BMC Oral Health最新文献

{"title":"Postural effects of dental loupes in pediatric dental practice?","authors":"Rumeysa Çınar, Sema Aydınoğlu, İpek Arslan, Dilara Nil Günaçar","doi":"10.1186/s12903-025-05766-0","DOIUrl":"10.1186/s12903-025-05766-0","url":null,"abstract":"<p><strong>Background: </strong>Pediatric dentists may encounter musculoskeletal disorders (MSD) when they cannot maintain neutral postures during dental treatments. It is known that dental loupes (DL) can contribute to improving the ergonomic posture of dentists during treatment. This study aims to investigate the effect of wearing DL on the working posture of pediatric dentists.</p><p><strong>Methods: </strong>In pulpotomy procedures performed with DL in 23 patients and without DL in 23 patients, photographs were taken at a total of 3 times in each patient: at the beginning of the procedure, 15^th, and 30^th minutes. The working postures of the clinicians were analyzed using the Modified-Dental Operator Posture Assessment Instrument (M-DOPAI) method through these photographs. The differences between the working postures of pediatric dentists in both groups were analyzed using the Wilcoxon test. The Friedman test determined the statistical relationship between pediatric dentists' time-dependent working postures.</p><p><strong>Results: </strong>At the beginning, 15^th, and 30^th minutes of treatment, the neck and shoulder postures and the total M-DOPAI scores of clinicians using DL were significantly lower than those working without DL (P < 0.05). However, no significant difference was found among the total scores determined at different time intervals during the treatment (P > 0.05).</p><p><strong>Conclusions: </strong>The use of dental loupes has been proven to lower ergonomic risk levels related to the working postures of pediatric dentists. By promoting a more neutral neck and shoulder position, dental loupes may help reduce the risk of occupational musculoskeletal disorders.</p><p><strong>Trial registration: </strong>The trial protocol was retrospectively registered ID NCT06799585 ( https://clinicaltrials.gov/ ); Jan 29, 2025.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"432"},"PeriodicalIF":2.6,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938647/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of the use of whitening mouthwash after home bleaching on the color stability and surface hardness of enamel.","authors":"Iklima Mehmethanoglu, Ipek Cubukcu, Neslihan Celik, Pinar Gul","doi":"10.1186/s12903-025-05787-9","DOIUrl":"10.1186/s12903-025-05787-9","url":null,"abstract":"<p><strong>Background: </strong>To evaluate the effectiveness of whitening mouthwashes, both with and without hydrogen peroxide (HP), after at-home teeth whitening in preserving the achieved whiteness and assessing their impact on enamel surface hardness.</p><p><strong>Methods: </strong>One hundred extracted human premolar teeth were divided into two groups, and home bleaching agents (Philips Zoom NiteWhite 22% Carbamide Peroxide, Ultradent Opalescence PF 16% Carbamide Peroxide) were applied to the groups. The teeth subjected to home bleaching were further divided into five subgroups, and each subgroup underwent a four-week cycle of application of a coloring agent and whitening mouthwash (Colgate Optic White (COW)(%2 HP), Rocs Black Edition (Rocs) (%1 HP), SPLAT Professional Bioactive gargle white Plus (SPLAT) (Ananas sativus fruit extract containing), Listerine Advanced White (Listerine) (Pyrophsphate containing), and distilled water (DW) (control)). Color and microhardness measurements were recorded at baseline, after home bleaching, and after treatment with whitening mouthwashes.</p><p><strong>Results: </strong>Compared with those treated with Opalescence PF, the samples treated with Zoom achieved a significantly greater degree of whitening (p < 0.001). When the effects of postwhitening mouthwash were evaluated (ΔE₀₀₂), Listerine presented the lowest ΔE₀₀₂ value in both home bleaching groups, whereas the control group presented the highest ΔE₀₀₂ value. Both home-bleaching agents caused a significant increase in the initial WI_D values (p < 0.05). After home-bleaching, the increased WI_D values (WI_D2) significantly decreased in all mouthwash groups following exposure to the staining and whitening mouthwash cycle (WI_D3) (p < 0.05). The impact of home bleaching agents on microhardness was not significantly different (p = 0.151). When we examined the impact of whitening mouthwashes on microhardness, in the Zoom group, no statistically significant difference was observed in surface hardness (p > 0.05). However, in the Opalescence PF group, only the Listerine group showed a statistically significant increase (p < 0.05).