Asia Oceania Journal of Nuclear Medicine and Biology最新文献_第7页

Asia Oceania Journal of Nuclear Medicine and Biology Pub Date : 2022-01-01 DOI: 10.22038/AOJNMB.2021.55113.1381

Nina Li, Rashid Hashmi

引用次数: 0

Incidentally Detected Celiac Disease with Splenomegaly on ¹⁸F FDG PET/CT: A Potential Lymphoma Mimic. 偶然发现乳糜泻伴脾肿大的18F FDG PET/CT:潜在的淋巴瘤模拟。

Asia Oceania Journal of Nuclear Medicine and Biology Pub Date : 2021-01-01 DOI: 10.22038/AOJNMB.2020.49000.1333

Ananya Panda, Michael R McCarthy, Joseph A Murray, Rosalind F Sharain, Min Shi, Ayse Tuba Kendi

{"title":"Incidentally Detected Celiac Disease with Splenomegaly on 18F FDG PET/CT: A Potential Lymphoma Mimic.","authors":"Ananya Panda, Michael R McCarthy, Joseph A Murray, Rosalind F Sharain, Min Shi, Ayse Tuba Kendi","doi":"10.22038/AOJNMB.2020.49000.1333","DOIUrl":"https://doi.org/10.22038/AOJNMB.2020.49000.1333","url":null,"abstract":"Celiac disease is an immune-mediated disorder triggered by hypersensitivity to gluten occurring in genetically susceptible individuals. A high-index of suspicion is needed for diagnosis as patients can be asymptomatic or present with atypical symptoms or extra-intestinal manifestations. Typical 18F-Fluorodeoxyglucose (FDG) Positron Emission Tomography (PET)/Computed Tomography (CT) gastrointestinal manifestations of celiac disease include increased multifocal or diffuse jejunal and ileal uptake; focal duodenal uptake is less common. Splenomegaly with increased splenic FDG uptake is also uncommon in celiac disease in the absence of portal hypertension; small-sized spleen and functional hyposplenism are more typical. We report a case of celiac disease diagnosed after PET/CT showed FDG uptake in the duodenum and enlarged spleen. Follow-up after gluten-free diet showed complete metabolic resolution and regression of splenomegaly. The combination of focal bowel and splenic uptake is unusual in celiac disease and may be mistaken for a lymphoproliferative disorder. Awareness of this entity may avoid misdiagnosis and guide appropriate management.","PeriodicalId":8503,"journal":{"name":"Asia Oceania Journal of Nuclear Medicine and Biology","volume":"9 1","pages":"51-55"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701229/pdf/AOJNMB-9-51.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38776327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Orbital and brain metastases on ⁶⁸Ga-PSMA PET/CT in a patient with prostate carcinoma refractory to ¹⁷⁷Lu-PSMA and ²²⁵Ac-PSMA therapy. 对177Lu-PSMA和225Ac-PSMA治疗难治性前列腺癌患者的68Ga-PSMA PET/CT显示眼眶和脑转移。

Asia Oceania Journal of Nuclear Medicine and Biology Pub Date : 2021-01-01 DOI: 10.22038/AOJNMB.2020.50820.1347

Ashwin Singh Parihar, Kunal Ramesh Chandekar, Harpreet Singh, Ashwani Sood, Bhagwant Rai Mittal

{"title":"Orbital and brain metastases on 68Ga-PSMA PET/CT in a patient with prostate carcinoma refractory to 177Lu-PSMA and 225Ac-PSMA therapy.","authors":"Ashwin Singh Parihar, Kunal Ramesh Chandekar, Harpreet Singh, Ashwani Sood, Bhagwant Rai Mittal","doi":"10.22038/AOJNMB.2020.50820.1347","DOIUrl":"https://doi.org/10.22038/AOJNMB.2020.50820.1347","url":null,"abstract":"We present a case of metastatic prostate cancer with rare metastases involving the brain and orbit, in addition to liver, skeletal and nodal metastases. The patient had undergone prior hormonal therapy and chemotherapy and had disease progression despite 2 cycles of 177Lu-Prostate specific membrane antigen (177Lu-PSMA) based radioligand therapy. He had a partial response after 2 cycles of 225Ac-PSMA based targeted alpha therapy, as demonstrated on the 68Ga-PSMA PET/CT study. However, the patient had disease progression at the end of 4 cycles of 225Ac-PSMA therapy, evident by rising prostate specific antigen levels and imaging findings. The end of treatment 68Ga-PSMA PET/CT showed additional sites of metastases in the orbit and brain apart from overall disease progression. These are rare sites of distant spread in prostate cancer and require urgent evaluation and local treatment to prevent potential complications. The importance of detection of metastatic sites in closed cavities is because of the requirement for urgent intervention to avoid compression related complications.","PeriodicalId":8503,"journal":{"name":"Asia Oceania Journal of Nuclear Medicine and Biology","volume":"9 1","pages":"67-70"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701233/pdf/AOJNMB-9-67.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38776330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

