Brain injury最新文献_第10页

Experiences and attitudes towards agitated behaviours in TBI ICU patients (EXSTATIC): understanding various management practices through qualitative interviews with nurses. 创伤性脑损伤ICU患者激动行为的经历和态度（EXSTATIC）：通过对护士的定性访谈了解各种管理做法。

IF 1.5 4区医学

Brain injury Pub Date : 2025-01-01 Epub Date: 2025-02-03 DOI: 10.1080/02699052.2025.2460022

Mar Saavedra-Mitjans, Pierre-Marie David, Caroline Arbour, Marc M Perreault, Maxime Roux, Anne Julie Frenette, Kosar Khwaja, Francis Bernard, David R Williamson

{"title":"Experiences and attitudes towards agitated behaviours in TBI ICU patients (EXSTATIC): understanding various management practices through qualitative interviews with nurses.","authors":"Mar Saavedra-Mitjans, Pierre-Marie David, Caroline Arbour, Marc M Perreault, Maxime Roux, Anne Julie Frenette, Kosar Khwaja, Francis Bernard, David R Williamson","doi":"10.1080/02699052.2025.2460022","DOIUrl":"10.1080/02699052.2025.2460022","url":null,"abstract":"Introduction & objectives: Agitation is a common complication after an acute TBI in ICU patients. Professionals have a range of strategies to address agitation. Yet the absence of evidence-based guidelines and how these strategies are implemented complicates the management and safety may often be compromised for both ICU professionals and patients. This project explores experiences and attitudes of ICU-nurses to better understand the management of agitated behaviors in acute TBI-patients.Methods: Semi-structured interviews were conducted with 12 ICU-nurses from two Level-1 trauma centers in Canada. The interviews explored experiences and perceptions of managing agitation in critically ill TBI-patients. Interviews were analyzed using thematic analysis, facilitating the examination of how management practices interface with contextual variables and clinical strategies.Results: Five themes were identified: (1) a variety of symptoms differing according to patient profile and time since awakening, (2) different agitation management approaches stem from different concerns, (3) strategies used by nurses to manage agitation, (4) contextual factors influence management, and (5) potential opportunities to improve integrated care model.Conclusions: This research describes nurses' perceptions and helps understand management of agitation, by considering underlying contexts and factors affecting TBI-agitated patients management, how ICU itself contributes to agitation and potential areas for improvement.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"598-609"},"PeriodicalIF":1.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

How can healthcare professionals work with families to address misaligned expectations of recovery in brain injury rehabilitation? A scoping review. 医疗保健专业人员如何与家庭合作，解决对脑损伤康复的不一致期望？范围审查。

IF 1.5 4区医学

Brain injury Pub Date : 2025-01-01 Epub Date: 2025-02-03 DOI: 10.1080/02699052.2025.2450603

Jessica Blake, Guy Peryer, Rachel Dance, Sheryl Parke, Aidin Aryankhesal, Morag Farquhar

{"title":"How can healthcare professionals work with families to address misaligned expectations of recovery in brain injury rehabilitation? A scoping review.","authors":"Jessica Blake, Guy Peryer, Rachel Dance, Sheryl Parke, Aidin Aryankhesal, Morag Farquhar","doi":"10.1080/02699052.2025.2450603","DOIUrl":"10.1080/02699052.2025.2450603","url":null,"abstract":"Introduction: Most survivors of severe acquired brain injuries will have significant long-term disability. During inpatient rehabilitation, families often have expectations of recovery that do not match healthcare professional opinion. This impacts on patient care, service processes, professional-family relations, and wellbeing. This review aimed to understand how family expectations are managed in this setting, and to explore potential areas of improvement.Method: A scoping review was conducted by searching CINAHL, Medline, EMBASE and Web of Science. Krieger et al's 'Conceptual Building Blocks' provided a framework to analyze the data using a 'best fit' framework synthesis approach.Results: Twenty-one papers were included in the review. Six sub-themes within three overarching themes were generated, which explored recommendations for effective expectation management. The sub-themes within the 'staff behaviors' theme were 'appropriate information provision,' 'open communication' and 'prioritize family.' Sub-themes within 'system behaviors' were 'cultural change' and 'increased resource.' 'Rehabilitation as a shared process' was the third theme.Discussion: Misaligned expectations of recovery appear to reflect a range of unmet family needs related to their position within the healthcare hierarchy, professional-family communication, and their involvement in rehabilitation processes. Early identification of family and healthcare professional expectations alongside regular review may prevent misunderstanding and conflict.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"551-564"},"PeriodicalIF":1.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143122297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Body mass index and sleep disorders after moderate-to-severe traumatic brain injury - a national TBI model systems study. 中重度创伤性脑损伤后的身体质量指数与睡眠障碍——一项全国性脑外伤模型系统研究。

