Asia Oceania Journal of Nuclear Medicine and Biology最新文献

{"title":"Incidental Diagnosis of Multiple Paragangliomas by Ga-68 DOTANOC Positron Emission Tomography-Computed Tomography.","authors":"Vivek Kumar Saini,&nbsp;Akshay Kumar,&nbsp;Aftab Hasan Nazar,&nbsp;Manish Ora,&nbsp;Sanjay Gambhir","doi":"10.22038/AOJNMB.2021.17883","DOIUrl":"https://doi.org/10.22038/AOJNMB.2021.17883","url":null,"abstract":"<p><p>A 65-year-old man presented with intermittent abdominal pain for three months. Abdominal ultrasonography revealed a mass in the body of the pancreas. Moreover, abdominal contrast-enhancing computed tomography revealed a homogenously enhancing mass in the body of the pancreas. Scan findings were in favor of the neuroendocrine tumor, and the serum chromogranin level was slightly raised (111.9 ng/ml, normal <98). He had no history of vomiting, jaundice, melena, hematemesis, constipation, diarrhea, weight gain, weight loss, loss of appetite, and fever. He also had no symptoms related to the excessive production of catecholamines, such as hypertension. The patient was referred for Ga-68 DOTANOC positron emission tomography-computed tomography (Ga-68 DOTANOC PET-CT) for further evaluation. The scan was done to rule out metastatic disease or other synchronous lesions to plan surgical excision. The Ga-68 DOTANOC PET-CT revealed a pancreatic lesion with no other abdominal lesions. We noted multiple tracer avid soft tissue lesions on both sides of the neck that were not diagnosed previously. This case report demonstrates a rare case with multiple paragangliomas diagnosed by the Ga-68 DOTANOC PET-CT. This finding could lead to changes in patient management.</p>","PeriodicalId":8503,"journal":{"name":"Asia Oceania Journal of Nuclear Medicine and Biology","volume":"9 2","pages":"173-176"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255528/pdf/AOJNMB-9-173.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39174981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incremental Value of FDG PET/CT in Aggressive High Grade B Cell lymphoma with TdT Expression.","authors":"Nikita Sampathirao,&nbsp;Indirani Muthukrishnan,&nbsp;Ann Kurian,&nbsp;Jaykanth Amalchandran,&nbsp;Asra Patel,&nbsp;Shema Mathew,&nbsp;Shelley Simon","doi":"10.22038/AOJNMB.2020.48887.1332","DOIUrl":"https://doi.org/10.22038/AOJNMB.2020.48887.1332","url":null,"abstract":"<p><p>High-grade B-cell lymphoma, an aggressive form of Non-Hodgkin's Lymphoma, is known as a double or triple hit lymphoma based on the presence of MYC and BCL2 without or with BCL6 genetic rearrangements, respectively. It carries a poorer prognosis, compared to other variants of B-cell lymphoma, and its management also differs which requires more intensive chemotherapy in contrast to the routine regimen. Terminal deoxynucleotidyl transferase (TdT), a marker of immaturity is commonly expressed in B-cell lymphoblastic leukemia or lymphoma (B cell ALL) which is absent in mature forms of B-cell lymphoma. The TdT is expressed in high-grade B-cell lymphoma; therefore, it poses a classification and management dilemma, which should be accurately differentiated from B-cell ALL and mandates molecular analysis. Herein, we report a case of a 52-year-old female with biopsy reported as high-grade B-cell lymphoma with TdT expression. She was referred for Fluor-deoxyglucose (FDG) Positron Emission Tomography-Computed Tomography (PET/CT) scan for staging in the absence of molecular analysis for B-cell ALL. It was diagnosed as lymphoma on FDG PET/CT based on its characteristic findings of extensive extranodal involvement of multiple organs with no significant lymphadenopathy establishing the incremental value of FDG PET/CT scan, which helped the clinician to arrive at a conclusion.</p>","PeriodicalId":8503,"journal":{"name":"Asia Oceania Journal of Nuclear Medicine and Biology","volume":"9 1","pages":"45-50"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701230/pdf/AOJNMB-9-45.