{"title":"Biocontrol potential of metabolites from Streptomyces sp., non-toxic Aspergillus fumigatus, and their co-cultures against tomato anthracnose","authors":"Tavga Sulaiman Rashid , Hayman Kakakhan Awla , Rouhallah Sharifi","doi":"10.1016/j.bse.2025.105067","DOIUrl":"10.1016/j.bse.2025.105067","url":null,"abstract":"<div><div>The biological activity of <em>Streptomyces</em> sp. and <strong>non-toxic</strong> <em>Aspergillus fumigatus</em>, along with their metabolites in mono and co-culture, was tested against <em>Colletotrichum acutatum</em>. Additionally, the presence of volatile metabolites was observed using gas chromatography-mass spectrometry (GC-MS). The tomato plants were treated with both <em>Streptomyces</em> sp. and <em>A. fumigatus</em> separately and in combination for <em>in vivo</em> test. Both <em>Streptomyces</em> sp. and <em>A. fumigatus</em> exhibited antifungal activity against <em>C. acutatum</em>. In co-cultivation, metabolites demonstrated 100 % inhibition of the pathogenic fungus. According to GC-MS analysis, 35 compounds were identified from <em>A. fumigatus</em>, and 21 from <em>Streptomyces</em> sp. Co-cultivation of <em>A. fumigatus</em> and <em>Streptomyces</em> sp. induced the biosynthesis of 21 compounds. Most of volatile compounds present at high percentages in co-culture were not detected in the monoculture of each microorganism. The top volatiles in co-culture included acetic acid (25.58 %), furfural (9.89 %), Levulinic acid, methyl ester (7.22 %), dimethadione (6.50 %), benzene acetic acid (6.03 %), and levulinic acid (5.93 %). Significant improvements in shoot height, root length, shoot and root dry weight and the anthracnose disease reduction were observed mainly with the combination of <em>Streptomyces</em> sp. and <em>A. fumigatus</em>. These outcomes support the use of the co-cultivation technique as a viable approach for acquiring beneficial metabolites from microorganisms.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"123 ","pages":"Article 105067"},"PeriodicalIF":1.4,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144290542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ervira Keubou Djoukam , Roukayatou Mbouangouere , Jean-De-Dieu Tamokou , Arno R. Donfack Nanfack , Germaine Matsuete-Takongmo , Apollinaire Tsopmo , Mathieu Tene
{"title":"A new antibacterial diarylpropanoid and other constituents from Lannea velutina A. Rich (Anacardiaceae) and their chemotaxonomic significance","authors":"Ervira Keubou Djoukam , Roukayatou Mbouangouere , Jean-De-Dieu Tamokou , Arno R. Donfack Nanfack , Germaine Matsuete-Takongmo , Apollinaire Tsopmo , Mathieu Tene","doi":"10.1016/j.bse.2025.105063","DOIUrl":"10.1016/j.bse.2025.105063","url":null,"abstract":"<div><div>Phytochemical investigation of the methanol extracts from the stem bark and leaves of <em>Lannea velutina</em> afforded a new diarylpropanoid (<strong>1</strong>) and eighteen previously described compounds from other plants. They included eleven flavonoids (<strong>2</strong>–<strong>12</strong>), three triterpenoids (<strong>13</strong>–<strong>15</strong>), three steroids (<strong>16</strong>–<strong>18</strong>) and one sugar (<strong>19</strong>). The structure of compound <strong>1</strong> was established by analysis of its spectroscopic and spectrometric data. All the isolated compounds are here reported for the first time from <em>L. velutina</em> species while only compounds <strong>3</strong>, <strong>6</strong>, <strong>8</strong>, <strong>10</strong>, <strong>13</strong>–<strong>16</strong> and <strong>18</strong> were previously reported from the genus <em>Lannea</em>. The extracts, fractions, and compounds were subjected to <em>in vitro</em> antibacterial assays against one Gram-positive (<em>Enterococcus faecalis</em> ATCC 29212) and three Gram-negative (<em>Escherichia coli</em> ATCC 8739, <em>Salmonella</em> Typhi ATCC 6539 and <em>Pseudomonas aeruginosa</em> 4C 76110) bacteria. The MeOH extract from the stem bark, its chromatographic fraction C and the EtOAc partitioned leaves extract showed significant activity against the growth of <em>E. faecalis</em>, <em>E. coli</em> and <em>P. aeruginosa</em> (16 ≤ MIC ≤64 μg/mL). Lannepoxide (<strong>1</strong>) inhibition activities were 16 ≤ MIC ≤128 μg/mL against the four bacterial strains. The findings demonstrated the chemotaxonomic significance of the isolated compounds and their potential as antimicrobial agents.