Brain injury最新文献_第3页

Ictal-interictal spectrum: an EEG warning sign of hypertensive encephalopathy. 初-间期频谱：高血压脑病的脑电图警告信号。

IF 1.5 4区医学

Brain injury Pub Date : 2025-04-18 DOI: 10.1080/02699052.2025.2493785

Pei-Hao Chen, Hsin-Hui Wang, Yi-Hsuan Tang, Chien-Hung Lin, Wei-Sheng Lin

{"title":"Ictal-interictal spectrum: an EEG warning sign of hypertensive encephalopathy.","authors":"Pei-Hao Chen, Hsin-Hui Wang, Yi-Hsuan Tang, Chien-Hung Lin, Wei-Sheng Lin","doi":"10.1080/02699052.2025.2493785","DOIUrl":"https://doi.org/10.1080/02699052.2025.2493785","url":null,"abstract":"Objective: Hypertensive encephalopathy may complicate the course of pediatric nephrotic syndrome, and the resulting brain injury is not always reversible. Subclinical electroencephalographic activities may play a role in this context, as demonstrated by the case vignette.Method: We report on a girl with IgA nephropathy and secondary hypertension, leading to posterior reversible encephalopathy syndrome (PRES). The correlated neuroimaging and electroencephalographic findings are examined, and their clinical implications are discussed.Results: PRES could be associated with lateralized periodic discharges on electroencephalogram, which was topographically concordant with neuroimaging findings in this patient. Despite being clinically silent, the lateralized periodic discharges may potentially increase cerebral metabolic demand and adversely impact the neurological outcomes.Conclusion: Electroencephalographic monitoring should be considered in the context of PRES, as it may help detect subclinical electrical activities in the brain, which is of potential therapeutic relevance.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"1-3"},"PeriodicalIF":1.5,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143963192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Post-cerebral ischemia energy crisis: the role of glucose metabolism in the energetic crisis. 脑缺血后能量危机：葡萄糖代谢在能量危机中的作用。

IF 1.5 4区医学

Brain injury Pub Date : 2025-04-16 DOI: 10.1080/02699052.2025.2492751

Jia-Ting Li, Dian Ou, Yi-Ming Shi, Le Bao, Yan-Ling Li, Ting-Ting Xiong, Yang Bai, Huang Ding

{"title":"Post-cerebral ischemia energy crisis: the role of glucose metabolism in the energetic crisis.","authors":"Jia-Ting Li, Dian Ou, Yi-Ming Shi, Le Bao, Yan-Ling Li, Ting-Ting Xiong, Yang Bai, Huang Ding","doi":"10.1080/02699052.2025.2492751","DOIUrl":"https://doi.org/10.1080/02699052.2025.2492751","url":null,"abstract":"Background: Cells universally employ an efficiency-driven metabolic switch mechanism during nutritional changes, growth, and differentiation, transitioning from oxidative phosphorylation (OXPHOS) to glycolysis to ensure survival under hypoxic conditions or high energy demands. In cerebral ischemia, inadequate blood supply causes oxygen and energy deprivation, prompting brain cells to initiate glycolytic reprogramming to meet urgent energy needs. While this adaptation is a temporary solution, it may lead to lactic acidosis, aggravated inflammation, and increased free radical production. Prolonged reperfusion with sustained glycolysis can exacerbate brain cell damage, potentially causing irreversible harm.Objectives: This review systematically examines the dynamic changes in glucose metabolic transport mechanisms and the roles of immediate, early, intermediate, and late responder cells, along with their regulatory factors, in glycolytic reprogramming.Methods: Using a temporal analysis framework based on the body's natural response sequence to pathological events, we elucidate how cells at different stages collaborate to address glucose metabolism reprogramming under pathological conditions.Conclusions: Reversing glucose metabolism reprogramming and inhibiting glycolysis may improve the pathological processes of ischemic stroke, offering potential therapeutic benefits.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"1-11"},"PeriodicalIF":1.5,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143957530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Feasibility and efficacy of a group intervention to develop social support and resilience in family members of individuals with TBI. 团体干预对TBI患者家庭成员社会支持和恢复力发展的可行性和有效性。