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38776326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Soft tissue metastasis of the penis detected by copper-64 labeled prostate-specific membrane antigen positron emission tomography (⁶⁴Cu-PSMA PET/CT) in a patient with prostate cancer.","authors":"Cherin Farhan,&nbsp;Siroos Mirzaei","doi":"10.22038/AOJNMB.2021.53922.1371","DOIUrl":"https://doi.org/10.22038/AOJNMB.2021.53922.1371","url":null,"abstract":"<p><p>Prostate cancer is considered to be the most common solid cancer affecting men worldwide and leading to a significant morbidity and mortality. Metastases are usually seen in bone or lymph nodes. For recurrent disease, PET imaging with ⁶⁸Ga-PSMA-11 (also known as HBED-CC, Glu-urea-Lys(Ahx)-HBED-CC, and PSMA-HBED-CC) is widely used. However, preparation of ⁶⁸Ga-PSMA ligand requires the presence of radiochemistry facilities and can therefore not be utilized in centers lacking such facilities. Recently, copper labeled prostate-specific membrane antigen positron emission tomography (⁶⁴Cu-PSMA PET/CT) demonstrated promising results in patients with recurrent disease and in the primary staging of selected patients with progressive local disease. In the present case, a rare manifestation site of a metastatic lesion in a patient with advanced prostate cancer is detected by ⁶⁴Cu-PSMA PET/CT.</p>","PeriodicalId":8503,"journal":{"name":"Asia Oceania Journal of Nuclear Medicine and Biology","volume":"9 2","pages":"180-182"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255521/pdf/AOJNMB-9-180.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39174983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sentinel lymph node biopsy for papillary thyroid cancer: the effect of dose, tracer and application of massage.","authors":"Abbas Alibakhshi,&nbsp;Saeed Farzanehfar,&nbsp;Mahya Zarei,&nbsp;Mohammad Eftekhari,&nbsp;Maziar Motiee,&nbsp;Maryam Naseri,&nbsp;Mehrshad Abbasi","doi":"10.22038/AOJNMB.2020.50491.1345","DOIUrl":"https://doi.org/10.22038/AOJNMB.2020.50491.1345","url":null,"abstract":"Objectives In patients with papillary thyroid cancer (PTC), sentinel lymph node (SLN) radio-guided biopsy is not routinely used for detection of involved neck lymph nodes (NLN); 99mTc- antimony sulfide colloid (99mTc- ASC) has been used for this purpose. In this study, besides 99mTc-ASC another radiotracer, 99mTc-phytate (99mTc-P) with different doses and injection methods were evaluated. Methods Twenty-two patients, scheduled to undergo thyroidectomy for PTC, were injected for radio-guided SLN biopsy in the morning of operation in 3 groups: intra tumoral injection of about 1 mCi 99mTc-P (group A; n=5); peritumoral injection of less than 3 mCi 99mTc-ASC (group B; n=6); and peritumoral injection of 3 to 5 mCi 99mTc-ASC with application of massage (group C; n=9). A patient refused to complete the study. A patient with follicular thyroid cancer was also excluded. No NLN was detected in the pre-operative ultra-sonographic examinations of all patients. Central neck dissection was done for all the participants. The presence of radio guided detected NLN and results of pathology were assessed. Results In group A and B, no SLN was detected. NLNs were resected in 4 patients in group A and B; 2 of them involved by the tumor. In group C, 6 out of 9 patients (66.7%) had between 1 to 6 SLNs; the procedure failed to detect NLN in a patient in group C with surgically resected reactive NLN (failure rate 1 out of 7). Conclusion The results underscored the significance of SLN radio guided biopsy in patients with PTC; the radiotracer, dose and method of injection may affect the detection rate.","PeriodicalId":8503,"journal":{"name":"Asia Oceania Journal of Nuclear Medicine and Biology","volume":"9 1","pages":"9-14"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701222/pdf/AOJNMB-9-09.