BMC Oral Health最新文献

{"title":"Adoption of minimally invasive dentistry in Palestine: assessing practices and barriers - a cross-sectional study.","authors":"Naji Arandi, Tarek Rabi","doi":"10.1186/s12903-025-07042-7","DOIUrl":"10.1186/s12903-025-07042-7","url":null,"abstract":"<p><strong>Aims: </strong>This study explored the diagnostic and treatment practices of Palestinian general dentists related to minimally invasive dentistry (MID) and identified perceived barriers to its broader application.</p><p><strong>Materials and methods: </strong>A cross-sectional online survey collected data from general dentists on demographics, MID-related practices, and barriers. Descriptive and inferential statistics were used to evaluate current practices and their associations with dentist demographics and professional characteristics.</p><p><strong>Results: </strong>A substantial proportion of dentists applied MID-related principles. Preventive, nonoperative approaches are slightly more common for occlusal lesions and more clearly favored for approximal lesions. Approximately two-thirds adopted conservative cavity designs such as vertical slots or saucer-shaped preparations, whereas approximately half preferred selective removal for deep caries. Most dentists opted to repair rather than replace defective restorations. Clinical experience had a stronger influence on these practices than gender or workplace setting did, and the main barriers included limited training, restricted access to modern materials and technologies, and low patient awareness.</p><p><strong>Conclusion: </strong>Palestinian dentists demonstrated variability in the application of MID-related practices, with greater use reported among more experienced practitioners and those in private practice. Addressing educational, infrastructural and cultural barriers could support broader integration of evidence-based, minimally invasive approaches into routine care. These findings set the foundation for developing national policies, curricular reform, and continuing education, underscoring their importance in advancing evidence-based, minimally invasive care in Palestine.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"1624"},"PeriodicalIF":3.1,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12522853/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145290750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing resin bonding to saliva-contaminated polyetheretherketone: comparative efficacy of cleaning methods.","authors":"Zhi-Cen Lu, Meng-Hui Yang, Wei-Yi Zhong, Ya-Xin Zheng, Guang Hong, Hao Yu","doi":"10.1186/s12903-025-06968-2","DOIUrl":"10.1186/s12903-025-06968-2","url":null,"abstract":"","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"1608"},"PeriodicalIF":3.1,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12522674/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145290938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of proanthocyanidins application on push-out bond strength of root canal filling after different final irrigation procedures.","authors":"Funda Fundaoğlu Küçükekenci, Ahmet Serkan Küçükekenci","doi":"10.1186/s12903-025-06905-3","DOIUrl":"10.1186/s12903-025-06905-3","url":null,"abstract":"<p><strong>Background: </strong>This study aims to investigate the effects of using EDTA, phytic acid (IP6), chitosan, and proanthocyanidin (PAs) as final irrigation solutions on the push-out bond strength (PBS) of root canal filling.</p><p><strong>Materials methods: </strong>In the present study, 56 extracted human incisors were utilized. All teeth were decoronated at the cementoenamel junction. Following the root canal chemomechanical preparation, the teeth were randomly divided into 7 groups according to the final irrigation procedures: Group 1: Control, Group 2: EDTA, Group 3: IP6, Group 4: Chitosan, Group 5: EDTA + PAs, Group 6: IP6 + PAs, Group 7: Chitosan + PAs. The root canals were filled using the cold lateral condensation technique with gutta-percha and resin-based root canal sealer. Samples were obtained horizontally cut from the apical third of the teeth and subjected to push-out bond strength (PBS) using a universal testing machine. Data was statistically analyzed using one-way ANOVA and post hoc Tukey HSD test (α = 0.05).</p><p><strong>Results: </strong>The highest value was obtained in Group 6 (12.14 ± 0.47 MPa), and the lowest value in Group 1 (5.80 ± 0,44 MPa) (P < 0.05). Group 6 has shown a higher PBS value than Group 5 (11.72 ± 0.14 MPa) and Group 7 (11.94 ± 0.42 MPa) (P > 0.05). There were statistically significant differences between all other groups, except Groups 3 and 4 (P < 0.05). The failure type was mostly adhesive, and no cohesive failures were observed.</p><p><strong>Conclusion: </strong>The use of EDTA, IP6, and chitosan for final irrigation has enhanced the bond strength values of resin-based root canal sealer to dentin. Furthermore, the use of PAs after EDTA, IP6, and chitosan increased the bond strength values more than when these solutions were used alone.