Brain injury最新文献_第10页

Evolution of dizziness-related disability in children following concussion: a group-based trajectory analysis. 儿童脑震荡后头晕相关残疾的演变：基于群体的轨迹分析。

IF 1.5 4区医学

Brain injury Pub Date : 2025-01-02 Epub Date: 2024-09-02 DOI: 10.1080/02699052.2024.2393635

Pierre Langevin, Kathryn J Schneider, Michal Katz-Leurer, Mathilde Chevignard, Lisa Grilli, Adrienne Crampton, Isabelle Gagnon

{"title":"Evolution of dizziness-related disability in children following concussion: a group-based trajectory analysis.","authors":"Pierre Langevin, Kathryn J Schneider, Michal Katz-Leurer, Mathilde Chevignard, Lisa Grilli, Adrienne Crampton, Isabelle Gagnon","doi":"10.1080/02699052.2024.2393635","DOIUrl":"10.1080/02699052.2024.2393635","url":null,"abstract":"Objective: This study aimed to identify Dizziness-Related Disability (DRD) recovery trajectories in pediatric concussion and assess clinical predictors of disability groups.Materials and methods: In this prospective cohort study, 81 children (8-17 years) diagnosed with an acute concussion took part in 3 evaluation sessions (baseline, 3-month, and 6-month). All sessions included the primary disability outcome, the Dizziness Handicap Inventory (DHI) to create the DRD recovery trajectories using group-based multi-trajectory modeling analysis. Each independent variable included general patients' characteristics, premorbid conditions, function and symptoms questionnaires, and clinical physical measures; and were compared between the trajectories with logistic regression models.Results: Low DRD (LD) trajectory (n = 64, 79%), and a High DRD (HD) trajectory (n = 17, 21%) were identified. The Predicting and Preventing Postconcussive Problems in Pediatrics (5P) total score (Odds Ratio (OR):1.50, 95% Confidence Interval (CI): 1.01-2.22), self-reported neck pain (OR:7.25, 95%CI: 1.24-42.36), and premorbid anxiety (OR:7.25, 95%CI: 1.24-42.36) were the strongest predictors of belonging to HD group.Conclusions: Neck pain, premorbid anxiety, and the 5P score should be considered initially in clinical practice as to predict DRD at 3 and 6-month. Further research is needed to refine predictions and enhance personalized treatment strategies for pediatric concussion.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"1-9"},"PeriodicalIF":1.5,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142104156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Follow-up visits after pediatric concussion and the factors associated with early follow-up: a population-based study in British Columbia. 小儿脑震荡后的随访以及与早期随访相关的因素：不列颠哥伦比亚省的一项人口研究。

IF 1.5 4区医学

Brain injury Pub Date : 2025-01-02 Epub Date: 2024-08-28 DOI: 10.1080/02699052.2024.2395382

Scott Ramsay, V Susan Dahinten, Manon Ranger, Shelina Babul, Elizabeth Saewyc

{"title":"Follow-up visits after pediatric concussion and the factors associated with early follow-up: a population-based study in British Columbia.","authors":"Scott Ramsay, V Susan Dahinten, Manon Ranger, Shelina Babul, Elizabeth Saewyc","doi":"10.1080/02699052.2024.2395382","DOIUrl":"10.1080/02699052.2024.2395382","url":null,"abstract":"Objectives: To explore the rates and timing of a first follow-up visit for children and adolescents with a concussive injury and to identify factors associated with follow-up timing.Methods: A descriptive, correlational design drawing on linked, population-based administrative data of concussed children and adolescents (ages 5-18 years) from the province of British Columbia (BC), Canada. Data were accessed through Population Data BC. Descriptive statistics and binary logistic regression were used to analyze the data.Results: From January 1, 2016 to December 31, 2017, we retrieved 22,601 cases of concussion, of which 19% had an early follow-up visit (N = 4,294), 4.9% had later follow-up (N = 1,107), and 76.1% had no follow-up (N = 17,200). The factors of older age, living in a rural area, higher socioeconomic status, and seeing a specialist physician at an initial concussion diagnosis were more likely to have an early follow-up visit.Conclusion: Early follow-up is important for recovery, but most children and adolescents with a concussion do not receive follow-up in BC.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"10-16"},"PeriodicalIF":1.5,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142079120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Concussion acutely disrupts auditory processing in division I football student-athletes. 脑震荡严重破坏了 I 组足球运动员的听觉处理能力。

