BMC Oral Health最新文献

{"title":"The association of third molars with mandibular incisor crowding in a group of the Yemeni population in Sana'a city: cone-beam computed tomography.","authors":"Khalid Aldhorae, Ramy Ishaq, Salah Alhaidary, Ashraf Mohammed Alhumaidi, Mohammed M Al Moaleem, Ghamdan Al Harazi, Naela Al-Mogahed, Hani Homaid, Sadam Ahmed Elayah","doi":"10.1186/s12903-025-05733-9","DOIUrl":"https://doi.org/10.1186/s12903-025-05733-9","url":null,"abstract":"<p><strong>Background: </strong>Multiple factors contribute to mandibular incisor crowding. However, the role of wisdom teeth in these irregularities remains a controversial issue among clinicians. Therefore, this study aimed to determine the potential association between mandibular incisor crowding and the presence or absence of lower wisdom teeth using CBCT image analysis.</p><p><strong>Materials and methods: </strong>A total of 64 CBCT images of adult patients were recruited. These CBCT images were classified into two groups according to the presence or absence of the lower wisdom teeth on the panoramic view. After the classification, the severity of crowding was calculated by utilizing Little's irregularity index. Points such as A point, Nasion, and B point (Supramentale) were identified on the software program. The significance level was set at P < 0.05.</p><p><strong>Results: </strong>There was no statistically significant correlation (P = 0.780) in the crowding of the mandibular incisor among the groups with the presence or absence of the lower wisdom teeth. Group 1 (with wisdom teeth) was 5.85 ± 4.05 mm, classified as a moderate irregularity; similarly, group 2 (without wisdom teeth) showed moderate irregularity with a mean value of 5.32 ± 3.12 mm. There was an incisor crowding with a severe irregularity in 18 patients (28.1%), a minimal irregularity in 15 patients (23.4%), a moderate irregularity in 14 patients (21.9%), a very severe irregularity in 10 patients (15.6%), and a perfect alignment in 7 patients (10.9%).</p><p><strong>Conclusions: </strong>The presence and absence of lower wisdom teeth do not influence the mandibular incisor crowding.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"410"},"PeriodicalIF":2.6,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143668813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does reducing the acid-etching time increase the micro-tensile bond strength of a bulk fill composite to dentin using different universal adhesives?","authors":"Elif Öztürk, Omer Taha Meric, Dilek Helvacioglu-Yigit","doi":"10.1186/s12903-025-05602-5","DOIUrl":"https://doi.org/10.1186/s12903-025-05602-5","url":null,"abstract":"<p><strong>Objectives: </strong>The objective of this in vitro study was to evaluate whether a reduced phosphoric acid etching time would have an impact on the microtensile bond strength (µTBS) of different universal adhesives to dentin using a bulk-fill composite.</p><p><strong>Methods: </strong>Forty-eight freshly extracted non-carious human molars were immersed in acrylic resin and cut to a height of 4 mm from the highest tubercle crest towards the cervical region. Dentin surfaces were subjected to 37% phosphoric acid pretreatment for 0, 3, or 15 s (s), rinsed with water for 20 s and gently dried, and wet-bonded. Two universal adhesives (Single Bond Universal, 3 M-ESPE; Adhese Universal, Ivoclar Vivadent) were used in this study. The Tofflemire matrix was added to each tooth, and a bulk-fill resin composite (Tetric EvoCeram Bulk-Fill, Ivoclar Vivadent) with a thickness of 5 mm was applied. The tooth composite blocks were cured using a light-emitting diode unit for either 20-40 s. Twelve groups were included (four teeth per group). All samples were immersed in distilled water for 24 h at 37°C. The samples were sectioned under water cooling to obtain multiple sticks approximately 1.0 × 1.0 × 8 mm³ in size using a non-trimming technique with water cooling. The µTBS test was performed (n = 20 sticks for each group). The data were analysed via a Welch analysis of variance (ANOVA) and the Games-Howell post hoc test (SPSS 23.0). The interactions between the three factors were analysed with a three-way ANOVA.</p><p><strong>Results: </strong>Significant differences were observed among the experimental groups (p < 0.05). Both adhesives exhibited the highest bond-strength values in the groups for which acid was applied to the dentin for 3 s and the composite resin was light-cured for 40 s, resulting in statistically significantly higher values for these two groups compared with the other groups (p < 0.05).</p><p><strong>Conclusion: </strong>Reducing the etching time to 3 s compared to the traditional etching time of 15 s increased the micro-tensile bond strength of the bulk-fill composite to dentin using universal adhesives.