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Prevalence and associated factors of denture use among older adults living in rural and urban areas of China: a national cross-sectional study.
IF 2.6 2区 医学
BMC Oral Health Pub Date : 2025-03-21 DOI: 10.1186/s12903-025-05684-1
Yuxin Eva Lin, Xiaoyue Zhang, Meijun Chen, Ying Ji, Yuhui Shi, Yuting Lin, Xiaochen Yang, Wangnan Cao, Chun Chang
{"title":"Prevalence and associated factors of denture use among older adults living in rural and urban areas of China: a national cross-sectional study.","authors":"Yuxin Eva Lin, Xiaoyue Zhang, Meijun Chen, Ying Ji, Yuhui Shi, Yuting Lin, Xiaochen Yang, Wangnan Cao, Chun Chang","doi":"10.1186/s12903-025-05684-1","DOIUrl":"10.1186/s12903-025-05684-1","url":null,"abstract":"<p><strong>Backgrounds: </strong>Tooth loss, often considered as an inevitable result of ageing, is one of the most frequently stated problems with older adults worldwide, which entails a negative impact on physical and mental health, as well as quality of life. However, there is urban-rural gap among older adults in both oral health condition and dental service utilization. The study focused on the urban-rural gap in Chinese older population, aiming to describe their tooth loss and denture use status, and explore the associated factors, hoping to provide insights into improving the oral healthcare system in China and other developing countries.</p><p><strong>Methods: </strong>This cross-sectional study used data collected from May to September in 2020. A stratified, multi-stage cluster sampling design was used to produce nationally representative samples of 2709 adults aged 60 years and older. The dependent variable was denture use of the participant. Determinants included demographic characteristics, health status, social support, oral health knowledge and health service utilization. Descriptive analysis was conducted to describe the sample characteristics, and Generalized Linear Mixed Model was used to identify independent factors associated with denture use among older adults in rural and urban China respectively.</p><p><strong>Results: </strong>There were significant urban-rural differences in tooth loss, denture use and health service utilization among Chinese older adults. Urban participants' denture use was associated with oral health knowledge (OR = 1.29, 95%CI = 1.07-1.56). Rural participants' denture use was associated with oral health knowledge (OR = 1.23, 95%CI = 1.02-1.47), dental checkup in the last six months (OR = 1.19, 95%CI = 1.00-1.40), and social support (OR = 1.22, 95%CI = 1.03-1.44).</p><p><strong>Conclusions: </strong>Greater efforts should be made to enhance oral health education and emphasize the importance of regular dental checkups among older population. Targeted focus on different aspects of oral health based on the characteristics of different populations is suggested. Policymakers should be aware of the urban-rural disparity in distribution and utilization of oral health services.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"415"},"PeriodicalIF":2.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11927226/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143676698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to: Accuracy of artificial intelligence-based segmentation in maxillofacial structures: a systematic review. 更正:基于人工智能的颌面部结构分割的准确性:系统综述。
IF 2.6 2区 医学
BMC Oral Health Pub Date : 2025-03-21 DOI: 10.1186/s12903-025-05833-6
Manea Alahmari, Maram Alahmari, Abdulmajeed Almuaddi, Hossam Abdelmagyd, Kumuda Rao, Zaid Hamdoon, Mohammed Alsaegh, Nallan C S K Chaitanya, Shishir Shetty
{"title":"Correction to: Accuracy of artificial intelligence-based segmentation in maxillofacial structures: a systematic review.","authors":"Manea Alahmari, Maram Alahmari, Abdulmajeed Almuaddi, Hossam Abdelmagyd, Kumuda Rao, Zaid Hamdoon, Mohammed Alsaegh, Nallan C S K Chaitanya, Shishir Shetty","doi":"10.1186/s12903-025-05833-6","DOIUrl":"10.1186/s12903-025-05833-6","url":null,"abstract":"","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"418"},"PeriodicalIF":2.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11929269/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143676571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of conventional and digital fabrication techniques on marginal and internal fit of lithium disilicate endocrowns.
