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Geographic based phenolic compound variations in South African Schinus molle L. peppercorns 南非 Schinus molle L. 花椒中基于地理位置的酚类化合物变化
IF 1.4 4区 生物学
Biochemical Systematics and Ecology Pub Date : 2024-10-07 DOI: 10.1016/j.bse.2024.104905
Callistus Bvenura, Learnmore Kambizi
{"title":"Geographic based phenolic compound variations in South African Schinus molle L. peppercorns","authors":"Callistus Bvenura,&nbsp;Learnmore Kambizi","doi":"10.1016/j.bse.2024.104905","DOIUrl":"10.1016/j.bse.2024.104905","url":null,"abstract":"<div><div>Environmental conditions affect polyphenolic compounds in plants, and yet little is known about the response of <em>Schinus molle</em> peppercorns to geographical location. <em>S molle</em> is a folkloric pseudospice of Andean origin possessing multiple culinary and medicinal functions. This globally invasive species presents an immense multidimensional potential. Polyphenolic compounds were therefore profiled and quantified from pink peppercorns growing in 12 distinct locations in the Eastern and Western Cape provinces of South Africa using UPLC-QTOF-MS techniques. Eleven flavonoids were reported, including epigallocatechin gallate, +)-tephrorin B, astilbin, procyanidin B5, 4-benzyl-7-hydroxy-3-phenyl-2H-chromen-2-one, and isochamaejasmin which were reported for the first time in this species. Five phenolic acids, three glycosides, and tannins (theogallin (3-galloylquinic acid), digalloyl quinic acid, digalloylshikimic acid, β-glucogallin A and β-glucogallin B) were also revealed among others. PCA revealed a high composition of polyphenolic compounds in the Eastern in comparison to the Western Cape regions. Flavonoids were glaringly higher in winter rainfall receiving coastal regions. Consequently, the highest catechin content was 229% higher in the Eastern (1269.9 mg/kg) than the Western Cape (553.4 mg/kg). Furthermore, isochamaejasmin, the compound with possibly the highest concentration is reported in George (1741 mg/kg) and Gqeberha (2601.2 mg/kg) representing 149% differences between the two regions. Soil type alone did not conclusively appear to influence polyphenolic compound accumulation in this study. Elucidating the distribution of polyphenolic compounds in this species could open new insights for potential therapeutic, pharmaceutical, and agricultural applications including possibilities for new and improved organic drugs, and food product development.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142419618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chemophenetic significance and antibacterial activity of extract, various fractions and secondary metabolites from the stem bark of Ochna afzelii R. Br. (ex Oliv.) Ochna afzelii R. Br. (ex Oliv.)
IF 1.4 4区 生物学
Biochemical Systematics and Ecology Pub Date : 2024-10-06 DOI: 10.1016/j.bse.2024.104909
Morel Hervé D. Kakabi , Arno R. Donfack Nanfack , Jean-De-Dieu Tamokou , James D. Simo Mpetga , Romeo Désiré T. Nago , Muhammad Shaiq Ali , Mathieu Tene , Augustin Silvère Ngouela
{"title":"Chemophenetic significance and antibacterial activity of extract, various fractions and secondary metabolites from the stem bark of Ochna afzelii R. Br. (ex Oliv.)","authors":"Morel Hervé D. Kakabi ,&nbsp;Arno R. Donfack Nanfack ,&nbsp;Jean-De-Dieu Tamokou ,&nbsp;James D. Simo Mpetga ,&nbsp;Romeo Désiré T. Nago ,&nbsp;Muhammad Shaiq Ali ,&nbsp;Mathieu Tene ,&nbsp;Augustin Silvère Ngouela","doi":"10.1016/j.bse.2024.104909","DOIUrl":"10.1016/j.bse.2024.104909","url":null,"abstract":"<div><div>Chemical investigation of the acetone-soluble sub-fraction of the methanolic extract of the stem bark of <em>Ochna afzelii</em> R. Br. (ex Oliv.) led to the isolation of fourteen known secondary metabolites comprising two dimeric chalcones namely dihydrolophirone M <strong>(</strong><strong>1</strong><strong>)</strong> and lophirone L (<strong>2</strong>), two rearranged biflavonoids: lophirone