</p><p><strong>Conclusions: </strong>Higher concentrations of carbamide peroxide provide faster and more effective whitening. Whitening mouthwash containing HP and pyrophosphate is effective in maintaining tooth whiteness after home bleaching; however, its impact on enamel microhardness depends on the formulation. Notably, only Listerine in the Opalescence PF group significantly increased surface hardness. Given the drawbacks of HP, pyrophosphate-based mouthwash may serve as a safer alternative.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"437"},"PeriodicalIF":2.6,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11948628/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of methods for detecting mandibular lingula and can antilingula be used in lingula mandibula detection?","authors":"Emre Balaban, Taha Emre Köse, Dilara Nil Günaçar, Muhammed Enes Naralan, Merve Gonca","doi":"10.1186/s12903-025-05788-8","DOIUrl":"10.1186/s12903-025-05788-8","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study is to evaluate the relationship between anatomical reference points used during orthognathic surgery and to minimize the risks of iatrogenic neurovascular damage.</p><p><strong>Materials and methods: </strong>This retrospective study included cone-beam computed tomography (CBCT) images involving the mandible from patients who visited Recep Tayyip Erdoğan University Faculty of Dentistry between January 2018 and September 2023. The age range of the included individuals was set between 18 and 80 years. Horizontal and vertical distances between mandibular anatomical structures, such as the lingula mandibula (LM), mandibular foramen (MF), antilingula (AL), and surrounding structures were measured using CBCT software. Individuals with intraosseous pathology, insufficient image quality, or a history of surgical/orthodontic treatment were excluded from the study.</p><p><strong>Results: </strong>A total of 240 hemimandibles from 120 patients were analyzed (55.83% female, 44.17% male; mean age: 46.78 ± 15.30 years). Significant differences were identified in LM positions according to different AL types. The LM was found to be more inferior and posterior relative to hill and ridge type ALs, while it was more anterior relative to plateau type ALs. In 26.25% of mandibular rami, AL was not detected.</p><p><strong>Conclusion: </strong>The position of the AL can serve as a guide in determining the osteotomy line during inferior vertical ramus osteotomy (IVRO). However, relying solely on AL as a reference point may increase the risk of inferior alveolar nerve (IAN) injury. Preoperative tomographic evaluations to determine the relationships among LM, MF, and AL can provide a safer approach in surgical planning, reduce complications, and help protect neurovascular structures.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"430"},"PeriodicalIF":2.6,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938737/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the effect of manual lymphatic drainage method on edema, pain and trismus after impacted bilateral mandibular third molar surgery: a randomized clinical trial.","authors":"Murat Ulu, Nuri Ünal, Onur Şahin, Yasemin Kayalı","doi":"10.1186/s12903-025-05817-6","DOIUrl":"10.1186/s12903-025-05817-6","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to evaluate the effect of manual lymphatic drainage (MLD) on edema, pain and trismus after impacted mandibular third molar surgery.</p><p><strong>Materials and methods: </strong>46 patients with bilateral impacted mandibular third molar teeth were included in our study. The study was designed as a split-mouth, single-blinded, and controlled randomized clinical trial. Patients in the study group received MLD therapy, while the control group followed routine postoperative care including drug treatment. After extractions, the records were compared statistically and edema, pain and trismus parameters were evaluated on the 3rd and 7th days. The primary outcome variables was swelling and secondary outcome variables were pain and trismus. Swelling was evaluated using the 3dMD FACE SYSTEM (3dMD, Atlanta, GA). To assess pain, the Visual Analog Scale (VAS) was used and trismus was measured using with a digital caliper.</p><p><strong>Results: </strong>The present study was conducted on a total of 46 patients, aged between 18 and 26 years (18.7174 ± 1.50056), with bilaterally similar, symmetrical impacted mandibular third molars. The group consisted of 14 males (30.4%) and 32 females (69.6%). Postoperative edema, pain and trismus were found to be significantly lower in the MLD group compared to the control group (p < 0.05).