BMC Oral HealthPub Date : 2025-04-26DOI: 10.1186/s12903-025-06033-y
Oğuzhan Yılmaz, Ayşegül Göze Saygın, Giray Bolayır
{"title":"Comparison of fracture resistance of implant-supported fixed prothesis substructure materials with different cross-sectional geometry.","authors":"Oğuzhan Yılmaz, Ayşegül Göze Saygın, Giray Bolayır","doi":"10.1186/s12903-025-06033-y","DOIUrl":"https://doi.org/10.1186/s12903-025-06033-y","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to compare fracture resistance after thermomechanical ageing of prosthetic substructure materials with different connector designs.</p><p><strong>Methods: </strong>Three different prosthetic substructure materials were used in this study: (1) GroupZir: (Zirconia, Fusion ceram, Turkey), (2)GroupPEEK (PEEK, Whitepeaks, CopraPeek, Essen, Germany), (3)GroupFRC (Fibre-reinforced composite, Trinia, Bicon Implant, Rep. of Ireland). A total of 72 implant-supported prosthesis triangular, square, and oval connector designs were created between 2nd premolar and mandibular 2nd molar teeth. After adhesion to the implant abutments with resin cement (Pentron breeze, Kerr), the samples were applied with dynamic loading and thermomechanical ageing (120,000 cycles,120 N,5-55 °C). Fracture resistance values were obtained with a universal test device and SEM images were analysed. The analyses were performed with Two-Way ANOVA and the Tukey test (SPSS 23.00).</p><p><strong>Results: </strong>Both the material and the connector type were found to affect the fracture resistance (F = 8.354, p < 0.05). The highest fracture resistance value was obtained from the triangular shape in GroupZir(3200 ± 91.05) and the lowest from the oval connector design of GroupPEEK material (2410 ± 157.23). Statistically significant differences were determined in the different connector designs of GroupZir(p < 0.05). In the comparisons made according to connector design, a significant difference was obtained between GroupZir and GroupPEEK and between GroupZir and GroupFRC. Deformations were observed in the fracture pattern of the Group Zir samples and deformations in the form of rupture were seen in the GroupPEEK and GroupFRC material samples.</p><p><strong>Conclusions: </strong>The study results demonstrated that the fracture resistance of zirconia, PEEK, and FRC restorations over 3-unit implants with different connectors is affected by connector design. All the materials were seen to be comparable in respect of the forces formed in chewing dynamics.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"645"},"PeriodicalIF":2.6,"publicationDate":"2025-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12034136/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143978859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC Oral HealthPub Date : 2025-04-26DOI: 10.1186/s12903-025-05750-8
Nihan Çelik Uzun, Altuğ Uşun, Davut Çelïk
{"title":"Unveiled stress dynamics: the role of post length and repair materials in perforated tooth models: a finite element analysis study.","authors":"Nihan Çelik Uzun, Altuğ Uşun, Davut Çelïk","doi":"10.1186/s12903-025-05750-8","DOIUrl":"https://doi.org/10.1186/s12903-025-05750-8","url":null,"abstract":"<p><strong>Background: </strong>Post placement is a common practice to reinforce weakened roots. However, the choice of post length and repair material for root perforation influences the stress distribution within the dentin and surrounding tissues. This study aimed to evaluate the effects of post length and repair materials on the stress distribution in perforated tooth models through finite element analysis (FEA).</p><p><strong>Methods: </strong>A three-dimensional FEA model of a mandibular first molar tooth was created via Materialise 3-Matic software. Posts with lengths of 4 mm, 6 mm, and 8 mm inside the root and perforation areas in the middle third of the distal root were created. The control groups (CGs) included nonperforated models (CG4: Control group treated with 4 mm post, CG6: Control group treated with 6 mm post, CG8: Control group treated with 8 mm post) and those with unrepaired (UR) perforations (P) (P4/UR, P6/UR, P8/UR). MTA or Biodentine were used as repair materials for the main analysis groups (P4/MTA, P6/MTA, P8/MTA, P4/Biodentine, P6/Biodentine, P8/Biodentine); subsequently, all the models were restored with a ceramic crown. A 100 N force was applied through opposing teeth, and the maximum von Mises stress values and stress distributions in the model were analyzed.