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"412"},"PeriodicalIF":2.6,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143668743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of alloplastic materials, biologics, and their combinations, along with defect characteristics, on short-term intrabony defect surgical treatment outcomes: a systematic review and network meta-analysis.","authors":"Khanti Rattanpornsompong, Kantapon Rattanaprukskul, Sikharate Prachanukoon, Kanokrat Sriwangyang, Mawika Rinkrathok, Junji Tagami, Thantrira Porntaveetus","doi":"10.1186/s12903-025-05782-0","DOIUrl":"10.1186/s12903-025-05782-0","url":null,"abstract":"<p><strong>Background: </strong>Treating periodontal intrabony defects remains challenging, alloplast materials and biologics are increasingly utilized to improve regeneration outcomes. However, comparative efficacy on alloplast materials remains limited. This study aimed to evaluate the effectiveness of alloplastic materials, both alone and combined with biologics, in treating periodontal defects.</p><p><strong>Methods: </strong>A systematic search of PubMed, Scopus, and CENTRAL identified 74 eligible randomized controlled trials. Meta-analysis assessed data heterogeneity based on defect depth and morphology, classifying defects by wall configuration. Network meta-analysis compared clinical attachment level (CAL) gain, probing depth (PD) reduction, and radiographic linear bone (RLB) gain up to 12 months. Risk of bias was evaluated using the Cochrane Risk of Bias 2 tool, and confidence in network meta-analysis was graded using CINeMA.</p><p><strong>Results: </strong>Defect depth and morphology significantly impacted heterogeneity outcomes at 6 months, but by 12 months, differences across treatments were less significant. Biphasic calcium phosphate (BCP) and nanocrystalline hydroxyapatite (nHA) showed notable improvements in CAL gain, PD reduction, and RLB gain. Combining nHA with platelet-rich fibrin (PRF) outperformed open flap debridement (mean differences at 6 months for CAL gain: 1.37 mm, PD reduction: 1.52 mm and RLB gain: 1.39 mm). SUCRA ranked bioglass and BCP highest for single treatments, while bioglass with platelet-rich plasma and nHA + PRF excelled among combinations.</p><p><strong>Conclusions: </strong>Alloplastic materials, particularly BCP and nHA, significantly enhance periodontal treatment outcomes, especially when combined with biologics like PRF. Defect depth and morphology influence treatment efficacy at 6 months, though by 12 months, treatment outcomes converge, underscoring the value of early, tailored strategies in periodontal therapy.</p><p><strong>Trial registration: </strong>Not applicable.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"413"},"PeriodicalIF":2.6,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143668838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics of phase 4 clinical trials on Dental Caries registered at Clinicaltrials.gov.","authors":"Kerim Safa Kul, Muhammet Kerim Ayar","doi":"10.1186/s12903-025-05662-7","DOIUrl":"https://doi.org/10.1186/s12903-025-05662-7","url":null,"abstract":"<p><strong>Background: </strong>Dental caries, a widespread chronic oral disease, is caused by multiple factors including microorganisms, genetic predisposition. Despite being preventable, it poses a significant global burden. This study reviews all phase 4 clinical trials on dental caries registered at ClinicalTrials.gov to provide a comprehensive overview of their characteristics.</p><p><strong>Methods: </strong>A search was conducted on the ClinicalTrials.gov database using keywords. The registration data for all relevant phase 4 studies concerning 'Dental Caries' were retrieved. This search was conducted on the 23rd of January, 2024.</p><p><strong>Results: </strong>The analysis included 58 phase 4 clinical trials, with most studies (67.2%) reporting complete data. The majority (63.8%) had fewer than 100 participants, and the predominant sponsors were medical institutions (77.6%). Geographically, the highest percentage of studies were conducted in South America (24.1%), with the lowest in North America (10.3%). Interventional trials primarily focused on treatment (51.7%) and prevention (41.4%), with a significant portion being randomized (93.1%). Blinding varied, with single and double blinding each used in 25.9% of studies. Drug interventions were the most common (60.6%), followed by other categories such as dietary supplements and procedures. Among drug interventions, agents containing fluoride were the largest category, accounting for 52.6% of the trials. Fluoride varnishes and silver diamine fluoride were the most frequently evaluated. Sedatives and pain relievers constituted 15.7% of the trials, with midazolam and ketamine being predominant. Other drugs accounted for 23.2% of the trials, featuring diverse substances such as inactivated poliovirus vaccine and xylitol. Dental materials and operative treatments made up 29.5% of the trials, with resin and fissure sealants being the most commonly evaluated.