Brain injury最新文献_第10页

Antiseizure medication possibly potentiates ictal bradycardia: a word of caution. 抗癫痫药物可能会加剧发作性心动过缓：需要警惕。

IF 1.5 4区医学

Brain injury Pub Date : 2025-02-23 Epub Date: 2024-11-08 DOI: 10.1080/02699052.2024.2424429

Namita Malhotra, Charu Mahajan, Ramesh Doddamani

引用次数: 0

Redefining adjustment after acquired brain injury. 重新定义后天性脑损伤后的适应。

IF 1.5 4区医学

Brain injury Pub Date : 2025-02-23 Epub Date: 2024-11-05 DOI: 10.1080/02699052.2024.2423760

S Buckland, E Kaminskiy, P Bright

{"title":"Redefining adjustment after acquired brain injury.","authors":"S Buckland, E Kaminskiy, P Bright","doi":"10.1080/02699052.2024.2423760","DOIUrl":"10.1080/02699052.2024.2423760","url":null,"abstract":"Background: Adjusting to life changes posed by an acquired brain injury (ABI) can be challenging for both individuals with ABI and their families. The current study explores the experience of adjustment, incorporating similarities and differences in this process as reported by the family members and individuals with ABI.Method: Thirty-nine participants, recruited from a regional brain injury charity group, took part in semi-structured interviews (20/39 individuals with ABI, 19/39 relatives). Transcripts were analyzed using thematic analysis.Findings: Three main categories of adjustment were developed: adjusted to life after ABI, partially adjusted to life after ABI and not adjusted to life after ABI. However, it is the complexity of experiences within these main categories which uncovers the diversity in individual experience. Of specific interest are adjustment as best case and resigned adjustment responses which indicate a level of burden for the person experiencing these feelings of adjustment.Conclusions: The categories of grateful acceptance and resigned acceptance were specific to relatives and show the need to look beyond the individual with ABI to identify where support may be required for a family as a whole. On the basis of these findings, we offer an inclusive, family-oriented conceptualization of adjustment to brain-injury.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"221-232"},"PeriodicalIF":1.5,"publicationDate":"2025-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142581603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Disparities in traumatic brain injury-related deaths-the United States, 2021. 创伤性脑损伤相关死亡的差异——美国，2021年。

IF 1.5 4区医学

Brain injury Pub Date : 2025-02-23 Epub Date: 2025-01-09 DOI: 10.1080/02699052.2024.2415933

Alexis Peterson, Karen Thomas, Scott Kegler

{"title":"Disparities in traumatic brain injury-related deaths-the United States, 2021.","authors":"Alexis Peterson, Karen Thomas, Scott Kegler","doi":"10.1080/02699052.2024.2415933","DOIUrl":"10.1080/02699052.2024.2415933","url":null,"abstract":"Objectives: This manuscript describes traumatic brain injury (TBI)-related mortality in the United States during 2021, by geography, sociodemographic characteristics, mechanism of injury, and injury intent.Method: Multivariable modeling of TBI mortality was performed to assess the simultaneous effect of multiple factors (geographic region, sex, race and ethnicity, and age) included in the model. Authors analyzed multiple-cause-of-death data from the National Vital Statistics System and included records when an International Classification of Diseases, Tenth Revision (ICD-10) underlying cause of death injury code, and a TBI-related ICD-10 diagnosis code were both listed.Results: During 2021, there were 69,473 TBI-related deaths. Rates were highest among older adults, males, and non-Hispanic American Indian/Alaska Native persons. A large proportion of all TBI-related deaths were attributed to unintentional falls and suicides. Model-based rates of TBI mortality revealed a divergent pattern with increasing rates by age group, while rate ratios simultaneously declined with age among specific racial/ethnic groups when compared with non-Hispanic White persons.Conclusion: Findings indicate unintentional falls and suicides remain a common cause of fatal TBI and specific groups are disproportionally affected by such injuries. Health care providers can play a role by assessing patients at increased risk for TBI and providing referrals for care and culturally tailored interventions when warranted.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"187-198"},"PeriodicalIF":1.5,"publicationDate":"2025-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142944421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of arousal recovery after cardiac arrest using diffusion kurtosis MRI with higher b-values: a pilot study. 使用较高 b 值的弥散峰度磁共振成像评估心脏骤停后的唤醒恢复情况：一项试点研究。

IF 1.5 4区医学

Brain injury Pub Date : 2025-02-23 Epub Date: 2024-11-05 DOI: 10.1080/02699052.2024.2424433

Matthew N Jaffa, Jiachen Zhuo, Jamie E Podell, Prashant Raghavan, Wan-Tsu W Chang, Melissa Motta, Nicholas A Morris, Neeraj Badjatia, Stephanie H Chen, Gunjan Y Parikh

