Biological Trace Element Research最新文献_第7页

Antagonistic Effects, Sources, and Distribution of Selenium and Toxic Metals in Fish from Selenium-Rich and High Cadmium Areas, Dashan Region, China. 中国大山地区富硒高镉地区鱼类体内硒与有毒金属的拮抗作用、来源及分布。

IF 3.4 3区生物学

Biological Trace Element Research Pub Date : 2024-12-01 Epub Date: 2024-02-09 DOI: 10.1007/s12011-024-04092-w

Bing Zhao, Duozhi Tu, Bowen Kong, Ting Yue, Shoubiao Zhou, Shuai Liu, Xiaoguo Wu

{"title":"Antagonistic Effects, Sources, and Distribution of Selenium and Toxic Metals in Fish from Selenium-Rich and High Cadmium Areas, Dashan Region, China.","authors":"Bing Zhao, Duozhi Tu, Bowen Kong, Ting Yue, Shoubiao Zhou, Shuai Liu, Xiaoguo Wu","doi":"10.1007/s12011-024-04092-w","DOIUrl":"10.1007/s12011-024-04092-w","url":null,"abstract":"The Gongxin River is one of the main rivers in the Dashan Region of Anhui Province in China, which is a Se-rich and high-Cd area, but no research has focused on the concentration, source, antagonism, and health risks of Se and TMs in fish. In this study, 120 fish samples (14 species), 24 sediment samples, and 24 water samples were collected to investigate the antagonistic effects, sources, and health risks of TMs and Se in fish from a typical selenium-rich and high cadmium region. Zn and Se in fish from the Gongxin River were higher than in the background, which might be attributed to the different feeding habits of different fish species. The apparent antagonism between Se and Cu, Pb, and Cd was explored, and the results showed that 30%, 75%, and 100% of the Se/Cu, Se/Pb, and Se/Cd ratios were greater than one, indicating that Cu, Pb, and Cd in fish might be combined with or detoxicated by Se. The source analysis of the elements showed that the geological background was the source of TMs and Se in fish samples. The amounts of Se and TMs were all within China's acceptable level guidelines, signifying no harm to citizens from eating fish.","PeriodicalId":8917,"journal":{"name":"Biological Trace Element Research","volume":" ","pages":"5690-5696"},"PeriodicalIF":3.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139705923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Plasma Levels of Magnesium, Calcium, Calcium to Magnesium Ratio, and Associations with Metabolic Syndrome and Cardiometabolic Risk Factors. 血浆中的镁、钙、钙镁比水平以及与代谢综合征和心脏代谢风险因素的关系。

IF 3.4 3区生物学

Biological Trace Element Research Pub Date : 2024-12-01 Epub Date: 2024-02-12 DOI: 10.1007/s12011-024-04088-6

Melissa Nunes Moia, Severina Carla Vieira Cunha Lima, Francisca Leide da Silva Nunes, Salomão Israel Monteiro Lourenço Queiroz, Dirce Maria Lobo Marchioni, Lucia Fátima Campos Pedrosa, Fernando Barbosa, Clélia de Oliveira Lyra, Karine Cavalcanti Maurício Sena-Evangelista

