Biofouling最新文献_第2页

Impact of hydrophobic and hydrophilic surface properties on Pseudomonas aeruginosa adhesion in materials used in mineral water wells. 疏水和亲水表面特性对矿泉水井所用材料中铜绿假单胞菌粘附性的影响。

IF 2.6 3区生物学

Biofouling Pub Date : 2024-10-08 DOI: 10.1080/08927014.2024.2410771

Danilo Vilas Boas, Clara M G Lima, Larissa P Margalho, Dionísio P Amorim-Neto, Héctor D S Canales, Wilson J F Lemos Junior, Ana Carolina Ramos, Giancarlo Saraiva, Anderson S Sant'Ana

{"title":"Impact of hydrophobic and hydrophilic surface properties on Pseudomonas aeruginosa adhesion in materials used in mineral water wells.","authors":"Danilo Vilas Boas, Clara M G Lima, Larissa P Margalho, Dionísio P Amorim-Neto, Héctor D S Canales, Wilson J F Lemos Junior, Ana Carolina Ramos, Giancarlo Saraiva, Anderson S Sant'Ana","doi":"10.1080/08927014.2024.2410771","DOIUrl":"https://doi.org/10.1080/08927014.2024.2410771","url":null,"abstract":"Microbiologically contaminated water is a significant source of infections in humans and animals, with Pseudomonas aeruginosa (PSA) being particularly concerning due to its ability to thrive in water environments and its resistance to many disinfectants. Therefore, this study investigates the adhesion potential of PSA strains on various materials used in mineral water extraction wells, focusing on hydrophobic and hydrophilic properties. Mineral water samples were collected from three wells (P-01, P-07, and P-08) within the Guarani Aquifer System and Fractured Aquifer System (SAF) in Brazil. The physicochemical properties of the water, including concentrations of Sr (strontium), Fe (iron), Si (silicon), SO42- (sulfate ions), Cl- (chloride ions), and ORP (oxidation-reduction potential), were analyzed. Results indicated higher PSA adhesion on hydrophobic materials, particularly high-density polyethylene (HDPE) and geomechanically plasticized polyvinyl chloride (PVC). Multiple correlation analyses revealed positive correlations between PSA adhesion on hydrophilic materials and Sr, Fe, Si, SO42-, and Cl- concentrations. Conversely, ORP negatively correlated with bacterial adhesion on PVC surfaces, suggesting higher ORP values reduced PSA attachment. These findings highlight the importance of water composition and material properties in influencing bacterial adhesion and potential biofilm formation in mineral water extraction systems.","PeriodicalId":8898,"journal":{"name":"Biofouling","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142387590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The microbial communities of the rust layer were influenced by seawater microbial communities. 锈层的微生物群落受到海水微生物群落的影响。

IF 2.6 3区生物学

Biofouling Pub Date : 2024-10-07 DOI: 10.1080/08927014.2024.2411076

Shengxun Yao, Junxiang Lai, Congtao Sun, Maomi Zhao, Jizhou Duan, Xiufen Liao, Zihan Pan

{"title":"The microbial communities of the rust layer were influenced by seawater microbial communities.","authors":"Shengxun Yao, Junxiang Lai, Congtao Sun, Maomi Zhao, Jizhou Duan, Xiufen Liao, Zihan Pan","doi":"10.1080/08927014.2024.2411076","DOIUrl":"https://doi.org/10.1080/08927014.2024.2411076","url":null,"abstract":"To reveal the responsible microorganisms of microbiologically-influenced-corrosion (MIC), using 16S rRNA and ITS sequencing techniques, we investigated the bacterial and fungal communities in rust layer and seawater. Results show that the corrosion-related genera of Erythrobacter, norank_f__Rhodothermaceae, and Acinetobacter bacteria, as well as Aspergillus fungi, were overrepresented in the rust layer, along with the Pseudoalteromonas and Marinobacterium bacteria in seawater, and Ramlibacter, Aquimarina, and Williamsia bacteria were first detected in the rust layer. SourceTracker analysis revealed that approximately 23.08% of bacteria and 21.48% of fungi originated from seawater. Stochastic processes governed the rust layer and seawater microbial communities, and network analysis showed coexistence and interaction among bacterial and fungal communities. These results indicate that the composition of microbial communities in the rust layer was influenced by the marine environmental microbial communities, which can provide basic data support for the control of MIC in marine-related projects.","PeriodicalId":8898,"journal":{"name":"Biofouling","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142380036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The arrangement of dual-species biofilms of Candida albicans and Issatchenkia orientalis can be modified by the medium: effect of Voriconazole. 培养基可改变白色念珠菌和东方 Issatchenkia 的双种生物膜的排列：伏立康唑的影响。

