Asia Oceania Journal of Nuclear Medicine and Biology最新文献

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CT Attenuation correction and its impact on image quality of myocardial perfusion imaging in coronary artery disease: A systematic review. CT衰减校正及其对冠状动脉疾病心肌灌注成像图像质量的影响:系统综述。
Asia Oceania Journal of Nuclear Medicine and Biology Pub Date : 2021-01-01 DOI: 10.22038/AOJNMB.2020.50692.1346
Claire M Farrell, Jo-Anne Pinson, Amy M Dennett
{"title":"CT Attenuation correction and its impact on image quality of myocardial perfusion imaging in coronary artery disease: A systematic review.","authors":"Claire M Farrell,&nbsp;Jo-Anne Pinson,&nbsp;Amy M Dennett","doi":"10.22038/AOJNMB.2020.50692.1346","DOIUrl":"https://doi.org/10.22038/AOJNMB.2020.50692.1346","url":null,"abstract":"<p><p>Myocardial perfusion imaging is a non-invasive procedure that plays an integral role in the diagnosis and management of coronary artery disease. With the routine use of computerised tomography attenuation correction (CTAC) in myocardial perfusion imaging still under debate, the aim of this review was to determine the impact of CTAC on image quality in myocardial perfusion imaging. Medline, Embase and CINAHL were searched from the earliest available time until August 2019. Methodological quality was assessed using the Quality Assessment of Diagnostic Accuracy Studies version 2. Details pertaining to image quality and diagnostic accuracy were analysed, and results summarised descriptively. Three studies with 'unclear' risk of bias and low applicability concerns (1002 participants) from a yield of 2725 articles were identified. Two studies demonstrated an increase in image quality, and one study found no difference in image quality when using CTAC compared to no attenuation correction. Benefits of CTAC for improving image quality remain unclear. Given the potential exposure risk with the addition of CTAC, patient and clinician factors should inform decision making for use of CTAC in myocardial perfusion imaging for coronary artery disease.</p>","PeriodicalId":8503,"journal":{"name":"Asia Oceania Journal of Nuclear Medicine and Biology","volume":"9 1","pages":"31-38"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701231/pdf/AOJNMB-9-31.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39123961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Bowel visualization on the lymphoscintigraphy images of a bladder cancer patient due to inadvertent injection of the tracer in the rectal wall. 一名膀胱癌患者因不小心在直肠壁注射示踪剂而导致的淋巴显像显示。
Asia Oceania Journal of Nuclear Medicine and Biology Pub Date : 2021-01-01 DOI: 10.22038/AOJNMB.2021.54064.1370
Hamidreza Ghorbani, Leili Zarifmahmoudi, Ramin Sadeghi, Salman Soltani, Atena Aghaee
{"title":"Bowel visualization on the lymphoscintigraphy images of a bladder cancer patient due to inadvertent injection of the tracer in the rectal wall.","authors":"Hamidreza Ghorbani,&nbsp;Leili Zarifmahmoudi,&nbsp;Ramin Sadeghi,&nbsp;Salman Soltani,&nbsp;Atena Aghaee","doi":"10.22038/AOJNMB.2021.54064.1370","DOIUrl":"https://doi.org/10.22038/AOJNMB.2021.54064.1370","url":null,"abstract":"<p><p>The effectiveness of the sentinel lymph node mapping in patients with Urothelial carcinoma of the bladder is under investigation. Single photon emission computed tomography (SPECT/CT) and intraoperative sentinel node biopsy using gamma probe are performed to detect the exact location of the sentinel lymph node to be dissected during the surgery. In this case report, a 73-year old man with high grade urothelial carcinoma was referred to our nuclear medicine department for SPECT/CT, four hours after injection of the radiotracer through cystoscopy. SPECT/CT could not reveal any sentinel node; however, one sentinel lymph node was detected and harvested in the right external iliac region during surgery. SPECT/CT revealed unusual accumulation of tracer in large bowel which was due to severe adhesion of rectum and bladder, and inadvertent injection of the radiotracer into the rectal wall. During the sentinel lymph node procedure, the tracer should be injected with extreme caution and lymphoscintigraphy post injection may help detection of any injection failures.