BMC Oral Health最新文献

{"title":"Needs assessment for interprofessional education module on prevention and early detection of oral cancer among dental interns: a cross- sectional survey.","authors":"Nanditha Sujir, Junaid Ahmed, Anand Ramakrishna, Ciraj Ali Mohammed, Bhaskaran Unnikrishnan, John Hv Gilbert","doi":"10.1186/s12903-024-05123-7","DOIUrl":"10.1186/s12903-024-05123-7","url":null,"abstract":"<p><strong>Background: </strong>The challenges associated with ensuring widespread system changes to enable early diagnosis and prevention of oral cancer could benefit from interprofessional practice. A needs assessment study was conducted to inform the Interprofessional Education and Collaborative Practice (IPECP) course related to oral cancer. The primary objectives of this study were 1) to establish a tool assess the knowledge attitude and practice (KAP) related to prevention and early detection of oral cancer of health professional students, and 2) to assess the same KAP of pre-licensure dental students. Additional objectives were to consider the possibility that dental students would demonstrate good scores related to early detection and prevention of oral cancer thus indicating their readiness for interprofessional learning and collaborative practice.</p><p><strong>Methods: </strong>Two questionnaires were utilized for this study which included 1) Readiness for interprofessional learning was assessed using the pre- validated tool of Readiness for Interprofessional Learning Scale (RIPLS) 2) A questionnaire to assess the KAP related to early diagnosis and prevention of oral cancer which was developed, validated, and evaluated. Statistical analysis includes, descriptive statistics, Mann-Whitney U test, Ordered logistic regression and Probit analysis. p value was set at < 0.05.</p><p><strong>Results: </strong>A total of 130 dental students (74.6% female) were included in the study. Mean scores related to KAP were 15.96 ± 1.394, 4.70 + 1.146, 7.02 ± 1.019 respectively. The mean score of RIPLS was 73.15 ± 15.961. The probability of overall samples to have good RIPLS scores was around 0.68 to 0.76 (Male 0.68-0.82 & Female 0.68 -0.74). The percentage of students having good knowledge score was 93.8%, good attitude score was around 54.6% and good practice score was around 90%.</p><p><strong>Conclusion: </strong>Knowledge and practice related to prevention and early detection of oral cancer were scored highly. Attitude scores were lower in a relatively higher proportion of participants and needed to be addressed in the curriculum. RIPLS score indicates a positive attitude towards interprofessional learning.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"24 1","pages":"1351"},"PeriodicalIF":2.6,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11544993/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142602944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between serum antibodies to oral microorganisms and nonalcoholic fatty liver disease in adults.","authors":"Li Tan, Si-Qun Xu","doi":"10.1186/s12903-024-05141-5","DOIUrl":"10.1186/s12903-024-05141-5","url":null,"abstract":"<p><strong>Background: </strong>Alterations in the bacteria, such as the periodontal bacteria, might be considered potential risk factors for nonalcoholic fatty liver disease (NAFLD). Most studies analyzing this association have focused mainly on a specific periodontal bacteria (Porphyromonas gingivalis) and have involved relatively small study populations (tens or hundreds of individuals). To address this gap, a sizable, nationally representative adult population was utilized to investigate the association between the incidence of NAFLD and high serum IgG antibodies for 19 periodontal bacteria.</p><p><strong>Methods: </strong>To explore this association, data from the Third National Health and Nutrition Examination Survey (NHANES III)-which provides a cross-sectional representation of the noninstitutionalized U.S. population, encompassing 33,994 individuals-were analyzed. Participants aged 40 years and above with data on NAFLD-determined by the gold standard of ultrasound examination (USON)-as well as comprehensive records of serum IgG antibodies against periodontal bacteria, were included, resulting in a final analysis subset of 6,330 individuals.</p><p><strong>Results: </strong>Using a cluster analysis based on the Socransky classification scheme for oral microorganisms, antibody titers for the 19 bacteria were grouped into four clusters-Red-Green, Orange-Blue, Yellow-Orange, and Orange-Red. When these clusters, as well as individual antibody relationships with NAFLD, were examined, the adjusted odds ratios (ORs) ranged from 0.958 [95% confidence interval (CI): 0.916, 1.003] to 1.021 [95% CI: 0.987, 1.055]. This indicated that no statistically significant associations were found (P > 0.05), underscoring the absence of a meaningful link.</p><p><strong>Conclusions: </strong>In summary, it was discovered that there is currently no evidence to correlate serum antibodies to periodontal pathogens with NAFLD in the nationally representative NHANES III.