IF 2.6 3区生物学

Biofouling Pub Date : 2024-10-01 Epub Date: 2024-08-08 DOI: 10.1080/08927014.2024.2389848

Juliene Cristina da Silva Passos, Ana Beatriz Furtado Rodrigues, Carlos Alberto-Silva, Maricilia Silva Costa

{"title":"The arrangement of dual-species biofilms of Candida albicans and Issatchenkia orientalis can be modified by the medium: effect of Voriconazole.","authors":"Juliene Cristina da Silva Passos, Ana Beatriz Furtado Rodrigues, Carlos Alberto-Silva, Maricilia Silva Costa","doi":"10.1080/08927014.2024.2389848","DOIUrl":"10.1080/08927014.2024.2389848","url":null,"abstract":"Both Candida albicans and Issatchenkia orientalis have been isolated from different types of infections over the years. They have the ability to form communities of microorganisms known as biofilms. It has been demonstrated that the medium employed in studies may affect the biofilm development. The aim of this study was to investigate the arrangement of dual-species biofilms of C. albicans and I. orientalis cultivated on either RPMI-1640 or Sabouraud Dextrose Broth (SDB), as well as the inhibitory effect of Voriconazole (VRC). For the experiments performed, ATCC strains were used, and yeast-mixed suspensions were inoculated in 96-well plates with either RPMI-1640 or SDB, in the presence or absence of VRC. The results were observed by counting the number of CFU obtained from scraping off the biofilms produced and plating the content on CHROMagar Candida medium. It was observed that for all conditions tested the medium chosen affected the arrangement of dual-species biofilms: when RPMI-1640 was used, there was a prevalence of C. albicans, while the opposite was noted when SDB was used. It could be suggested that the medium and environment could regulate interactions between both yeast species, including the response to different antifungal drugs.","PeriodicalId":8898,"journal":{"name":"Biofouling","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141900856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genetic determinants of increased sodium hypochlorite and ciprofloxacin susceptibility in Pseudomonas aeruginosa PA14 biofilms. 铜绿假单胞菌 PA14 生物膜对次氯酸钠和环丙沙星敏感性增加的遗传决定因素。

IF 2.6 3区生物学

Biofouling Pub Date : 2024-10-01 Epub Date: 2024-08-27 DOI: 10.1080/08927014.2024.2395378

Waleska Stephanie da Cruz Nizer, Madison Elisabeth Adams, Megan Catherine Montgomery, Kira Noelle Allison, Carole Beaulieu, Joerg Overhage

{"title":"Genetic determinants of increased sodium hypochlorite and ciprofloxacin susceptibility in Pseudomonas aeruginosa PA14 biofilms.","authors":"Waleska Stephanie da Cruz Nizer, Madison Elisabeth Adams, Megan Catherine Montgomery, Kira Noelle Allison, Carole Beaulieu, Joerg Overhage","doi":"10.1080/08927014.2024.2395378","DOIUrl":"10.1080/08927014.2024.2395378","url":null,"abstract":"Reactive chlorine species (RCS) like sodium hypochlorite (NaOCl) are potent oxidizing agents and widely used biocides in surface disinfection, water treatment, and biofilm elimination. Moreover, RCS are also produced by the human immune system to kill invading pathogens. However, bacteria have developed mechanisms to survive the damage caused by RCS. Using the comprehensive Pseudomonas aeruginosa PA14 transposon mutant library in a genetic screen, we identified a total of 28 P. aeruginosa PA14 mutants whose biofilms showed increased susceptibility to NaOCl in comparison to PA14 WT biofilms. Of these, ten PA14 mutants with a disrupted apaH, PA0793, acsA, PA1506, PA1547, PA3728, yajC, queA, PA3869, or PA14_32840 gene presented a 4-fold increase in NaOCl susceptibility compared to wild-type biofilms. While none of these mutants showed a defect in biofilm formation or attenuated susceptibility of biofilms toward the oxidant hydrogen peroxide (H2O2), all but PA14_32840 also exhibited a 2-4-fold increase in susceptibility toward the antibiotic ciprofloxacin. Further analyses revealed attenuated levels of intracellular ROS and catalase activity only for the apaH and PA1547 mutant, providing insights into the oxidative stress response in P. aeruginosa biofilms. The findings of this paper highlight the complexity of biofilm resistance and the intricate interplay between different mechanisms to survive oxidative stress. Understanding resistance strategies adopted by biofilms is crucial for developing more effective ways to fight resistant bacteria, ultimately contributing to better management of bacterial growth and resistance in clinical and environmental settings.","PeriodicalId":8898,"journal":{"name":"Biofouling","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142071931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antibiotics stimulates the development of persistent cells in biofilms of Candida albicans bloodstream isolates. 抗生素会刺激血液中分离出的白色念珠菌生物膜中持久细胞的发展。