</p><p><strong>Results: </strong>The maximum von Mises stress values in P4/MTA, P6/MTA, P8/MTA, P4/Biodentine, P6/Biodentine, P8/Biodentine models were slightly lower than those in P4/UR, P6/UR, P8/UR models. In the perforated models, extending the post from 6 mm to 8 mm reduced the stresses in the dentin and the post, while increasing the stresses in the perforation area. P8/UR model had the highest stress value at 63.22 MPa, followed by P8/MTA (62.80 MPa) and P8/Biodentine (36.20 MPa), and the lowest stress value was in P6/Biodentine (15.92 MPa) in the perforation area. The lowest stress accumulation was observed in P8/Biodentine (0.036 MPa) model in the PDL.</p><p><strong>Conclusions: </strong>In perforated models, although the overall stresses in the dentine reduced with longer posts, the stresses in the perforation area increased. Biodentine enhances the mechanical stability of tooth structures and reduces stress concentrations, making it a suitable material for managing perforated teeth in post-endodontic restorations.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"646"},"PeriodicalIF":2.6,"publicationDate":"2025-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12034145/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143969338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC Oral HealthPub Date : 2025-04-25DOI: 10.1186/s12903-025-05836-3
Mohammed B A Sarhan, Rika Fujiya, Junko Kiriya, Akira Shibanuma, Rita Giacaman, Masamine Jimba
{"title":"Health literacy mediating the association between health information sources and oral health knowledge among Palestinian adolescent refugees: a cross-sectional study.","authors":"Mohammed B A Sarhan, Rika Fujiya, Junko Kiriya, Akira Shibanuma, Rita Giacaman, Masamine Jimba","doi":"10.1186/s12903-025-05836-3","DOIUrl":"https://doi.org/10.1186/s12903-025-05836-3","url":null,"abstract":"<p><strong>Background: </strong>Oral health diseases pose a major global and public health problem. Access to trusted sources of information might be pivotal for improving health knowledge levels. Health knowledge can be considered a consequence of having or lacking the appropriate health literacy skills. This study identified the association between the number of health information sources and oral health knowledge (OHK) mediated by health literacy.</p><p><strong>Methods: </strong>This cross-sectional household survey targeted Palestinian adolescent refugees in Ramallah and Al-Bireh District of the West Bank, Palestine. We measured OHK using seven questions about basic oral and dental health information. We used the Arabic Health Literacy Assessment Scale for Adolescents to measure health literacy levels. We also asked the adolescents to report their sources of health information. We conducted a mediation analysis using Process Macro for SPSS.</p><p><strong>Results: </strong>This study included 300 adolescents who live in Ramallah and Al Bireh refugee camps. Among family members, adolescents mainly consulted their parents for health information, with 86.3% seeking health information from their mothers and 66.3% from their fathers. Out of seven questions, the mean number of correct answers for the OHK scale was 5.7 (Standard Deviation [SD]1.0). The association between the number of health information sources and OHK was fully mediated by communication health literacy (significant indirect effect: 0.0203, 95% Confidence Interval [CI]: 0.007 to 0.037, and insignificant direct effect β = 0.0267, p = 0.15). This association was partially mediated by functional health literacy (significant indirect effect: -0.008, 95%CI: -0.0173 to -0.0018, and significant direct effect β = 0.0536, p = 0.003).</p><p><strong>Conclusion: </strong>Different types of health literacy can mediate the association between the number of health information sources and OHK. Functional health literacy is necessary to gain knowledge from multiple sources, but it is insufficient. High communication health literacy fully mediated this association. Strengthening communication skills in the context of health would be highly required to effectively transform accessed information into gained knowledge.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"636"},"PeriodicalIF":2.6,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12023511/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143963800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of the effects of using an interdental brush dipped in 0.2% hyaluronic acid gel on clinical periodontal parameters among patients with periodontitis: a randomized controlled trial.","authors":"Özlem Saraç Atagün, Seval Ceylan Şen, Gülbahar Ustaoğlu, Erkan Özcan","doi":"10.1186/s12903-025-06038-7","DOIUrl":"https://doi.org/10.1186/s12903-025-06038-7","url":null,"abstract":"<p><strong>Background: </strong>The additional use of agents with antibacterial and anti-inflammatory activities, such as hyaluronic acid in treating periodontal disease, has recently become popular. This study aimed to evaluate the effects of using an interdental brush dipped in 0.2% HA gel on clinical periodontal parameters.