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Effect of different bonding agents and airborne-particle abrasion on shear bond strength and mode of failure between 3D-printed denture tooth-colored specimens and 3D-printed denture bases. 不同粘结剂及空气颗粒磨损对3d打印义齿彩色标本与3d打印义齿基托剪切粘结强度及破坏模式的影响
IF 3.8 2区 医学
BMC Oral Health Pub Date : 2026-11-05 DOI: 10.1186/s12903-026-10075-1
Amany Mostafa Saad Farahat, Mahmoud Amin Faty
{"title":"Effect of different bonding agents and airborne-particle abrasion on shear bond strength and mode of failure between 3D-printed denture tooth-colored specimens and 3D-printed denture bases.","authors":"Amany Mostafa Saad Farahat, Mahmoud Amin Faty","doi":"10.1186/s12903-026-10075-1","DOIUrl":"10.1186/s12903-026-10075-1","url":null,"abstract":"<p><strong>Background: </strong>In conventionally fabricated dentures, debonding between the denture teeth and the denture base accounts for 22 to 30% of all denture repairs, with failures predominantly occurring in the anterior region. Various surface treatments and bonding protocols have been proposed to enhance adhesion between denture teeth and denture base; however, reliable bonding between three-dimensional (3D)-printed denture teeth and denture bases remains a challenge, and evidence regarding the influence of bonding strategies and surface treatment protocols is limited.</p><p><strong>Methods: </strong>3D-printed tooth-colored and denture base specimens (n = 72) were fabricated and allocated into 3 bonding agent groups (n = 24); in each group, the tooth-colored specimens were subdivided into two subgroups. In subgroup A, the undersurface of the tooth-colored specimens was air-abraded, while in subgroup B, it remained untreated. The bonding agent in the first group was 3D printing denture base liquid resin; in the second group, a universal adhesive; and in the third group, a resin cement. All the specimens were subjected to thermocycling for 5000 cycles, after which shear bond strength was evaluated using a universal testing machine. The mode of failure was evaluated under a stereomicroscope. Two-way analysis of variance was used to assess the effect of the bonding agents, surface treatment, and their interactions. Pairwise comparisons were performed utilizing pairwise t-tests with Bonferroni correction. Failure mode distributions were evaluated using the Fisher's exact test.</p><p><strong>Results: </strong>The null hypothesis was partially rejected. Two-way ANOVA revealed significant main effects of bonding agent (P < 0.001); neither surface treatment (P = 0.881) nor the bonding agent-surface treatment interaction (P = 0.146) reached statistical significance. The highest shear bond strength was reported in the liquid resin subgroups 9.04 ± 2.27 and 8.39 ± 2.12, and the lowest shear bond strength was in the resin cement subgroups 5.12 ± 1.75 and 4.27 ± 1.46. Airborne-particle abrasion had no significant effect within any individual bonding agent (P = 0.438, P = 0.130, P = 0.315, respectively). Failure mode distribution differed significantly among the bonding protocols with and without air abrasion (P < 0.001). Airborne-particle abrasion significantly altered failure mode distributions for liquid resin (P < 0.001) and universal adhesive (P = 0.001), but not for resin cement.</p><p><strong>Conclusions: </strong>Under the tested conditions, liquid resin showed higher mean shear bond strength than universal adhesive and resin cement for bonding 3D-printed denture tooth-colored specimens and denture base, with a predominant cohesive failure mode. The effect of airborne-particle abrasion of the tooth-colored specimen-bonding surface did not significantly change shear bond strength within any individual group, but, resulted in a statistically si","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"26 1","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13737797/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149340714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of aging on marginal and internal adaptation of bulk-fill resin composites with different viscosities in class II restorations. 老化对不同粘度体积填充树脂复合材料ⅱ类修复体边缘适应性和内部适应性的影响
IF 3.8 2区 医学
BMC Oral Health Pub Date : 2026-11-05 DOI: 10.1186/s12903-026-10102-1
Asmaa Saad Elsaeed, Youniss Saleh Harp, Hamdi Hamama, Salah Hasab Mahmoud