IF 2.6 3区生物学

Biofouling Pub Date : 2024-10-01 Epub Date: 2024-09-01 DOI: 10.1080/08927014.2024.2396013

Fernando Victor Monteiro Portela, Ana Raquel Colares de Andrade, Lívia Maria Galdino Pereira, Bruno Nascimento da Silva, Paulo Henrique Soares Peixoto, Bruno Rocha Amando, Nicole de Mello Fiallos, Pedro de Freitas Santos Manzi de Souza, Reginaldo Gonçalves de Lima-Neto, Glaucia Morgana de Melo Guedes, Débora Souza Collares Maia Castelo-Branco, Rossana de Aguiar Cordeiro

{"title":"Antibiotics stimulates the development of persistent cells in biofilms of Candida albicans bloodstream isolates.","authors":"Fernando Victor Monteiro Portela, Ana Raquel Colares de Andrade, Lívia Maria Galdino Pereira, Bruno Nascimento da Silva, Paulo Henrique Soares Peixoto, Bruno Rocha Amando, Nicole de Mello Fiallos, Pedro de Freitas Santos Manzi de Souza, Reginaldo Gonçalves de Lima-Neto, Glaucia Morgana de Melo Guedes, Débora Souza Collares Maia Castelo-Branco, Rossana de Aguiar Cordeiro","doi":"10.1080/08927014.2024.2396013","DOIUrl":"10.1080/08927014.2024.2396013","url":null,"abstract":"Candida albicans invasive candidiasis is considered a global health problem. In such cases, biofilm formation on implanted devices represents a therapeutic challenge and the presence of metabolically inactive persistent cells (PCs) in these communities increases their tolerance to fungicidal drugs. This study investigated the influence of amoxicillin, AMX; cefepime, CEF; gentamicin, GEN; amikacin, AMK; vancomycin, VAN; and ciprofloxacin, CIP; on the production of PCs in biofilms of C. albicans bloodstream isolates. 48 h-mature biofilms (n = 6) grown in RPMI-1640 supplemented with antibiotics were treated with 100 μg ml-1 amphotericin B and then evaluated for PCs. Biofilms grown in the presence of antibiotics produced more PCs, up to 10×, when exposed to AMX and CIP; 5 × to CEF; and 6 × to GEN and VAN. The results indicate that antibiotics can modulate PC production in C. albicans biofilms. This scenario may have clinical repercussions in immunocompromised patients under broad-spectrum antibiotic therapy.","PeriodicalId":8898,"journal":{"name":"Biofouling","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Interkingdom biofilm of Streptococcus pyogenes and Candida albicans: establishment of an in vitro model and dose-response validation of antimicrobials. 化脓性链球菌和白色念珠菌的界间生物膜：体外模型的建立和抗菌剂的剂量反应验证。

IF 2.6 3区生物学

Biofouling Pub Date : 2024-10-01 Epub Date: 2024-08-28 DOI: 10.1080/08927014.2024.2395390

Guilherme Dos Santos Gomes Alves, Amanda Munarolo Piacenza de Oliveira, Ana Carolyna Becher Roseno, Natália Pereira Ribeiro, Maria do Socorro Alves, Caio Sampaio, Rosana Leal do Prado, Juliano Pelim Pessan, Douglas Roberto Monteiro