{"title":"Plasma Levels of Magnesium, Calcium, Calcium to Magnesium Ratio, and Associations with Metabolic Syndrome and Cardiometabolic Risk Factors.","authors":"Melissa Nunes Moia, Severina Carla Vieira Cunha Lima, Francisca Leide da Silva Nunes, Salomão Israel Monteiro Lourenço Queiroz, Dirce Maria Lobo Marchioni, Lucia Fátima Campos Pedrosa, Fernando Barbosa, Clélia de Oliveira Lyra, Karine Cavalcanti Maurício Sena-Evangelista","doi":"10.1007/s12011-024-04088-6","DOIUrl":"10.1007/s12011-024-04088-6","url":null,"abstract":"Magnesium and calcium are elements that have been associated with cardiometabolic risk factors related to metabolic syndrome (MetS). However, there are gaps in the knowledge regarding the impact of the calcium to magnesium (Ca/Mg) ratio in plasma. Thus, we aim to evaluate the associations between magnesium and calcium levels in plasma, and the Ca/Mg ratio in plasma with MetS components and other cardiometabolic risk factors. This cross-sectional study was carried out with 112 adults and older people, distributed into groups with (n = 60) and without MetS (n = 52). We evaluated sociodemographic, anthropometric, and biochemical data. Magnesium and calcium levels in plasma were measured by inductively coupled plasma mass spectrometry technique (ICP-MS). There was a high frequency of MetS, with no significant differences in magnesium and calcium levels and Ca/Mg ratio in plasma observed between groups. There were no associations between magnesium and MetS components or other cardiometabolic risk factors (all p > 0.05). Calcium levels were associated with total cholesterol (β = - 0.020; p = 0.000) and high-density lipoprotein cholesterol (HDL-c) (β = - 0.046; p = 0.005). The total cholesterol (β = - 0.025; p = 0.000) and low-density lipoprotein cholesterol (LDL-c) (β = 0.017; p = 0.020) were preditors of the Ca/Mg ratio. These results indicate important associations of calcium and the Ca/Mg ratio in plasma with cardiometabolic risk factors related to MetS.","PeriodicalId":8917,"journal":{"name":"Biological Trace Element Research","volume":" ","pages":"5307-5318"},"PeriodicalIF":3.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139721437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Therapeutic Potential of Green Synthesized Silver Nanoparticles for Promoting Wound-Healing Process in Diabetic Mice. 绿色合成银纳米粒子促进糖尿病小鼠伤口愈合过程的治疗潜力

IF 3.4 3区生物学

Biological Trace Element Research Pub Date : 2024-12-01 Epub Date: 2024-02-14 DOI: 10.1007/s12011-024-04094-8

Riffat Iqbal, Amna Asghar, Arslan Habib, Shaista Ali, Sadaf Zahra, Muhammad Imran Hussain, Ahmad Bilal Ahsan, Yulai Liang

{"title":"Therapeutic Potential of Green Synthesized Silver Nanoparticles for Promoting Wound-Healing Process in Diabetic Mice.","authors":"Riffat Iqbal, Amna Asghar, Arslan Habib, Shaista Ali, Sadaf Zahra, Muhammad Imran Hussain, Ahmad Bilal Ahsan, Yulai Liang","doi":"10.1007/s12011-024-04094-8","DOIUrl":"10.1007/s12011-024-04094-8","url":null,"abstract":"Diabetes is a serious metabolic disorder characterized by abnormal glucose levels in the body. Delayed wound healing is a severe diabetes complication. Nanotechnology represents the latest advancement in treating diabetic wounds through nanoparticles (NPs). In this study, silver nanoparticles (AgNPs) were synthesized using a green method involving cucumber pulp extract. The synthesis was confirmed using techniques including ultraviolet-visible spectrophotometry (UV-Vis), Fourier-transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), scanning electron microscopy (SEM), and energy dispersive X-ray (EDX). To evaluate wound-healing properties, mouse models were utilized with wounds induced by excision on the dorsal surface. An ointment containing silver nanoparticles was applied to assess its healing potential. Additionally, antibacterial and antioxidant activities were examined using agar well diffusion and DPPH scavenging methods, respectively. The results demonstrated that the ointment prepared with green synthesized AgNPs effectively healed the wounds within 15 days, while also exhibiting antibacterial and antioxidant properties. Therefore, it can be concluded that due to its efficacy in biological activities, silver nanoparticles can be employed in the treatment of diabetic wounds.","PeriodicalId":8917,"journal":{"name":"Biological Trace Element Research","volume":" ","pages":"5545-5555"},"PeriodicalIF":3.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139728852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Coffee Consumption in Association with Serum Iron Levels: A Cross-sectional Study. 咖啡饮用量与血清铁水平的关系：一项横断面研究