{"title":"Effect of aging on marginal and internal adaptation of bulk-fill resin composites with different viscosities in class II restorations.","authors":"Asmaa Saad Elsaeed, Youniss Saleh Harp, Hamdi Hamama, Salah Hasab Mahmoud","doi":"10.1186/s12903-026-10102-1","DOIUrl":"10.1186/s12903-026-10102-1","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate and compare the effect of thermocycling and water storage on the marginal and internal adaptation of bulk-fill resin composites with different viscosities (No-cap low viscosity, thermoviscous, sonically activated, and conventional bulk-fill) in Class II restorations using scanning electron microscope.</p><p><strong>Materials and methods: </strong>Fifty-six sound molars were prepared with standardized class II cavities (occlusal depth:3.0 mm, bucco-lingual width: 3.0 mm, depth, proximal box: 3.0 mm bucco-lingual width, 1.5 mm axial depth, and gingival margin extended 1-mm below CEJ). They were assigned into four groups according to the material used (n = 14). For the marginal and internal adaptation test, half of the specimens in each group were tested after one week, however the remaining half were tested after 12 months of water storage and exposure to 10,000 thermal cycles between 5 and 55 °C. Replicas were made and evaluated for marginal and internal adaptation using a scanning electron microscope at different magnifications. Continuous margin percentage values (%CM) and Maximum gap width values (MGW) were statistically analyzed.</p><p><strong>Results: </strong>Aging did not significantly affect external % CM, internal % CM, or external MGW (p > 0.05). However, internal MGW values were significantly lower in immediate specimens compared with aged ones (p < 0.05). Among the tested composites, no significant differences were observed in external or internal % CM or external MGW (p > 0.05). Nevertheless, at the dentin gingival margin, lower-viscosity bulk-fill composites generally showed numerically lower internal MGW values than the high-viscosity bulk-fill composite. However, after Bonferroni adjustment, statistically significant differences were observed only between Flowable and Tetric and between SonicFill and Tetric (p < 0.05). Furthermore, a strong correlation was detected between external and internal adaptation parameters (%CM and MGW) (p < 0.05).</p><p><strong>Conclusion: </strong>Aging did not adverse effect %CM or external MGW but significantly increased internal MGW. Some lower-viscosity bulk-fill composites showed lower internal MGW values at the gingival margin than the high-viscosity composite under the conditions of this in vitro study.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"26 1","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13737557/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149332430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metformin modulates alveolar bone parameters and gene expression in streptozotocin-induced type 2 diabetic rats. 二甲双胍调节链脲佐菌素诱导的2型糖尿病大鼠牙槽骨参数和基因表达。
IF 3.8 2区 医学
BMC Oral Health Pub Date : 2026-11-05 DOI: 10.1186/s12903-026-10091-1
Israa Ahmed Radwan, Gamilah Al-Qadhi, Hanaa S Mansy, Sana Mostafa, Sara El Moshy
{"title":"Metformin modulates alveolar bone parameters and gene expression in streptozotocin-induced type 2 diabetic rats.","authors":"Israa Ahmed Radwan, Gamilah Al-Qadhi, Hanaa S Mansy, Sana Mostafa, Sara El Moshy","doi":"10.1186/s12903-026-10091-1","DOIUrl":"10.1186/s12903-026-10091-1","url":null,"abstract":"<p><strong>Background: </strong>Diabetes mellitus (DM) is linked with defective bone healing and metabolic disturbances that increase fracture risk. Although metformin (MET) is used traditionally as first-line treatment for type 2 diabetes (T2DM), its effectiveness in completely reversing diabetic bone homeostasis is uncertain. The present study was conducted to assess the short-term effect of MET on alveolar bone histological structure and osteoblastic gene expression in rats with streptozotocin (STZ)-induced type 2 diabetes mellitus (T2DM).</p><p><strong>Methods: </strong>Eighteen adult male Wistar rats were divided equally into three groups (n = 6/group): control group (non-diabetic) was injected with saline, STZ group (diabetic) received 10% fructose solution for 2 weeks followed by an injection of a single dose of STZ (40 mg/kg), and MET group (diabetic with MET-treatment) received 100 mg/kg/day MET for 30 days. Alveolar bone was assessed by histological and histomorphometric analysis, cone beam computed tomography (CBCT), and reverse transcription-polymerase chain reaction (RT-PCR) analysis of bone-related gene expression.</p><p><strong>Results: </strong>The STZ group showed pronounced decreases in total bone area, osteoblast area, and bone-related gene expression (RunX2, osteocalcin, COL1A1) compared to the control group. MET significantly improved these parameters compared to the STZ group.