A case of cardiac amyloidosis incidentally detected by bone scintigraphy. 骨显像偶然发现心脏淀粉样变1例。

Asia Oceania Journal of Nuclear Medicine and Biology Pub Date : 2021-01-01 DOI: 10.22038/AOJNMB.2020.50508.1350

Hiroki Tanaka, Makoto Hosono, Mitsunori Kanagaki, Marina Shimizu, Naoko Matsubara, Kazuna Kawabata, Tadashi Miyamoto, Kazumi Itoi

{"title":"A case of cardiac amyloidosis incidentally detected by bone scintigraphy.","authors":"Hiroki Tanaka, Makoto Hosono, Mitsunori Kanagaki, Marina Shimizu, Naoko Matsubara, Kazuna Kawabata, Tadashi Miyamoto, Kazumi Itoi","doi":"10.22038/AOJNMB.2020.50508.1350","DOIUrl":"https://doi.org/10.22038/AOJNMB.2020.50508.1350","url":null,"abstract":"A 73-year-old man with lung cancer underwent bone scintigraphy for disease staging. Diffuse myocardial technetium hydroxymethylene diphosphonate (99mTc-HMDP) uptake was incidentally found. A diagnosis of amyloid transthyretin (ATTR) cardiac amyloidosis was suspected, although the patient had no symptoms at this time. Single-photon emission computed tomography (SPECT) showed particularly strong uptake in the ventricular septum. Cardiac magnetic resonance imaging (CMR) showed widespread subendocardial and partly transmural enhancement of the left ventricular myocardium on delayed postcontrast T1-weighted images. These findings were consistent with ATTR cardiac amyloidosis. 18F-FDG uptake in the left ventricle wall was observed on PET/CT. He was finally diagnosed with ATTR by endomyocardial biopsy. There are two major subtypes of cardiac amyloidosis: ATTR amyloidosis and amyloid light-chain (AL) amyloidosis. Endomyocardial biopsy is the gold standard for diagnosis. Recently, however, several reports have shown that bone scintigraphy using a 99mTc-labelled bone-seeking agent can detect ATTR cardiac amyloidosis and differentiate it from AL amyloidosis. Bone scintigraphy may play an important role in the detection and differentiation of ATTR cardiac amyloidosis.","PeriodicalId":8503,"journal":{"name":"Asia Oceania Journal of Nuclear Medicine and Biology","volume":"9 1","pages":"71-75"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701224/pdf/AOJNMB-9-71.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38776331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Herpes zoster infection mimicking pelvic lymph node metastasis on FDG-PET/CT in a patient with cervical cancer. 宫颈癌患者带状疱疹感染模拟盆腔淋巴结转移的FDG-PET/CT表现。

Asia Oceania Journal of Nuclear Medicine and Biology Pub Date : 2021-01-01 DOI: 10.22038/AOJNMB.2021.55050.1378

Kazutaka Harashima, Shiro Watanabe, Nanase Okazaki, Daisuke Endo, Yuko Uchiyama, Fumi Kato, Kenji Hirata, Kohsuke Kudo