IF 3.4 3区生物学

Biological Trace Element Research Pub Date : 2024-12-01 Epub Date: 2024-02-23 DOI: 10.1007/s12011-024-04112-9

Abdullah I Aedh

{"title":"Coffee Consumption in Association with Serum Iron Levels: A Cross-sectional Study.","authors":"Abdullah I Aedh","doi":"10.1007/s12011-024-04112-9","DOIUrl":"10.1007/s12011-024-04112-9","url":null,"abstract":"This study determines the association between adult Saudi Arabian coffee consumption and serum iron levels. The extensive Saudi Arabian population, including both sexes - male and female, participated in this cross-sectional community-based study from 1 October 2020 to 31 June 2022. The participants were selected arbitrarily using the systematic simple random position. The current study enrolled 113 participants with a mean age of 33 years, including 94 (83.2%) females and 19 (16.8%) males. The concentration of iron absorption assessed among 62 individuals who participated in the group of occasional coffee drinkers was higher (54.9%) than the 51 individuals who participated in the group of regular coffee drinkers (45.1%). In daily coffee consumption, paired samples statistics in mean baseline WBC level (103/μl) was 6.396. On day 31 of June 2022, WBC level (103/μl) was 6.114. Paired samples statistics in mean baseline iron level was 44.29. On day 31 of June 2022, iron level was 72.15. The paired samples correlation in baseline and day 31 iron levels was 0.719, with a significant difference of 0.000. It is critical to acquire the most recent information and local statistics on the frequency of low serum iron levels in Saudi Arabia's diverse adult population. The adult population of Saudi Arabia correlates with coffee consumption and changes in serum ferritin or iron levels and WBC counts. Neither the WBC numbers nor the iron levels were significantly altered. Further research is needed to determine the potential mechanisms causing these relationships.","PeriodicalId":8917,"journal":{"name":"Biological Trace Element Research","volume":" ","pages":"5386-5394"},"PeriodicalIF":3.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139939477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Therapeutic Potential of Aloe vera and Aloe vera-Conjugated Silver Nanoparticles on Mice Exposed to Hexavalent Chromium. 芦荟和芦荟共轭银纳米粒子对暴露于六价铬的小鼠的治疗潜力

IF 3.4 3区生物学

Biological Trace Element Research Pub Date : 2024-12-01 Epub Date: 2024-03-13 DOI: 10.1007/s12011-024-04105-8

Tooba Nauroze, Shaukat Ali, Shagufta Andleeb, Chaman Ara, Iqra Liaqat, Hina Mushtaq, Samaira Mumtaz, Lubna Kanwal, Afshan Syed Abbas, Shumaila Mumtaz, Muhammad Adeel Farooq, Istaqlal Hussain Khan

{"title":"Therapeutic Potential of Aloe vera and Aloe vera-Conjugated Silver Nanoparticles on Mice Exposed to Hexavalent Chromium.","authors":"Tooba Nauroze, Shaukat Ali, Shagufta Andleeb, Chaman Ara, Iqra Liaqat, Hina Mushtaq, Samaira Mumtaz, Lubna Kanwal, Afshan Syed Abbas, Shumaila Mumtaz, Muhammad Adeel Farooq, Istaqlal Hussain Khan","doi":"10.1007/s12011-024-04105-8","DOIUrl":"10.1007/s12011-024-04105-8","url":null,"abstract":"Hexavalent chromium (Cr (VI)) is a hazardous heavy metal that induces hepatotoxicity and nephrotoxicity. Thus, this study was planned to explore the ameliorating capacity of Aloe vera leaf gel extract (AV) and their conjugated silver nanoparticles (AVNP) against Cr (VI) induced hepatotoxicity and renal toxicity. The organ indices, level of alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, malondialdehyde, total protein, and creatinine in blood serum were measured. The histopathological and micrometric analysis of the hepatic and renal tissue sections were studied. The hepatosomatic index was raised significantly (0.098 ± 0.13 g) in Cr treated group. The blood serum level of AST (484 ± 10.7 U/L), ALT (163 ± 5.5 U/L), ALP (336.7 ± 9.5 U/L), MDA (642.3 ± 28.3 U/L), and creatinine (4.0 ± 0.1 mg/dL) were increased significantly, whereas total protein level was declined (2.8 ± 0.3 g/dL) significantly in Cr exposed group. In the histopathological study, necrosis, disturbed hepatic cords, impaired glomeruli, and Bowman's capsule were noted. Micrometric data from the liver and kidney revealed a significant surge in the size of hepatocytes and their nuclei (1188.2 ± 467.7 µ2 and 456.5 ± 205.6 µ2) and CSA of glomeruli and Bowman's capsule (9051.8 ± 249.8 µ2 and 11,835.5 ± 336.7 µ2) in Cr (VI) exposed group, whereas the brush border (10.2 ± 4.0 µ) size declined significantly. The administration of AV and AVNP reduced the oxidative stress induced by Cr (VI).","PeriodicalId":8917,"journal":{"name":"Biological Trace Element Research","volume":" ","pages":"5580-5595"},"PeriodicalIF":3.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140118680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluate the Work-Related Exposure of Vanadium on Scalp Hair Samples of Outdoor and Administrative Workers of Oil Drilling Field: Related Health Risks. 评估石油钻井领域户外和行政人员头皮毛发样本中与工作相关的钒暴露：相关的健康风险。