</p><p><strong>Conclusions: </strong>Metformin significantly increased total bone area and osteoblastic gene expression (Runx2, osteocalcin, and COL1A1) compared to untreated diabetic rats but did not fully restore them to control (non-diabetic) levels. These results suggest a partial protective effect of metformin in alveolar bone in this short-term T2DM rat model.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"26 1","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13737824/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149332441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Candida albicans adhesion, biofilm formation and gene expression on conventional, milled and 3D-printed denture base materials: an in vitro study. 白色念珠菌在常规、研磨和3d打印义齿基托材料上的粘附、生物膜形成和基因表达:一项体外研究。
IF 3.8 2区 医学
BMC Oral Health Pub Date : 2026-11-04 DOI: 10.1186/s12903-026-10345-y
Julia Roßbach, Christoph Sasse, Ralf Bürgers, Oskar Bunz
{"title":"Candida albicans adhesion, biofilm formation and gene expression on conventional, milled and 3D-printed denture base materials: an in vitro study.","authors":"Julia Roßbach, Christoph Sasse, Ralf Bürgers, Oskar Bunz","doi":"10.1186/s12903-026-10345-y","DOIUrl":"10.1186/s12903-026-10345-y","url":null,"abstract":"<p><strong>Background: </strong>Denture base materials are colonized by Candida albicans, and surface properties influence microbial adhesion. Evidence on subtractively and additively manufactured materials remains limited. This in vitro study examined surface characteristics of conventional, milled and 3D-printed denture base materials and their association with C. albicans adhesion, biofilm formation and gene expression.</p><p><strong>Methods: </strong>Specimens of eight conventional, milled and 3D-printed denture base materials were polished to an arithmetic surface roughness (R<sub>a</sub>) below 0.2 μm and characterized by surface free energy (SFE), scanning electron microscopy and energy-dispersive X-ray spectroscopy. Initial adhesion of C. albicans DSM 1386 (2 h) was quantified by fluorescence staining. For the materials with the highest and lowest adhesion (Temp Basic, Denture Gingiva Basic Mono), 24-h biofilm formation was quantified by crystal violet staining, and ALS3 and EFG1 expression by RT-qPCR after 2, 4 and 8 h, additionally in two oral clinical isolates. Data were analyzed using (Welch) ANOVA with post hoc tests and one-sample t-tests (α = 0.05).</p><p><strong>Results: </strong>Temp Basic showed a significantly lower SFE than all other materials (p ≤ 0.012) and the highest mean initial adhesion, which differed significantly from PalaXpress, V-Print dentbase and Denture Gingiva Basic Mono (p ≤ 0.018). Biofilm biomass after 24 h did not differ between Temp Basic and Denture Gingiva Basic Mono (p = 0.261). In the reference strain, ALS3 and EFG1 expression was significantly higher on Denture Gingiva Basic Mono after 4 h (p<sub>ALS3</sub> = 0.009; p<sub>EFG1</sub> = 0.038), but not after 28 h. Both clinical isolates likewise showed higher expression after 4 h, without significance in clinical isolate 1; clinical isolate 2 was tested in a single experiment.</p><p><strong>Conclusions: </strong>Within the limitations of this in vitro study, SFE alone did not explain material-dependent differences in initial C. albicans adhesion, and higher initial adhesion was not associated with greater biofilm biomass. ALS3 and EFG1 expression after 4 h was higher on Denture Gingiva Basic Mono, significantly in the reference strain and in the same direction in two clinical isolates. Confirmation under clinically relevant conditions, including a salivary pellicle and multispecies biofilms, is required.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"26 1","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13733116/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149332416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of acellular dermal matrix on peri-implant soft tissue phenotype and marginal bone loss following immediate implant placement in the anterior maxilla: a randomized controlled clinical trial. 脱细胞真皮基质对上颌前牙种植体即刻植入后种植体周围软组织表型和边缘骨丢失的影响:一项随机对照临床试验
IF 3.8 2区 医学
BMC Oral Health Pub Date : 2026-11-04 DOI: 10.1186/s12903-026-10072-4
Mai Ahmed Haggag, Mohammed Feheid Alrawooji, Amira M M Attia
