Biological Trace Element Research最新文献

{"title":"Serum Zinc-Alpha-2 Glycoprotein and Zinc Levels and Their Relationship with Insulin Resistance and Biochemical Parameters in Overweight and Obese Children.","authors":"Israel Martínez-Navarro, Jenny Vilchis-Gil, Patricia Elizabeth Cossío-Torres, Héctor Hernández-Mendoza, Miguel Klünder-Klünder, Esther Layseca-Espinosa, Othir Gidalti Galicia-Cruz, María Judith Rios-Lugo","doi":"10.1007/s12011-024-04480-2","DOIUrl":"https://doi.org/10.1007/s12011-024-04480-2","url":null,"abstract":"<p><p>The biological role of zinc-alpha 2-glycoprotein (ZAG) has been associated with lipid mobilization, although this is not entirely clear. The study's aim was to examine the serum levels of ZAG and zinc (Zn) and the Zn/ZAG in a population of children with overweight (OW) and obesity (OB), and their relationship with biochemical parameters. Our study was a cross-sectional analysis of a group of Mexican children aged 6-10 (n = 72). We analyzed anthropometric data and biochemical parameters, including fasting plasma glucose (FPG), high-density lipoprotein cholesterol (HDLc), low-density lipoprotein cholesterol (LDLc), triglycerides (TG), total cholesterol (TC), insulin, and homeostatic model assessment insulin resistance (HOMA-IR). ZAG protein levels were measured using enzyme-linked immunosorbent assay (ELISA), and serum zinc (Zn) levels were quantified using inductively coupled plasma mass spectrometry (ICP-MS). The Zn values indicate a statistically significant difference between normal weight (NW) and OW/OB children with Zn concentrations were 91 µg/dL for NW and 66 µg/dL for OW/OB children. ZAG values did not show significant differences between NW and OW/OB, and values were 2.1 mg/dL and 2.3 mg/dL, respectively. The Zn/ZAG ratio was lower in the OW/OB compared to the NW (p = 0.05). Correlations were found between FPG and Zn (p = 0.004) in NW boys, and ZAG (p = 0.046) in OW/OB boys, as well as a negative correlation between insulin and Zn in NW children of both sexes. HOMA-IR shows correlations between Zn (p = 0.008) in OW/OB boys, and ZAG (p = 0.010) in the OW/OB girls. Additionally, correlations were observed between LDLc, TG, and BMIz with Zn and ZAG in the boys. In the same way, we also found that girls with OW/OB had a Zn/ZAG ratio of - 2.32 (p = 0.043) compared to NW boys. In conclusion, our findings highlight the significant roles of Zn and ZAG in glucose and lipid metabolism. Furthermore, Zn/ZAG ratio may provide insights into nutritional deficiencies, adiposity, and metabolic health. However, further studies are necessary to validate our results.</p>","PeriodicalId":8917,"journal":{"name":"Biological Trace Element Research","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142862954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: 10-Hydroxy Decanoic Acid and Zinc Oxide Nanoparticles Retrieve Nrf2/HO-1 and Caspase-3/Bax/Bcl-2 Signaling in Lead-Induced Testicular Toxicity.","authors":"Adham M Maher, Ghidaa A Elsanosy, Doaa A Ghareeb, Samar S Elblehi, Samar R Saleh","doi":"10.1007/s12011-024-04491-z","DOIUrl":"https://doi.org/10.1007/s12011-024-04491-z","url":null,"abstract":"","PeriodicalId":8917,"journal":{"name":"Biological Trace Element Research","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142862952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Supranutritional Selenium Supplementation During Different Trimesters of Pregnancy on Humoral Immunity in Beef Cattle at Parturition.","authors":"Jean A Hall, Gerd Bobe, William R Vorachek, Joseph J Klopfenstein, Ian O Thompson, Cindy L Zurita Cruz, Brian P Dolan, Ling Jin, T Zane Davis","doi":"10.1007/s12011-024-04457-1","DOIUrl":"https://doi.org/10.1007/s12011-024-04457-1","url":null,"abstract":"<p><p>Supranutritional Se supplementation may improve immune responses in beef cattle. Immunity is compromised in beef cattle during the periparturient period. This study aims to determine the best time during pregnancy to supplement beef cows with Se-yeast to optimize humoral immunity at parturition. Multiparous, black