Biochemical Systematics and Ecology最新文献

{"title":"Insights into the evolution and taxonomic meaning of seed fatty acid profiles in Campomanesia (Myrtaceae)","authors":"Yacov Kilsztajn ,&nbsp;Leonardo Regnier de Lima Pereira ,&nbsp;Marcelo Tomé Kubo ,&nbsp;Antonio Salatino ,&nbsp;Maria Luiza Faria Salatino","doi":"10.1016/j.bse.2025.105148","DOIUrl":"10.1016/j.bse.2025.105148","url":null,"abstract":"<div><div>This study explores the composition, taxonomic significance, and evolutionary history of seed fatty acid (FA) profiles in <em>Campomanesia</em> (Myrtaceae), a South American genus comprising approximately 45 species. Seed oils from six <em>Campomanesia</em> species were analyzed using gas chromatography and mass spectrometry. FA-based clustering was then compared with molecular phylogeny derived from nuclear and plastid markers, with <em>Psidium guajava</em> and <em>Feijoa sellowiana</em> included as outgroups. The results revealed a high degree of congruence between FA composition and phylogenetic relationships, as well as species-specific FA profiles that were consistent across individuals from different populations, highlighting their potential as reliable taxonomic markers. While <em>P. guajava</em> and <em>F. sellowiana</em> exhibited high linoleic acid content, <em>Campomanesia</em> species presented more balanced proportions of saturated and monounsaturated FA. Ancestral state reconstructions indicated a consistent evolutionary trend toward reduced proportions of unsaturated FA within <em>Campomanesia</em>. Although correlations with climatic variables such as temperature and precipitation were weak and statistically non-significant, a strong phylogenetic signal was detected. These findings suggest that genetic drift, rather than climate-driven selection, may have played a dominant role in shaping FA profiles, reinforcing their potential utility in taxonomic studies of the genus.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"124 ","pages":"Article 105148"},"PeriodicalIF":2.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145217442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative study of Juniperus turbinata (Cupressaceae) cone and leaf based on GC-MS-Ms analysis and biological proprieties","authors":"Mehdi Boumediene ,&nbsp;Asmae Saih ,&nbsp;Jihane Touhtouhe ,&nbsp;Mohamed Akhazzane ,&nbsp;Taoufiq Benali ,&nbsp;Abdelhakim Bouyahya ,&nbsp;Fatima Lakhdar ,&nbsp;Gokhan Zengin ,&nbsp;Khalil Hammani ,&nbsp;Nargis Sahib","doi":"10.1016/j.bse.2025.105166","DOIUrl":"10.1016/j.bse.2025.105166","url":null,"abstract":"<div><div>Essential oils (EOs) extracted from leaves (JTEO_L) and cones (JTEO_C) of <em>Juniperus turbinata</em> leaves were analysed to determine their chemical composition and studied <em>in vitro</em> their antioxidant, antidiabetic, dermatoprotective, and neuroprotective effects. The results of GC-MS-MS characterization revealed significant qualitative and quantitative differences in volatile profiles between the two parts of the plant. JTEO_C was dominated by α-pinene (81 %), followed by limonene (2.38 %), <em>trans</em>-verbenol (2.37 %), and <em>α</em>-terpinyl acetate (1.8 %), while JTEO_L contained <em>α</em>-pinene (20.71 %), <em>α</em>-terpinyl acetate (19.87 %), and <em>β</em>-phellandrene (15.56 %) as major components. The antioxidant assays showed varying activities, with JTEO_L showing superior radical scavenging capacity in DPPH and ABTS assays with 9.33 ± 0.55 mg TE/g and 41.16 ± 0.97 mg TE/g, respectively, while JTEO_C exhibited higher reducing power in CUPRAC and FRAP assays as 85.69 ± 1.35 mg TE/g 47.78 ± 0.27 mg TE/g, respectively. In enzyme inhibition assays, both EOs showed significant <em>α</em>-amylase inhibition (JTEO_C: 1.380 ± 0.019 mmol ACAE/g; JTEO_L: 1.084 ± 0.055 mmol ACAE/g) but no <em>α</em>-glucosidase activity. JTEO_L demonstrated superior tyrosinase inhibition (68.07 ± 3.74 mg KAE/g) compared to cone EO (17.14 ± 4.27 mg KAE/g). In cholinesterase inhibition assays, JTEO_C specifically inhibited acetylcholinesterase (7.25 ± 0.16 mg GALAE/g), while both EOs showed butyrylcholinesterase inhibition, with JTEO_L being more potent (2.85 ± 0.64 mg GALAE/g versus 1.52 ± 0.32 mg GALAE/g). Our current study suggests that <em>J. turbinata</em> EOs, particularly from leaves, possess a promising potential for applications in antioxidant, dermatoprotective, and neuroprotective treatments.