{"title":"Influence of acellular dermal matrix on peri-implant soft tissue phenotype and marginal bone loss following immediate implant placement in the anterior maxilla: a randomized controlled clinical trial.","authors":"Mai Ahmed Haggag, Mohammed Feheid Alrawooji, Amira M M Attia","doi":"10.1186/s12903-026-10072-4","DOIUrl":"10.1186/s12903-026-10072-4","url":null,"abstract":"<p><strong>Background: </strong>Immediate implant placement in the anterior maxilla is associated with dimensional changes in both hard and soft tissues, which may compromise esthetic outcomes. This randomized controlled clinical trial aimed to evaluate the effect of acellular dermal matrix (ADM) on peri-implant soft tissue phenotype and marginal bone loss following immediate implant placement.</p><p><strong>Methods: </strong>Patients requiring replacement of non-restorable maxillary anterior teeth were randomly allocated into two equal groups. The control group received high-density polytetrafluoroethylene (d-PTFE) membrane coverage, while the study group received ADM. Clinical parameters, including keratinized mucosal width (KMW), mucosal thickness (MT), and supracrestal tissue height (STH), were assessed at 6 months. Plaque accumulation and bleeding were monitored using modified sulcus bleeding index (mSBI) and plaque index (PI) at 1, 2, and 3 months after prosthetic loading. Implant stability was measured at placement and after 6 months. Radiographic outcomes, including marginal bone loss (MBL) and bone width (BW), were assessed using fused CBCT images at baseline and 6 months. In the study group, ADM was inserted into facial and palatal pouches. The primary outcome was peri-implant soft-tissue phenotype at 6 months, assessed by KMW, MT, and STH.</p><p><strong>Results: </strong>Thirty-three patients were assessed for eligibility, and sixteen patients were randomly allocated into two equal groups (n = 8 per group). All implants survived without complications during follow-up. At 6 months, the study group demonstrated significantly greater keratinized mucosal width (5.9 ± 1.0 vs. 3.3 ± 0.6 mm, p < 0.001), mucosal thickness (1.8 ± 0.3 vs. 0.8 ± 0.3 mm, p < 0.001), and supracrestal tissue height (1.2 ± 0.3 vs. 0.8 ± 0.3 mm, p = 0.012) than the control group. No significant differences between groups were observed in mSBI or PI. Implant stability increased significantly in both groups, with higher values in the ADM group at 6 months (p = 0.010). The study group also exhibited significantly less marginal bone loss, whereas horizontal bone width reduction was comparable between groups.</p><p><strong>Conclusion: </strong>ADM was associated with improved peri-implant soft tissue phenotype and reduced marginal bone loss compared with d-PTFE membranes while maintaining comparable peri-implant health. These findings support the potential use of ADM during immediate implant placement in the anterior maxilla.</p><p><strong>Trial registration: </strong>The study was retrospectively registered and listed on www.</p><p><strong>Clinicaltrials: </strong>gov with registration number (NCT07573020) on 07-05-2026.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"26 1","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13737684/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149332434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical accuracy of transferring virtually planned zygomatic implant positions in severely atrophic maxilla: a single-arm study. 在严重萎缩上颌骨中转移虚拟计划颧骨植入物位置的临床准确性:一项单臂研究。
IF 3.8 2区 医学
BMC Oral Health Pub Date : 2026-11-03 DOI: 10.1186/s12903-026-10079-x
Mahmoud Mohamed Hassan Agha, Ahmed Abdelmohsen Younis Ahmed Ali, Mohamed Ahmed ElSholkamy, Amr Aly El Swify
{"title":"Clinical accuracy of transferring virtually planned zygomatic implant positions in severely atrophic maxilla: a single-arm study.","authors":"Mahmoud Mohamed Hassan Agha, Ahmed Abdelmohsen Younis Ahmed Ali, Mohamed Ahmed ElSholkamy, Amr Aly El Swify","doi":"10.1186/s12903-026-10079-x","DOIUrl":"10.1186/s12903-026-10079-x","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to evaluate the clinical accuracy of transferring virtually planned zygomatic implant positions in severely atrophic maxilla.</p><p><strong>Materials and methods: </strong>This clinical accuracy study included 24 participants with severely atrophic edentulous maxilla. All cases were digitally planned using cone-beam computed tomography (CBCT) and treated with bilateral zygomatic implants under general anesthesia, with additional anterior conventional implants. Postoperative CBCT was used to superimpose the actual implant positions onto the virtual plan and assess coronal and apical deviations.</p><p><strong>Results: </strong>A total of 48 zygomatic implants were placed in 24 participants. Three-dimensional superimposition of the preoperative virtual plans and postoperative CBCT scans demonstrated a mean coronal deviation of 1.917 ± 0.401 mm overall, with values of 1.989 ± 0.540 mm on the right side and 1.846 ± 0.160 mm on the left side. The overall mean apical deviation was 1.733 ± 0.429 mm, with values of 1.757 ± 0.172 mm on the right side and 1.709 ± 0.588 mm on the left side.