Biochemical Systematics and Ecology最新文献

{"title":"Pharmaceutical potential of willow leaves in terms of salicylic alcohol content","authors":"Leonie Kayser ,&nbsp;Thomas Olaf Gruber ,&nbsp;Gregor Aas ,&nbsp;Guido Jürgenliemk","doi":"10.1016/j.bse.2025.105169","DOIUrl":"10.1016/j.bse.2025.105169","url":null,"abstract":"<div><div>Salicis cortex has analgesic, anti-inflammatory, antipyretic, and anti-rheumatic properties, primarily due to the content of salicylic alcohol derivatives (SAD) and other phenolic compounds<em>.</em> The Pharmacopoeia Europaea monographs willow bark and does not specify a particular species but requires a minimum content of 1.5 % SAD. This study aimed to determine whether the leaves of certain willow species could also be pharmaceutically relevant due to their SAD concentration, to identify species with high SAD levels, to figure out ideal harvest times, to investigate intraspecific variability, and to determine differences between the sexes in terms of SAD content, including less-studied species<em>.</em> Using a UPLC®-RP18-PDA method, 12 willow species with 42 individuals were analyzed. Concerning the average content of the entire observation period, the following species were identified as particularly SAD-rich (mean ± standard deviation): <em>S. purpurea</em> (6 ± 4 %), <em>S. aurita</em> (3 ± 4 %), <em>S. fragilis</em> (3.2 ± 2.3 %), <em>S. cinerea</em> (2.5 ± 3.0 %), and <em>S. lapponum</em> (1.7 ± 1.4 %). <em>S. daphnoides</em> (0.11 ± 0.20 %) and <em>S. caprea</em> (0.08 ± 0.21 %) are displayed as SAD-poor species. Statistical analysis revealed a slight intraspecific variation, but the interspecific variability of the SAD content was higher. The SAD values were significantly higher in mid- and late summer, except for <em>S. purpurea</em> (May) and <em>S. caesia</em> (June), as well as in 2019 compared to 2018. Moreover, no significant effect of sex could be detected. Considering the high costs of producing willow bark extracts, supplementing with willow leaves, particularly from SAD-rich species and genotypes, could be beneficial.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"124 ","pages":"Article 105169"},"PeriodicalIF":2.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145474194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First phytochemical study of the leaves and stem bark of Grewia brunnea K. Schum. (Malvaceae) and antiplasmodial evaluation of the isolated compounds","authors":"Klev Gaïtan Sikam ,&nbsp;Gervais Mouthé Happi ,&nbsp;Doriane Deutou Tégaboué ,&nbsp;Mohamed Foundikou Nsangou ,&nbsp;Céline Djama Mbazoa ,&nbsp;Jean Wandji ,&nbsp;Jean Duplex Wansi","doi":"10.1016/j.bse.2025.105155","DOIUrl":"10.1016/j.bse.2025.105155","url":null,"abstract":"<div><div>The first phytochemical investigation of the leaves and stem bark of <em>Grewia brunnea</em> K. Schum. led to the isolation and structural elucidation of twelve compounds, namely ursolic acid (<strong>1</strong>), rotundic acid (<strong>2</strong>), oleanolic acid (<strong>3</strong>), lupeol (<strong>4</strong>), 2<em>α</em>-hydroxylupeol (<strong>5</strong>), betulinic acid (<strong>6</strong>), lupenone (<strong>7</strong>), kaempferol (<strong>8</strong>), <em>β</em>-sitosterol (<strong>9</strong>), stigmastane-3,6-dione (<strong>10</strong>), stigmasterol (<strong>11</strong>), and stigmasterol-3-<em>O</em>-<em>β</em>-<span>d</span>-glucopyranoside (<strong>12</strong>). Among these, two compounds (<strong>2</strong> and <strong>5</strong>) are reported for the first time within the Malvaceae family, contributing valuable chemotaxonomic insight. Structural elucidation was accomplished using comprehensive spectroscopic techniques, including 1D and 2D NMR analyses, supported by chemical data and comparisons with literature references. Selected compounds (<strong>1</strong>, <strong>3</strong>–<strong>4</strong>, and <strong>6</strong>–<strong>8</strong>) were subsequently evaluated for their <em>in vitro</em> antiplasmodial activity against <em>Plasmodium falciparum</em> strains K1 and 3D7. Among the tested compounds, lupenone (<strong>7</strong>) exhibited strong inhibitory effect on both strains, with IC₅₀ values of 4.7 ± 0.6 μM (K1) and 5.7 ± 0.8 μM (3D7). Betulinic acid (<strong>6</strong>) and lupeol (<strong>4</strong>) also demonstrated notable activity against the 3D7 strain, with IC₅₀ values of 2.1 ± 0.3 μM and 4.3 ± 0.7 μM, respectively. In contrast, compounds <strong>1</strong>, <strong>3</strong>, and <strong>8</strong> showed only weak activity against the tested strains. These findings support the classification of <em>G. brunnea</em> within the <em>Grewia</em> genus and highlight its potential as a promising source of antiplasmodial lead compounds for future drug discovery.