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"124 ","pages":"Article 105166"},"PeriodicalIF":2.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145474193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of allelopathic plant extracts on Leucaena leucocephala (Lam.) de Wit seeds: a multivariate and machine learning approach to a global problem","authors":"Erika Elias da Silva,&nbsp;Luan Danilo Ferreira de Andrade Melo,&nbsp;João Luciano de Andrade Melo Junior,&nbsp;Larice Bruna Ferreira Soares,&nbsp;Vilma Marques Ferreira,&nbsp;Keven Willian Sarmento Galdino da Silva,&nbsp;Marcus Gabriel de Carvalho Ramos","doi":"10.1016/j.bse.2025.105137","DOIUrl":"10.1016/j.bse.2025.105137","url":null,"abstract":"<div><div>The invasive species <em>Leucaena leucocephala</em> (leucaena) negatively impacts ecosystems, requiring sustainable control strategies. This study evaluated the allelopathic effects of plant extracts from <em>Eucalyptus staigeriana</em>, <em>Corymbia citriodora</em>, <em>Eucalyptus globulus</em>, <em>Schinus terebinthifolius</em>, <em>Copaifera officinalis</em>, and pyroligneous extract on the germination and early development of <em>L. leucocephala</em>. Essential oils were tested at concentrations of 0.2; 0.4; 0.6; 0.8; 1.0 and 1.2 % (v v⁻¹), while the pyroligneous extract was diluted at 1:100 (v v⁻¹), using the same concentrations of essential oils, with the control (0 %), immersed in distilled water, only. Germination and morphological parameters were analyzed using principal component analysis. All extracts inhibited leucaena germination and growth, with efficiency dependent on concentration. The essential oils of <em>E. staigeriana</em> and <em>C. citriodora</em> were most effective at 1.2 %, while <em>E. globulus</em> performed best at 0.8 and 1.0 %. <em>S. terebinthifolius</em> significantly inhibited germination at all concentrations, whereas <em>C. officinalis</em> essential oil and pyroligneous extract showed optimal results at 1.0 and 1.2 %. The study confirms that plant extracts are viable bioherbicides for controlling <em>L. leucocephala</em>.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"124 ","pages":"Article 105137"},"PeriodicalIF":2.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145106552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A new norlignan and other compounds from Artemisia frigida Willd","authors":"Xin-Ya Dong ,&nbsp;Ru-Ya Li ,&nbsp;Hong-Xia Tang ,&nbsp;Ya-Jie Li ,&nbsp;Jun Chen ,&nbsp;Jin-Guo Luo ,&nbsp;Na Yu ,&nbsp;Xiang-Wei Xu ,&nbsp;Xu-Dong Zhou","doi":"10.1016/j.bse.2025.105102","DOIUrl":"10.1016/j.bse.2025.105102","url":null,"abstract":"<div><div><em>Artemisia frigida</em> is an endemic plant that only grows in China and its phytochemistry has never been fully appreciated and sufficiently studied. In the present study, a phytochemical investigation on the aerial parts of <em>A</em>. <em>frigida</em> resulted in the isolation of a new norlignan (<strong>1</strong>), together with twelve known constituents (<strong>2</strong>–<strong>13</strong>). Their structures were established by NMR spectroscopic analysis and comparison of their data with previous literature. Compound <strong>1</strong> existed as racemic mixtures, and all of the compounds were isolated from <em>A. frigida</em> for the first time except compounds <strong>2</strong>–<strong>5</strong>. Moreover, the chemotaxonomic significance corresponding to the above compounds was investigated.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"123 ","pages":"Article 105102"},"PeriodicalIF":2.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144772208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metabolite profiling and cytotoxicity of Tragopogon dubius fractions against MCF-7 cells","authors":"Sheikh Showkat Ahmad,&nbsp;Chandnig Garg,&nbsp;Satwinderjeet Kaur","doi":"10.1016/j.bse.2025.105065","DOIUrl":"10.1016/j.bse.2025.105065","url":null,"abstract":"<div><div><em>Tragopogon dubius</em> is a biennial herbaceous plant with multiple uses in ethnomedicine. Traditionally consumed as a vegetable, it has been reported to treat various conditions, including wounds, liver dysfunction, kidney disorders, and certain skin diseases. Despite