</p><p><strong>Conclusions: </strong>Virtual surgical planning enabled the transfer of planned zygomatic implant positions with measurable coronal and apical deviations. These findings describe short-term positional accuracy and should not be interpreted as evidence of long-term implant stability, treatment efficacy, or overall safety.</p><p><strong>Trial registration: </strong>Trial was retrospectively registered on 31/03/2023 at Pan African Clinical Trials Registry ( https://pactr.samrc.ac.za ) (ID: PACTR202603707948061) under the following link: https://pactr.samrc.ac.za/TrialDisplay.aspx?TrialID=40945 .</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"26 1","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13733075/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149332417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of oral mucosal lesions among smokers based on gender: a bicentric cross-sectional study in Egypt. 基于性别的吸烟者口腔黏膜病变患病率:埃及的一项双中心横断面研究。
IF 3.8 2区 医学
BMC Oral Health Pub Date : 2026-11-03 DOI: 10.1186/s12903-026-10040-y
Dalia Ghalwash, Fat'heya M Zahran
{"title":"Prevalence of oral mucosal lesions among smokers based on gender: a bicentric cross-sectional study in Egypt.","authors":"Dalia Ghalwash, Fat'heya M Zahran","doi":"10.1186/s12903-026-10040-y","DOIUrl":"10.1186/s12903-026-10040-y","url":null,"abstract":"<p><strong>Background: </strong>Smoking is a major risk factor for developing various types of oral mucosal lesions (OMLs), including benign and potentially malignant lesions. However, scarce data is available concerning gender differences regarding the prevalence of oral mucosal lesions in smokers worldwide. Accordingly, this study assesses the prevalence and types of OMLs among male smokers compared to female smokers in an Egyptian population.</p><p><strong>Methods: </strong>This hospital-based cross-sectional study included 300 male and 300 female smokers. All participants underwent a thorough case history review and a comprehensive clinical examination.</p><p><strong>Results: </strong>The overall prevalence of oral lesions was significantly higher in males (75%) than in females (52%). Increased tongue coating, black hairy tongue, leukoedema, and smoker's palate were found in males more than in females, with a statistically significant difference. Leukoplakia, a potentially malignant disorder, showed an odds ratio in males more than twice that of females. In contrast, males were found to have a significantly lower risk of developing smokers' melanosis than females.</p><p><strong>Conclusion: </strong>Both males and females manifest the same types of oral mucosal lesions in relation to smoking; however, males have an overall significantly higher prevalence of such lesions, with a higher odds ratio to develop certain types, including leukoplakia. Hence, gender-specific awareness programs are needed, aided by targeted male smokers' education and oral screening by their dentists and health care providers.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"26 1","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13729621/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149317913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patient-reported oral complaints during cancer treatment: Dietary consequences, supportive care, and self-management in a cross-sectional survey. 在一项横断面调查中,癌症治疗期间患者报告的口腔不适:饮食后果、支持性护理和自我管理。
IF 3.8 2区 医学
BMC Oral Health Pub Date : 2026-11-03 DOI: 10.1186/s12903-026-10389-0
Enno Dosch, Jutta Hübner, Clemens Wolf, Jens Büntzel, Luca Schmidt
{"title":"Patient-reported oral complaints during cancer treatment: Dietary consequences, supportive care, and self-management in a cross-sectional survey.","authors":"Enno Dosch, Jutta Hübner, Clemens Wolf, Jens Büntzel, Luca Schmidt","doi":"10.1186/s12903-026-10389-0","DOIUrl":"10.1186/s12903-026-10389-0","url":null,"abstract":"<p><strong>Background: </strong>Oral complaints are common during cancer treatment and may interfere with eating and perceived quality of life. However, patient-reported evidence addressing dental and gingival complaints, xerostomia, taste alterations, counselling, and self-management remains limited.