IF 2.6 2区 医学
BMC Oral Health Pub Date : 2025-03-21 DOI: 10.1186/s12903-025-05775-z
Duygu Ece Keskin, Gaye Sağlam, Şükriye Ece Geduk
{"title":"Effect of conventional and digital fabrication techniques on marginal and internal fit of lithium disilicate endocrowns.","authors":"Duygu Ece Keskin, Gaye Sağlam, Şükriye Ece Geduk","doi":"10.1186/s12903-025-05775-z","DOIUrl":"10.1186/s12903-025-05775-z","url":null,"abstract":"<p><strong>Background: </strong>This study aims to compare the marginal and internal fit of lithium disilicate endocrowns produced by conventional and/or digital impression and fabrication techniques.</p><p><strong>Methods: </strong>Endocrown preparations were performed on 40 mandibular first molars. The teeth were divided into four groups (n = 10) based on the impression and fabrication technique; CON: conventional impression/manuel wax patterns/heat-pressed endocrowns, DCD: digital impression/CAD-CAM milled wax patterns/heat-pressed endocrowns, D3D: digital impression/3D printed resin patterns/heat-pressed endocrowns, DC: digital impression/digital design/CAD-CAM milled endocrowns. The marginal and internal fits of the endocrowns were measured by using the silicon replica technique and stereomicroscope with 57x magnification. The statistical analysis was carried out using the Kruskal-Wallis and paired two-sample t-tests. The significance level was set at p < 0.05.</p><p><strong>Results: </strong>Marginal fit measurements revealed the following; CON: 111 μm, DCD: 96 μm, D3D: 91 μm, and DC: 93 μm. A statistically significant difference was found between the CON group and the other groups in the marginal fit measurement. Internal fit measurements revealed the following; CON: 120.75 μm, DCD: 112 μm, D3D: 114.88 μm, and DC: 122 μm. There was a statistically significant difference between the CON group and the DCD group in the internal fit measurement, while no significant difference observed between the other groups.</p><p><strong>Conclusions: </strong>It is concluded that all endocrowns had a clinically acceptable marginal and internal fit. The use of digitally generated patterns, CAD-CAM milled or 3D printed, in the fabrication of endocrowns can be effective in producing restorations with improved marginal and internal adaptation.</p><p><strong>Clinical relevance: </strong>The use of digital production methods can improve the marginal and internal adaptation of endocrown restorations.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"416"},"PeriodicalIF":2.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11927280/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143676609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Systematic review and meta-analysis of the prevalence of oral cancer in Nigeria.
IF 2.6 2区 医学
BMC Oral Health Pub Date : 2025-03-21 DOI: 10.1186/s12903-025-05724-w
Ucheoma Nwaozuru, Chisom Obiezu-Umeh, Somtochukwu Anthonia Uzodufa, Abideen Salako, Folahanmi Tomiwa Akinsolu, Oliver Chukwujekwu Ezechi, Titilola Gbajabiamila, Francisca Nwaokorie, Omolola Titilayo Alade, George Uchenna Eleje, Joanne Lusher, Morẹ Nikẹ Oluwátóyìn Foláyan
{"title":"Systematic review and meta-analysis of the prevalence of oral cancer in Nigeria.","authors":"Ucheoma Nwaozuru, Chisom Obiezu-Umeh, Somtochukwu Anthonia Uzodufa, Abideen Salako, Folahanmi Tomiwa Akinsolu, Oliver Chukwujekwu Ezechi, Titilola Gbajabiamila, Francisca Nwaokorie, Omolola Titilayo Alade, George Uchenna Eleje, Joanne Lusher, Morẹ Nikẹ Oluwátóyìn Foláyan","doi":"10.1186/s12903-025-05724-w","DOIUrl":"10.1186/s12903-025-05724-w","url":null,"abstract":"<p><strong>Introduction: </strong>Oral cancer is ranked among the ten most common cancers in the world and is a growing public health concern in Nigeria. However, the extent of the burden of oral cancer in Nigeria is poorly understood. A better understanding of the prevalence of oral cancer will inform the development and implementation of efficient and effective oral cancer prevention and management strategies. This systematic review and meta-analysis aimed to estimate the prevalence of oral cancer in Nigeria to guide relevant oral health interventions and policies.</p><p><strong>Methods: </strong>We searched PubMed, Embase, Scopus, Cumulative Index to Nursing and Allied Health Literature (CINAHL), and Web of Science for studies published from 1990 until August 15, 2023. We included cohort, cross-sectional, case-control, descriptive, and interventional studies that reported prevalence data for oral cancer in Nigeria. The primary outcome was the pooled prevalence of oral cancer. Meta-analysis was performed using the random effect model. The Higgins inconsistency index -I<sup>2</sup> index was used to evaluate heterogeneity. The quality of the studies was assessed using the Joanna Briggs Institute Critical Appraisal Checklist.</p><p><strong>Results: </strong>In total, 3025 articles were screened, and data from 7 studies with a total sample size of 9188 (1702 oral cancer cases) were included in the meta-analysis. Participants age ranged from 0 to 100 years. Oral cancer prevalence varied across the studies, ranging from 7.5% to 41%. The pooled prevalence of oral cancer in Nigeria was 20% (95% confidence interval, CI:0.11-0.28, I<sup>2</sup> = 99%, P < 0.0001). An estimate of the total variation between studies revealed substantial heterogeneity (I<sup>2</sup> = 99%). The prevalence rate differed between gender populations, with more predilection to males (11%) than females (7%).</p><p><strong>Conclusions: </strong>The current analysis indicates an overall pooled oral cancer prevalence of 20% in Nigeria. The high burden of oral cancer in Nigeria highlights a need for public health interventions and policies to promote the prevention and early detection of oral cancer. The analysis also shows a higher prevalence of oral cancer among men. Population-based studies are necessary to better understand individual differences in oral cancer.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"414"},"PeriodicalIF":2.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11927334/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143676700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The association of third molars with mandibular incisor crowding in a group of the Yemeni population in Sana'a city: cone-beam computed tomography.