IF 3.4 3区生物学

Biological Trace Element Research Pub Date : 2024-12-01 Epub Date: 2024-02-20 DOI: 10.1007/s12011-024-04101-y

Anjum Lashari, Tasneem G Kazi, Hassan I Afridi, Jameel A Baig, Mohammad B Arain, Ayaz Ali Lashari

{"title":"Evaluate the Work-Related Exposure of Vanadium on Scalp Hair Samples of Outdoor and Administrative Workers of Oil Drilling Field: Related Health Risks.","authors":"Anjum Lashari, Tasneem G Kazi, Hassan I Afridi, Jameel A Baig, Mohammad B Arain, Ayaz Ali Lashari","doi":"10.1007/s12011-024-04101-y","DOIUrl":"10.1007/s12011-024-04101-y","url":null,"abstract":"Petrochemical facilities, including oil well drilling, are discharging resources of extensive noxious waste into the environment. The workers in different sections might be exposed to vanadium (V) through different routes (groundwater and soil), which is linked with extensive physiological disorders, hypertension, respiratory disorders, anemia, skin, and gastrointestinal disorders. This study determined the contents of V in a biological sample (scalp hair) of workers of different categories (outdoor and office workers) in an oil drilling field in Sindh, Pakistan. The environmental samples, groundwater, bottled mineral water, and soil samples were also analyzed for V. For comparative purposes, the scalp hair of age-matched male subjects residing in domestic areas of Hyderabad city, Pakistan, was also analyzed. Generally, the concentrations of V in groundwater near the oil drilling field and drilled soil illustrated significant variations. The results show that the vanadium concentration in the scalp hair of non-exposed referents (controls) and office workers (exposed referents) was 62% and 45% lower than those observed for outdoor drilling and cleaning mud workers. It was observed that high exposure to V in outdoor workers might be linked with different physiological disorders such as anemia, eye problems, and bronchial disorders.","PeriodicalId":8917,"journal":{"name":"Biological Trace Element Research","volume":" ","pages":"5366-5372"},"PeriodicalIF":3.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139904891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Determination of Toxic Elements in Cannabinoid and Opioid Drugs and Their Impact on Addicts' Health: A Comparative Study. 大麻类药物和阿片类药物中有毒元素的测定及其对吸毒者健康的影响：比较研究。

IF 3.4 3区生物学

Biological Trace Element Research Pub Date : 2024-12-01 Epub Date: 2024-02-22 DOI: 10.1007/s12011-024-04096-6

Ahsanullah Unar, Oan Muhammad Sahito, Laila Alsawalha, Hassan Imran Afridi, Farid Shokry Ataya, Muhammad Sohail Bashir, Dalia Fouad, Farah Naz Talpur, Naveed Ali