IF 1.5 4区医学

Brain injury Pub Date : 2025-01-02 Epub Date: 2024-09-03 DOI: 10.1080/02699052.2024.2396012

Jennifer Krizman, Danielle Colegrove, Jenna Cunningham, Silvia Bonacina, Trent Nicol, Matt Nerrie, Nina Kraus

{"title":"Concussion acutely disrupts auditory processing in division I football student-athletes.","authors":"Jennifer Krizman, Danielle Colegrove, Jenna Cunningham, Silvia Bonacina, Trent Nicol, Matt Nerrie, Nina Kraus","doi":"10.1080/02699052.2024.2396012","DOIUrl":"10.1080/02699052.2024.2396012","url":null,"abstract":"Introduction: Diagnosis, assessment, and management of sports-related concussion require a multi-modal approach. Yet, currently, an objective assessment of auditory processing is not included. The auditory system is uniquely complex, relying on exquisite temporal precision to integrate signals across many synapses, connected by long axons. Given this complexity and precision, together with the fact that axons are highly susceptible to damage from mechanical force, we hypothesize that auditory processing is susceptible to concussive injury.Methods: We measured the frequency-following response (FFR), a scalp-recorded evoked potential that assesses processing of complex sound features, including pitch and phonetic identity. FFRs were obtained on male Division I Collegiate football players prior to contact practice to determine a pre-season baseline of auditory processing abilities, and again after sustaining a sports-related concussion. We predicted that concussion would decrease pitch and phonetic processing relative to the student-athlete's preseason baseline.Results: We found that pitch and phonetic encoding was smaller post-concussion. Student-athletes who sustained a second concussion showed similar declines after each injury.Conclusions: Auditory processing should be included in the multimodal assessment of sports-related concussion. Future studies that extend this work to other sports, other injuries (e.g. blast exposure), and to female athletes are needed.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"17-25"},"PeriodicalIF":1.5,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11668622/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142118976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Attrition, adherence, and compliance to exercise training interventions in persons with traumatic brain injury: a systematic review of training studies. 脑外伤患者运动训练干预的流失、坚持和依从性：训练研究的系统性回顾。

IF 1.5 4区医学

Brain injury Pub Date : 2025-01-02 Epub Date: 2024-09-24 DOI: 10.1080/02699052.2024.2403632

Carly L A Wender, Elijah Farrar, Brian M Sandroff

{"title":"Attrition, adherence, and compliance to exercise training interventions in persons with traumatic brain injury: a systematic review of training studies.","authors":"Carly L A Wender, Elijah Farrar, Brian M Sandroff","doi":"10.1080/02699052.2024.2403632","DOIUrl":"10.1080/02699052.2024.2403632","url":null,"abstract":"Background: Exercise training (ET) is a promising rehabilitation approach for long-term negative consequences of traumatic brain injury (TBI). However, little is known regarding overall rates of attrition, adherence, and compliance to ET in TBI.Objective: The purpose of this systematic review was to estimate average attrition, adherence, and compliance rates in ET studies in persons with TBI.Methods: Databases were searched from inception to April 15, 2024. Two authors independently extracted data related to attrition, adherence, compliance, and possible moderators identified a priori.Results: The average rate of attrition from 45 studies was 14.4%, although the majority of studies had small sample sizes (i.e. n < 42). Based on hierarchical linear regression, the most influential predictors of attrition were sample size and study design. A minority of studies reported adherence (44.4%) or compliance (22.2%) but those that did reported good average adherence (85.1%) and compliance (77.7%). These studies support the ability of persons with TBI to complete an ET intervention as prescribed.Conclusions: Researchers can use this information to ensure adequate power to detect a true effect of ET in persons with TBI. Researchers conducting ET studies in persons with TBI should clearly and thoroughly report data on attrition, adherence, and compliance.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"70-83"},"PeriodicalIF":1.5,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142341509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Approach to adult Moyamoya disease presenting as bilateral anterior circulation infarcts: a case report. 成人 Moyamoya 病表现为双侧前循环梗死的治疗方法：病例报告。