</p><p><strong>Conclusion: </strong>MLD technique is a useful method for reducing postoperative morbidity after impacted third molar extraction. The MLD technique is a simple method free from undesirable side effects and may be more effective than classical methods in reducing edema, pain and trismus after third molar extraction.</p><p><strong>Trial registration: </strong>The trial was registered retrospectively on ClinicalTrials.gov (ID: NCT06787027, on 22/01/2025). Approved by Izmir Katip Celebi University Clinical Research Ethics Committee (Decision No: ID 19, on 15/02/2018).</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"438"},"PeriodicalIF":2.6,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11948945/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of ozone therapy in dentistry with approach of healing, pain management, and therapeutic outcomes: a systematic review of clinical trials.","authors":"Maryam Rezaeianjam, Aynaz Khabazian, Tanaz Khabazian, Fatemeh Ghorbani, Tayebeh Abbasi, Shima Asghari, Fatemeh Heidari, Aida Shiri, Maziar Naderi","doi":"10.1186/s12903-025-05790-0","DOIUrl":"10.1186/s12903-025-05790-0","url":null,"abstract":"<p><p>Ozone therapy has emerged as a promising treatment modality in dentistry due to its antimicrobial and healing properties. This systematic review aimed to evaluate the recent clinical trials on ozone therapy in dentistry and its impact on therapeutic outcomes. A comprehensive literature search was conducted across multiple databases, including Web of Science, PubMed, and Scopus from January 2018 to December 2024, identifying studies that investigated the use of ozone in dental applications. The findings demonstrated that ozone therapy is effective in improving periodontal health, healing soft tissue after dental implant surgery, and reducing postoperative discomfort. The combination of scaling and root planing with gaseous ozone therapy showed superior periodontal response rates. The use of ozone during endodontics procedures resulted in reduced post-treatment pain, while ozonated materials showed promise in the management of dentinal hypersensitivity. However, it is not recommended in restorative dentistry due to potential adverse effects on dentinal bond strength. The findings of this systematic review supported the integration of ozone therapy into dentistry as an adjunctive therapy. More research is needed to elucidate its mechanisms, optimize application techniques, and evaluate long-term outcomes for patient safety and treatment effectiveness.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"433"},"PeriodicalIF":2.6,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938743/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of an adult patient with severe dental crowding by applying asymmetric extraction, fixed appliance, and micro-implant anchorage: a case report.","authors":"Huixin Xue, Siyi Xu, Yezi Qi, Leilei Xue, Xinxin Ni, Liqi Xu, Qingshan Li, Jun Lin","doi":"10.1186/s12903-025-05808-7","DOIUrl":"10.1186/s12903-025-05808-7","url":null,"abstract":"<p><strong>Background: </strong>Severe dental crowding and protrusion often necessitate symmetric extraction for correction. However, asymmetric extraction may serve as a viable, albeit challenging, treatment option when the prognosis of individual tooth is poor. In this report, we present a case where asymmetric extraction was employed to address severe dental crowding and deviated midlines, resulting in satisfactory outcomes following retention.</p><p><strong>Case presentation: </strong>We report a case of a 31-year-old woman with severe dental crowding and deviated dental midlines. A fixed appliance, micro-implant anchorage, and asymmetric extraction, including a mandibular canine with severe buccal malposition, were applied to the patient. The treatment outcomes demonstrated successful achievement of the treatment objectives, with well-aligned teeth exhibiting solid interdigitation and the dental midlines aligned with the facial midline. At the 21-month follow-up, midline stability, favorable occlusal interdigitation, and improved smile line were observed.</p><p><strong>Conclusions: </strong>Asymmetric extraction may be considered a viable approach for patients with individual tooth of poor prognosis. Treatment stability can be achieved through well-interdigitated occlusion and the use of various retention methods.