{"title":"Assessment of arousal recovery after cardiac arrest using diffusion kurtosis MRI with higher b-values: a pilot study.","authors":"Matthew N Jaffa, Jiachen Zhuo, Jamie E Podell, Prashant Raghavan, Wan-Tsu W Chang, Melissa Motta, Nicholas A Morris, Neeraj Badjatia, Stephanie H Chen, Gunjan Y Parikh","doi":"10.1080/02699052.2024.2424433","DOIUrl":"10.1080/02699052.2024.2424433","url":null,"abstract":"Objective: Comatose survivors of cardiac arrest (CA) pose a complex challenge for physicians reliant on imperfect studies to determine the extent of neurologic injury. Clinically available imaging is frequently relied upon despite limited sensitivity. We conducted a prospective pilot study comparing diffusion kurtosis imaging (DKI)-MRI and somatosensory evoked potentials (SSEPs) in comatose survivors of CA to investigate the benefit of utilizing higher diffusion b-values to enhance prediction of arousal recovery.Methods: Survivors of CA admitted from June 2015 through November 2019 with DKI-MRI and SSEPs were evaluated. Advanced diffusion metrics differentiating present or absent SSEPs were analyzed using whole-brain voxelwise nonparametric permutation inference with threshold-free cluster enhancement.Results: Twenty survivors of CA were included, mean age 52, 45% female and out-of-hospital arrests accounting for 75% of cases. Baseline characteristics and examination findings were not statistically different between groups at admission or 48 h after achieving normothermia. A decrease in mean diffusivity (MD) and increase in mean kurtosis (MK) was demonstrated in subjects without arousal recovery potential, most prominently in the posterior mesial temporal, parietal and occipital lobes.Conclusion: DKI-MRI may improve early arousal recovery prediction during the immediate phase of post-CA care, especially where SSEPs are unavailable or unreliable.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"233-240"},"PeriodicalIF":1.5,"publicationDate":"2025-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142581602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Are standing balance and walking ability deficits poststroke related to the integrity of the corticospinal and non-corticospinal tracts? A meta-analysis. 中风后站立平衡和行走能力障碍与皮质脊髓束和非皮质脊髓束的完整性有关吗？一项荟萃分析。

IF 1.5 4区医学

Brain injury Pub Date : 2025-02-23 Epub Date: 2024-11-22 DOI: 10.1080/02699052.2024.2422382

Amber van Hinsberg, Renata Loureiro-Chaves, Jonas Schröder, Steven Truijen, Wim Saeys, Laetitia Yperzeele

{"title":"Are standing balance and walking ability deficits poststroke related to the integrity of the corticospinal and non-corticospinal tracts? A meta-analysis.","authors":"Amber van Hinsberg, Renata Loureiro-Chaves, Jonas Schröder, Steven Truijen, Wim Saeys, Laetitia Yperzeele","doi":"10.1080/02699052.2024.2422382","DOIUrl":"10.1080/02699052.2024.2422382","url":null,"abstract":"Background: The importance of corticospinal tract (CST) integrity in upper limb recovery poststroke is well established, but its association with standing balance and walking remains unclear. This meta-analysis aimed to establish the relationship between CST and non-CST motor tract integrity, and clinical scores of standing balance and walking poststroke.Methods: In July 2024, five databases were searched for studies, focusing on diffusion MRI metrics and clinical scores of standing balance and/or walking independence poststroke. Meta-analyses were conducted to pool correlation coefficients (r) and group differences (d) based on CST integrity.Results: Twenty-two studies were included. Cross-sectional analysis showed no correlation (r < .25) between CST metrics and the functional ambulation category (FAC) in the sub-acute phase. Weak prognostic associations were found for CST-FA and CST-FN with FAC. Significant FAC score differences were found between preserved- and disrupted CST groups in the sub-acute (d = .79) and chronic (d = 1.07) phase and for prognostic analysis (d = 1.40). Non-CST metrics showed no cross-sectional associations and mixed prognostic associations.Conclusions: CST integrity was not significantly associated with standing balance or walking independence in the sub-acute phase. Early CST integrity showed weak prognostic value for walking at 6 months. Multimodal longitudinal research is needed to improve lower limb recovery prognostics.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"163-178"},"PeriodicalIF":1.5,"publicationDate":"2025-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142685918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Time-to-surgery for traumatic brain injury in the hyperacute period: a systemic review and meta-analysis. 超急性期脑外伤的手术时间：系统回顾和荟萃分析。

IF 1.5 4区医学

Brain injury Pub Date : 2025-02-23 Epub Date: 2024-11-08 DOI: 10.1080/02699052.2024.2425735