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"123 ","pages":"Article 105063"},"PeriodicalIF":1.4,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144298625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antibacterial and antioxidant potential of Aesculus indica (Wall. ex cambess.) Hook. leaf extracts along an altitudinal gradient in the Garhwal Himalaya","authors":"Namita Khantwal, C.M. Sharma, Sumeet Gairola","doi":"10.1016/j.bse.2025.105064","DOIUrl":"10.1016/j.bse.2025.105064","url":null,"abstract":"<div><div><em>Aesculus indica</em> (Indian Horse Chestnut), a medicinal plant native to the Himalayan moist temperate forests, was investigated for its antibacterial and antioxidant properties across different altitudes. Leaf samples were collected from three sites in the Garhwal Himalaya: Khirsu (1807 <em>m</em>), Adwani Forest (2109 <em>m</em>), and Kanchula-Kharak (2637 <em>m</em>). Sequential extraction using acetone, methanol, and water was performed. Antibacterial activity against <em>Staphylococcus aureus, Pseudomonas aeruginosa,</em> and <em>Escherichia coli</em> was assessed via agar well diffusion, while antioxidant capacity was measured using DPPH, FRAP, and ABTS assays. GC-MS analysis identified key phytochemicals and their variation with altitude. The methanol extract from the highest altitude (Kanchula-Kharak) demonstrated the most potent antibacterial activity against <em>Staphylococcus aureus</em>, with a maximum inhibition zone of 22.33 ± 1.53 mm and the lowest MIC (7.50 mg/mL) and MBC (15 mg/mL) values observed in the acetone extract. Antioxidant assays revealed the highest DPPH scavenging (IC<sub>50</sub> 27.87 ± 4.47 μg/mL) and ABTS inhibition (94.46 ± 1.27 %) in Kanchula-Kharak extracts, while the Adwani Forest methanol extract exhibited the highest FRAP value (62.65 ± 1.97 mmol Fe<sup>2+</sup>E/mg). GC-MS profiling revealed diverse phytocompounds, primarily triterpenoids, fatty acids, lipids, and hydrocarbons. Both antibacterial and antioxidant activities increased significantly with altitude. These findings suggest that altitude positively influences the medicinal potential of <em>A. indica</em>, highlighting potential harvesting sites and their value for herbal formulation.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"123 ","pages":"Article 105064"},"PeriodicalIF":1.4,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144298626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Volatile oil content and composition in fresh and dried Lavandula species: The impact of distillation time","authors":"Emir Soltanbeigi , Hasan Maral","doi":"10.1016/j.bse.2025.105066","DOIUrl":"10.1016/j.bse.2025.105066","url":null,"abstract":"<div><div>A wide range of biotic and abiotic factors influence both the yield and quality of essential oils (EOs). Among post-harvest processes, distillation time (DT) plays a pivotal role in shaping the EO yield and its chemical composition. This study investigates the effects of DT on the EO yield and volatile compound profiles of lavender (<em>Lavandula angustifolia</em> L.) and lavandin (<em>Lavandula</em> × <em>intermedia</em> L.) obtained from fresh and dried stemless flowers. To this end, five different distillation durations were assessed: 1, 2, 3, 4, and 5 h. In general, EO yield increased progressively with extended DTs. The maximum EO yield in fresh and dried lavender was obtained at 3 h (3.25 %) and 5 h (7.6 %) of distillation, respectively. Similarly, the highest EO yields in fresh and dried lavandin flowers were recorded at 3 h (3.2 %) and 4 h (7.2 %) of distillation, respectively. Notably, fresh floral material yielded proportionally higher EO content in both species. GC/FID-MS analysis revealed linalool (39.80–52.75 %) as the dominant compound across all samples. Other major constituents in lavender included linalyl acetate (16.74–23.10 %), terpinen-4-ol (5.24–6.79 %), and lavandulyl acetate (2.37–3.60 %). In lavandin, the principal compounds were camphor (10.93–12.99 %), 4-terpineol (7.60–8.23 %), borneol (6.77–7.52 %), 1,8-cineole (5.39–6.03 %), and linalyl acetate (2.21–3.83 %). Extended distillation time enhances essential oil yield and alters the chemical profile, particularly increasing the proportion of key compounds like linalool and camphor. For optimal yield and market-aligned composition, a DT of 3–5 h is recommended depending on flower condition and species.