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39123958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sectional Anatomy Quiz - VI.","authors":"Dinuli S Kamaladasa,&nbsp;Rashid Hashmi","doi":"10.22038/AOJNMB.2021.54904.1375","DOIUrl":"https://doi.org/10.22038/AOJNMB.2021.54904.1375","url":null,"abstract":"<p><p>This quiz is part of a series which aims to aid nuclear physicians in interpreting the computed tomography (CT) component of the single photon emission computed tomography (SPECT) and positron emission tomography (PET) studies. The current quiz includes normal and pathological axial CT images at the level of the superior mesenteric artery (SMA) and superior mesenteric vein (SMV). The SMV is normally located to the right of the SMA and is of a larger caliber. Various pathologies such as malignancy, infection or vascular disease can alter the position and/or appearance of the SMA, SMV and the surrounding anatomical structures present at this level. Understanding how normal anatomy is altered by pathology at this level will facilitate improved interpretation of abdominal CT images.</p>","PeriodicalId":8503,"journal":{"name":"Asia Oceania Journal of Nuclear Medicine and Biology","volume":"9 2","pages":"220-224"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255532/pdf/AOJNMB-9-220.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39174921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current state of oncologic ¹⁸F-FDG PET/CT in Japan: A nationwide survey.","authors":"Hajime Ichikawa,&nbsp;Toyohiro Kato,&nbsp;Kenta Miwa,&nbsp;Takayuki Shibutani,&nbsp;Koichi Okuda,&nbsp;Akio Nagaki,&nbsp;Hiroyuki Tsushima,&nbsp;Masahisa Onoguchi","doi":"10.22038/AOJNMB.2021.53693.1369","DOIUrl":"https://doi.org/10.22038/AOJNMB.2021.53693.1369","url":null,"abstract":"<p><strong>Objectives: </strong>Combined positron emission tomography/computed tomography (PET/CT) has gradually advanced with the introduction of newly developed techniques. However, the recent status of imaging techniques (e.g., scanning range, availability of correction methods, and decisions on performing delayed scan) in oncologic PET/CT with ¹⁸F-fluorodeoxyglucose (¹⁸F-FDG) in Japan is unclear. We conducted a nationwide cross-sectional survey to document ¹⁸F-FDG PET/CT protocols and clarify the recent status of imaging techniques for oncologic ¹⁸F-FDG PET/CT in Japan.</p><p><strong>Methods: </strong>We conducted a web survey hosted by the Japanese Society of Radiological Technology between October and December 2017. The questionnaire included nine items on the demographics of the respondents, their scan protocols, and additional imaging to their routine protocols.</p><p><strong>Results: </strong>We received responses from 119 Japanese technologists who performed ¹⁸F-FDG PET/CT in practice. Almost all the respondents stated that the scanning range was from the top of the head to the pelvis or mid-thigh region. Newly developed techniques were used by fewer than half of the respondents. Most respondents performed additional imaging in consultation with physicians, such as delayed imaging (83%) or an extended scanning range for early imaging (55%).</p><p><strong>Conclusions: </strong>Our survey helps in clarifying the recent state of oncologic ¹⁸F-FDG PET/CT imaging techniques in Japan. Given that ¹⁸F-FDG PET/CT practices most frequently performed additional imaging along with their routine scan protocol, the practice constitutes the most varied examination performed in Japanese nuclear medicine.</p>","PeriodicalId":8503,"journal":{"name":"Asia Oceania Journal of Nuclear Medicine and Biology","volume":"9 2","pages":"158-166"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255529/pdf/AOJNMB-9-158.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39174979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of the influence of CT slice thickness on the quantitative accuracy and image quality of single photon emission computed tomography.","authors":"Tomohiro Sato,&nbsp;Takashi Takagi","doi":"10.22038/AOJNMB.2021.54670.1376","DOIUrl":"https://doi.org/10.22038/AOJNMB.2021.54670.1376","url":null,"abstract":"<p><strong>Objectives: </strong>Computed tomography (CT) images are used for precise anatomical location of lesions and for accurate attenuation correction in single-photon emission computed tomography (SPECT) image reconstruction in SPECT/CT examination. The aim of this study was to verify the effects of varying CT collimation width and slice thickness on CT images and on CT attenuation corrected SPECT images.