{"title":"Herpes zoster infection mimicking pelvic lymph node metastasis on FDG-PET/CT in a patient with cervical cancer.","authors":"Kazutaka Harashima, Shiro Watanabe, Nanase Okazaki, Daisuke Endo, Yuko Uchiyama, Fumi Kato, Kenji Hirata, Kohsuke Kudo","doi":"10.22038/AOJNMB.2021.55050.1378","DOIUrl":"https://doi.org/10.22038/AOJNMB.2021.55050.1378","url":null,"abstract":"Although 18F-fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) is an established method for the staging of malignancies, benign lesions (e.g, active inflammatory lesions) often show increased metabolic activity. Herpes zoster is the clinical manifestation of the activation and replication of dormant varicella-zoster virus (VZV) in individuals with decreased cell-mediated immunity. Although the diagnosis of herpes zoster is clinical, it is sometimes observed incidentally during imaging for another disease. We describe the case of a 67-year-old Japanese female patient diagnosed with cervical cancer in whom FDG-PET/CT revealed herpes zoster manifestations: hypermetabolic cutaneous lesions in the buttock and pelvic lymph node involvement. The resected lymph nodes showed no malignant lesions but revealed lymphoid follicle formation, probably related to viral infection. There has been no report comparing FDG-PET findings of lymph nodes with histologic findings; the present findings are compatible with a clinically VZV-induced inflammatory reaction in regional lymph nodes, which increased FDG accumulation. Active infection with VZV displays increased FDG uptake in regional lymph nodes and may lead to incorrect malignant disease management in oncology. Misdiagnoses can be avoided by a careful interpretation by experienced nuclear medicine physicians as well as proper clinical evaluation.","PeriodicalId":8503,"journal":{"name":"Asia Oceania Journal of Nuclear Medicine and Biology","volume":"9 2","pages":"183-187"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255524/pdf/AOJNMB-9-183.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39174984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Physiological FDG uptake in growth plate on pediatric PET. 儿童PET生长板上FDG的生理性摄取。

Asia Oceania Journal of Nuclear Medicine and Biology Pub Date : 2021-01-01 DOI: 10.22038/AOJNMB.2020.49638.1339

Tomoaki Otani, Yuji Nakamoto, Takayoshi Ishimori

{"title":"Physiological FDG uptake in growth plate on pediatric PET.","authors":"Tomoaki Otani, Yuji Nakamoto, Takayoshi Ishimori","doi":"10.22038/AOJNMB.2020.49638.1339","DOIUrl":"https://doi.org/10.22038/AOJNMB.2020.49638.1339","url":null,"abstract":"Objectives: 18F-Fluorodeoxyglucose (FDG) uptake in children is different from that in adults. Physiological accumulation is known to occur in growth plates, but the pattern of distribution has not been fully investigated. Our aim was to evaluate the metabolic activity of growth plates according to age and location.Methods: We retrospectively evaluated 89 PET/CT scans in 63 pediatric patients (male : female=25 : 38, range, 0-18 years). Patients were classified into four age groups (Group A: 0-2 years, Group B: 3-9 years, Group C: 10-14 years and Group D: 15-18 years). The maximum standardized uptake value (SUVmax) of the proximal and distal growth plates of the humerus, the forearm bones and the femur were measured. The SUVmax of each site and each age group were compared and statistically analyzed. We also examined the correlations between age and SUVmax.Results: As for the comparison of SUVmax in each location, the SUVmax was significantly higher in the distal femur than those in the other sites (p< 0.01). SUVmax in the distal humerus and the proximal forearm bones were significantly lower than those in the other sites (p< 0.01). In the distal femur, there was large variation in SUVmax, while in the distal humerus and the proximal forearm bones, there was small variation. As for the comparison of SUVmax in each age group, the SUVmax in group D tended to be lower than those in the other groups, but in the distal femur, there was no significant difference among each age group.Conclusion: Our data indicate that FDG uptake in growth plates varies depending on the site and age with remarkable uptake especially in the distal femur.","PeriodicalId":8503,"journal":{"name":"Asia Oceania Journal of Nuclear Medicine and Biology","volume":"9 1","pages":"15-20"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701234/pdf/AOJNMB-9-15.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39123959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Brain hypometabolism in rare genetic neurodegenerative disease: Niemann-Pick disease type C, spinocerebellar ataxia and Huntington disease assessed by FDG PET. FDG PET评估罕见遗传性神经退行性疾病的脑代谢低下:尼曼-匹克病C型、脊髓小脑性共济失调和亨廷顿病

Asia Oceania Journal of Nuclear Medicine and Biology Pub Date : 2021-01-01 DOI: 10.22038/AOJNMB.2020.52511.1362

Yung Hsiang Kao, Melissa Cheng, Dennis Velakoulis, Mark Walterfang, Dinesh Sivaratnam