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"124 ","pages":"Article 105155"},"PeriodicalIF":2.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145333161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation between antibacterial activity and compound composition of Ardisia mamillata Hance extract","authors":"Lei Zeng ,&nbsp;Yingle Chen ,&nbsp;Wei Wei ,&nbsp;Song Wang ,&nbsp;Liu Yang ,&nbsp;Qiaoguang Li ,&nbsp;Zhihong Wang","doi":"10.1016/j.bse.2025.105142","DOIUrl":"10.1016/j.bse.2025.105142","url":null,"abstract":"<div><div>This study investigates the antibacterial potential of extracts from the two different varieties of <em>Ardisia mamillata Hance</em>, a plant known for its medicinal value and natural adaptation to damp, fungal-prone environments. Although widely appreciated for its ornamental and traditional therapeutic uses, its antimicrobial activity remains underexplored. Extracts were prepared from red-leaf (Am_red) and green-leaf (Am_green) variants and tested against two phytopathogenic fungi: <em>Fusarium</em> and <em>Botrytis cinerea</em>. Both variants exhibited antifungal activity, with Am_red extracts showing superior efficacy—achieving a 33.4 % higher average inhibition rate compared to Am_green. In particular, Am_red extracts demonstrated strong inhibition against <em>B. cinerea</em>, with an average inhibition rate of 87.23 %.</div><div>UPLC-MS/MS analysis revealed that the dominant chemical classes in both extract types were flavonoids, lipids, amino acids and derivatives, alkaloids, phenolic acids, and organic acids—comprising 86.32 % in Am_red and 85.56 % in Am_green. Several bioactive compounds were identified, including petunidin-3-O-glucoside, calycosin, hispidulin, vanillic acid, and syringic acid. The preliminary data suggests that flavonoids, phenolic acids, and alkaloids are the key contributors to the antibacterial properties observed. The findings highlight the potential of <em>A. mamillata Hance</em>, particularly its red-leaf form, as a source of natural antimicrobial agents for sustainable applications in plant protection and phytopathogen control.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"124 ","pages":"Article 105142"},"PeriodicalIF":2.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145155780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Secondary metabolites and biochemical adaptations of Scilla lakusicii and S. litardierei to karst environments: a metabolomic perspective","authors":"Biljana Kukavica ,&nbsp;Siniša Škondrić ,&nbsp;Uroš Gašić ,&nbsp;Dejan Stojković ,&nbsp;Filip Nikolić ,&nbsp;Tanja Trifković ,&nbsp;Đura Nakarada ,&nbsp;Miloš Mojović ,&nbsp;Danijela Mišić","doi":"10.1016/j.bse.2025.105123","DOIUrl":"10.1016/j.bse.2025.105123","url":null,"abstract":"<div><div>Comprehensive metabolomic analysis on the leaf extracts of <em>Scilla lakusicii</em> and <em>S. litardierei</em> revealed the presence of 175 secondary metabolites. The identified compounds were categorized into several groups based on their chemical structures: hydroxybenzoic acids, hydroxycinnamic acids, saponins, flavonoid glycosides, flavonoid aglycones, homoisoflavonoid glycosides, homoisoflavonoid aglycones, and other metabolites. Saponins were the most abundant in both species, with some detected for the first time in plant tissues. Regarding volatile compounds, extracts from both species contained α- and β-pinene, neophytadiene, and phytol. <em>S. litardierei</em> showed a higher capacity to neutralize DPPH radicals, while <em>S. lakusicii</em> was more effective in scavenging hydroxyl radicals and reducing Fe³⁺ and Cu²⁺ ions. Both species exhibited similar capacities for H₂O₂ removal and Fe chelation. In terms of anticandidal activity, <em>S. lakusicii</em> was particularly effective against <em>Candida glabrata</em> and resistant <em>C. auris</em>, the latter of which showed no response to the standard drug ketoconazole. <em>S. litardierei</em> was more effective against <em>C. glabrata</em>. Both extracts demonstrated significant efficacy against resistant <em>Escherichia coli</em> in terms of antibacterial activity, while <em>S. litardierei</em> proved more effective against resistant <em>Pseudomonas aeruginosa</em>. Overall, leaf extracts of both <em>Scilla</em> species displayed significant antioxidant and antimicrobial activity, attributable to their specific chemical composition. The richness of secondary metabolites and pronounced biological activity enable the adaptation of these <em>Scilla</em> species to karst environments.