{"title":"中东和北非（MENA）永久性和乳牙龋齿负担：1990年至2021年全球疾病负担研究的流行病学分析。","authors":"Negar Khorasani, Mahsa Nikaein, Sina Khayatzadeh, Amirmohammad Ansari Feyzabadi, Narges Panahandeh","doi":"10.1186/s12903-025-06774-w","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Dental caries, a prevalent non-communicable disease (NCD), remains a significant health challenge worldwide, especially in the Middle East and North Africa (MENA) region. In this study, we analyzed and compared the burden of dental caries in the MENA region from 1990 to 2021 based on Global Burden of Disease (GBD 2021) database.</p><p><strong>Methods: </strong>Data from the GBD 2021 study database was utilized to assess the incidence, prevalence, and years lived with disability (YLD) for dental caries across 21 MENA countries. The study estimates age-standardized rates, considering variables such as age, gender, and region. Additionally, the relationship between dental caries and the Socio-Demographic Index (SDI) was examined.</p><p><strong>Results: </strong>The age-standardized incidence rate (ASIR) of permanent dental caries (PDC) in the MENA region increased from 31,592.38 per 100,000 in 1990 to 31,920.12 in 2021 with total percentage change (TPC) of 0.01 (-0.01-0.03). The ASIR of deciduous dental caries (DDC) in MENA region decreased from 19388.28 in 1990 to 16170.92 with TPC of -0.17 (-0.38-0.15). Additionally, the age-standardized prevalence rate (ASPR) of PDC in the MENA region decreased from 1990 to 2021 with the TPC of -0.04 (-0.06 - -0.02). Likewise, the ASPR of DDC decreased from 1990 to 2021 with the TPC of -0.06 (-0.24- 0.21). The age-standardized YLD rate (ASYR) for both PDC and DDC decreased from 1990 to 2021 with the TPC of -0.05 (-0.07- -0.02) and - 0.04 (-0.36- 0.38), respectively.</p><p><strong>Conclusions: </strong>The findings underscore the need for enhanced preventive efforts and healthcare access in the MENA region, particularly in low-income countries. Further attention is required to address age and gender disparities, with a focus on the most vulnerable populations.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"1535"},"PeriodicalIF":3.1000,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12502493/pdf/","citationCount":"0","resultStr":"{\"title\":\"Burden of permanent and deciduous dental caries in middle East and North Africa (MENA): an epidemiological analysis of global burden of disease study from 1990 to 2021.\",\"authors\":\"Negar Khorasani, Mahsa Nikaein, Sina Khayatzadeh, Amirmohammad Ansari Feyzabadi, Narges Panahandeh\",\"doi\":\"10.1186/s12903-025-06774-w\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Dental caries, a prevalent non-communicable disease (NCD), remains a significant health challenge worldwide, especially in the Middle East and North Africa (MENA) region. In this study, we analyzed and compared the burden of dental caries in the MENA region from 1990 to 2021 based on Global Burden of Disease (GBD 2021) database.</p><p><strong>Methods: </strong>Data from the GBD 2021 study database was utilized to assess the incidence, prevalence, and years lived with disability (YLD) for dental caries across 21 MENA countries. The study estimates age-standardized rates, considering variables such as age, gender, and region. Additionally, the relationship between dental caries and the Socio-Demographic Index (SDI) was examined.</p><p><strong>Results: </strong>The age-standardized incidence rate (ASIR) of permanent dental caries (PDC) in the MENA region increased from 31,592.38 per 100,000 in 1990 to 31,920.12 in 2021 with total percentage change (TPC) of 0.01 (-0.01-0.03). The ASIR of deciduous dental caries (DDC) in MENA region decreased from 19388.28 in 1990 to 16170.92 with TPC of -0.17 (-0.38-0.15). Additionally, the age-standardized prevalence rate (ASPR) of PDC in the MENA region decreased from 1990 to 2021 with the TPC of -0.04 (-0.06 - -0.02). Likewise, the ASPR of DDC decreased from 1990 to 2021 with the TPC of -0.06 (-0.24- 0.21). The age-standardized YLD rate (ASYR) for both PDC and DDC decreased from 1990 to 2021 with the TPC of -0.05 (-0.07- -0.02) and - 0.04 (-0.36- 0.38), respectively.</p><p><strong>Conclusions: </strong>The findings underscore the need for enhanced preventive efforts and healthcare access in the MENA region, particularly in low-income countries. Further attention is required to address age and gender disparities, with a focus on the most vulnerable populations.</p>\",\"PeriodicalId\":9072,\"journal\":{\"name\":\"BMC Oral Health\",\"volume\":\"25 1\",\"pages\":\"1535\"},\"PeriodicalIF\":3.1000,\"publicationDate\":\"2025-10-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12502493/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"BMC Oral Health\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1186/s12903-025-06774-w\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"BMC Oral Health","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s12903-025-06774-w","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
Burden of permanent and deciduous dental caries in middle East and North Africa (MENA): an epidemiological analysis of global burden of disease study from 1990 to 2021.
Background: Dental caries, a prevalent non-communicable disease (NCD), remains a significant health challenge worldwide, especially in the Middle East and North Africa (MENA) region. In this study, we analyzed and compared the burden of dental caries in the MENA region from 1990 to 2021 based on Global Burden of Disease (GBD 2021) database.
Methods: Data from the GBD 2021 study database was utilized to assess the incidence, prevalence, and years lived with disability (YLD) for dental caries across 21 MENA countries. The study estimates age-standardized rates, considering variables such as age, gender, and region. Additionally, the relationship between dental caries and the Socio-Demographic Index (SDI) was examined.
Results: The age-standardized incidence rate (ASIR) of permanent dental caries (PDC) in the MENA region increased from 31,592.38 per 100,000 in 1990 to 31,920.12 in 2021 with total percentage change (TPC) of 0.01 (-0.01-0.03). The ASIR of deciduous dental caries (DDC) in MENA region decreased from 19388.28 in 1990 to 16170.92 with TPC of -0.17 (-0.38-0.15). Additionally, the age-standardized prevalence rate (ASPR) of PDC in the MENA region decreased from 1990 to 2021 with the TPC of -0.04 (-0.06 - -0.02). Likewise, the ASPR of DDC decreased from 1990 to 2021 with the TPC of -0.06 (-0.24- 0.21). The age-standardized YLD rate (ASYR) for both PDC and DDC decreased from 1990 to 2021 with the TPC of -0.05 (-0.07- -0.02) and - 0.04 (-0.36- 0.38), respectively.
Conclusions: The findings underscore the need for enhanced preventive efforts and healthcare access in the MENA region, particularly in low-income countries. Further attention is required to address age and gender disparities, with a focus on the most vulnerable populations.
期刊介绍：
BMC Oral Health is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of disorders of the mouth, teeth and gums, as well as related molecular genetics, pathophysiology, and epidemiology.
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