM is stored frozen (<18°C) after pasteurization. Clinicians should maintain vigilance for potential recipient adverse events and promptly report these to the source milk bank.</p>","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jurjana Novoselac, Katarina Butorac, Andreja Leboš Pavunc, Davor Ježek
{"title":"Factors that Are Associated with Increased Lactic Acid Bacteria Presence in Donated Human Milk.","authors":"Jurjana Novoselac, Katarina Butorac, Andreja Leboš Pavunc, Davor Ježek","doi":"10.1089/bfm.2025.0077","DOIUrl":"https://doi.org/10.1089/bfm.2025.0077","url":null,"abstract":"<p><p><b><i>Background:</i></b> Probiotic bacteria isolated from human milk can have a preventive effect against necrotizing enterocolitis and other risks of prematurity. The aim of the study is to identify the possible factors that can influence the presence of lactic acid bacteria (LAB) in donated human milk (DHM). <b><i>Methods:</i></b> Next-generation sequencing and selective microbiological culturing of samples from pools of raw DHM were performed. Data on the donors, their children, and the milk are correlated with the microbiological findings. A regression model is performed, to predict the probability of the presence of the genera <i>Lactobacillus</i> and <i>Bifidobacterium</i>. <b><i>Results:</i></b> The abundance of the genus <i>Bifidobacterium</i> positively correlated with the donor's body mass index (<i>p</i> = 0.050). The abundance of the <i>Lactobacillus</i> positively correlated with the lactation age (<i>p</i> = 0.007) and negatively with the total bacterial count on blood agar (<i>p</i> = 0.001). The abundance of the <i>Bifidobacterium</i> positively correlated with the growth on selective transgalactosylated oligosaccharides-propionate agar media (<i>p</i> = 0.036). In the regression model for predicting the probability of the presence of LAB, the feeding mode and the length of storage in the milk bank proved to be statistically significant predictors. <b><i>Conclusion:</i></b> The results of this study indicate that mature DHM, that has a lower bacterial count, that was stored in the milk bank for a shorter time after pool formation and that is donated from a mother exclusively breastfeeding her infant is assumed to have both LAB.</p>","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144233190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Postpartum Breastfeeding Support: The Need to Be Available and Timely.","authors":"Jennifer A Ross","doi":"10.1089/bfm.2025.0120","DOIUrl":"https://doi.org/10.1089/bfm.2025.0120","url":null,"abstract":"","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144224257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amanda Vozzola, David E Vozzola, Dikea Roussos-Ross
{"title":"The Impact of the COVID-19 Pandemic on the Association of Breastfeeding's Protective Effect on Postpartum Depression: A Comparative Analysis of Prepandemic and Pandemic Cohorts.","authors":"Amanda Vozzola, David E Vozzola, Dikea Roussos-Ross","doi":"10.1089/bfm.2024.0109","DOIUrl":"https://doi.org/10.1089/bfm.2024.0109","url":null,"abstract":"<p><p><b><i>Background:</i></b> Before the COVID-19 pandemic, research studies indicated that breastfeeding was protective against postpartum depression (PPD). This study aimed to evaluate the impact of the COVID-19 pandemic on the protective association between breastfeeding and PPD. <b><i>Methods:</i></b> We performed a retrospective cohort study by comparing the Edinburgh Postnatal Depression Scale (EPDS) scores for patients in two cohorts, pre-COVID-19 (April 2019 to February 2020) and COVID-19 (April 2020 to February 2021). A cross-sectional design using descriptive statistics, Pearson correlations, analysis of variance (ANOVA), and stepwise multiple regression analysis (MRA) analyzed the EPDS scores of a prepandemic cohort (<i>N</i> = 448) and a pandemic cohort (<i>N</i> = 468) of women seen at a tertiary academic medical center for their first postpartum