Arquivos de neuro-psiquiatria最新文献_第2页

Neurophysiology combined with sonography as a useful tool in median nerve leprosy diagnosis.

IF 1 4区医学

Arquivos de neuro-psiquiatria Pub Date : 2024-12-01 Epub Date: 2025-01-08 DOI: 10.1055/s-0044-1801743

Osvaldo J M Nascimento

引用次数: 0

Stroke in Brazil: prevalence, activity limitations, access to healthcare, and physiotherapeutic treatment.

IF 1 4区医学

Arquivos de neuro-psiquiatria Pub Date : 2024-12-01 Epub Date: 2024-12-20 DOI: 10.1055/s-0044-1792094

Luana Karoline Castro Silva, Cristian Douglas Dantas de Sousa, Ramon Távora Viana, Renata Viana Brígido de Moura Jucá, Johnnatas Mikael Lopes, Christina Danielli Coelho de Morais Faria, Shamyr Sulyvan de Castro, Lidiane Andrea Oliveira Lima

{"title":"Stroke in Brazil: prevalence, activity limitations, access to healthcare, and physiotherapeutic treatment.","authors":"Luana Karoline Castro Silva, Cristian Douglas Dantas de Sousa, Ramon Távora Viana, Renata Viana Brígido de Moura Jucá, Johnnatas Mikael Lopes, Christina Danielli Coelho de Morais Faria, Shamyr Sulyvan de Castro, Lidiane Andrea Oliveira Lima","doi":"10.1055/s-0044-1792094","DOIUrl":"https://doi.org/10.1055/s-0044-1792094","url":null,"abstract":"Background: Stroke remains a public health problem, reported as the third cause of disability. Among survivors, the ability to perform usual daily activities may be reduced, requiring rehabilitation.Objective: To investigate the prevalence of self-reported stroke, the accessibility of healthcare, and the degree and percentage of patients with limitations in usual activities who are unassisted by physiotherapeutic treatment in different regions of the country.Methods: This cross-sectional study was conducted using data from the 2019 National Health Survey. Participants aged 15 years or older from all five geographic regions of Brazil who reported a diagnosis of stroke were included. The data were analyzed using sample weighting and expressed as estimates along with a 95% confidence interval (CI).Results: The national prevalence of self-reported stroke in Brazil was 1.9% (95%CI 1.7-2.0), equivalent to 1,975 individuals with diagnosis. Of these, 50.2% reported limitations in their daily activities, and more than half (54.6%) had regular follow-ups with healthcare professionals. However, only 24.6% reported having access to rehabilitation, while 73.4% of individuals with activity limitations received no physiotherapeutic treatment.Conclusion: The prevalence of' self-reported stroke in the Brazilian population was 1.9%, with more than half experiencing limitations in their activities. While more than half of the stroke patients underwent follow-ups from a health professional, only ¼ of them reported having access to rehabilitation. Government interventions are necessary to ensure effective access to healthcare, including rehabilitation for the Brazilian population.","PeriodicalId":8694,"journal":{"name":"Arquivos de neuro-psiquiatria","volume":"82 12","pages":"1-11"},"PeriodicalIF":1.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142870676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multiple cerebral cavernomas in linear scleroderma: an unusual association. 线性硬皮病中的多发性脑海绵状瘤：一种不寻常的关联。

IF 1 4区医学

Arquivos de neuro-psiquiatria Pub Date : 2024-12-01 Epub Date: 2024-09-24 DOI: 10.1055/s-0044-1790574

Gabriela Rodrigues Tomaz, Maria Eduarda Slhessarenko Fraife Barreto, Rafael Tuzino Leite Neves Maffei, Renato Barradas Rodrigues, Sebastião Boanerges de Araujo Neto, Marianna Pinheiro Moraes de Moraes, José Luiz Pedroso, Orlando Graziani Povoas Barsottini

引用次数: 0

Rockstar hands: a complex pattern of hand dystonia in Wilson's disease. 摇滚明星之手：威尔逊氏病手部肌张力障碍的复杂模式。

IF 1 4区医学

Arquivos de neuro-psiquiatria Pub Date : 2024-12-01 Epub Date: 2024-10-02 DOI: 10.1055/s-0044-1790573

Luis Eduardo Borges de Macedo Zubko, Renata Cristine Alves, Francisco Manoel Branco Germiniani, Hélio Afonso Ghizoni Teive