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"24 1","pages":"1352"},"PeriodicalIF":2.6,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11546497/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142602810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between cardiometabolic index (CMI) and periodontitis in US adults: analysis of NHANES data (2009-2014).","authors":"Xingtao Chang, Jukun Song, Xue Du, Jiangling Sun, Xianrun Chen, Jiqin Zhang, Yi Luo, Guohui Bai","doi":"10.1186/s12903-024-05119-3","DOIUrl":"10.1186/s12903-024-05119-3","url":null,"abstract":"<p><strong>Background: </strong>The cardiometabolic index (CMI) is a new predictor of obesity-related diseases, but its link to periodontitis is under-researched. This study aims to examine the potential association between the CMI and periodontitis.</p><p><strong>Methods: </strong>We conducted a cross-sectional study using the National Health and Nutrition Examination Survey (NHANES) database (2009-2014) to examine the potential association between CMI and periodontitis. The study utilized a weighted multivariate logistic model to assess the association between TG, HDL-C, TG/HDL-C, obesity indices (BMI, WC, WHtR, CMI), and periodontitis, employing the area under the receiver operating characteristic curves (ROC) to estimate areas under the curve (AUC). Furthermore, generalized smooth curve fitting was conducted to examine the relationship between CMI and periodontitis. Finally, the study incorporated subgroup analysis and interaction tests to examine consistency across different populations.</p><p><strong>Results: </strong>TG/HDL-C, WHtR, and CMI were positively associated with periodontitis in the fully adjusted classification model. It was observed that for each unit increase in CMI, there was a corresponding 17.8% increase in the prevalence of periodontitis [1.178 (1.049, 1.322) 0.00562] and 18.7% increase in the prevalence of moderate/severe [1.187 (1.057, 1.334) 0.00376] in the fully adjusted model. When CMI was used as a categorical variable, the adjusted OR for periodontitis prevalence increased significantly with increasing CMI after adjusting for all potential covariates (T3 vs. T1: OR, 1.28 [1.06, 1.55], p < 0.05). The ROC analysis indicated that a larger area under the curve was found in the CMI [0.554 (0.538-0.570)] than in the WC [0.544 (0.528-0.560)] and WHtR [0.544 (0.528-0.561)]. Nonetheless, the discrepancy observed did not reach statistical significance (all p > 0.05). Further generalized smooth curve fitting and threshold effect models indicated a positive linear correlation between CMI and periodontitis. Moreover, there is no interactive association between TG/HDL-C, WHtR, CMI, and periodontitis.</p><p><strong>Conclusions: </strong>This cross-sectional study revealed a positive relationship between CMI and periodontitis. Further prospective studies are warranted to validate our findings.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"24 1","pages":"1346"},"PeriodicalIF":2.6,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11539322/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142589949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic effects of acyclovir and acyclovir-clobetasol nanofibers vs. cream formulation for recurrent herpes labialis.","authors":"Shahla Mirzaei, Zahra Golestan Nejad, Faezeh Khozaimeh, Solmaz Mohammadi, Alireza Loqmani","doi":"10.1186/s12903-024-04948-6","DOIUrl":"10.1186/s12903-024-04948-6","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to compare the therapeutic effects of acyclovir nanofiber and acyclovir-clobetasol nanofiber formulations with their non-nano formulations (cream formulation) on recurrent labial herpes.</p><p><strong>Materials and methods: </strong>Eighty patients with labial herpes lesions were divided into four groups, each receiving one of the following treatments: acyclovir-clobetasol nano patch, acyclovir-clobetasol cream, acyclovir nano patch, or acyclovir cream. Pain levels and recovery times were assessed. The Wilcoxon test compared pain levels, while the log-rank test compared healing and scabbing times.</p><p><strong>Results: </strong>Acyclovir-clobetasol nanofiber and cream, along with acyclovir nanofiber, significantly reduced symptoms compared to the acyclovir cream. The recovery and scabbing times were shorter in patients who received acyclovir-clobetasol formulations compared to those receiving acyclovir alone.</p><p><strong>Conclusion: </strong>Acyclovir-clobetasol combinations accelerated recovery times compared to acyclovir alone. Additionally, nanofiber formulations demonstrated enhanced healing efficacy over cream formulations.</p><p><strong>Trial registration: </strong>This trial was retrospectively registered by Iranian Registry of Clinical Trials (IRCT) at 14/11/2023.</p><p><strong>Trial registration number: </strong>IRCT20230926059521N1.