Lijian Zhang, Hongfang Zhao, Luxuan Wang, Yanfang Shi, Chunhui Li

{"title":"Time-to-surgery for traumatic brain injury in the hyperacute period: a systemic review and meta-analysis.","authors":"Lijian Zhang, Hongfang Zhao, Luxuan Wang, Yanfang Shi, Chunhui Li","doi":"10.1080/02699052.2024.2425735","DOIUrl":"10.1080/02699052.2024.2425735","url":null,"abstract":"Objective: To study the functional outcomes of traumatic brain injury (TBI) patients who have undergone surgical intervention in the hyperacute phase (<24 h).Data sources: Cochrane Library, PubMed, Embase, Medline and Web of Science databases.Review methods: A meta-analysis of 7 trials involving 237 patients was performed. Patients were categorized into two groups based on time to surgery: within 6 h and within 24 h. Patients were also categorized into developed and developing regions. Effect estimates were calculated using a fixed-effects model and heterogeneity was assessed with Cochrane I² statistic.Results: Our findings revealed that those who underwent neurosurgery in the hyperacute phase of TBI were at risk of adverse outcomes. The odds ratio (OR) was 1.50 (95% CI 1.03-2.19). Subgroup analysis demonstrated that TBI patients who underwent surgery within 6 h were at a greater risk of adverse effects (OR, 1.72; 95% CI, 1.08-2.74). Moreover, a greater risk was observed in developing regions (OR, 2.33; 95% CI, 0.97-5.58).Conclusion: Earlier neurosurgical intervention in the acute phase of TBI might result in higher incidence of adverse events. Surgery would be postponed for TBI patients whose initial GCS score is greater than 8 during the hyperacute period.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"179-186"},"PeriodicalIF":1.5,"publicationDate":"2025-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142603082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment of intractable paradoxical herniation by invasive mechanical ventilation with increased positive end-expiratory pressure: a case report. 通过增加呼气末正压的有创机械通气治疗顽固性矛盾性疝气：病例报告。

IF 1.5 4区医学

Brain injury Pub Date : 2025-02-23 Epub Date: 2024-11-01 DOI: 10.1080/02699052.2024.2419379

Shanwen Chen

{"title":"Treatment of intractable paradoxical herniation by invasive mechanical ventilation with increased positive end-expiratory pressure: a case report.","authors":"Shanwen Chen","doi":"10.1080/02699052.2024.2419379","DOIUrl":"10.1080/02699052.2024.2419379","url":null,"abstract":"Objective: Paradoxical herniation (PH) is a rare but potentially life-threatening complication after decompressive craniectomy. The core treatment strategy for PH focuses on increasing intracranial pressure. Here, we present the treatment course of intractable PH in a 59-year-old patient with a traumatic acute subdural hematoma.Methods: The patient underwent two operations to evacuate intracranial hematomas followed by decompressive craniectomy within 48 h. Intractable PH was induced by persistent cerebrospinal fluid leakage due to multiple lumbar punctures. The condition was managed with conventional interventions, such as a supine position, intravenous fluid infusion, and multiple intrathecal saline injections, which have been proven to be inefficient. Owing to his unconsciousness and concurrent severe pneumonia, the patient underwent invasive mechanical ventilation with increased positive end-expiratory pressure (PEEP) to optimize oxygen delivery. PEEP was set at 10 cmH2O with the intention of facilitating alveolar recruitment.Results: Increased PEEP unexpectedly played a role in elevating intracranial pressure and, as a result, led to the complete resolution of PH. The patient gradually recovered and resumed his daily activities.Conclusions: Applying invasive mechanical ventilation with increased PEEP for treating intractable PH can yield a favorable outcome. It represents a novel approach to dealing with such a rare complication.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"241-246"},"PeriodicalIF":1.5,"publicationDate":"2025-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142557108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Functional network disruptions in youth with concussion using the Adolescent Brain Cognitive Development study. 利用青少年大脑认知发展研究发现脑震荡青少年的功能网络紊乱。

IF 1.5 4区医学

Brain injury Pub Date : 2025-02-23 Epub Date: 2024-10-16 DOI: 10.1080/02699052.2024.2416545

Elena Sheldrake, Eman Nishat, Anne L Wheeler, Benjamin I Goldstein, Nick Reed, Shannon E Scratch