IF 2.6 2区 医学
BMC Oral Health Pub Date : 2025-03-20 DOI: 10.1186/s12903-025-05733-9
Khalid Aldhorae, Ramy Ishaq, Salah Alhaidary, Ashraf Mohammed Alhumaidi, Mohammed M Al Moaleem, Ghamdan Al Harazi, Naela Al-Mogahed, Hani Homaid, Sadam Ahmed Elayah
{"title":"The association of third molars with mandibular incisor crowding in a group of the Yemeni population in Sana'a city: cone-beam computed tomography.","authors":"Khalid Aldhorae, Ramy Ishaq, Salah Alhaidary, Ashraf Mohammed Alhumaidi, Mohammed M Al Moaleem, Ghamdan Al Harazi, Naela Al-Mogahed, Hani Homaid, Sadam Ahmed Elayah","doi":"10.1186/s12903-025-05733-9","DOIUrl":"10.1186/s12903-025-05733-9","url":null,"abstract":"<p><strong>Background: </strong>Multiple factors contribute to mandibular incisor crowding. However, the role of wisdom teeth in these irregularities remains a controversial issue among clinicians. Therefore, this study aimed to determine the potential association between mandibular incisor crowding and the presence or absence of lower wisdom teeth using CBCT image analysis.</p><p><strong>Materials and methods: </strong>A total of 64 CBCT images of adult patients were recruited. These CBCT images were classified into two groups according to the presence or absence of the lower wisdom teeth on the panoramic view. After the classification, the severity of crowding was calculated by utilizing Little's irregularity index. Points such as A point, Nasion, and B point (Supramentale) were identified on the software program. The significance level was set at P < 0.05.</p><p><strong>Results: </strong>There was no statistically significant correlation (P = 0.780) in the crowding of the mandibular incisor among the groups with the presence or absence of the lower wisdom teeth. Group 1 (with wisdom teeth) was 5.85 ± 4.05 mm, classified as a moderate irregularity; similarly, group 2 (without wisdom teeth) showed moderate irregularity with a mean value of 5.32 ± 3.12 mm. There was an incisor crowding with a severe irregularity in 18 patients (28.1%), a minimal irregularity in 15 patients (23.4%), a moderate irregularity in 14 patients (21.9%), a very severe irregularity in 10 patients (15.6%), and a perfect alignment in 7 patients (10.9%).</p><p><strong>Conclusions: </strong>The presence and absence of lower wisdom teeth do not influence the mandibular incisor crowding.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"410"},"PeriodicalIF":2.6,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924849/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143668813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of alloplastic materials, biologics, and their combinations, along with defect characteristics, on short-term intrabony defect surgical treatment outcomes: a systematic review and network meta-analysis.