Angus and Angus cross cows (n = 79) were used in the study. All cows had ad libitum access to a mineral supplement containing 120 mg/kg Se (US FDA regulations) from Na selenite. In addition, all cows except controls (CTR) received Se supplementation of 105 mg Se/week from Se-yeast boluses administered once weekly during their specific treatment trimester of gestation (TR1, TR2, or TR3) for 13 weeks. This dosage was supranutritional equaling 5 × the upper range of US FDA Se administration regulations. Blood was collected at parturition from all cows. Laboratory analyses studied to assess humoral immunity included measuring IBR, BVD types 1 and 2, PI3, and BRSV serum neutralization titers post vaccination, assessing total IgM and antigen-specific IgM concentrations, and determining complement-mediated bacterial killing percentages. Statistical analyses were performed using GraphPad Prism and SAS 9.4. Supranutritional Se-yeast supplementation increased whole-blood (WB) Se concentrations regardless of trimester of supplementation (all P < 0.0001). Supplementation during TR2 and TR3 was more effective in increasing WB-Se concentrations at parturition than during TR1 or CTR (all P < 0.0001). TR2 cows had higher serum neutralization titers for BRSV compared with CRT cows (P = 0.03). Total serum IgM and Vibrio coralliilyticus-specific IgM concentrations were highly correlated (r = 0.78; P < 0.0001). Compared with CTR cows, TR1, TR2, and TR3 cows had similar total IgM concentrations (all P ≥ 0.19) and similar Vibrio coralliilyticus-specific IgM concentrations (all P ≥ 0.47). Complement-mediated bacterial killing percentages were greater in TR2 and TR3 cows (> 99.6%) compared with TR1 (93.9%) and CTR (89.3%) cows, and all Se-supplemented TR groups were greater than CTR cows (all P ≤ 0.05). The significant group differences in the complement-mediated bacterial killing assay reflected WB-Se concentrations. Supranutritional Se-yeast supplementation during TR2 and TR3 is associated with higher serum neutralization titers for some viral antigens, as well as enhanced complement-mediated bacterial killing in cows at parturition. These findings suggest that Se supplementation during later trimesters of pregnancy may help combat infectious disease challenges during the periparturient period in beef cattle.</p>","PeriodicalId":8917,"journal":{"name":"Biological Trace Element Research","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142862953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"As, Cd, Hg, and Pb Biological Concentrations and Anthropometry in Slovak Adolescents.","authors":"Vlasta Masanova, Iveta Uhnakova, Sona Wimmerova, Tomas Trnovec, Eva Sovcikova, Henrieta Patayova, Lubica Palkovicova Murinova","doi":"10.1007/s12011-024-04484-y","DOIUrl":"https://doi.org/10.1007/s12011-024-04484-y","url":null,"abstract":"<p><p>Anthropometry provides a non-invasive technique for evaluating growth and obesity and serves as an indicator of health status. This cross-sectional study aims to investigate the association of internal arsenic (As), cadmium (Cd), total mercury (THg), methylmercury (MeHg), and lead (Pb) exposure with anthropometric parameters, including obesity, in adolescents. Participants (N = 320) were children aged 10-14 years (mean 11.8 years) from eastern Slovakia, at an early stage of adolescence characterized by growth acceleration. Metal concentrations in blood and urine were measured by ICP-MS (for As, Cd, and Pb), GC/ICP-MS (for MeHg) and amalgamation technique AAS (for THg). Median concentrations of the studied elements in whole blood (Cd: 0.16, Pb: 10.6, THg: 0.25, MeHg: 0.11 µg/L) and urine (Cd: 0.25, Pb: 0.73, As: 3.38 µg/g creatinine) were relatively low in our study group. The results showed that blood Cd and Pb concentrations were inversely associated with several anthropometric parameters (body weight, BMI, body fat percentage, chest circumference, and waist circumference) in both boys and girls. Conversely, blood THg concentration was positively associated with these parameters in boys. A positive relationship was also observed between blood MeHg concentration and height in boys, while negative associations between blood Cd and Pb concentrations and height were significant only in girls. No associations were found between metal concentrations (As, Cd, Pb) in urine and parameters of physical growth or obesity. This study demonstrates that even low-level exposure to Cd, Pb, and Hg can influence growth and obesity indicators in adolescents, with distinct sex-specific patterns, highlighting the need for ongoing monitoring and protection against environmental metal exposure.