{"title":"Interkingdom biofilm of Streptococcus pyogenes and Candida albicans: establishment of an in vitro model and dose-response validation of antimicrobials.","authors":"Guilherme Dos Santos Gomes Alves, Amanda Munarolo Piacenza de Oliveira, Ana Carolyna Becher Roseno, Natália Pereira Ribeiro, Maria do Socorro Alves, Caio Sampaio, Rosana Leal do Prado, Juliano Pelim Pessan, Douglas Roberto Monteiro","doi":"10.1080/08927014.2024.2395390","DOIUrl":"10.1080/08927014.2024.2395390","url":null,"abstract":"Although Streptococcus pyogenes and Candida albicans may colonize tonsillar tissues, the interaction between them in mixed biofilms has been poorly explored. This study established an interkingdom biofilm model of S. pyogenes and C. albicans and verified the dose-response validation of antimicrobials. Biofilms were formed on microplates, in the presence or absence of a conditioning layer of human saliva, using Brain Heart Infusion (BHI) broth or artificial saliva (AS) as a culture medium, and with variations in the microorganism inoculation sequence. Biofilms grown in AS showed higher mass than those grown in BHI broth, and an opposite trend was observed for metabolism. The number of S. pyogenes colonies was lower in AS. Amoxicillin and nystatin showed dose-dependent effects. The inoculation of the two species at the same time, without prior exposure to saliva, and using BHI broth would be the model of choice for future studies assessing the effects of antimicrobials on dual S. pyogenes/C. albicans biofilms.","PeriodicalId":8898,"journal":{"name":"Biofouling","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142078958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hydrodynamic frictional performance of fouled panels: a comparative study of different coating types. 结垢面板的水动力摩擦性能：不同涂层类型的比较研究。

IF 2.6 3区生物学

Biofouling Pub Date : 2024-10-01 DOI: 10.1080/08927014.2024.2404960

Irma Yeginbayeva, Aleksei Berdiuzhenko

{"title":"Hydrodynamic frictional performance of fouled panels: a comparative study of different coating types.","authors":"Irma Yeginbayeva, Aleksei Berdiuzhenko","doi":"10.1080/08927014.2024.2404960","DOIUrl":"https://doi.org/10.1080/08927014.2024.2404960","url":null,"abstract":"This research study delves into the hydrodynamic frictional characteristics of fouled panels coated with different types of coatings, investigating how fouling coverage and surface roughness influence drag. The investigation incorporates data on the overall percentage coverage of fouling, as well as roughness measurements obtained through a 3D profilometer. Drag data collected from a flowcell simulation of real-world flow conditions complements these measurements. Notably, the determination of the level of fouling leverages the capabilities of CIE L*a*b as an image analysis method, focusing on the overall coverage rather than individual fouling species. The objective is to illustrate how fouled panels perform under varying flow and coating conditions compared to their clean counterparts. Furthermore, the paper proposes a roughness scaling approach that considers both the percentage coverage and measured areal roughness for each coating type, encompassing both fouled and unfouled areas. This approach provides valuable insights into the combined effects of fouling and surface roughness on hydrodynamic performance, enhancing our understanding of the intricate interplay between these factors.","PeriodicalId":8898,"journal":{"name":"Biofouling","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142340562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characterization of methanogens from landfill samples: implications for sustainable biogas production. 垃圾填埋场样本中甲烷菌的特征：对可持续沼气生产的影响。

IF 2.6 3区生物学

Biofouling Pub Date : 2024-10-01 Epub Date: 2024-08-30 DOI: 10.1080/08927014.2024.2393841

Renjbar Muksy, Kamal Kolo

引用次数: 0

Durable photobioreactor antibiofouling coatings for microalgae cultivation by photoreactive poly(2,2,2-trifluoroethyl methacrylate). 光活性聚（2,2,2-三氟乙基甲基丙烯酸酯）用于微藻培养的耐用光生物反应器防污涂层。

IF 2.6 3区生物学

Biofouling Pub Date : 2024-10-01 Epub Date: 2024-08-30 DOI: 10.1080/08927014.2024.2391000