A (<strong>3</strong>) and 4‴-methoxylophirone A (<strong>4</strong>), two biflavanone derivatives: biflavanone I (<strong>5</strong>) and biflavanone II (<strong>6</strong>), two isoflavonoids: methylirisolin (<strong>7</strong>) and biochanin A (<strong>8</strong>), one flavanol: epicatechin (<strong>9</strong>), one phenolic acid: 3,4-dihydroxybenzoic acid (<strong>10</strong>), one anthraquinone: physcion (<strong>11</strong>), two triterpenoids: lupeol (<strong>12</strong>) and oleanolic acid (<strong>13</strong>), and one steroid: sitosterol-3-<em>O</em>-<em>β</em>-<span>d</span>-glucopyranoside (<strong>14</strong>). Biochanin A (<strong>8</strong>) and 3,4-dihydroxybenzoic acid (<strong>10</strong>) are herein reported for the first time from the family Ochnaceae. The antibacterial activity was assessed <em>in vitro</em> against pathogenic strains of <em>Escherichia coli</em>, <em>Pseudomonas aeruginosa</em>, <em>Staphylococcus aureus</em> and <em>Enterococcus faecalis</em>. The crude methanolic extract as well as its acetone-soluble and insoluble fractions exhibited high to significant antibacterial activity, while isolated compounds mostly displayed moderate antibacterial activity (MIC = 16–64 μg/mL).</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142419670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Natural products and chemotaxonomic studies from the twigs of Neobalanocarpus heimii (King) P.S. Ashton (Dipterocarpaceae, Malvales) Neobalanocarpus heimii (King) P.S. Ashton (Dipterocarpaceae, Malvales) 小枝的天然产物和化学分类学研究
IF 1.4 4区 生物学
Biochemical Systematics and Ecology Pub Date : 2024-10-05 DOI: 10.1016/j.bse.2024.104906
Nurul Shahira Zakaria , NorulNazilah Ab'lah , Aisyah Salihah Kamarozaman , Nik Fatini Nik Azmin , Farah Aliah Izzati Azman , Mohd Izwan Mohamad Yusof , Syafiqah Saidin , Norizan Ahmat
{"title":"Natural products and chemotaxonomic studies from the twigs of Neobalanocarpus heimii (King) P.S. Ashton (Dipterocarpaceae, Malvales)","authors":"Nurul Shahira Zakaria ,&nbsp;NorulNazilah Ab'lah ,&nbsp;Aisyah Salihah Kamarozaman ,&nbsp;Nik Fatini Nik Azmin ,&nbsp;Farah Aliah Izzati Azman ,&nbsp;Mohd Izwan Mohamad Yusof ,&nbsp;Syafiqah Saidin ,&nbsp;Norizan Ahmat","doi":"10.1016/j.bse.2024.104906","DOIUrl":"10.1016/j.bse.2024.104906","url":null,"abstract":"<div><div><em>Neobalanocarpus heimii</em> is one of the toughest timbers in the world and resistant to termites and fungi. Phytochemical investigation from the twigs of <em>N. heimii</em> led to the isolation of eight resveratrol oligomers namely <em>trans</em>-resveratrol <strong>(1)</strong>, (−)-ε-viniferin <strong>(2)</strong>, balanocarpol <strong>(3)</strong>, ampelopsin A <strong>(4)</strong>, (+)-α-viniferin <strong>(5)</strong>, vaticanol A <strong>(6)</strong>, vaticanol B <strong>(7)</strong> and hopeaphenol <strong>(8)</strong>. The structures of the isolated compounds were successfully elucidated using various spectroscopic techniques as well as comparison with the literature data. The chemotaxonomic significance of the isolated compounds was summarized, along with a compound-genus network analysis.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142419673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chemical constituents of Ulmus pumila L. and their chemotaxonomic significance 榆树的化学成分及其化学分类学意义
IF 1.4 4区 生物学
Biochemical Systematics and Ecology Pub Date : 2024-10-04 DOI: 10.1016/j.bse.2024.104907
Deri Hu , Zhenyu Liu , Yue Yu , Chenghao Wu , Jinze Liu , Dongzhou Kang , Junzhe Min , Mingshan Zheng