</p><p><strong>Methods: </strong>We conducted an anonymous cross-sectional survey among adults in Germany with current or previous oncological treatment using paper-based and online questionnaires (January-June 2025). Analyses were based on valid responses for each item and included descriptive statistics, Pearson's chi-square tests, linear-by-linear association tests, 95% confidence intervals for selected key prevalence estimates, and exploratory multivariable logistic regression sensitivity analyses adjusted for age and gender.</p><p><strong>Results: </strong>The survey included 222 patients. New, additional, or worsening dental and gingival complaints during cancer treatment were reported by 41.9% (83/198; 95% CI 35.3-48.9%) of respondents. Xerostomia was reported by 56.6% (120/212; 95% CI 49.9-63.1%) and taste alterations by 68.0% (138/203; 95% CI 61.3-74.0%). Self-reported reduced food intake attributed to dental or gingival complaints was reported by 27.9% (57/204; 95% CI 22.2-34.5%), while 25.0% (46/184; 95% CI 19.3-31.7%) reported perceived quality-of-life impairment attributed to these complaints. In exploratory sensitivity analyses adjusted for age and gender, new, additional, or worsening complaints remained associated with reduced food intake (adjusted OR 7.85, 95% CI 3.70-16.62) and perceived quality-of-life impairment (adjusted OR 15.25, 95% CI 5.81-40.06). Among participants with xerostomia, the proportion reporting reduced food intake increased from 5.1% among those with no xerostomia-related eating difficulty to 91.7% among those with severe difficulty (p < 0.001). Overall, 43.1% (87/202; 95% CI 36.4-50.0%) reported receiving support or counselling regarding oral health.</p><p><strong>Conclusions: </strong>In this recruited sample, oral complaints during cancer treatment were common and were associated with eating-related burden and perceived quality-of-life impairment. These exploratory associations persisted after limited adjustment for age and gender but do not establish causality. Fewer than half of respondents reported receiving oral-health counselling, although perceived helpfulness was high among recipients, suggesting a potential gap in the reach of such support. These findings support prospective evaluation of repeated, function-oriented oral-health assessment and appropriate dental or nutritional referral rather than demonstrating the effectiveness of these approaches.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"26 1","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13733013/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149317912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determinants of extended inpatient care in odontogenic cervicofacial infections: a retrospective observational study. 牙源性颈面感染延长住院治疗的决定因素:一项回顾性观察性研究。
IF 3.8 2区 医学
BMC Oral Health Pub Date : 2026-11-03 DOI: 10.1186/s12903-026-10392-5
Anna Aydin, Lawik Revend, Doha Revend, Thomas Beikler, Manfred Giese, Oliver Schuck, Johannes Schunk, Florian Dudde
{"title":"Determinants of extended inpatient care in odontogenic cervicofacial infections: a retrospective observational study.","authors":"Anna Aydin, Lawik Revend, Doha Revend, Thomas Beikler, Manfred Giese, Oliver Schuck, Johannes Schunk, Florian Dudde","doi":"10.1186/s12903-026-10392-5","DOIUrl":"10.1186/s12903-026-10392-5","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to identify clinical and demographic factors associated with prolonged hospitalisation in patients treated for severe odontogenic cervicofacial infections (CFI).</p><p><strong>Methods: </strong>This retrospective study analysed 152 patients who were treated in an inpatient setting for CFI at the Department of Oral and Maxillofacial Surgery, Army Hospital Hamburg, between January 2022 and December 2023. Patients were stratified based on length of hospital stay (LOS) into two groups: <7 days and ≥ 7 days. Demographic, clinical, laboratory, treatment-related and timing data were compared to determine their association with prolonged LOS.</p><p><strong>Results: </strong>Patients with prolonged hospitalisation (≥ 7 days; n = 79) were older and more frequently had recorded pre-existing disease, multi-space infection, submandibular or floor-of-mouth involvement, dyspnoea, elevated inflammatory markers and delayed presentation in unadjusted analyses. In multivariable logistic regression, recorded pre-existing disease (aOR 6.04, 95% CI 1.10-33.18; p = 0.038) and longer time from symptom onset to hospital presentation (aOR 2.86 per day, 95% CI 2.01-4.07; p < 0.001) remained independently associated with prolonged hospitalisation.</p><p><strong>Conclusions: </strong>Although several demographic, anatomical and clinical factors were associated with prolonged hospitalisation in unadjusted analyses, recorded pre-existing disease and delayed hospital presentation remained independently associated with prolonged LOS after multivariable adjustment. These findings highlight the potential importance of comorbidity and timely presentation in identifying patients at risk of extended inpatient care, but prospective multicentre validation is warranted.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"26 1","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13729297/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149317900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Protocol for the GAPA person-centred dental care at home intervention: a substudy within a cluster randomised controlled trial in Swedish home care. GAPA以人为中心的家庭牙科护理干预方案:瑞典家庭护理集群随机对照试验中的一项子研究。