引用次数: 0

Optic neuritis in demyelinating diseases: study of 38 cases. 脱髓鞘疾病中的视神经炎：对 38 个病例的研究。

IF 1 4区医学

Arquivos de neuro-psiquiatria Pub Date : 2024-12-01 Epub Date: 2024-12-15 DOI: 10.1055/s-0044-1792093

João Marcos Campos Ferreira, Cristiane Rebello Gomes de Souza Fontes, Carolina do Val Ferreira Ramos, Osvaldo J M Nascimento

{"title":"Optic neuritis in demyelinating diseases: study of 38 cases.","authors":"João Marcos Campos Ferreira, Cristiane Rebello Gomes de Souza Fontes, Carolina do Val Ferreira Ramos, Osvaldo J M Nascimento","doi":"10.1055/s-0044-1792093","DOIUrl":"https://doi.org/10.1055/s-0044-1792093","url":null,"abstract":"Background: Optic neuritis is an inflammation of the optic nerve caused by genetic factors, external influences, and the activation of cross-reactive immune responses to infections.Objective: To describe the clinical and epidemiological characteristics of patients presenting optic neuritis as the initial symptom of some demyelinating diseases, divided among multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and myelin oligodendrocyte glycoprotein-immunoglobulin G (MOG-IgG)-associated disorders (MOGADs).Methods: Thirty-eight patients who had optic neuritis as their first symptom and later developed MS, NMOSD, or MOGADs were analyzed.Results: There were thirty-four female patients (90%) and 4 male patients (10%); 23 (60%) were white and 15 (40%) were black. The most frequent definitive diagnosis was MS, with 24 (63%) cases, followed by NMOSD with 12 (32%) cases, and MOGADs with 2 (5%) cases. Regarding age, 9 (24%) were under 20 years old, 19 (50%) were between 20 and 30 years old, 6 (21%) were between 31 and 40 years old, and 2 (5%) were over 41 years old. As for the time to diagnosis, MS required 54 months in the public sector and 12 months in the private sector. Neuromyelitis optica spectrum disorder took 108 months in the private sector and 14.5 months in the public sector, while MOGADs averaged 2 months in the private sector.Conclusion: Patients with optic neuritis as the initial symptom were predominantly female, aged between 21 and 40 years, and of predominantly white ethnicity, with a higher prevalence of MS. Additionally, a direct relationship between the healthcare sector and the time to diagnosis became evident.","PeriodicalId":8694,"journal":{"name":"Arquivos de neuro-psiquiatria","volume":"82 12","pages":"1-7"},"PeriodicalIF":1.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142827291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A self-reported Brazilian registry of 5q-spinal muscular atrophy: data on natural history, genetic characteristics, and multidisciplinary care.

IF 1 4区医学

Arquivos de neuro-psiquiatria Pub Date : 2024-12-01 Epub Date: 2024-12-20 DOI: 10.1055/s-0044-1792096

Rodrigo Holanda Mendonça, Juliane Suellen Arndt de Godoi, Edmar Zanoteli

{"title":"A self-reported Brazilian registry of 5q-spinal muscular atrophy: data on natural history, genetic characteristics, and multidisciplinary care.","authors":"Rodrigo Holanda Mendonça, Juliane Suellen Arndt de Godoi, Edmar Zanoteli","doi":"10.1055/s-0044-1792096","DOIUrl":"https://doi.org/10.1055/s-0044-1792096","url":null,"abstract":"Background: Spinal muscular atrophy linked to chromosome 5q (SMA-5q) is a neurodegenerative disorder caused by mutations in the SMN1 gene.Objective: To describe the key demographic, clinical and genetic characteristics, as well as natural history data of patients with SMA-5q.Methods: Up to January 2022, 706 patients with confirmed genetic diagnosis of SMA-5q, or their parents, completed a self-reported questionnaire on natural history, genetic characteristics, drug treatments, and multidisciplinary care.Results: Most patients had type 1 SMA-5q (42%); with 33% having type 2, and 23% type 3. There were 667 patients (94.4%) with a homozygous SMN1-exon 7 deletion. Of the total, 131 (18.6%) patients had a previous family history of the disease, and the familial recurrence rate was higher in type 3 (25.6%). Type 1 patients had a mean age of 3 months at the onset of symptoms and a delay of more than 3 months until genetic diagnosis. The median survival of patients with type 1 without invasive ventilation was 27 months. Before 2018, the median age of use of invasive ventilation was 16 months and, after, most patients (71%) were not submitted to invasive ventilation. About 50% of patients with type 3 lost their walking ability by 37 years of age. Further, 384 (54.4%) patients had access to disease-modifying therapy, and 62.3% of type 1 patients were in treatment, compared with only 47.2% of type 2 and 31.9% of type 3 patients.Conclusion: There is still a substantial diagnostic delay, especially in those patients with types 2 and 3 SMA-5q. However, the present study demonstrated prolonged survival, especially in type 1 patients.","PeriodicalId":8694,"journal":{"name":"Arquivos de neuro-psiquiatria","volume":"82 12","pages":"1-9"},"PeriodicalIF":1.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142871275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Complex movement disorders in early onset hypoparathyroidism. 早发性甲状旁腺功能减退症的复杂运动障碍