</p><p><strong>Methods: </strong>This randomized controlled trial was conducted among 60 patients with stages II/III grades A/B periodontitis. After full-mouth scaling root planning and oral hygiene training, the patients were divided into two groups; the test group was asked to use an interdental brush dipped in 0.2% HA, while the control group was asked to use a regular interdental brush. Clinical periodontal parameters [ gingival index (GI), plaque index (PI), papillary bleeding index (PBI), pocket depth (PD), and clinical attachment loss (CAL) ] were assessed at baseline and in the 1st and 3rd months after treatment.</p><p><strong>Results: </strong>Clinical periodontal parameters were improved in control and test groups at the 1 and 3-month compared to baseline (p < 0.05). The 1st- and 3rd-month PBIs were significantly lower in the test group (p < 0.05). There was no significant difference between the test and control groups regarding PI, PD, GI, and CAL between the follow-up times.</p><p><strong>Conclusions: </strong>Although the clinical efficacy of the tested methods of interdental brush use was similar, it can be concluded that the use of an interdental brush dipped in HA may contribute to the reduction of gingival bleeding in the early period.</p><p><strong>Clinical significance: </strong>Incorporating HA into the oral hygiene regime after periodontitis treatment using an interdental brush is a useful and practical method. NAME OF THE REGISTRY: https://clinicaltrials.gov/ TRIAL REGISTRATION NUMBER: NCT06309797.</p><p><strong>Date of registration: </strong>07/03/2024 \"Retrospectively registered\". URL: https://clinicaltrials.gov/study/NCT06309797.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"635"},"PeriodicalIF":2.6,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12023370/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143973735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC Oral HealthPub Date : 2025-04-25DOI: 10.1186/s12903-025-06026-x
Zhiwei Tian, Zhongqi Zhao, Marco Aoqi Rausch, Christian Behm, Dino Tur, Hassan Ali Shokoohi-Tabrizi, Oleh Andrukhov, Xiaohui Rausch-Fan
{"title":"A comparative study of the epithelial regeneration capacities of two biomaterials in vitro.","authors":"Zhiwei Tian, Zhongqi Zhao, Marco Aoqi Rausch, Christian Behm, Dino Tur, Hassan Ali Shokoohi-Tabrizi, Oleh Andrukhov, Xiaohui Rausch-Fan","doi":"10.1186/s12903-025-06026-x","DOIUrl":"https://doi.org/10.1186/s12903-025-06026-x","url":null,"abstract":"<p><strong>Background: </strong>Regeneration of periodontal epithelium remains a major focus in current dental research, with various exogenous substitute materials being applied in clinical practice. Yet, the highly organized structure of native tissue still poses considerable challenges for biomaterials attempting to mimic the original environment. In this study, we investigated the effects of a newly developed gelatin/polycaprolactone nanofiber (GPF) and a micro-scaled collagen matrix (CM) on the biological behavior of oral epithelial Ca9-22 cells, aiming to assess the clinical applicability of the materials and conducted a preliminary exploration of the interplay between the Ca9-22 cells and the material properties.</p><p><strong>Methods: </strong>The oral epithelial Ca9-22 cell line was cultured onto the GPF, CM, and tissue culture plate (TCP) for 3, 7, and 14 days. Cell morphology, attachment proliferation/viability, the gene expression of keratin 14 (KRT14), keratin 10 (KRT10), integrin β-1 (ITGB-1), intercellular adhesion molecule 1 (ICAM-1), interleukin 8 (IL-8) and interleukin 1β (IL-1β), the levels of IL-8 proteins were evaluated.</p><p><strong>Results: </strong>Ca9-22 cells exhibited distinct adhesion morphology and distribution patterns on two biomaterials. After 3 days of culturing on GPF, Ca9-22 cells demonstrated higher levels of proliferation/viability compared to those on CM. In most situations, except KRT10, both materials effectively stimulated gene and protein expression related to epithelial regeneration and wound healing, especially in the early stage of culture. Compared to CM, GPF demonstrated a stronger stimulation of KRT14 expression at day 3 and a more significant enhancement of KRT10 expression after 7 and 14 days. However, it was less effective at promoting IL-8 expression after 3 days than the former. The gene expression of KRT10 was suppressed by CM at day 7. The IL-8 protein production was the highest in cells grown on CM.