IF 1.5 4区医学

Brain injury Pub Date : 2024-12-05 Epub Date: 2024-07-27 DOI: 10.1080/02699052.2024.2385375

Atri Ghosh, Kunal Sareen, Phillip Thomas

{"title":"Approach to adult Moyamoya disease presenting as bilateral anterior circulation infarcts: a case report.","authors":"Atri Ghosh, Kunal Sareen, Phillip Thomas","doi":"10.1080/02699052.2024.2385375","DOIUrl":"10.1080/02699052.2024.2385375","url":null,"abstract":"Moyamoya disease (MMD) is a rare progressive condition of unknown etiology that affects the blood vessels in the brain and is characterized by narrowing or stenosis of the distal parts of the internal carotid and major intracranial arteries, leading to the development of fragile collateral supplies. This makes it a significant causative factor for both ischemic strokes as well as intracerebral hemorrhages. As per the recommendations by the Research Committee on Moyamoya disease in 2021, the diagnostic criteria for MMD are essentially based on indicative radiological findings on cerebral angiography or MRI Brain and MRA, after excluding possible differentials. In this case report, we present the case of a 45-year-old Asian lady who presented with sudden-onset headaches and right-sided weakness. Her admission non-contrast CT brain scan was undiagnostic. MRI brain and MRA scans revealed bilateral anterior circulation watershed infarcts of variable age along with supra-clinoid stenosis. She was initially treated with steroids for vasculitis after discussions with a multidisciplinary team involving neurologists, stroke physicians and neuro-radiologists; however, further imaging revealed a diagnosis of MMD, and she was subsequently referred for revascularization surgery. Given the limited number of similarly documented cases, we hope this report will contribute to the knowledge base.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"1250-1253"},"PeriodicalIF":1.5,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141787205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The correlation between the severity of paroxysmal sympathetic hyperactivity and plasma catecholamine levels in patients with severe traumatic brain injury. 严重脑外伤患者阵发性交感神经功能亢进的严重程度与血浆儿茶酚胺水平之间的相关性。

IF 1.5 4区医学

Brain injury Pub Date : 2024-12-05 Epub Date: 2024-07-27 DOI: 10.1080/02699052.2024.2380460

Sonia Bansal, Dhritiman Chakrabarti, Mathangi Krishnakumar, Sundaravadivel P, Dhaval Shukla, Gorantla Padmasri, Rita Christopher, T N Sathyaprabha

{"title":"The correlation between the severity of paroxysmal sympathetic hyperactivity and plasma catecholamine levels in patients with severe traumatic brain injury.","authors":"Sonia Bansal, Dhritiman Chakrabarti, Mathangi Krishnakumar, Sundaravadivel P, Dhaval Shukla, Gorantla Padmasri, Rita Christopher, T N Sathyaprabha","doi":"10.1080/02699052.2024.2380460","DOIUrl":"10.1080/02699052.2024.2380460","url":null,"abstract":"Background: There is limited literature investigating the catecholamine levels in patients with paroxysmal sympathetic hyperactivity (PSH) after traumatic brain injury (TBI). The primary objective of this study was to correlate the severity of PSH (assessed using the PSH-Assessment measure [AM]) with plasma catecholamine levels at a resting state.Methods: In this prospective case-control study, blood samples for epinephrine and norepinephrine estimation were obtained at rest on three consecutive days, only for 'cases' of PSH after severe TBI (s-TBI) and for control patients (matched for age, gender, and Glasgow coma scale [GCS].Results: Twenty-seven patients with PSH and 16 controls were recruited. The median PSH-AM score was 20 and 9 in cases and controls, respectively. The epinephrine and norepinephrine levels at rest did not correlate with the severity of PSH assessed during PSH paroxysms (p = 0.949 and 0.975). Norepinephrine levels increased in PSH patients over the 3 consecutive days, once PSH was diagnosed (p = 0.022). The length of hospital stay was longer and the motor-GCS score was lower in PSH patients, with no differences in other outcomes between the groups.Conclusion: Catecholamine levels in the inter-paroxysmal interval cannot be correlated with PSH severity assessed during the paroxysms. However, the results of the study need to be confirmed by a larger sample size as the study is underpowered.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"1212-1219"},"PeriodicalIF":1.5,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141787206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Leaving on a Jet Plane: reflections on working with a patient with complex acquired brain injury secondary to attempted suicide. 乘坐喷气式飞机离开：与一名继发于自杀未遂的复杂后天性脑损伤患者共事的反思。