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"123 ","pages":"Article 105066"},"PeriodicalIF":1.4,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144289018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhongying Fang , Yingqi Liu , Lei Fang , Nana Jiang , Yongqing Zhang , Zhenguo Wang
{"title":"Pentacyclic triterpenoid saponins from the flower buds of Lonicera macranthoides Hand.-Mazz. and their chemotaxonomic significance","authors":"Zhongying Fang , Yingqi Liu , Lei Fang , Nana Jiang , Yongqing Zhang , Zhenguo Wang","doi":"10.1016/j.bse.2025.105052","DOIUrl":"10.1016/j.bse.2025.105052","url":null,"abstract":"<div><div>A phytochemical investigation of the flower buds of <em>Lonicera macranthoides</em> Hand.-Mazz. led to the isolation of twenty-three pentacyclic triterpenoid saponins, including three lupine-type (<strong>1–3</strong>), thirteen hederin-type (<strong>4–16</strong>), six oleanane-type (<strong>17–22</strong>) and one gypsogenic acid-type (<strong>23</strong>). The structures of these saponins were identified based on extensive spectroscopic methods as well as comparison with literature data. To the best of our knowledge, compounds <strong>1–9</strong>, <strong>11–21</strong> and <strong>23</strong> were isolated from <em>L</em>. <em>macranthoides</em> for the first time, compounds <strong>12</strong>, <strong>15–16</strong> and <strong>20–21</strong> were newly identified within the genus <em>Lonicera</em>. Compounds <strong>1–3</strong>, <strong>5–8</strong>, <strong>11</strong>, <strong>14</strong>, <strong>19</strong> and <strong>23</strong> were firstly acquired from the family Caprifoliaceae. The chemotaxonomic significance of these isolated pentacyclic triterpenoid saponins was also described.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"123 ","pages":"Article 105052"},"PeriodicalIF":1.4,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144263630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gui-fang Li , Xin Wang , Hong-ying Chen , Shuai Huang , Lin Chen , Xian-li Zhou
{"title":"Chemical constituents of Rhododendron virgatum Hook and their chemotaxonomic significance","authors":"Gui-fang Li , Xin Wang , Hong-ying Chen , Shuai Huang , Lin Chen , Xian-li Zhou","doi":"10.1016/j.bse.2025.105059","DOIUrl":"10.1016/j.bse.2025.105059","url":null,"abstract":"<div><div>Sixteen compounds were isolated from the whole plant of <em>Rhododendron virgatum</em> Hook by silica gel column chromatography and MCI column chromatography, including ten triterpenoids (<strong>1</strong>, <strong>2</strong>, <strong>4</strong>, <strong>6</strong>, <strong>8–11</strong>, <strong>15</strong>, <strong>16</strong>), one sterol (<strong>7</strong>), one flavonoid (<strong>12</strong>), one phenolic compound (<strong>13</strong>) and one phenylpropanoid compound (<strong>14</strong>), together with two unusual chromane derivatives (<strong>3</strong> and <strong>5</strong>). Structures of all compounds were identified by comprehensive analyses of physicochemical properties and NMR data. All compounds were isolated from <em>R</em>. <em>virgatum</em> for the first time. Among them, compounds <strong>5</strong>, <strong>14</strong> and <strong>16</strong> were isolated from the genus <em>Rhododendron</em> for the first time. Additionally, the potential insecticidal activity of the isolated compounds was also evaluated <em>in vitro</em> by testing their inhibition rate against Sf9 cells. The significance of these compounds in chemotaxonomy was assessed through their chemical profiles and distribution across <em>Rhododendron</em> species.