IF 1.5 4区医学

Brain injury Pub Date : 2025-01-01 Epub Date: 2025-01-27 DOI: 10.1080/02699052.2025.2454422

Kan Ding, Amber Salter, Simon Driver, Flora M Hammond, Laura E Dreer, Risa Nakase-Richardson, Kathleen Bell

{"title":"Body mass index and sleep disorders after moderate-to-severe traumatic brain injury - a national TBI model systems study.","authors":"Kan Ding, Amber Salter, Simon Driver, Flora M Hammond, Laura E Dreer, Risa Nakase-Richardson, Kathleen Bell","doi":"10.1080/02699052.2025.2454422","DOIUrl":"10.1080/02699052.2025.2454422","url":null,"abstract":"Objective: To examine the relationship between body mass index (BMI), newly developed sleep disorders and functional outcome after moderate-to-severe traumatic brain injury (msTBI).Methods: Retrospective data from the TBI Model Systems National Database was analyzed, focusing on the independent association between BMI, sleep disorder diagnosis, and functional outcome as measured by the Extended Glasgow Outcome Scale (GOSE) at 1-year post-injury. Linear and logistic regression were used.Results: Out of 2,142 participants, 84% reported no sleep disorder (NSD), 9% reported a sleep disorder before TBI (PreSD), and 7% developed a sleep disorder after TBI (PostSD). Over 50% of participants were overweight or obese. After adjusting for demographic and clinical characteristics, a one-unit increase of BMI at the time of rehabilitation admission was associated with 3.7% higher odds of PostSD (OR [95%CI]: 1.037 [1.007, 1.068], p = 0.015). PostSD was associated with a 53.6% higher chance of unfavorable GOSE compared to NSD (OR [95%CI]: 1.536 [1.069-2.207], p = 0.02) and an 81.7% higher chance compared to PreSD (OR [95% CI]: 1.817 [1.137-2.905], p = 0.01).Conclusion: Being overweight/obese and developing a sleep disorder had adverse effects on functional outcome, emphasizing the importance of addressing sleep and lifestyle factors in post-msTBI rehabilitation.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"571-578"},"PeriodicalIF":1.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship between alcohol use and traumatic brain injury: evidence from Mendelian randomization. 酒精使用与创伤性脑损伤的关系：来自孟德尔随机化的证据

IF 1.5 4区医学

Brain injury Pub Date : 2025-01-01 Epub Date: 2025-02-02 DOI: 10.1080/02699052.2025.2460740

Xiaohang Zhang, Wenze Wu, Guisheng Zhou, Xi Huang, Min Xu, Qiulong Zhao, Hui Yan

{"title":"Relationship between alcohol use and traumatic brain injury: evidence from Mendelian randomization.","authors":"Xiaohang Zhang, Wenze Wu, Guisheng Zhou, Xi Huang, Min Xu, Qiulong Zhao, Hui Yan","doi":"10.1080/02699052.2025.2460740","DOIUrl":"10.1080/02699052.2025.2460740","url":null,"abstract":"Background: Observational studies suggest that alcohol consumption increases the risk of traumatic brain injury (TBI); however, the causality of this association remains unclear.Objectives: This study aimed to identify which drinking pattern is the primary factor influencing TBI.Method: Two-sample Mendelian randomization (MR) was used to assess whether drinking patterns (alcohol consumption, abuse, and intake frequency) are causally associated with TBI risk.Results: MR analysis revealed causal effects of alcohol intake frequency [odds ratio (OR) 0.806, 95% confidence interval (CI): 0.665-0.978, p = 0.028, beta: -0.215, se: 0.098], alcohol drinks per week (OR 1.772, 95% CI: 1.140-2.753, p = 0.011, beta: 0.572, se: 0.225), and alcohol abuse (OR 1.095, 95% CI: 1.006-1.192, p = 0.035, beta: 0.091, se: 0.043) on TBI. Additionally, no causal effect of alcohol consumption (OR 0.730, 95% CI: 0.264-2.025, p = 0.546, beta: -0.314, se: 0.520) or average monthly alcohol intake (OR 1.138, 95% CI: 0.805-1.609, p = 0.463, beta: 0.130, se: 0.177) on TBI was observed. Similarly, the effects of TBI on alcohol intake were statistically non-significant.Conclusion: Drinking patterns, including alcohol intake frequency and abuse, influence TBI, whereas TBI rarely influences drinking patterns.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"610-617"},"PeriodicalIF":1.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143077899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of sport-related concussion using objective eye tracking. 用客观眼动追踪评价运动相关脑震荡。