IF 1.5 4区医学

Brain injury Pub Date : 2024-12-05 Epub Date: 2024-07-24 DOI: 10.1080/02699052.2024.2378847

Amanda Thorpe

{"title":"Leaving on a Jet Plane: reflections on working with a patient with complex acquired brain injury secondary to attempted suicide.","authors":"Amanda Thorpe","doi":"10.1080/02699052.2024.2378847","DOIUrl":"10.1080/02699052.2024.2378847","url":null,"abstract":"Objective: Despite indications that patients with Acquired Brain Injury (ABI) as a result of deliberate self-harm have more complex presentations and lower rehabilitation outcomes (Brenner, 2009)1, there is nominal published literature that considers adjustments to care for these individuals. A multifaceted and emotionally triggering subject, laced with clinical and ethical considerations, the lack of published articles may indicate the complexities surrounding this topic.Method: This case study reflects on the care of a young man on a specialist brain injury unit who had devastating physical and cognitive disabilities after a significant drug overdose. Because the patient was unable to make informed treatment choices, all medical care was delivered in the patient's best interest amidst questions and doubts about the value of continuing life-saving treatments and escalation plans.Results: This article is not to defend or challenge the decisions made during this patient's care, but reflects on the complexity and impact of these situations on the patient, the family, and the care team. The patient's father gave permission for this case review publication.Conclusion: Further investigation is needed to better understand the challenges faced by this population and to determine if bespoke pathways and therapy considerations are necessary to address these specific circumstances.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"1245-1249"},"PeriodicalIF":1.5,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141757100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A systematic literature review of the impact of impaired self-awareness on the process of rehabilitation in acquired brain injury. 关于自我意识受损对后天性脑损伤康复过程的影响的系统性文献综述。

IF 1.5 4区医学

Brain injury Pub Date : 2024-12-05 Epub Date: 2024-08-19 DOI: 10.1080/02699052.2024.2392161

Rebecca Di Somma, Peter Fleming

{"title":"A systematic literature review of the impact of impaired self-awareness on the process of rehabilitation in acquired brain injury.","authors":"Rebecca Di Somma, Peter Fleming","doi":"10.1080/02699052.2024.2392161","DOIUrl":"10.1080/02699052.2024.2392161","url":null,"abstract":"Background: Impaired self-awareness (ISA) is common in individuals with an acquired brain injury (ABI) and can lead to reduced awareness of one's difficulties. Previous reviews have found that ISA impacts on functional outcomes in rehabilitation. However, to date there has not been a systematic literature review which examines how ISA impacts on the process of rehabilitation in ABI populations.Method: A literature search was conducted using several databases in May 2024, including Academic Search Premier, CINAHL, MEDLINE, APA PsycARTICLES and APA PsycINFO. Seventeen articles were selected for the review and were analyzed using Narrative Synthesis.Results: Four themes arose from the findings, including goal setting, treatment adherence, engagement and willingness to change and time spent in hospital. ISA was found to impact on the value adult ABI participants placed in rehabilitation, which decreased treatment compliance, motivation, and engagement. ISA also impacted on goal setting and behavior and resulted in a longer length of time spent in hospital.Conclusion: This review emphasizes the impact of ISA on various aspects/processes of rehabilitation in ABI and provides considerations of how clinicians might adapt interventions to manage these difficulties.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"1185-1196"},"PeriodicalIF":1.5,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142003598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cluster-based analysis of PTSD-Checklist for DSM-5 (PCL-5) in civilians with post-concussive cognitive changes. 基于聚类分析的 PTSD-Checklist for DSM-5（PCL-5）在有震荡后认知变化的平民中的应用。

IF 1.5 4区医学

Brain injury Pub Date : 2024-12-05 Epub Date: 2024-07-31 DOI: 10.1080/02699052.2024.2381065

Erik A Fraunberger, Alison J Wilson, Adam Idriss, Christina Campbell, Regan King, Meng Wang, Chantel T Debert