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"24 1","pages":"1348"},"PeriodicalIF":2.6,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11539845/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142590045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three-dimensional finite element analysis of occlusal stress on maxillary first molars with different marginal morphologies restored with occlusal veneers.","authors":"Qing Chen, Siyang Luo, Yujuan Wang, Zhu Chen, Ying Li, Maohua Meng, Yamei Li, Nan Xiao, Qiang Dong","doi":"10.1186/s12903-024-05121-9","DOIUrl":"10.1186/s12903-024-05121-9","url":null,"abstract":"<p><strong>Background: </strong>There are differences in the research results regarding which edge design of occlusal veneers can achieve the best long-term success rate as a relatively new fixed prosthesis restoration method. Further research is needed. The three-dimensional finite element method was used to conduct stress analysis on occlusal veneers of maxillary first permanent molars with different thicknesses and margin preparation designs. The aim of this study was to provide mechanical research evidence and a reference for exploring standardized clinical protocols for the design of occlusal veneer restorations of maxillary first molars.</p><p><strong>Method: </strong>A 3Shape (Intraoral Scanner) was used to scan the maxillary first molar teeth in vitro, after which 3D printing was carried out. Three different edge designs were applied to identical teeth: straight-beveled finishing line(SFL), chamfer finishing line(CFL), and standard cuspal inclination(SCI). Preparation was carried out with a thickness of 0.5 mm. Using the surface deformation feature, the occlusal veneer was thickened to 0.5 mm and 1.0 mm, and periodontal ligaments were added. They were then placed into the upper and lower jaws and dental arches. Finite element analysis was performed after applying bite force dispersion to the loading area on the mandible following dynamic contact.</p><p><strong>Results: </strong>(1) As the thickness increased, the maximum Von Mises stress in the occlusal veneers SFL and CFL also increased, while the SCI exhibited the opposite trend. (2). The trend of the maximum Von Mises stress in the adhesive layer decrease gradually with increasing thickness of the occlusal veneer. The stresses of the SFL and CFL is concentrated primarily at the edge position below the functional cusp, resulting in relatively low adhesive stress. However, in the SCI group, the maximum stress at the edge of the adhesive layer exceeds the maximum shear strength of commonly used adhesives.</p><p><strong>Conclusions: </strong>Under the experimental conditions, the mechanical properties of the maximum Von Mises stress in the SFL, CFL, and SCI occlusal veneers meet clinical needs. Incorporating the minimally invasive concept of tooth preservation, a thickness of 1.0 mm are optimal for glass ceramic occlusal veneers on maxillary first molars.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"24 1","pages":"1349"},"PeriodicalIF":2.6,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11542308/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142590059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Er: YAG laser therapy in non-surgical periodontal treatment: an umbrella review.","authors":"Khalid Gufran, Abdullah Saad Alqahtani, Mohammed Alasqah, Abdulaziz Alsakr, Hassan Alkharaan, Hanadi Ghurmallah Alzahrani, Abdullah Almutairi","doi":"10.1186/s12903-024-05120-w","DOIUrl":"10.1186/s12903-024-05120-w","url":null,"abstract":"<p><strong>Aim: </strong>The current umbrella review aimed to summarize the effect of erbium-doped yttrium aluminum garnet (Er: YAG) laser adjunct with the conventional non-surgical periodontal treatment which was evidenced from available systematic reviews.</p><p><strong>Methods: </strong>An extensive literature search was piloted by two independent reviewers in the PubMed, Scopus, Science Direct, and Google Scholar databases. The search was limited to the English language from 2011 to 2023 years. The methodological quality of systematic reviews 2 (AMSTAR 2) guideline was followed to evaluate the risk of bias for the selected studies. Cohen's kappa statistic was implemented to evaluate the level of agreement to assess the risk of bias in the selected studies.</p><p><strong>Results: </strong>A total of 472 studies were initially identified. After removing the duplicates and screening, a total of four studies were selected for the current overview. Based on the quality assessment tool, each study scored as high, moderate, low, and critically low-quality study following AMSTAR 2 tool. Inter-rater reliability by Cohen's Kappa statistics showed near-perfect agreement (0.95) between the two reviewers.</p><p><strong>Conclusion: </strong>Even though weak evidence of effectiveness was observed for Er: YAG laser application in non-surgical periodontal treatment, the clinical benefits are still lacking.