</p>","PeriodicalId":8503,"journal":{"name":"Asia Oceania Journal of Nuclear Medicine and Biology","volume":"9 2","pages":"177-179"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255522/pdf/AOJNMB-9-177.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39174982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Prospective Study on [68Ga]-PSMA PET/CT Imaging in Newly Diagnosed Intermediate- and High-Risk Prostate Cancer. [68Ga]- psma PET/CT在新诊断中高危前列腺癌中的前瞻性研究
Asia Oceania Journal of Nuclear Medicine and Biology Pub Date : 2021-01-01 DOI: 10.22038/AOJNMB.2020.52375.1358
Sara Harsini, Babak Fallahi, Najme Karamzade Ziarati, Ali Razi, Erfan Amini, Alireza Emami-Ardekani, Armaghan Fard-Esfahani, Mehdi Kardoust Parizi, Saeed Farzanehfar, Davood Beiki
{"title":"A Prospective Study on [<sup>68</sup>Ga]-PSMA PET/CT Imaging in Newly Diagnosed Intermediate- and High-Risk Prostate Cancer.","authors":"Sara Harsini,&nbsp;Babak Fallahi,&nbsp;Najme Karamzade Ziarati,&nbsp;Ali Razi,&nbsp;Erfan Amini,&nbsp;Alireza Emami-Ardekani,&nbsp;Armaghan Fard-Esfahani,&nbsp;Mehdi Kardoust Parizi,&nbsp;Saeed Farzanehfar,&nbsp;Davood Beiki","doi":"10.22038/AOJNMB.2020.52375.1358","DOIUrl":"https://doi.org/10.22038/AOJNMB.2020.52375.1358","url":null,"abstract":"<p><strong>Objectives: </strong>Prostate-specific membrane antigen (PSMA) ligand positron emission tomography/computed tomography (PET/CT) is an emerging modality to detect metastatic disease in patients with prostate cancer (PCa). This prospective study aimed to evaluate the role of [<sup>68</sup>Ga]-PSMA PET/CT in the initial workup of intermediate and high-risk PCa.</p><p><strong>Methods: </strong>Twenty-five patients with newly transrectal ultrasound biopsy-proven, untreated intermediate- and high-risk PCa (mean age, 68.5±6.2 years; range 55-83 years) were enrolled in this prospective study between September 2018 and June 2020 and underwent a [<sup>68</sup>Ga]-PSMA PET/CT examination. All images were analyzed both visually and semiquantitatively by measuring the maximum standardized uptake value (SUV<sub>max</sub>) of the primary prostatic tumor and metastatic lesions. The diagnostic sensitivity of [<sup>68</sup>Ga]-PSMA PET/CT for the diagnosis of PCa was established by histopathology as the reference standard. The associations between SUV<sub>max</sub> of the primary tumors and prostate-specific antigen (PSA) levels, Gleason scores (GSs), and metastatic extent of the disease were studied.</p><p><strong>Results: </strong>All patients had a positive [<sup>68</sup>Ga]-PSMA PET/CT exam. Seventeen patients (58%) showed [<sup>68</sup>Ga]-PSMA avidity in both prostate lobes and 8 (32%) had unilateral uptake. SUV<sub>max</sub> in the primary tumor significantly correlated with serum PSA values (r=0.57, P=0.003). PSMA PET/CT depicted regional lymph node metastases in 32% of patients, distant lymph node metastases in 20%, osseous metastases in 16% and pulmonary metastases in 8% of patients. Sixty percent of PSMA-positive bone metastases and 21.4% of intraprostatic tumoral lesions were missed on the contemporaneous bone scintigraphy and magnetic resonance imaging, respectively.</p><p><strong>Conclusion: </strong>[<sup>68</sup>Ga]-PSMA PET/CT shows promise as a valuable imaging modality with high diagnostic sensitivity in the setting of intermediate and high-risk PCa. Moreover, the SUV<sub>max</sub> of the primary tumor has a positive correlation with PSA levels at the time of the scan.</p>","PeriodicalId":8503,"journal":{"name":"Asia Oceania Journal of Nuclear Medicine and Biology","volume":"9 2","pages":"101-110"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255520/pdf/AOJNMB-9-101.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39175538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Estimation of the lower limits for feasible Ra-223 SPECT imaging: a Monte Carlo simulation study. 估计可行的Ra-223 SPECT成像的下限:蒙特卡罗模拟研究。
