{"title":"健康志愿者亚洲餐后心房收缩力:性别、月经、吸烟状况和年龄的影响","authors":"Janyarut Srijumruen, Sira Vachatimanont, Usanee Techavijit, Tawatchai Chaiwatanarat","doi":"10.22038/AOJNMB.2021.60453.1423","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>The normal range of the frequency of antral contractions, similar to other gastric motility parameters, are different depending on the population and the test meal. We, therefore, conducted the analysis to establish the normal ranges for the frequency of antral contractions derived from dynamic antral scintigraphy (DAS) following an Asian-styled solid meal in Thai healthy volunteers.</p><p><strong>Methods: </strong>We retrospectively analyzed the data from the study on normal gastric emptying values. The dynamic scintigraphic images had been obtained in a 45 degree left anterior oblique view during the first 32 minutes following the ingestion of a 267-kcal steamed rice, a technetium-99m-labeled microwaved egg and 100 mL of water. A polynomial normalization model was used to analyze and to calculate the frequency of antral contractions. The data analysis was repeated by the same operator 1 month apart to assess reproducibility.</p><p><strong>Results: </strong>Data of 18 volunteers (10 males and 8 females) were eligible for analysis. The mean±SD of the frequencies of the antral contractions were 3.06±1.08 cycles/min on the first and 3.04±1.10 cycles/min on the second analysis. Comparison of the two analyses revealed a moderate agreement (ICC=0.632, 95% CI 0.329-0.818) without significant difference (p-value=0.942). No significant effect of gender, menstruation status, smoking or age was demonstrated in this study.</p><p><strong>Conclusion: </strong>DAS is a non-invasive technique that can measure the frequency of antral contractions. The technique is reproducible and consistent. Future study may be required to assess the effect of gender, menstruation status, smoking and age.</p>","PeriodicalId":8503,"journal":{"name":"Asia Oceania Journal of Nuclear Medicine and Biology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205843/pdf/","citationCount":"0","resultStr":"{\"title\":\"Antral contractility following Asian-style meal in healthy volunteers: effect of genders, menstruation, smoking status and age.\",\"authors\":\"Janyarut Srijumruen, Sira Vachatimanont, Usanee Techavijit, Tawatchai Chaiwatanarat\",\"doi\":\"10.22038/AOJNMB.2021.60453.1423\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>The normal range of the frequency of antral contractions, similar to other gastric motility parameters, are different depending on the population and the test meal. We, therefore, conducted the analysis to establish the normal ranges for the frequency of antral contractions derived from dynamic antral scintigraphy (DAS) following an Asian-styled solid meal in Thai healthy volunteers.</p><p><strong>Methods: </strong>We retrospectively analyzed the data from the study on normal gastric emptying values. The dynamic scintigraphic images had been obtained in a 45 degree left anterior oblique view during the first 32 minutes following the ingestion of a 267-kcal steamed rice, a technetium-99m-labeled microwaved egg and 100 mL of water. A polynomial normalization model was used to analyze and to calculate the frequency of antral contractions. The data analysis was repeated by the same operator 1 month apart to assess reproducibility.</p><p><strong>Results: </strong>Data of 18 volunteers (10 males and 8 females) were eligible for analysis. The mean±SD of the frequencies of the antral contractions were 3.06±1.08 cycles/min on the first and 3.04±1.10 cycles/min on the second analysis. Comparison of the two analyses revealed a moderate agreement (ICC=0.632, 95% CI 0.329-0.818) without significant difference (p-value=0.942). No significant effect of gender, menstruation status, smoking or age was demonstrated in this study.</p><p><strong>Conclusion: </strong>DAS is a non-invasive technique that can measure the frequency of antral contractions. The technique is reproducible and consistent. 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引用次数: 0
摘要
目的:胃窦收缩频率的正常范围与其他胃动力参数相似,根据人群和试验餐的不同而不同。因此,我们对泰国健康志愿者进行了分析,以确定在亚洲式固体餐后,由动态心房扫描(DAS)得出的心房收缩频率的正常范围。方法:回顾性分析正常胃排空值的研究资料。在进食一顿267千卡的蒸米饭、一个锝-99m标记的微波鸡蛋和100毫升水后的前32分钟内,以45度左前斜角度获得动态闪烁图像。采用多项式归一化模型分析和计算心房收缩的频率。每隔1个月由同一操作者重复分析数据以评估再现性。结果:18名志愿者(男10名,女8名)的数据符合分析条件。第一次心房收缩频率的平均值±SD为3.06±1.08 cycles/min,第二次为3.04±1.10 cycles/min。两种分析的比较显示有中等程度的一致性(ICC=0.632, 95% CI 0.329-0.818),无显著差异(p值=0.942)。本研究未发现性别、月经状况、吸烟或年龄有显著影响。结论:DAS是一种无创的测量心房收缩频率的技术。该技术具有可重复性和一致性。未来的研究可能需要评估性别、月经状况、吸烟和年龄的影响。
Antral contractility following Asian-style meal in healthy volunteers: effect of genders, menstruation, smoking status and age.
Objectives: The normal range of the frequency of antral contractions, similar to other gastric motility parameters, are different depending on the population and the test meal. We, therefore, conducted the analysis to establish the normal ranges for the frequency of antral contractions derived from dynamic antral scintigraphy (DAS) following an Asian-styled solid meal in Thai healthy volunteers.
Methods: We retrospectively analyzed the data from the study on normal gastric emptying values. The dynamic scintigraphic images had been obtained in a 45 degree left anterior oblique view during the first 32 minutes following the ingestion of a 267-kcal steamed rice, a technetium-99m-labeled microwaved egg and 100 mL of water. A polynomial normalization model was used to analyze and to calculate the frequency of antral contractions. The data analysis was repeated by the same operator 1 month apart to assess reproducibility.
Results: Data of 18 volunteers (10 males and 8 females) were eligible for analysis. The mean±SD of the frequencies of the antral contractions were 3.06±1.08 cycles/min on the first and 3.04±1.10 cycles/min on the second analysis. Comparison of the two analyses revealed a moderate agreement (ICC=0.632, 95% CI 0.329-0.818) without significant difference (p-value=0.942). No significant effect of gender, menstruation status, smoking or age was demonstrated in this study.
Conclusion: DAS is a non-invasive technique that can measure the frequency of antral contractions. The technique is reproducible and consistent. Future study may be required to assess the effect of gender, menstruation status, smoking and age.