IF 1.5 4区医学

Brain injury Pub Date : 2025-01-01 Epub Date: 2025-02-18 DOI: 10.1080/02699052.2025.2465371

Anthony E Bishay, Kristen L Williams, Nick De Oliviera, Samuel W Fitch, Eunyoung Hong, Scott L Zuckerman, Douglas P Terry

{"title":"Evaluation of sport-related concussion using objective eye tracking.","authors":"Anthony E Bishay, Kristen L Williams, Nick De Oliviera, Samuel W Fitch, Eunyoung Hong, Scott L Zuckerman, Douglas P Terry","doi":"10.1080/02699052.2025.2465371","DOIUrl":"10.1080/02699052.2025.2465371","url":null,"abstract":"Objective: Evaluate EyeBOX in an adolescent sport-related concussion (SRC) population by comparing scores between concussed and non-concussed athletes, examining sensitivity/specificity, and assessing clinical recovery associations.Methods: A prospective, unmatched case-control study examined concussed adolescents (11-22 years) treated in a sports concussion clinic who underwent EyeBOX testing. Concussed participants completed symptom scales and follow-up assessments. Analyses included t-tests comparing groups, sensitivity/specificity analyses, and models examining relationships between BOX scores and recovery outcomes, including initial post-concussion symptom severity (PCSS) scores, return to learn (RTL), symptom resolution (SR), and return to play (RTP).Results: Participants included 36 youth athletes with SRCs and 30 non-concussed controls. BOX scores were significantly higher in concussed participants (7.9 ± 5.2) compared to controls (5.4 ± 5.1; t = 2.062, p = 0.043, Cohen's d = 0.479). Sensitivity for detecting concussion ranged from 22% (BOX>10) to 61% (BOX>5), while specificity ranged from 63%-87%. Multivariable linear regression showed that higher BOX scores predicted higher initial PCSS scores (β = 0.323, p = 0.049) but did not predict RTL, SR, or RTP.Conclusion: EyeBOX demonstrated moderate specificity but limited sensitivity for identifying SRC and scores were associated with initial symptom severity. While it may not be useful as a standalone diagnostic tool, EyeBOX may serve as an adjunct for confirming concussion in youth athletes.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"618-624"},"PeriodicalIF":1.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143448067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Approach to adult Moyamoya disease presenting as bilateral anterior circulation infarcts: a case report. 成人 Moyamoya 病表现为双侧前循环梗死的治疗方法：病例报告。

IF 1.5 4区医学

Brain injury Pub Date : 2024-12-05 Epub Date: 2024-07-27 DOI: 10.1080/02699052.2024.2385375

Atri Ghosh, Kunal Sareen, Phillip Thomas

{"title":"Approach to adult Moyamoya disease presenting as bilateral anterior circulation infarcts: a case report.","authors":"Atri Ghosh, Kunal Sareen, Phillip Thomas","doi":"10.1080/02699052.2024.2385375","DOIUrl":"10.1080/02699052.2024.2385375","url":null,"abstract":"Moyamoya disease (MMD) is a rare progressive condition of unknown etiology that affects the blood vessels in the brain and is characterized by narrowing or stenosis of the distal parts of the internal carotid and major intracranial arteries, leading to the development of fragile collateral supplies. This makes it a significant causative factor for both ischemic strokes as well as intracerebral hemorrhages. As per the recommendations by the Research Committee on Moyamoya disease in 2021, the diagnostic criteria for MMD are essentially based on indicative radiological findings on cerebral angiography or MRI Brain and MRA, after excluding possible differentials. In this case report, we present the case of a 45-year-old Asian lady who presented with sudden-onset headaches and right-sided weakness. Her admission non-contrast CT brain scan was undiagnostic. MRI brain and MRA scans revealed bilateral anterior circulation watershed infarcts of variable age along with supra-clinoid stenosis. She was initially treated with steroids for vasculitis after discussions with a multidisciplinary team involving neurologists, stroke physicians and neuro-radiologists; however, further imaging revealed a diagnosis of MMD, and she was subsequently referred for revascularization surgery. Given the limited number of similarly documented cases, we hope this report will contribute to the knowledge base.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"1250-1253"},"PeriodicalIF":1.5,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141787205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The correlation between the severity of paroxysmal sympathetic hyperactivity and plasma catecholamine levels in patients with severe traumatic brain injury. 严重脑外伤患者阵发性交感神经功能亢进的严重程度与血浆儿茶酚胺水平之间的相关性。