IF 2.6 2区 医学
BMC Oral Health Pub Date : 2025-03-20 DOI: 10.1186/s12903-025-05782-0
Khanti Rattanpornsompong, Kantapon Rattanaprukskul, Sikharate Prachanukoon, Kanokrat Sriwangyang, Mawika Rinkrathok, Junji Tagami, Thantrira Porntaveetus
{"title":"Influence of alloplastic materials, biologics, and their combinations, along with defect characteristics, on short-term intrabony defect surgical treatment outcomes: a systematic review and network meta-analysis.","authors":"Khanti Rattanpornsompong, Kantapon Rattanaprukskul, Sikharate Prachanukoon, Kanokrat Sriwangyang, Mawika Rinkrathok, Junji Tagami, Thantrira Porntaveetus","doi":"10.1186/s12903-025-05782-0","DOIUrl":"10.1186/s12903-025-05782-0","url":null,"abstract":"<p><strong>Background: </strong>Treating periodontal intrabony defects remains challenging, alloplast materials and biologics are increasingly utilized to improve regeneration outcomes. However, comparative efficacy on alloplast materials remains limited. This study aimed to evaluate the effectiveness of alloplastic materials, both alone and combined with biologics, in treating periodontal defects.</p><p><strong>Methods: </strong>A systematic search of PubMed, Scopus, and CENTRAL identified 74 eligible randomized controlled trials. Meta-analysis assessed data heterogeneity based on defect depth and morphology, classifying defects by wall configuration. Network meta-analysis compared clinical attachment level (CAL) gain, probing depth (PD) reduction, and radiographic linear bone (RLB) gain up to 12 months. Risk of bias was evaluated using the Cochrane Risk of Bias 2 tool, and confidence in network meta-analysis was graded using CINeMA.</p><p><strong>Results: </strong>Defect depth and morphology significantly impacted heterogeneity outcomes at 6 months, but by 12 months, differences across treatments were less significant. Biphasic calcium phosphate (BCP) and nanocrystalline hydroxyapatite (nHA) showed notable improvements in CAL gain, PD reduction, and RLB gain. Combining nHA with platelet-rich fibrin (PRF) outperformed open flap debridement (mean differences at 6 months for CAL gain: 1.37 mm, PD reduction: 1.52 mm and RLB gain: 1.39 mm). SUCRA ranked bioglass and BCP highest for single treatments, while bioglass with platelet-rich plasma and nHA + PRF excelled among combinations.</p><p><strong>Conclusions: </strong>Alloplastic materials, particularly BCP and nHA, significantly enhance periodontal treatment outcomes, especially when combined with biologics like PRF. Defect depth and morphology influence treatment efficacy at 6 months, though by 12 months, treatment outcomes converge, underscoring the value of early, tailored strategies in periodontal therapy.</p><p><strong>Trial registration: </strong>Not applicable.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"413"},"PeriodicalIF":2.6,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11927257/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143668838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does reducing the acid-etching time increase the micro-tensile bond strength of a bulk fill composite to dentin using different universal adhesives?
IF 2.6 2区 医学
BMC Oral Health Pub Date : 2025-03-20 DOI: 10.1186/s12903-025-05602-5
Elif Öztürk, Omer Taha Meric, Dilek Helvacioglu-Yigit
{"title":"Does reducing the acid-etching time increase the micro-tensile bond strength of a bulk fill composite to dentin using different universal adhesives?","authors":"Elif Öztürk, Omer Taha Meric, Dilek Helvacioglu-Yigit","doi":"10.1186/s12903-025-05602-5","DOIUrl":"10.1186/s12903-025-05602-5","url":null,"abstract":"<p><strong>Objectives: </strong>The objective of this in vitro study was to evaluate whether a reduced phosphoric acid etching time would have an impact on the microtensile bond strength (µTBS) of different universal adhesives to dentin using a bulk-fill composite.</p><p><strong>Methods: </strong>Forty-eight freshly extracted non-carious human molars were immersed in acrylic resin and cut to a height of 4 mm from the highest tubercle crest towards the cervical region. Dentin surfaces were subjected to 37% phosphoric acid pretreatment for 0, 3, or 15 s (s), rinsed with water for 20 s and gently dried, and wet-bonded. Two universal adhesives (Single Bond Universal, 3 M-ESPE; Adhese Universal, Ivoclar Vivadent) were used in this study. The Tofflemire matrix was added to each tooth, and a bulk-fill resin composite (Tetric EvoCeram Bulk-Fill, Ivoclar Vivadent) with a thickness of 5 mm was applied. The tooth composite blocks were cured using a light-emitting diode unit for either 20-40 s. Twelve groups were included (four teeth per group). All samples were immersed in distilled water for 24 h at 37°C. The samples were sectioned under water cooling to obtain multiple sticks approximately 1.0 × 1.0 × 8 mm<sup>3</sup> in size using a non-trimming technique with water cooling. The µTBS test was performed (n = 20 sticks for each group). The data were analysed via a Welch analysis of variance (ANOVA) and the Games-Howell post hoc test (SPSS 23.0). The interactions between the three factors were analysed with a three-way ANOVA.</p><p><strong>Results: </strong>Significant differences were observed among the experimental groups (p < 0.05). Both adhesives exhibited the highest bond-strength values in the groups for which acid was applied to the dentin for 3 s and the composite resin was light-cured for 40 s, resulting in statistically significantly higher values for these two groups compared with the other groups (p < 0.05).</p><p><strong>Conclusion: </strong>Reducing the etching time to 3 s compared to the traditional etching time of 15 s increased the micro-tensile bond strength of the bulk-fill composite to dentin using universal adhesives.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"412"},"PeriodicalIF":2.6,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924721/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143668743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characteristics of phase 4 clinical trials on Dental Caries registered at Clinicaltrials.gov.