</p><p><strong>Methods: </strong>We acquired SPECT/CT images of a micro-coin phantom and the National Electrical Manufacturers Association body phantom filled with ^99mTc-pertechnetate while varying the abovementioned CT parameters. The full width at half maximum of the slice sensitivity profile, the standard deviation of CT image background noise, and the radiation dose from CT scans were evaluated. Subsequently, the percentage contrast, background variability, and absolute recovery coefficient of the SPECT image were measured. Furthermore, we retrospectively reviewed the clinical bone SPECT images of 23 patients, and statistical testing of differences was performed.</p><p><strong>Results: </strong>As the collimation width and reconstruction slice thickness of the CT image increased, z-axis resolution deteriorated, and background noise decreased. In addition, CT radiation dose decreased with increasing collimation width. Meanwhile, SPECT image quality and quantitative accuracy were unchanged with varying CT collimation width and slice thickness. There were no notable variations in clinical SPECT images and no statistically significant differences.</p><p><strong>Conclusion: </strong>When high-resolution CT slices on the z-axis are not required for clinical diagnosis, increasing collimation width or slice thickness can reduce the radiation dose and image noise with no influence on the quality of SPECT images <b><i>.</i></b></p>","PeriodicalId":8503,"journal":{"name":"Asia Oceania Journal of Nuclear Medicine and Biology","volume":"9 2","pages":"148-157"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255530/pdf/AOJNMB-9-148.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39174978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of regional cerebral perfusion impairment with gait and balance performance in dizzy patients using brain perfusion SPECT: Voxel-based analysis of a pilot sample.","authors":"Reza Nemati,&nbsp;Mohamad Ali Nayeri,&nbsp;Negar Chabi,&nbsp;Zahra Akbari,&nbsp;Esmail Jafari,&nbsp;Hossein Shooli,&nbsp;Habibollah Dadgar,&nbsp;Majid Assadi","doi":"10.22038/AOJNMB.2021.54974.1377","DOIUrl":"https://doi.org/10.22038/AOJNMB.2021.54974.1377","url":null,"abstract":"<p><strong>Objectives: </strong>The purpose of this study was to investigate regional cerebral blood flow (rCBF) reduction in patients with dizziness and perfusion-related clinical impairment using brain perfusion single photon emission tomography (SPECT).</p><p><strong>Methods: </strong>Thirty-four patients with subjective dizziness and 13 age- and sex-matched healthy controls were studied. Dizziness-related impairments were assessed using the Dizziness Handicap Inventory (DHI) and Short Physical Performance Battery (SPPB). Brain perfusion SPECT scan was acquired from all participants. The carotid intima-media thickness (CIMT) was also measured. Brain perfusion data were qualitatively interpreted in all cases. Voxel-wise analysis was also conducted in 11 patients compared to healthy controls.</p><p><strong>Results: </strong>Thirty-four patients (mean age=53.8±13.4 years, m/f: 19/15) and 13 age- and sex-matched controls (mean age=51.5±13.1, m/f: 7/6) were included. The dizziness severity was mild in 58.8% (n=20), moderate in 26.5% (n=9), and severe in 14.7% (n=5). Qualitative interpretation of SPECT images showed normal scans in 4 (11.2%) patients and abnormal scans in 30 (88.2%) patients. Patients with dizziness showed a significantly decreased brain perfusion in the precuneus, cuneus, occipital lobe (superior and inferior parts), frontal lobe (inferior and middle parts), temporal lobe, parietal lobe (inferior and superior parts), cerebellum, insula, and putamen nucleus. Based on both qualitative SPECT interpretation and voxel-wise analysis, perfusion defect had a significant association with the total SPPB score and the scores of two sub-domains (p<0.05), but not with the DHI (p>0.05) score.</p><p><strong>Conclusion: </strong>The perfusion- and atherosclerosis-related impairments of gait and balance were largely independent of subjective dizziness and dizziness severity. Moreover, this study provided support for contribution of perfusion impairment to the disturbance of gait and balance in older populations along with other pathologic processes.