Biomimetics最新文献

{"title":"Brain-Inspired Multisensory Learning: A Systematic Review of Neuroplasticity and Cognitive Outcomes in Adult Multicultural and Second Language Acquisition.","authors":"Evgenia Gkintoni, Stephanos P Vassilopoulos, Georgios Nikolaou","doi":"10.3390/biomimetics10060397","DOIUrl":"10.3390/biomimetics10060397","url":null,"abstract":"<p><strong>Background: </strong>Multicultural education and second-language acquisition engaged neural networks, supporting executive function, memory, and social cognition in adulthood, represent powerful forms of brain-inspired multisensory learning. The neuroeducational framework integrates neuroscience with pedagogical practice to understand how linguistically and culturally rich environments drive neuroplasticity and cognitive adaptation in adult learners.</p><p><strong>Objective: </strong>This systematic review synthesizes findings from 80 studies examining neuroplasticity and cognitive outcomes in adults undergoing multicultural and second-language acquisition, focusing on underlying neural mechanisms and educational effectiveness.</p><p><strong>Methods: </strong>The analysis included randomized controlled trials and longitudinal studies employing diverse neuroimaging techniques (fMRI, MEG, DTI) to assess structural and functional brain network changes. Interventions varied in terms of immersion intensity (ranging from limited classroom contact to complete environmental immersion), multimodal approaches (integrating visual, auditory, and kinesthetic elements), feedback mechanisms (immediate vs. delayed, social vs. automated), and learning contexts (formal instruction, naturalistic acquisition, and technology-enhanced environments). Outcomes encompassed cognitive domains (executive function, working memory, attention) and socio-emotional processes (empathy, cultural adaptation).</p><p><strong>Results: </strong>Strong evidence demonstrates that multicultural and second-language acquisition induce specific neuroplastic adaptations, including enhanced connectivity between language and executive networks, increased cortical thickness in frontal-temporal regions, and white matter reorganization supporting processing efficiency. These neural changes are correlated with significant improvements in working memory, attentional control, and cognitive flexibility. Immersion intensity, multimodal design features, learning context, and individual differences, including age and sociocultural background, moderate the effectiveness of interventions across adult populations.</p><p><strong>Conclusions: </strong>Adult multicultural and second-language acquisition represents a biologically aligned educational approach that leverages natural neuroplastic mechanisms to enhance cognitive resilience. Findings support the design of interventions that engage integrated neural networks through rich, culturally relevant environments, with significant implications for cognitive health across the adult lifespan and for evidence-based educational practice.</p>","PeriodicalId":8907,"journal":{"name":"Biomimetics","volume":"10 6","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12190708/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Three-Dimensional Stabilization Thread Design on Biomechanical Fixation and Osseointegration in Type IV Bone.","authors":"Nicholas J Iglesias, Vasudev Vivekanand Nayak, Arthur Castellano, Lukasz Witek, Bruno Martins de Souza, Edmara T P Bergamo, Ricky Almada, Blaire V Slavin, Estevam A Bonfante, Paulo G Coelho","doi":"10.3390/biomimetics10060395","DOIUrl":"10.3390/biomimetics10060395","url":null,"abstract":"<p><p>Achieving the appropriate primary stability for immediate or early loading in areas with low-density bone, such as the posterior maxilla, is challenging. A three-dimensional (3D) stabilization implant design featuring a tapered body with continuous cutting flutes along the length of the external thread form, with a combination of curved and linear geometric surfaces on the thread's crest, has the capacity to enhance early biomechanical and osseointegration outcomes compared to implants with traditional buttressed thread profiles. Commercially available implants with a buttress thread design (TP), and an experimental implant that incorporated the 3D stabilization trimmed-thread design (TP 3DS) were used in this study. Six osteotomies were surgically created in the ilium of adult sheep (N = 14). Osteotomy sites were randomized to receive either the TP or TP 3DS implant to reduce site bias. Subjects were allowed to heal for either 3 or 12 weeks (N = 7 sheep/time point), after which samples were collected en bloc (including the implants and surrounding bone) and implants were either subjected to bench-top biomechanical testing (e.g., lateral loading), histological/histomorphometric analysis, or nanoindentation testing. Both implant designs yielded high insertion torque (ITV ≥ 30 N⋅cm) and implant stability quotient (ISQ ≥ 70) values, indicative of high primary stability. Qualitative histomorphological analysis revealed that the TP 3DS group exhibited a continuous bone-implant interface along the threaded region, in contrast to the TP group at the early, 3-week, healing time point. Furthermore, TP 3DS's cutting flutes along the