Asia Oceania Journal of Nuclear Medicine and Biology Pub Date : 2021-01-01 DOI: 10.22038/AOJNMB.2021.54386.1372
Akihiko Takahashi, Hibiki Ueno, Shingo Baba, Masayuki Sasaki
{"title":"Estimation of the lower limits for feasible Ra-223 SPECT imaging: a Monte Carlo simulation study.","authors":"Akihiko Takahashi,&nbsp;Hibiki Ueno,&nbsp;Shingo Baba,&nbsp;Masayuki Sasaki","doi":"10.22038/AOJNMB.2021.54386.1372","DOIUrl":"https://doi.org/10.22038/AOJNMB.2021.54386.1372","url":null,"abstract":"<p><strong>Objectives: </strong>Ra-223 is a promising radionuclide for the treatment of skeletal metastases in castration-resistant prostate cancer patients. This study aims to estimate the lower limits for feasible Ra-223 single-photon emission computerized tomography (SPECT) imaging using a Monte Carlo simulation study.</p><p><strong>Methods: </strong>The SPECT images were produced on a homemade code: the Monte Carlo simulation of electrons and photons for SPECT (MCEP-SPECT). The National Electrical Manufacturers Association (NEMA) phantom with six hot spheres of diameters of 37, 28, 22, 17, 13, and 10 mm installed inside, was used. The background activity concentration was 0.6 kBq/mL, and the ratios of hot concentrations to the background (<i>R</i> <sub>HB</sub>) were 25, 20, 15, 10, and 5. When <i>R</i> <sub>HB</sub> was 15, the background concentrations of 1.5, 0.9, 0.3, and 0.15 kBq/mL were also tested. The energy window was 84 keV±10%. The number of projections was 60/360°, and the acquisition time was 60 s per projection. Two kinds of collimators: middle-energy general-purpose (MEGP) and high-energy general-purpose (HEGP), were examined. The SPECT images were evaluated based on two quantitative indexes: contrast-to-noise ratio (CNR) for detectability and contrast recovery coefficient (CRC) for quantitative accuracy.</p><p><strong>Results: </strong>The CRC for the HEGP collimator was 35-40%, while the CRC for the MEGP collimator was 25-30%. The CNRs for the MEGP collimator were larger than those for the HEGP collimator. The CNRs of the hot spheres with diameters less than 22 mm were lower than 5.0 for both collimators, when <i>R</i> <sub>HB</sub> and the background concentration were 15 and 0.6 kBq/mL, respectively. Based on the obtained results, it was estimated that the lower limit of <i>R</i> <sub>HB</sub> for the detection of the hot sphere with a diameter of 37 mm would be approximately 20 if the background concentration is 0.05 kBq/mL.</p><p><strong>Conclusions: </strong>The MEGP collimator is superior in terms of detectability, while the HEGP collimator is superior in terms of quantitative accuracy. When the lesion size is small, the MEGP collimator may be favorable. Based on these results, the estimated lower limit of the activity concentration would be approximately 1 kBq/mL if the background concentration is 0.05 kBq/mL for a large lesion.</p>","PeriodicalId":8503,"journal":{"name":"Asia Oceania Journal of Nuclear Medicine and Biology","volume":"9 2","pages":"131-139"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255527/pdf/AOJNMB-9-131.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39175541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
18F-THK 5351 and 11C-PiB PET of the Thai normal brain template. 泰国正常脑模板的18F-THK 5351和11C-PiB PET。
Asia Oceania Journal of Nuclear Medicine and Biology Pub Date : 2021-01-01 DOI: 10.22038/AOJNMB.2020.49623.1338
Chanisa Chotipanich, Supaporn Kongthai, Anchisa Kunawudhi, Chetsadaporn Promteangtrong, Attapon Jantarato