its traditional use, it remains one of the least explored species in terms of biological activity. This study aimed to evaluate the antigenotoxic, antioxidant, and antiproliferative properties of the ethyl acetate extract obtained from the stem and leaves of <em>T. dubius</em> (TrDE), along with eleven fractions (F-1 to F-11) isolated via preparative thin-layer chromatography. Phytochemical profiling was performed using High-Resolution Liquid Chromatography-Mass Spectrometry (HRLC-MS/QTOF/Orbitrap) and Gas Chromatography-Mass Spectrometry (GC-MS). Among the isolated fractions, F-9, F-10, and F-11 showed the highest antioxidant activity at a concentration of 800 μg/mL, as determined by DPPH (IC₅₀ 44.70, 19.90, and 25.35 μg/mL), ABTS (IC₅₀ 64.53, 22.64, and 34.28 μg/mL), and FRAP (IC₅₀ 37.92, 23.85, and 57.96 μg/mL) assays. The F-11 fraction also exhibited the highest total phenolic content (70.00 ± 1.10 mg GAE/g dw), followed by F-10 and F-9, all exceeding the crude extract (33.04 ± 1.10 mg GAE/g dw). Additionally, the TrDE extract displayed genoprotective effects against hydrogen peroxide (H₂O₂)-induced DNA damage in human lymphocytes. In antiproliferative assays, the fractions demonstrated significant cytotoxicity against MCF-7 breast cancer cells in a dose-dependent manner. Notably, fractions F-7, F-10, and F-11 exhibited the highest cytotoxic effects, with GI₅₀ values of 20.14, 35.37, and 33.58 μg/mL, respectively. These findings suggest that <em>T. dubius</em> fractions possess promising therapeutic potential against human breast cancer (MCF-7), warranting further in vivo investigation.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"123 ","pages":"Article 105065"},"PeriodicalIF":1.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144307542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biochemical analysis of petals in Rosa species (Rosaceae) from Iran using gas chromatography-mass spectrometry","authors":"Sareh Seyedipour,&nbsp;Kazem Mahdigholi,&nbsp;Vahid Niknam","doi":"10.1016/j.bse.2025.105056","DOIUrl":"10.1016/j.bse.2025.105056","url":null,"abstract":"<div><div>This study investigates the phytochemical composition, with a focus on alkane profiles, of petals from eight <em>Rosa</em> species native to Iran using gas chromatography–mass spectrometry (GC-MS). Flowers were collected from healthy individuals in wild populations across diverse regions of Iran, including the Alborz mountain range, at altitudes between 1546 and 2597 m. The dried petals were extracted using the Bligh and Dyer method and analyzed with GC-MS under standardized chromatographic conditions. The analysis revealed 81 distinct phytochemical compounds across the studied species, including a range of alkanes. Identified compounds included 32 alkanes, 4 triterpenoids, 4 phytosterols/steroids, 3 fatty acid methyl esters, 3 phenols, 2 phthalate esters, 2 alkenes, 1 oxaspiro compound, and other minor constituents such as alkylbenzenes, benzoate esters, and vitamin E. Alkane chain lengths ranged from C₁₂ to C₄₄, with interspecific variation in both diversity and abundance. Multivariate statistical analyses, including cluster analysis (UPGMA), Pearson correlation, and principal component analysis (PCA), were applied to assess interspecific chemical variation and species relationships. Pearson correlation analysis revealed strong positive associations between species such as <em>R. beggeriana</em> and <em>R. iberica</em> (p &lt; 0.001), as well as among specific alkane compounds (r &gt; 0.92, p &lt; 0.0001), suggesting shared biosynthetic pathways. A significant finding of this study is the first report of 7,9-di-<em>tert</em>-butyl-1-oxaspiro[4.5]deca-6,9-diene-2,8-dione in <em>Rosa</em> petals. These results enhance the chemotaxonomy of the <em>Rosa</em> genus and suggest potential therapeutic and nutritional uses for wild <em>Rosa</em> species.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"123 ","pages":"Article 105056"},"PeriodicalIF":1.