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"1621"},"PeriodicalIF":3.1,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12522412/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145290731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between dental anomalies and skeletal malocclusions in different facial patterns in a Saudi subpopulation.","authors":"Abdulrahman K Alshammari, Muteb A Algharbi, Freah L Alshammary, Nabeel S Almotairy, Hatem D Alshammari, Maha M Rashdi, Sukinah H Alrahin, Fatimah H Alsalem, Ahmed A Madfa","doi":"10.1186/s12903-025-06979-z","DOIUrl":"10.1186/s12903-025-06979-z","url":null,"abstract":"","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"1616"},"PeriodicalIF":3.1,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12522675/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145290792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protective and therapeutic effects of hexagonal boron nitride against hydrogen peroxide-induced oxidative damage in human gingival fibroblasts.","authors":"Isil Yalcin Bilke, Bilge Meraci Yildiran, Akif Hakan Kurt, Cansu Kara Oztabag, Nese Aysit, Yapıncak Goncu, Mehmet Ali Sungur","doi":"10.1186/s12903-025-07010-1","DOIUrl":"10.1186/s12903-025-07010-1","url":null,"abstract":"<p><strong>Background: </strong>Oxidative stress plays a significant role in the progression of periodontal diseases. Hexagonal boron nitride (hBN) nanoparticles have antimicrobial, antiplaque, and antioxidant properties. The aim of this study to evaluate the protective and therapeutic effects of hBN against oxidative stress induced by hydrogen peroxide (H₂O₂) in human gingival fibroblast (HGF) cells.</p><p><strong>Methods: </strong>In this study, a primary cell line of HGFs was used. Oxidative stress was induced by treating the cells with 800 µM H₂O₂. hBN was applied at concentrations of 0.001, 0.005, and 0.01 mg/mL, either 2 h prior to or 2 h following H₂O₂ exposure. Cells were incubated for 24 h post-treatment. Cell viability was assessed using the 2,3-bis-[2-methoxy-4-nitro-5-sulfophenyl]-2 H-tetrazolium-5-carboxyanilide salt (XTT) assay. Additionally, the total oxidant status (TOS) was measured before and after oxidative damage at the 0.01 mg/mL hBN concentration.</p><p><strong>Results: </strong>hBN did not negatively affect cell viability in HGF cells at any concentration. The application of hBN to HGF cells before and after oxidative damage resulted in statistically significant (P < 0.001), albeit modest improvements in cell viability (2-5.5% and 3-6.5%, respectively). No significant differences were observed in TOS (P = 0.234), indicating that the cytoprotective effects were not mediated via alterations in TOS.</p><p><strong>Conclusions: </strong>Within the limitations of this in vitro study, hBN was found to enhance cell viability under H₂O₂-induced oxidative stress in HGF cells. These findings suggest a potential role for hBN in modulating antioxidant responses and supporting periodontal healing processes. However, their clinical relevance remains uncertain. Therefore, further mechanistic studies and clinical investigations are required to validate the potential adjunctive role of hBN in the prevention and treatment of periodontal diseases.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"1606"},"PeriodicalIF":3.1,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12522280/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145290916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tramadol combined with local anesthesia for postoperative pain in third molar surgery.","authors":"İbrahim Murat Afat, Onur Gönül, Tülin Satılmış","doi":"10.1186/s12903-025-07011-0","DOIUrl":"10.1186/s12903-025-07011-0","url":null,"abstract":"<p><strong>Background: </strong>Postoperative pain is a significant challenge in oral surgery. Tramadol exhibits both systemic and local analgesic effects, with proven efficacy in combination with local anesthetics.</p><p><strong>Purpose: </strong>This study evaluated the efficacy of local anesthetics combined with tramadol in reducing pain and analgesic use after third molar surgery.</p><p><strong>Study design, setting, sample: </strong>This randomized, double-blind trial included ASA I-II patients aged 18-50 years and weighing 70-80 kg who were undergoing impacted third molar surgery. Patients requiring extra anesthesia, those with tramadol hypersensitivity, or those who recently used sedatives were excluded.</p><p><strong>Independent variables: </strong>Two local anesthetic solutions were compared: the LT group (tramadol and articaine with epinephrine) and the LA group (articaine with epinephrine, control).</p><p><strong>Main outcome variable: </strong>Postoperative pain was measured as the primary outcome via a visual analog scale (VAS) at multiple time points (10 min and 1, 2, 4, 6, 12, 24 and 48 h postsurgery). The secondary outcomes included the timing of the first analgesic intake and the total number of analgesic doses consumed within 48 h.</p><p><strong>Covariates: </strong>The covariates included age, sex, BMI, surgical duration, and adverse effects (nausea, vomiting, burning).</p><p><strong>Analyses: </strong>Age and surgical duration were analyzed with t tests; VAS scores and analgesic use were analyzed with Mann-Whitney U tests; and categorical data were analyzed with Fisher's exact test or Yates' correction (p < 0.01).