{"title":"<sup>18</sup>F-THK 5351 and <sup>11</sup>C-PiB PET of the Thai normal brain template.","authors":"Chanisa Chotipanich,&nbsp;Supaporn Kongthai,&nbsp;Anchisa Kunawudhi,&nbsp;Chetsadaporn Promteangtrong,&nbsp;Attapon Jantarato","doi":"10.22038/AOJNMB.2020.49623.1338","DOIUrl":"https://doi.org/10.22038/AOJNMB.2020.49623.1338","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of the study was to create a local normal database brain template of Thai individuals for <sup>11</sup>C-Pittsburgh compound B (<sup>11</sup>C-PiB) and <sup>18</sup>F-THK 5351 depositions using statistical parametric mapping (SPM) software, and to validate and optimize the established specific brain template for use in clinical practice with a highly reliability and reproducibility.</p><p><strong>Methods: </strong>This prospective study was conducted in 24 healthy right-handed volunteers (13 men, 11 women; aged: 42-79 years) who underwent <sup>18</sup>F-THK 5351 and <sup>11</sup>C-PiB PET/CT scans. SPM was used for the <sup>18</sup>F-THK 5351 and <sup>11</sup>C-PiB PET/CT image analysis. All PET images were processed individually using Diffusion Tensor Image -Magnetic Resonance Imaging-weighted images (DTI-MRI images), which involved: (1) conversion of Digital Imaging and Communications in Medicine (DICOM) files into an analyzable file extension (.NIFTI) for statistical parametric mapping, (2) setting of the origin (the anterior commissure was used as the anatomical landmark), (3) re-alignment, (4) co-registration of PET with B0 (T1W) and DTI-MRI images, (5) normalization, and (6) normal verification using the Thai MRI standard. We then compared the normal PET template with the abnormal deposition area of different dementia syndromes, including Alzheimer's disease and progressive supranuclear palsy.</p><p><strong>Results: </strong>This method was able to differentiate cognitively normal from Alzheimer's disease and progressive supranuclear palsy subjects.</p><p><strong>Conclusions: </strong>This normal brain template was able to be integrated into clinical practice and research using PET analyses at our center.</p>","PeriodicalId":8503,"journal":{"name":"Asia Oceania Journal of Nuclear Medicine and Biology","volume":"9 1","pages":"21-30"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701232/pdf/AOJNMB-9-21.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39123960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Extensive Extranodal Involvement in a case of Non-Hodgkin's Lymphoma with sparing of lymph nodes and lymphatic organs. 非霍奇金淋巴瘤广泛淋巴结外受累并保留淋巴结和淋巴器官1例。
Asia Oceania Journal of Nuclear Medicine and Biology Pub Date : 2021-01-01 DOI: 10.22038/AOJNMB.2020.47774.1324
Vijay Singh, Akshay Kumar, Prakash Singh, Manish Ora, Sanjay Gambhir
{"title":"Extensive Extranodal Involvement in a case of Non-Hodgkin's Lymphoma with sparing of lymph nodes and lymphatic organs.","authors":"Vijay Singh,&nbsp;Akshay Kumar,&nbsp;Prakash Singh,&nbsp;Manish Ora,&nbsp;Sanjay Gambhir","doi":"10.22038/AOJNMB.2020.47774.1324","DOIUrl":"https://doi.org/10.22038/AOJNMB.2020.47774.1324","url":null,"abstract":"<p><p>Non-Hodgkin lymphoma (NHL) is a group of malignant lymphoproliferative disorders arising predominantly in the lymph nodes with various clinical and histological characteristics. At least 25% of NHL originates from tissues other than lymph nodes and sometimes even from sites that do not contain lymphoid tissue. These are referred to as primary extranodal lymphomas (pENLs). pENL is a universal diagnostic challenge to the clinicians and pathologists due to their varied clinical presentations, morphological mimicry, and molecular alterations. The GIT is the most common site of pENL followed by nasopharynx/oropharynx, testis, uterus/ovary, thyroid, and central nervous system. Long bones (tibia), maxillary sinus, skin, and paraspinal soft tissues are the other rare anatomic sites of pENL. We reported a case of a 60-year-old female presented with pain and mass in the pelvis region. <sup>18</sup>F-Fluorodeoxyglucose (<sup>18</sup>F-FDG) positron emission tomography (PET) and fused PET/CT was done, which revealed extensive extranodal involvement of the lung, bilateral kidneys, uterus, ovaries, bones, and muscles with no involvement of lymph nodes or lymphomatous organs. Extensive extranodal involvement with sparing of lymphomatous organ has not been reported earlier.</p>","PeriodicalId":8503,"journal":{"name":"Asia Oceania Journal of Nuclear Medicine and Biology","volume":"9 1","pages":"39-44"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701225/pdf/AOJNMB-9-39.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39123962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