</p><p><strong>Conclusion: </strong>The morphology and cellular functions of oral epithelial cells differed between GPF and CM. Both materials are capable of promoting epithelial regeneration; however, GPF is more conducive to functional stratification of newly formed epithelium, while CM holds a more sustained effect on epithelial proliferation.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"640"},"PeriodicalIF":2.6,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12023557/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143969813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC Oral HealthPub Date : 2025-04-25DOI: 10.1186/s12903-025-06016-z
Arzu Beklen, Muhammet Burak Yavuz, Deniz Uckan
{"title":"Interleukin-37 reduces lipopolysaccharide induced matrix metalloproteinase-9 in gingival epithelial cells.","authors":"Arzu Beklen, Muhammet Burak Yavuz, Deniz Uckan","doi":"10.1186/s12903-025-06016-z","DOIUrl":"https://doi.org/10.1186/s12903-025-06016-z","url":null,"abstract":"<p><strong>Background: </strong>In periodontal diseases, the recognition of pathogen-associated molecular patterns (PAMPs) triggers signaling cascades that lead to the release of matrix metalloproteinases (MMPs). Interleukin-37 (IL-37) is recognized as a key suppressor of the immune response. This study aimed to detect the expression and distribution of IL-37 in gingival tissues and analyze its suppressor role in MMP-9 in response to lipopolysaccharide (LPS)-stimulated gingival epithelial cells.</p><p><strong>Methods: </strong>Immunohistochemistry localized IL-37 in gingival tissues from periodontitis patients and healthy controls (N = 10). The induction of IL-37 expression by LPS was analyzed using the conditioned medium of gingival epithelial cells through enzyme-linked immunosorbent assay (ELISA). To determine the relevant MMP-9 levels in epithelial cells following exposure to LPS alone or in combination with IL-37, both quantitative PCR (qPCR) and enzyme-linked immunosorbent assay (ELISA) were performed.</p><p><strong>Results: </strong>Cultured epithelial cells secreted significantly higher levels of IL-37 when stimulated with LPS compared to unstimulated controls. Both ELISA and qPCR showed that LPS stimulation significantly increased MMP-9 levels. However, co-culture with IL-37 markedly reduced LPS-induced MMP-9 expression at both the protein and mRNA levels. Furthermore, immunohistochemistry revealed increased IL-37 expression in periodontitis tissues, both in epithelial cells and connective tissue.</p><p><strong>Conclusions: </strong>Gingival epithelial cells may contribute to tissue responses in periodontitis through the secretion of MMP-9 in response to PAMPs. Furthermore, IL-37 appears to have a potential role in modulating and reducing this response, as observed in the decreased MMP-9 expression following IL-37 co-stimulation.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"637"},"PeriodicalIF":2.6,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12023668/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143965453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC Oral HealthPub Date : 2025-04-25DOI: 10.1186/s12903-025-05943-1
Zinab Hijazi, Abubaker Qutieshat, Chibuzo Nlemorisa, Abdurahman Salem
{"title":"Recycled PMMA particles from milled discs in denture base materials for improved sustainability.","authors":"Zinab Hijazi, Abubaker Qutieshat, Chibuzo Nlemorisa, Abdurahman Salem","doi":"10.1186/s12903-025-05943-1","DOIUrl":"https://doi.org/10.1186/s12903-025-05943-1","url":null,"abstract":"<p><strong>Objectives: </strong>Recycling polymethyl methacrylate (PMMA) in dentistry offers a sustainable solution to address the environmental challenges posed by material waste. This study evaluates the feasibility of incorporating recycled (PMMA) particles into heat-cured denture base materials, focusing on the effects of particle size and concentration on flexural strength, surface hardness, and surface roughness.