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"436"},"PeriodicalIF":2.6,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938769/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral health practices and literacy in Hungarian diabetes patients: insights from a pilot-study using a WHO-adapted questionnaire.","authors":"Klaudia Lipták, Laura Lipták, Kata Sára Haba, Dorottya Bányai, Dániel S Veres, Noémi Katinka Rózsa, Péter Hermann, Dániel Végh","doi":"10.1186/s12903-025-05820-x","DOIUrl":"10.1186/s12903-025-05820-x","url":null,"abstract":"<p><strong>Introduction: </strong>This study aimed to compare the self-reported oral health status, knowledge, and habits of individuals living with diabetes mellitus and healthy controls. To achieve this, the modified version of the World Health Organization's Oral Health Questionnaire for Adults (ANNEX 7; Google Forms) was employed for data collection.</p><p><strong>Methods: </strong>The study included 99 diabetes patients (33 with type 1 and 66 with type 2 diabetes mellitus) and 102 non-diabetic controls. Logistic regression models, adjusted for demographic factors, were applied to examine associations between oral hygiene practices, dietary habits, and the number of natural teeth.</p><p><strong>Results: </strong>Individuals with diabetes exhibited a greater frequency of oral pathological conditions. Despite 74% of people with diabetes mellitus (PwDM) brushing their teeth twice daily, they had fewer natural teeth compared to the control group (20 or more teeth: DM: 54.5%, controls: 70.6%). In our study, there is no evidence that number of teeth is dependent on HbA1c levels, and we found that neither age nor gender influenced the change in HbA1c levels. Lower interdental cleaning habits and frequent fruit consumption were identified as significant risk factors for severe tooth loss.</p><p><strong>Conclusion and clinical relevance: </strong>This study highlights significant oral health disparities in diabetes patients, particularly those with T2DM, who reported poorer oral health, more frequent denture use, and fewer natural teeth. These findings underscore the need for integrating oral health education, preventive care, and interdisciplinary collaboration into diabetes management to improve overall health outcomes.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"431"},"PeriodicalIF":2.6,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938766/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiological trends and age-period-cohort effects on periodontal diseases incidence across the BRICS from 1992 to 2021.","authors":"Xiaochan Wang, Yuting Xu, Xiangming Ma, Ruixing Nan, Yuhang Wu, Peiyu Cheng","doi":"10.1186/s12903-025-05796-8","DOIUrl":"10.1186/s12903-025-05796-8","url":null,"abstract":"<p><strong>Background: </strong>Periodontal diseases are prevalent oral conditions, particularly burdensome in developing countries. This study examines global and BRICS countries' changing trends in periodontal diseases incidence from 1992 to 2021, focusing on associations with age, period, and cohort effects.</p><p><strong>Materials and methods: </strong>A cross-sectional burden of disease study was conducted. Data on the total population and periodontal diseases cases, all-age incidence rate, age-standardized incidence rate, and relative change in periodontal diseases incidence from 1992 to 2021 within BRICS were obtained from the Global Burden of Disease study (GBD) 2021. Furthermore, the Age-Period-Cohort (APC) model with an intrinsic estimator (IE) algorithm was employed to assess the effects of net drift, local drift, age, period, and cohort on the incidence rates of periodontal diseases over specific time periods.</p><p><strong>Results: </strong>Globally, the new cases of periodontal diseases in 2021 were reported at 8961 thousand (95% uncertainty intervals: 7907, 10101), reflecting a 71.21% increase compared to 1992. In 2021, the age-standardized incidence rate of periodontal diseases across the BRICS countries ranged from 600.50 (95% uncertainty intervals: 481.27, 763.54) per 100,000 population in South Africa to 1268.96 (95% uncertainty intervals: 1119.16, 1409.94) per 100,000 population in India. The age distribution of periodontal diseases cases was relatively stable globally and among BRICS countries from 1992 to 2021. Countries exhibited similar age-effect patterns, with increasing risk with increasing age, and varying period and cohort effects, indicative of differential control measures and temporal incidence trends.</p><p><strong>Conclusions: </strong>Brazil, India, and China experienced an increasing trend in the age-standardized incidence rates of periodontal diseases from 1992 to 2021, in contrast to the declining trends observed in the Russian Federation and South Africa. Furthermore, the APC analysis indicates the intricate dynamics of age, period, and cohort influences on periodontal diseases incidence. Distinct national trajectories, shaped by varying socioeconomic, cultural, and historical frameworks, highlight that public health initiatives must be meticulously customized to mitigate and control the periodontal diseases burden across diverse settings.