The early years of nuclear medicine: A Retelling. 核医学的早期:重述。
Asia Oceania Journal of Nuclear Medicine and Biology Pub Date : 2021-01-01 DOI: 10.22038/aojnmb.2021.55514.1385
Jerry M Obaldo, Barbara E Hertz
{"title":"The early years of nuclear medicine: A Retelling.","authors":"Jerry M Obaldo,&nbsp;Barbara E Hertz","doi":"10.22038/aojnmb.2021.55514.1385","DOIUrl":"https://doi.org/10.22038/aojnmb.2021.55514.1385","url":null,"abstract":"<p><p>Nuclear medicine history has its share of captivating personalities, controversial claims, and forgotten pioneers. Publications and documents that came out relatively recently, provide us with new perspectives on its history. Primary sourced material might contradict some of the long-held beliefs of the reader who only has a casual familiarity with the events, including basics such as who discovered radioactivity. Because of the nature of the specialty, the importance of the contributions of colleagues in related fields, like physics and chemistry, cannot be overstated. Many of the important discoveries were marked by serendipity, but the pioneers must be given credit for having the necessary insights to interpret the new phenomena correctly, sometimes turning perceived \"failure\" into novel scientific principles. In addition, most of our pioneers had to deal with inadequate facilities and funding, religious and racial discrimination, and even misogynism. The early history of nuclear medicine is presented in this article as a series of its most interesting anecdotes, from the early work on radioactivity, to the conception of the tracer principle, until the development of radioactive iodine therapy.</p>","PeriodicalId":8503,"journal":{"name":"Asia Oceania Journal of Nuclear Medicine and Biology","volume":"9 2","pages":"207-219"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255519/pdf/AOJNMB-9-207.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39174920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Usefulness of respiratory-gated PET acquisition during delayed 18F-FDG PET/CT scanning for patients with liver metastases. 延迟18F-FDG PET/CT扫描中呼吸门控PET采集对肝转移患者的有用性
Asia Oceania Journal of Nuclear Medicine and Biology Pub Date : 2021-01-01 DOI: 10.22038/AOJNMB.2021.53427.1365
Shota Watanabe, Kohei Hanaoka, Hayato Kaida, Tomoko Hyodo, Minoru Yamada, Masakatsu Tsurusaki, Kazunari Ishii
{"title":"Usefulness of respiratory-gated PET acquisition during delayed <sup>18</sup>F-FDG PET/CT scanning for patients with liver metastases.","authors":"Shota Watanabe,&nbsp;Kohei Hanaoka,&nbsp;Hayato Kaida,&nbsp;Tomoko Hyodo,&nbsp;Minoru Yamada,&nbsp;Masakatsu Tsurusaki,&nbsp;Kazunari Ishii","doi":"10.22038/AOJNMB.2021.53427.1365","DOIUrl":"https://doi.org/10.22038/AOJNMB.2021.53427.1365","url":null,"abstract":"<p><strong>Objectives: </strong>To assess respiratory-gated (RG) positron emission tomography (PET) acquisition for patients with liver metastases during delayed PET/computed tomography (CT) scanning with fluorine-18-fluorodeoxyglucose (<sup>18</sup>F-FDG).</p><p><strong>Methods: </strong>Nineteen patients with liver metastases who had undergone early whole-body <sup>18</sup>F-FDG PET/CT scans without the RG technique and delayed scans with the RG technique were retrospectively selected. The maximum standardized uptake value (SUV<sub>max</sub>) of 41 liver lesions and the tumor-to-liver uptake ratios (TLRs) for these same lesions were compared among three data sets: early non-respiratory-gated (early non-RG) images, delayed non-respiratory-gated (delayed non-RG) images, and delayed respiratory-gated (delayed RG) images. In the delayed non-RG and delayed RG images, the improvements in the TLR, relative to the early non-RG images, were assessed according to lesion size.