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144243433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Volatile oil content and composition in fresh and dried Lavandula species: The impact of distillation time","authors":"Emir Soltanbeigi ,&nbsp;Hasan Maral","doi":"10.1016/j.bse.2025.105066","DOIUrl":"10.1016/j.bse.2025.105066","url":null,"abstract":"<div><div>A wide range of biotic and abiotic factors influence both the yield and quality of essential oils (EOs). Among post-harvest processes, distillation time (DT) plays a pivotal role in shaping the EO yield and its chemical composition. This study investigates the effects of DT on the EO yield and volatile compound profiles of lavender (<em>Lavandula angustifolia</em> L.) and lavandin (<em>Lavandula</em> × <em>intermedia</em> L.) obtained from fresh and dried stemless flowers. To this end, five different distillation durations were assessed: 1, 2, 3, 4, and 5 h. In general, EO yield increased progressively with extended DTs. The maximum EO yield in fresh and dried lavender was obtained at 3 h (3.25 %) and 5 h (7.6 %) of distillation, respectively. Similarly, the highest EO yields in fresh and dried lavandin flowers were recorded at 3 h (3.2 %) and 4 h (7.2 %) of distillation, respectively. Notably, fresh floral material yielded proportionally higher EO content in both species. GC/FID-MS analysis revealed linalool (39.80–52.75 %) as the dominant compound across all samples. Other major constituents in lavender included linalyl acetate (16.74–23.10 %), terpinen-4-ol (5.24–6.79 %), and lavandulyl acetate (2.37–3.60 %). In lavandin, the principal compounds were camphor (10.93–12.99 %), 4-terpineol (7.60–8.23 %), borneol (6.77–7.52 %), 1,8-cineole (5.39–6.03 %), and linalyl acetate (2.21–3.83 %). Extended distillation time enhances essential oil yield and alters the chemical profile, particularly increasing the proportion of key compounds like linalool and camphor. For optimal yield and market-aligned composition, a DT of 3–5 h is recommended depending on flower condition and species.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"123 ","pages":"Article 105066"},"PeriodicalIF":1.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144289018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biocontrol potential of metabolites from Streptomyces sp., non-toxic Aspergillus fumigatus, and their co-cultures against tomato anthracnose","authors":"Tavga Sulaiman Rashid ,&nbsp;Hayman Kakakhan Awla ,&nbsp;Rouhallah Sharifi","doi":"10.1016/j.bse.2025.105067","DOIUrl":"10.1016/j.bse.2025.105067","url":null,"abstract":"<div><div>The biological activity of <em>Streptomyces</em> sp. and <strong>non-toxic</strong> <em>Aspergillus fumigatus</em>, along with their metabolites in mono and co-culture, was tested against <em>Colletotrichum acutatum</em>. Additionally, the presence of volatile metabolites was observed using gas chromatography-mass spectrometry (GC-MS). The tomato plants were treated with both <em>Streptomyces</em> sp. and <em>A. fumigatus</em> separately and in combination for <em>in vivo</em> test. Both <em>Streptomyces</em> sp. and <em>A. fumigatus</em> exhibited antifungal activity against <em>C. acutatum</em>. In co-cultivation, metabolites demonstrated 100 % inhibition of the pathogenic fungus. According to GC-MS analysis, 35 compounds were identified from <em>A. fumigatus</em>, and 21 from <em>Streptomyces</em> sp. Co-cultivation of <em>A. fumigatus</em> and <em>Streptomyces</em> sp. induced the biosynthesis of 21 compounds. Most of volatile compounds present at high percentages in co-culture were not detected in the monoculture of each microorganism. The top volatiles in co-culture included acetic acid (25.58 %), furfural (9.89 %), Levulinic acid, methyl ester (7.22 %), dimethadione (6.50 %), benzene acetic acid (6.03 %), and levulinic acid (5.93 %). Significant improvements in shoot height, root length, shoot and root dry weight and the anthracnose disease reduction were observed mainly with the combination of <em>Streptomyces</em> sp. and <em>A. fumigatus</em>. These outcomes support the use of the co-cultivation technique as a viable approach for acquiring beneficial metabolites from microorganisms.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"123 ","pages":"Article 105067"},"PeriodicalIF":1.