visit. <b><i>Results:</i></b> In the prepandemic cohort, 77.3% of breastfeeding women exhibited an unlikely risk for PPD compared with 78.5% in the pandemic cohort. Pearson correlations showed that the breastfeeding group in both cohorts had significantly lower EPDS scores, was less likely to exhibit PPD, and had a lower risk of severe PPD. ANOVA showed that nonbreastfeeding women had significantly higher EPDS scores in both cohorts. Stepwise MRA showed that the EPDS item Q8 (\"I have felt sad or miserable\") was the most significant predictor of PPD in breastfeeding women (both cohorts) and nonbreastfeeding women (prepandemic cohort) but had escalated to Q9 (\"I have been so unhappy that I have been crying\") for nonbreastfeeding women in the pandemic cohort. <b><i>Conclusion:</i></b> In both the prepandemic and pandemic cohorts, breastfeeding women had significantly lower EPDS scores.</p>","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144198231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Breastfeeding MedicinePub Date : 2025-06-01Epub Date: 2025-03-17DOI: 10.1089/bfm.2024.0372
Anita Noble, Mirna Khader Kasasfeh, Smadar Eventov Friedman, Lawrence M Noble
{"title":"Knowledge and Attitudes of Donor Human Milk of Mothers in the Palestinian Territories and Israel.","authors":"Anita Noble, Mirna Khader Kasasfeh, Smadar Eventov Friedman, Lawrence M Noble","doi":"10.1089/bfm.2024.0372","DOIUrl":"10.1089/bfm.2024.0372","url":null,"abstract":"<p><p><b><i>Introduction:</i></b> Donor human milk (DHM) is the next best option when mothers' milk is unavailable. The study objective was to examine mothers' knowledge and attitudes regarding DHM. <b><i>Materials and Methods:</i></b> A prospective, descriptive, online study using mixed methods. Regression analysis was used to control for confounding variables and content analysis for the qualitative component. <b><i>Results:</i></b> Eighty mothers from the Palestinian Territories and Israel participated. Mothers' mean objective knowledge score was 3.4/6, and self-evaluation knowledge score was 2.4/5, with religion significant for both scores (<i>p</i> < 0.001 and <i>p</i> = 0.002), respectively. Compared with Muslim mothers, Christian and Jewish mothers were more likely to prefer DHM to formula: (adjusted odds ratio [95% confidence interval], 4.9 [1.5-16.6], and 17.5 [4.3-71.4]), donate HM (human milk) to a friend or relative (7.8 [2.0-30.3]) and 60 [9.9-362.3]) or donate HM to a human milk bank (5.4 [1.3-23.3] and 11.2 [2.6-47.5]). Muslim and Christian mothers were more likely to state that DHM was permissible only under certain circumstances. Regression analysis revealed that only religion was significant for mothers' response that DHM was permissible (<i>p</i> < 0.001). Qualitative analysis revealed that differences in mothers' knowledge and attitudes were related to milk kinship. <b><i>Conclusions:</i></b> In this first study of mothers' knowledge and attitudes of DHM in the Palestinian Territories and Israel, results revealed low knowledge and negative attitudes regarding DHM correlated with the mother's culture. Future programs should include culturally competent initiatives regarding the benefits of DHM.</p>","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":"395-401"},"PeriodicalIF":2.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Breastfeeding MedicinePub Date : 2025-06-01Epub Date: 2025-03-21DOI: 10.1089/bfm.2024.0382
Şeyma Ertugral Mollaahmetoglu, Gulten Guvenc