entire length of the implant permitted the distribution of autologous bone chips within the healing chambers. Histological evaluation at 12 weeks revealed an increase in woven bone containing a greater presence of lacunae within the healing chambers in both groups, consistent with an intramembranous-like healing pattern and absence of bone dieback. The TP 3DS macrogeometry yielded a ~66% increase in average lateral load during pushout testing at baseline (T = 0 weeks, <i>p</i> = 0.036) and significantly higher bone-to-implant contact (BIC) values at 3 weeks post-implantation (<i>p</i> = 0.006), relative to the traditional TP implant. In a low-density (Type IV) bone model, the TP 3DS implant demonstrated improved performance compared to the conventional TP, as evidenced by an increase in baseline lateral loading capacity and increased BIC during the early stages of osseointegration. These findings indicate that the modified implant configuration of the TP 3DS facilitates more favorable biomechanical integration and may promote more rapid and stable bone anchorage under compromised bone quality conditions. Therefore, such improvements could have important clinical implications for the success and longevity of dental implants placed in regions with low bone density.</p>","PeriodicalId":8907,"journal":{"name":"Biomimetics","volume":"10 6","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12190597/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Silanised Fluoride Hydrotalcites as Functional and Multicomponent Fillers for Dental Composites.","authors":"Morena Nocchetti, Michela Piccinini, Antonio Scafuri, Alessandro Di Michele, Valeria Ambrogi","doi":"10.3390/biomimetics10060398","DOIUrl":"10.3390/biomimetics10060398","url":null,"abstract":"<p><p>Acrylic resin composites with a high filler loading, consisting of a fluoride-containing hydrotalcite incorporated into silica nanoparticles, were prepared. The filler was obtained by a multi-step process. First, ZnAl hydrotalcite in fluoride form (HTlc/F) was functionalised with tetraethoxysilane to form Si-O-M bonds (M = Al or Zn) with the brucitic layers. The ethoxysilane groups exposed on the layers were used as nucleation seeds for silica nanoparticles. The composite, named SiO₂@HTlc/F, was then functionalised with 3-(trimethoxysilyl)-propyl methacrylate groups and used as a filler for acrylic resins. The methacrylate groups on the surface of the inorganic composite participated in the polymerisation process of the resin by minimising the phase separation between inorganic and polymer through the formation of chemical bonds at the polymer-inorganic interface. The filler in the resin increases the degree of polymerisation, bringing it to values very close to 100%. Finally, preliminary studies on the release of fluoride anions showed that they are released slowly over time.</p>","PeriodicalId":8907,"journal":{"name":"Biomimetics","volume":"10 6","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12190227/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144482998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a Cuttlefish-Inspired Amphibious Robot with Wave-Motion Propulsion and Rigid-Flexible Coupling.","authors":"Yichao Gao, Felix Pancheri, Tim C Lueth, Yilun Sun","doi":"10.3390/biomimetics10060396","DOIUrl":"10.3390/biomimetics10060396","url":null,"abstract":"<p><p>Amphibious robots require efficient locomotion strategies to enable smooth transitions between terrestrial and aquatic environments. Drawing inspiration from the undulatory movements of aquatic organisms such as cuttlefish and knifefish, this study introduces a bio-inspired propulsion system that emulates natural wave-based locomotion to improve adaptability and propulsion efficiency. A novel mechanism combining crank-rocker and sliding components is proposed to generate wave-like motions in robotic legs and fins, supporting both land crawling and aquatic paddling. By adopting a rigid-flexible coupling design, the system achieves a balance between structural integrity and motion flexibility. The effectiveness of the mechanism is systematically investigated through kinematic modeling, animation-based simulation, and experimental validation. The developed kinematic model captures the principles of wave propagation via the Crank-Slider-Rocker structure, offering insights into motion efficiency and thrust generation. Animation simulations are employed to visually validate the locomotion patterns and assess coordination across the mechanism. A functional prototype is fabricated and tested in both terrestrial and aquatic settings, demonstrating successful amphibious locomotion. The findings confirm the feasibility of the proposed design and underscore its potential in biomimetic robotics and amphibious exploration.