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"24 1","pages":"1347"},"PeriodicalIF":2.6,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11566196/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142643450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antimicrobial efficacy and bonding properties of orthodontic bonding systems enhanced with silver nanoparticles: a systematic review with meta-analysis.","authors":"Magdalena Sycińska-Dziarnowska, Liliana Szyszka-Sommerfeld, Magdalena Ziąbka, Gianrico Spagnuolo, Krzysztof Woźniak","doi":"10.1186/s12903-024-05127-3","DOIUrl":"10.1186/s12903-024-05127-3","url":null,"abstract":"<p><p>The aim of this systematic review was to assess the antimicrobial effectiveness of silver nanoparticles (AgNPs) incorporated to different orthodontic bonding systems. Additionally, the review investigated the impact of AgNPs on the bonding properties of these materials. The hypothesis posed that the addition of AgNPs would enhance the antimicrobial efficacy of orthodontic bonding systems while maintaining their bonding properties. The systematic review employed a PICO-based search strategy, targeting in vitro studies focusing on the integration of nano silver particles into orthodontic bonding systems with potential antimicrobial activity. The intervention involved the use of nano silver in orthodontic bonding systems, with a comparison to systems lacking nano silver. The primary outcomes assessed were antimicrobial activity and shear bond strength (SBS). The search process, conducted without publication date restrictions, yielded 551 potential articles: 34 from PubMed, 360 from PubMed Central, 42 from Embase, 54 from Scopus, and 61 from Web of Science. Ultimately, a qualitative synthesis was conducted on 13 papers. The PRISMA diagram, visually represented the search strategy, screening process, and inclusion criteria. The study protocol was registered in PROSPERO CRD42023487656 to enhance transparency and adherence to systematic review guidelines. Quality assessment of the included studies was performed using the Newcastle-Ottawa Scale, revealing that the 13 articles meeting the inclusion criteria demonstrated a high level of evidence. Seven studies were included in the meta-analysis regarding shear bond strength. In summary, the synthesized findings from these studies strongly underscore the promising potential of orthodontic materials modified with AgNPs. These materials exhibit effective resistance against cariogenic bacteria without compromising bonding properties below clinical acceptability. Such innovative materials hold significant implications for advancing oral health within the realm of orthodontics.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"24 1","pages":"1342"},"PeriodicalIF":2.6,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11536928/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142581268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive evaluation of the antibacterial and antibiofilm activities of NiTi orthodontic wires coated with silver nanoparticles and nanocomposites: an in vitro study.","authors":"Omnia M Abdallah, Youssef Sedky, Heba R Shebl","doi":"10.1186/s12903-024-05104-w","DOIUrl":"10.1186/s12903-024-05104-w","url":null,"abstract":"<p><strong>Background: </strong>Fixed orthodontic appliances act as a niche for microbial growth and colonization. Coating orthodontic wires with antimicrobial silver nanoparticles (AgNPs) and nanocomposite was adopted in this study to augment the biological activity of these wires by increasing their antibacterial and antibiofilm properties and inhibiting bacterial infections that cause white spot lesions and lead to periodontal disease.</p><p><strong>Methods: </strong>Three concentrations of biologically synthesized AgNPs were used for coating NiTi wires. The shape, size, and charge of the AgNPs were determined. Six groups of 0.016 × 0.022-inch NiTi orthodontic wires, each with six wires, were used; and coated with AgNPs and nanocomposites. The antimicrobial and antibiofilm activities of these coated wires were tested against normal flora and multidrug-resistant bacteria (Gram-positive and Gram-negative bacterial isolates). The surface topography, roughness, elemental percentile, and ion release were characterized.</p><p><strong>Results: </strong>AgNPs and nanocomposite coated NiTi wires showed significant antimicrobial and antibiofilm activities. The chitosan-silver nanocomposite (CS-Ag) coated wires had the greatest bacterial growth inhibition against both Gram-positive and Gram-negative bacteria. The surface roughness of the coated wires was significantly reduced, impacting the surface topography and with recorded low Ni and Ag ion release rates.</p><p><strong>Conclusions: </strong>NiTi orthodontic wires coated with AgNPs, and nanocomposites have shown increased antimicrobial and antibiofilm activities, with decreased surface roughness, friction resistance and limited- metal ion release.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"24 1","pages":"1345"},"PeriodicalIF":2.6,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11539822/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142581271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alterations in subgingival microbiome and advanced glycation end-products levels in periodontitis with and without type 1 diabetes mellitus: a cross-sectional study.","authors":"Jialu Chen, Hong Wang, ShouShan Bu, Xiaofan Cheng, Xiaoya Hu, Min Shen, Hai Zhuang","doi":"10.1186/s12903-024-05089-6","DOIUrl":"10.1186/s12903-024-05089-6","url":null,"abstract":"<p><strong>Background: </strong>Existing studies predominantly focused on the relationship between periodontitis and type 2 diabetes mellitus (T2DM), with limited data on the association between periodontitis and type 1 diabetes mellitus (T1DM). This study aimed to examine the impact of T1DM and periodontitis on the subgingival microbiome and levels of advanced glycation end-products (AGEs).