IF 1.5 4区医学

Brain injury Pub Date : 2024-12-05 Epub Date: 2024-07-27 DOI: 10.1080/02699052.2024.2380460

Sonia Bansal, Dhritiman Chakrabarti, Mathangi Krishnakumar, Sundaravadivel P, Dhaval Shukla, Gorantla Padmasri, Rita Christopher, T N Sathyaprabha

{"title":"The correlation between the severity of paroxysmal sympathetic hyperactivity and plasma catecholamine levels in patients with severe traumatic brain injury.","authors":"Sonia Bansal, Dhritiman Chakrabarti, Mathangi Krishnakumar, Sundaravadivel P, Dhaval Shukla, Gorantla Padmasri, Rita Christopher, T N Sathyaprabha","doi":"10.1080/02699052.2024.2380460","DOIUrl":"10.1080/02699052.2024.2380460","url":null,"abstract":"Background: There is limited literature investigating the catecholamine levels in patients with paroxysmal sympathetic hyperactivity (PSH) after traumatic brain injury (TBI). The primary objective of this study was to correlate the severity of PSH (assessed using the PSH-Assessment measure [AM]) with plasma catecholamine levels at a resting state.Methods: In this prospective case-control study, blood samples for epinephrine and norepinephrine estimation were obtained at rest on three consecutive days, only for 'cases' of PSH after severe TBI (s-TBI) and for control patients (matched for age, gender, and Glasgow coma scale [GCS].Results: Twenty-seven patients with PSH and 16 controls were recruited. The median PSH-AM score was 20 and 9 in cases and controls, respectively. The epinephrine and norepinephrine levels at rest did not correlate with the severity of PSH assessed during PSH paroxysms (p = 0.949 and 0.975). Norepinephrine levels increased in PSH patients over the 3 consecutive days, once PSH was diagnosed (p = 0.022). The length of hospital stay was longer and the motor-GCS score was lower in PSH patients, with no differences in other outcomes between the groups.Conclusion: Catecholamine levels in the inter-paroxysmal interval cannot be correlated with PSH severity assessed during the paroxysms. However, the results of the study need to be confirmed by a larger sample size as the study is underpowered.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"1212-1219"},"PeriodicalIF":1.5,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141787206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Leaving on a Jet Plane: reflections on working with a patient with complex acquired brain injury secondary to attempted suicide. 乘坐喷气式飞机离开：与一名继发于自杀未遂的复杂后天性脑损伤患者共事的反思。

IF 1.5 4区医学

Brain injury Pub Date : 2024-12-05 Epub Date: 2024-07-24 DOI: 10.1080/02699052.2024.2378847

Amanda Thorpe

{"title":"Leaving on a Jet Plane: reflections on working with a patient with complex acquired brain injury secondary to attempted suicide.","authors":"Amanda Thorpe","doi":"10.1080/02699052.2024.2378847","DOIUrl":"10.1080/02699052.2024.2378847","url":null,"abstract":"Objective: Despite indications that patients with Acquired Brain Injury (ABI) as a result of deliberate self-harm have more complex presentations and lower rehabilitation outcomes (Brenner, 2009)1, there is nominal published literature that considers adjustments to care for these individuals. A multifaceted and emotionally triggering subject, laced with clinical and ethical considerations, the lack of published articles may indicate the complexities surrounding this topic.Method: This case study reflects on the care of a young man on a specialist brain injury unit who had devastating physical and cognitive disabilities after a significant drug overdose. Because the patient was unable to make informed treatment choices, all medical care was delivered in the patient's best interest amidst questions and doubts about the value of continuing life-saving treatments and escalation plans.Results: This article is not to defend or challenge the decisions made during this patient's care, but reflects on the complexity and impact of these situations on the patient, the family, and the care team. The patient's father gave permission for this case review publication.Conclusion: Further investigation is needed to better understand the challenges faced by this population and to determine if bespoke pathways and therapy considerations are necessary to address these specific circumstances.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"1245-1249"},"PeriodicalIF":1.5,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141757100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A systematic literature review of the impact of impaired self-awareness on the process of rehabilitation in acquired brain injury. 关于自我意识受损对后天性脑损伤康复过程的影响的系统性文献综述。