{"title":"Cluster-based analysis of PTSD-Checklist for DSM-5 (PCL-5) in civilians with post-concussive cognitive changes.","authors":"Erik A Fraunberger, Alison J Wilson, Adam Idriss, Christina Campbell, Regan King, Meng Wang, Chantel T Debert","doi":"10.1080/02699052.2024.2381065","DOIUrl":"10.1080/02699052.2024.2381065","url":null,"abstract":"Objective: This study explores the relationship between PTSD symptoms and cognition in patients with persistent post-concussive symptoms (PPCS).Methods: Adults with PPCS presenting to a specialized brain injury clinic provided demographic and injury information and completed the PTSD checklist for DSM-5, Generalized Anxiety Disorder Scale-7 (GAD-7) and Patient Health Questionnaire-9 (PHQ-9). The Montreal Cognitive Assessment (MoCA) was used to screen for possible cognitive concerns. Multiple regression analysis (MLR) adjusting for age, sex, mechanism of injury, psychiatric history, number of previous concussions, months since most recent injury, and mental health questionnaire scores was used to determine associations between PTSD and cognition. Binomial logistic regression explored the relationship between domains of the MoCA and PCL-5 scores.Results: We found a negative correlation between MoCA scores, PCL-5 (ρ=-0.211, p = 0.009) and PHQ-9 (ρ=-0.187, p = 0.021) in patients with PPCS and collinearity of PCL-5 and PHQ-9 scores. Significantly higher Arousal and Reactivity cluster scores within the PCL-5 were associated with poorer scores on naming and abstract tasks on the MoCA.Conclusion: The association between specific PCL-5 clusters and lower MoCA scores may represent a viable target for psychotherapeutic and psychopharmacologic intervention in patients with cognitive changes associated with PPCS.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"1236-1244"},"PeriodicalIF":1.5,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141854752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluating performance of a near-infrared-spectroscopy-based and machine-learning-powered bio-optical sensitivity parameters in identifying intracranial hemorrhages in TBI across different age-groups. 评估基于近红外光谱和机器学习驱动的生物光学灵敏度参数在识别不同年龄组创伤性脑损伤颅内出血方面的性能。

IF 1.5 4区医学

Brain injury Pub Date : 2024-12-05 Epub Date: 2024-07-31 DOI: 10.1080/02699052.2024.2381056

Jaimin Shah, Shailendra Solanki, Abhishek Chandra, Mangukiya Laljibhai Shivabhai, Pooja Gwalani

{"title":"Evaluating performance of a near-infrared-spectroscopy-based and machine-learning-powered bio-optical sensitivity parameters in identifying intracranial hemorrhages in TBI across different age-groups.","authors":"Jaimin Shah, Shailendra Solanki, Abhishek Chandra, Mangukiya Laljibhai Shivabhai, Pooja Gwalani","doi":"10.1080/02699052.2024.2381056","DOIUrl":"10.1080/02699052.2024.2381056","url":null,"abstract":"Primary objective: To evaluate the accuracy of an innovative machine-learning-powered near-infrared spectroscopy (mNIRS)-based bio-optical sensitivity parameters, namely specific tissue optical index (STOI) and intracranial tissue optical index (ITOI) for effective triaging of patients with suspected traumatic brain injury (TBI) across different age-groups to facilitate timely intervention and curtail the silent epidemic.Research design: Prospective, observational, double-blinded, cross-sectional single-center.Methods: A total of 240 subjects suspected with TBI and recommended for head CT scan were enrolled. Findings of CT were compared with the bio-optical sensitivity parameters (STOI+ITOI) generated by the mNIRS system to detect intracranial hemorrhages (ICHs).Statistical software used: spss (ibm version 21.0) results: Bio-optical sensitivity parameters (STOI+ITOI) analysis of 1288 scanned lobes showed high specificity of 97% (CI 95-98%), sensitivity of 96% (CI 92-99%), and accuracy of 97% (CI 96-98%) across all ages, maintaining robust performance for detecting subdural, epidural, subarachnoid hemorrhages, and contusions. Also, the reliability in the diagnosis of ICH was evidenced by Youden's index of 0.93 and positive and negative likelihood ratios of 29.13 and 0.04, respectively.Conclusion: The mNIRS-based STOI+ITOI proves to be an effective triage tool for TBI, exhibiting superior diagnostic performance across all age-groups.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"1227-1235"},"PeriodicalIF":1.5,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141854753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0