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"124 ","pages":"Article 105123"},"PeriodicalIF":2.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145004394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative analysis of volatile organic compounds and antioxidant activities in different organs of Lindera megaphylla Hemsl. (Lauraceae)","authors":"Liangyue Li ,&nbsp;Kaidiao Xu ,&nbsp;Liqiong Yang ,&nbsp;Yixin Wang ,&nbsp;Guangling Zhou ,&nbsp;Yao Li ,&nbsp;Huanhai Fan ,&nbsp;Jie Wu ,&nbsp;Hailong Qin ,&nbsp;Yahua Liu ,&nbsp;Jixin Li","doi":"10.1016/j.bse.2025.105164","DOIUrl":"10.1016/j.bse.2025.105164","url":null,"abstract":"<div><div>Intraspecific chemodiversity across plant organs reflects functional specialization in ecological adaptation. We investigated the organ-specific volatile profiles of <em>Lindera megaphylla</em> Hemsl. (Lauraceae), a keystone species in subtropical Asian forests, using GC–MS and multivariate analysis. Essential oils from fruits, leaves, and bark contained 94 volatile organic compounds, with sesquiterpene hydrocarbons dominating all organs (47.62 %–72.05 %). Notably, fruits exhibited a unique enrichment of aldehydes (29.96 %, primarily hexadecanal), contrasting with minimal levels (&lt;1.5 %) in leaves and bark. Multivariate analysis revealed significant chemodivergence, with <em>δ</em>-cadinene (abundant in bark) and copaene (abundant in fruits) as key discriminators. Antioxidant assays demonstrated a clear organ-specific and radical-specific functional correlate: fruit oil showed the strongest DPPH scavenging capacity (IC₅₀ = 3.75 mg/mL), whereas bark oil exhibited superior ABTS inhibition (IC₅₀ = 1.48 mg/mL). This study establishes the first organ-specific volatile profile of <em>L. megaphylla</em>, linking the divergent aldehyde and sesquiterpene chemistries to organ-dependent antioxidant efficacy. This intraspecific chemodiversity not only provides insights into ecological adaptation but also underscores the species' potential as a source of multiple, specialized natural products.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"124 ","pages":"Article 105164"},"PeriodicalIF":2.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145424693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unusual methionine-derived glucosinolates in Turritis glabra (Brassicaceae) include previously missing side chain lengths as well as 3-oxo and 3-hydroxy derivatives, characterized by NMR and tandem mass spectrometry","authors":"Azra Đulović ,&nbsp;Jianzhong Zhu ,&nbsp;Marcus A. Koch ,&nbsp;Mariela A.G. Ramírez ,&nbsp;David I. Pattison ,&nbsp;Dan Staerk ,&nbsp;Ivica Blažević ,&nbsp;Niels Agerbirk","doi":"10.1016/j.bse.2025.105150","DOIUrl":"10.1016/j.bse.2025.105150","url":null,"abstract":"<div><div>Several previously unreported glucosinolates (GSLs) were detected in rosette leaves of the Brassicaceous plant <em>Turritis glabra</em>. Four of them were isolated as desulfated derivatives. From MS/MS, NMR and UV of desulfoGSLs, four major <em>T. glabra</em> leaf GSLs were identified as 6-(methylsulfonyl)hexylGSL (<strong>78</strong>), 7-(methylsulfonyl)heptylGSL (<strong>160</strong>), 3-hydroxy-7-(methylsulfonyl)heptylGSL (<strong>161</strong>), and 6-(methylsulfonyl)-3-oxohexylGSL (<strong>162</strong>). The existence of intact <strong>78</strong>, <strong>160</strong>, <strong>161</strong> and <strong>162</strong> were supported by MS and demonstration of loss of hydrogen sulfate in MS/MS as well as sensitivity to <em>Sinapis alba</em> myrosinase. The identification of the position of the keto-group in <strong>162</strong> was challenging but confirmed by extensive 2D-NMR and MS of desulfo <strong>162</strong>. Attention was paid to equilibrium between a ring-closed and an open form of desulfo <strong>162</strong> due to the oxo group, an atypical UV spectrum, and observed semi-stable exchange of side chain hydrogens with deuterium from D₂O in the alpha-position relative to the oxo group, which were all in agreement with the structural conclusion. Tentative interpretation of the remaining GSL profile (investigated by LC-MS/MS of desulfated derivatives) suggests that <em>T. glabra</em> contains further yet undescribed but minor GSLs including 5-(methylsulfonyl)pentylGSL (<strong>[81]</strong>) as well as some previously known, structurally related GSLs. A reference seed accession of <em>T. glabra</em> allowing easy, permanent access to plants with this atypical GSL content, was characterized including DNA barcode confirmation of identity.