{"title":"Chemical constituents of Ulmus pumila L. and their chemotaxonomic significance","authors":"Deri Hu ,&nbsp;Zhenyu Liu ,&nbsp;Yue Yu ,&nbsp;Chenghao Wu ,&nbsp;Jinze Liu ,&nbsp;Dongzhou Kang ,&nbsp;Junzhe Min ,&nbsp;Mingshan Zheng","doi":"10.1016/j.bse.2024.104907","DOIUrl":"10.1016/j.bse.2024.104907","url":null,"abstract":"<div><div>A phytochemical study of the leaves of <em>Ulmus pumila</em> L. led to the isolation of 32 compounds, including fourteen flavonoids, which include flavonols (<strong>1</strong>–<strong>6</strong>), dihydroflavones (<strong>7</strong>–<strong>11</strong>), and dihydroflavonols (<strong>12</strong>–<strong>14</strong>), five terpenoids, which include megastigmane glycosides (<strong>15</strong>–<strong>17</strong>) and triterpenoids (<strong>18</strong>–<strong>19</strong>), four sugars (<strong>20</strong>–<strong>23</strong>), one phenylpropanoid (<strong>24</strong>), two phenolic glycosides (<strong>25</strong>–<strong>26</strong>), two aromatic glycosides (<strong>27</strong>–<strong>28</strong>), one phenolic (<strong>29</strong>), one lignan glycoside (<strong>30</strong>), one steroid glycoside (<strong>31</strong>), and one <span><span>fatty acid</span><svg><path></path></svg></span> (<strong>32</strong>). The structures of these isolated compounds were determined by analysis of their NMR spectroscopic (<sup>1</sup>H and <sup>13</sup>C) data and by comparison with previously reported data. Compounds <strong>4</strong> and <strong>8</strong>–<strong>10</strong> were first reported from <em>U. pumila</em>; compound <strong>12</strong> was obtained from the genus <em>Ulmus</em> for the first time, while compounds <strong>2</strong>, <strong>6</strong>, <strong>7</strong>, <strong>11</strong>, <strong>13</strong>, <strong>15</strong>–<strong>17</strong>, <strong>19</strong>–<strong>28</strong>, <strong>30</strong>, and <strong>32</strong> have never been isolated from the Ulmaceae family. Chemotaxonomic studies have shown that the genus <em>Ulmus</em> may be closely related to the genera <em>Hemiptelea</em>, <em>Zelkova</em>, and <em>Holoptelea</em>.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142419672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
3-Hydroxy-2-methylpropylglucosinolate and other glucosinolates from Reseda luteola (Resedaceae) 3-Hydroxy-2-methylpropylglucosinolate and other glucosinolates from Reseda luteola (Resedaceae)
IF 1.4 4区 生物学
Biochemical Systematics and Ecology Pub Date : 2024-09-16 DOI: 10.1016/j.bse.2024.104902
Gina R. De Nicola , Jianzhong Zhu , David I. Pattison , Marcus A. Koch , Dan Staerk , Niels Agerbirk
{"title":"3-Hydroxy-2-methylpropylglucosinolate and other glucosinolates from Reseda luteola (Resedaceae)","authors":"Gina R. De Nicola ,&nbsp;Jianzhong Zhu ,&nbsp;David I. Pattison ,&nbsp;Marcus A. Koch ,&nbsp;Dan Staerk ,&nbsp;Niels Agerbirk","doi":"10.1016/j.bse.2024.104902","DOIUrl":"10.1016/j.bse.2024.104902","url":null,"abstract":"<div><p>We identified 3-hydroxy-2-methylpropylglucosinolate in foliage of <em>Reseda luteola</em> L, although the side chain stereochemistry was not resolved. The glucosinolates (GSLs) in <em>R. luteola</em> extracts were bound to an anion exchange column and enzymatically desulfated, followed by isolation by preparative HPLC of the desulfo derivatives, the structures of which were elucidated by NMR and/or MS/MS. Presence of intact 3-hydroxy-2-methylpropylGSL in extracts was supported by direct LC-MS detection and MS2 loss of HSO<sub>4</sub><sup>−</sup>. Prominent GSLs in <em>R. luteola</em> foliage were 3-hydroxy-2-methylpropylGSL as well as the previously known indol-3-ylmethylGSL and the 2<em>R</em> (minor) and 2<em>S</em> (major) isomers of 2-hydroxy-2-phenylethylGSL. Minor GSLs included the expected biosynthetic precursors 2-methylpropylGSL (tentative) and phenethylGSL, as well as 1-methylpropylGSL (tentative) and benzylGSL. The 3-hydroxy-2-methylpropylGSL matched a previously reported but so far unidentified constituent in <em>Limnanthes alba</em> (Limnanthaceae). The identity of investigated <em>R. luteola</em> was confirmed morphologically and from DNA barcoding, and a <em>Reseda</em> phylogeny was constructed. In conclusion, 3-hydroxy-2-methylpropylGSL occurs in at least two basal families of the Brassicales order.</p></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0305197824001200/pdfft?md5=6501b2a059cdcd25bb018ae0af9f1681&pid=1-s2.0-S0305197824001200-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142241440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diurnal, and seasonal dynamics in essential oil content and composition of cultivated Helichrysum italicum (Roth) G. Don 栽培腊菊(Helichrysum italicum (Roth) G. Don)精油含量和成分的昼夜和季节动态变化