IF 2.6 2区 医学
BMC Oral Health Pub Date : 2025-03-20 DOI: 10.1186/s12903-025-05662-7
Kerim Safa Kul, Muhammet Kerim Ayar
{"title":"Characteristics of phase 4 clinical trials on Dental Caries registered at Clinicaltrials.gov.","authors":"Kerim Safa Kul, Muhammet Kerim Ayar","doi":"10.1186/s12903-025-05662-7","DOIUrl":"10.1186/s12903-025-05662-7","url":null,"abstract":"<p><strong>Background: </strong>Dental caries, a widespread chronic oral disease, is caused by multiple factors including microorganisms, genetic predisposition. Despite being preventable, it poses a significant global burden. This study reviews all phase 4 clinical trials on dental caries registered at ClinicalTrials.gov to provide a comprehensive overview of their characteristics.</p><p><strong>Methods: </strong>A search was conducted on the ClinicalTrials.gov database using keywords. The registration data for all relevant phase 4 studies concerning 'Dental Caries' were retrieved. This search was conducted on the 23rd of January, 2024.</p><p><strong>Results: </strong>The analysis included 58 phase 4 clinical trials, with most studies (67.2%) reporting complete data. The majority (63.8%) had fewer than 100 participants, and the predominant sponsors were medical institutions (77.6%). Geographically, the highest percentage of studies were conducted in South America (24.1%), with the lowest in North America (10.3%). Interventional trials primarily focused on treatment (51.7%) and prevention (41.4%), with a significant portion being randomized (93.1%). Blinding varied, with single and double blinding each used in 25.9% of studies. Drug interventions were the most common (60.6%), followed by other categories such as dietary supplements and procedures. Among drug interventions, agents containing fluoride were the largest category, accounting for 52.6% of the trials. Fluoride varnishes and silver diamine fluoride were the most frequently evaluated. Sedatives and pain relievers constituted 15.7% of the trials, with midazolam and ketamine being predominant. Other drugs accounted for 23.2% of the trials, featuring diverse substances such as inactivated poliovirus vaccine and xylitol. Dental materials and operative treatments made up 29.5% of the trials, with resin and fissure sealants being the most commonly evaluated.</p><p><strong>Conclusion: </strong>This analysis of phase 4 clinical trials highlighted fluoride as the most studied intervention for dental caries prevention. The analysis also revealed a need for further research on non-fluoride interventions and emphasized the importance of using evidence-based practices in dental care for improved oral health outcomes.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"411"},"PeriodicalIF":2.6,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924847/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143668739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation of dental health and salivary microbiota characteristics of children with visual impairment in Guangzhou, China.