IF 1 4区医学

Arquivos de neuro-psiquiatria Pub Date : 2024-12-01 Epub Date: 2024-09-04 DOI: 10.1055/s-0044-1788778

Filipe Sarmento, João Vitor Gerdulli Tamanini, Sofia Mônaco Gama, Leonardo Furtado Freitas, Orlando Graziani Povoas Barsottini, José Luiz Pedroso

引用次数: 0

Recent advances in autoimmune encephalitis.

IF 1 4区医学

Arquivos de neuro-psiquiatria Pub Date : 2024-12-01 Epub Date: 2024-12-20 DOI: 10.1055/s-0044-1793933

João Henrique Fregadolli Ferreira, Caio César Diniz Disserol, Bruna de Freitas Dias, Alexandre Coelho Marques, Marina Driemeier Cardoso, Pedro Victor de Castro Silva, Fabio Fieni Toso, Lívia Almeida Dutra

{"title":"Recent advances in autoimmune encephalitis.","authors":"João Henrique Fregadolli Ferreira, Caio César Diniz Disserol, Bruna de Freitas Dias, Alexandre Coelho Marques, Marina Driemeier Cardoso, Pedro Victor de Castro Silva, Fabio Fieni Toso, Lívia Almeida Dutra","doi":"10.1055/s-0044-1793933","DOIUrl":"https://doi.org/10.1055/s-0044-1793933","url":null,"abstract":"Since the description of autoimmune encephalitis (AE) associated with N-methyl-D-aspartate receptor antibodies (anti-NMDARE) in 2007, more than 12 other clinical syndromes and antibodies have been reported. In this article, we review recent advances in pathophysiology, genetics, diagnosis pitfalls, and clinical phenotypes of AE associated with cell surface antibodies and anti-GAD associated neurological syndromes. Genetic studies reported human leukocyte antigen (HLA) associations for anti-LGI1, anti-Caspr2, anti-IgLON5, and anti-GAD. Follow-up studies characterized cognitive dysfunction, psychiatric symptoms, sleep disorders, and adaptative behavior dysfunction, mainly for anti-NMDARE. Late-onset anti-NMDARE and anti- GABA-B receptor (GABA-BR) encephalitis patients were described to have worse prognoses and different tumor associations. Additionally, the clinical spectrum of anti-LGI1, anti-AMPAR, anti-CASPR2, and anti-IgLON5 was expanded, comprising new differential diagnoses. The diagnostic criteria for AE were adapted to the pediatric population, and a diagnostic algorithm was proposed, considering potential mimics and misdiagnosis. We also review the limitations of commercial assays for AE and treatment recommendations, as well as clinical scales for short and long-term assessment of AE patients, along with cognitive evaluation.","PeriodicalId":8694,"journal":{"name":"Arquivos de neuro-psiquiatria","volume":"82 12","pages":"1-13"},"PeriodicalIF":1.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142870751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of lamina cribrosa thickness and hippocampal volume in Alzheimer's disease patients. 阿尔茨海默病患者的颅骨板厚度与海马体积的关系

IF 1 4区医学

Arquivos de neuro-psiquiatria Pub Date : 2024-11-01 Epub Date: 2024-11-03 DOI: 10.1055/s-0044-1791658

Ersin Kasım Ulusoy, Döndü Melek Ulusoy, Mehmet Fatih Göl, Ayşe Çiçek, Turgut Tursem Tokmak