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"124 ","pages":"Article 105150"},"PeriodicalIF":2.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145358907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chemotaxonomic profiling of Rubus sanctus populations from four Iraqi regions using GCMS","authors":"Bnar Khalid Bakr ,&nbsp;Mehdi Rahimi","doi":"10.1016/j.bse.2025.105176","DOIUrl":"10.1016/j.bse.2025.105176","url":null,"abstract":"<div><div><em>Rubus sanctus</em> Schreb., a medicinal shrub indigenous to the Kurdistan region of Iraq, has been utilized in traditional medicine for its anti-inflammatory, antimicrobial, and hepatoprotective properties. This study aims to provide a comprehensive chemotaxonomical profile of the leaf metabolome of Rubus sanctus, collected from four distinct locations (Kore, Balisan, Hiran, and Choman) utilizing GC-MS analysis to examine the impact of ecological variability on secondary metabolite composition. A total of 187 volatile and semi-volatile compounds were identified, including terpenoids, fatty acids, aromatic derivatives, and esters, many of which are linked to antioxidant and anti-inflammatory activities. Principal Component Analysis (PCA) and hierarchical clustering demonstrated notable chemical differentiation among populations, with Kore exhibiting the greatest diversity in terpenoid content, specifically squalene and neophytadiene. These findings are consistent with previous studies on related <strong><em>Rubus</em></strong> species, including <em>R. idaeus</em> and <strong><em>Crataegus azarolus</em></strong>, which identified sterolic compounds such as β-sitosterol and campesterol as associated with cardiovascular and metabolic advantages. The observed variation underscores the chemotaxonomic significance of secondary metabolites in differentiating closely related plant populations affected by environmental factors, including altitude and soil composition. This study incorporates ethnobotanical information from Safeen Mountain, highlighting the traditional use of <em>Rubus sanctus</em> in the treatment of liver and inflammatory conditions. The findings underscore the significance of location-specific research in pharmacognosy and establish a basis for subsequent bioactivity assays and the isolation of essential compounds. This study enhances the understanding of phytochemical diversity and therapeutic potential of underutilized medicinal plants in the Kurdistan region by integrating modern analytical techniques with indigenous knowledge.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"124 ","pages":"Article 105176"},"PeriodicalIF":2.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145525879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Constituents of Alchornea tiliifolia and their chemotaxonomic significance","authors":"Nguyen Huu Toan Phan,&nbsp;Nguyen Thi Thu Hien,&nbsp;Tran Thi Ngoc Hanh,&nbsp;Nguyen Huu Huong Duyen,&nbsp;Nguyen Thi Dieu Thuan,&nbsp;Pham Van Huyen","doi":"10.1016/j.bse.2025.105178","DOIUrl":"10.1016/j.bse.2025.105178","url":null,"abstract":"<div><div>Thirteen compounds (<strong>1</strong>–<strong>13</strong>) were isolated for the first time from the methanol extract of <em>Alchornea tiliifolia</em> (Benth.) Müll.Arg. leaves using various chromatographic techniques. These compounds include two flavonoids (<strong>1</strong>–<strong>2</strong>), two lignans (<strong>3</strong>–<strong>4</strong>), three benzoic acid derivatives (<strong>6</strong>–<strong>8</strong>), three triterpenoids (<strong>9</strong>–<strong>11</strong>), two sterols (<strong>12</strong>–<strong>13</strong>), and one phenylpropanoid (<strong>5</strong>). Notably, kaempferol 3-<em>O</em>-<em>β</em>-<span>d</span>-xylopyranoside (<strong>2</strong>), <em>β</em>-syringin (<strong>5</strong>), and lupenone (<strong>11</strong>) are reported for the first time in the genus <em>Alchornea</em>. The structures of the isolated compounds were elucidated based on NMR and MS spectral analyses, complemented by optical rotation measurements.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"124 ","pages":"Article 105178"},"PeriodicalIF":2.