{"title":"The Effect of Breast Massage and Warm Compress Application on Milk Production and Anxiety in Mothers with Premature Newborn: A Randomized Controlled Trial.","authors":"Şeyma Ertugral Mollaahmetoglu, Gulten Guvenc","doi":"10.1089/bfm.2024.0382","DOIUrl":"10.1089/bfm.2024.0382","url":null,"abstract":"<p><p><b><i>Objective:</i></b> The aim of this study is to examine the effects of breast massage and warm compression on milk secretion and anxiety in the mothers of premature newborns. <b><i>Methods:</i></b> In this randomized controlled trial, 120 mothers of premature newborns in the neonatal intensive care unit (NICU) were assigned to three intervention groups (massage, <i>n</i> = 30; warm compression, <i>n</i> = 30; massage-warm, <i>n</i> = 30) and one control group (<i>n</i> = 30). Mothers in the massage group performed massage, those in the warm compression group applied compresses, and the combined group used both methods, whereas the control group used a breast pump with no intervention. Milk production was measured in milliliters (mL) after each pumping session over 4 days, and anxiety levels were assessed at baseline and on the 4th day. <b><i>Results:</i></b> Mothers with premature newborns in the NICU had mean breast milk amounts of 1,321.43 ± 569.01 mL in the massage group, 1,470 ± 718.93 mL in the warm compression group, 1,484.23 ± 889.28 mL in the massage-warm group, and 913.75 ± 679.90 mL in the control group. The massage, warm compression, and massage-warm groups had significantly higher milk production than the control group (<i>p</i> < 0.05). In addition, anxiety levels in the intervention groups significantly decreased compared with the control group (<i>p</i> < 0.05). Mothers reported satisfaction with all interventions, with no significant differences between the groups (<i>p</i> > 0.05). <b><i>Conclusion:</i></b> Breast massage, warm compression, and breast massage-warm compression can be suggested as effective, simple, and cost-effective methods for increasing milk quantity and decreasing maternal anxiety.</p>","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":"416-423"},"PeriodicalIF":2.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143668634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Effect of Foot Reflexology on Postpartum Comfort and Breastfeeding Outcomes in Postpartum Women: A Meta-Analysis Study.","authors":"Dilek Menekse, Ahsen Demirhan Kayacik, Kevser Ilcioglu","doi":"10.1089/bfm.2024.0395","DOIUrl":"10.1089/bfm.2024.0395","url":null,"abstract":"<p><p><b><i>Introduction:</i></b> In recent years, foot reflexology has been frequently used as a method to solve problems such as stress, pain, and depression. It has been observed that the studies focused on the effect of foot reflexology on the pregnancy and birth process. <b><i>Research Aim:</i></b> A meta-analysis of experimental trials evaluating the effectiveness of foot reflexology applied in the postpartum period on comfort and breastfeeding outcomes was conducted in the present study. <b><i>Materials and Methods:</i></b> A comprehensive electronic search was done through the PubMed, WoS, Wiley, ScienceDirect, Scopus, and Google Scholar databases to identify experimental articles. There was no time restriction when searching the database. The risk of bias was assessed using the Joanna Briggs Institute (JBI) critical appraisal checklist for quasi-experimental studies and the Cochrane risk of bias tool for randomized trials. The meta-analysis was conducted using Comprehensive Meta-Analysis. Cochran's Q test and Higgins' <i>I</i><sup>2</sup> were used to assess study heterogeneity. <b><i>Results:</i></b> Three studies, two randomized controlled trials and one quasi-experimental trial (<i>n</i> = 260), were included in the analysis. Foot reflexology applied to postpartum women was found to have positive effects on the LATCH (standardized mean difference [SMD]: 1.010, confidence interval [CI]: 0.752/1.269, Z = 7.664, <i>p</i> = 0.000), Visual Analogue Scale (VAS)-breast tension (SMD: 2.212, CI: 1.902/2.522, Z = 13.981, <i>p</i> = 0.000), VAS-breast heat (SMD: 2.240, CI: 1.928/2.552, Z = 14.086, <i>p</i> = 0.000), VAS-breast pain (SMD: 2.302, CI: 1.836/2.768, Z = 9.686, <i>p</i> = 0.000), postpartum comfort (SMD: 3.578, CI: 3.131/4.025, Z = 15.689, <i>p</i> = 0.000), and breastfeeding satisfaction (SMD: 1.492, CI: 1.178/1.806, Z = 9.318, <i>p</i> = 0.000) scores. <b><i>Conclusions:</i></b> This meta-analysis determined that the foot reflexology intervention increased breastfeeding success, satisfaction, and postpartum comfort levels and statistically significantly reduced the signs of breastfeeding onset.</p>","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":"441-449"},"PeriodicalIF":2.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143975181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Breastfeeding MedicinePub Date : 2025-06-01Epub Date: 2025-03-19DOI: 10.1089/bfm.2024.0315