</p><p><strong>Material and methods: </strong>Recycled PMMA particles, sourced from milling residuals, were classified into fine (< 400 μm) and whole particles and incorporated into virgin PMMA at 10% and 20% weight/weight (w/w) concentrations to form five groups: Control (100% virgin PMMA), Fine 10% (90% virgin PMMA + 10% fine particles), Fine 20% (80% virgin PMMA + 20% fine particles), Whole 10% (90% virgin PMMA + 10% whole particles), and Whole 20% (80% virgin PMMA + 20% whole particles). Flexural strength (n = 10) was evaluated using a three-point bending test, surface hardness (n = 10) was assessed using the Vickers hardness test (VHN), and surface roughness (n = 10) was measured using an optical profilometer. Statistical analysis was performed using two-way ANOVA and Tukey's post hoc test, with p < 0.05 considered statistically significant.</p><p><strong>Results: </strong>The results showed that fine particle groups (10% and 20%) maintained flexural strength comparable to the control, whereas whole particle groups exhibited significantly lower values (p < 0.05). Surface hardness improved in fine particle groups, with the highest value in the 20% fine particle group, whereas whole particles, particularly at 20%, resulted in the lowest hardness (p < 0.05). Surface roughness remained unaffected across all groups, with values staying within clinically acceptable limits (Ra < 0.2 μm).</p><p><strong>Conclusions: </strong>These findings suggest that fine recycled PMMA particles can be effectively integrated into denture base materials to maintain or improve specific properties while contributing to sustainability.</p><p><strong>Clinical relevance: </strong>This study underscores the potential of recycled PMMA as an environmentally friendly alternative, aligning with global sustainability goals in dental material development.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"639"},"PeriodicalIF":2.6,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12023541/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143979258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC Oral HealthPub Date : 2025-04-25DOI: 10.1186/s12903-025-05940-4
Khaled Ahmed Ibrahim Awad, Mohamed Abdel-Monem Tawik, Mohamed Mohamed Hussein, Shaimaa Ahmed Abo El-Farag, Sally El Sayed Abdel Sameaa
{"title":"Tooth shell versus bone shell technique for horizontal maxillary alveolar ridge augmentation.","authors":"Khaled Ahmed Ibrahim Awad, Mohamed Abdel-Monem Tawik, Mohamed Mohamed Hussein, Shaimaa Ahmed Abo El-Farag, Sally El Sayed Abdel Sameaa","doi":"10.1186/s12903-025-05940-4","DOIUrl":"https://doi.org/10.1186/s12903-025-05940-4","url":null,"abstract":"<p><strong>Background: </strong>This study was designed to evaluate the clinical and radiographical outcome of tooth shell for maxillary alveolar ridge augmentation as an alternative to traditional autogenous bone shell graft.</p><p><strong>Materials and methods: </strong>Twenty eight patients with one or two maxillary extracted teeth (esthetic zone) in need for horizontal bone augmentation were divided into two groups (14 patients each). Group I (control group): bone augmentation was done by using bone shell technique (BST). Group II (study group): bone augmentation was done by using tooth shell technique (TST). Implant stability was evaluated at the time of implant placement, after 4 months (loading time), and 4 months after loading. Radiographic evaluation was made using Cone beam computed tomography (CBCT) scans before grafting (T0), immediately (T1), and 6 months post grafting (T2).</p><p><strong>Results: </strong>In this study, 30 implants were inserted in the esthetic zone. All implants were successfully osseointegrated. No statistically significant difference was found between the studied groups as regards implant stability (P > 0.05) assessed baseline, 4 months after implant placement, and 4 months after loading. The radiographic evaluation demonstrated a statistically significant lower median amount of graft resorption at 1 mm, 5 mm, and 10 mm & total among the study than the control group (p = 0.001, 0.001, 0.04 & 0.001 respectively).</p><p><strong>Conclusion: </strong>TST used for lateral ridge augmentation has excellent dimensional stability and the least amount of graft resorption.</p><p><strong>Trial registration: </strong>This study was retrospectively registered on www.</p><p><strong>Clinicaltrials: </strong>gov with registration number (NCT06416605) on 16 /5 /2024.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"642"},"PeriodicalIF":2.6,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12032675/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143953991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC Oral HealthPub Date : 2025-04-25DOI: 10.1186/s12903-025-06034-x
Ömer Faruk Kaygisiz, Mehmet Turhan Teke