{"title":"Functional network disruptions in youth with concussion using the Adolescent Brain Cognitive Development study.","authors":"Elena Sheldrake, Eman Nishat, Anne L Wheeler, Benjamin I Goldstein, Nick Reed, Shannon E Scratch","doi":"10.1080/02699052.2024.2416545","DOIUrl":"10.1080/02699052.2024.2416545","url":null,"abstract":"Objective: This study aimed to compare psychosocial outcomes and functional neuroimaging among youth with concussion, youth with anxiety, and age- and sex-matched controls.Methods: Using archival data from the Adolescent Brain Cognitive DevelopmentSM Study, we analyzed between-group differences in psychosocial outcomes measured by the Child Behavior Checklist's internalizing and externalizing problem scales, and assessed brain function using resting-state fMRI network-region connectivity (specifically frontoparietal network (FPN) and default mode network (DMN) connectivity with the amygdala).Results: Significant differences in psychosocial outcomes were found across all groups, with the anxiety group reporting the most internalizing problems, followed by the concussion group which significantly differed from controls. Additionally, FPN-amygdala connectivity was significantly reduced in the concussion group only; this reduced connectivity did not predict psychosocial outcomes across groups.Conclusion: This study provided preliminary findings that brain connectivity is reduced exclusively in individuals with concussion. Although disruptions were observed in the concussion group, further investigation is warranted to understand how disruptions may be associated with concussion symptoms. Studies that utilize well-defined control and study groups, and comprehensive cognitive and mental health measures will offer a deeper understanding of the relationship between brain function and psychosocial outcomes.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"199-210"},"PeriodicalIF":1.5,"publicationDate":"2025-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142457854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

LIMBIC military and tactical athlete research study: making lemonade 101. LIMBIC 军事和战术运动员研究：制作柠檬水 101。

IF 1.5 4区医学

Brain injury Pub Date : 2025-01-28 Epub Date: 2024-08-23 DOI: 10.1080/02699052.2024.2392251

Jacob E Resch, David X Cifu

{"title":"LIMBIC military and tactical athlete research study: making lemonade 101.","authors":"Jacob E Resch, David X Cifu","doi":"10.1080/02699052.2024.2392251","DOIUrl":"10.1080/02699052.2024.2392251","url":null,"abstract":"The Long-term Impact of Military-relevant Brain Injury Consortium-Military and Tactical Athlete Research Study (LIMBIC MATARS) program established in 2020 is comprised of 22 universities and health systems across the United States. The LIMBIC MATARS Consortium's goal is to increase understanding of the complexities of concussion in collegiate athletes by leveraging extant retrospective and novel prospective data sets through the application of innovative research designs. The manuscripts in this special issue represent findings from clinical data sets based on consensus-derived common data elements collected from the 2015-2016 to 2019-2020 sport seasons that include 1311 cases of collegiate athletes diagnosed with concussion. Using these data, LIMBIC MATARS investigators addressed hypotheses that included (1) factors, including access to athletic trainers, biological sex, and ADHD, that may influence recovery from concussion, (2) predisposing risks associated with reinjury after return-to-sport, such as sport type, and (3) therapeutic targets for intervention including language barriers, physical activity, return-to-learn, and sleep. This commentary introduces the methodology and 10 descriptive studies highlighting initial findings from the Consortium.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"85-87"},"PeriodicalIF":1.5,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142035207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Understanding of head injury assessment and return to play processes and associated factors in United States Major League Rugby players. 了解美国橄榄球大联盟球员头部受伤评估和重返赛场过程及相关因素。

IF 1.5 4区医学

Brain injury Pub Date : 2025-01-28 Epub Date: 2024-10-02 DOI: 10.1080/02699052.2024.2408563

Owen M Sheehy, Katherine J Hunzinger, Christine M Baugh, Julie M Stamm

{"title":"Understanding of head injury assessment and return to play processes and associated factors in United States Major League Rugby players.","authors":"Owen M Sheehy, Katherine J Hunzinger, Christine M Baugh, Julie M Stamm","doi":"10.1080/02699052.2024.2408563","DOIUrl":"10.1080/02699052.2024.2408563","url":null,"abstract":"Objectives: Evaluate professional rugby players' self-reported perceived understanding of the head injury assessment (HIA) and return to play (RTP) processes and determine factors related to understanding and trust pertaining to these processes.Methods: An electronic survey measured concepts of interest. A thematic analysis of player understanding was performed, and player statements were coded.Results: 207 U.S. Major League Rugby (MLR) players participated (26.7 ± 3.4 years). HIA and RTP protocol understanding was not correlated with concussion history (p = 0.41). International rugby experience and trust regarding MLR support of the following protocols and opposing team medical staff practices varied in their relationship to HIA understanding. Trust that all MLR teams follow the same protocols was positively correlated with all HIA questions (ps < 0.03). No HIA questions were correlated with trust in their own team's medical staff. All trust questions were significantly correlated with RTP process understanding. Qualitative analysis identified four HIA- and RTP-related themes: education needs, staffing needs, HIA criticisms, and importance of player safety.Conclusion: International playing experience and greater trust in the MLR and league stakeholders were associated with greater player understanding of the HIA and RTP protocols. These results provide insight into the importance of educating players on league-specific concussion protocols.","PeriodicalId":9082,"journal":{"name":"Brain injury","volume":" ","pages":"99-107"},"PeriodicalIF":1.5,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142364338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0