</p>","PeriodicalId":8917,"journal":{"name":"Biological Trace Element Research","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142852174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Arsenic Exposure on AS3MT Protein Levels in Serum of Type 2 Diabetic Patients Compared to Non-diabetics.","authors":"Saima Shokat, Riffat Iqbal, Muhammad Ahmed Ali, Atif Yaqub, Shaista Aslam, Samreen Riaz","doi":"10.1007/s12011-024-04448-2","DOIUrl":"https://doi.org/10.1007/s12011-024-04448-2","url":null,"abstract":"<p><p>This research explores the impact of arsenic exposure on serum protein profiles in type 2 diabetes patients, with an emphasis on the AS3MT protein as a biomarker. Utilizing Bradford protein assay, SDS-PAGE, HPLC, and mass spectrometry, we quantified and analyzed variations in serum protein levels, focusing on differences between control groups (82.94 ± 8.03 µg/mL) and diabetic patients (96.95 ± 5.02 µg/mL) of high arsenic exposed in areas Kasur and Lahore, Punjab, Pakistan. The study revealed a significant increase in total serum proteins and specifically identified elevated levels of AS3MT in the diabetic group compared to controls. By using 15% gel, proteins were separated, and bands were visible at 42KD. Further investigations using HPLC provided a detailed chromatographic profile of AS3MT, isolating this protein effectively and displaying its heightened abundance through a marked peak within the sample chromatograms. Additionally, intact mass and tryptic digestion profiles analyzed by mass spectrometry (molecular weight of 41,747.79 D) further corroborated the identity and modification of AS3MT in the context of arsenic exposure. ELISA was used for the quantification of AS3MT protein concentration, and a 260% increase was confirmed in the diabetic group exposed to arsenic. These findings suggested that arsenic exposure significantly alters AS3MT protein and serum protein levels in diabetic patients, supporting the hypothesis that AS3MT can serve as a biomarker for arsenic-induced diabetic conditions.</p>","PeriodicalId":8917,"journal":{"name":"Biological Trace Element Research","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142852181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hazard Analysis and Human Health Risk Assessment in the Mytilus Galloprovincialis and Rapana Venosa Species in the Black Sea's Türkiye Coastline by Multivariate Analysis.","authors":"Evrim Sibel Önel, Mustafa Türkmen, Erkan Kalıpcı","doi":"10.1007/s12011-024-04482-0","DOIUrl":"https://doi.org/10.1007/s12011-024-04482-0","url":null,"abstract":"<p><p>In this study; fourteen potentially toxic elements (PTEs) levels are measured in Mytilus galloprovincialis (MG) and in Rapana venosa (RV) intensively consumed in eight cities on the Black Sea coast of Türkiye. Additionally, human health risk levels from mollusks species consumption were assessed using multiple approaches and by Geographical Information Systems, spatial distribution map of PTEs of the region was prepared. The average PTEs levels in the two mollusks species are listed in the following order: Fe > Al > Zn > Cu > As > Mn > B > Cd > Se > Ni > Cr > Pb > Co > Hg with the levels of 114.8 > 79.7 > 39.49 > 9.75 > 5.74 > 3.22 > 2.97 > 2.74 > 0.72 > 0.40 > 0.24 > 0.22 > 0.11 > 0.015 µg g^-1 ww, respectively. The average concentration level of essential metals (Cu, Mn, Zn, Co and Fe) and toxic metals (Cr, Hg, Ni, Pb, Cd and As) was measured as 238.73 µg g^-1 ww in RV and 114.86 µg g^-1 ww in MG. The cities with the highest metal pollution index (MPI) levels were Rize, Samsun, Kastamonu and Sinop, respectively. The MPI values in mollusks soft tissue were 1.25 in MG and 2.51 in RV. For fourteen PTEs, the MPI from metal intake by ingesting two crustacea species were over than 1, indicating risk from consumption. In addition to this, since the THQ value of Cd and hazard index (HI) were determined above 1, it can be said that it does pose public health risk for RV.