</p><p><strong>Results: </strong>For liver lesions, the SUV<sub>max</sub> of early non-RG, delayed non-RG, and delayed RG images were 6.58±2.34, 7.69±3.08, and 9.47±3.73, respectively. There were significant differences among the three images (P<0.01). The TLR of the delayed RG images was significantly higher than those of the early non-RG and delayed non-RG images (P<0.01). In the delayed RG images, the difference in the TLR improvement for lesions ≤10 mm in size was 15% higher than that for lesions >10 mm in size; in the delayed non-RG images, the difference in the TLR improvement for the same lesion categories was 6%.</p><p><strong>Conclusion: </strong>Delayed RG imaging improves the TLR, compared with early non-RG and delayed non-RG imaging, especially for small lesions. RG PET acquisition may be a promising protocol for assessing liver metastases on delayed PET/CT scans.</p>","PeriodicalId":8503,"journal":{"name":"Asia Oceania Journal of Nuclear Medicine and Biology","volume":"9 2","pages":"12-149"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255526/pdf/AOJNMB-9-142.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39175536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Sinus Tarsi Syndrome: Diagnosed on 99mTc-MDP bone SPECT/CT. 跗窦综合征:99mTc-MDP骨SPECT/CT诊断。
Asia Oceania Journal of Nuclear Medicine and Biology Pub Date : 2020-01-01 DOI: 10.22038/AOJNMB.2020.45897.1309
Abhishek Mahato, Partha B Mukherjee, Deepak Kumar Jha, A G Pandit, Vigneshwaran M
{"title":"Sinus Tarsi Syndrome: Diagnosed on <sup>99m</sup>Tc-MDP bone SPECT/CT.","authors":"Abhishek Mahato,&nbsp;Partha B Mukherjee,&nbsp;Deepak Kumar Jha,&nbsp;A G Pandit,&nbsp;Vigneshwaran M","doi":"10.22038/AOJNMB.2020.45897.1309","DOIUrl":"https://doi.org/10.22038/AOJNMB.2020.45897.1309","url":null,"abstract":"<p><p>Sinus Tarsi Syndrome is a cause of chronic ankle instability and pain. MRI of the ankle has been the modality of choice for diagnosing the condition. However, SPECT-CT offers an alternate modality for diagnosing and evaluation of the condition. We present the case of a footballer who was suffering from chronic right leg pain despite receiving physiotherapy. He was being managed as a case of a chronic ankle sprain. Meanwhile, he was referred to the department as radiology for MRI of the ankle could not be performed as the patient felt claustrophobic. The patient subsequently underwent a <sup>99m</sup>Tc-MDP Bone scan. He was diagnosed to be suffering from sinus tarsi syndrome as it showed a characteristic pattern noted on <sup>99m</sup>Tc-MDP Bone scintigraphy. This case report reveals the potential of SPECT-CT as an alternative in the evaluation of chronic ankle sprain to MRI in segment of cases where MRI is not performed due to various reasons.</p>","PeriodicalId":8503,"journal":{"name":"Asia Oceania Journal of Nuclear Medicine and Biology","volume":"8 2","pages":"153-156"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354248/pdf/AOJNMB-8-153.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38195265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Evaluation of D-isomer of 18F-FBPA for oncology PET focusing on the differentiation of glioma and inflammation. 18F-FBPA d -异构体对胶质瘤和炎症分化肿瘤PET的评价
Asia Oceania Journal of Nuclear Medicine and Biology Pub Date : 2020-01-01 DOI: 10.22038/AOJNMB.2020.47399.1321
Nobuto Hirai, Tadashi Watabe, Shushi Nagamori, Pattama Wiriyasermkul, Yoko Tanaka, Victor Romanov, Sadahiro Naka, Yasukazu Kanai, Yuwei Liu, Naoki Tani, Tatsuya Sakai, Mitsuaki Tatsumi, Eku Shimosegawa, Yoshikatsu Kanai, Jun Hatazawa
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引用次数: 2
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