</p><p><strong>Results: </strong>Sixty patients were randomized into the LT (n = 30) and LA (n = 30) groups. Age, sex, and BMI distributions were similar between the groups. VAS pain scores were lower in the LT group at 1, 2, and 6 h (mean difference: -4.9, -1.9, and - 1.4; p < 0.01) but higher at 4 h (mean difference: 1.5; p < 0.01). The LT group required their first analgesic later (5.2 ± 0.8 vs. 2.0 ± 0.6 h; mean difference: 3.1; p < 0.01) and consumed fewer analgesics (1.8 ± 0.5 vs. 3.6 ± 0.8 doses; mean difference: -1.8; p < 0.01). A transient higher VAS score was observed at 4 h in the LT group, likely reflecting delayed analgesic use. Adverse effects were minimal and not significantly different between groups.</p><p><strong>Conclusion and relevance: </strong>Local anesthetics combined with tramadol reduce pain and analgesic use after third molar surgery. This strategy improves recovery and warrants further research for broader applications.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov NCT05614440, Date of registration 14 November 2022.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"1610"},"PeriodicalIF":3.1,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12522900/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145291000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond virality: evaluating evidence-based content delivery in social media-based pediatric orthodontic education.","authors":"Jinmei Wu, Zhili Dong, Peiqi Lin, Yiran Luo, Liping Wu, Xin'an Li","doi":"10.1186/s12903-025-06998-w","DOIUrl":"10.1186/s12903-025-06998-w","url":null,"abstract":"","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"1603"},"PeriodicalIF":3.1,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12519754/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145285303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and validation of the participation in treatment decision-making scale for adults with malocclusion (PTDMS-AM).","authors":"Xiangying Hu, Bixia Wang, Ting Pan, Weijun Yuan, Lili Hou","doi":"10.1186/s12903-025-06825-2","DOIUrl":"10.1186/s12903-025-06825-2","url":null,"abstract":"<p><strong>Background: </strong>Participation in decision-making is crucial for patients with malocclusion. It is important to assess the extent to which patients are actively involved in such decision-making. Therefore, this study developed an instrument that evaluates patient participation in treatment decision-making among adults with malocclusion and tested its reliability and validity.</p><p><strong>Methods: </strong>A cross-sectional instrument-development methodological approach was adopted. Guided by the concept of participation and shared decision-making theory, an initial scale was developed through literature analysis, qualitative interviews, expert evaluation, and a pre-survey. From September to December 2023, 257 patients from three tertiary general hospitals in Shanghai were selected for a questionnaire survey, item analysis, and exploratory factor analysis. From January to May 2024, 269 patients from these hospitals were selected to conduct a questionnaire survey for confirmatory factor analysis and criterion-related validity.</p><p><strong>Results: </strong>The final scale included 21 items across three dimensions. The Cronbach's α coefficient was 0.953; split-half reliability, test-retest reliability, and the scale level content validity index were 0.957, 0.885, and 0.926 respectively. The correlation coefficients between each dimension and the total score of the scale and SDM-9 scores were 0.590-0.650 (P < 0.05). Exploratory factor analysis extracted three common factors; the Kaiser-Meyer-Olkin value was 0.974 and the Bartlett's sphericity test χ² value was 5652.33 (P < 0.001); the cumulative variance explained was 60.920%. The fit indices of the scale model tested in the confirmatory factor analysis were as follows: χ²/df = 1.059, RMR = 0.033, GFI = 0.936, CFI = 0.968, TLI = 0.964, NFI = 0.641, RMSEA = 0.015. Confirmatory factor analysis revealed that the scale's factor structure was stable.</p><p><strong>Conclusions: </strong>This instrument is a reliable and valid measurement tool for assessing adult patients' level of participation in decision-making regarding treatment for malocclusion.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"1602"},"PeriodicalIF":3.1,"publicationDate":"2025-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12515386/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145273743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient satisfaction and oral health-related quality of life for prefabricated teeth versus CAD-CAM milled acrylic resin denture teeth. A crossover clinical trial.","authors":"Heba Wageh Abozaed, Sarah Abdelaal Ali, Aisha Zakaria Mostafa","doi":"10.1186/s12903-025-06834-1","DOIUrl":"10.1186/s12903-025-06834-1","url":null,"abstract":"<p><strong>Background: </strong>Artificial teeth replicate the appearance of natural teeth and restore proper alignment, oral function, and speech. Over the years, dental materials and prosthetic design advancements have transformed the creation and effectiveness of complete denture teeth. This evolution showcases a continued commitment to developing materials and methods that enhance the comfort, functionality, and visual appeal for patients without teeth. This study evaluated and compared patient satisfaction and oral health-related quality of life (OHRQL) between prefabricated and computer-aided design and computer-aided manufacturing (CAD-CAM) milled acrylic resin denture teeth.