{"title":"Can deepseek and ChatGPT be used in the diagnosis of oral pathologies?","authors":"Ömer Faruk Kaygisiz, Mehmet Turhan Teke","doi":"10.1186/s12903-025-06034-x","DOIUrl":"https://doi.org/10.1186/s12903-025-06034-x","url":null,"abstract":"<p><strong>Objective: </strong>Artificial intelligence (AI) has been widely used in various medical fields to support diagnostic development. The development of different AI techniques has made important contributions to early diagnoses. This research compares and evaluates the diagnostic accuracy of ChatGPT-4o and Deepseek-v3 AI applications in 16 clinical case scenarios in oral pathologies.</p><p><strong>Methodology: </strong>Clinical case scenarios of 16 imaginary oral pathologies were prepared by the authors. The cases were asked to provide 3 possible preliminary diagnoses to two different AI applications, DeepSeek-V3 and ChatGPT-4o, and to reference the literature for these diagnoses. The diagnoses of both AI applications were evaluated with Likert scale by 20 different specialists from two different specialties.</p><p><strong>Results: </strong>The mean score for DeepSeek-v3 was 4.02 ± 0.36. For ChatGPT-4o it was 3.15 ± 0.41. According to the average scores, both models performed at a moderate to high level. Also, between the two AI models. DeepSeek-v3 was statistically better in 9 out of 16 clinical scenarios, while ChatGPT-4o was statistically better in 1 question. In general, DeepSeek-v3 was statistically more successful in the comparison of the two models (p = 0.024). In terms of references, ChatGPT-4o showed 62 references and 50 of them were fake, while 8 out of 48 references were fake in DeepSeek-v3.</p><p><strong>Conclusions: </strong>Chatbot applications have the potential to become a valuable consultant for clinicians in the future thanks to its fast-processing ability. It is clear that it can help healthcare services by reducing the workload of clinicians. It can be said that the Deepseek-v3 model produces better results compared to ChatGPT-4o, but both applications need to be improved for routine use. It is thought that the release of versions of AI models that can only perform scans in the medical field and respond to clinicians by providing more reliable resources may make these models more valuable.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"638"},"PeriodicalIF":2.6,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12023442/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143961940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effect of storage conditions and duration on dimensional stability of 3D-printed endoguides.","authors":"Yunus Emre Ozden, Idil Ozden, Zeynep Ozkurt Kayahan, Ender Kazazoglu","doi":"10.1186/s12903-025-06008-z","DOIUrl":"https://doi.org/10.1186/s12903-025-06008-z","url":null,"abstract":"<p><strong>Background: </strong>This study evaluated the dimensional stability and angular deviations of 3D-printed endodontic guides under varying storage conditions (wet vs. dry, dark vs. daylight) and durations (7 vs. 14 days).</p><p><strong>Methods: </strong>Endodontic guides for the localization of obliterated canals were designed using BlueSkyPlan software (BlueSky Bio, IL, USA) and printed with Biomed Clear Resin V2 (Formlabs Inc., Somerville, USA) via SLA technology. A total of 40 endodontic guides were fabricated and divided into four groups (n = 10), each subjected to either light or dark storage conditions for durations of 7 or 14 days. Dimensional stability was assessed using root mean square (RMS) and angular deviations in Geomagic Design X (Oqton, USA). Statistical analyses were performed using IBM SPSS v29 with independent samples and paired t-tests (p = 0.05).</p><p><strong>Results: </strong>Guides stored in dry conditions had lower RMS (0.052 ± 0.013) and angular deviations (0.29 ± 0.11) than wet conditions (RMS: 0.069 ± 0.028, p = 0.001; angle: 0.36 ± 0.11, p = 0.008). Angular deviations increased at 14 days (p = 0.003). Daylight exposure increased RMS deviations at 14 days in dry conditions (p = 0.001). Wet storage in dark conditions led to greater deviations at both time intervals(p < 0.05).</p><p><strong>Conclusions: </strong>Storage conditions and duration significantly affect the dimensional stability of 3D-printed endodontic guides. Wet storage and prolonged duration reduce accuracy. To maintain precision, guides should be used within 7 days and stored in dry, dark environments.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"641"},"PeriodicalIF":2.6,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12032804/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143972352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}