{"title":"Radial motor nerve conduction study in posterior interosseous nerve syndrome and multifocal motor neuropathy.","authors":"José Pedro S Baima, Carlos Otto Heise","doi":"10.1055/s-0045-1806818","DOIUrl":"https://doi.org/10.1055/s-0045-1806818","url":null,"abstract":"<p><strong>Background: </strong> Finger extension weakness could be a presentation of either posterior interosseous nerve (PIN) syndrome or multifocal motor neuropathy (MMN). However, there is a delay in the diagnosis of MMN in cases with a selective radial weakness, as they are frequently misdiagnosed as PIN.</p><p><strong>Objective: </strong> To analyze which variables in nerve conduction studies could aid in the early diagnosis of MMN.</p><p><strong>Methods: </strong> We reviewed charts of patients with diagnoses of MMN or PIN syndrome, from 2014 to 2022, in a single Brazilian reference center. Electrophysiological parameters included in the analysis were motor conduction velocity (CV), the presence and magnitude of conduction block (CB), distal motor latencies (DML), and the compound muscle action potential amplitude (CMAP) of the affected radial nerve.</p><p><strong>Results: </strong> A total of 44 radial nerves were included in the study. Axonal loss was associated with a diagnosis of PIN syndrome, while conduction block was associated with MMN (<i>p</i> < 0.05). No patient with PIN had a CB over 60%, while 7 out of 12 radial CB blocks in patients with MMN were above that. Axonal degeneration was present in 4 MMN patients and in all patients with PIN syndrome. There was no difference in CV and DML between groups.</p><p><strong>Conclusion: </strong> The presence of CB or the absence of distal CMAP amplitude reduction should lead physicians to consider MMN, and a comprehensive nerve conduction study should be performed.</p>","PeriodicalId":8694,"journal":{"name":"Arquivos de neuro-psiquiatria","volume":"83 2","pages":"1-5"},"PeriodicalIF":1.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143952788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Autobiographical memory impairment in genetic generalized epilepsies: neurocognitive and pathophysiological determinants.","authors":"Panayiotis Patrikelis, Eleni Loukopoulou, Elvira Masoura, Vasiliki Folia, Grigoris Kiosseoglou, Lambros Messinis, Sonia Malefaki, Giuliana Lucci, Vasileios Kimiskidis","doi":"10.1055/s-0045-1804923","DOIUrl":"10.1055/s-0045-1804923","url":null,"abstract":"<p><p>The neuropsychological breakdowns of autobiographical memory (AM) in adults suffering from genetic generalized epilepsy (GGE) are far from being understood and largely neglected.We aimed at identifying AM impairments in GGE by analyzing neurocognitive deficits in illness-related variables possibly affecting AM.Patients with GGE were compared to healthy controls (HCs), through semistructured interviews on AM, as well as neuropsychological measures to identify potential determinants of AM impairment.A single GGE group was formed by including patients with juvenile myoclonic epilepsy (JME), juvenile absence epilepsy (JAE), and epilepsy with generalized tonic-clonic seizures alone (EGTCA). Both GGE patients and HCs were tested for differential impairments in autobiographical episodic memory (AEM) and/or autobiographical semantic memory (ASEM), as well as other episodic- and/or semantic-memory and executive-function domains.The GGE patients exhibited overall impairment in autobiographical episodic and semantic information retrieval compared to HCs, both regarding childhood and the recent past. Furthermore, GGE patients demonstrated significantly poorer performance in immediate and delayed episodic recall, visuospatial working memory, visuoperceptual organization, face recognition memory, and verbal-executive functions compared to HCs. A distinct visuoperceptual involvement in retrieving childhood autobiographical episodic and semantic information has emerged, suggesting a potential connection between the latter AM systems and visual cognition.</p>","PeriodicalId":8694,"journal":{"name":"Arquivos de neuro-psiquiatria","volume":"83 2","pages":"1-10"},"PeriodicalIF":1.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Renato Canevari Dutra da Silva, Anderson Garcez, Adriana Vieira Macedo Brugnoli, Marcos Pascoal Pattussi, Maria Teresa Anselmo Olinto