</p><p><strong>Conclusion: </strong>This analysis of phase 4 clinical trials highlighted fluoride as the most studied intervention for dental caries prevention. The analysis also revealed a need for further research on non-fluoride interventions and emphasized the importance of using evidence-based practices in dental care for improved oral health outcomes.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"411"},"PeriodicalIF":2.6,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143668739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of dental health and salivary microbiota characteristics of children with visual impairment in Guangzhou, China.","authors":"Qiong Feng, Wengyan Huang, Xuedan Zhao, Ting Sheng, Bo Peng, Si Meng, Weijia Liu, Lihong Ge, Lijing Wang, Janak Lal Pathak, Qianzhou Jiang, Rong Lin, Sujuan Zeng","doi":"10.1186/s12903-025-05713-z","DOIUrl":"10.1186/s12903-025-05713-z","url":null,"abstract":"<p><strong>Background: </strong>The prevalence of visual impairment (VS) among children in China is increasing. The oral microbiome is crucial for maintaining homeostasis and health. This study aimed to investigate the oral health and hygiene habits of children with VS in Guangzhou and explore the differences in salivary microbiota (SM) between children with VS and healthy vision (HS).</p><p><strong>Method: </strong>This study included oral health examinations and surveys of oral hygiene habits among 101 children with VS. Saliva samples from 20 children with VS and 20 with HS were analysed for oral microbiota. The 16s rRNA V3-V4 regions were sequenced using the Illumina MiSeq platform and operational taxonomic units were clustered using QIIME for statistical analysis.</p><p><strong>Results: </strong>Inadequate oral hygiene was observed among 101 children with VS, aged 6-16, who displayed a high caries rate of 92.1%. There was no significant difference in the overall composition of the salivary microbiota between the two groups. HS group had a higher abundance of Bacillota, Patescibacteria, and Spirochaetota at the phylum level; Bacilli, Negativicutes, and Saccharimonadia at the class level; and Streptococcus at the genus level. In contrast, VS group showed a greater abundance of Actinomycetota, Bacteroidota, Pseudomonadota, and Fusobacteriota (at the phylum level) and Actinomycetia, Bacteroidia, Gammaproteobacteria, Fusobacteriia, and Clostridia (at the class level), along with Rothia, Neisseria, Veillonella, Prevotella_7, Actinomyces, Leptotrichia, and Lactobacillales (at the genus level). Actinomycetota was significantly and positively correlated with gingivitis and dental caries, and Streptococcus salivarius was more abundant in children with VS.</p><p><strong>Conclusion: </strong>This study underscores the importance of improving oral healthcare for schoolchildren with VS in Guangzhou, China and provides valuable insights into the characteristics of the salivary microbiota of this population, identifying potential targets for interventions aimed at enhancing oral health.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"408"},"PeriodicalIF":2.6,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924837/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In vitro assessment of the accuracy of two intra-oral scanners for post space scanning in a fully digital workflow.","authors":"Mennatallah Wahba, Reham Said ElBasty","doi":"10.1186/s12903-025-05723-x","DOIUrl":"10.1186/s12903-025-05723-x","url":null,"abstract":"<p><strong>Background: </strong>With the rapid advancements in computer-aided imaging, the potential for chairside fabrication of custom-made posts utilizing intraoral scanners may offer a reliable alternative to traditional physical impressions. Accordingly, this study aimed to evaluate the accuracy (trueness and precision) of two intra-oral scanners when different post space diameters were employed. Additionally, the scan depth of each intra-oral scanner (IOS) was assessed.</p><p><strong>Methods: </strong>An endodontically treated mandibular canine was inserted in a printed typodont model and prepared with two post-space diameters; a small one (1.5 mm) and a large one (2 mm). Polyvinyl siloxane impressions for the two post-space diameters were taken and then scanned with an extra-oral scanner to serve as reference scans. Each post-space diameter was scanned using CEREC Primescan (n = 8) and Medit i700 (n = 8) intra-oral scanners. Standard tessellation language (STL) files of all intra-oral and extra-oral scans were uploaded to a 3D matching program to evaluate trueness, precision, and post-space length difference. Statistical analysis was performed using different tests for parametric and non-parametric data. The significance level was set at P < 0.05.