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145525880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phenolics, antioxidant potential, and enzyme inhibition capacity in leaf and flower of Hesperis thyrsoidea Boiss.","authors":"Nesrin Colak ,&nbsp;Nisa Turkan ,&nbsp;Faik Ahmet Ayaz ,&nbsp;Emrah Şi̇ri̇n","doi":"10.1016/j.bse.2025.105167","DOIUrl":"10.1016/j.bse.2025.105167","url":null,"abstract":"<div><div>Phenolic compounds are widely studied for their potential health benefits. However, their extraction efficiency, bioactive composition, and biological activities vary significantly depending on solvent selection and plant organ specificity. This study investigated the extraction efficiency, total phenolics and flavonoid contents, antioxidant capacity, phenolic acid and flavonoid profiles, and enzyme inhibitory activities of different extracts and fractions from the flowers and leaves of <em>Hesperis thyrsoidea</em> Boiss. (Brassicaceae). The extraction yield (%) varied depending on the solvents and plant organs, with crude extracts exhibiting the highest recovery, particularly in the flowers. Total phenolic and flavonoid contents were notably high in polyphenolic fractions, emphasizing the importance of selective fractionation in maximizing bioactive compound recovery. The antioxidant potential revealed that extracts of soluble free and glycoside-conjugated phenolic acid forms contributed significantly to the radical scavenging capacity. Twelve major flavonoids were detected in the samples, rutin being the most abundant in the leaves, while epicatechin and epicatechin-gallate were predominant in the flowers. The plant parts were rich in hydroxycinnamic acid derivatives, <em>m</em>-coumaric acid and sinapic acid exhibiting the highest concentrations in three distinct phenolic acid forms. Polyphenolic extracts exhibited particularly strong enzyme inhibitory activities for α-amylase, α-glucosidase, tyrosinase, acetylcholinesterase, and butyrylcholinesterase. These findings highlight the significance of solvent selection and fractionation techniques in optimizing phenolic compound extraction and bioactivity properties. The current results provide valuable insights concerning the development of functional foods, nutraceuticals, and pharmaceutical applications, reinforcing the potential use of <em>H. thyrsoidea</em> as a rich source of bioactive phenolics with strong antioxidant and enzyme inhibitory properties.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"124 ","pages":"Article 105167"},"PeriodicalIF":2.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145576313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chemical constituents from the fruits of Toxicodendron vernicifluum (Stokes) F. A. Barkley (Anacardiaceae) and their chemotaxonomic significance","authors":"Wenjing Zu ,&nbsp;Lu Guan ,&nbsp;Jie Liu ,&nbsp;Cai-Wen Meng ,&nbsp;Hongyun Bai ,&nbsp;MeiChen Li ,&nbsp;Jianyu Liu ,&nbsp;Yongnan Xu","doi":"10.1016/j.bse.2025.105146","DOIUrl":"10.1016/j.bse.2025.105146","url":null,"abstract":"<div><div>In the chemical investigation on the 75 % ethanol extract of the fruits of <em>Toxicodendron vernicifluum</em> (Stokes) F.A. Barkley (Anacardiaceae), a total of twenty compounds were isolated and identified by means of nuclear magnetic resonance (NMR) spectroscopy and comparison with literature data reported previously. These include eight flavonoids (<strong>1</strong>–<strong>8</strong>), two phenolic derivatives (<strong>9</strong>–<strong>10</strong>), five phenylpropanoid derivatives (<strong>11</strong>–<strong>15</strong>), three sesquiterpenes (<strong>16</strong>–<strong>18</strong>), and two lignans (<strong>19</strong>–<strong>20</strong>). Notably, compounds <strong>3</strong>, <strong>9</strong>, <strong>14</strong>, <strong>15</strong>, <strong>17</strong> and <strong>20</strong> were isolated from the genus <em>Toxicodendron</em> for the first time, whereas compounds <strong>1</strong>, <strong>7</strong>, <strong>10</strong>, <strong>12, 13, 16, 18,</strong> and <strong>19</strong> were isolated from the family Anacardiaceae for the first time. Based on previous phytochemical studies on <em>T. vernicifluum</em>, biflavonoids are presumably the constituents with relatively high content in its fruits. The chemotaxonomic significance of these isolates is also discussed.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"124 ","pages":"Article 105146"},"PeriodicalIF":2.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145262929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}