{"title":"Sectional Anatomy Quiz - IV","authors":"Adil Lathif, R. Hashmi","doi":"10.22038/AOJNMB.2019.38842.1260","DOIUrl":"https://doi.org/10.22038/AOJNMB.2019.38842.1260","url":null,"abstract":"In this series we present a quiz about identification of salient and important anatomical landmarks present at a given level on the computed tomography (CT) image. The representative image is followed by further images showing examples of various commonly encountered pathologies that can be seen at this level in clinical practice. Readers are expected to identify highlighted structures in all the images and appreciate how a given abnormality can alter the appearance of normal structures. The aim of this series is to foster understanding and interpretation of the CT component of the single photon emission computed tomography (SPECT) and positron emission tomography (PET) studies help nuclear physicians in interpretation by the nuclear medicine professionals.","PeriodicalId":8503,"journal":{"name":"Asia Oceania Journal of Nuclear Medicine and Biology","volume":"7 1","pages":"188 - 193"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68222764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammad Gharehdaghi, V. D. Dabbagh Kakhki, Alireza Khooei, Gholamhosein Novferesti, Alireza Hootkani, Mahdi Farzadnia, Ramin Sadeghi
{"title":"Is 99mTc-MIBI scintigraphy a predictor of response to pre-operative neoadjuvant chemotherapy in Osteosarcoma?","authors":"Mohammad Gharehdaghi, V. D. Dabbagh Kakhki, Alireza Khooei, Gholamhosein Novferesti, Alireza Hootkani, Mahdi Farzadnia, Ramin Sadeghi","doi":"10.7508/AOJNMB.2013.02.004","DOIUrl":"https://doi.org/10.7508/AOJNMB.2013.02.004","url":null,"abstract":"Objectives: Multidrug resistance (MDR), which may be due to the over expression of P-glycoprotein (Pgp) and/or MRP, is a major problem in neoadjuvant chemotherapy of osteosarcoma. The aim of this study was to investigate the role of Tc-99m MIBI scan for predicting the response to pre-operative chemotherapy. Methods: Twenty-five patients (12 males and 13 females, aged between 8 and 52y) with osteosarcoma were studied. Before the chemotherapy, planar 99mTc-MIBI anterior and posterior images were obtained 10-min [tumor-to-background ratio: (T1/B1)10min] and 3-hr after tracer injection. After completion of chemotherapy, again 99mTc-MIBI scan was performed at 10-min after tracer injection. In addition to calculation of decay corrected tumor to background (T/B) ratios, using the 10-min and 3-hr images of the pre-chemotherapy scintigraphy, percent wash-out rate (WR%) of 99mTc-MIBI was calculated. Using the 10-min images of the pre- and post-chemotherapy scans, the percent reduction in uptake at the tumor site after treatment (Red%) was also calculated. Then after surgical resection, tumor response was assessed by percentage of necrosis. Results: All patients showed significant 99mTc-MIBI uptake in early images. Only 9 patients showed good response to chemotherapy (necrosis≥90%) while 16 patients were considered as non-responder (necrosis<90%). There was no statistical significant difference between non-responders and responders in (T1/B1)10min.There was a significant negative correlation between WR% and percentage of necrosis (P=0.001). On the other hand, there was a significant correlation between Red% and percentage of necrosis (P<0.001).There was also statistical significant difference in WR% and Red% between non-responders and responders (both P< 0.001). Conclusion: Washout rate of 99mTc-MIBI in pre-chemotherapy scintigraphy as well as Red% using pre- and post-chemotherapy MIBI scintigraphy are useful methods for predicting response to neoadjuvant chemotherapy.","PeriodicalId":8503,"journal":{"name":"Asia Oceania Journal of Nuclear Medicine and Biology","volume":"26 1","pages":"22 - 27"},"PeriodicalIF":0.0,"publicationDate":"2013-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89479619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Asian Nuclear Medicine Board (ANMB); Why Do We Need It?","authors":"Sabih Durre","doi":"10.7508/AOJNMB.2013.02.001","DOIUrl":"https://doi.org/10.7508/AOJNMB.2013.02.001","url":null,"abstract":"Nuclear Medicine faces unique challenges in the 21st century as sophisticated equipment and radiotracers become available to define metabolic processes in ever more exquisite detail. These metabolic processes can be imaged and fused with conventional radiological techniques to provide a synthesis of anatomical and physiological information in the same image set. All of these exciting developments have led to the need of reorienting the very definition of nuclear medicine practice and the required knowledge of the nuclear medicine physician in this century. \u0000 \u0000In Asia, while some countries are at the forefront of nuclear medicine development, unfortunately there are even more countries which have not kept up with the times nor committed resources to start nuclear medicine (Table 1). There are also questions of “ownership” of the science and art of nuclear medicine and battle lines are being drawn for a turf war in many places. The author has maintained, for over two decades, the urgent need for strengthening nuclear medicine training programs (1). This perception is now shared by many others who believe that the “market acceptance” of the current generation of nuclear medicine physicians depends on broadening the knowledge base by a greater emphasis on complimentary imaging (and therapy) in training programs. In fact, even dual certification is held desirable, if not needed (2). The UK has already started an ambitious program that ensures cross training in radiology and internal medicine for those who opt for the nuclear medicine specialization pathway (3). In addition to all of these, in Asia there are additional issues of standardization in nuclear medicine training, comparable competence and competency/deficiencies (4). Designing a national training program for any country in Asia has challenges that are compounded by varying organizational healthcare structures, needs, material resources and geopolitical stability. Governmental commitment to healthcare varies not only in terms of dollars per person, or percentage of GDP but also in priorities to the extent that in same places nuclear medicine and modern imaging have been relegated to the “nice-to-have” category of facilities rather than “must-have” services (5). \u0000 \u0000 \u0000 \u0000Table 1 \u0000 \u0000Nuclear Medicine Practice and Training in Selected ARCCNM* Member States \u0000 \u0000 \u0000 \u0000The Asian Regional Cooperative Council for Nuclear Medicine (ARCCNM), as a body committed to promoting nuclear medicine knowledge in Asia, particularly in developing and less developed countries, has been cognizant of this heterogeneity in the practice and training of nuclear medicine in Asia. The organization has risen to the challenge by establishing an Asian Nuclear Medicine Board (ANMB) that seeks: \u0000 \u0000 \u0000 \u0000 \u0000 \u0000To address growing concerns on the inhomogeneity of training & practice of Nuclear Medicine in Asia. \u0000 \u0000 \u0000To strengthen training programs by developing curriculum of appropriate content that integrates the radiological sciences in","PeriodicalId":8503,"journal":{"name":"Asia Oceania Journal of Nuclear Medicine and Biology","volume":"67 1","pages":"1 - 3"},"PeriodicalIF":0.0,"publicationDate":"2013-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83292793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}