Laura Hahn, Eva-Maria Dreyer, Marilena Thomann, Susanne Beyer, Lucia Ehmann, Franziska Ganster, Magdalena Jegen, Sven Mahner, Thomas Kolben, Sarah Meister
{"title":"Satisfaction with Breastfeeding and Not Frequency of Feeding is Associated with a Reduction of Postpartum Depressive Symptoms.","authors":"Laura Hahn, Eva-Maria Dreyer, Marilena Thomann, Susanne Beyer, Lucia Ehmann, Franziska Ganster, Magdalena Jegen, Sven Mahner, Thomas Kolben, Sarah Meister","doi":"10.1089/bfm.2024.0315","DOIUrl":"10.1089/bfm.2024.0315","url":null,"abstract":"<p><p><b><i>Purpose:</i></b> Postpartum depression (PPD) resembles a major depression in the postpartum period and affects 10-15% of all women after giving birth. Several studies suggest an association between a lower risk of PPD and breastfeeding. The highly stressful period of the COVID-19 pandemic has led to an increase in the incidence of mental illness in general and PPD in particular. Our aim was to investigate the relationship between breastfeeding behavior and PPD in more detail. <b><i>Methods:</i></b> In this context, 291 women who gave birth between April 2020 and September 2021 were surveyed up to 6 months postpartum on depressive symptoms, breastfeeding behavior, and anxieties. <b><i>Results:</i></b> In particular, the fact that the women stated after 6 months that their expectations of breastfeeding had been met appeared to lead to a significantly lower risk of PPD. Therefore, not breastfeeding frequency but satisfaction with breastfeeding behavior was decisive for the risk of PPD development. Significant correlations were found between different anxieties and breastfeeding behavior. Higher anxieties led to a shorter desired time of breastfeeding in months, less frequent breastfeeding per day, and less satisfaction with breastfeeding behavior. <b><i>Conclusion:</i></b> Our results suggest that improving the breastfeeding experience as well as reducing prepartum anxieties or treating postpartum anxieties could be a primary prevention for PPD.</p>","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":"424-431"},"PeriodicalIF":2.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Breastfeeding MedicinePub Date : 2025-06-01Epub Date: 2025-03-13DOI: 10.1089/bfm.2024.0334
Leslie Strickler, Alex Baker, Hannah DeGonza, Razan Alkhouri
{"title":"Intussusception in an Infant Chronically Ingesting Marijuana Via Breastfeeding.","authors":"Leslie Strickler, Alex Baker, Hannah DeGonza, Razan Alkhouri","doi":"10.1089/bfm.2024.0334","DOIUrl":"10.1089/bfm.2024.0334","url":null,"abstract":"<p><p><i><b>Background:</b></i> Use of marijuana and its derivatives has become increasingly common, without clear knowledge of health impacts. This uncertainty includes breastfeeding mothers and infants who may chronically ingest marijuana. <i><b>Case Presentation:</b></i> We present an infant with altered mental status initially thought to be the result of acute symptomatic exposure to tetrahydrocannabinol (THC). The infant subsequently developed classical symptoms of intussusception. <i><b>Conclusion:</b></i> This case raises the question of chronic THC exposure/ingestion in infants as a risk factor for intussusception. This association has been reported in adult populations, but not to date, in pediatric patients.</p>","PeriodicalId":9142,"journal":{"name":"Breastfeeding Medicine","volume":" ","pages":"450-452"},"PeriodicalIF":2.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143622998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}