IF 1.5 4区医学

Brain injury Pub Date : 2024-12-05 Epub Date: 2024-08-19 DOI: 10.1080/02699052.2024.2392161

Rebecca Di Somma, Peter Fleming

{"title":"A systematic literature review of the impact of impaired self-awareness on the process of rehabilitation in acquired brain injury.","authors":"Rebecca Di Somma, Peter Fleming","doi":"10.1080/02699052.2024.2392161","DOIUrl":"10.1080/02699052.2024.2392161","url":null,"abstract":"Background: Impaired self-awareness (ISA) is common in individuals with an acquired brain injury (ABI) and can lead to reduced awareness of one's difficulties. Previous reviews have found that ISA impacts on functional outcomes in rehabilitation. However, to date there has not been a systematic literature review which examines how ISA impacts on the process of rehabilitation in ABI populations.Method: A literature search was conducted using several databases in May 2024, including Academic Search Premier, CINAHL, MEDLINE, APA PsycARTICLES and APA PsycINFO. Seventeen articles were selected for the review and were analyzed using Narrative Synthesis.Results: Four themes arose from the findings, including goal setting, treatment adherence, engagement and willingness to change and time spent in hospital. ISA was found to impact on the value adult ABI participants placed in rehabilitation, which decreased treatment compliance, motivation, and engagement. ISA also impacted on goal setting and behavior and resulted in a longer length of time spent in hospital.Conclusion: This review emphasizes the impact of ISA on various aspects/processes of rehabilitation in ABI and provides considerations of how clinicians might adapt interventions to manage these difficulties.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"1185-1196"},"PeriodicalIF":1.5,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142003598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cluster-based analysis of PTSD-Checklist for DSM-5 (PCL-5) in civilians with post-concussive cognitive changes. 基于聚类分析的 PTSD-Checklist for DSM-5（PCL-5）在有震荡后认知变化的平民中的应用。

IF 1.5 4区医学

Brain injury Pub Date : 2024-12-05 Epub Date: 2024-07-31 DOI: 10.1080/02699052.2024.2381065

Erik A Fraunberger, Alison J Wilson, Adam Idriss, Christina Campbell, Regan King, Meng Wang, Chantel T Debert

{"title":"Cluster-based analysis of PTSD-Checklist for DSM-5 (PCL-5) in civilians with post-concussive cognitive changes.","authors":"Erik A Fraunberger, Alison J Wilson, Adam Idriss, Christina Campbell, Regan King, Meng Wang, Chantel T Debert","doi":"10.1080/02699052.2024.2381065","DOIUrl":"10.1080/02699052.2024.2381065","url":null,"abstract":"Objective: This study explores the relationship between PTSD symptoms and cognition in patients with persistent post-concussive symptoms (PPCS).Methods: Adults with PPCS presenting to a specialized brain injury clinic provided demographic and injury information and completed the PTSD checklist for DSM-5, Generalized Anxiety Disorder Scale-7 (GAD-7) and Patient Health Questionnaire-9 (PHQ-9). The Montreal Cognitive Assessment (MoCA) was used to screen for possible cognitive concerns. Multiple regression analysis (MLR) adjusting for age, sex, mechanism of injury, psychiatric history, number of previous concussions, months since most recent injury, and mental health questionnaire scores was used to determine associations between PTSD and cognition. Binomial logistic regression explored the relationship between domains of the MoCA and PCL-5 scores.Results: We found a negative correlation between MoCA scores, PCL-5 (ρ=-0.211, p = 0.009) and PHQ-9 (ρ=-0.187, p = 0.021) in patients with PPCS and collinearity of PCL-5 and PHQ-9 scores. Significantly higher Arousal and Reactivity cluster scores within the PCL-5 were associated with poorer scores on naming and abstract tasks on the MoCA.Conclusion: The association between specific PCL-5 clusters and lower MoCA scores may represent a viable target for psychotherapeutic and psychopharmacologic intervention in patients with cognitive changes associated with PPCS.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"1236-1244"},"PeriodicalIF":1.5,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141854752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0