</p>","PeriodicalId":8503,"journal":{"name":"Asia Oceania Journal of Nuclear Medicine and Biology","volume":"9 2","pages":"123-130"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255531/pdf/AOJNMB-9-123.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39175540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unusual presentation of lumbar chordoma on bone scintigraphy in a young patient.","authors":"Yasaman Fakhar,&nbsp;Golnaz Gholami,&nbsp;Zahra Bakhshi Golestani,&nbsp;Ramin Sadeghi,&nbsp;Vahid Reza Dabbagh Kakhki","doi":"10.22038/AOJNMB.2020.48929.1331","DOIUrl":"https://doi.org/10.22038/AOJNMB.2020.48929.1331","url":null,"abstract":"<p><p>Chordoma is a rare bone cancer which arises from undifferentiated notochordal remnants in the axial skeleton. It generally has slow-growing and locally aggressive behavior. This tumor is usually diagnosed by CT and MRI modalities and the role of SPECT/CT is still debated. It shows reduced or normal uptake of radioisotope on bone scanning and increased tracer uptake is infrequently reported. Here we present a 33-year-old man with complaint of low back pain and numbness of his right leg. The whole body bone scan showed relatively uniform radiotracer activity throughout the skeleton. A focal increased uptake in the second lumbar vertebra was noted on SPECT/CT images. SPECT/CT also demonstrated multiple lytic lesions in lumbar vertebrae. The lesions were proven to be chordoma on biopsy. Lumbar chordoma could be one of the differential diagnoses for lytic lesions of the vertebrae which show absent or minimal tracer uptake on bone scintigraphy and SPECT/CT imaging. Our case was unusual as the patient was very young for chordoma diagnosis and bone scan showed increased uptake adjacent to the involved vertebral lesion detected by SPECT/CT.</p>","PeriodicalId":8503,"journal":{"name":"Asia Oceania Journal of Nuclear Medicine and Biology","volume":"9 1","pages":"76-79"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701223/pdf/AOJNMB-9-76.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38776332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"¹⁸F-FDG PET/CT in the Evaluation of Solitary Extramedullary Plasmacytoma: A Case Series.","authors":"Swati Rachh,&nbsp;Ketul Puj,&nbsp;Ankita Parikh","doi":"10.22038/AOJNMB.2020.49226.1335","DOIUrl":"https://doi.org/10.22038/AOJNMB.2020.49226.1335","url":null,"abstract":"<p><p>The role of fluorine-18-fluorodeoxyglucose positron emission tomography/ computed tomography (¹⁸F-FDG PET/CT) in patients with multiple myeloma (MM) and other plasma cell disorders is well-known. Solitary plasmacytoma (SP), an extremely rare form within this entity accounting for approximately 4% of plasma cell malignancies, can be classified as solitary bone plasmacytoma (SBP) or solitary extramedullary plasmacytoma (SEMP). Extramedullary plasmacytoma (EMP) is a rare neoplasm characterized by the monoclonal proliferation of plasma cells outside the bone marrow. Breast and craniocerebral regions are the uncommon sites of the presentations of EMP, rarely reported in the literature. The most frequent site of presentation is the upper airways. The EMPs have similar pathogenesis as MM; however, they differ in management as they are radiosensitive in nature, and radiotherapy is the preferred treatment modality. As SEMP has a better prognosis than SPB with a lower conversion rate to MM, accurate staging is essential to plan for the treatment. The ¹⁸F-FDG PET/CT has higher sensitivity for the evaluation of treatment response. In the present case series, it was aimed to depict the role of ¹⁸F-FDG PET/CT in newly diagnosed SEMP with different sites of origin to exclude further lesions leading to changes in the treatment plan and treatment response assessment.</p>","PeriodicalId":8503,"journal":{"name":"Asia Oceania Journal of Nuclear Medicine and Biology","volume":"9 1","pages":"56-61"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701227/pdf/AOJNMB-9-56.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38776328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}