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"123 ","pages":"Article 105059"},"PeriodicalIF":1.4,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144243434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Biochemical analysis of petals in Rosa species (Rosaceae) from Iran using gas chromatography-mass spectrometry","authors":"Sareh Seyedipour, Kazem Mahdigholi, Vahid Niknam","doi":"10.1016/j.bse.2025.105056","DOIUrl":"10.1016/j.bse.2025.105056","url":null,"abstract":"<div><div>This study investigates the phytochemical composition, with a focus on alkane profiles, of petals from eight <em>Rosa</em> species native to Iran using gas chromatography–mass spectrometry (GC-MS). Flowers were collected from healthy individuals in wild populations across diverse regions of Iran, including the Alborz mountain range, at altitudes between 1546 and 2597 m. The dried petals were extracted using the Bligh and Dyer method and analyzed with GC-MS under standardized chromatographic conditions. The analysis revealed 81 distinct phytochemical compounds across the studied species, including a range of alkanes. Identified compounds included 32 alkanes, 4 triterpenoids, 4 phytosterols/steroids, 3 fatty acid methyl esters, 3 phenols, 2 phthalate esters, 2 alkenes, 1 oxaspiro compound, and other minor constituents such as alkylbenzenes, benzoate esters, and vitamin E. Alkane chain lengths ranged from C<sub>12</sub> to C<sub>44</sub>, with interspecific variation in both diversity and abundance. Multivariate statistical analyses, including cluster analysis (UPGMA), Pearson correlation, and principal component analysis (PCA), were applied to assess interspecific chemical variation and species relationships. Pearson correlation analysis revealed strong positive associations between species such as <em>R. beggeriana</em> and <em>R. iberica</em> (p < 0.001), as well as among specific alkane compounds (r > 0.92, p < 0.0001), suggesting shared biosynthetic pathways. A significant finding of this study is the first report of 7,9-di-<em>tert</em>-butyl-1-oxaspiro[4.5]deca-6,9-diene-2,8-dione in <em>Rosa</em> petals. These results enhance the chemotaxonomy of the <em>Rosa</em> genus and suggest potential therapeutic and nutritional uses for wild <em>Rosa</em> species.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"123 ","pages":"Article 105056"},"PeriodicalIF":1.4,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144243433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"First report on seasonal variations in chemical composition and pesticidal activities of Alpinia nigra rhizome essential oil","authors":"Shailja Singh , Om Prakash , Ravendra Kumar , Tanuja Kabdal , Stuti Arya , Shiv Kumar Dubey , Dharmendra Singh Rawat , Satya Kumar","doi":"10.1016/j.bse.2025.105055","DOIUrl":"10.1016/j.bse.2025.105055","url":null,"abstract":"<div><div>Present study reveals the investigation of seasonal variation in chemical composition and pesticidal activities of essential oils obtained from <em>Alpinia nigra</em> (Gaertn.) Burtt syn. <em>Alpinia allughas</em> (Retz.) rhizomes, analyzed month wise from November 2021 to October 2022. With the help of GC-MS analysis over 28 compounds were identified, with β-pinene (6.6–36 %), 1,8-cineole (2.2–17.3 %), and 4-terpineol (6.6–25.7 %) as major constituents, showing significant seasonal variations. Biological assays demonstrated significant nematicidal, antifeedant, and herbicidal activities due to qualitative and quantitative variation in the constituents. The nematicidal activity against <em>Meloidogyne incognita</em> was highest in October (98.95 %) and reached its lowest level in August (58.66 %). Antifeedant activity against <em>Spodoptera litura</em> was observed 85.07 % in September and 16.93 % in winter. Herbicidal activity against <em>Raphanus sativus</em> was 100 % in December, March, and June, inhibiting seed germination, root, and shoot length. These findings emphasize the potential of <em>A. nigra</em> essential oils as eco-friendly alternatives for integrated pest and weed management. Seasonal optimization for harvesting and application enhances efficacy. Future research should explore molecular mechanisms, synergistic interactions, and scalable production methods to maximize their agricultural and commercial applications. This study establishes <em>A. nigra</em> essential oils as a possible sustainable solution for pest and weed control.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"123 ","pages":"Article 105055"},"PeriodicalIF":1.4,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144242997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nguyen Viet Phong , Cai-Yi Wang , Sung Don Lim , Seo Young Yang