IF 1.5 4区医学

Brain injury Pub Date : 2025-04-14 DOI: 10.1080/02699052.2025.2491787

Robin A Hanks, Grahame Simpson, Brigid Waldron Perrine, Lisa J Rapport, Robert Kotasek, Scott Millis

{"title":"Feasibility and efficacy of a group intervention to develop social support and resilience in family members of individuals with TBI.","authors":"Robin A Hanks, Grahame Simpson, Brigid Waldron Perrine, Lisa J Rapport, Robert Kotasek, Scott Millis","doi":"10.1080/02699052.2025.2491787","DOIUrl":"https://doi.org/10.1080/02699052.2025.2491787","url":null,"abstract":"Objective: Evaluate the clinical utility of the Strength 2 Strength (S2S) program to compare the effectiveness of a 1-day intensive intervention to the 5-week intervention, with regard to improving resilience and social support in families and friends of persons with TBI.Methods: Thirty-three participants received the 1-day, 5-h intervention, and 32 participants received the 5-week, 2-h intervention. Eighteen participants were waitlist controls. Outcome measures included the Connor-Davidson Resilience Scale, Family Resilience Scale, Social Provision Scale, and a 6-item questionnaire to assess satisfaction with the intervention and self-care.Results: Feasibility and efficacy of the S2S intervention was demonstrated. It did not increase resilience, but it kept social support stable during the COVID-19 pandemic. The control group showed decreases in social support.Conclusions: Clinical utility of the program in friends and families of those with TBI was evident and prevented deterioration in social support. Participant satisfaction was supported by the small attrition rate. Similar effects were associated with the brief and longer versions of the intervention, indicating that this type of intervention was carried out in an efficient manner for those who are already struggling to juggle the many needs of being a care partner.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"1-8"},"PeriodicalIF":1.5,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143959629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Involvement of physiological reactivity and interoception in emotional experience after a traumatic brain injury. 创伤性脑损伤后情绪体验中生理反应和内感受的参与。

IF 1.5 4区医学

Brain injury Pub Date : 2025-04-13 DOI: 10.1080/02699052.2025.2490977

Alice Bodart, Sandra Invernizzi, Laurent Lefebvre, Mandy Rossignol

{"title":"Involvement of physiological reactivity and interoception in emotional experience after a traumatic brain injury.","authors":"Alice Bodart, Sandra Invernizzi, Laurent Lefebvre, Mandy Rossignol","doi":"10.1080/02699052.2025.2490977","DOIUrl":"https://doi.org/10.1080/02699052.2025.2490977","url":null,"abstract":"Objective: Emotional experience is based, among other factors, on physiological reactivity (PR) and the awareness of this reactivity corresponding to interoception. After a traumatic brain injury (TBI), patients exhibit reduced PR and interoception, raising questions about the integrity of their emotional experience.Method: To examine this issue, 26 men with moderate to severe TBI (age: 37 ± 11) and 26 healthy male controls (age: 35 ± 14) watched emotional films (amusement, tenderness, anger, disgust). PR was measured via electrodermal activity (EDA) and heart rate variability (HRV). After each film, an emotional evaluation was completed using the Differential Emotional Scale (DES). Interoception was measured through a heartbeat counting (HBC) task and the Multidimensional Assessment of Interoceptive Awareness (MAIA) questionnaire.Results: Compared to controls, TBI participants scored lower on the MAIA Emotional Awareness and Noticing subscales, and exhibited lower EDA and HRV during the anger and tenderness films. However, emotional evaluations and HBC task scores were similar between groups. Positive correlations were found between emotional evaluation and the MAIA scale.Conclusion: These results suggest a dissociation between emotional experience and PR after TBI and decreased interoceptive sensitivity. Since interoception links PR and emotional experience, exploring the impact of reduced interoception on this dissociation could improve our understanding of post-TBI emotional functioning.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"1-12"},"PeriodicalIF":1.5,"publicationDate":"2025-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143976725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Successful cognitive rehabilitation for acute right frontal aslant tract injury with impaired working memory and inattention using diffusion tensor tractography. 急性右额斜束损伤伴工作记忆和注意力不集中的成功认知康复。