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144290542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of habitat and herbivory stress on essential oil yield in Cinnamomum longipaniculatum","authors":"Xin-Min Liu ,&nbsp;Ying-zhou Chen ,&nbsp;Qin Liu ,&nbsp;Qiong-zhi Hu ,&nbsp;Ya Tang","doi":"10.1016/j.bse.2025.105091","DOIUrl":"10.1016/j.bse.2025.105091","url":null,"abstract":"<div><div>Leaf of <em>Cinnamomum longipaniculatum</em> contains around 60 % essential oil (EO) being 1,8-cineole the main component. This is the biggest EO producing tree species in China and Sichuan of China has a plantation of 36 000 ha. Despite many studies, EO content of very young leaves and its variation of a full year is understudied and the effects of different habitats and insect herbivore on EO yield is poorly understood. A 12-month long, half-month interval monitoring of leaf EO content in an industrial farm revealed an EO content ranging from 2.06 % to 4.25 %. Half-monthly EO content varied from 1.76 % in early March to 2.75 % in early September in fresh leaves, and from 2.55 % in late October to 4.13 % in early April in dry leaves. Leaf EO content was significantly higher in dry than in fresh (3 % versus 2.03 %), two-year old than one-year old (3.06–4.25 % versus 2.06–3.22 %) leaves. EO content differed significantly on different slope aspects (3.87 % on southwest, 3.52 % on southeast, 3.26 % on east, and 2.85 % on northwest), and on different slope gradients (2.99 % on 0–10° slopes, 3.27 % on 10–20° slopes, 3.80 % on 20–30° slopes). Insect herbivore significantly increased EO content and it was 2.91–3.63 % in damaged versus 2.06–3.22 %) in undamaged leaves. Results indicate that plantations on marginal lands with thin, poor and dry soils on steep slopes not only produce higher EO yield but does not compete with cereal crops for croplands. Fertilizers, insecticides and irrigation are unnecessary. This study provides important information for design and management of <em>C. longipaniculatum</em> plantations.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"123 ","pages":"Article 105091"},"PeriodicalIF":1.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144680345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A new antibacterial diarylpropanoid and other constituents from Lannea velutina A. Rich (Anacardiaceae) and their chemotaxonomic significance","authors":"Ervira Keubou Djoukam ,&nbsp;Roukayatou Mbouangouere ,&nbsp;Jean-De-Dieu Tamokou ,&nbsp;Arno R. Donfack Nanfack ,&nbsp;Germaine Matsuete-Takongmo ,&nbsp;Apollinaire Tsopmo ,&nbsp;Mathieu Tene","doi":"10.1016/j.bse.2025.105063","DOIUrl":"10.1016/j.bse.2025.105063","url":null,"abstract":"<div><div>Phytochemical investigation of the methanol extracts from the stem bark and leaves of <em>Lannea velutina</em> afforded a new diarylpropanoid (<strong>1</strong>) and eighteen previously described compounds from other plants. They included eleven flavonoids (<strong>2</strong>–<strong>12</strong>), three triterpenoids (<strong>13</strong>–<strong>15</strong>), three steroids (<strong>16</strong>–<strong>18</strong>) and one sugar (<strong>19</strong>). The structure of compound <strong>1</strong> was established by analysis of its spectroscopic and spectrometric data. All the isolated compounds are here reported for the first time from <em>L. velutina</em> species while only compounds <strong>3</strong>, <strong>6</strong>, <strong>8</strong>, <strong>10</strong>, <strong>13</strong>–<strong>16</strong> and <strong>18</strong> were previously reported from the genus <em>Lannea</em>. The extracts, fractions, and compounds were subjected to <em>in vitro</em> antibacterial assays against one Gram-positive (<em>Enterococcus faecalis</em> ATCC 29212) and three Gram-negative (<em>Escherichia coli</em> ATCC 8739, <em>Salmonella</em> Typhi ATCC 6539 and <em>Pseudomonas aeruginosa</em> 4C 76110) bacteria. The MeOH extract from the stem bark, its chromatographic fraction C and the EtOAc partitioned leaves extract showed significant activity against the growth of <em>E. faecalis</em>, <em>E. coli</em> and <em>P. aeruginosa</em> (16 ≤ MIC ≤64 μg/mL). Lannepoxide (<strong>1</strong>) inhibition activities were 16 ≤ MIC ≤128 μg/mL against the four bacterial strains. The findings demonstrated the chemotaxonomic significance of the isolated compounds and their potential as antimicrobial agents.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"123 ","pages":"Article 105063"},"PeriodicalIF":1.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144298625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}