{"title":"Characterization of a new jasmonate derivative and chemotaxonomical significance of secondary metabolites in the seeds of black soybean (Glycine max)","authors":"Nguyen Viet Phong , Cai-Yi Wang , Sung Don Lim , Seo Young Yang","doi":"10.1016/j.bse.2025.105060","DOIUrl":"10.1016/j.bse.2025.105060","url":null,"abstract":"<div><div>A comprehensive phytochemical investigation of black soybean (<em>Glycine max</em>) led to the isolation of five compounds, including a new jasmonate derivative (<strong>1</strong>), a <em>β</em>-sitosterol glucoside derivative (<strong>2</strong>), two isoflavone glycosides (<strong>3</strong> and <strong>4</strong>), and an aurone glycoside derivative (<strong>5</strong>). Their chemical structures were determined using nuclear magnetic resonance (NMR) spectroscopy and comparison with previously reported data. The absolute configuration of the new jasmonate derivative (<strong>1</strong>) was determined through density functional theory calculations of NMR chemical shifts and DP4+ probability analysis. Additionally, marsuposide (<strong>5</strong>) was identified in black soybean for the first time, expanding the known chemical profile of this crop. Notably, the occurrence of these metabolites provides potential chemotaxonomic markers within the Fabaceae family, highlighting unique metabolic traits of black soybean. These findings contribute not only to the understanding of the secondary metabolism of the species but also to broader discussions on the diversification of legume-specific phytochemicals. The potential agricultural and biological significance of these metabolites is discussed, along with their chemotaxonomic significance, offering insights into the phytochemical composition of black soybean and its relevance to crop improvement and plant classification.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"123 ","pages":"Article 105060"},"PeriodicalIF":1.4,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144242996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nguyen Huu Toan Phan , Pham Van Huyen , Tran Thi Ngoc Hanh , Nguyen Thi Thu Hien , Nguyen Huu Huong Duyen , Nguyen Thi Dieu Thuan
{"title":"Secondary metabolites of Magnolia lamdongensis leaves and their chemotaxonomic significance","authors":"Nguyen Huu Toan Phan , Pham Van Huyen , Tran Thi Ngoc Hanh , Nguyen Thi Thu Hien , Nguyen Huu Huong Duyen , Nguyen Thi Dieu Thuan","doi":"10.1016/j.bse.2025.105058","DOIUrl":"10.1016/j.bse.2025.105058","url":null,"abstract":"<div><div><em>Magnolia lamdongensis</em> (Magnoliaceae), an endemic species of Vietnam, was selected for our study on its chemical composition. By various chromatographic techniques, sixteen compounds were isolated for the first time from the methanol extract of <em>M</em>. <em>lamdongensis</em> leaves, including five flavonoids (<strong>1</strong>–<strong>5</strong>), six lignans (<strong>6</strong>–<strong>11</strong>), a phenylpropanoid (<strong>12</strong>), a phenolic glycoside (<strong>13</strong>), a phenylethanoid glycoside (<strong>14</strong>), and two cerebrosides (<strong>15</strong>–<strong>16</strong>). The structures of the compounds were elucidated using NMR, MS, and CD spectra. Flavonoids, lignans, phenylpropanoids, phenolic glycosides, and phenylethanoid glycosides have been widely reported from <em>Magnolia</em>; however, the cerebrosides have not been discussed in this genus in the previous literature.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"122 ","pages":"Article 105058"},"PeriodicalIF":1.4,"publicationDate":"2025-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144229520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}