</p><p><strong>Results: </strong>Regarding the effect of the IOS and the effect of the post-space diameter, both Medit i700 and the small diameter groups using both scanners showed significantly higher root mean square (RMS) values when evaluating trueness. For precision, Medit i700 showed a significantly higher RMS value in the large diameter group. Medit i700 showed a significantly higher difference in post-space length than Primescan in both diameters. Primescan recorded a zero difference in the large diameter group compared to the reference scan.</p><p><strong>Conclusions: </strong>The IOS type and the post-space diameter influenced the scan accuracy and the depth of the scan. Accuracy results were superior when Primescan was implemented for scanning the large diameter post-space subgroup.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"407"},"PeriodicalIF":2.6,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924774/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between the indicators of insulin resistance and periodontitis: a study using data from the National Health and Nutrition Examination Survey 2009-2014.","authors":"Yiyuan Lang, Xin Song, Yan Chen, Han Mei, Chengyu Wu, Rui Zhang, Changao Xue","doi":"10.1186/s12903-025-05752-6","DOIUrl":"10.1186/s12903-025-05752-6","url":null,"abstract":"<p><strong>Background: </strong>The rising obesity rates are accompanied by an increasing prevalence of insulin resistance (IR) associated with obesity. To ascertain the best index for replacing IR, this study aimed to investigate the possible association between IR, which was assessed using the Homeostatic Model Assessment of Insulin Resistance (HOMA-IR), and the triglyceride-glucose (TyG) index and its derived indexes and periodontitis.</p><p><strong>Methods: </strong>The association between the indicators of IR and periodontitis was assessed via multivariate-adjusted logistic regression analyses using data from the National Health and Nutrition Examination Survey (NHANES) 2009-2014. In addition, subgroup analyses and receiver operating characteristic curve analyses were conducted to explore possible influencing factors.</p><p><strong>Results: </strong>Our study encompassed 1,588 participants, and 41.0% were diagnosed with periodontitis. Based on the multivariate logistic regression analysis, a higher TyG-waist-to-height ratio (WHtR) (odds ratio [OR] = 1.14, 95% confidence interval [CI]: 1.02-1.27, P = 0.0244) and HOMA-IR score (OR = 1.00, 95% CI: 1.00-1.00, P = 0.0028) were associated with an increased risk of periodontitis. Conversely, the TyG index, TyG-adjusted for body mass index, and TyG-adjusted for waist circumference (WC) were not associated with periodontitis. According to further subgroup analyses and interaction result analyses, sex affected the association between the TyG index, TyG-WC, and TyG-WHtR and periodontitis (P < 0.05 for interaction). Moreover, the influence of age regulated the association between periodontitis and both TyG and HOMA-IR score. In terms of diagnostic accuracy, the area under the receiver operating characteristic curve analysis revealed that HOMA-IR score and TyG-WHtR slightly outperformed the TyG index, TyG-body mass index, and TyG-WC. Thus, they can be robust markers for assessing IR-related periodontitis risk.</p><p><strong>Conclusion: </strong>A consistent and positive association was found between HOMA-IR score and TyG-WHtR and the odds of periodontitis prevalence. Hence, HOMA-IR score and TyG-WHtR were significantly associated with periodontitis in this cross-sectional study. However, prospective studies are needed to determine whether higher TyG-waist-to-height ratio and HOMA-IR score can predict the occurrence of periodontitis.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"404"},"PeriodicalIF":2.6,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924845/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence trends and projections of lip and oral cavity cancer in China 1990-2021: an age-period-cohort and decomposition analysis.","authors":"Long Xie, Chun-Ming Huang, Yan-Li Song, Zhe Shao, Zheng-Jun Shang","doi":"10.1186/s12903-025-05764-2","DOIUrl":"10.1186/s12903-025-05764-2","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the historical trends, underlying causes, and future projections of lip and oral cavity cancer (LOCC) incidence in China.