</p><p><strong>Materials and methods: </strong>This crossover clinical study included 10 completely edentulous patients rehabilitated with complete dentures (CDs). Two types of acrylic resin teeth were used: prefabricated and CAD-CAM-milled artificial teeth. Crossover design is a research method that minimizes variability among participants by assessing the impact of various treatments on the same individual. This methodological approach facilitates the identification and measurement of the treatment effects. Following six months of complete denture wear, patient satisfaction and oral health-related quality of life were evaluated using the Visual Analogue Scale (VAS) and the Oral Health Impact Profile (OHIP-EDENT-19). Statistical analysis was conducted using the Wilcoxon signed-rank test in SPSS software, with statistical significance established at P < 0.05.</p><p><strong>Results: </strong>There was no statistical difference between the groups in the total VAS scores and items, except for chewing efficiency, with a P-value of 0.035, where CAD-CAM milled resin teeth had statistically higher scores. In contrast, prefabricated teeth had a statistically higher aesthetic score (p = 0.033). Regarding OHIP-EDENT-19, many items showed no statistical differences between the two groups, except for functional limitations and difficulty chewing, which had a P-value of 0.05 and were statistically higher in prefabricated teeth. In contrast, psychological discomfort (P = 0.034) and social disability (P = 0.046) had significantly higher scores for the CAD-CAM milled teeth.</p><p><strong>Conclusion: </strong>This study suggests that prefabricated and CAD-CAM milled resin teeth are viable treatment options for complete dentures. Prefabricated teeth are advisable when aesthetics is the patient's primary concern. Conversely, CAD-CAM milled teeth are preferable when chewing efficiency is the primary concern.</p><p><strong>Clinical trial registration: </strong>Registered at www.</p><p><strong>Clinicaltrials: </strong>gov : (NCT06179615) (11-12-2023).</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"1601"},"PeriodicalIF":3.1,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12514817/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145273719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of nanosized graphene oxide on the rheological, physical, mechanical, and antibacterial properties of condensation silicone dental impression materials.","authors":"Mohsen Fakoori, Saeed Hesaraki, Nader Nezafati, Majid Ghiass","doi":"10.1186/s12903-025-06997-x","DOIUrl":"10.1186/s12903-025-06997-x","url":null,"abstract":"<p><strong>Background: </strong>Condensation silicone dental impression materials are widely used but are limited by polymerization shrinkage, poor wettability, and susceptibility to bacterial contamination. This study evaluates the incorporation of nanosized graphene oxide (GO) as a multifunctional additive to address these issues.</p><p><strong>Methods: </strong>GO was incorporated into a self-formulated silicone matrix at concentrations from 0 to 0.5 vol%. The resulting composites were comprehensively characterized for their physical, mechanical, rheological, and antibacterial properties.</p><p><strong>Results: </strong>The incorporation of GO yielded significant, concentration-dependent improvements. Dimensional stability was markedly enhanced, with as little as 0.05% GO reducing 12-hour shrinkage from over 2% to just 0.06%. Handling characteristics were improved, with prolonged working times and enhanced flowability. Mechanical properties were also significantly affected, enabling targeted modification of hardness and flexibility; 0.1% GO increased Shore A hardness by over 14%, while 0.3% GO increased elongation at break by over 55%, demonstrating the ability to optimize the material for either rigidity or flexibility. Surface wettability was improved, with the contact angle decreasing by nearly 19%. Crucially, the composites demonstrated potent antibacterial activity, with 0.2% GO achieving up to 40% efficacy against S. mutans.</p><p><strong>Conclusion: </strong>GO is a highly effective multifunctional additive that simultaneously addresses the key limitations of condensation silicones by enhancing dimensional accuracy, tailoring mechanical properties, improving handling, and increasing hygienic safety. These findings highlight the potential for developing a new class of advanced, high-performance dental impression materials.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"1599"},"PeriodicalIF":3.1,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12512872/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145273826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}