IF 3.8 2区 医学
BMC Oral Health Pub Date : 2026-11-03 DOI: 10.1186/s12903-026-10340-3
Jessica Persson Kylén, Sara Björns, Anna Adolfsson, Ulrika Lindmark, Catharina Hägglin, Annica Almståhl, Henrik Imberg, Martin Lundegard, Sofia Torstensson, Elisabeth Söder, Kerstin Karlén, Ann-Christine Baar, Sven Persson Kylén, Anna Bogren, Carina Fjällman, Björn Klinge, Helle Wijk
{"title":"Protocol for the GAPA person-centred dental care at home intervention: a substudy within a cluster randomised controlled trial in Swedish home care.","authors":"Jessica Persson Kylén, Sara Björns, Anna Adolfsson, Ulrika Lindmark, Catharina Hägglin, Annica Almståhl, Henrik Imberg, Martin Lundegard, Sofia Torstensson, Elisabeth Söder, Kerstin Karlén, Ann-Christine Baar, Sven Persson Kylén, Anna Bogren, Carina Fjällman, Björn Klinge, Helle Wijk","doi":"10.1186/s12903-026-10340-3","DOIUrl":"10.1186/s12903-026-10340-3","url":null,"abstract":"<p><strong>Background: </strong>Oral health is essential to healthy ageing and closely linked to well-being, social participation, and quality of life. Frail older adults are at high risk of oral diseases, yet oral health is often insufficiently integrated into home care. Care staff frequently report limited competence and unclear routines, while older adults wish to participate actively in decisions about their oral health. GAPA Person-Centered Dental Care @ Home (Dental PCC@Home) is a co-designed model developed with older adults, significant others (informal caregivers), municipal care staff, and dental professionals. This substudy evaluates if Dental PCC@Home will promote oral health, participation, and self-determination among older adults living with complex care needs.</p><p><strong>Methods: </strong>Dental PCC@Home is embedded within the parent GAPA cluster randomised controlled trial. Decisions about dental care are guided by a patient decision aid and discussion of needs expressed by the older adult or identified by care staff. Participation in the substudy is voluntary. Eligible intervention-group participants are offered a patient decision aid to support decisions about whether and how to receive dental care, followed by one of four pathways: online dental consultation, mobile home dental care, a dental clinic visit, or declining dental care. Eligible control-group participants receive standard care. Oral health and quality-of-life assessments are conducted at baseline and at six and twelve months; cognitive function is assessed at baseline only. Co-primary outcomes are changes in oral health status (ROAG) and oral health-related quality of life (GOHAI) from baseline to twelve months. General health-related quality of life (EQ-5D-5 L) is a secondary outcome. Quantitative analyses will account for clustering and repeated measurements. Semi-structured interviews with older adults, significant others, and care staff will explore experiences of care, decision-making, and implementation and will be analysed using qualitative content analysis.</p><p><strong>Discussion: </strong>This project will generate evidence on a new cross-organisational model designed to improve access to oral health care for frail older adults living at home. By integrating dental care into existing care processes and offering flexible care pathways, the model has the potential to strengthen autonomy, reduce inequalities, promote health and, when indicated, address oral diseases earlier in home care. The findings may inform future practice, policy development, and person-centred approaches to oral health in ageing populations.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov NCT06310798. Registered on March 13, 2024.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"26 1","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13733002/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149317914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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