</p>","PeriodicalId":8907,"journal":{"name":"Biomimetics","volume":"10 6","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12190592/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bio-Inspired Compliant Joints and Economic MPC Co-Design for Energy-Efficient, High-Speed Locomotion in Snake-like Robots.","authors":"Shuai Zhou, Gengbiao Chen, Mingyu Gong, Jing Liu, Peng Xu, Binshuo Liu, Nian Yin","doi":"10.3390/biomimetics10060389","DOIUrl":"10.3390/biomimetics10060389","url":null,"abstract":"<p><p>Snake-like robots face critical challenges in energy-efficient locomotion and smooth gait transitions, limiting their real-world deployment. This study introduces a bio-inspired compliant joint design integrated with a hierarchical neural oscillator network and an energy-optimized control framework. The joint mimics biological skeletal flexibility using specialized wheeled mechanisms and adaptive parallel linkages, while the control network enables adaptive gait generation and seamless transitions through a phase-smoothing algorithm. Critically, this work adopts a synergistic design philosophy where mechanical components and control parameters are co-optimized through shared dynamic modeling. The proposed predictive control strategy optimizes locomotion speed while minimizing energy consumption. Experimental simulations demonstrate that the method achieves an 18% higher average forward speed (0.0563 m/s vs. 0.0478 m/s) with 7% lower energy use (0.1952 J vs. 0.2107 J) compared to conventional approaches. Physical prototype testing confirms these improvements under real-world conditions, showing a 12.9% speed increase (0.0531 m/s vs. 0.0470 m/s) and 7.3% energy reduction (0.2147 J vs. 0.2317 J). By unifying mechanical flexibility and adaptive control parameter tuning, this work bridges dynamic performance and energy efficiency, offering a robust solution for unstructured environments.</p>","PeriodicalId":8907,"journal":{"name":"Biomimetics","volume":"10 6","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12191278/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radionuclide-Labeled Biomaterials: A Novel Strategy for Tumor-Targeted Therapy.","authors":"Shu Zhang, Aiyue Zhang, Xunhao Qi, Zongtai Han, Luqi Song, Jiayu Zhou, Guanglin Wang, Ran Zhu, Jianguo Li","doi":"10.3390/biomimetics10060394","DOIUrl":"10.3390/biomimetics10060394","url":null,"abstract":"<p><p>This paper presents a comprehensive review of recent advancements in radionuclide-labeled biomaterials for cancer therapy, with a particular focus on the characteristics, production methods, and labeling techniques of α-particle, β-particle, and Auger electron-based radiotherapy. It explores innovative strategies for targeted delivery systems and highlights the advantages of theranostics and combination therapies. The application of radionuclide-labeled biomaterials in various cancer types, including prostate cancer, breast cancer, neuroendocrine tumors, gliomas, and melanoma, is systematically summarized. Furthermore, the article critically examines current technological bottlenecks and challenges in clinical translation, while proposing future directions such as AI-assisted dose optimization and multimodal combination therapies. This review provides essential theoretical foundations and practical insights to facilitate the clinical translation of radionuclide-labeled biomaterials.</p>","PeriodicalId":8907,"journal":{"name":"Biomimetics","volume":"10 6","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12191312/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Enhanced Snow Geese Optimizer Integrating Multiple Strategies for Numerical Optimization.","authors":"Baoqi Zhao, Yu Fang, Tianyi Chen","doi":"10.3390/biomimetics10060388","DOIUrl":"10.3390/biomimetics10060388","url":null,"abstract":"<p><p>An enhanced snow geese algorithm (ESGA) is proposed to address the problems of the weakened population diversity and unbalanced search tendencies encountered by the snow geese algorithm (SGA) in the search process. First, an adaptive switching strategy is used to dynamically select the search strategy to balance the exploitation and exploration capabilities. Second, a dominant group guidance strategy is introduced to improve the population quality. Finally, a dominant stochastic difference search strategy is designed to enrich the population diversity and help it escape from the local optimum by co-directing effects in multiple directions. Ablation experiments were performed on the CEC2017 test set to illustrate the improvement mechanism and the degree of compatibility of their improved strategies. The proposed ESGA with a highly cited algorithm and the powerful improved algorithm are compared on the CEC2022 test suite, and the experimental results confirm that the ESGA outperforms the compared algorithms. Finally, the ability of the ESGA to solve complex problems is further highlighted by solving the robot path planning problem.</p>","PeriodicalId":8907,"journal":{"name":"Biomimetics","volume":"10 6","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12190386/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fluid-Structure Interaction Analysis of a Bionic Robotic Fish Based on a Macrofiber Composite Material.","authors":"Chenghong Zhang","doi":"10.3390/biomimetics10060393","DOIUrl":"10.3390/biomimetics10060393","url":null,"abstract":"<p><p>In this study, the power system of a bionic robotic fish has been significantly simplified, resulting in a reduced volume and enhanced flexibility of both the structure and movement. To comprehensively understand the dynamics, a fluid-structure interaction (FSI) analysis was conducted, considering the intricate interplay between the mollusk's structure and the surrounding fluid. This analysis took into account the dissipation due to fluid viscosity and the influence of the wake performance around the mollusk. The study examined the relationships between the driving frequency of the input signal and various parameters such as fluid pressure, propulsion force, and propulsion displacement of the soft robot fish head. With the robot fish's head fixed, the amplitude of propulsion motion and propulsion force were measured. The simulation results closely matched the experimental findings, indicating their potential to predict the propulsion characteristics of the soft robot fish in fluid environments and further improve its performance.