</p><p><strong>Methods: </strong>Samples were collected from four groups: T1DM, periodontitis (P), T1DM with periodontitis (DP), and periodontally and systemically healthy controls (Control). Subgingival microbiome composition and AGE levels were assessed using 16S rRNA gene sequencing and enzyme-linked immunosorbent assay (ELISA), respectively. Correlations between clinical indexes, microbiome composition, and AGEs were analyzed using Spearman correlation coefficient.</p><p><strong>Results: </strong>Alpha and beta diversity analyses revealed significant differences in bacterial diversity between the DP group and other groups. Linear discriminant analysis effect size (LEfSe) analysis identified specific bacteria influencing each group: Acinetobacter, Leptotrichia, Raoultibacter, and Veillonella in the Control group; Tannerella, Porphyromonas, Filifactor, and Treponema in the P group; and Lactobacillales in T1DM individuals. Prevotella and Selenomonas were notably influential in the DP group. PICRUSt2 analysis showed pathways alterations were concentrated in cell motility, translation, cell growth and death and metabolism in the DP and P groups. Spearman correlation analysis indicated a positive correlation between AGEs and periodontitis or diabetes-related parameters and AGEs were positively correlated with Haemophilus and Arachnia.</p><p><strong>Conclusions: </strong>The findings suggested that the composition and function of the subgingival microbiome in the P group with or without T1DM were significantly different. Additionally, AGEs were involved in the development of periodontitis even in absence of hyperglycemia.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"24 1","pages":"1344"},"PeriodicalIF":2.6,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11539332/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142581266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Masticatory function between chewing with and without wearing clear thermoplastic appliances.","authors":"Rungtiwa Jirawiwatsaree, Chidsanu Changsiripun","doi":"10.1186/s12903-024-05054-3","DOIUrl":"10.1186/s12903-024-05054-3","url":null,"abstract":"<p><strong>Background: </strong>Clear thermoplastic materials are used in a variety of oral appliances. In some situations, patients may wear clear thermoplastic appliances while eating. However, the effect of wearing clear thermoplastic appliances on chewing efficiency is unknown. This study aimed to evaluate the differences in masticatory function between chewing with and without wearing clear thermoplastic retainers over a 6-month period, and its associated factors.</p><p><strong>Methods: </strong>Thirty patients who received upper and lower clear retainers after debonding fixed appliances were examined for objective and subjective masticatory function at retainer delivery (T0), 3-month (T1), and 6-month follow-ups (T2) in two conditions: with and without wearing their retainers while chewing. The objective method used multiple sieves reported as the median particle size (MPS). The food intake ability (FIA) test served as the subjective method. Paired t-test was used to compare the outcomes between chewing with and without retainers at each evaluation time point. Repeated measures ANOVA followed by the Bonferroni post-hoc test was used to compare the outcomes between the three evaluating time points. Multivariable linear regression analysis was performed to assess whether age, sex, and extraction/non-extraction was associated with these effects.</p><p><strong>Results: </strong>The MPS was significantly greater when chewing with retainers compared with chewing without them at T0 (P < 0.05), however, it was not significantly greater at T1 and T2 (P > 0.05). The MPS with and without the retainers tend to decrease between T0, T1 and T2. In particular, the MPS while chewing with retainers significantly decreased between T0 and T1. The total FIA score and FIA subscores for hard and soft food were significantly lower when eating with retainers at T0 (P < 0.05), however, all FIA scores when eating without retainers did not significantly change between T0, T1, and T2. No significantly associated factors were identified.</p><p><strong>Conclusions: </strong>Wearing clear retainers while chewing decreases objective and subjective masticatory function immediately after completing orthodontic treatment. However, this significantly improved to levels comparable to chewing without retainers after a 3-month follow-up. Age, sex, and extraction/non-extraction treatment were not associated with the difference in masticatory function while chewing with and without wearing the retainers.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"24 1","pages":"1343"},"PeriodicalIF":2.6,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11539548/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142581273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}