{"title":"Association of lamina cribrosa thickness and hippocampal volume in Alzheimer's disease patients.","authors":"Ersin Kasım Ulusoy, Döndü Melek Ulusoy, Mehmet Fatih Göl, Ayşe Çiçek, Turgut Tursem Tokmak","doi":"10.1055/s-0044-1791658","DOIUrl":"10.1055/s-0044-1791658","url":null,"abstract":"Background: Alzheimer's disease (AD) is the most common cause of dementia and affects a large portion of the elderly population worldwide.Objective: To analyze the relationship between lamina cribrosa thickness (LCT) and hippocampal volume in patients with AD and mild cognitive impairment (MCI).Methods: The sample in the present study consisted of 20 recently diagnosed MCI patients, 20 recently diagnosed AD patients, and 20 matched healthy volunteers. Every patient underwent magnetic resonance imaging (MRI) scans. The VolBrain software (open-access platform for MRI brain analysis) was used to calculate the hippocampal volume. Optical coherence tomography was performed to measure the LCT. Analysis of variance and Pearson chi-squared tests were employed to assess the results.Results: The lowest total hippocampal volume (p < 0.05) was in the AD group, which was 6.14 ± 0.66 mm3, while in the control group, it was 7.7 ± 9.65 mm3, and 6.69 ± 0.46 mm3 in the MCI group. In comparison to the rest of the groups, in the AD group, the LCT was the thinnest (202.17 ± 16.35 µm). As per the results of the study population as a whole, low hippocampal volume causes low LCT, which shows an important relationship (r: 0.41; p < 0.05).Conclusion: The current findings present evidence of the relationship between hippocampal volume and LCT in patients with AD and MCI.","PeriodicalId":8694,"journal":{"name":"Arquivos de neuro-psiquiatria","volume":"82 11","pages":"1-7"},"PeriodicalIF":1.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11531867/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142567587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validation to Brazilian Portuguese of the coma recovery scale-revised. 根据巴西葡萄牙语验证昏迷恢复量表修订版。

IF 1 4区医学

Arquivos de neuro-psiquiatria Pub Date : 2024-11-01 Epub Date: 2024-11-20 DOI: 10.1055/s-0044-1791657

Ana Paula Silva Champs, Thayse Nayara Freitas do Vale Santanna, Christian Marques Couto, Roberta Correa Macedo, Patricia Sola Penna, Luciana Charchar Vilas Boas Cruz, Rafael Xavier da Silva-Neto, Luiz Sérgio Vaz

{"title":"Validation to Brazilian Portuguese of the coma recovery scale-revised.","authors":"Ana Paula Silva Champs, Thayse Nayara Freitas do Vale Santanna, Christian Marques Couto, Roberta Correa Macedo, Patricia Sola Penna, Luciana Charchar Vilas Boas Cruz, Rafael Xavier da Silva-Neto, Luiz Sérgio Vaz","doi":"10.1055/s-0044-1791657","DOIUrl":"10.1055/s-0044-1791657","url":null,"abstract":"Background: To improve the diagnostic accuracy of the state of consciousness of patients with severe brain injury, Giacino et al. introduced the Coma Recovery Scale (CRS) in 1991, which underwent revision in 2004, resulting in the revised CRS scale (CRS-R).Objective: To determine the concurrent validity, as well as inter- and intrarater agreement of the CRS-R's adaptation to Brazilian Portuguese.Methods: This study involved a sample of 30 patients with severe brain injury. Concurrent evaluations were also performed with the Glasgow Coma Scale (GCS) and the Full Outline of UnResponsiveness (FOUR) scale. A total of seven rehabilitation experts were recruited to assess the inter- and intrarater reliability agreement.Results: Interrater reliability was moderate to high for auditory, visual, motor, verbal, communication, and arousal subscales (Cohen weighted kappa = 0.765 to 0.892; p < 0.001). Significant inter and intrarater intraclass correlation coefficients were observed for the total CRS-R scores, all of which were statistically significant (p < 0.001). Also, total CRS-R scores exhibited a high correlation with the total GCS and FOUR scores, indicating acceptable concurrent validity (p < 0.001).Conclusion: The Brazilian Portuguese version of CRS-R can be reliably administered by trained examiners. This study demonstrated substantial to almost perfect interrater agreement for the total score and subscales, as well as high concurrent validity between the Brazilian Portuguese version of CRS-R and the other two standardized behavioral scales.","PeriodicalId":8694,"journal":{"name":"Arquivos de neuro-psiquiatria","volume":"82 11","pages":"1-8"},"PeriodicalIF":1.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11578665/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142680698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0