</p>","PeriodicalId":8907,"journal":{"name":"Biomimetics","volume":"10 6","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12190201/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research on Motion Transfer Method from Human Arm to Bionic Robot Arm Based on PSO-RF Algorithm.","authors":"Yuanyuan Zheng, Hanqi Zhang, Gang Zheng, Yuanjian Hong, Zhonghua Wei, Peng Sun","doi":"10.3390/biomimetics10060392","DOIUrl":"10.3390/biomimetics10060392","url":null,"abstract":"<p><p>Although existing motion transfer methods for bionic robot arms are based on kinematic equivalence or simplified dynamic models, they frequently fail to tackle dynamic compliance and real-time adaptability in complex human-like motions. To address this shortcoming, this study presents a motion transfer method from the human arm to a bionic robot arm based on the hybrid PSO-RF (Particle Swarm Optimization-Random Forest) algorithm to improve joint space mapping accuracy and dynamic compliance. Initially, a high-precision optical motion capture (Mocap) system was utilized to record human arm trajectories, and Kalman filtering and a Rauch-Tung-Striebel (RTS) smoother were applied to reduce noise and phase lag. Subsequently, the joint angles of the human arm were computed through geometric vector analysis. Although geometric vector analysis offers an initial estimation of joint angles, its deterministic framework is subject to error accumulation caused by the occlusion of reflective markers and kinematic singularities. To surmount this limitation, this study designed five action sequences for the establishment of the training database for the PSO-RF model to predict joint angles when performing different actions. Ultimately, an experimental platform was built to validate the motion transfer method, and the experimental verification showed that the system attained high prediction accuracy (R² = 0.932 for the elbow joint angle) and real-time performance with a latency of 0.1097 s. This paper promotes compliant human-robot interaction by dealing with joint-level dynamic transfer challenges, presenting a framework for applications in intelligent manufacturing and rehabilitation robotics.</p>","PeriodicalId":8907,"journal":{"name":"Biomimetics","volume":"10 6","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12190595/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Teaching Bioinspired Design for Assistive Technologies Using Additive Manufacturing: A Collaborative Experience.","authors":"Maria Elizete Kunkel, Alexander Sauer, Carlos Isaacs, Thabata Alcântara Ferreira Ganga, Leonardo Henrique Fazan, Eduardo Keller Rorato","doi":"10.3390/biomimetics10060391","DOIUrl":"10.3390/biomimetics10060391","url":null,"abstract":"<p><p>Integrating bioinspired design and additive manufacturing into engineering education fosters innovation to meet the growing demand for accessible, personalized assistive technologies. This paper presents the outcomes of an international course, \"3D Prosthetics and Orthotics\", offered to undergraduate students in the Biomimetic program at Westfälische Hochschule (Germany), in collaboration with the 3D Orthotics and Prosthetics Laboratory at the Federal University of São Paulo-UNIFESP (Brazil). The course combined theoretical and hands-on modules covering digital modeling (CAD), simulation (CAE), and fabrication (CAM), enabling students to develop bioinspired assistive devices through a Project-based learning approach. Working in interdisciplinary teams, students addressed real-world rehabilitation challenges by translating biological mechanisms into engineered solutions using additive manufacturing. Resulting prototypes included a hand prosthesis based on the Fin Ray effect, a modular finger prosthesis inspired by tendon-muscle antagonism, and a cervical orthosis designed based on stingray morphology. Each device was digitally modeled, mechanically analyzed, and physically fabricated using open-source and low-cost methods. This initiative illustrates how biomimetic mechanisms and design can be integrated into education to generate functional outcomes and socially impactful health technologies. Grounded in the Mao3D open-source methodology, this experience demonstrates the value of combining nature-inspired principles, digital fabrication, Design Thinking, and international collaboration to advance inclusive, low-cost innovations in assistive technology.</p>","PeriodicalId":8907,"journal":{"name":"Biomimetics","volume":"10 6","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12190428/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}