IF 1.5 4区医学

Brain injury Pub Date : 2025-04-12 DOI: 10.1080/02699052.2025.2490974

Masaharu Sawaki, Kazuya Motomura, Hiroyasu Yamamoto, Koei Ito, Yuto Suzuki, Masahiko Yamamoto

{"title":"Successful cognitive rehabilitation for acute right frontal aslant tract injury with impaired working memory and inattention using diffusion tensor tractography.","authors":"Masaharu Sawaki, Kazuya Motomura, Hiroyasu Yamamoto, Koei Ito, Yuto Suzuki, Masahiko Yamamoto","doi":"10.1080/02699052.2025.2490974","DOIUrl":"https://doi.org/10.1080/02699052.2025.2490974","url":null,"abstract":"Background: Language impairments caused by left frontal aslant tract (FAT) damage have a good prognosis. However, the prognosis of cognitive dysfunction after right FAT injury is unknown. The present study describes successful cognitive rehabilitation for impaired working memory and inattention together with diffusion tensor tractography (DTT).Methods: A patient in his 40s with acute stroke underwent magnetic resonance imaging, computed tomography perfusion scans, DTT, and 11 neuropsychological tests for attention, frontal lobe, memory, visuospatial, intelligence, and cognitive functions. Three weeks of cognitive rehabilitation, including direct attention and metacognitive strategy training, and visual working memory tasks were performed. DTT and neuropsychological assessments were compared before and after rehabilitation.Results: Neuropsychological scores in the Trail Making Test, Clinical Assessment for Attention, and Frontal Assessment Battery increased with step-by-step rehabilitation, leading to early reinstatement as a system engineer. DTT revealed that the FAT posterior segment adjacent to the lesion increased its distal branching in the inferior frontal gyrus.Conclusion: In this case study, cognitive rehabilitation for three weeks restored impaired working memory and attention while enhancing right FAT integrity. Visualizing white matter using DTT in the acute phase provides essential insights for selecting appropriate training tasks to facilitate functional recovery from neuropsychological disturbances.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"1-7"},"PeriodicalIF":1.5,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143962130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

"There's a lot that's different, but it's still me": exploring podcast narratives of emotional adjustment after encephalitis. “有很多不同，但它仍然是我”：探索脑炎后情绪调整的播客叙述。

IF 1.5 4区医学

Brain injury Pub Date : 2025-04-09 DOI: 10.1080/02699052.2025.2487612

Emma O'Connor, Antigoni Kasinopoulou, Danny O'Donoghue, Jane Sekibo, Eeshvari Morey, Jack Versace, Nicholas Cummins, Thomas Pollak, Ava Easton, Sara Simblett

{"title":"\"There's a lot that's different, but it's still me\": exploring podcast narratives of emotional adjustment after encephalitis.","authors":"Emma O'Connor, Antigoni Kasinopoulou, Danny O'Donoghue, Jane Sekibo, Eeshvari Morey, Jack Versace, Nicholas Cummins, Thomas Pollak, Ava Easton, Sara Simblett","doi":"10.1080/02699052.2025.2487612","DOIUrl":"https://doi.org/10.1080/02699052.2025.2487612","url":null,"abstract":"Background: Encephalitis can lead to acquired brain injury (ABI) with neuropsychiatric consequences. Emotional adjustment is important for ensuring positive, long-term outcomes. The transdiagnostic cognitive behavioral therapy (T-CBT) model offers a way of understanding adjustment post-encephalitis but has not yet been tested. We qualitatively assessed whether the T-CBT model accurately captured recovery experiences post-encephalitis and whether experiences differed between infectious and autoimmune encephalitis.Methods: A directed content analysis was used to inductively code spoken experiences of encephalitis survivors (n = 15), as told through public podcasts, and apply a deductive coding framework built from the T-CBT model. A second inductive content analysis was used to explore the podcast interview questions.Results: The T-CBT model broadly captured the experiences of emotional adjustment post-encephalitis. Threat to self-identity and responses to these threats, amongst other contextual factors, were important. An additional major category emerged to capture the impact of encephalitis on close others. No discernible pattern was found between survivors of infectious (n = 6) and autoimmune (n = 6) encephalitis.Conclusions: The T-CBT model with additional systemic factors can help to understand emotional adjustment after encephalitis and provides a rationale for psychological therapy as a treatment during the recovery phase.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"1-14"},"PeriodicalIF":1.5,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143957514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of sleep symptomatology post-concussion on return to sport in collegiate athletes. 脑震荡后睡眠症状对大学生运动员重返运动的影响。