IF 1.4 4区 生物学
Biochemical Systematics and Ecology Pub Date : 2024-09-14 DOI: 10.1016/j.bse.2024.104888
Nadire Pelin Bahadırlı , Mehmet Uğur Yıldırım , Ercüment Osman Sarıhan
{"title":"Diurnal, and seasonal dynamics in essential oil content and composition of cultivated Helichrysum italicum (Roth) G. Don","authors":"Nadire Pelin Bahadırlı ,&nbsp;Mehmet Uğur Yıldırım ,&nbsp;Ercüment Osman Sarıhan","doi":"10.1016/j.bse.2024.104888","DOIUrl":"10.1016/j.bse.2024.104888","url":null,"abstract":"<div><p><em>Helichrysum italicum</em> from the Asteraceae family is a small odorous shrub that is distributed in the Mediterranean region different altitudes. However, the species was not naturally found in the flora of Türkiye. Cultivation interest in <em>H. italicum</em> has grownsince its cosmetic and pharmaceutical usage. In the present study, <em>H. italicum</em> plants (seedlings were obtained from the same source) were cultivated in Hatay (Mediterranean, 149 m altitude) and Uşak (Continental, 906 m altitude) cities of Türkiye. Harvestings were done in the spring and autumn, at three different hours of the day (09.<sup>00</sup>, 13.<sup>00,</sup> and 18.<sup>00</sup>) in both locations. Soil samples were analyzed to determine some soil properties in both locations. Harvested aerial plant samples were evaluated for essential oil content and composition with three replicates. The experimental field soils' pH values were similar, however there were differences in the ratio of soil lime and macro-microelements. The essential oil content varied between 0.29 and 0.59% in all examined variables. Generally, neryl acetate and α-pinene were found as a main component in all essential oils. Neryl acetate contents ranged between 8.07 and 36.66%, while α-pinene content was found between 13.93 and 31.18%. In the spring harvest, harvesting in the evening produced higher neryl acetate in the continental environment, whereas harvesting at any time of day did not affect the amount of neryl acetate in the Mediterranean climate. In the autumn harvest in the Mediterranean environment, the neryl acetate content was higher in the morning harvest, while neryl acetate content in autumn was comparatively low in the continental climate. Examining the seasons has shown that, in a Mediterranean environment, harvest time is not very significant, but in a continental climate, spring harvest could be favored.</p></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142229076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cytotoxicity of endemic Haplophyllum megalanthum Bornm. and its newly isolated alkaloids and lignans 当地特有的 Haplophyllum megalanthum Bornm.及其新分离的生物碱和木脂素的细胞毒性
IF 1.4 4区 生物学
Biochemical Systematics and Ecology Pub Date : 2024-09-14 DOI: 10.1016/j.bse.2024.104901
Serhat Demir , Malene Johanne Petersen , Louise Kjaerulff , Nehir Unver-Somer , Dan Staerk
{"title":"Cytotoxicity of endemic Haplophyllum megalanthum Bornm. and its newly isolated alkaloids and lignans","authors":"Serhat Demir ,&nbsp;Malene Johanne Petersen ,&nbsp;Louise Kjaerulff ,&nbsp;Nehir Unver-Somer ,&nbsp;Dan Staerk","doi":"10.1016/j.bse.2024.104901","DOIUrl":"10.1016/j.bse.2024.104901","url":null,"abstract":"<div><p>In this study, two previously unreported lignans [4′-<em>O</em>-demetylsuchilactone-8′-ol (<strong>1</strong>), 7-<em>O</em>-(3-methyl-2,3-dihydroxy-butyl)isodaurinol] (<strong>2</strong>), four new alkaloids (haplomegalanthine (<strong>3</strong>), megalantin (<strong>4</strong>), megalanthamide (<strong>5</strong>), glycoisohaplopine (<strong>6</strong>) and thirty-five known compounds (<strong>7–41</strong>) were isolated from <em>Haplophyllum megalanthum</em> Bornm. (Rutaceae). Pinoresinol (<strong>23</strong>), epipinoresinol (<strong>24</strong>), indole-3-carbaldehyde (<strong>29</strong>), <em>N</em>-[2-(4-hydroxyphenyl)ethyl]-3-methylbut-2-enamide (<strong>34</strong>), 7,8-dimethoxyfuroquinoline-4-one (<strong>35</strong>), <em>cis</em>-khellactone (<strong>36</strong>), 4,4′-dihydroxy-3,3′,9-trimethoxy-9,9′-epoxylignan (<strong>37</strong>), ulopterol (<strong>39</strong>) and <em>trans</em>-decursidinol (<strong>40</strong>) were identified for the first time in the genus <em>Haplophyllum</em>. Also, 4′-<em>O</em>-demethylsuchilactone (<strong>16</strong>) and <em>N</em>-(4-hydroxyphenethyl)benzamide (<strong>32</strong>) were found for the first time within the family Rutaceae. Structures of the compounds were elucidated by the use of HRMS, UHPLC-MS and 1D/2D NMR analyses. Furthermore, cytotoxic activity of the crude extract and previously unreported compounds (1–3, 5, 6) on colon cancer cell line HT29 were tested by the MTT method. IC<sub>50</sub> values were determined for these five compounds and the crude extract as 18.48 ± 0.94 μg/ml, 52.62 ± 7.27 μg/ml, 23.15 ± 6.70 μg/ml, 21.45 ± 2.48 μg/ml, 5.06 ± 0.19 μg/ml and 2.82 ± 0.012 μg/ml, respectively.</p><p>The present report is the first detailed phytochemical investigation of the title plant pointing out that it comprises a rich source of diverse chemical constituents including new compounds with promising cytotoxic activity.</p></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142229181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hesperidin and 5, 7-dimethoxycoumarin act as markers in the chemotaxonomy of Citrus medica L. var. sarcodactylis Swingle and Citrus medica L. 橙皮甙和5, 7-二甲氧基香豆素在柑橘变种sarcodactylis Swingle和Citrus medica L.的化学分类中起标记作用
IF 1.4 4区 生物学
Biochemical Systematics and Ecology Pub Date : 2024-09-12 DOI: 10.1016/j.bse.2024.104900
Di Wu , Miao-Miao Zhang , Hong-Ping Long , Xiao-Yuan Lin , Kai Liu
{"title":"Hesperidin and 5, 7-dimethoxycoumarin act as markers in the chemotaxonomy of Citrus medica L. var. sarcodactylis Swingle and Citrus medica L.","authors":"Di Wu ,&nbsp;Miao-Miao Zhang ,&nbsp;Hong-Ping Long ,&nbsp;Xiao-Yuan Lin ,&nbsp;Kai Liu","doi":"10.1016/j.bse.2024.104900","DOIUrl":"10.1016/j.bse.2024.104900","url":null,"abstract":"<div><p><em>Citrus medica</em> L. var. <em>Sarcodactylis</em> Swingle and <em>C. medica</em> L. were the subject of a chemotaxonomic inquiry using high-performance liquid chromatography (HPLC) fingerprint and multivariate data analysis, including hierarchical cluster analysis (HCA), principal component analysis (PCA), and orthogonal partial least squares-discriminant analysis (OPLS-DA). The results are in good agreement with current knowledge of the systematics of <em>C. medica</em> var. <em>Sarcodactylis</em> and <em>C. medica</em>. The analysis of Citri Sarcodactylis Fructus (CSF) and Citri Fructus (CF) showed that their chemical composition was highly similar except for the content; hesperidin (HP) and 5, 7-dimethoxycoumarin (DMC) were distinguishing markers for <em>C. medica</em> var. <em>Sarcodactylis</em> and <em>C. medica</em>; CSF had a significantly higher concentration of DMC than CF; additionally, the content ratio of HP to DMC in CSF was less than one (0.2401–0.7953), but in CF, it was more than one (2.5775–25.7800). The present work revealed the chemotaxonomic significance of HP and DMC for <em>C. medica</em> var. <em>Sarcodactylis</em> and <em>C. medica</em> and validated the traditional plant taxonomy regarding the two species at the chemical level.</p></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142172838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A new benzoic acid derivative from Gentiana davidi and its chemotaxonomic significance 龙胆草中一种新的苯甲酸衍生物及其化学分类学意义
IF 1.4 4区 生物学
Biochemical Systematics and Ecology Pub Date : 2024-09-08 DOI: 10.1016/j.bse.2024.104899
