Arquivos de neuro-psiquiatria最新文献

Krabbe disease: a differential cause of the hyperdense boomerang sign. 蟹黄病：高密度回巢征的鉴别病因。

IF 1.6 4区医学

Arquivos de neuro-psiquiatria Pub Date : 2025-12-01 Epub Date: 2025-08-04 DOI: 10.1055/s-0045-1809997

Luis Alcides Quevedo Canete, Sérgio Ferreira Alves Júnior, Ângelo Dante de Carvalho Côrrea, Nina Ventura

引用次数: 0

When the brain fades before the eye: encephalopathy as a rare presentation of direct carotid-cavernous fistula. 当大脑在眼前消失：脑病作为一种罕见的直接颈动脉-海绵状瘘的表现。

IF 1 4区医学

Arquivos de neuro-psiquiatria Pub Date : 2025-12-01 Epub Date: 2025-07-15 DOI: 10.1055/s-0045-1809932

Leonardo Furtado Freitas, Eduardo J Labat, Robert T Wicks, Charif Sidani, Kevin J Abrams

引用次数: 0

Double calcification in PLNTY: an unusual presentation of a rare tumor in young patients. PLNTY双钙化：年轻患者罕见肿瘤的不寻常表现。

IF 1.6 4区医学

Arquivos de neuro-psiquiatria Pub Date : 2025-11-01 Epub Date: 2025-07-28 DOI: 10.1055/s-0045-1809933

Diego Jordão Lino Dias, Camilla Akemi Felizardo Yamada, Carmen Lucia Penteado Lancellotti, Lázaro Luíz Faria do Amaral

引用次数: 0

Isolated complete oculomotor nerve palsy as a presentation of adult medulloblastoma. 成人成神经管细胞瘤表现为孤立的完全动眼神经麻痹。

IF 1.6 4区医学

Arquivos de neuro-psiquiatria Pub Date : 2025-10-01 Epub Date: 2025-07-01 DOI: 10.1055/s-0045-1809883

Rafael Tuzino Leite Neves Maffei, Bruna Gutierres Gambirasio, Murillo Silva Catito, Sebastião Boanerges de Araujo Neto, Adrialdo José Santos

引用次数: 0

Calcitonin gene-related peptide monoclonal antibodies and medication overuse headache: is stopping excessive pain medication still necessary? 降钙素基因相关肽单克隆抗体与药物过度使用性头痛：是否仍有必要停止使用过量止痛药？

IF 1.6 4区医学

Arquivos de neuro-psiquiatria Pub Date : 2025-09-01 Epub Date: 2025-07-28 DOI: 10.1055/s-0045-1809658

João José Freitas de Carvalho

{"title":"Calcitonin gene-related peptide monoclonal antibodies and medication overuse headache: is stopping excessive pain medication still necessary?","authors":"João José Freitas de Carvalho","doi":"10.1055/s-0045-1809658","DOIUrl":"10.1055/s-0045-1809658","url":null,"abstract":"Recent studies demonstrate a significant paradigm shift concerning migraine patients suffering from medication overuse (MO). Traditionally, doctors used to demand that patients who overused medications be withdrawn before beginning any preventive therapy; however, such a belief has recently been challenged by emerging evidence about the benefit of calcitonin gene-related peptide monoclonal antibodies (CGRP mAbs), which have shown similar effectiveness in several clinical trials and real-world studies, regardless of whether a patient has previously stopped taking excessive medications. The data indicates that patients undergoing CGRP mAb therapy naturally decreased their acute medication consumption as migraine frequency diminished without requiring forced discontinuation. Furthermore, safety analyses have confirmed favorable tolerability profiles when CGRP mAbs are administered concurrently with various acute medications. This new evidence-based approach offers several clinical advantages, including enhanced treatment adherence and reduced risk of withdrawal complications. These findings support transitioning from mandatory detoxification protocols toward more individualized treatment strategies, representing a significant advancement in clinical migraine management.","PeriodicalId":8694,"journal":{"name":"Arquivos de neuro-psiquiatria","volume":"83 9","pages":"1-3"},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144726971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Translation and cross-cultural adaptation of a questionnaire for assessing hyperacusis in Williams syndrome. 威廉斯症候群听觉亢进评估问卷的翻译与跨文化改编。

IF 1.6 4区医学

Arquivos de neuro-psiquiatria Pub Date : 2025-09-01 Epub Date: 2025-09-08 DOI: 10.1055/s-0045-1811624

Jacqueline Aquino do Nascimento, Lucas Pinto Mielle, Liliane Aparecida Fagundes Silva, Alessandra Giannella Samelli, Carla Gentile Matas