IF 1.5 4区医学

Brain injury Pub Date : 2025-04-09 DOI: 10.1080/02699052.2025.2487933

Allison D Peplowski, Andrea L Liebl

{"title":"Effects of sleep symptomatology post-concussion on return to sport in collegiate athletes.","authors":"Allison D Peplowski, Andrea L Liebl","doi":"10.1080/02699052.2025.2487933","DOIUrl":"https://doi.org/10.1080/02699052.2025.2487933","url":null,"abstract":"Objective: To describe the relationship between sleep-symptom severity and number of days to return to play following concussion in student-athletes.Design: Case series.Setting: A D1 NCAA university athletic department (institutional care).Participants: The study enrolled 84 varsity athletes who suffered a sport-related concussion at the university from 2015 to 2021.Independent variables: Prior concussion(s), total symptom burden, and sleep symptomatology (sleeping more, sleeping less, trouble falling asleep, drowsiness, and fatigue) scores as reported using Post-Concussion Symptom Scale from the Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT).Main outcome measure: The number of days an athlete took to return to play following concussion.Results: Individuals who reported trouble falling asleep, sleeping less, fatigue, and drowsiness took significantly longer to return to play following concussion than individuals who did not report such symptoms (F1,102 = 34.12, p < 0.0001).Conclusions: Sleep symptomatology present after concussion is predictive of days until return to sport. This study demonstrates the importance of sleep symptomatology post-concussion for athletes.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"1-6"},"PeriodicalIF":1.5,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143960923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

What traditional neuropsychological assessment got wrong about mild traumatic brain injury. IV: clinical applications and future directions. 传统的神经心理学评估在轻度创伤性脑损伤上是错误的。四：临床应用及未来发展方向。

IF 1.5 4区医学

Brain injury Pub Date : 2025-04-03 DOI: 10.1080/02699052.2025.2486462

Erin D Bigler, Steven Allder, Benjamin T Dunkley, Jeff Victoroff

{"title":"What traditional neuropsychological assessment got wrong about mild traumatic brain injury. IV: clinical applications and future directions.","authors":"Erin D Bigler, Steven Allder, Benjamin T Dunkley, Jeff Victoroff","doi":"10.1080/02699052.2025.2486462","DOIUrl":"https://doi.org/10.1080/02699052.2025.2486462","url":null,"abstract":"Primary objective: Part IV concludes this four-part review of 'What Traditional Neuropsychological Assessment Got Wrong About Mild Traumatic Brain Injury,' with a focus on clinical applications and future directions.Methods and procedures: These reviews have highlighted the limitations of traditional neuropsychological assessment methods, particularly in the evaluation of the patient with mild traumatic brain injury (mTBI), and especially within the context of all of the 21st Century advances in neuroimaging, quantification and network neuroscience.Main outcome and results: How advanced neuroimaging technology and contemporary network neuroscience can be applied to assessing the mTBI patient at this time along with neuroimaging of the future are reviewed. The current status of computerized neuropsychological test (CNT) development is reviewed as it applies to mTBI assessment. Likewise, how the future of various types of virtual reality (VR), artificial intelligence (AI), wearable sensors, and markerless gaming technology could enhance the mTBI CNT assessment tool box of the future is reviewed.Conclusions: The review concludes with some aspirational statements about how improvements along with novel CNT methods could be developed and integrated with advanced neuroimaging technologies in the future to be tailored to meet the needs of the mTBI patient.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"1-17"},"PeriodicalIF":1.5,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143779131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of a pneumonia risk score for post-acute rehabilitation in patients with severe acquired brain injury. 为严重后天性脑损伤患者的急性期后康复治疗制定肺炎风险评分。