</p><p><strong>Methods: </strong>Annual cases and age-standardized incidence rates (ASIR) for LOCC in China from 1990 to 2021 were extracted from the Global Burden of Disease (GBD) 2021 study. Age-Period-Cohort (APC) models were employed to assess the effects of age, period, and cohort. Bayesian APC models were applied to project future incidence trends, and decomposition analysis was conducted to identify factors influencing incidence.</p><p><strong>Result: </strong>From 1990 to 2021, the cases and ASIR of LOCC increased substantially in male and slightly in female. The ASIR and number of cases in male were higher than that in female during the study period. The APC model showed that the net drift of ASIR in males and females during the study period was 2.34% (95% confidence interval [CI]: 2.10% to 2.59%) and 0.26% (95% CI: 0.13 to 0.39), respectively. LOCC incidence increased the fastest among males and females aged 25-29 years. The incidence of LOCC in male and female increased with age, reaching its peak in the age group of 90-94 years (73.35/100,000 and 11.14/ 100,000, respectively). The period effect showed an increasing trend, while the birth cohort effect showed a decreasing trend. Predictions show that the incidence and cases of LOCC will continue to rise. Population growth, ageing and epidemiological factors in both male and female contributed to the rise of LOCC cases, except for a decrease in the period 1997-2013 due to changing epidemiological factors in female.</p><p><strong>Conclusion: </strong>The increasing trend of LOCC in China is closely related to age, period and cohort. Future projections emphasize the need for targeted prevention focusing on high-risk groups and modifiable factors.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"406"},"PeriodicalIF":2.6,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924705/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Subperiosteal Abscess following tooth infection in early childhood: a case report.","authors":"Lara Ibrahim Ghannam, Rama Ahmad Abu Doush, Rita Kifah Yacoub, Zeina Amro, Jafar Ayesh","doi":"10.1186/s12903-025-05738-4","DOIUrl":"10.1186/s12903-025-05738-4","url":null,"abstract":"","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"409"},"PeriodicalIF":2.6,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924749/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between trace elements and dental caries in the USA: analysis of data from serial cross-sectional surveys, 2010-2016.","authors":"Taowu Chen, Yulin Chen, Heng Wang, Xueqing Li, Xin Guo, Hong Tan, Xiaoyan Zhang, Chunhui Li, Rui Shi, Chen Sun","doi":"10.1186/s12903-025-05763-3","DOIUrl":"10.1186/s12903-025-05763-3","url":null,"abstract":"<p><strong>Background: </strong>Dental caries is a localized deterioration of hard tissues caused by acidic by-products of bacterial fermentation of dietary carbohydrates. However, except for fluoride, there were few studies focusing on the direct association between other trace elements. This study aimed to explore how other trace elements affect dental caries.</p><p><strong>Methods: </strong>Data from 10,426 individuals were collected from the National Health and Nutrition Examination Survey (NHANES) during the 2010-2016 cycle. The sample was restricted to individuals aged 20 years or older who had complete clinical oral examination data, and who had also completed blood (N = 10,086), serum (N = 5,152), or urine tests (N = 5,297). These three groups were weighted to represent multi-year data. The effects of 20 trace elements on dental caries experience were investigated using quartiles of continuous variables and weighted multivariate logistic regression models.</p><p><strong>Results: </strong>The analysis revealed significant differences in trace elements (lead, cadmium, mercury, molybdenum, tin, and tungsten) between individuals with no dental caries experience and those with dental caries experience (P < 0.05). Adjusted results from the weighted multivariate logistic regression model showed that the odds ratios (OR) for following trace elements were significantly positively associated with dental caries experience: lead (OR = 1.0105; 95% CI 1.0030-1.0181; P = 0.0077), cobalt (OR = 1.0048; 95% CI 1.001-1.0087; P = 0.0154), cesium (OR = 1.0028; 95% CI 1.0011-1.0046; P = 0.0027), and arsenic (OR = 1.0002; 95% CI 1-1.0004; P = 0.0244), while iron (OR = 0.9974; 95% CI 0.9954-0.9994; P = 0.0116) showed the negative association.</p><p><strong>Conclusion: </strong>The results of this cross-sectional study conducted on the U.S. population identified a statistically significant positive association between dental caries and trace elements, including lead, cobalt, cesium, and arsenic, while a negative association was observed with iron.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"405"},"PeriodicalIF":2.6,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924794/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}