{"title":"Determination of Toxic Elements in Cannabinoid and Opioid Drugs and Their Impact on Addicts' Health: A Comparative Study.","authors":"Ahsanullah Unar, Oan Muhammad Sahito, Laila Alsawalha, Hassan Imran Afridi, Farid Shokry Ataya, Muhammad Sohail Bashir, Dalia Fouad, Farah Naz Talpur, Naveed Ali","doi":"10.1007/s12011-024-04096-6","DOIUrl":"10.1007/s12011-024-04096-6","url":null,"abstract":"Drug addiction is associated with significant health risks, including cardiovascular complications, cancer, and mental disorders. Illicit drugs, such as cannabinoids and opioids, including prescription medications, are widely consumed and have profound health consequences. Understanding the health effects of the toxic elements in these substances is critical for overdose prevention and effective recovery strategies. This study aimed to determine toxic elements, including arsenic (As), cadmium (Cd), mercury (Hg), and nickel (Ni), in cannabinoid and opioid drugs and in biological samples (whole blood, scalp hair, and serum) from 311 male drug abuse patients aged 15-60 years with a history of drug abuse. The participants were categorized into three age groups. The comparative analysis involved 113 reference subjects of the same age groups. The sample preparation employed microwave-assisted acid digestion, and the toxic elements were quantified using atomic absorption spectrophotometry. Accuracy was ensured using certified reference materials for hair, whole blood, and serum samples. Drug-addicted subjects had significantly higher concentrations of toxic elements (arsenic, cadmium, mercury, and nickel) in biological samples than referent subjects (p > 0.001). Elevated levels of these toxic elements may increase susceptibility to infections, possibly due to malnutrition, drug-related effects, and additional contaminants. These findings necessitate further studies to explore the long-term health outcomes, potential treatment options, and broader socioeconomic impacts of substance abuse. This study serves as a baseline for future research in this critical public health field.","PeriodicalId":8917,"journal":{"name":"Biological Trace Element Research","volume":" ","pages":"5339-5347"},"PeriodicalIF":3.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139929896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biochemical Markers of Zinc Nutrition. 锌营养的生化指标

IF 3.4 3区生物学

Biological Trace Element Research Pub Date : 2024-12-01 Epub Date: 2024-02-06 DOI: 10.1007/s12011-024-04091-x

Xinying Wang, Menghui Zhang, Jing Ma, Yanqing Tie, Shusong Wang

引用次数: 0

Effects of Zinc Compounds on the Enzymatic Activities of Lysozyme and Peroxidase and Their Antifungal Activities. 锌化合物对溶菌酶和过氧化物酶的酶活性及其抗真菌活性的影响

IF 3.4 3区生物学

Biological Trace Element Research Pub Date : 2024-12-01 Epub Date: 2024-02-20 DOI: 10.1007/s12011-024-04110-x