{"title":"Psychometric properties of the Epworth Sleepiness Scale in Brazilian medical students.","authors":"Renato Canevari Dutra da Silva, Anderson Garcez, Adriana Vieira Macedo Brugnoli, Marcos Pascoal Pattussi, Maria Teresa Anselmo Olinto","doi":"10.1055/s-0045-1804921","DOIUrl":"10.1055/s-0045-1804921","url":null,"abstract":"<p><strong>Background: </strong> Excessive daytime sleepiness (EDS) refers to the propensity to become drowsy or fall asleep when the intention and expectation would be to stay awake, and the Epworth Sleepiness Scale (ESS) is an easy-to-apply instrument that can be used to assess the presence of EDS.</p><p><strong>Objective: </strong> To evaluate the psychometric properties of the ESS, including its construct validity and internal consistency, in a population of university students.</p><p><strong>Methods: </strong> Two samples of 400 students from the medicine program of a university located in the Midwest of Brazil were randomly selected from a cross-sectional academic study conducted in 2018. Construct validity was examined through exploratory and confirmatory factor analysis of the eight items of the ESS, and the internal consistency was evaluated using the Cronbach's α coefficient (α).</p><p><strong>Results: </strong> It was found that factor analyses revealed better adjustment measures when considering the ESS to be two-dimensional, grouped into two main factors: the first factor referring to the evaluation of sleepiness at rest, and the second referring to drowsiness in activity (standardized root mean square residual [SRMR] = 0.053; root mean square error of approximation [RMSEA] = 0.095; Comparative Fit Index [CFI] = 0.937; and Tucker-Lewis Index [TLI] = 0.908; <i>p</i> < 0.05). Moreover, the ESS presented an adequate internal consistency (α = 0.75).</p><p><strong>Conclusion: </strong> The present study showed general psychometric properties adequate for the ESS in medical students, including an acceptable construct validity and internal consistency. Thus, the ESS may be suitable to assess EDS in university students, especially medical students.</p>","PeriodicalId":8694,"journal":{"name":"Arquivos de neuro-psiquiatria","volume":"83 2","pages":"1-6"},"PeriodicalIF":1.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giovanni Batista Palma, Mariana Drummond Martins Lima, Ana Carolina Oliveira Rodrigues, Clarisse Vasconcelos Friedlaender, Celso Furtado de Azevedo Filho, Rodrigo Campos Pace Lasmar, Paulo Caramelli
{"title":"Cognitive functioning and soccer heading: one-year longitudinal assessment among professional players.","authors":"Giovanni Batista Palma, Mariana Drummond Martins Lima, Ana Carolina Oliveira Rodrigues, Clarisse Vasconcelos Friedlaender, Celso Furtado de Azevedo Filho, Rodrigo Campos Pace Lasmar, Paulo Caramelli","doi":"10.1055/s-0045-1805051","DOIUrl":"10.1055/s-0045-1805051","url":null,"abstract":"<p><strong>Background: </strong> Soccer is the most popular sport worldwide, and the only one in which players purposely and repetitively use their head to hit the ball. In recent years, more attention has been given to subconcussive impacts, which are characterized by a cranial impact that does not result in known or diagnosed concussion on clinical grounds.</p><p><strong>Objective: </strong> To investigate the effects of soccer heading on cognitive functioning among professional soccer players.</p><p><strong>Methods: </strong> In a longitudinal case-control study, 22 professional soccer players were compared with 37 non-athletes on 2 occasions (T0 and T1) separated by a 1-year interval. The cognitive assessment consisted of computerized neuropsychological tests and the Brief Neuropsychological Assessment Battery (NEUPSILIN).</p><p><strong>Results: </strong> There was no evidence of cognitive impairment among athletes, who actually outperformed the controls in terms of score, accuracy, and reaction time in certain tests. Moreover, the estimates of heading exposure did not correlate with the cognitive performance of players. The intragroup analyses revealed that while the controls improved their performance on three cognitive variables from T0 to T1, no improvement occurred among players. However, within-group variation in performance from T0 to T1 was similar.</p><p><strong>Conclusion: </strong> Although the present study has not shown an association between soccer heading and cognitive impairment, subconcussive impacts may have a negative effect on brain function, as improvement in cognitive performance was not observed among athletes. Future and longer longitudinal investigations are needed to clarify the relationship between soccer heading and cognition.</p>","PeriodicalId":8694,"journal":{"name":"Arquivos de neuro-psiquiatria","volume":"83 2","pages":"1-7"},"PeriodicalIF":1.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sixty years of the first studies by Horácio Martins Canelas on Wilson's disease.","authors":"Egberto Reis Barbosa, Jacy Bezerra Parmera, Rubens Gisbert Cury, Eduardo Luiz Rachid Cançado, Patrícia Áurea Andreucci Martins Bonilha, Hélio Afonso Ghizoni Teive","doi":"10.1055/s-0045-1802553","DOIUrl":"10.1055/s-0045-1802553","url":null,"abstract":"<p><p>Research into Wilson's disease (WD) in Brazil had the effective participation of Professor Horácio Martins Canelas, from the Neurologic Clinic of the Teaching Hospital of the School of Medicine of Universidade de São Paulo (USP). His exponential contributions to the study of WD placed Brazil on the international stage, making USP's Neurologic Clinic one of the world's leading research centers in the area of neurodegenerative diseases with metal accumulation.</p>","PeriodicalId":8694,"journal":{"name":"Arquivos de neuro-psiquiatria","volume":"83 2","pages":"1-3"},"PeriodicalIF":1.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143490490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Heading the ball, why does the neurologist need to know about it?","authors":"Renato Anghinah","doi":"10.1055/s-0045-1801864","DOIUrl":"https://doi.org/10.1055/s-0045-1801864","url":null,"abstract":"","PeriodicalId":8694,"journal":{"name":"Arquivos de neuro-psiquiatria","volume":"83 2","pages":"1"},"PeriodicalIF":1.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143596194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diogo Gonçalves Dos Santos Martins, Thiago Gonçalves Dos Santos Martins