IF 1.5 4区医学

Brain injury Pub Date : 2025-04-02 DOI: 10.1080/02699052.2025.2484754

Anne Louise Vandsø Svenningsen, Mohit Kothari, Simon Svanborg Kjeldsen, Jesper Fabricius

{"title":"Development of a pneumonia risk score for post-acute rehabilitation in patients with severe acquired brain injury.","authors":"Anne Louise Vandsø Svenningsen, Mohit Kothari, Simon Svanborg Kjeldsen, Jesper Fabricius","doi":"10.1080/02699052.2025.2484754","DOIUrl":"https://doi.org/10.1080/02699052.2025.2484754","url":null,"abstract":"Objective: To develop a pneumonia risk score for patients with severe acquired brain injury (sABI) hospitalized for post-acute rehabilitation.Methods: A prognostic model with data from 1,625 patients with sABI who were pneumonia-free at admission for rehabilitation. Candidate predictors were gathered within 72 hours following admission. Prognostic risk scores were calculated based on hazard ratios and combined in an overall pneumonia risk score ranging 0-10.Results: Predictors were age >50 years hazard ratio (HR) 1,83 (95% CI: 1.33; 2.53), male sex HR 2.43 (95% CI: 1.70; 3.46), diagnosis (stroke, traumatic or anoxic brain injury) HR 1.69 (95% CI: 1.12; 2.55), tube feeding HR 4.46 (95% CI: 2.59; 7.70), and functional independence measure score of 18 HR 2.06 (95% CI: 1.10; 3.85). A score of 8-10 encompassed those being at high-risk of pneumonia with a positive predictive value (PPV) of 35% (95% CI: 32-37), a score of 5-7 encompassed those being at medium risk with a PPV of 16% (95% CI: 14-17), and a score of 0-4 encompassed those being at low risk with a PPV of 4% (95%CI: 3-5).Conclusions: A prognostic score was developed to raise awareness of patients in post-acute rehabilitation who are at high risk of pneumonia. The prognostic score should be externally validated before being used outside the development setting.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"1-8"},"PeriodicalIF":1.5,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143762894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Loneliness in acquired brain injury; a qualitative exploration of lived experience. 后发性脑损伤中的孤独感对生活经验的定性探索。

IF 1.5 4区医学

Brain injury Pub Date : 2025-03-31 DOI: 10.1080/02699052.2025.2472190

Orla Duffy, Katy Pedlow, Jacqueline Pogue, Julie-Ann Jordan, Laura Dunlop, Rachael Agnew, Ian Taylor, Robert Rauch

{"title":"Loneliness in acquired brain injury; a qualitative exploration of lived experience.","authors":"Orla Duffy, Katy Pedlow, Jacqueline Pogue, Julie-Ann Jordan, Laura Dunlop, Rachael Agnew, Ian Taylor, Robert Rauch","doi":"10.1080/02699052.2025.2472190","DOIUrl":"https://doi.org/10.1080/02699052.2025.2472190","url":null,"abstract":"Objective: Loneliness is one of the biggest health concerns in the UK and is recognized as a health priority in Northern Ireland. Following an acquired brain injury (ABI), there is a sudden and catastrophic loss of function, impacting many areas of life, including loneliness. We explored the meaning of loneliness for adults with ABI and the experiences and factors influencing their loneliness.Design: Qualitative study including three focus groups and four individual interviews, using a semi-structured interview guide, and recorded online.Methods: Participants were recruited from the Community Brain Injury team caseload. Twenty-three adults (6 female, 17 male), ranging from 2 to 24 years post - ABI, participated. Data were thematically analyzed using a deductive approach, using framework analysis to guide theme development.Results: Loneliness had a different meaning to participants, yet all experienced it at some point in their journey post-ABI. Four themes were derived from the focus group transcriptions; 1) 'A black hole with no sun' (definition) 2) 'A missing piece' (impairments) 3) 'I've become poor old mum' (identity) 4) 'Our own kind' (coping). Sub-themes were derived providing an in-depth exploration.Conclusions: Supporting loneliness post-ABI is challenging and multifactorial. Early identification and support by clinical teams is crucial. The findings suggest mechanisms to provide such support, directly from those with lived experience.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"1-11"},"PeriodicalIF":1.5,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143751082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0