</p>","PeriodicalId":8917,"journal":{"name":"Biological Trace Element Research","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142845754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of the cGAS/STING Pathway in Arsenic-Induced Neurotoxicity: Insights from the Crosstalk Between Astrocytes and Neurons.","authors":"Daopeng Luo, Baofei Sun, Wenjuan Wang, Aihua Zhang","doi":"10.1007/s12011-024-04475-z","DOIUrl":"https://doi.org/10.1007/s12011-024-04475-z","url":null,"abstract":"<p><p>Arsenic is a detrimental environmental toxicant linked to neurological damage; however, the mechanisms involved remain incompletely understood. Chronic proinflammatory responses are thought to play a central role in arsenic-induced neurotoxicity. Astrocytes, which are the predominant glial cells in the central nervous system (CNS), release significant amounts of proinflammatory cytokines upon overactivation. However, the molecular mechanisms driving this response remain to be elucidated. This study aimed to elucidate the mechanisms underlying arsenic-induced astrocyte activation and the subsequent neuronal damage, both in vivo and in vitro. In a rat model of arsenic exposure, significant neuropathological damage was detected in the CA3 region of the hippocampus. Specifically, markers of astrocyte activation, such as glial fibrillary acidic protein (GFAP) and inducible nitric oxide synthase (iNOS), as well as the inflammatory cytokine interleukin (IL)-1β, were significantly upregulated, and apoptosis was markedly increased, indicating neurotoxic damage. Furthermore, in vitro experiments revealed that arsenic exposure induced substantial upregulation of cyclic GMP-AMP synthase (cGAS), stimulator of interferon genes (STING), GFAP, iNOS, and IL-1β in astrocytes, accompanied by an increase in IL-1β secretion into the culture supernatant. In addition, co-culturing neurons with conditioned medium from arsenic-exposed astrocytes resulted in significant neuronal apoptosis. Importantly, the cGAS-STING pathway inhibitor H-151 effectively suppressed the arsenic-induced astrocyte activation and IL-1β secretion, while also reducing neuronal apoptosis in the conditioned medium. Collectively, these results indicate that arsenic exposure activates the cGAS-STING signaling pathway in astrocytes, enhancing proinflammatory activation and IL-1β expression, which in turn mediates neuronal apoptosis, representing a critical mechanism underlying arsenic-induced neurotoxicity.</p>","PeriodicalId":8917,"journal":{"name":"Biological Trace Element Research","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142845755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Influence of Blood Titanium Levels on DNA Damage in Brazilian Workers Occupationally Exposed to Different Chemical Agents.","authors":"Angela M Moro, Natália Brucker, Gabriela Goethel, Ingrid Flesch, Sabrina Nascimento, Mariele Charão, Bruna Gauer, Elisa Sauer, Larissa V Cestonaro, Gabriel Pedroso Viçozzi, Adriana Gioda, Tatiana D Saint'Pierre, Marcelo D Arbo, Ingrid Garcia, Shanda A Cattani, Rodrigo R Petrecelli, Mirkos Ortiz Martins, Solange Cristina Garcia","doi":"10.1007/s12011-024-04472-2","DOIUrl":"https://doi.org/10.1007/s12011-024-04472-2","url":null,"abstract":"<p><p>Occupational exposure to pollutants may cause health-damaging effects in humans. Genotoxicity assays can be used to detect the toxic effects of pollutants. In the present study, we evaluated genetic damage in three populations occupationally exposed to benzene, pyrenes, and agrochemicals and assessed the possible influence of titanium (Ti) co-exposure. A total of 275 