IF 2.6 2区 医学
BMC Oral Health Pub Date : 2025-03-19 DOI: 10.1186/s12903-025-05713-z
Qiong Feng, Wengyan Huang, Xuedan Zhao, Ting Sheng, Bo Peng, Si Meng, Weijia Liu, Lihong Ge, Lijing Wang, Janak Lal Pathak, Qianzhou Jiang, Rong Lin, Sujuan Zeng
{"title":"Investigation of dental health and salivary microbiota characteristics of children with visual impairment in Guangzhou, China.","authors":"Qiong Feng, Wengyan Huang, Xuedan Zhao, Ting Sheng, Bo Peng, Si Meng, Weijia Liu, Lihong Ge, Lijing Wang, Janak Lal Pathak, Qianzhou Jiang, Rong Lin, Sujuan Zeng","doi":"10.1186/s12903-025-05713-z","DOIUrl":"10.1186/s12903-025-05713-z","url":null,"abstract":"<p><strong>Background: </strong>The prevalence of visual impairment (VS) among children in China is increasing. The oral microbiome is crucial for maintaining homeostasis and health. This study aimed to investigate the oral health and hygiene habits of children with VS in Guangzhou and explore the differences in salivary microbiota (SM) between children with VS and healthy vision (HS).</p><p><strong>Method: </strong>This study included oral health examinations and surveys of oral hygiene habits among 101 children with VS. Saliva samples from 20 children with VS and 20 with HS were analysed for oral microbiota. The 16s rRNA V3-V4 regions were sequenced using the Illumina MiSeq platform and operational taxonomic units were clustered using QIIME for statistical analysis.</p><p><strong>Results: </strong>Inadequate oral hygiene was observed among 101 children with VS, aged 6-16, who displayed a high caries rate of 92.1%. There was no significant difference in the overall composition of the salivary microbiota between the two groups. HS group had a higher abundance of Bacillota, Patescibacteria, and Spirochaetota at the phylum level; Bacilli, Negativicutes, and Saccharimonadia at the class level; and Streptococcus at the genus level. In contrast, VS group showed a greater abundance of Actinomycetota, Bacteroidota, Pseudomonadota, and Fusobacteriota (at the phylum level) and Actinomycetia, Bacteroidia, Gammaproteobacteria, Fusobacteriia, and Clostridia (at the class level), along with Rothia, Neisseria, Veillonella, Prevotella_7, Actinomyces, Leptotrichia, and Lactobacillales (at the genus level). Actinomycetota was significantly and positively correlated with gingivitis and dental caries, and Streptococcus salivarius was more abundant in children with VS.</p><p><strong>Conclusion: </strong>This study underscores the importance of improving oral healthcare for schoolchildren with VS in Guangzhou, China and provides valuable insights into the characteristics of the salivary microbiota of this population, identifying potential targets for interventions aimed at enhancing oral health.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"408"},"PeriodicalIF":2.6,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924837/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In vitro assessment of the accuracy of two intra-oral scanners for post space scanning in a fully digital workflow.
IF 2.6 2区 医学
BMC Oral Health Pub Date : 2025-03-19 DOI: 10.1186/s12903-025-05723-x
Mennatallah Wahba, Reham Said ElBasty
{"title":"In vitro assessment of the accuracy of two intra-oral scanners for post space scanning in a fully digital workflow.","authors":"Mennatallah Wahba, Reham Said ElBasty","doi":"10.1186/s12903-025-05723-x","DOIUrl":"10.1186/s12903-025-05723-x","url":null,"abstract":"<p><strong>Background: </strong>With the rapid advancements in computer-aided imaging, the potential for chairside fabrication of custom-made posts utilizing intraoral scanners may offer a reliable alternative to traditional physical impressions. Accordingly, this study aimed to evaluate the accuracy (trueness and precision) of two intra-oral scanners when different post space diameters were employed. Additionally, the scan depth of each intra-oral scanner (IOS) was assessed.</p><p><strong>Methods: </strong>An endodontically treated mandibular canine was inserted in a printed typodont model and prepared with two post-space diameters; a small one (1.5 mm) and a large one (2 mm). Polyvinyl siloxane impressions for the two post-space diameters were taken and then scanned with an extra-oral scanner to serve as reference scans. Each post-space diameter was scanned using CEREC Primescan (n = 8) and Medit i700 (n = 8) intra-oral scanners. Standard tessellation language (STL) files of all intra-oral and extra-oral scans were uploaded to a 3D matching program to evaluate trueness, precision, and post-space length difference. Statistical analysis was performed using different tests for parametric and non-parametric data. The significance level was set at P < 0.05.</p><p><strong>Results: </strong>Regarding the effect of the IOS and the effect of the post-space diameter, both Medit i700 and the small diameter groups using both scanners showed significantly higher root mean square (RMS) values when evaluating trueness. For precision, Medit i700 showed a significantly higher RMS value in the large diameter group. Medit i700 showed a significantly higher difference in post-space length than Primescan in both diameters. Primescan recorded a zero difference in the large diameter group compared to the reference scan.</p><p><strong>Conclusions: </strong>The IOS type and the post-space diameter influenced the scan accuracy and the depth of the scan. Accuracy results were superior when Primescan was implemented for scanning the large diameter post-space subgroup.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"407"},"PeriodicalIF":2.6,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924774/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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