Jiang-Li Peng , Qiu-Xian Peng , Peng Wang , Juan Li , Shun-Xiang Li
{"title":"A new benzoic acid derivative from Gentiana davidi and its chemotaxonomic significance","authors":"Jiang-Li Peng ,&nbsp;Qiu-Xian Peng ,&nbsp;Peng Wang ,&nbsp;Juan Li ,&nbsp;Shun-Xiang Li","doi":"10.1016/j.bse.2024.104899","DOIUrl":"10.1016/j.bse.2024.104899","url":null,"abstract":"<div><p>Phytochemical investigation of <em>Gentiana davidi</em> led to isolation of a total of 21 compounds, including seven benzoic acid derivatives (<strong>1</strong>–<strong>7</strong>), one alkaloid compound (<strong>8</strong>), seven iridoids (<strong>9</strong>–<strong>15</strong>), and six flavonoids (<strong>16</strong>–<strong>21</strong>). The chemical structures of these compounds were characterized by spectroscopic analysis, and their NMR data were compared with those reported in the literature. Among them, compound <strong>1</strong> was identified as a new benzoic acid derivative, and compounds <strong>2</strong>–<strong>21</strong> are identified and reported for the first time from this plant. The chemotaxonomic significance of these isolated compounds from the <em>G. davidi</em> is discussed.</p></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142158333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pharmacological insights into Laurus nobilis: HPLC profiling and evaluation of its anti-Toxoplasma, antioxidant, and anti-hemolytic properties 金叶月桂的药理作用:高效液相色谱分析及其抗支原体、抗氧化和抗溶血特性的评估
IF 1.4 4区 生物学
Biochemical Systematics and Ecology Pub Date : 2024-09-03 DOI: 10.1016/j.bse.2024.104891
Othman El Faqer , Ismail Elkoraichi , Mounia Latif , Françoise Debierre-Grockiego , Zaynab Ouadghiri , Samira Rais , Isabelle Dimier-Poisson , El Mostafa Mtairag
{"title":"Pharmacological insights into Laurus nobilis: HPLC profiling and evaluation of its anti-Toxoplasma, antioxidant, and anti-hemolytic properties","authors":"Othman El Faqer ,&nbsp;Ismail Elkoraichi ,&nbsp;Mounia Latif ,&nbsp;Françoise Debierre-Grockiego ,&nbsp;Zaynab Ouadghiri ,&nbsp;Samira Rais ,&nbsp;Isabelle Dimier-Poisson ,&nbsp;El Mostafa Mtairag","doi":"10.1016/j.bse.2024.104891","DOIUrl":"10.1016/j.bse.2024.104891","url":null,"abstract":"<div><p><em>Toxoplasma gondii (T. gondii)</em> poses significant risks, especially to those with weakened immune systems, highlighting the need for new, less toxic treatments. <em>Laurus nobilis</em> L. (<em>L. nobilis</em>), known for its beneficial properties including antiparasitic and antioxidant effects, offers potential for innovative therapies. This study assessed the anti-Toxoplasma, cytotoxic, antioxidant, and anti-hemolytic effects of <em>L. nobilis</em>'s aqueous and ethanolic extracts both <em>in vitro</em> and <em>in silico</em>, including a phytochemical analysis. HPLC analysis identified a range of phenolic compounds, notably syringic acid, ferulic acid, gallic acid, caffeine, and quercetin. Both extracts exhibited an inhibitory effect on the growth of <em>T. gondii</em> tachyzoites <em>in vitro</em> and caused less cytotoxicity to host cells. <em>In silico</em> studies revealed that rutin and quercetin were the most potent compounds, with binding affinity scores for the DHFR enzyme of −10.6 and −9.3 kcal/mol, respectively. Antioxidant studies demonstrated that both extracts displayed antioxidant effects in the DPPH<sup>•</sup>, ABTS<sup>•+</sup>, NO<sup>•</sup>, β-carotene-linoleic acid system, FRP, and TAC assays. Additionally, they provided significant protection to erythrocytes against H<sub>2</sub>O<sub>2</sub>-induced hemolysis. These findings, suggests that <em>L. nobilis</em> exhibits significant potential as a source of therapeutic agents for combating <em>T. gondii</em> infection and managing its associated adverse effects.</p></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142129783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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