subjects were enrolled in this study. The occupationally exposed population was composed of 201 male individuals, divided into three different groups: gas station attendants (GSA group) (n = 76), taxi drivers (TD group) (n = 97), farmers (farmers group) (n = 28), and control (n = 74). Biomarkers of exposure and effect were investigated such as AChe, BuChE, t,t-muconic acid (t,t-MA), and 1-hydroxypyrene (1-OHP). Ti levels in blood were higher in all the workers compared with the control group. DNA damage evaluated by comet assay was higher in the taxi drivers and farmers than in the controls, and the frequency of micronucleate buccal cells was higher in the gas station attendants and taxi drivers than in the controls. Correlations were found among occupational exposure time and biomarkers of exposure, genotoxicity biomarkers, and blood Ti levels. Our results demonstrated Ti co-exposure in the gas station attendants, taxi drivers, and farmers, and blood Ti levels were linked with the respective biomarkers of exposure. Additionally, tools through machine learning corroborated these findings, and Ti was the factor that contributed to DNA damage. Thus, the present study indicates the role of Ti in occupational settings and interactions with already known major xenobiotics present in the occupational environment contributing to genotoxicity.</p>","PeriodicalId":8917,"journal":{"name":"Biological Trace Element Research","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142852264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Zinc Ameliorates Acrylamide-Induced Cognitive Impairment in Male Wistar Rats: Modulation of Oxidative Stress, Neuro-inflammation, and Neurotrophic Pathways.","authors":"Ayodeji Johnson Ajibare, Olabode Oluwadare Akintoye, Oluwatobiloba Adesewa Oriowo, Abraham Olufemi Asuku, Isaac Adeola Oriyomi, Abosede Mary Ayoola","doi":"10.1007/s12011-024-04490-0","DOIUrl":"https://doi.org/10.1007/s12011-024-04490-0","url":null,"abstract":"<p><p>This study investigated the neuromodulatory potential of zinc against acrylamide-induced cognitive impairment. Acrylamide (AA), a toxic substance commonly found in certain foods such as potato, grains and coffee, is known to cause neurological damage and severe cognitive decline. Twenty (20) male Wistar rats were divided into four groups (n = 5) by random selection. All groups except Control (Group 1) which received 1 mL/kg water daily, were induced with an oral dose of 10 mg/kg of Acrylamide. Acrylamide (AA) (Group 2) was left untreated, while Low Zinc (AA + LZN-Group 3) and High zinc (AA + HZN-Group 4) were orally treated respectively with 10 mg/kg and 30 mg/kg of Zinc for 8 weeks. Zinc treatment mitigated the anxiety-like behavior and spatial and non-spatial memory deficit which are all signs of cognitive impairment observed in the AA group. Zinc reverses the significant decrease in superoxide dismutase (SOD) and catalase, significant increase in malondialdehyde (MDA) and interleukin 1β (IL-1β) caused by AA demonstrating its antioxidant and anti-inflammatory properties. Zinc also demonstrated potency in up-regulating brain-derived neurotrophic factor (BDNF) gene expression and down-regulating acetylcholinesterase (AChE) expression. Zinc treatment at both doses significantly increased the number of dentate gyrus cells. This study demonstrates the ability of zinc to mitigate the cognitive impairment secondary to acrylamide exposure.</p>","PeriodicalId":8917,"journal":{"name":"Biological Trace Element Research","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142833840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Cytotoxicity and Genotoxicity of Copper oxide Nanoparticles in chickens.","authors":"Eman A Morsy, Ahmed M Hussien, Marwa A Ibrahim, Khaled Y Farroh, Eman I Hassanen","doi":"10.1007/s12011-024-04494-w","DOIUrl":"10.1007/s12011-024-04494-w","url":null,"abstract":"","PeriodicalId":8917,"journal":{"name":"Biological Trace Element Research","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142827240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}