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"434"},"PeriodicalIF":2.6,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938746/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the postoperative effect of low laser therapy and platelet rich fibrin on mandibular third molar surgery: a randomized study.","authors":"Beste Erismen Agan, Lokman Onur Uyanık, Ceren Melahat Donmezer","doi":"10.1186/s12903-025-05828-3","DOIUrl":"10.1186/s12903-025-05828-3","url":null,"abstract":"<p><strong>Background: </strong>This study investigates the postoperative benefits of low-level laser therapy (LLLT) and platelet-rich fibrin (PRF) in enhancing patient comfort and reducing complications after mandibular third molar extractions.</p><p><strong>Methods: </strong>Sixty patients with vertically impacted mandibular third molars were randomly assigned to one control and three test groups (n = 15 each). In Group 1, PRF was applied to the socket post-extraction. In Group 2, PRF was combined with LLLT (B-Cure Dental Laser, 808 nm wavelength, 4 J/cm² energy density, continuous wave) applied extra-orally for three days post-surgery. Group 3 received LLLT alone. Group 4 (control group) underwent traditional osteotomy without additional treatments. All patients were prescribed 875/125 mg amoxicillin/clavulanic acid twice daily for five days.</p><p><strong>Results: </strong>Postoperative parameters such as pain, swelling, analgesic use, and trismus were assessed on days 1, 2, 3, and 7. Significant improvements in pain, swelling, and trismus were observed in Groups 2 and 3 compared to the control (p < 0.001). Swelling was also significantly reduced in Group 1 compared to the control.</p><p><strong>Conclusions: </strong>The study demonstrated favorable clinical outcomes in the LLLT and PRF groups, suggesting that both treatments could be promising strategies for improving postoperative recovery in terms of comfort and reduced complications.</p><p><strong>Trial registiration: </strong>Clinicaltrials.gov ID: NCT06262945. The trial was first registered on 16/02/2024. Retrospectively registered.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"427"},"PeriodicalIF":2.6,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11934512/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cachexia in oral squamous cell carcinoma Sudanese patients: an exploratory study.","authors":"Safaa Merghani Awadallah, Hind Ahmed Osman Elhag, Yousif Eltohami","doi":"10.1186/s12903-025-05793-x","DOIUrl":"10.1186/s12903-025-05793-x","url":null,"abstract":"<p><strong>Background: </strong>Cachexia status is a drastic issue in cancer patients. The main goal of this study; which is considered the first of its kind in Sudan, was to enhance our understanding of the clinical implications of oral cancer cachexia. Newly diagnosed Sudanese patients with oral squamous cell carcinoma (OSCC) were evaluated for the incidence and impact of cachexia.</p><p><strong>Methods: </strong>This is a longitudinal descriptive study conducted at Khartoum Teaching Dental Hospital before April 2023. A number of 40 OSCC participants above 18 years old were analyzed for Cachexia based on weight loss, low hemoglobin levels, albumin levels, elevated C-reactive protein, decreased mid-upper arm circumference, loss of appetite, and anorexia. Data were collected over three visits, and analyzed using descriptive and bivariate statistics.</p><p><strong>Results: </strong>The study included 40 newly diagnosed patients with OSCC, with a mean of age 56.8 years. The incidence of cachexia was 33.2% before surgery, 55% one month postoperatively, and 65% six months later. Cachexia was significantly correlated (p < 0.05) with delayed wound healing (p = 0.008), prolonged nasogastric feeding tube usage (p = 0.023), interrupted adjuvant therapy (p = 0.003), and mortality (p = 0.007). Low BMI, loss of appetite, food intake, low hemoglobin, and elevated CRP were significant diagnostic criteria as well (p < 0.05).</p><p><strong>Conclusions: </strong>In this study, Cachexia was found to be a critical prognostic factor for OSCC patients. Larger-scale clinical research in Sudan is needed to provide definitive findings and strategies to support nutritional status during therapy.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":"25 1","pages":"428"},"PeriodicalIF":2.6,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11934434/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}