Yongdae Kim, Ji-Youn Chang, Yoon-Young Kim, Jae Wook Lee, Hong-Seop Kho

{"title":"Effects of Zinc Compounds on the Enzymatic Activities of Lysozyme and Peroxidase and Their Antifungal Activities.","authors":"Yongdae Kim, Ji-Youn Chang, Yoon-Young Kim, Jae Wook Lee, Hong-Seop Kho","doi":"10.1007/s12011-024-04110-x","DOIUrl":"10.1007/s12011-024-04110-x","url":null,"abstract":"This study aimed to investigate the effects of zinc compounds on the enzymatic activities of lysozyme, peroxidase, and the glucose oxidase-mediated peroxidase (GO-PO) system and their antifungal activities. Four different zinc compounds (zinc chloride, gluconate, lactate, and sulfate) were incubated with hen egg-white lysozyme (HEWL), bovine lactoperoxidase (bLPO), the GO-PO system, and human unstimulated whole saliva in solution and on a hydroxyapatite surface. Enzymatic activities of lysozyme, peroxidase, and the GO-PO system were measured through the hydrolysis of Micrococcus lysodeikticus, oxidation of fluorogenic 2',7'-dichlorofluorescin, and glucose assay, respectively. Interactions between zinc and enzymes were analyzed by surface plasmon resonance (SPR). The minimum inhibitory concentration (MIC) and candidacidal activities of zinc compounds were examined against three Candida albicans strains. Zinc gluconate and sulfate significantly increased the enzymatic activities of salivary lysozyme in the solution assay and of HEWL and salivary lysozyme on the hydroxyapatite surface. However, all examined zinc compounds significantly decreased the enzymatic activities of bLPO and salivary peroxidase in solution and on the surface. SPR analyses revealed binding of zinc to lysozyme and peroxidase, with affinity differing according to the zinc compounds. The MIC of zinc compounds against C. albicans was 1.0-2.4 mM. Candidacidal activities were 17.7-38.8% and 23.7-47.0% at 1.0 and 10 mM concentrations, respectively. In conclusion, zinc compounds enhanced lysozyme activity but inhibited peroxidase activity. Zinc compounds exhibited concentration-dependent candidacidal activity against C. albicans. Zinc compounds are potential therapeutic agents for oral health, especially for geriatric patients.","PeriodicalId":8917,"journal":{"name":"Biological Trace Element Research","volume":" ","pages":"5850-5862"},"PeriodicalIF":3.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11502591/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139904890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Maternal Fed Zinc-Deficient Diet: Effects on Relaxin Family Peptides and Oxidant System in the Testis and Liver Tissue of Male Offspring. 母体缺锌饮食：对雄性后代睾丸和肝组织中松弛素家族肽和氧化系统的影响

IF 3.4 3区生物学

Biological Trace Element Research Pub Date : 2024-12-01 Epub Date: 2024-02-26 DOI: 10.1007/s12011-024-04113-8

Hamiyet Kose, Abdullah Sivrikaya, Esma Menevse

{"title":"Maternal Fed Zinc-Deficient Diet: Effects on Relaxin Family Peptides and Oxidant System in the Testis and Liver Tissue of Male Offspring.","authors":"Hamiyet Kose, Abdullah Sivrikaya, Esma Menevse","doi":"10.1007/s12011-024-04113-8","DOIUrl":"10.1007/s12011-024-04113-8","url":null,"abstract":"Today, the studies are limited on roles of insulin-like peptide 3 (INSL3), insulin-like peptide 7 (INSL7), and relaxin family peptide receptor 1 (RXFP1) which are synthesized by the testis. It is aimed to investigate the levels of the sex hormone as testosterone and the family of insulin-like proteins (relaxin family peptides), which are important in the puberty transition, in the testicular and liver tissues of male offspring born to female rats fed a zinc-deficient diet during the pregnancy, and in the changes in lipid peroxidation markers. The study was performed on 40 male offspring. In Group I: Control group, both male offspring and mothers were fed with standard rat chow. In Group II: Zinc deficient diet, both male offspring and mothers were fed a zinc-deficient diet (2.8 mg/kg zinc). In Group III: Normal diet, male offspring fed standard rat chow for 45 days (66th day) after being separated from their mothers with a maternal zinc-deficient diet. In Group IV: Zinc-supplemented diet, offspring fed with zinc supplemented (5 mg/kg/day intraperitoneal zinc sulfate, i.p.) in addition to standard rat chow after being separated from their mothers with maternal zinc deficiency until the termination of the study (66th day). Our study suggests that zinc-supplemented diets play an important role in the changes in INSL3, INSL7, RXFP1, and testosterone levels during spermatogenesis. INSL7, INSL3, and RXFP1 levels were higher in zinc-supplemented group than the zinc-deficient diet group. Liver levels of INSL3, INSL7, and MDA were significantly different in zinc-deficiency diet group than zinc-supplemented group.","PeriodicalId":8917,"journal":{"name":"Biological Trace Element Research","volume":" ","pages":"5612-5623"},"PeriodicalIF":3.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11502584/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139970896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0