{"title":"Translation and cross-cultural adaptation of a questionnaire for assessing hyperacusis in Williams syndrome.","authors":"Jacqueline Aquino do Nascimento, Lucas Pinto Mielle, Liliane Aparecida Fagundes Silva, Alessandra Giannella Samelli, Carla Gentile Matas","doi":"10.1055/s-0045-1811624","DOIUrl":"https://doi.org/10.1055/s-0045-1811624","url":null,"abstract":"Williams syndrome (WS) is a genetic, multisystemic, and neurodevelopmental disorder. The prevalence of auditory hypersensitivity in WS is high, especially in childhood, with reports in the literature from 94 to 100% of individuals evaluated, which can generate significant impacts on their quality of life. Therefore, the existence of instruments for screening hyperacusis that are easy and quick to apply for use in clinical routine is essential.To translate and perform the cross-cultural adaptation of the Hyperacusis Screening Questionnaire into Brazilian Portuguese.A questionnaire concerning auditory hypersensitivity in WS was translated by two translators who are fluent in English. After the synthesis of the translations, back-translation was performed to analyze similarity, a meeting of the expert committee for semantic and linguistic adaptation of the instrument was held, and pretesting and validation of content and appearance was conducted.The translated and adapted version of the questionnaire was similar to the original regarding general and referential meaning. Answers from 324 families of individuals with WS were included, 85.2% of those reported hyperacusis as a ongoing symptom.The translation and cross-cultural adaptation of the questionnaire were performed according to the methodology recommended in the literature, with necessary equivalences being made for the Brazilian reality. The instrument developed and tested in the present study proved to be useful in screening for hyperacusis in the population with WS, allowing its use in future investigations on the subject and comparison with other studies.","PeriodicalId":8694,"journal":{"name":"Arquivos de neuro-psiquiatria","volume":"83 9","pages":"1-6"},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145022789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In the era of monoclonal antibodies targeting the calcitonin gene-related peptide pathway, is it still necessary to stop taking excessive pain medication? 在靶向降钙素基因相关肽途径的单克隆抗体时代，是否还需要停止过量服用止痛药？

IF 1.6 4区医学

Arquivos de neuro-psiquiatria Pub Date : 2025-09-01 Epub Date: 2025-07-28 DOI: 10.1055/s-0045-1809333

Renata Gomes Londero

引用次数: 0

Cerebellar and extra-cerebellar symptoms in movement disorders. 运动障碍的小脑和小脑外症状。

IF 1.6 4区医学

Arquivos de neuro-psiquiatria Pub Date : 2025-09-01 Epub Date: 2025-09-19 DOI: 10.1055/s-0045-1811728

Dayany Leonel Boone, Victor Rebelo Procaci, Henrique Ballalai Ferraz, Orlando Graziani Povoas Barsottini, José Luiz Pedroso

引用次数: 0

Cerebellar syndromes: clinical observations leading to the recognition of the three types. 小脑综合征：辨证论治的临床观察。

IF 1.6 4区医学

Arquivos de neuro-psiquiatria Pub Date : 2025-09-01 Epub Date: 2025-09-19 DOI: 10.1055/s-0045-1811727

Mario Manto, Hiroshi Mitoma

{"title":"Cerebellar syndromes: clinical observations leading to the recognition of the three types.","authors":"Mario Manto, Hiroshi Mitoma","doi":"10.1055/s-0045-1811727","DOIUrl":"https://doi.org/10.1055/s-0045-1811727","url":null,"abstract":"Cerebellar syndrome is traditionally categorized into three primary types: cerebellar motor syndrome (CMS), vestibulocerebellar syndrome (VCS), and cerebellar cognitive affective syndrome (CCAS) or Schmahmann syndrome (SS). The first type is subdivided into five elemental features: dysmetria, kinetic tremor, asynergia, adiadochokinesis and dyschronometria. The second is characterized by dysmetria of saccades and jerky pursuit, as well as downbeat nystagmus and gaze-evoked nystagmus. And the third type is associated with a broader spectrum of cognitive and affective symptoms, including impairments in executive function, spatial cognition, language processing and emotional regulation. In its extreme form, cerebellar mutism can also develop during childhood following cerebellar vermis surgery. Recent physiological studies have shed light on the underlying neural mechanisms of these syndromes by identifying a common link of dysfunction within the cerebellum's internal forward model. This is essential to the prediction of the outcomes of motor and cognitive actions and underlines dysmetria as the core common element. Despite the diversity in clinical presentation, cerebellar syndromes can be understood as disruptions of a unified neural mechanism, providing a new framework for better understanding of cerebellar deficits.","PeriodicalId":8694,"journal":{"name":"Arquivos de neuro-psiquiatria","volume":"83 9","pages":"1-8"},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145091149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A cello concert in Brazilian lands: the life, art, and disease of Jacqueline du Pré. 巴西土地上的大提琴音乐会：杰奎琳·杜·普莱尔的生活、艺术和疾病。

IF 1.6 4区医学

Arquivos de neuro-psiquiatria Pub Date : 2025-09-01 Epub Date: 2025-09-19 DOI: 10.1055/s-0045-1811726

Diogo Haddad-Santos, Filipi Fim Andreão, Filipe Virgilio Ribeiro, Karlos Daniell Araújo Dos Santos, Fernanda Herculano, Guilherme Sciascia do Olival, Rafael Paterno Dias Carneiro

引用次数: 0