Honghe Song, Yuheng Jiang, Caixiang Chen, Shumei Wen, Zhenzhen Zhou, Chenghu Yan, Wei Cong

{"title":"Durable photobioreactor antibiofouling coatings for microalgae cultivation by photoreactive poly(2,2,2-trifluoroethyl methacrylate).","authors":"Honghe Song, Yuheng Jiang, Caixiang Chen, Shumei Wen, Zhenzhen Zhou, Chenghu Yan, Wei Cong","doi":"10.1080/08927014.2024.2391000","DOIUrl":"10.1080/08927014.2024.2391000","url":null,"abstract":"To improve the durability of the photobioreactor antibiofouling surface for microalgal cultivation, a series of photoreactive poly(2,2,2-trifluoroethyl methacrylate) (PTFEMA) were successfully synthesized and used to modify ethylene-vinyl acetate (EVA) films by a surface coating and UV light grafting method. Fourier transform infrared (FT-IR) spectra, X-ray photoelectron spectroscopy analysis (XPS) and fluorescence microscopy results indicated that PTFEMA were fixed successfully onto the EVA film surface through a covalent bond. During the microalgal adhesion assay, the number of EVA-PTFEMA film-adhered microalgae was 41.4% lower than that of the EVA film. Moreover, the number of microalgae attached to the EVA-PTFEMA film decreased by 61.7% after cleaning, while that of EVA film decreased by only 49.1%. It was found that the contact angle of EVA-PTFEMA film surface increased, and remained stable when immersed in acid and alkali solution for up to 90 days.HIGHLIGHTSDurable photobioreactor antibiofouling surfaces for microalgal cultivation were prepared successfully.The contact angle of antibiofouling coating surface remained stable in acid and base environment for 90 days.The attached microalgae on antibiofouling surface decreased 41.4% than those of unmodified surface.The attached microalgae on antibiofouling surface could be cleaned by 61.7% through changing the flow velocity of microalgal suspension.","PeriodicalId":8898,"journal":{"name":"Biofouling","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Amphotericin B and micafungin duo-loaded nanoemulsion as a potential strategy against Candida auris biofilms. 两性霉素 B 和米卡芬净双载纳米乳液作为一种潜在的抗念珠菌生物膜策略。

IF 2.6 3区生物学

Biofouling Pub Date : 2024-10-01 Epub Date: 2024-09-08 DOI: 10.1080/08927014.2024.2396020

Gabriel Davi Marena, André Luiz Carneiro Soares do Nascimento, Gabriela Corrêa Carvalho, Rafael Miguel Sábio, Tais Maria Bauab, Marlus Chorilli

{"title":"Amphotericin B and micafungin duo-loaded nanoemulsion as a potential strategy against Candida auris biofilms.","authors":"Gabriel Davi Marena, André Luiz Carneiro Soares do Nascimento, Gabriela Corrêa Carvalho, Rafael Miguel Sábio, Tais Maria Bauab, Marlus Chorilli","doi":"10.1080/08927014.2024.2396020","DOIUrl":"10.1080/08927014.2024.2396020","url":null,"abstract":"Candida auris is a multidrug-resistant yeast that has seen a worrying increase during the COVID-19 pandemic. Give7/n this, new therapeutic options, such as controlled-release nanomaterials, may be promising in combating the infection. Therefore, this study aimed to develop amphotericin B (AmB) and micafungin (MICA)-loaded nanoemulsions (NEMA) and evaluated against biofilms of C. auris. Nanoemulsions (NEs) were characterized and determined minimum inhibitory concentration MIC90, checkerboard and anti-biofilm. NEMA presented a size of 53.7 and 81.4 nm for DLS and NTA, respectively, with good stability and spherical morphology. MICAmB incorporated efficiency was 88.4 and 99.3%, respectively. The release results show that AmB and MICA obtained a release of 100 and 63.4%, respectively. MICAmB and NEMA showed MIC90 values of 0.015 and 0.031 ug/mL, respectively and synergism. NEMA showed greater metabolic inhibition and morphological changes in mature biofilms. This drugs combination and co-encapsulation proved to be a promising therapy against C. auris biofilms.","PeriodicalId":8898,"journal":{"name":"Biofouling","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142153108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0