{"title":"Brain hypometabolism in rare genetic neurodegenerative disease: Niemann-Pick disease type C, spinocerebellar ataxia and Huntington disease assessed by FDG PET.","authors":"Yung Hsiang Kao, Melissa Cheng, Dennis Velakoulis, Mark Walterfang, Dinesh Sivaratnam","doi":"10.22038/AOJNMB.2020.52511.1362","DOIUrl":"https://doi.org/10.22038/AOJNMB.2020.52511.1362","url":null,"abstract":"Brain metabolic imaging using 18F-fluorodeoxyglucose (FDG) Positron Emission Tomography (PET) with contemporaneous low-dose CT may be used to assess neurodegenerative diseases. In contrast to oncology whole-body FDG PET, qualitative assessment alone in brain FDG PET is subjective and vulnerable to visual interference due to high physiologic background activity. Therefore, mild changes in brain metabolism may be visually undetectable by qualitative interpretation alone, resulting in diagnostic inaccuracy. To overcome this, some institutions may employ an objective comparison to a normal reference database. To date, there is limited literature describing brain metabolic changes in rare genetic neurodegenerative diseases such as Niemann-Pick disease Type C, spinocerebellar ataxia and Huntington disease. In this case series, we illustrate the typical FDG PET findings in the cortex and deep grey matter for these rare diseases, utilising normal database comparison including three dimensional Stereotactic Surface Projection (3D-SSP) mapping. These comparisons can generate 3D-SSP maps where metabolic changes may be expressed in standard deviations from normal (z-score) and visually depicted in a scale of colours to improve diagnostic accuracy.","PeriodicalId":8503,"journal":{"name":"Asia Oceania Journal of Nuclear Medicine and Biology","volume":"9 2","pages":"167-172"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255525/pdf/AOJNMB-9-167.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39174980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Incidental Diagnosis of Multiple Paragangliomas by Ga-68 DOTANOC Positron Emission Tomography-Computed Tomography. Ga-68 DOTANOC正电子发射断层扫描-计算机断层扫描对多发副神经节瘤的偶然诊断。

Asia Oceania Journal of Nuclear Medicine and Biology Pub Date : 2021-01-01 DOI: 10.22038/AOJNMB.2021.17883

Vivek Kumar Saini, Akshay Kumar, Aftab Hasan Nazar, Manish Ora, Sanjay Gambhir

{"title":"Incidental Diagnosis of Multiple Paragangliomas by Ga-68 DOTANOC Positron Emission Tomography-Computed Tomography.","authors":"Vivek Kumar Saini, Akshay Kumar, Aftab Hasan Nazar, Manish Ora, Sanjay Gambhir","doi":"10.22038/AOJNMB.2021.17883","DOIUrl":"https://doi.org/10.22038/AOJNMB.2021.17883","url":null,"abstract":"A 65-year-old man presented with intermittent abdominal pain for three months. Abdominal ultrasonography revealed a mass in the body of the pancreas. Moreover, abdominal contrast-enhancing computed tomography revealed a homogenously enhancing mass in the body of the pancreas. Scan findings were in favor of the neuroendocrine tumor, and the serum chromogranin level was slightly raised (111.9 ng/ml, normal <98). He had no history of vomiting, jaundice, melena, hematemesis, constipation, diarrhea, weight gain, weight loss, loss of appetite, and fever. He also had no symptoms related to the excessive production of catecholamines, such as hypertension. The patient was referred for Ga-68 DOTANOC positron emission tomography-computed tomography (Ga-68 DOTANOC PET-CT) for further evaluation. The scan was done to rule out metastatic disease or other synchronous lesions to plan surgical excision. The Ga-68 DOTANOC PET-CT revealed a pancreatic lesion with no other abdominal lesions. We noted multiple tracer avid soft tissue lesions on both sides of the neck that were not diagnosed previously. This case report demonstrates a rare case with multiple paragangliomas diagnosed by the Ga-68 DOTANOC PET-CT. This finding could lead to changes in patient management.","PeriodicalId":8503,"journal":{"name":"Asia Oceania Journal of Nuclear Medicine and Biology","volume":"9 2","pages":"173-176"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255528/pdf/AOJNMB-9-173.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39174981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Incremental Value of FDG PET/CT in Aggressive High Grade B Cell lymphoma with TdT Expression. FDG PET/CT在TdT表达的侵袭性高级别B细胞淋巴瘤中的增量价值