{"title":"Comment on \"Stroke awareness in a Brazilian Northeastern capital city and the burden of the COVID-19 pandemic\".","authors":"Diogo Gonçalves Dos Santos Martins, Thiago Gonçalves Dos Santos Martins","doi":"10.1055/s-0045-1802310","DOIUrl":"https://doi.org/10.1055/s-0045-1802310","url":null,"abstract":"","PeriodicalId":8694,"journal":{"name":"Arquivos de neuro-psiquiatria","volume":"83 2","pages":"1-2"},"PeriodicalIF":1.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143188149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Professor Sérgio Augusto Pereira Novis (1940-2024).","authors":"Luiz Eduardo Novis, Maria Lúcia Vellutini Pimentel, Hélio Afonso Ghizoni Teive","doi":"10.1055/s-0045-1805050","DOIUrl":"https://doi.org/10.1055/s-0045-1805050","url":null,"abstract":"","PeriodicalId":8694,"journal":{"name":"Arquivos de neuro-psiquiatria","volume":"83 2","pages":"1-2"},"PeriodicalIF":1.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Letícia Januzi de Almeida Rocha, Monica Thalia de Brito Melo, Renata Girardi Piva, Samira Mercaldi Rafani, Octavio Marques Pontes-Neto, Eva Rocha, Jussara Almeida de Oliveira Baggio
{"title":"Reply to: Stroke awareness in a Brazilian Northeastern capital city and the burden of the COVID-19 pandemic.","authors":"Letícia Januzi de Almeida Rocha, Monica Thalia de Brito Melo, Renata Girardi Piva, Samira Mercaldi Rafani, Octavio Marques Pontes-Neto, Eva Rocha, Jussara Almeida de Oliveira Baggio","doi":"10.1055/s-0045-1806920","DOIUrl":"https://doi.org/10.1055/s-0045-1806920","url":null,"abstract":"","PeriodicalId":8694,"journal":{"name":"Arquivos de neuro-psiquiatria","volume":"83 2","pages":"1-2"},"PeriodicalIF":1.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143960458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shai Oisiovici Laks, Nathalia Volpato, Nikolas Coelho, Mateus Henrique Nogueira, Pamela Regina Henning, Aline de Fatima Dias, William Souza Martins Ferreira, Clarissa Lin Yasuda, Luciana Ramalho Pimentel-Silva, Fernando Cendes
{"title":"Aerobic physical exercise improves quality of life in temporal lobe epilepsy.","authors":"Shai Oisiovici Laks, Nathalia Volpato, Nikolas Coelho, Mateus Henrique Nogueira, Pamela Regina Henning, Aline de Fatima Dias, William Souza Martins Ferreira, Clarissa Lin Yasuda, Luciana Ramalho Pimentel-Silva, Fernando Cendes","doi":"10.1055/s-0045-1804919","DOIUrl":"10.1055/s-0045-1804919","url":null,"abstract":"<p><strong>Background: </strong> A prior study showed that people with temporal lobe epilepsy (TLE) with an active lifestyle present a better quality of life (QoL), but the influence of aerobic physical exercise (APE) in the QoL of these patients is still unclear. As pharmacoresistance is commonly associated with TLE, the possibility of seizures during the activities might prevent patients from benefiting from APE.</p><p><strong>Objective: </strong> To analyze the influence of APE in the QoL of TLE patients and also focus on the seizure worry subitem of the QoL in epilepsy 31 (QoLIE-31) questionnaire.</p><p><strong>Methods: </strong> We analyzed data from 25 individuals with TLE who participated in a 6-month APE program under the supervision of a board-certified physical trainer. TLE patients were divided into training (TLE-training) and control (TLE-control) groups. The TLE-training group underwent an APE program of 6 months, while the control group was oriented to keep their routine. We assessed all patients with the QoLIE-31 at baseline and after 6 months. We used a mixed-between-subjects ANOVA to assess the APE intervention compared with TLE-control pre- and postintervention on the QoL.</p><p><strong>Results: </strong> We found a significant interaction between intervention groups and APE-time (<i>p</i> = 0.0005), showing that only patients in the TLE-training group presented higher QoL after the intervention (<i>p</i> = 0.001). We found no significant differences between groups for seizure worry (<i>p</i> = 0.50).</p><p><strong>Conclusion: </strong> There was improvement in QoL due to APE, with no increase in seizure worry, which might be a feature of concern for both patients and healthcare practitioners. Further studies should focus on long-term interventions to evaluate the impact of APE in QoL.</p>","PeriodicalId":8694,"journal":{"name":"Arquivos de neuro-psiquiatria","volume":"83 2","pages":"1-5"},"PeriodicalIF":1.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}