Asia Oceania Journal of Nuclear Medicine and Biology Pub Date : 2021-01-01 DOI: 10.22038/AOJNMB.2020.48887.1332

Nikita Sampathirao, Indirani Muthukrishnan, Ann Kurian, Jaykanth Amalchandran, Asra Patel, Shema Mathew, Shelley Simon

{"title":"Incremental Value of FDG PET/CT in Aggressive High Grade B Cell lymphoma with TdT Expression.","authors":"Nikita Sampathirao, Indirani Muthukrishnan, Ann Kurian, Jaykanth Amalchandran, Asra Patel, Shema Mathew, Shelley Simon","doi":"10.22038/AOJNMB.2020.48887.1332","DOIUrl":"https://doi.org/10.22038/AOJNMB.2020.48887.1332","url":null,"abstract":"High-grade B-cell lymphoma, an aggressive form of Non-Hodgkin's Lymphoma, is known as a double or triple hit lymphoma based on the presence of MYC and BCL2 without or with BCL6 genetic rearrangements, respectively. It carries a poorer prognosis, compared to other variants of B-cell lymphoma, and its management also differs which requires more intensive chemotherapy in contrast to the routine regimen. Terminal deoxynucleotidyl transferase (TdT), a marker of immaturity is commonly expressed in B-cell lymphoblastic leukemia or lymphoma (B cell ALL) which is absent in mature forms of B-cell lymphoma. The TdT is expressed in high-grade B-cell lymphoma; therefore, it poses a classification and management dilemma, which should be accurately differentiated from B-cell ALL and mandates molecular analysis. Herein, we report a case of a 52-year-old female with biopsy reported as high-grade B-cell lymphoma with TdT expression. She was referred for Fluor-deoxyglucose (FDG) Positron Emission Tomography-Computed Tomography (PET/CT) scan for staging in the absence of molecular analysis for B-cell ALL. It was diagnosed as lymphoma on FDG PET/CT based on its characteristic findings of extensive extranodal involvement of multiple organs with no significant lymphadenopathy establishing the incremental value of FDG PET/CT scan, which helped the clinician to arrive at a conclusion.","PeriodicalId":8503,"journal":{"name":"Asia Oceania Journal of Nuclear Medicine and Biology","volume":"9 1","pages":"45-50"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701230/pdf/AOJNMB-9-45.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38776326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Soft tissue metastasis of the penis detected by copper-64 labeled prostate-specific membrane antigen positron emission tomography (⁶⁴Cu-PSMA PET/CT) in a patient with prostate cancer. 用铜-64标记前列腺特异性膜抗原正电子发射断层扫描(64Cu-PSMA PET/CT)检测1例前列腺癌患者阴茎软组织转移。

Asia Oceania Journal of Nuclear Medicine and Biology Pub Date : 2021-01-01 DOI: 10.22038/AOJNMB.2021.53922.1371

Cherin Farhan, Siroos Mirzaei

{"title":"Soft tissue metastasis of the penis detected by copper-64 labeled prostate-specific membrane antigen positron emission tomography (64Cu-PSMA PET/CT) in a patient with prostate cancer.","authors":"Cherin Farhan, Siroos Mirzaei","doi":"10.22038/AOJNMB.2021.53922.1371","DOIUrl":"https://doi.org/10.22038/AOJNMB.2021.53922.1371","url":null,"abstract":"Prostate cancer is considered to be the most common solid cancer affecting men worldwide and leading to a significant morbidity and mortality. Metastases are usually seen in bone or lymph nodes. For recurrent disease, PET imaging with 68Ga-PSMA-11 (also known as HBED-CC, Glu-urea-Lys(Ahx)-HBED-CC, and PSMA-HBED-CC) is widely used. However, preparation of 68Ga-PSMA ligand requires the presence of radiochemistry facilities and can therefore not be utilized in centers lacking such facilities. Recently, copper labeled prostate-specific membrane antigen positron emission tomography (64Cu-PSMA PET/CT) demonstrated promising results in patients with recurrent disease and in the primary staging of selected patients with progressive local disease. In the present case, a rare manifestation site of a metastatic lesion in a patient with advanced prostate cancer is detected by 64Cu-PSMA PET/CT.","PeriodicalId":8503,"journal":{"name":"Asia Oceania Journal of Nuclear Medicine and Biology","volume":"9 2","pages":"180-182"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255521/pdf/AOJNMB-9-180.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39174983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0